id sid tid token lemma pos cord-290297-efo9f7c5 1 1 key key NN cord-290297-efo9f7c5 1 2 : : : cord-290297-efo9f7c5 2 1 cord-290297-efo9f7c5 cord-290297-efo9f7c5 JJ cord-290297-efo9f7c5 2 2 authors author NNS cord-290297-efo9f7c5 2 3 : : : cord-290297-efo9f7c5 2 4 Vaillancourt Vaillancourt NNP cord-290297-efo9f7c5 2 5 , , , cord-290297-efo9f7c5 2 6 Mylene Mylene NNP cord-290297-efo9f7c5 2 7 ; ; : cord-290297-efo9f7c5 2 8 Jorth Jorth NNP cord-290297-efo9f7c5 2 9 , , , cord-290297-efo9f7c5 2 10 Peter Peter NNP cord-290297-efo9f7c5 2 11 title title NN cord-290297-efo9f7c5 2 12 : : : cord-290297-efo9f7c5 2 13 The the DT cord-290297-efo9f7c5 2 14 Unrecognized unrecognized JJ cord-290297-efo9f7c5 2 15 Threat threat NN cord-290297-efo9f7c5 2 16 of of IN cord-290297-efo9f7c5 2 17 Secondary secondary JJ cord-290297-efo9f7c5 2 18 Bacterial bacterial JJ cord-290297-efo9f7c5 2 19 Infections Infections NNPS cord-290297-efo9f7c5 2 20 with with IN cord-290297-efo9f7c5 2 21 COVID-19 covid-19 CD cord-290297-efo9f7c5 2 22 date date NN cord-290297-efo9f7c5 2 23 : : : cord-290297-efo9f7c5 2 24 2020 2020 CD cord-290297-efo9f7c5 2 25 - - HYPH cord-290297-efo9f7c5 2 26 08 08 CD cord-290297-efo9f7c5 2 27 - - HYPH cord-290297-efo9f7c5 2 28 07 07 CD cord-290297-efo9f7c5 2 29 journal journal NN cord-290297-efo9f7c5 2 30 : : : cord-290297-efo9f7c5 2 31 mBio mBio NNP cord-290297-efo9f7c5 3 1 DOI DOI NNP cord-290297-efo9f7c5 3 2 : : : cord-290297-efo9f7c5 4 1 10.1128 10.1128 CD cord-290297-efo9f7c5 4 2 / / SYM cord-290297-efo9f7c5 4 3 mbio.01806 mbio.01806 VBN cord-290297-efo9f7c5 4 4 - - HYPH cord-290297-efo9f7c5 4 5 20 20 CD cord-290297-efo9f7c5 4 6 sha sha NNP cord-290297-efo9f7c5 4 7 : : : cord-290297-efo9f7c5 4 8 8dfd5da42dfab63e479cba0c811a9c51dfa45d3e 8dfd5da42dfab63e479cba0c811a9c51dfa45d3e NNS cord-290297-efo9f7c5 4 9 doc_id doc_id CD cord-290297-efo9f7c5 4 10 : : : cord-290297-efo9f7c5 5 1 290297 290297 CD cord-290297-efo9f7c5 5 2 cord_uid cord_uid NNS cord-290297-efo9f7c5 5 3 : : : cord-290297-efo9f7c5 5 4 efo9f7c5 efo9f7c5 NN cord-290297-efo9f7c5 5 5 Coronavirus Coronavirus NNP cord-290297-efo9f7c5 5 6 disease disease NN cord-290297-efo9f7c5 5 7 2019 2019 CD cord-290297-efo9f7c5 5 8 ( ( -LRB- cord-290297-efo9f7c5 5 9 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 5 10 ) ) -RRB- cord-290297-efo9f7c5 5 11 is be VBZ cord-290297-efo9f7c5 5 12 the the DT cord-290297-efo9f7c5 5 13 greatest great JJS cord-290297-efo9f7c5 5 14 pandemic pandemic NN cord-290297-efo9f7c5 5 15 of of IN cord-290297-efo9f7c5 5 16 our -PRON- PRP$ cord-290297-efo9f7c5 5 17 generation generation NN cord-290297-efo9f7c5 5 18 , , , cord-290297-efo9f7c5 5 19 with with IN cord-290297-efo9f7c5 5 20 16 16 CD cord-290297-efo9f7c5 5 21 million million CD cord-290297-efo9f7c5 5 22 people people NNS cord-290297-efo9f7c5 5 23 affected affect VBN cord-290297-efo9f7c5 5 24 and and CC cord-290297-efo9f7c5 5 25 650,000 650,000 CD cord-290297-efo9f7c5 5 26 deaths death NNS cord-290297-efo9f7c5 5 27 worldwide worldwide RB cord-290297-efo9f7c5 5 28 so so RB cord-290297-efo9f7c5 5 29 far far RB cord-290297-efo9f7c5 5 30 . . . cord-290297-efo9f7c5 6 1 One one CD cord-290297-efo9f7c5 6 2 of of IN cord-290297-efo9f7c5 6 3 the the DT cord-290297-efo9f7c5 6 4 risk risk NN cord-290297-efo9f7c5 6 5 factors factor NNS cord-290297-efo9f7c5 6 6 associated associate VBN cord-290297-efo9f7c5 6 7 with with IN cord-290297-efo9f7c5 6 8 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 6 9 is be VBZ cord-290297-efo9f7c5 6 10 secondary secondary JJ cord-290297-efo9f7c5 6 11 bacterial bacterial JJ cord-290297-efo9f7c5 6 12 pneumonia pneumonia NN cord-290297-efo9f7c5 6 13 . . . cord-290297-efo9f7c5 7 1 In in IN cord-290297-efo9f7c5 7 2 recent recent JJ cord-290297-efo9f7c5 7 3 studies study NNS cord-290297-efo9f7c5 7 4 on on IN cord-290297-efo9f7c5 7 5 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 7 6 patients patient NNS cord-290297-efo9f7c5 7 7 , , , cord-290297-efo9f7c5 7 8 secondary secondary JJ cord-290297-efo9f7c5 7 9 bacterial bacterial JJ cord-290297-efo9f7c5 7 10 infections infection NNS cord-290297-efo9f7c5 7 11 were be VBD cord-290297-efo9f7c5 7 12 significantly significantly RB cord-290297-efo9f7c5 7 13 associated associate VBN cord-290297-efo9f7c5 7 14 with with IN cord-290297-efo9f7c5 7 15 worse bad JJR cord-290297-efo9f7c5 7 16 outcomes outcome NNS cord-290297-efo9f7c5 7 17 and and CC cord-290297-efo9f7c5 7 18 death death NN cord-290297-efo9f7c5 7 19 despite despite IN cord-290297-efo9f7c5 7 20 antimicrobial antimicrobial JJ cord-290297-efo9f7c5 7 21 therapies therapy NNS cord-290297-efo9f7c5 7 22 . . . cord-290297-efo9f7c5 8 1 In in IN cord-290297-efo9f7c5 8 2 the the DT cord-290297-efo9f7c5 8 3 past past NN cord-290297-efo9f7c5 8 4 , , , cord-290297-efo9f7c5 8 5 the the DT cord-290297-efo9f7c5 8 6 intensive intensive JJ cord-290297-efo9f7c5 8 7 use use NN cord-290297-efo9f7c5 8 8 of of IN cord-290297-efo9f7c5 8 9 antibiotics antibiotic NNS cord-290297-efo9f7c5 8 10 during during IN cord-290297-efo9f7c5 8 11 the the DT cord-290297-efo9f7c5 8 12 severe severe JJ cord-290297-efo9f7c5 8 13 acute acute JJ cord-290297-efo9f7c5 8 14 respiratory respiratory JJ cord-290297-efo9f7c5 8 15 syndrome syndrome NN cord-290297-efo9f7c5 8 16 coronavirus coronavirus NN cord-290297-efo9f7c5 8 17 ( ( -LRB- cord-290297-efo9f7c5 8 18 SARS SARS NNP cord-290297-efo9f7c5 8 19 - - HYPH cord-290297-efo9f7c5 8 20 CoV CoV NNP cord-290297-efo9f7c5 8 21 ) ) -RRB- cord-290297-efo9f7c5 8 22 pandemic pandemic NN cord-290297-efo9f7c5 8 23 led lead VBD cord-290297-efo9f7c5 8 24 to to IN cord-290297-efo9f7c5 8 25 increases increase NNS cord-290297-efo9f7c5 8 26 in in IN cord-290297-efo9f7c5 8 27 the the DT cord-290297-efo9f7c5 8 28 prevalence prevalence NN cord-290297-efo9f7c5 8 29 of of IN cord-290297-efo9f7c5 8 30 multidrug multidrug NN cord-290297-efo9f7c5 8 31 - - HYPH cord-290297-efo9f7c5 8 32 resistant resistant JJ cord-290297-efo9f7c5 8 33 bacteria bacteria NNS cord-290297-efo9f7c5 8 34 . . . cord-290297-efo9f7c5 9 1 The the DT cord-290297-efo9f7c5 9 2 rising rise VBG cord-290297-efo9f7c5 9 3 number number NN cord-290297-efo9f7c5 9 4 of of IN cord-290297-efo9f7c5 9 5 antibiotic antibiotic JJ cord-290297-efo9f7c5 9 6 - - HYPH cord-290297-efo9f7c5 9 7 resistant resistant JJ cord-290297-efo9f7c5 9 8 bacteria bacteria NNS cord-290297-efo9f7c5 9 9 and and CC cord-290297-efo9f7c5 9 10 our -PRON- PRP$ cord-290297-efo9f7c5 9 11 decreasing decrease VBG cord-290297-efo9f7c5 9 12 capacity capacity NN cord-290297-efo9f7c5 9 13 to to TO cord-290297-efo9f7c5 9 14 eradicate eradicate VB cord-290297-efo9f7c5 9 15 them -PRON- PRP cord-290297-efo9f7c5 9 16 not not RB cord-290297-efo9f7c5 9 17 only only RB cord-290297-efo9f7c5 9 18 render render VB cord-290297-efo9f7c5 9 19 us -PRON- PRP cord-290297-efo9f7c5 9 20 more more RBR cord-290297-efo9f7c5 9 21 vulnerable vulnerable JJ cord-290297-efo9f7c5 9 22 to to IN cord-290297-efo9f7c5 9 23 bacterial bacterial JJ cord-290297-efo9f7c5 9 24 infections infection NNS cord-290297-efo9f7c5 9 25 but but CC cord-290297-efo9f7c5 9 26 also also RB cord-290297-efo9f7c5 9 27 weaken weaken VB cord-290297-efo9f7c5 9 28 us -PRON- PRP cord-290297-efo9f7c5 9 29 during during IN cord-290297-efo9f7c5 9 30 viral viral JJ cord-290297-efo9f7c5 9 31 pandemics pandemic NNS cord-290297-efo9f7c5 9 32 . . . cord-290297-efo9f7c5 10 1 The the DT cord-290297-efo9f7c5 10 2 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 10 3 pandemic pandemic NN cord-290297-efo9f7c5 10 4 reminds remind VBZ cord-290297-efo9f7c5 10 5 us -PRON- PRP cord-290297-efo9f7c5 10 6 of of IN cord-290297-efo9f7c5 10 7 the the DT cord-290297-efo9f7c5 10 8 great great JJ cord-290297-efo9f7c5 10 9 health health NN cord-290297-efo9f7c5 10 10 challenges challenge NNS cord-290297-efo9f7c5 10 11 we -PRON- PRP cord-290297-efo9f7c5 10 12 are be VBP cord-290297-efo9f7c5 10 13 facing face VBG cord-290297-efo9f7c5 10 14 , , , cord-290297-efo9f7c5 10 15 especially especially RB cord-290297-efo9f7c5 10 16 regarding regard VBG cord-290297-efo9f7c5 10 17 antibiotic antibiotic JJ cord-290297-efo9f7c5 10 18 - - HYPH cord-290297-efo9f7c5 10 19 resistant resistant JJ cord-290297-efo9f7c5 10 20 bacteria bacteria NNS cord-290297-efo9f7c5 10 21 . . . cord-290297-efo9f7c5 11 1 T T NNP cord-290297-efo9f7c5 11 2 he -PRON- PRP cord-290297-efo9f7c5 11 3 outbreak outbreak NN cord-290297-efo9f7c5 11 4 of of IN cord-290297-efo9f7c5 11 5 severe severe JJ cord-290297-efo9f7c5 11 6 acute acute JJ cord-290297-efo9f7c5 11 7 respiratory respiratory JJ cord-290297-efo9f7c5 11 8 