id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-284990-klsl1nzn	Zhang, Dapeng	A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems	2011-02-08		.txt	text/plain	13700	564	41	By analyzing the toxin proteins encoded in the neighborhood of the SUKH superfamily we predict that they possess domains belonging to diverse nuclease and nucleic acid deaminase families. Our above observations indicate that outside of CDI systems, the SUKH superfamily genes are linked to genes encoding the HNH and NucA nucleases; hence, it is likely that even these nucleases function as distinct but analogous toxins that cleave nucleic acids in target cells. Together, the above observations raised the possibility that the SUKH superfamily protein might serve as immunity proteins, not just in certain proteobacterial CDI systems, but also more generally function, across all major bacterial lineages, to protect against linked genes, which are predicted to act as toxins. In bacteria the SUKH superfamily domains are one of the most widespread immunity proteins that appear to function in conjunction with a repertoire of nuclease toxins that are extremely diverse in sequence and structure (Figures 3 and 4) .	./cache/cord-284990-klsl1nzn.txt	./txt/cord-284990-klsl1nzn.txt