id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327045-hn8pmcto	Li, Yao	Quercetin, Inflammation and Immunity	2016-03-15		.txt	text/plain	5360	292	40	In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. A study demonstrates that quercetin has a direct regulatory effect on basic functional properties of immune cells which may be mediated by the extracellular regulated kinase 2 (Erk2) mitogen-activated protein (MAP) kinase signal pathway in human mitogen-activated PBMC and purified T lymphocytes [54] . Quercetin most likely universally suppresses the accumulation and activation of immune cells, including anti-inflammatory cells, whereas it specifically increased gene expression associated with mitochondrial oxidative phosphorylation in Western diet-induced obese mice. showed that a supplement of 1000 mg of quercetin alone three weeks before, during and two weeks after a three-day period of 3 h of cycling in the winter resulted in a markedly lower incidence of URTI in well-trained subjects in the two weeks after the intensified training, but had no effect on exercise-induced immune dysfunction, inflammation and oxidative stress [76] .	./cache/cord-327045-hn8pmcto.txt	./txt/cord-327045-hn8pmcto.txt