syndrome syndrome NN cord-290297-efo9f7c5 11 9 coronavirus coronavirus NN cord-290297-efo9f7c5 11 10 2 2 CD cord-290297-efo9f7c5 12 1 ( ( -LRB- cord-290297-efo9f7c5 12 2 SARS SARS NNP cord-290297-efo9f7c5 12 3 - - HYPH cord-290297-efo9f7c5 12 4 CoV-2 CoV-2 NNP cord-290297-efo9f7c5 12 5 ) ) -RRB- cord-290297-efo9f7c5 12 6 , , , cord-290297-efo9f7c5 12 7 which which WDT cord-290297-efo9f7c5 12 8 causes cause VBZ cord-290297-efo9f7c5 12 9 coronavirus coronavirus NN cord-290297-efo9f7c5 12 10 disease disease NN cord-290297-efo9f7c5 12 11 2019 2019 CD cord-290297-efo9f7c5 12 12 ( ( -LRB- cord-290297-efo9f7c5 12 13 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 12 14 ) ) -RRB- cord-290297-efo9f7c5 12 15 , , , cord-290297-efo9f7c5 12 16 is be VBZ cord-290297-efo9f7c5 12 17 the the DT cord-290297-efo9f7c5 12 18 greatest great JJS cord-290297-efo9f7c5 12 19 pandemic pandemic NN cord-290297-efo9f7c5 12 20 of of IN cord-290297-efo9f7c5 12 21 our -PRON- PRP$ cord-290297-efo9f7c5 12 22 generation generation NN cord-290297-efo9f7c5 12 23 , , , cord-290297-efo9f7c5 12 24 with with IN cord-290297-efo9f7c5 12 25 16 16 CD cord-290297-efo9f7c5 12 26 million million CD cord-290297-efo9f7c5 12 27 people people NNS cord-290297-efo9f7c5 12 28 infected infect VBN cord-290297-efo9f7c5 12 29 and and CC cord-290297-efo9f7c5 12 30 650,000 650,000 CD cord-290297-efo9f7c5 12 31 deaths death NNS cord-290297-efo9f7c5 12 32 worldwide worldwide RB cord-290297-efo9f7c5 12 33 so so RB cord-290297-efo9f7c5 12 34 far far RB cord-290297-efo9f7c5 12 35 ( ( -LRB- cord-290297-efo9f7c5 12 36 1 1 CD cord-290297-efo9f7c5 12 37 ) ) -RRB- cord-290297-efo9f7c5 12 38 . . . cord-290297-efo9f7c5 13 1 One one CD cord-290297-efo9f7c5 13 2 of of IN cord-290297-efo9f7c5 13 3 the the DT cord-290297-efo9f7c5 13 4 great great JJ cord-290297-efo9f7c5 13 5 mysteries mystery NNS cord-290297-efo9f7c5 13 6 in in IN cord-290297-efo9f7c5 13 7 this this DT cord-290297-efo9f7c5 13 8 pandemic pandemic NN cord-290297-efo9f7c5 13 9 is be VBZ cord-290297-efo9f7c5 13 10 why why WRB cord-290297-efo9f7c5 13 11 some some DT cord-290297-efo9f7c5 13 12 people people NNS cord-290297-efo9f7c5 13 13 become become VBP cord-290297-efo9f7c5 13 14 critically critically RB cord-290297-efo9f7c5 13 15 ill ill JJ cord-290297-efo9f7c5 13 16 while while IN cord-290297-efo9f7c5 13 17 others other NNS cord-290297-efo9f7c5 13 18 exhibit exhibit VBP cord-290297-efo9f7c5 13 19 relatively relatively RB cord-290297-efo9f7c5 13 20 mild mild JJ cord-290297-efo9f7c5 13 21 symptoms symptom NNS cord-290297-efo9f7c5 13 22 , , , cord-290297-efo9f7c5 13 23 even even RB cord-290297-efo9f7c5 13 24 when when WRB cord-290297-efo9f7c5 13 25 the the DT cord-290297-efo9f7c5 13 26 patients patient NNS cord-290297-efo9f7c5 13 27 share share VBP cord-290297-efo9f7c5 13 28 similar similar JJ cord-290297-efo9f7c5 13 29 risk risk NN cord-290297-efo9f7c5 13 30 factors factor NNS cord-290297-efo9f7c5 13 31 . . . cord-290297-efo9f7c5 14 1 It -PRON- PRP cord-290297-efo9f7c5 14 2 is be VBZ cord-290297-efo9f7c5 14 3 becoming become VBG cord-290297-efo9f7c5 14 4 apparent apparent JJ cord-290297-efo9f7c5 14 5 that that IN cord-290297-efo9f7c5 14 6 secondary secondary JJ cord-290297-efo9f7c5 14 7 bacterial bacterial JJ cord-290297-efo9f7c5 14 8 infections infection NNS cord-290297-efo9f7c5 14 9 occur occur VBP cord-290297-efo9f7c5 14 10 in in IN cord-290297-efo9f7c5 14 11 many many JJ cord-290297-efo9f7c5 14 12 COVID-19 covid-19 JJ cord-290297-efo9f7c5 14 13 patients patient NNS cord-290297-efo9f7c5 14 14 and and CC cord-290297-efo9f7c5 14 15 can can MD cord-290297-efo9f7c5 14 16 be be VB cord-290297-efo9f7c5 14 17 associated associate VBN cord-290297-efo9f7c5 14 18 with with IN cord-290297-efo9f7c5 14 19 worse bad JJR cord-290297-efo9f7c5 14 20 outcomes outcome NNS cord-290297-efo9f7c5 14 21 . . . cord-290297-efo9f7c5 15 1 In in IN cord-290297-efo9f7c5 15 2 a a DT cord-290297-efo9f7c5 15 3 multicenter multicenter JJ cord-290297-efo9f7c5 15 4 study study NN cord-290297-efo9f7c5 15 5 that that WDT cord-290297-efo9f7c5 15 6 included include VBD cord-290297-efo9f7c5 15 7 476 476 CD cord-290297-efo9f7c5 15 8 COVID-19 covid-19 CD cord-290297-efo9f7c5 15 9 patients patient NNS cord-290297-efo9f7c5 15 10 , , , cord-290297-efo9f7c5 15 11 secondary secondary JJ cord-290297-efo9f7c5 15 12 bacterial bacterial JJ cord-290297-efo9f7c5 15 13 infections infection NNS cord-290297-efo9f7c5 15 14 were be VBD cord-290297-efo9f7c5 15 15 significantly significantly RB cord-290297-efo9f7c5 15 16 associated associate VBN cord-290297-efo9f7c5 15 17 with with IN cord-290297-efo9f7c5 15 18 outcome outcome NN cord-290297-efo9f7c5 15 19 severity severity NN cord-290297-efo9f7c5 15 20 ( ( -LRB- cord-290297-efo9f7c5 15 21 2 2 CD cord-290297-efo9f7c5 15 22 ) ) -RRB- cord-290297-efo9f7c5 15 23 . . . cord-290297-efo9f7c5 16 1 In in IN cord-290297-efo9f7c5 16 2 that that DT cord-290297-efo9f7c5 16 3 study study NN cord-290297-efo9f7c5 16 4 , , , cord-290297-efo9f7c5 16 5 patients patient NNS cord-290297-efo9f7c5 16 6 were be VBD cord-290297-efo9f7c5 16 7 divided divide VBN cord-290297-efo9f7c5 16 8 into into IN cord-290297-efo9f7c5 16 9 3 3 CD cord-290297-efo9f7c5 16 10 groups group NNS cord-290297-efo9f7c5 16 11 ( ( -LRB- cord-290297-efo9f7c5 16 12 moderately moderately RB cord-290297-efo9f7c5 16 13 ill ill JJ cord-290297-efo9f7c5 16 14 , , , cord-290297-efo9f7c5 16 15 severely severely RB cord-290297-efo9f7c5 16 16 ill ill JJ cord-290297-efo9f7c5 16 17 , , , cord-290297-efo9f7c5 16 18 and and CC cord-290297-efo9f7c5 16 19 critically critically RB cord-290297-efo9f7c5 16 20 ill ill JJ cord-290297-efo9f7c5 16 21 ) ) -RRB- cord-290297-efo9f7c5 16 22 . . . cord-290297-efo9f7c5 17 1 The the DT cord-290297-efo9f7c5 17 2 critically critically RB cord-290297-efo9f7c5 17 3 ill ill JJ cord-290297-efo9f7c5 17 4 patients patient NNS cord-290297-efo9f7c5 17 5 had have VBD cord-290297-efo9f7c5 17 6 the the DT cord-290297-efo9f7c5 17 7 highest high JJS cord-290297-efo9f7c5 17 8 percentage percentage NN cord-290297-efo9f7c5 17 9 of of IN cord-290297-efo9f7c5 17 10 bacterial bacterial JJ cord-290297-efo9f7c5 17 11 coinfection coinfection NN cord-290297-efo9f7c5 17 12 ( ( -LRB- cord-290297-efo9f7c5 17 13 34.5 34.5 CD cord-290297-efo9f7c5 17 14 % % NN cord-290297-efo9f7c5 17 15 ) ) -RRB- cord-290297-efo9f7c5 17 16 compared compare VBN cord-290297-efo9f7c5 17 17 to to IN cord-290297-efo9f7c5 17 18 patients patient NNS cord-290297-efo9f7c5 17 19 in in IN cord-290297-efo9f7c5 17 20 the the DT cord-290297-efo9f7c5 17 21 moderately moderately RB cord-290297-efo9f7c5 17 22 ill ill JJ cord-290297-efo9f7c5 17 23 and and CC cord-290297-efo9f7c5 17 24 severely severely RB cord-290297-efo9f7c5 17 25 ill ill JJ cord-290297-efo9f7c5 17 26 groups group NNS cord-290297-efo9f7c5 17 27 ( ( -LRB- cord-290297-efo9f7c5 17 28 3.9 3.9 CD cord-290297-efo9f7c5 17 29 % % NN cord-290297-efo9f7c5 17 30 and and CC cord-290297-efo9f7c5 17 31 8.3 8.3 CD cord-290297-efo9f7c5 17 32 % % NN cord-290297-efo9f7c5 17 33 , , , cord-290297-efo9f7c5 17 34 respectively respectively RB cord-290297-efo9f7c5 17 35 ) ) -RRB- cord-290297-efo9f7c5 17 36 ( ( -LRB- cord-290297-efo9f7c5 17 37 2 2 CD cord-290297-efo9f7c5 17 38 ) ) -RRB- cord-290297-efo9f7c5 17 39 . . . cord-290297-efo9f7c5 18 1 More more RBR cord-290297-efo9f7c5 18 2 concerning concern VBG cord-290297-efo9f7c5 18 3 , , , cord-290297-efo9f7c5 18 4 this this DT cord-290297-efo9f7c5 18 5 higher high JJR cord-290297-efo9f7c5 18 6 rate rate NN cord-290297-efo9f7c5 18 7 of of IN cord-290297-efo9f7c5 18 8 coinfections coinfection NNS cord-290297-efo9f7c5 18 9 in in IN cord-290297-efo9f7c5 18 10 critical critical JJ cord-290297-efo9f7c5 18 11 patients patient NNS cord-290297-efo9f7c5 18 12 happened happen VBD cord-290297-efo9f7c5 18 13 although although IN cord-290297-efo9f7c5 18 14 the the DT cord-290297-efo9f7c5 18 15 majority majority NN cord-290297-efo9f7c5 18 16 of of IN cord-290297-efo9f7c5 18 17 them -PRON- PRP cord-290297-efo9f7c5 18 18 ( ( -LRB- cord-290297-efo9f7c5 18 19 92.9 92.9 CD cord-290297-efo9f7c5 18 20 % % NN cord-290297-efo9f7c5 18 21 ) ) -RRB- cord-290297-efo9f7c5 18 22 received receive VBD cord-290297-efo9f7c5 18 23 antibiotic antibiotic JJ cord-290297-efo9f7c5 18 24 treatments treatment NNS cord-290297-efo9f7c5 18 25 compared compare VBN cord-290297-efo9f7c5 18 26 to to IN cord-290297-efo9f7c5 18 27 59.4 59.4 CD cord-290297-efo9f7c5 18 28 % % NN cord-290297-efo9f7c5 18 29 and and CC cord-290297-efo9f7c5 18 30 83.3 83.3 CD cord-290297-efo9f7c5 18 31 % % NN cord-290297-efo9f7c5 