id author title date pages extension mime words sentences flesch summary cache txt cord-333286-lr32e0w4 Lehtoranta, Liisa Role of Probiotics in Stimulating the Immune System in Viral Respiratory Tract Infections: A Narrative Review 2020-10-16 .txt text/plain 6768 338 35 We searched PubMed, Google Scholar, and Web of Knowledge for pre-clinical and clinical studies investigating the effect of probiotics on respiratory virus infections, immune response, and the course of upper and lower respiratory tract illness. Similar effects have been demonstrated in several mouse studies with the ability to reduce virus titers in lung tissues and modulation of antiviral and pro-inflammatory gene expression before and after viral infection. The upregulation of IFN response seems to prime cells for better resistance against virus infection as probiotics were shown effective in inhibiting the replication of various respiratory viruses, including influenza viruses and RSV. Similar effects have been demonstrated in mice with the ability of the probiotics to reduce virus titers in lung tissues and to modulate antiviral and pro-inflammatory gene expression before and after viral infection. Similar effects have been demonstrated in mice with the ability of the probiotics to reduce virus titers in lung tissues and to modulate antiviral and pro-inflammatory gene expression before and after viral infection. ./cache/cord-333286-lr32e0w4.txt ./txt/cord-333286-lr32e0w4.txt