id author title date pages extension mime words sentences flesch summary cache txt cord-298931-n1se3ajb Stańdo, Mirella Omega-3 Polyunsaturated Fatty Acids EPA and DHA as an Adjunct to Non-Surgical Treatment of Periodontitis: A Randomized Clinical Trial 2020-08-27 .txt text/plain 5763 294 47 demonstrating that dietary supplementation of omega-3 PUFA with non-surgical periodontal treatment had significant effect on clinical parameters such as gingival index (GI), BOP, PD and CAL, but no effect on serum C-reactive protein (CRP) level [12] . Similar to the results of our study, the decrease of BOP was demonstrated in the patients that received omega-3 PUFA in addition to the scaling and oral hygiene instructions versus control group, thus anti-inflammatory properties of EPA and DHA were also clinically detectable at the less advanced stages of periodontal inflammation [27, 28] . Another study demonstrated a significant reduction in PD and CAL in the group receiving omega-3 PUFA plus aspirin during non-surgical periodontal treatment compared to the control group, with significantly reduced levels of salivary RANKL and matrix metalloproteinase (MMP) 8 in the test group [29] . Dietary supplementation with low-dose omega-3 fatty acids reduces salivary tumor necrosis factor-α levels in patients with chronic periodontitis: A randomized controlled clinical study ./cache/cord-298931-n1se3ajb.txt ./txt/cord-298931-n1se3ajb.txt