18 32 in in IN cord-290297-efo9f7c5 18 33 the the DT cord-290297-efo9f7c5 18 34 moderately moderately RB cord-290297-efo9f7c5 18 35 ill ill JJ cord-290297-efo9f7c5 18 36 and and CC cord-290297-efo9f7c5 18 37 severely severely RB cord-290297-efo9f7c5 18 38 ill ill JJ cord-290297-efo9f7c5 18 39 groups group NNS cord-290297-efo9f7c5 18 40 . . . cord-290297-efo9f7c5 19 1 Zhou Zhou NNP cord-290297-efo9f7c5 19 2 and and CC cord-290297-efo9f7c5 19 3 colleagues colleague NNS cord-290297-efo9f7c5 19 4 ( ( -LRB- cord-290297-efo9f7c5 19 5 3 3 LS cord-290297-efo9f7c5 19 6 ) ) -RRB- cord-290297-efo9f7c5 19 7 also also RB cord-290297-efo9f7c5 19 8 found find VBD cord-290297-efo9f7c5 19 9 that that IN cord-290297-efo9f7c5 19 10 among among IN cord-290297-efo9f7c5 19 11 191 191 CD cord-290297-efo9f7c5 19 12 COVID-19 covid-19 CD cord-290297-efo9f7c5 19 13 patients patient NNS cord-290297-efo9f7c5 19 14 , , , cord-290297-efo9f7c5 19 15 bacterial bacterial JJ cord-290297-efo9f7c5 19 16 coinfections coinfection NNS cord-290297-efo9f7c5 19 17 occurred occur VBD cord-290297-efo9f7c5 19 18 in in IN cord-290297-efo9f7c5 19 19 15 15 CD cord-290297-efo9f7c5 19 20 % % NN cord-290297-efo9f7c5 19 21 of of IN cord-290297-efo9f7c5 19 22 all all DT cord-290297-efo9f7c5 19 23 cases case NNS cord-290297-efo9f7c5 19 24 , , , cord-290297-efo9f7c5 19 25 including include VBG cord-290297-efo9f7c5 19 26 50 50 CD cord-290297-efo9f7c5 19 27 % % NN cord-290297-efo9f7c5 19 28 of of IN cord-290297-efo9f7c5 19 29 nonsurvivors nonsurvivor NNS cord-290297-efo9f7c5 19 30 , , , cord-290297-efo9f7c5 19 31 even even RB cord-290297-efo9f7c5 19 32 though though IN cord-290297-efo9f7c5 19 33 95 95 CD cord-290297-efo9f7c5 19 34 % % NN cord-290297-efo9f7c5 19 35 of of IN cord-290297-efo9f7c5 19 36 patients patient NNS cord-290297-efo9f7c5 19 37 received receive VBD cord-290297-efo9f7c5 19 38 antibiotics antibiotic NNS cord-290297-efo9f7c5 19 39 . . . cord-290297-efo9f7c5 20 1 Even even RB cord-290297-efo9f7c5 20 2 more more RBR cord-290297-efo9f7c5 20 3 troubling troubling JJ cord-290297-efo9f7c5 20 4 , , , cord-290297-efo9f7c5 20 5 27/28 27/28 CD cord-290297-efo9f7c5 20 6 COVID-19 covid-19 CD cord-290297-efo9f7c5 20 7 patients patient NNS cord-290297-efo9f7c5 20 8 with with IN cord-290297-efo9f7c5 20 9 coinfections coinfection NNS cord-290297-efo9f7c5 20 10 succumbed succumb VBD cord-290297-efo9f7c5 20 11 ( ( -LRB- cord-290297-efo9f7c5 20 12 3 3 CD cord-290297-efo9f7c5 20 13 ) ) -RRB- cord-290297-efo9f7c5 20 14 . . . cord-290297-efo9f7c5 21 1 In in IN cord-290297-efo9f7c5 21 2 both both DT cord-290297-efo9f7c5 21 3 studies study NNS cord-290297-efo9f7c5 21 4 , , , cord-290297-efo9f7c5 21 5 other other JJ cord-290297-efo9f7c5 21 6 comorbidities comorbiditie NNS cord-290297-efo9f7c5 21 7 were be VBD cord-290297-efo9f7c5 21 8 also also RB cord-290297-efo9f7c5 21 9 associated associate VBN cord-290297-efo9f7c5 21 10 with with IN cord-290297-efo9f7c5 21 11 mortality mortality NN cord-290297-efo9f7c5 21 12 ; ; : cord-290297-efo9f7c5 21 13 thus thus RB cord-290297-efo9f7c5 21 14 , , , cord-290297-efo9f7c5 21 15 it -PRON- PRP cord-290297-efo9f7c5 21 16 is be VBZ cord-290297-efo9f7c5 21 17 difficult difficult JJ cord-290297-efo9f7c5 21 18 to to TO cord-290297-efo9f7c5 21 19 determine determine VB cord-290297-efo9f7c5 21 20 the the DT cord-290297-efo9f7c5 21 21 exact exact JJ cord-290297-efo9f7c5 21 22 impact impact NN cord-290297-efo9f7c5 21 23 of of IN cord-290297-efo9f7c5 21 24 coinfections coinfection NNS cord-290297-efo9f7c5 21 25 . . . cord-290297-efo9f7c5 22 1 A a DT cord-290297-efo9f7c5 22 2 third third JJ cord-290297-efo9f7c5 22 3 study study NN cord-290297-efo9f7c5 22 4 ( ( -LRB- cord-290297-efo9f7c5 22 5 4 4 LS cord-290297-efo9f7c5 22 6 ) ) -RRB- cord-290297-efo9f7c5 22 7 used use VBN cord-290297-efo9f7c5 22 8 real real JJ cord-290297-efo9f7c5 22 9 - - HYPH cord-290297-efo9f7c5 22 10 time time NN cord-290297-efo9f7c5 22 11 PCR PCR NNP cord-290297-efo9f7c5 22 12 to to TO cord-290297-efo9f7c5 22 13 detect detect VB cord-290297-efo9f7c5 22 14 specific specific JJ cord-290297-efo9f7c5 22 15 pathogens pathogen NNS cord-290297-efo9f7c5 22 16 causing cause VBG cord-290297-efo9f7c5 22 17 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 22 18 coinfections coinfection NNS cord-290297-efo9f7c5 22 19 . . . cord-290297-efo9f7c5 23 1 They -PRON- PRP cord-290297-efo9f7c5 23 2 found find VBD cord-290297-efo9f7c5 23 3 that that IN cord-290297-efo9f7c5 23 4 243 243 CD cord-290297-efo9f7c5 23 5 ( ( -LRB- cord-290297-efo9f7c5 23 6 94.2 94.2 CD cord-290297-efo9f7c5 23 7 % % NN cord-290297-efo9f7c5 23 8 ) ) -RRB- cord-290297-efo9f7c5 23 9 patients patient NNS cord-290297-efo9f7c5 23 10 were be VBD cord-290297-efo9f7c5 23 11 coinfected coinfecte VBN cord-290297-efo9f7c5 23 12 with with IN cord-290297-efo9f7c5 23 13 at at RB cord-290297-efo9f7c5 23 14 least least JJS cord-290297-efo9f7c5 23 15 1 1 CD cord-290297-efo9f7c5 23 16 of of IN cord-290297-efo9f7c5 23 17 39 39 CD cord-290297-efo9f7c5 23 18 different different JJ cord-290297-efo9f7c5 23 19 pathogens pathogen NNS cord-290297-efo9f7c5 23 20 . . . cord-290297-efo9f7c5 24 1 Bacterial bacterial JJ cord-290297-efo9f7c5 24 2 coinfections coinfection NNS cord-290297-efo9f7c5 24 3 were be VBD cord-290297-efo9f7c5 24 4 predominant predominant JJ cord-290297-efo9f7c5 24 5 ( ( -LRB- cord-290297-efo9f7c5 24 6 91.8 91.8 CD cord-290297-efo9f7c5 24 7 % % NN cord-290297-efo9f7c5 24 8 ) ) -RRB- cord-290297-efo9f7c5 24 9 over over IN cord-290297-efo9f7c5 24 10 viral viral JJ cord-290297-efo9f7c5 24 11 ( ( -LRB- cord-290297-efo9f7c5 24 12 31.5 31.5 CD cord-290297-efo9f7c5 24 13 % % NN cord-290297-efo9f7c5 24 14 ) ) -RRB- cord-290297-efo9f7c5 24 15 and and CC cord-290297-efo9f7c5 24 16 fungal fungal JJ cord-290297-efo9f7c5 24 17 ( ( -LRB- cord-290297-efo9f7c5 24 18 23.3 23.3 CD cord-290297-efo9f7c5 24 19 ) ) -RRB- cord-290297-efo9f7c5 24 20 infections infection NNS cord-290297-efo9f7c5 24 21 . . . cord-290297-efo9f7c5 25 1 Although although IN cord-290297-efo9f7c5 25 2 the the DT cord-290297-efo9f7c5 25 3 authors author NNS cord-290297-efo9f7c5 25 4 found find VBD cord-290297-efo9f7c5 25 5 no no DT cord-290297-efo9f7c5 25 6 significant significant JJ cord-290297-efo9f7c5 25 7 association association NN cord-290297-efo9f7c5 25 8 between between IN cord-290297-efo9f7c5 25 9 coinfection coinfection NN cord-290297-efo9f7c5 25 10 rates rate NNS cord-290297-efo9f7c5 25 11 and and CC cord-290297-efo9f7c5 25 12 outcome outcome NN cord-290297-efo9f7c5 25 13 severity severity NN cord-290297-efo9f7c5 25 14 or or CC cord-290297-efo9f7c5 25 15 mortality mortality NN cord-290297-efo9f7c5 25 16 , , , cord-290297-efo9f7c5 25 17 they -PRON- PRP cord-290297-efo9f7c5 25 18 described describe VBD cord-290297-efo9f7c5 25 19 interesting interesting JJ cord-290297-efo9f7c5 25 20 coinfection coinfection NN cord-290297-efo9f7c5 25 21 patterns pattern NNS cord-290297-efo9f7c5 25 22 in in IN cord-290297-efo9f7c5 25 23 different different JJ cord-290297-efo9f7c5 25 24 clinical clinical JJ cord-290297-efo9f7c5 25 25 groups group NNS cord-290297-efo9f7c5 25 26 ( ( -LRB- cord-290297-efo9f7c5 25 27 asymptom asymptom NNP cord-290297-efo9f7c5 25 28 - - HYPH cord-290297-efo9f7c5 25 29 atic atic JJ cord-290297-efo9f7c5 25 30 and and CC cord-290297-efo9f7c5 25 31 mildly mildly RB cord-290297-efo9f7c5 25 32 , , , cord-290297-efo9f7c5 25 33 moderately moderately RB cord-290297-efo9f7c5 25 34 , , , cord-290297-efo9f7c5 25 35 and and CC cord-290297-efo9f7c5 25 36 severely severely RB cord-290297-efo9f7c5 25 37 / / SYM cord-290297-efo9f7c5 25 38 critically critically RB cord-290297-efo9f7c5 25 39 ill ill JJ cord-290297-efo9f7c5 25 40 ) ) -RRB- cord-290297-efo9f7c5 25 41 . . . cord-290297-efo9f7c5 26 1 For for IN cord-290297-efo9f7c5 26 2 instance instance NN cord-290297-efo9f7c5 26 3 , , , cord-290297-efo9f7c5 26 4 Streptococcus streptococcus NN cord-290297-efo9f7c5 26 5 pneumoniae pneumoniae NN cord-290297-efo9f7c5 26 6 , , , cord-290297-efo9f7c5 26 7 Klebsiella Klebsiella NNP cord-290297-efo9f7c5 26 8 pneumoniae pneumoniae NN cord-290297-efo9f7c5 26 9 , , , cord-290297-efo9f7c5 26 10 Haemophilus haemophilus JJ cord-290297-efo9f7c5 26 11 influenzae influenzae NN cord-290297-efo9f7c5 26 12 , , , cord-290297-efo9f7c5 26 13 Escherichia escherichia NN cord-290297-efo9f7c5 26 14 coli coli NNS cord-290297-efo9f7c5 26 15 , , , cord-290297-efo9f7c5 26 16 Staphylococcus Staphylococcus NNP cord-290297-efo9f7c5 26 17 aureus aureus NN cord-290297-efo9f7c5 26 18 , , , cord-290297-efo9f7c5 26 19 Aspergillus aspergillus NN