id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-000680-vsgd9v1w	Lee, Linda K.	Clinical Relevance and Discriminatory Value of Elevated Liver Aminotransferase Levels for Dengue Severity	2012-06-05		.txt	text/plain	3553	197	57	We aimed to assess the clinical relevance and discriminatory value of AST or ALT for dengue hemorrhagic fever (DHF) and severe dengue. There was significant overlap in AST and ALT values among patients with dengue with or without warning signs and severe dengue, and between those with DF and DHF. In this study, we aimed to evaluate the clinical relevance of elevated AST and ALT levels and correlate liver aminotransferase levels with dengue severity according to WHO 1997 and 2009 classifications. We performed a subgroup analysis for median maximum AST and ALT values stratified by febrile (days 1-3 of illness), critical (days 4-6), and convalescent (days 7-10) phases as defined by WHO 2009 [1] and compared across dengue severity classification according to WHO 1997 [9] and 2009 [1] . In conclusion, elevated aminotransferase levels were associated with DHF/DSS and severe dengue in our cohort of adult patients with confirmed dengue.	./cache/cord-000680-vsgd9v1w.txt	./txt/cord-000680-vsgd9v1w.txt