id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312743-9e4yufo5	Breiman, Adrien	Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2	2020-05-21		.txt	text/plain	1388	66	45	These observations suggested that, when produced in cells that express the A or B blood group enzymes, infectious SARS virions are decorated by the corresponding glycan antigens and that the presence of anti-A and anti-B antibodies in blood group O individuals could prevent infection by blocking virus attachment and entry. We therefore hypothesize that as they are produced in cells coexpressing the ACE2 receptor and either the αGal, NeuGc, or A/B blood group antigens, both SARS-CoV and SARS-CoV2 harbor the corresponding glycan epitopes. Likewise, impairment of transmission by the anti-blood group antibodies may not work to its full potential because of their variable titers in the population and of the high affinity of the SARS-CoV2 for ACE2 [18] , rendering its neutralization more difficult.	./cache/cord-312743-9e4yufo5.txt	./txt/cord-312743-9e4yufo5.txt