id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290617-45be6gxe	Poulain, Florian	Footprint of the host restriction factors APOBEC3 on the genome of human viruses	2020-08-14		.txt	text/plain	10515	610	56	Certain viruses actively encode viral proteins antagonizing the APOBEC3s, others passively face the APOBEC3 selection pressure thanks to a depleted genome for APOBEC3-targeted motifs. By breaking down the human viruses into their respective Baltimore's group (S3 Fig), we observed that NTC depletion is not present in reverse transcribing nor in negative sense single strand RNA viruses. We also observed a mild general NCC depletion in single strand DNA and double strand RNA viruses, justifying further investigation for a possible A3G-induced footprint (S1 Fig). In order to identify A3-footprinted viruses, we detailed the NTC and NNGANN ratios for 870 human viral species (Fig 4A) . B. The observed/expected ratios of TC dinucleotide at various codon positions and on both strands (i.e. NNTCNN, TCN, NTC, GAN, NGA and NNGANN) were calculated for the putative A3-footprinted viral species and depicted by a heatmap.	./cache/cord-290617-45be6gxe.txt	./txt/cord-290617-45be6gxe.txt