id author title date pages extension mime words sentences flesch summary cache txt cord-293311-dr2ysrwe Chew, Justin Nutrition Mediates the Relationship between Osteosarcopenia and Frailty: A Pathway Analysis 2020-09-27 .txt text/plain 3914 199 42 In this cross-sectional analysis of 230 independent, community-dwelling individuals (mean age 67.2 ± 7.4 years), we examined the associations between osteosarcopenia with nutritional status and frailty, and the mediating role of nutrition in the association between osteosarcopenia and frailty. Secondly, we investigated nutrition as a mediator of the relationship between osteosarcopenia and frailty, relative to osteoporosis and sarcopenia alone, in a cohort of independent community-dwelling older adults. A multicategorical mediation model examined the potential mediating role of nutrition, using total MNA score, in the relationship between osteoporosis, sarcopenia and osteosarcopenia with frailty. Our study demonstrated that in relatively healthy community-dwelling older adults, osteosarcopenia is present in 11.7% of individuals and is associated with markers of nutrition, including lower MNA scores, BMI, calf, mid-arm and waist circumference. The strengths of this study include the analysis of a reasonably-sized cohort of independent community-dwelling older adults, the use of contemporary consensus definitions for sarcopenia in an Asian population, and comprehensive evaluation of nutritional status. ./cache/cord-293311-dr2ysrwe.txt ./txt/cord-293311-dr2ysrwe.txt