id	sid	tid	token	lemma	pos
cord-342419-liaihahj	1	1	key	key	JJ
cord-342419-liaihahj	2	1	:	:	:
cord-342419-liaihahj	2	2	cord-342419-liaihahj	cord-342419-liaihahj	CD
cord-342419-liaihahj	2	3	authors	author	NNS
cord-342419-liaihahj	2	4	:	:	:
cord-342419-liaihahj	2	5	Huang	Huang	NNP
cord-342419-liaihahj	2	6	,	,	,
cord-342419-liaihahj	2	7	Jiachen	Jiachen	NNP
cord-342419-liaihahj	2	8	;	;	:
cord-342419-liaihahj	2	9	Diaz	Diaz	NNP
cord-342419-liaihahj	2	10	,	,	,
cord-342419-liaihahj	2	11	Darren	Darren	NNP
cord-342419-liaihahj	2	12	;	;	:
cord-342419-liaihahj	2	13	Mousa	Mousa	NNP
cord-342419-liaihahj	2	14	,	,	,
cord-342419-liaihahj	2	15	Jarrod	Jarrod	NNP
cord-342419-liaihahj	2	16	J.	J.	NNP
cord-342419-liaihahj	2	17	title	title	NN
cord-342419-liaihahj	2	18	:	:	:
cord-342419-liaihahj	2	19	Antibody	antibody	NN
cord-342419-liaihahj	2	20	recognition	recognition	NN
cord-342419-liaihahj	2	21	of	of	IN
cord-342419-liaihahj	2	22	the	the	DT
cord-342419-liaihahj	2	23	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	2	24	fusion	fusion	NN
cord-342419-liaihahj	2	25	protein	protein	NN
cord-342419-liaihahj	2	26	trimer	trimer	NN
cord-342419-liaihahj	2	27	interface	interface	NN
cord-342419-liaihahj	2	28	date	date	NN
cord-342419-liaihahj	2	29	:	:	:
cord-342419-liaihahj	2	30	2020	2020	CD
cord-342419-liaihahj	2	31	-	-	SYM
cord-342419-liaihahj	2	32	10	10	CD
cord-342419-liaihahj	2	33	-	-	HYPH
cord-342419-liaihahj	2	34	09	09	CD
cord-342419-liaihahj	2	35	journal	journal	NN
cord-342419-liaihahj	2	36	:	:	:
cord-342419-liaihahj	3	1	PLoS	PLoS	NNP
cord-342419-liaihahj	3	2	Pathog	Pathog	NNP
cord-342419-liaihahj	3	3	DOI	DOI	NNP
cord-342419-liaihahj	3	4	:	:	:
cord-342419-liaihahj	3	5	10.1371/	10.1371/	CD
cord-342419-liaihahj	4	1	journal.ppat.1008942	journal.ppat.1008942	IN
cord-342419-liaihahj	4	2	sha	sha	NNP
cord-342419-liaihahj	4	3	:	:	:
cord-342419-liaihahj	4	4	f456b5e11ad70c3cf65c56824013550bcb6e3bfe	f456b5e11ad70c3cf65c56824013550bcb6e3bfe	VB
cord-342419-liaihahj	4	5	doc_id	doc_id	CD
cord-342419-liaihahj	4	6	:	:	:
cord-342419-liaihahj	4	7	342419	342419	CD
cord-342419-liaihahj	4	8	cord_uid	cord_uid	NNS
cord-342419-liaihahj	4	9	:	:	:
cord-342419-liaihahj	5	1	liaihahj	liaihahj	NNP
cord-342419-liaihahj	5	2	Human	Human	NNP
cord-342419-liaihahj	5	3	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	5	4	(	(	-LRB-
cord-342419-liaihahj	5	5	hMPV	hMPV	NNP
cord-342419-liaihahj	5	6	)	)	-RRB-
cord-342419-liaihahj	5	7	is	be	VBZ
cord-342419-liaihahj	5	8	a	a	DT
cord-342419-liaihahj	5	9	leading	leading	JJ
cord-342419-liaihahj	5	10	cause	cause	NN
cord-342419-liaihahj	5	11	of	of	IN
cord-342419-liaihahj	5	12	viral	viral	JJ