cord-290297-efo9f7c5 26 20 , , , cord-290297-efo9f7c5 26 21 and and CC cord-290297-efo9f7c5 26 22 Epstein Epstein NNP cord-290297-efo9f7c5 26 23 - - HYPH cord-290297-efo9f7c5 26 24 Barr Barr NNP cord-290297-efo9f7c5 26 25 ( ( -LRB- cord-290297-efo9f7c5 26 26 EB EB NNP cord-290297-efo9f7c5 26 27 ) ) -RRB- cord-290297-efo9f7c5 26 28 virus virus NN cord-290297-efo9f7c5 26 29 were be VBD cord-290297-efo9f7c5 26 30 detected detect VBN cord-290297-efo9f7c5 26 31 in in IN cord-290297-efo9f7c5 26 32 all all DT cord-290297-efo9f7c5 26 33 four four CD cord-290297-efo9f7c5 26 34 clinical clinical JJ cord-290297-efo9f7c5 26 35 groups group NNS cord-290297-efo9f7c5 26 36 , , , cord-290297-efo9f7c5 26 37 while while IN cord-290297-efo9f7c5 26 38 Pseudomonas Pseudomonas NNP cord-290297-efo9f7c5 26 39 aeruginosa aeruginosa NN cord-290297-efo9f7c5 26 40 , , , cord-290297-efo9f7c5 26 41 human human JJ cord-290297-efo9f7c5 26 42 adenovirus adenovirus NN cord-290297-efo9f7c5 26 43 , , , cord-290297-efo9f7c5 26 44 human human JJ cord-290297-efo9f7c5 26 45 rhinovirus rhinovirus NN cord-290297-efo9f7c5 26 46 , , , cord-290297-efo9f7c5 26 47 and and CC cord-290297-efo9f7c5 26 48 herpes herpes NN cord-290297-efo9f7c5 26 49 simplex simplex NNP cord-290297-efo9f7c5 26 50 virus virus NN cord-290297-efo9f7c5 26 51 were be VBD cord-290297-efo9f7c5 26 52 detected detect VBN cord-290297-efo9f7c5 26 53 only only RB cord-290297-efo9f7c5 26 54 in in IN cord-290297-efo9f7c5 26 55 symptomatic symptomatic JJ cord-290297-efo9f7c5 26 56 patients patient NNS cord-290297-efo9f7c5 26 57 regardless regardless RB cord-290297-efo9f7c5 26 58 of of IN cord-290297-efo9f7c5 26 59 disease disease NN cord-290297-efo9f7c5 26 60 severity severity NN cord-290297-efo9f7c5 26 61 . . . cord-290297-efo9f7c5 27 1 Interestingly interestingly RB cord-290297-efo9f7c5 27 2 , , , cord-290297-efo9f7c5 27 3 coinfections coinfection NNS cord-290297-efo9f7c5 27 4 with with IN cord-290297-efo9f7c5 27 5 influenza influenza NN cord-290297-efo9f7c5 27 6 A a DT cord-290297-efo9f7c5 27 7 virus virus NN cord-290297-efo9f7c5 27 8 , , , cord-290297-efo9f7c5 27 9 influenza influenza NN cord-290297-efo9f7c5 27 10 B b NN cord-290297-efo9f7c5 27 11 virus virus NN cord-290297-efo9f7c5 27 12 , , , cord-290297-efo9f7c5 27 13 or or CC cord-290297-efo9f7c5 27 14 coronavirus coronavirus NN cord-290297-efo9f7c5 27 15 were be VBD cord-290297-efo9f7c5 27 16 not not RB cord-290297-efo9f7c5 27 17 common common JJ cord-290297-efo9f7c5 27 18 in in IN cord-290297-efo9f7c5 27 19 these these DT cord-290297-efo9f7c5 27 20 COVID-19 covid-19 JJ cord-290297-efo9f7c5 27 21 patients patient NNS cord-290297-efo9f7c5 27 22 , , , cord-290297-efo9f7c5 27 23 though though IN cord-290297-efo9f7c5 27 24 samples sample NNS cord-290297-efo9f7c5 27 25 were be VBD cord-290297-efo9f7c5 27 26 collected collect VBN cord-290297-efo9f7c5 27 27 during during IN cord-290297-efo9f7c5 27 28 the the DT cord-290297-efo9f7c5 27 29 flu flu NN cord-290297-efo9f7c5 27 30 season season NN cord-290297-efo9f7c5 27 31 ( ( -LRB- cord-290297-efo9f7c5 27 32 4 4 CD cord-290297-efo9f7c5 27 33 ) ) -RRB- cord-290297-efo9f7c5 27 34 . . . cord-290297-efo9f7c5 28 1 Altogether altogether RB cord-290297-efo9f7c5 28 2 , , , cord-290297-efo9f7c5 28 3 these these DT cord-290297-efo9f7c5 28 4 early early JJ cord-290297-efo9f7c5 28 5 data datum NNS cord-290297-efo9f7c5 28 6 suggest suggest VBP cord-290297-efo9f7c5 28 7 that that IN cord-290297-efo9f7c5 28 8 the the DT cord-290297-efo9f7c5 28 9 specific specific JJ cord-290297-efo9f7c5 28 10 coinfecting coinfecte VBG cord-290297-efo9f7c5 28 11 pathogens pathogen NNS cord-290297-efo9f7c5 28 12 may may MD cord-290297-efo9f7c5 28 13 worsen worsen VB cord-290297-efo9f7c5 28 14 disease disease NN cord-290297-efo9f7c5 28 15 prognosis prognosis NN cord-290297-efo9f7c5 28 16 and and CC cord-290297-efo9f7c5 28 17 warrant warrant VB cord-290297-efo9f7c5 28 18 further further JJ cord-290297-efo9f7c5 28 19 investigation investigation NN cord-290297-efo9f7c5 28 20 . . . cord-290297-efo9f7c5 29 1 While while IN cord-290297-efo9f7c5 29 2 it -PRON- PRP cord-290297-efo9f7c5 29 3 is be VBZ cord-290297-efo9f7c5 29 4 unclear unclear JJ cord-290297-efo9f7c5 29 5 whether whether IN cord-290297-efo9f7c5 29 6 coinfections coinfection NNS cord-290297-efo9f7c5 29 7 definitively definitively RB cord-290297-efo9f7c5 29 8 worsen worsen VBP cord-290297-efo9f7c5 29 9 COVID-19 covid-19 JJ cord-290297-efo9f7c5 29 10 patient patient JJ cord-290297-efo9f7c5 29 11 outcomes outcome NNS cord-290297-efo9f7c5 29 12 , , , cord-290297-efo9f7c5 29 13 historical historical JJ cord-290297-efo9f7c5 29 14 data datum NNS cord-290297-efo9f7c5 29 15 from from IN cord-290297-efo9f7c5 29 16 pandemics pandemic NNS cord-290297-efo9f7c5 29 17 and and CC cord-290297-efo9f7c5 29 18 seasonal seasonal JJ cord-290297-efo9f7c5 29 19 flu flu NN cord-290297-efo9f7c5 29 20 suggest suggest VBP cord-290297-efo9f7c5 29 21 that that IN cord-290297-efo9f7c5 29 22 bacterial bacterial JJ cord-290297-efo9f7c5 29 23 coinfections coinfection NNS cord-290297-efo9f7c5 29 24 can can MD cord-290297-efo9f7c5 29 25 worsen worsen VB cord-290297-efo9f7c5 29 26 viral viral JJ cord-290297-efo9f7c5 29 27 diseases disease NNS cord-290297-efo9f7c5 29 28 ( ( -LRB- cord-290297-efo9f7c5 29 29 5 5 CD cord-290297-efo9f7c5 29 30 ) ) -RRB- cord-290297-efo9f7c5 29 31 ( ( -LRB- cord-290297-efo9f7c5 29 32 6 6 LS cord-290297-efo9f7c5 29 33 ) ) -RRB- cord-290297-efo9f7c5 29 34 ( ( -LRB- cord-290297-efo9f7c5 29 35 7 7 LS cord-290297-efo9f7c5 29 36 ) ) -RRB- cord-290297-efo9f7c5 29 37 ( ( -LRB- cord-290297-efo9f7c5 29 38 8) 8) NNP cord-290297-efo9f7c5 29 39 ( ( -LRB- cord-290297-efo9f7c5 29 40 9 9 CD cord-290297-efo9f7c5 29 41 ) ) -RRB- cord-290297-efo9f7c5 29 42 ( ( -LRB- cord-290297-efo9f7c5 29 43 10 10 CD cord-290297-efo9f7c5 29 44 ) ) -RRB- cord-290297-efo9f7c5 29 45 ( ( -LRB- cord-290297-efo9f7c5 29 46 11 11 CD cord-290297-efo9f7c5 29 47 ) ) -RRB- cord-290297-efo9f7c5 29 48 ( ( -LRB- cord-290297-efo9f7c5 29 49 12 12 CD cord-290297-efo9f7c5 29 50 ) ) -RRB- cord-290297-efo9f7c5 29 51 ( ( -LRB- cord-290297-efo9f7c5 29 52 13 13 CD cord-290297-efo9f7c5 29 53 ) ) -RRB- cord-290297-efo9f7c5 29 54 . . . cord-290297-efo9f7c5 30 1 During during IN cord-290297-efo9f7c5 30 2 the the DT cord-290297-efo9f7c5 30 3 first first JJ cord-290297-efo9f7c5 30 4 SARS SARS NNP cord-290297-efo9f7c5 30 5 - - HYPH cord-290297-efo9f7c5 30 6 CoV CoV NNP cord-290297-efo9f7c5 30 7 outbreak outbreak NN cord-290297-efo9f7c5 30 8 in in IN cord-290297-efo9f7c5 30 9 2003 2003 CD cord-290297-efo9f7c5 30 10 , , , cord-290297-efo9f7c5 30 11 up up IN cord-290297-efo9f7c5 30 12 to to TO cord-290297-efo9f7c5 30 13 30 30 CD cord-290297-efo9f7c5 30 14 % % NN cord-290297-efo9f7c5 30 15 of of IN cord-290297-efo9f7c5 30 16 patients patient NNS cord-290297-efo9f7c5 30 17 were be VBD cord-290297-efo9f7c5 30 18 diagnosed diagnose VBN cord-290297-efo9f7c5 30 19 with with IN cord-290297-efo9f7c5 30 20 secondary secondary JJ cord-290297-efo9f7c5 30 21 bacterial bacterial JJ cord-290297-efo9f7c5 30 22 infections infection NNS cord-290297-efo9f7c5 30 23 and and CC cord-290297-efo9f7c5 30 24 coinfection coinfection NN cord-290297-efo9f7c5 30 25 was be VBD cord-290297-efo9f7c5 30 26 positively positively RB cord-290297-efo9f7c5 30 27 associated associate VBN cord-290297-efo9f7c5 30 28 with with IN cord-290297-efo9f7c5 30 29 disease disease NN cord-290297-efo9f7c5 30 30 severity severity NN cord-290297-efo9f7c5 30 31 ( ( -LRB- cord-290297-efo9f7c5 30 32 5 5 CD cord-290297-efo9f7c5 30 33 , , , cord-290297-efo9f7c5 30 34 6 6 CD cord-290297-efo9f7c5 30 35 ) ) -RRB- cord-290297-efo9f7c5 30 36 . . . cord-290297-efo9f7c5 31 1 Bacterial bacterial JJ cord-290297-efo9f7c5 31 2 coinfections coinfection NNS cord-290297-efo9f7c5 31 3 are be VBP cord-290297-efo9f7c5 31 4 also also RB cord-290297-efo9f7c5 31 5 present present JJ cord-290297-efo9f7c5 31 6 during during IN cord-290297-efo9f7c5 31 7 regular regular JJ cord-290297-efo9f7c5 31 8 influenza influenza NN cord-290297-efo9f7c5 31 9 seasons season NNS cord-290297-efo9f7c5 31 10 in in IN cord-290297-efo9f7c5 31 11 2 2 CD cord-290297-efo9f7c5 31 12 % % NN cord-290297-efo9f7c5 31 13 to to TO cord-290297-efo9f7c5 31 14 65 65 CD cord-290297-efo9f7c5 31 15 % % NN cord-290297-efo9f7c5 31 16 of of IN cord-290297-efo9f7c5 31 17 cases case NNS cord-290297-efo9f7c5 31 18 and and CC cord-290297-efo9f7c5 31 19 are be VBP cord-290297-efo9f7c5 31 20 associated associate VBN cord-290297-efo9f7c5 31 21 with with IN cord-290297-efo9f7c5 31 22 morbidity morbidity