id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334315-ymkrgj0h	Moon, Stephanie L.	Cytoplasmic Viruses: Rage against the (Cellular RNA Decay) Machine	2013-12-05		.txt	text/plain	1995	100	43	This review describes the myriad ways that viruses deal with the general host RNA decay machinery that is active in the cell immediately upon viral infection-turning what, at first, appears to be very hostile territory for a foreign transcript into a sort of ''promised land'' for viral gene expression. Disparate RNA viruses have, therefore, evolved unique mechanisms by which they disarm host RNA decay pathways by inactivating or proteolytically degrading important nucleases to promote productive viral infections. In addition, to make a cell more amenable to virus production, these virally encoded nucleases may also create a new ''sandbox'' in the cytoplasm for viral RNAs by initiating the large-scale decay of cellular mRNAs and dramatically altering the landscape of host gene expression. Considering the importance of RNA stability in regulating transcript abundance, the inactivation or commandeering of cellular RNA decay factors by viruses is likely to significantly alter host gene expression.	./cache/cord-334315-ymkrgj0h.txt	./txt/cord-334315-ymkrgj0h.txt