id author title date pages extension mime words sentences flesch summary cache txt cord-260087-9o9tb28h Furmanski, Martin The 1977 H1N1 Influenza Virus Reemergence Demonstrated Gain-of-Function Hazards 2015-09-29 .txt text/plain 648 34 45 R ozo and Gronvall, in "The Reemergent 1977 H1N1 Strain and the Gain-of-Function Debate" (1), confirmed the laboratory origin of the 1977 influenza pandemic and judged it was unintentional, but they concluded that its "relevance to GoF research is greatly diminished if the 1977 epidemic was the result of a vaccine trial or vaccine development gone awry; these are both more plausible explanations than a single laboratory accident." Rozo and Gronvall also stated that, "in 1977, influenza research was performed without modern biosafety regulations and protective equipment, making the lab accident hypothesis much less relevant to the modern GoF debate." However, the current record of containment of high-consequence pathogens is hardly reassuring. Activities at the select agent laboratory at the Tulane National Primate Research Center remain suspended after Burkholderia pseudomallei, the agent of melioidosis, escaped containment and caused multiple primate infections in an outdoor primate facility (5, 6) . ./cache/cord-260087-9o9tb28h.txt ./txt/cord-260087-9o9tb28h.txt