cord-342419-liaihahj	5	13	respiratory	respiratory	JJ
cord-342419-liaihahj	5	14	infection	infection	NN
cord-342419-liaihahj	5	15	in	in	IN
cord-342419-liaihahj	5	16	children	child	NNS
cord-342419-liaihahj	5	17	,	,	,
cord-342419-liaihahj	5	18	and	and	CC
cord-342419-liaihahj	5	19	can	can	MD
cord-342419-liaihahj	5	20	cause	cause	VB
cord-342419-liaihahj	5	21	severe	severe	JJ
cord-342419-liaihahj	5	22	lower	low	JJR
cord-342419-liaihahj	5	23	respiratory	respiratory	JJ
cord-342419-liaihahj	5	24	tract	tract	NN
cord-342419-liaihahj	5	25	infection	infection	NN
cord-342419-liaihahj	5	26	in	in	IN
cord-342419-liaihahj	5	27	infants	infant	NNS
cord-342419-liaihahj	5	28	,	,	,
cord-342419-liaihahj	5	29	the	the	DT
cord-342419-liaihahj	5	30	elderly	elderly	JJ
cord-342419-liaihahj	5	31	,	,	,
cord-342419-liaihahj	5	32	and	and	CC
cord-342419-liaihahj	5	33	immunocompromised	immunocompromised	JJ
cord-342419-liaihahj	5	34	patients	patient	NNS
cord-342419-liaihahj	5	35	.	.	.
cord-342419-liaihahj	6	1	However	however	RB
cord-342419-liaihahj	6	2	,	,	,
cord-342419-liaihahj	6	3	there	there	EX
cord-342419-liaihahj	6	4	remain	remain	VBP
cord-342419-liaihahj	6	5	no	no	DT
cord-342419-liaihahj	6	6	licensed	licensed	JJ
cord-342419-liaihahj	6	7	vaccines	vaccine	NNS
cord-342419-liaihahj	6	8	or	or	CC
cord-342419-liaihahj	6	9	specific	specific	JJ
cord-342419-liaihahj	6	10	treatments	treatment	NNS
cord-342419-liaihahj	6	11	for	for	IN
cord-342419-liaihahj	6	12	hMPV	hmpv	NN
cord-342419-liaihahj	6	13	infection	infection	NN
cord-342419-liaihahj	6	14	.	.	.
cord-342419-liaihahj	7	1	Although	although	IN
cord-342419-liaihahj	7	2	the	the	DT
cord-342419-liaihahj	7	3	hMPV	hmpv	NN
cord-342419-liaihahj	7	4	fusion	fusion	NN
cord-342419-liaihahj	7	5	(	(	-LRB-
cord-342419-liaihahj	7	6	F	F	NNP
cord-342419-liaihahj	7	7	)	)	-RRB-
cord-342419-liaihahj	7	8	protein	protein	NN
cord-342419-liaihahj	7	9	is	be	VBZ
cord-342419-liaihahj	7	10	the	the	DT
cord-342419-liaihahj	7	11	sole	sole	JJ
cord-342419-liaihahj	7	12	target	target	NN
cord-342419-liaihahj	7	13	of	of	IN
cord-342419-liaihahj	7	14	neutralizing	neutralize	VBG
cord-342419-liaihahj	7	15	antibodies	antibody	NNS
cord-342419-liaihahj	7	16	,	,	,
cord-342419-liaihahj	7	17	the	the	DT
cord-342419-liaihahj	7	18	immunological	immunological	JJ
cord-342419-liaihahj	7	19	properties	property	NNS
cord-342419-liaihahj	7	20	of	of	IN
cord-342419-liaihahj	7	21	hMPV	hmpv	NN
cord-342419-liaihahj	7	22	F	F	NNP
cord-342419-liaihahj	7	23	remain	remain	VBP
cord-342419-liaihahj	7	24	poorly	poorly	RB
cord-342419-liaihahj	7	25	understood	understand	VBN
cord-342419-liaihahj	7	26	.	.	.
