id author title date pages extension mime words sentences flesch summary cache txt cord-336256-d5292aga Méplan, Catherine The Role of Selenium in Health and Disease: Emerging and Recurring Trends 2020-04-10 .txt text/plain 1773 68 30 In this Special Issue of Nutrients, "The Role of Selenium in Health and Disease" covers diverse diseases in the 8 original research articles and 2 reviews, such as cardiovascular disorders (CVD), metabolic syndrome, obesity, cancer, and viral infection, and highlights novel potential biomarkers of disease risk and prognosis [...]. The findings provide the most comprehensive evidence to date that individual genotypes relevant for selenoprotein expression, metabolism, and function and interaction with Se status may affect CRC risk in a population of marginally low Se status, such as in Europe. The review also summarises results from genetic association studies linking genotypes for SNPs in the SELENOF gene to risk for various cancers, Kashin-Beck disease, and AIDs progression, with a particular focus on two well-characterised functional SNPs (rs5845 and rs5859) affecting SELENOF protein expression. ./cache/cord-336256-d5292aga.txt ./txt/cord-336256-d5292aga.txt