NN cord-290297-efo9f7c5 31 23 and and CC cord-290297-efo9f7c5 31 24 mortality mortality NN cord-290297-efo9f7c5 31 25 ( ( -LRB- cord-290297-efo9f7c5 31 26 7 7 CD cord-290297-efo9f7c5 31 27 ) ) -RRB- cord-290297-efo9f7c5 31 28 ( ( -LRB- cord-290297-efo9f7c5 31 29 8) 8) NNP cord-290297-efo9f7c5 31 30 ( ( -LRB- cord-290297-efo9f7c5 31 31 9 9 LS cord-290297-efo9f7c5 31 32 ) ) -RRB- cord-290297-efo9f7c5 31 33 We -PRON- PRP cord-290297-efo9f7c5 31 34 are be VBP cord-290297-efo9f7c5 31 35 using use VBG cord-290297-efo9f7c5 31 36 more more JJR cord-290297-efo9f7c5 31 37 antibiotics antibiotic NNS cord-290297-efo9f7c5 31 38 in in IN cord-290297-efo9f7c5 31 39 our -PRON- PRP$ cord-290297-efo9f7c5 31 40 fight fight NN cord-290297-efo9f7c5 31 41 to to TO cord-290297-efo9f7c5 31 42 save save VB cord-290297-efo9f7c5 31 43 COVID-19 covid-19 JJ cord-290297-efo9f7c5 31 44 patients patient NNS cord-290297-efo9f7c5 31 45 from from IN cord-290297-efo9f7c5 31 46 bacterial bacterial JJ cord-290297-efo9f7c5 31 47 coinfections coinfection NNS cord-290297-efo9f7c5 31 48 , , , cord-290297-efo9f7c5 31 49 and and CC cord-290297-efo9f7c5 31 50 it -PRON- PRP cord-290297-efo9f7c5 31 51 is be VBZ cord-290297-efo9f7c5 31 52 important important JJ cord-290297-efo9f7c5 31 53 to to TO cord-290297-efo9f7c5 31 54 consider consider VB cord-290297-efo9f7c5 31 55 how how WRB cord-290297-efo9f7c5 31 56 this this DT cord-290297-efo9f7c5 31 57 could could MD cord-290297-efo9f7c5 31 58 affect affect VB cord-290297-efo9f7c5 31 59 the the DT cord-290297-efo9f7c5 31 60 prevalence prevalence NN cord-290297-efo9f7c5 31 61 of of IN cord-290297-efo9f7c5 31 62 antibiotic antibiotic JJ cord-290297-efo9f7c5 31 63 - - HYPH cord-290297-efo9f7c5 31 64 resistant resistant JJ cord-290297-efo9f7c5 31 65 bacteria bacteria NNS cord-290297-efo9f7c5 31 66 globally globally RB cord-290297-efo9f7c5 31 67 . . . cord-290297-efo9f7c5 32 1 During during IN cord-290297-efo9f7c5 32 2 the the DT cord-290297-efo9f7c5 32 3 first first JJ cord-290297-efo9f7c5 32 4 SARS SARS NNP cord-290297-efo9f7c5 32 5 - - HYPH cord-290297-efo9f7c5 32 6 CoV CoV NNP cord-290297-efo9f7c5 32 7 outbreak outbreak NN cord-290297-efo9f7c5 32 8 , , , cord-290297-efo9f7c5 32 9 analyses analysis NNS cord-290297-efo9f7c5 32 10 of of IN cord-290297-efo9f7c5 32 11 isolates isolate NNS cord-290297-efo9f7c5 32 12 collected collect VBN cord-290297-efo9f7c5 32 13 from from IN cord-290297-efo9f7c5 32 14 patients patient NNS cord-290297-efo9f7c5 32 15 in in IN cord-290297-efo9f7c5 32 16 the the DT cord-290297-efo9f7c5 32 17 intensive intensive JJ cord-290297-efo9f7c5 32 18 care care NN cord-290297-efo9f7c5 32 19 unit unit NN cord-290297-efo9f7c5 32 20 ( ( -LRB- cord-290297-efo9f7c5 32 21 ICU ICU NNP cord-290297-efo9f7c5 32 22 ) ) -RRB- cord-290297-efo9f7c5 32 23 in in IN cord-290297-efo9f7c5 32 24 Prince Prince NNP cord-290297-efo9f7c5 32 25 of of IN cord-290297-efo9f7c5 32 26 Wales Wales NNP cord-290297-efo9f7c5 32 27 Hospital Hospital NNP cord-290297-efo9f7c5 32 28 ( ( -LRB- cord-290297-efo9f7c5 32 29 Hong Hong NNP cord-290297-efo9f7c5 32 30 Kong Kong NNP cord-290297-efo9f7c5 32 31 ) ) -RRB- cord-290297-efo9f7c5 32 32 from from IN cord-290297-efo9f7c5 32 33 12 12 CD cord-290297-efo9f7c5 32 34 March March NNP cord-290297-efo9f7c5 32 35 to to IN cord-290297-efo9f7c5 32 36 31 31 CD cord-290297-efo9f7c5 32 37 May May NNP cord-290297-efo9f7c5 32 38 2003 2003 CD cord-290297-efo9f7c5 32 39 showed show VBD cord-290297-efo9f7c5 32 40 that that IN cord-290297-efo9f7c5 32 41 rates rate NNS cord-290297-efo9f7c5 32 42 of of IN cord-290297-efo9f7c5 32 43 methicillinresistant methicillinresistant JJ cord-290297-efo9f7c5 32 44 S. S. NNP cord-290297-efo9f7c5 32 45 aureus aureus NN cord-290297-efo9f7c5 32 46 acquisition acquisition NN cord-290297-efo9f7c5 32 47 drastically drastically RB cord-290297-efo9f7c5 32 48 increased increase VBD cord-290297-efo9f7c5 32 49 during during IN cord-290297-efo9f7c5 32 50 the the DT cord-290297-efo9f7c5 32 51 outbreak outbreak NN cord-290297-efo9f7c5 32 52 from from IN cord-290297-efo9f7c5 32 53 3.53 3.53 CD cord-290297-efo9f7c5 32 54 % % NN cord-290297-efo9f7c5 32 55 pre pre JJ cord-290297-efo9f7c5 32 56 - - NNP cord-290297-efo9f7c5 32 57 SARS SARS NNP cord-290297-efo9f7c5 32 58 to to IN cord-290297-efo9f7c5 32 59 25.30 25.30 CD cord-290297-efo9f7c5 32 60 % % NN cord-290297-efo9f7c5 32 61 during during IN cord-290297-efo9f7c5 32 62 the the DT cord-290297-efo9f7c5 32 63 SARS SARS NNP cord-290297-efo9f7c5 32 64 outbreak outbreak NN cord-290297-efo9f7c5 32 65 , , , cord-290297-efo9f7c5 32 66 despite despite IN cord-290297-efo9f7c5 32 67 extensive extensive JJ cord-290297-efo9f7c5 32 68 infection infection NN cord-290297-efo9f7c5 32 69 control control NN cord-290297-efo9f7c5 32 70 precautions precaution NNS cord-290297-efo9f7c5 32 71 ( ( -LRB- cord-290297-efo9f7c5 32 72 10 10 CD cord-290297-efo9f7c5 32 73 ) ) -RRB- cord-290297-efo9f7c5 32 74 . . . cord-290297-efo9f7c5 33 1 Other other JJ cord-290297-efo9f7c5 33 2 pathogens pathogen NNS cord-290297-efo9f7c5 33 3 were be VBD cord-290297-efo9f7c5 33 4 found find VBN cord-290297-efo9f7c5 33 5 in in IN cord-290297-efo9f7c5 33 6 postmortem postmortem JJ cord-290297-efo9f7c5 33 7 lung lung NN cord-290297-efo9f7c5 33 8 specimens specimen NNS cord-290297-efo9f7c5 33 9 of of IN cord-290297-efo9f7c5 33 10 patients patient NNS cord-290297-efo9f7c5 33 11 from from IN cord-290297-efo9f7c5 33 12 Hong Hong NNP cord-290297-efo9f7c5 33 13 Kong Kong NNP cord-290297-efo9f7c5 33 14 and and CC cord-290297-efo9f7c5 33 15 Singapore Singapore NNP cord-290297-efo9f7c5 33 16 , , , cord-290297-efo9f7c5 33 17 including include VBG cord-290297-efo9f7c5 33 18 S. S. NNP cord-290297-efo9f7c5 33 19 aureus aureus NN cord-290297-efo9f7c5 33 20 , , , cord-290297-efo9f7c5 33 21 P. P. NNP cord-290297-efo9f7c5 33 22 aeruginosa aeruginosa NN cord-290297-efo9f7c5 33 23 , , , cord-290297-efo9f7c5 33 24 Klebsiella Klebsiella NNP cord-290297-efo9f7c5 33 25 spp spp NNS cord-290297-efo9f7c5 33 26 . . . cord-290297-efo9f7c5 34 1 , , , cord-290297-efo9f7c5 34 2 and and CC cord-290297-efo9f7c5 34 3 S. S. NNP cord-290297-efo9f7c5 34 4 pneumoniae pneumoniae NN cord-290297-efo9f7c5 34 5 , , , cord-290297-efo9f7c5 34 6 all all DT cord-290297-efo9f7c5 34 7 of of IN cord-290297-efo9f7c5 34 8 which which WDT cord-290297-efo9f7c5 34 9 are be VBP cord-290297-efo9f7c5 34 10 well well RB cord-290297-efo9f7c5 34 11 known know VBN cord-290297-efo9f7c5 34 12 for for IN cord-290297-efo9f7c5 34 13 their -PRON- PRP$ cord-290297-efo9f7c5 34 14 high high JJ cord-290297-efo9f7c5 34 15 resistance resistance NN cord-290297-efo9f7c5 34 16 to to IN cord-290297-efo9f7c5 34 17 a a DT cord-290297-efo9f7c5 34 18 broad broad JJ cord-290297-efo9f7c5 34 19 spectrum spectrum NN cord-290297-efo9f7c5 34 20 of of IN cord-290297-efo9f7c5 34 21 drugs drug NNS cord-290297-efo9f7c5 34 22 ( ( -LRB- cord-290297-efo9f7c5 34 23 14 14 CD cord-290297-efo9f7c5 34 24 , , , cord-290297-efo9f7c5 34 25 15 15 CD cord-290297-efo9f7c5 34 26 ) ) -RRB- cord-290297-efo9f7c5 34 27 . . . cord-290297-efo9f7c5 35 1 It -PRON- PRP cord-290297-efo9f7c5 35 2 is be VBZ cord-290297-efo9f7c5 35 3 not not RB cord-290297-efo9f7c5 35 4 clear clear JJ cord-290297-efo9f7c5 35 5 whether whether IN cord-290297-efo9f7c5 35 6 the the DT cord-290297-efo9f7c5 35 7 COVID-19 covid-19 JJ cord-290297-efo9f7c5 35 8 outbreak outbreak NN cord-290297-efo9f7c5 35 9 will will MD cord-290297-efo9f7c5 35 10 lead lead VB cord-290297-efo9f7c5 35 11 to to IN cord-290297-efo9f7c5 35 12 increased increase VBN cord-290297-efo9f7c5 35 13 rates rate NNS cord-290297-efo9f7c5 35 14 of of IN cord-290297-efo9f7c5 35 15 antibiotic antibiotic JJ cord-290297-efo9f7c5 35 16 - - HYPH cord-290297-efo9f7c5 35 17 resistant resistant JJ cord-290297-efo9f7c5 35 18 bacteria bacteria NNS cord-290297-efo9f7c5 35 19 since since IN cord-290297-efo9f7c5 35 20 the the DT cord-290297-efo9f7c5 35 21 use use NN cord-290297-efo9f7c5 35 22 of of IN cord-290297-efo9f7c5 35 23 antibiotics antibiotic NNS cord-290297-efo9f7c5 35 24 does do VBZ cord-290297-efo9f7c5 35 25 not not RB cord-290297-efo9f7c5 35 26 always always RB cord-290297-efo9f7c5 35 27 result result VB cord-290297-efo9f7c5 35 28 in in IN cord-290297-efo9f7c5 35 29 increased increase VBN cord-290297-efo9f7c5 35 30 rates rate NNS cord-290297-efo9f7c5 35 31 of of IN cord-290297-efo9f7c5 35 32 drug drug NN cord-290297-efo9f7c5 35 33 - - HYPH cord-290297-efo9f7c5 35 34 resistant resistant JJ cord-290297-efo9f7c5 35 35 strains strain NNS cord-290297-efo9f7c5 35 36 ( ( -LRB- cord-290297-efo9f7c5 