cord-342419-liaihahj	8	1	To	to	TO
cord-342419-liaihahj	8	2	further	further	RB
cord-342419-liaihahj	8	3	define	define	VB
cord-342419-liaihahj	8	4	the	the	DT
cord-342419-liaihahj	8	5	humoral	humoral	JJ
cord-342419-liaihahj	8	6	immune	immune	JJ
cord-342419-liaihahj	8	7	response	response	NN
cord-342419-liaihahj	8	8	to	to	IN
cord-342419-liaihahj	8	9	the	the	DT
cord-342419-liaihahj	8	10	hMPV	hmpv	NN
cord-342419-liaihahj	8	11	F	F	NNP
cord-342419-liaihahj	8	12	protein	protein	NN
cord-342419-liaihahj	8	13	,	,	,
cord-342419-liaihahj	8	14	we	-PRON-	PRP
cord-342419-liaihahj	8	15	isolated	isolate	VBD
cord-342419-liaihahj	8	16	two	two	CD
cord-342419-liaihahj	8	17	new	new	JJ
cord-342419-liaihahj	8	18	human	human	JJ
cord-342419-liaihahj	8	19	monoclonal	monoclonal	JJ
cord-342419-liaihahj	8	20	antibodies	antibody	NNS
cord-342419-liaihahj	8	21	(	(	-LRB-
cord-342419-liaihahj	8	22	mAbs	mAbs	NNP
cord-342419-liaihahj	8	23	)	)	-RRB-
cord-342419-liaihahj	8	24	,	,	,
cord-342419-liaihahj	8	25	MPV458	MPV458	NNP
cord-342419-liaihahj	8	26	and	and	CC
cord-342419-liaihahj	8	27	MPV465	MPV465	NNP
cord-342419-liaihahj	8	28	.	.	.
cord-342419-liaihahj	9	1	Both	both	DT
cord-342419-liaihahj	9	2	mAbs	mAbs	NNP
cord-342419-liaihahj	9	3	are	be	VBP
cord-342419-liaihahj	9	4	neutralizing	neutralize	VBG
cord-342419-liaihahj	9	5	in	in	IN
cord-342419-liaihahj	9	6	vitro	vitro	FW
cord-342419-liaihahj	9	7	and	and	CC
cord-342419-liaihahj	9	8	were	be	VBD
cord-342419-liaihahj	9	9	determined	determine	VBN
cord-342419-liaihahj	9	10	to	to	TO
cord-342419-liaihahj	9	11	target	target	VB
cord-342419-liaihahj	9	12	a	a	DT
cord-342419-liaihahj	9	13	unique	unique	JJ
cord-342419-liaihahj	9	14	antigenic	antigenic	JJ
cord-342419-liaihahj	9	15	site	site	NN
cord-342419-liaihahj	9	16	using	use	VBG
cord-342419-liaihahj	9	17	competitive	competitive	JJ
cord-342419-liaihahj	9	18	biolayer	biolayer	NN
cord-342419-liaihahj	9	19	interferometry	interferometry	NN
cord-342419-liaihahj	9	20	.	.	.
cord-342419-liaihahj	10	1	We	-PRON-	PRP
cord-342419-liaihahj	10	2	determined	determine	VBD
cord-342419-liaihahj	10	3	both	both	CC
cord-342419-liaihahj	10	4	MPV458	MPV458	NNP
cord-342419-liaihahj	10	5	and	and	CC
cord-342419-liaihahj	10	6	MPV465	MPV465	NNP
cord-342419-liaihahj	10	7	have	have	VB
cord-342419-liaihahj	10	8	higher	high	JJR
cord-342419-liaihahj	10	9	affinity	affinity	NN
cord-342419-liaihahj	10	10	for	for	IN
cord-342419-liaihahj	10	11	monomeric	monomeric	JJ
cord-342419-liaihahj	10	12	hMPV	hmpv	NN
cord-342419-liaihahj	10	13	F	f	NN
cord-342419-liaihahj	11	1	than	than	IN
cord-342419-liaihahj	11	2	trimeric	trimeric	NNP
cord-342419-liaihahj	11	3	hMPV	hmpv	NN
cord-342419-liaihahj	11	4	F.	F.	NNP