35 37 16 16 CD cord-290297-efo9f7c5 35 38 ) ) -RRB- cord-290297-efo9f7c5 35 39 , , , cord-290297-efo9f7c5 35 40 yet yet CC cord-290297-efo9f7c5 35 41 it -PRON- PRP cord-290297-efo9f7c5 35 42 will will MD cord-290297-efo9f7c5 35 43 be be VB cord-290297-efo9f7c5 35 44 important important JJ cord-290297-efo9f7c5 35 45 to to TO cord-290297-efo9f7c5 35 46 continue continue VB cord-290297-efo9f7c5 35 47 monitoring monitor VBG cord-290297-efo9f7c5 35 48 rates rate NNS cord-290297-efo9f7c5 35 49 of of IN cord-290297-efo9f7c5 35 50 antibiotic antibiotic JJ cord-290297-efo9f7c5 35 51 - - HYPH cord-290297-efo9f7c5 35 52 resistant resistant JJ cord-290297-efo9f7c5 35 53 bacterial bacterial JJ cord-290297-efo9f7c5 35 54 infections infection NNS cord-290297-efo9f7c5 35 55 . . . cord-290297-efo9f7c5 36 1 These these DT cord-290297-efo9f7c5 36 2 data datum NNS cord-290297-efo9f7c5 36 3 from from IN cord-290297-efo9f7c5 36 4 the the DT cord-290297-efo9f7c5 36 5 current current JJ cord-290297-efo9f7c5 36 6 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 36 7 pandemic pandemic NN cord-290297-efo9f7c5 36 8 , , , cord-290297-efo9f7c5 36 9 previous previous JJ cord-290297-efo9f7c5 36 10 pandemics pandemic NNS cord-290297-efo9f7c5 36 11 , , , cord-290297-efo9f7c5 36 12 and and CC cord-290297-efo9f7c5 36 13 seasonal seasonal JJ cord-290297-efo9f7c5 36 14 influenza influenza NN cord-290297-efo9f7c5 36 15 raise raise VB cord-290297-efo9f7c5 36 16 important important JJ cord-290297-efo9f7c5 36 17 questions question NNS cord-290297-efo9f7c5 36 18 that that WDT cord-290297-efo9f7c5 36 19 need need VBP cord-290297-efo9f7c5 36 20 to to TO cord-290297-efo9f7c5 36 21 be be VB cord-290297-efo9f7c5 36 22 investigated investigate VBN cord-290297-efo9f7c5 36 23 . . . cord-290297-efo9f7c5 37 1 First first RB cord-290297-efo9f7c5 37 2 , , , cord-290297-efo9f7c5 37 3 are be VBP cord-290297-efo9f7c5 37 4 there there EX cord-290297-efo9f7c5 37 5 synergic synergic JJ cord-290297-efo9f7c5 37 6 interactions interaction NNS cord-290297-efo9f7c5 37 7 between between IN cord-290297-efo9f7c5 37 8 the the DT cord-290297-efo9f7c5 37 9 SARS SARS NNP cord-290297-efo9f7c5 37 10 - - HYPH cord-290297-efo9f7c5 37 11 CoV-2 CoV-2 NNP cord-290297-efo9f7c5 37 12 virus virus NN cord-290297-efo9f7c5 37 13 and and CC cord-290297-efo9f7c5 37 14 certain certain JJ cord-290297-efo9f7c5 37 15 coinfecting coinfecte VBG cord-290297-efo9f7c5 37 16 bacteria bacteria NNS cord-290297-efo9f7c5 37 17 ? ? . cord-290297-efo9f7c5 38 1 Second second RB cord-290297-efo9f7c5 38 2 , , , cord-290297-efo9f7c5 38 3 does do VBZ cord-290297-efo9f7c5 38 4 coinfection coinfection NN cord-290297-efo9f7c5 38 5 with with IN cord-290297-efo9f7c5 38 6 antibiotic antibiotic JJ cord-290297-efo9f7c5 38 7 - - HYPH cord-290297-efo9f7c5 38 8 resistant resistant JJ cord-290297-efo9f7c5 38 9 bacteria bacteria NNS cord-290297-efo9f7c5 38 10 affect affect VBP cord-290297-efo9f7c5 38 11 disease disease NN cord-290297-efo9f7c5 38 12 severity severity NN cord-290297-efo9f7c5 38 13 ? ? . cord-290297-efo9f7c5 39 1 Indeed indeed RB cord-290297-efo9f7c5 39 2 , , , cord-290297-efo9f7c5 39 3 some some DT cord-290297-efo9f7c5 39 4 of of IN cord-290297-efo9f7c5 39 5 the the DT cord-290297-efo9f7c5 39 6 pathogens pathogen NNS cord-290297-efo9f7c5 39 7 detected detect VBN cord-290297-efo9f7c5 39 8 in in IN cord-290297-efo9f7c5 39 9 COVID-19 covid-19 JJ cord-290297-efo9f7c5 39 10 patients patient NNS cord-290297-efo9f7c5 39 11 can can MD cord-290297-efo9f7c5 39 12 be be VB cord-290297-efo9f7c5 39 13 antibiotic antibiotic JJ cord-290297-efo9f7c5 39 14 resistant resistant JJ cord-290297-efo9f7c5 39 15 , , , cord-290297-efo9f7c5 39 16 which which WDT cord-290297-efo9f7c5 39 17 could could MD cord-290297-efo9f7c5 39 18 reduce reduce VB cord-290297-efo9f7c5 39 19 the the DT cord-290297-efo9f7c5 39 20 efficacy efficacy NN cord-290297-efo9f7c5 39 21 of of IN cord-290297-efo9f7c5 39 22 treatments treatment NNS cord-290297-efo9f7c5 39 23 administered administer VBN cord-290297-efo9f7c5 39 24 to to IN cord-290297-efo9f7c5 39 25 patients patient NNS cord-290297-efo9f7c5 39 26 . . . cord-290297-efo9f7c5 40 1 Unfortunately unfortunately RB cord-290297-efo9f7c5 40 2 , , , cord-290297-efo9f7c5 40 3 in in IN cord-290297-efo9f7c5 40 4 the the DT cord-290297-efo9f7c5 40 5 first first JJ cord-290297-efo9f7c5 40 6 two two CD cord-290297-efo9f7c5 40 7 studies study NNS cord-290297-efo9f7c5 40 8 , , , cord-290297-efo9f7c5 40 9 where where WRB cord-290297-efo9f7c5 40 10 coinfections coinfection NNS cord-290297-efo9f7c5 40 11 were be VBD cord-290297-efo9f7c5 40 12 associated associate VBN cord-290297-efo9f7c5 40 13 with with IN cord-290297-efo9f7c5 40 14 worse bad JJR cord-290297-efo9f7c5 40 15 outcomes outcome NNS cord-290297-efo9f7c5 40 16 ( ( -LRB- cord-290297-efo9f7c5 40 17 2 2 CD cord-290297-efo9f7c5 40 18 , , , cord-290297-efo9f7c5 40 19 3 3 CD cord-290297-efo9f7c5 40 20 ) ) -RRB- cord-290297-efo9f7c5 40 21 , , , cord-290297-efo9f7c5 40 22 the the DT cord-290297-efo9f7c5 40 23 specific specific JJ cord-290297-efo9f7c5 40 24 coinfecting coinfecte VBG cord-290297-efo9f7c5 40 25 pathogens pathogen NNS cord-290297-efo9f7c5 40 26 detected detect VBN cord-290297-efo9f7c5 40 27 were be VBD cord-290297-efo9f7c5 40 28 not not RB cord-290297-efo9f7c5 40 29 described describe VBN cord-290297-efo9f7c5 40 30 and and CC cord-290297-efo9f7c5 40 31 no no DT cord-290297-efo9f7c5 40 32 studies study NNS cord-290297-efo9f7c5 40 33 thus thus RB cord-290297-efo9f7c5 40 34 far far RB cord-290297-efo9f7c5 40 35 have have VBP cord-290297-efo9f7c5 40 36 analyzed analyze VBN cord-290297-efo9f7c5 40 37 rates rate NNS cord-290297-efo9f7c5 40 38 of of IN cord-290297-efo9f7c5 40 39 coinfection coinfection NN cord-290297-efo9f7c5 40 40 by by IN cord-290297-efo9f7c5 40 41 antibiotic antibiotic JJ cord-290297-efo9f7c5 40 42 - - HYPH cord-290297-efo9f7c5 40 43 resistant resistant JJ cord-290297-efo9f7c5 40 44 bacteria bacteria NNS cord-290297-efo9f7c5 40 45 . . . cord-290297-efo9f7c5 41 1 Thus thus RB cord-290297-efo9f7c5 41 2 , , , cord-290297-efo9f7c5 41 3 it -PRON- PRP cord-290297-efo9f7c5 41 4 is be VBZ cord-290297-efo9f7c5 41 5 impossible impossible JJ cord-290297-efo9f7c5 41 6 to to TO cord-290297-efo9f7c5 41 7 determine determine VB cord-290297-efo9f7c5 41 8 from from IN cord-290297-efo9f7c5 41 9 the the DT cord-290297-efo9f7c5 41 10 available available JJ cord-290297-efo9f7c5 41 11 data datum NNS cord-290297-efo9f7c5 41 12 whether whether IN cord-290297-efo9f7c5 41 13 certain certain JJ cord-290297-efo9f7c5 41 14 bacterial bacterial JJ cord-290297-efo9f7c5 41 15 species specie NNS cord-290297-efo9f7c5 41 16 or or CC cord-290297-efo9f7c5 41 17 whether whether IN cord-290297-efo9f7c5 41 18 antibiotic antibiotic JJ cord-290297-efo9f7c5 41 19 - - HYPH cord-290297-efo9f7c5 41 20 resistant resistant JJ cord-290297-efo9f7c5 41 21 strains strain NNS cord-290297-efo9f7c5 41 22 correlate correlate VBP cord-290297-efo9f7c5 41 23 with with IN cord-290297-efo9f7c5 41 24 outcome outcome NN cord-290297-efo9f7c5 41 25 severity severity NN cord-290297-efo9f7c5 41 26 or or CC cord-290297-efo9f7c5 41 27 mortality mortality NN cord-290297-efo9f7c5 41 28 . . . cord-290297-efo9f7c5 42 1 However however RB cord-290297-efo9f7c5 42 2 , , , cord-290297-efo9f7c5 42 3 the the DT cord-290297-efo9f7c5 42 4 presence presence NN cord-290297-efo9f7c5 42 5 of of IN cord-290297-efo9f7c5 42 6 antibiotic antibiotic JJ cord-290297-efo9f7c5 42 7 - - HYPH cord-290297-efo9f7c5 42 8 resistant resistant JJ cord-290297-efo9f7c5 42 9 bacteria bacteria NNS cord-290297-efo9f7c5 42 10 could could MD cord-290297-efo9f7c5 42 11 potentially potentially RB cord-290297-efo9f7c5 42 12 explain explain VB cord-290297-efo9f7c5 42 13 the the DT cord-290297-efo9f7c5 42 14 high high JJ cord-290297-efo9f7c5 42 15 rates rate NNS cord-290297-efo9f7c5 42 16 of of IN cord-290297-efo9f7c5 42 17 bacterial bacterial JJ cord-290297-efo9f7c5 42 18 coinfections coinfection NNS cord-290297-efo9f7c5 42 19 in in IN cord-290297-efo9f7c5 42 20 critically critically RB cord-290297-efo9f7c5 42 21 ill ill JJ cord-290297-efo9f7c5 42 22 patients patient NNS cord-290297-efo9f7c5 42 23 despite despite IN cord-290297-efo9f7c5 42 24 extensive extensive JJ cord-290297-efo9f7c5 42 25 antibiotic antibiotic JJ cord-290297-efo9f7c5 42 26 treatments treatment NNS cord-290297-efo9f7c5 42 27 in in IN cord-290297-efo9f7c5 42 28 these these DT cord-290297-efo9f7c5 42 29 cohorts cohort NNS cord-290297-efo9f7c5 42 30 . . . cord-290297-efo9f7c5 43 1 Finally finally RB