cord-342419-liaihahj	11	5	MPV458	MPV458	NNP
cord-342419-liaihahj	11	6	was	be	VBD
cord-342419-liaihahj	11	7	co	co	JJ
cord-342419-liaihahj	11	8	-	-	JJ
cord-342419-liaihahj	11	9	crystallized	crystallize	VBN
cord-342419-liaihahj	12	1	with	with	IN
cord-342419-liaihahj	12	2	hMPV	hMPV	NNP
cord-342419-liaihahj	12	3	F	F	NNP
cord-342419-liaihahj	12	4	,	,	,
cord-342419-liaihahj	13	1	and	and	CC
cord-342419-liaihahj	13	2	the	the	DT
cord-342419-liaihahj	13	3	mAb	mAb	NNS
cord-342419-liaihahj	13	4	primarily	primarily	RB
cord-342419-liaihahj	13	5	interacts	interact	VBZ
cord-342419-liaihahj	13	6	with	with	IN
cord-342419-liaihahj	13	7	an	an	DT
cord-342419-liaihahj	13	8	alpha	alpha	NN
cord-342419-liaihahj	13	9	helix	helix	NN
cord-342419-liaihahj	13	10	on	on	IN
cord-342419-liaihahj	13	11	the	the	DT
cord-342419-liaihahj	13	12	F2	F2	NNP
cord-342419-liaihahj	13	13	region	region	NN
cord-342419-liaihahj	13	14	of	of	IN
cord-342419-liaihahj	13	15	the	the	DT
cord-342419-liaihahj	13	16	hMPV	hmpv	NN
cord-342419-liaihahj	13	17	F	F	NNP
cord-342419-liaihahj	13	18	protein	protein	NN
cord-342419-liaihahj	13	19	.	.	.
cord-342419-liaihahj	14	1	Surprisingly	surprisingly	RB
cord-342419-liaihahj	14	2	,	,	,
cord-342419-liaihahj	14	3	the	the	DT
cord-342419-liaihahj	14	4	major	major	JJ
cord-342419-liaihahj	14	5	epitope	epitope	NN
cord-342419-liaihahj	14	6	for	for	IN
cord-342419-liaihahj	14	7	MPV458	MPV458	NNP
cord-342419-liaihahj	14	8	lies	lie	VBZ
cord-342419-liaihahj	14	9	within	within	IN
cord-342419-liaihahj	14	10	the	the	DT
cord-342419-liaihahj	14	11	trimeric	trimeric	JJ
cord-342419-liaihahj	14	12	interface	interface	NN
cord-342419-liaihahj	14	13	of	of	IN
cord-342419-liaihahj	14	14	the	the	DT
cord-342419-liaihahj	14	15	hMPV	hmpv	NN
cord-342419-liaihahj	14	16	F	F	NNP
cord-342419-liaihahj	14	17	protein	protein	NN
cord-342419-liaihahj	14	18	,	,	,
cord-342419-liaihahj	14	19	suggesting	suggest	VBG
cord-342419-liaihahj	14	20	significant	significant	JJ
cord-342419-liaihahj	14	21	breathing	breathing	NN
cord-342419-liaihahj	14	22	of	of	IN
cord-342419-liaihahj	14	23	the	the	DT
cord-342419-liaihahj	14	24	hMPV	hmpv	NN
cord-342419-liaihahj	14	25	F	F	NNP
cord-342419-liaihahj	14	26	protein	protein	NN
cord-342419-liaihahj	14	27	must	must	MD
cord-342419-liaihahj	14	28	occur	occur	VB
cord-342419-liaihahj	14	29	for	for	IN
cord-342419-liaihahj	14	30	host	host	NN
cord-342419-liaihahj	14	31	immune	immune	JJ
cord-342419-liaihahj	14	32	recognition	recognition	NN
cord-342419-liaihahj	14	33	of	of	IN
cord-342419-liaihahj	14	34	the	the	DT
cord-342419-liaihahj	14	35	novel	novel	JJ
cord-342419-liaihahj	14	36	epitope	epitope	NN
cord-342419-liaihahj	14	37	.	.	.