cord-290297-efo9f7c5 43 2 , , , cord-290297-efo9f7c5 43 3 the the DT cord-290297-efo9f7c5 43 4 battle battle NN cord-290297-efo9f7c5 43 5 with with IN cord-290297-efo9f7c5 43 6 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 43 7 may may MD cord-290297-efo9f7c5 43 8 accelerate accelerate VB cord-290297-efo9f7c5 43 9 the the DT cord-290297-efo9f7c5 43 10 worsening worsening NN cord-290297-efo9f7c5 43 11 of of IN cord-290297-efo9f7c5 43 12 our -PRON- PRP$ cord-290297-efo9f7c5 43 13 already already RB cord-290297-efo9f7c5 43 14 dire dire JJ cord-290297-efo9f7c5 43 15 situation situation NN cord-290297-efo9f7c5 43 16 with with IN cord-290297-efo9f7c5 43 17 respect respect NN cord-290297-efo9f7c5 43 18 to to IN cord-290297-efo9f7c5 43 19 antibiotic antibiotic JJ cord-290297-efo9f7c5 43 20 - - HYPH cord-290297-efo9f7c5 43 21 resistant resistant JJ cord-290297-efo9f7c5 43 22 pathogens pathogen NNS cord-290297-efo9f7c5 43 23 . . . cord-290297-efo9f7c5 44 1 The the DT cord-290297-efo9f7c5 44 2 rising rise VBG cord-290297-efo9f7c5 44 3 number number NN cord-290297-efo9f7c5 44 4 of of IN cord-290297-efo9f7c5 44 5 multidrug multidrug NN cord-290297-efo9f7c5 44 6 - - HYPH cord-290297-efo9f7c5 44 7 resistant resistant JJ cord-290297-efo9f7c5 44 8 bacteria bacteria NNS cord-290297-efo9f7c5 44 9 and and CC cord-290297-efo9f7c5 44 10 our -PRON- PRP$ cord-290297-efo9f7c5 44 11 decreasing decrease VBG cord-290297-efo9f7c5 44 12 capacity capacity NN cord-290297-efo9f7c5 44 13 to to TO cord-290297-efo9f7c5 44 14 eradicate eradicate VB cord-290297-efo9f7c5 44 15 them -PRON- PRP cord-290297-efo9f7c5 44 16 not not RB cord-290297-efo9f7c5 44 17 only only RB cord-290297-efo9f7c5 44 18 render render VB cord-290297-efo9f7c5 44 19 us -PRON- PRP cord-290297-efo9f7c5 44 20 more more RBR cord-290297-efo9f7c5 44 21 vulnerable vulnerable JJ cord-290297-efo9f7c5 44 22 to to IN cord-290297-efo9f7c5 44 23 bacterial bacterial JJ cord-290297-efo9f7c5 44 24 infections infection NNS cord-290297-efo9f7c5 44 25 but but CC cord-290297-efo9f7c5 44 26 also also RB cord-290297-efo9f7c5 44 27 weaken weaken VB cord-290297-efo9f7c5 44 28 us -PRON- PRP cord-290297-efo9f7c5 44 29 during during IN cord-290297-efo9f7c5 44 30 viral viral JJ cord-290297-efo9f7c5 44 31 pandemics pandemic NNS cord-290297-efo9f7c5 44 32 . . . cord-290297-efo9f7c5 45 1 To to TO cord-290297-efo9f7c5 45 2 tackle tackle VB cord-290297-efo9f7c5 45 3 this this DT cord-290297-efo9f7c5 45 4 serious serious JJ cord-290297-efo9f7c5 45 5 issue issue NN cord-290297-efo9f7c5 45 6 , , , cord-290297-efo9f7c5 45 7 we -PRON- PRP cord-290297-efo9f7c5 45 8 urgently urgently RB cord-290297-efo9f7c5 45 9 need need VBP cord-290297-efo9f7c5 45 10 to to TO cord-290297-efo9f7c5 45 11 investigate investigate VB cord-290297-efo9f7c5 45 12 the the DT cord-290297-efo9f7c5 45 13 effects effect NNS cord-290297-efo9f7c5 45 14 of of IN cord-290297-efo9f7c5 45 15 bacterial bacterial JJ cord-290297-efo9f7c5 45 16 coinfections coinfection NNS cord-290297-efo9f7c5 45 17 during during IN cord-290297-efo9f7c5 45 18 viral viral JJ cord-290297-efo9f7c5 45 19 infections infection NNS cord-290297-efo9f7c5 45 20 and and CC cord-290297-efo9f7c5 45 21 find find VB cord-290297-efo9f7c5 45 22 new new JJ cord-290297-efo9f7c5 45 23 antimicrobial antimicrobial JJ cord-290297-efo9f7c5 45 24 compounds compound NNS cord-290297-efo9f7c5 45 25 to to TO cord-290297-efo9f7c5 45 26 eradicate eradicate VB cord-290297-efo9f7c5 45 27 multidrug multidrug NN cord-290297-efo9f7c5 45 28 - - HYPH cord-290297-efo9f7c5 45 29 resistant resistant JJ cord-290297-efo9f7c5 45 30 pathogens pathogen NNS cord-290297-efo9f7c5 45 31 . . . cord-290297-efo9f7c5 46 1 WHO who WP cord-290297-efo9f7c5 46 2 . . . cord-290297-efo9f7c5 47 1 2020 2020 CD cord-290297-efo9f7c5 47 2 . . . cord-290297-efo9f7c5 48 1 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 48 2 situation situation NN cord-290297-efo9f7c5 48 3 reports report VBZ cord-290297-efo9f7c5 48 4 COVID-19 covid-19 VBP cord-290297-efo9f7c5 48 5 with with IN cord-290297-efo9f7c5 48 6 different different JJ cord-290297-efo9f7c5 48 7 severities severity NNS cord-290297-efo9f7c5 48 8 : : : cord-290297-efo9f7c5 48 9 a a DT cord-290297-efo9f7c5 48 10 multi multi JJ cord-290297-efo9f7c5 48 11 - - JJ cord-290297-efo9f7c5 48 12 center center JJ cord-290297-efo9f7c5 48 13 study study NN cord-290297-efo9f7c5 48 14 of of IN cord-290297-efo9f7c5 48 15 clinical clinical JJ cord-290297-efo9f7c5 48 16 features feature NNS cord-290297-efo9f7c5 48 17 Clinical clinical JJ cord-290297-efo9f7c5 48 18 course course NN cord-290297-efo9f7c5 48 19 and and CC cord-290297-efo9f7c5 48 20 risk risk NN cord-290297-efo9f7c5 48 21 factors factor NNS cord-290297-efo9f7c5 48 22 for for IN cord-290297-efo9f7c5 48 23 mortality mortality NN cord-290297-efo9f7c5 48 24 of of IN cord-290297-efo9f7c5 48 25 adult adult NN cord-290297-efo9f7c5 48 26 inpatients inpatient NNS cord-290297-efo9f7c5 48 27 with with IN cord-290297-efo9f7c5 48 28 COVID-19 COVID-19 NNP cord-290297-efo9f7c5 48 29 in in IN cord-290297-efo9f7c5 48 30 Wuhan Wuhan NNP cord-290297-efo9f7c5 48 31 , , , cord-290297-efo9f7c5 48 32 China China NNP cord-290297-efo9f7c5 48 33 : : : cord-290297-efo9f7c5 49 1 a a DT cord-290297-efo9f7c5 49 2 retrospective retrospective JJ cord-290297-efo9f7c5 49 3 cohort cohort NN cord-290297-efo9f7c5 49 4 study study NN cord-290297-efo9f7c5 49 5 Co co NN cord-290297-efo9f7c5 49 6 - - NN cord-290297-efo9f7c5 49 7 infection infection NN cord-290297-efo9f7c5 49 8 with with IN cord-290297-efo9f7c5 49 9 respiratory respiratory JJ cord-290297-efo9f7c5 49 10 pathogens pathogen NNS cord-290297-efo9f7c5 49 11 among among IN cord-290297-efo9f7c5 49 12 COVID-2019 COVID-2019 NNP cord-290297-efo9f7c5 49 13 cases case NNS cord-290297-efo9f7c5 50 1 Risk risk NN cord-290297-efo9f7c5 50 2 of of IN cord-290297-efo9f7c5 50 3 ruling rule VBG cord-290297-efo9f7c5 50 4 out out RP cord-290297-efo9f7c5 50 5 severe severe JJ cord-290297-efo9f7c5 50 6 acute acute JJ cord-290297-efo9f7c5 50 7 respiratory respiratory JJ cord-290297-efo9f7c5 50 8 syndrome syndrome NN cord-290297-efo9f7c5 50 9 by by IN cord-290297-efo9f7c5 50 10 ruling rule VBG cord-290297-efo9f7c5 50 11 in in IN cord-290297-efo9f7c5 50 12 another another DT cord-290297-efo9f7c5 50 13 diagnosis diagnosis NN cord-290297-efo9f7c5 50 14 : : : cord-290297-efo9f7c5 50 15 variable variable JJ cord-290297-efo9f7c5 50 16 incidence incidence NN cord-290297-efo9f7c5 50 17 of of IN cord-290297-efo9f7c5 50 18 atypical atypical JJ cord-290297-efo9f7c5 50 19 bacteria bacteria NNS cord-290297-efo9f7c5 50 20 coinfection coinfection NN cord-290297-efo9f7c5 50 21 based base VBN cord-290297-efo9f7c5 50 22 on on IN cord-290297-efo9f7c5 50 23 diagnostic diagnostic JJ cord-290297-efo9f7c5 50 24 assays assay NNS cord-290297-efo9f7c5 51 1 A a DT cord-290297-efo9f7c5 51 2 major major JJ cord-290297-efo9f7c5 51 3 outbreak outbreak NN cord-290297-efo9f7c5 51 4 of of IN cord-290297-efo9f7c5 51 5 severe severe JJ cord-290297-efo9f7c5 51 6 acute acute JJ cord-290297-efo9f7c5 51 7 respiratory respiratory JJ cord-290297-efo9f7c5 51 8 syndrome syndrome NN cord-290297-efo9f7c5 51 9 in in IN cord-290297-efo9f7c5 51 10 Hong Hong NNP cord-290297-efo9f7c5 51 11 Kong Kong NNP cord-290297-efo9f7c5 51 12 Bacterial bacterial JJ cord-290297-efo9f7c5 51 13 coinfection coinfection NN cord-290297-efo9f7c5 51 14 in in IN cord-290297-efo9f7c5 51 15 influenza influenza NN cord-290297-efo9f7c5 51 16 : : : cord-290297-efo9f7c5 52 1 a a DT cord-290297-efo9f7c5 52 2 grand grand JJ cord-290297-efo9f7c5 52 3 rounds round NNS cord-290297-efo9f7c5 52 4 review review NN cord-290297-efo9f7c5 53 1 The the DT cord-290297-efo9f7c5 53 2 frequency frequency NN cord-290297-efo9f7c5 53 3 of of IN cord-290297-efo9f7c5 53 4 influenza influenza NN cord-290297-efo9f7c5 53 5 and and CC cord-290297-efo9f7c5 53 6 bacterial bacterial JJ cord-290297-efo9f7c5 53 7 coinfection coinfection NN cord-290297-efo9f7c5 53 8 : : : cord-290297-efo9f7c5 53 9 a a DT cord-290297-efo9f7c5 53 10 systematic systematic JJ cord-290297-efo9f7c5 53 11 review review NN cord-290297-efo9f7c5 53 12 and and CC cord-290297-efo9f7c5 53 13 meta meta JJ cord-290297-efo9f7c5 53 14 ᎑ ᎑ CD cord-290297-efo9f7c5 53 15 analysis analysis NN cord-290297-efo9f7c5 53 16 Influenza Influenza NNP cord-290297-efo9f7c5 53 17 - - HYPH cord-290297-efo9f7c5 53 18 associated associate VBN cord-290297-efo9f7c5 53 19 pediatric pediatric JJ cord-290297-efo9f7c5 53 20 mortality mortality NN cord-290297-efo9f7c5 53 21 in in IN cord-290297-efo9f7c5 53 22 the the DT cord-290297-efo9f7c5 53 23 United United NNP cord-290297-efo9f7c5 53 24 States States NNP cord-290297-efo9f7c5 53 25 : : : cord-290297-efo9f7c5 53 26 increase increase NN cord-290297-efo9f7c5 53 27 of of IN cord-290297-efo9f7c5 53 28 Staphylococcus Staphylococcus NNP cord-290297-efo9f7c5 53 29 aureus aureus NN cord-290297-efo9f7c5 53 30 coinfection coinfection NN cord-290297-efo9f7c5 53 31 Increase increase NN cord-290297-efo9f7c5 53 32 in in IN cord-290297-efo9f7c5 53 33 methicillin methicillin NN cord-290297-efo9f7c5 53 34 - - HYPH cord-290297-efo9f7c5 53 35 resistant resistant JJ cord-290297-efo9f7c5 53 36 Staphylococcus Staphylococcus NNP cord-290297-efo9f7c5 53 37 aureus aureus NN cord-290297-efo9f7c5 53 38 acquisition acquisition NN cord-290297-efo9f7c5 53 39 rate rate NN cord-290297-efo9f7c5 53 40 and and CC cord-290297-efo9f7c5 53 41 change change NN cord-290297-efo9f7c5 53 42 in in IN cord-290297-efo9f7c5 53 43 pathogen pathogen NN cord-290297-efo9f7c5 53 44 pattern pattern NN cord-290297-efo9f7c5 53 45 associated associate VBN cord-290297-efo9f7c5 53 46 with with IN cord-290297-efo9f7c5 53 47 an an DT cord-290297-efo9f7c5 53 48 outbreak outbreak NN cord-290297-efo9f7c5 53 49 of of IN cord-290297-efo9f7c5 53 50 severe severe JJ cord-290297-efo9f7c5 53 51 acute acute JJ cord-290297-efo9f7c5 53 52 respiratory respiratory JJ cord-290297-efo9f7c5 53 53 syndrome syndrome NN cord-290297-efo9f7c5 53 54 Streptococcus streptococcus NN cord-290297-efo9f7c5 53 55 pneumoniae pneumoniae NN cord-290297-efo9f7c5 53 56 coinfection coinfection NN cord-290297-efo9f7c5 53 57 is be VBZ cord-290297-efo9f7c5 53 58 correlated correlate VBN cord-290297-efo9f7c5 53 59 with with IN cord-290297-efo9f7c5 53 60 the the DT cord-290297-efo9f7c5 53 61 severity severity NN cord-290297-efo9f7c5 53 62 of of IN cord-290297-efo9f7c5 53 63 H1N1 H1N1 NNP cord-290297-efo9f7c5 53 64 pandemic pandemic NN cord-290297-efo9f7c5 53 65 influenza influenza NN cord-290297-efo9f7c5 53 66 Factors factor NNS cord-290297-efo9f7c5 53 67 associated associate VBN cord-290297-efo9f7c5 53 68 with with IN cord-290297-efo9f7c5 53 69 death death NN cord-290297-efo9f7c5 53 70 in in IN cord-290297-efo9f7c5 53 71 hospitalized hospitalize VBN cord-290297-efo9f7c5 53 72 pneumonia pneumonia NN cord-290297-efo9f7c5 53 73 patients patient NNS cord-290297-efo9f7c5 53 74 with with IN cord-290297-efo9f7c5 53 75 2009 2009 CD cord-290297-efo9f7c5 53 76 H1N1 H1N1 NNP cord-290297-efo9f7c5 53 77 influenza influenza NN cord-290297-efo9f7c5 53 78 in in IN cord-290297-efo9f7c5 53 79 Shenyang Shenyang NNP cord-290297-efo9f7c5 53 80 Pediatric Pediatric NNP cord-290297-efo9f7c5 53 81 Acute Acute NNP cord-290297-efo9f7c5 53 82 Lung Lung NNP cord-290297-efo9f7c5 53 83 Injury Injury NNP cord-290297-efo9f7c5 53 84 and and CC cord-290297-efo9f7c5 53 85 Sepsis Sepsis NNP cord-290297-efo9f7c5 53 86 Investigator Investigator NNP cord-290297-efo9f7c5 53 87 's 's POS cord-290297-efo9f7c5 53 88 Network Network NNP cord-290297-efo9f7c5 53 89 and and CC cord-290297-efo9f7c5 53 90 the the DT cord-290297-efo9f7c5 53 91 National National NNP cord-290297-efo9f7c5 53 92 Heart Heart NNP cord-290297-efo9f7c5 53 93 , , , cord-290297-efo9f7c5 53 94 Lung Lung NNP cord-290297-efo9f7c5 53 95 , , , cord-290297-efo9f7c5 53 96 and and CC cord-290297-efo9f7c5 53 97 Blood Blood NNP cord-290297-efo9f7c5 53 98 Institute Institute NNP cord-290297-efo9f7c5 53 99 ARDS ARDS NNP cord-290297-efo9f7c5 53 100 Clinical Clinical NNP cord-290297-efo9f7c5 53 101 Trials Trials NNPS cord-290297-efo9f7c5 53 102 Network Network NNP cord-290297-efo9f7c5 53 103 Lung Lung NNP cord-290297-efo9f7c5 53 104 pathology pathology NN cord-290297-efo9f7c5 53 105 of of IN cord-290297-efo9f7c5 53 106 severe severe JJ cord-290297-efo9f7c5 53 107 acute acute JJ cord-290297-efo9f7c5 53 108 respiratory respiratory JJ cord-290297-efo9f7c5 53 109 syndrome syndrome NN cord-290297-efo9f7c5 53 110 ( ( -LRB- cord-290297-efo9f7c5 53 111 SARS SARS NNP cord-290297-efo9f7c5 53 112 ) ) -RRB- cord-290297-efo9f7c5 53 113 : : : cord-290297-efo9f7c5 53 114 a a DT cord-290297-efo9f7c5 53 115 study study NN cord-290297-efo9f7c5 53 116 of of IN cord-290297-efo9f7c5 53 117 8 8 CD cord-290297-efo9f7c5 53 118 autopsy autopsy JJ cord-290297-efo9f7c5 53 119 cases case NNS cord-290297-efo9f7c5 53 120 from from IN cord-290297-efo9f7c5 53 121 Singapore Singapore NNP cord-290297-efo9f7c5 53 122 Pulmonary Pulmonary NNP cord-290297-efo9f7c5 53 123 pathological pathological JJ cord-290297-efo9f7c5 53 124 features feature NNS cord-290297-efo9f7c5 53 125 in in IN cord-290297-efo9f7c5 53 126 coronavirus coronavirus NN cord-290297-efo9f7c5 53 127 associated associate VBN cord-290297-efo9f7c5 53 128 severe severe JJ cord-290297-efo9f7c5 53 129 acute acute JJ cord-290297-efo9f7c5 53 130 respiratory respiratory JJ cord-290297-efo9f7c5 53 131 syndrome syndrome NN cord-290297-efo9f7c5 53 132 ( ( -LRB- cord-290297-efo9f7c5 53 133 SARS SARS NNP cord-290297-efo9f7c5 53 134 ) ) -RRB- cord-290297-efo9f7c5 53 135 Correlation correlation NN cord-290297-efo9f7c5 53 136 between between IN cord-290297-efo9f7c5 53 137 antimicrobial antimicrobial JJ cord-290297-efo9f7c5 53 138 consumption consumption NN cord-290297-efo9f7c5 53 139 and and CC cord-290297-efo9f7c5 53 140 incidence incidence NN cord-290297-efo9f7c5 53 141 of of IN cord-290297-efo9f7c5 53 142 health health NN cord-290297-efo9f7c5 53 143 - - HYPH cord-290297-efo9f7c5 53 144 careassociated careassociate VBN cord-290297-efo9f7c5 53 145 infections infection NNS cord-290297-efo9f7c5 53 146 due due JJ cord-290297-efo9f7c5 53 147 to to IN cord-290297-efo9f7c5 53 148 methicillin methicillin NN cord-290297-efo9f7c5 53 149 - - HYPH cord-290297-efo9f7c5 53 150 resistant resistant JJ cord-290297-efo9f7c5 53 151 Staphylococcus Staphylococcus NNP cord-290297-efo9f7c5 53 152 aureus aureus NN cord-290297-efo9f7c5 53 153 and and CC cord-290297-efo9f7c5 53 154 vancomycin vancomycin NN cord-290297-efo9f7c5 53 155 - - HYPH cord-290297-efo9f7c5 53 156 resistant resistant JJ cord-290297-efo9f7c5 53 157 enterococci enterococci NNS cord-290297-efo9f7c5 53 158 at at IN cord-290297-efo9f7c5 53 159 a a DT cord-290297-efo9f7c5 53 160 university university NN cord-290297-efo9f7c5 53 161 hospital hospital NN cord-290297-efo9f7c5 53 162 in in IN cord-290297-efo9f7c5 53 163 Taiwan Taiwan NNP cord-290297-efo9f7c5 53 164 from from IN cord-290297-efo9f7c5 53 165 2000 2000 CD cord-290297-efo9f7c5 53 166 to to IN cord-290297-efo9f7c5 53 167 2010 2010 CD cord-290297-efo9f7c5 53 168 Our -PRON- PRP$ cord-290297-efo9f7c5 53 169 contributions contribution NNS cord-290297-efo9f7c5 53 170 were be VBD cord-290297-efo9f7c5 53 171 as as IN cord-290297-efo9f7c5 53 172 follows follow VBZ cord-290297-efo9f7c5 53 173 : : : cord-290297-efo9f7c5 53 174 literature literature NN cord-290297-efo9f7c5 53 175 search search NN cord-290297-efo9f7c5 53 176 , , , cord-290297-efo9f7c5 53 177 M.V. M.V. NNP cord-290297-efo9f7c5 53 178 ; ; : cord-290297-efo9f7c5 53 179 writing writing NN cord-290297-efo9f7c5 53 180 , , , cord-290297-efo9f7c5 53 181 M.V. M.V. NNP cord-290297-efo9f7c5 53 182 and and CC cord-290297-efo9f7c5 53 183 P.J. P.J. NNP cord-290297-efo9f7c5 54 1 We -PRON- PRP cord-290297-efo9f7c5 54 2 declare declare VBP cord-290297-efo9f7c5 54 3 no no DT cord-290297-efo9f7c5 54 4 competing compete VBG cord-290297-efo9f7c5 54 5 interests interest NNS cord-290297-efo9f7c5 54 6 . . . cord-290297-efo9f7c5 55 1 P.J. P.J. NNP cord-290297-efo9f7c5 55 2 was be VBD cord-290297-efo9f7c5 55 3 supported support VBN cord-290297-efo9f7c5 55 4 by by IN cord-290297-efo9f7c5 55 5 grants grant NNS cord-290297-efo9f7c5 55 6 from from IN cord-290297-efo9f7c5 55 7 the the DT cord-290297-efo9f7c5 55 8 NIH NIH NNP cord-290297-efo9f7c5 55 9 ( ( -LRB- cord-290297-efo9f7c5 55 10 K22AI127473 K22AI127473 NNP cord-290297-efo9f7c5 55 11 and and CC cord-290297-efo9f7c5 55 12 UL1TR001881 UL1TR001881 NNP cord-290297-efo9f7c5 55 13 ) ) -RRB- cord-290297-efo9f7c5 55 14 and and CC cord-290297-efo9f7c5 55 15 the the DT cord-290297-efo9f7c5 55 16 Cystic Cystic NNP cord-290297-efo9f7c5 55 17 Fibrosis Fibrosis NNP cord-290297-efo9f7c5 55 18 Foundation Foundation NNP cord-290297-efo9f7c5 55 19 ( ( -LRB- cord-290297-efo9f7c5 55 20 JORTH17F5 JORTH17F5 NNP cord-290297-efo9f7c5 55 21 , , , cord-290297-efo9f7c5 55 22 PROMISE PROMISE NNP cord-290297-efo9f7c5 55 23 , , , cord-290297-efo9f7c5 55 24 JORTH19I0 JORTH19I0 NNP cord-290297-efo9f7c5 55 25 , , , cord-290297-efo9f7c5 55 26 JORTH19P0 JORTH19P0 NNP cord-290297-efo9f7c5 55 27 ) ) -RRB- cord-290297-efo9f7c5 55 28 . . .