cord-342419-liaihahj	15	1	In	in	IN
cord-342419-liaihahj	15	2	addition	addition	NN
cord-342419-liaihahj	15	3	,	,	,
cord-342419-liaihahj	15	4	significant	significant	JJ
cord-342419-liaihahj	15	5	glycan	glycan	NN
cord-342419-liaihahj	15	6	interactions	interaction	NNS
cord-342419-liaihahj	15	7	were	be	VBD
cord-342419-liaihahj	15	8	observed	observe	VBN
cord-342419-liaihahj	15	9	with	with	IN
cord-342419-liaihahj	15	10	a	a	DT
cord-342419-liaihahj	15	11	somatically	somatically	RB
cord-342419-liaihahj	15	12	mutated	mutate	VBN
cord-342419-liaihahj	15	13	light	light	JJ
cord-342419-liaihahj	15	14	chain	chain	NN
cord-342419-liaihahj	15	15	framework	framework	NN
cord-342419-liaihahj	15	16	residue	residue	NN
cord-342419-liaihahj	15	17	.	.	.
cord-342419-liaihahj	16	1	The	the	DT
cord-342419-liaihahj	16	2	data	datum	NNS
cord-342419-liaihahj	16	3	presented	present	VBD
cord-342419-liaihahj	16	4	identifies	identify	VBZ
cord-342419-liaihahj	16	5	a	a	DT
cord-342419-liaihahj	16	6	novel	novel	JJ
cord-342419-liaihahj	16	7	epitope	epitope	NN
cord-342419-liaihahj	16	8	on	on	IN
cord-342419-liaihahj	16	9	the	the	DT
cord-342419-liaihahj	16	10	hMPV	hmpv	NN
cord-342419-liaihahj	16	11	F	F	NNP
cord-342419-liaihahj	16	12	protein	protein	NN
cord-342419-liaihahj	16	13	for	for	IN
cord-342419-liaihahj	16	14	epitope	epitope	NN
cord-342419-liaihahj	16	15	-	-	HYPH
cord-342419-liaihahj	16	16	based	base	VBN
cord-342419-liaihahj	16	17	vaccine	vaccine	NN
cord-342419-liaihahj	16	18	design	design	NN
cord-342419-liaihahj	16	19	,	,	,
cord-342419-liaihahj	16	20	and	and	CC
cord-342419-liaihahj	16	21	illustrates	illustrate	VBZ
cord-342419-liaihahj	16	22	a	a	DT
cord-342419-liaihahj	16	23	new	new	JJ
cord-342419-liaihahj	16	24	mechanism	mechanism	NN
cord-342419-liaihahj	16	25	for	for	IN
cord-342419-liaihahj	16	26	human	human	JJ
cord-342419-liaihahj	16	27	antibody	antibody	NN
cord-342419-liaihahj	16	28	neutralization	neutralization	NN
cord-342419-liaihahj	16	29	of	of	IN
cord-342419-liaihahj	16	30	viral	viral	JJ
cord-342419-liaihahj	16	31	glycoproteins	glycoprotein	NNS
cord-342419-liaihahj	16	32	.	.	.
cord-342419-liaihahj	17	1	Human	Human	NNP
cord-342419-liaihahj	17	2	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	17	3	(	(	-LRB-
cord-342419-liaihahj	17	4	hMPV	hMPV	NNP
cord-342419-liaihahj	17	5	)	)	-RRB-
cord-342419-liaihahj	17	6	is	be	VBZ
cord-342419-liaihahj	17	7	a	a	DT
cord-342419-liaihahj	17	8	common	common	JJ
cord-342419-liaihahj	17	9	cause	cause	NN
cord-342419-liaihahj	17	10	of	of	IN
cord-342419-liaihahj	17	11	lower	low	JJR
cord-342419-liaihahj	17	12	respiratory	respiratory	JJ
cord-342419-liaihahj	17	13	tract	tract	NN
cord-342419-liaihahj	17	14	infection	infection	NN
cord-342419-liaihahj	17	15	in	in	IN
cord-342419-liaihahj	17	16	children	child	NNS
cord-342419-liaihahj	17	17	,	,	,
cord-342419-liaihahj	17	18	the	the	DT
cord-342419-liaihahj	17	19	elderly	elderly	JJ
cord-342419-liaihahj	17	20	,	,	,
cord-342419-liaihahj	17	21	and	and	CC
cord-342419-liaihahj	17	22	the	the	DT
cord-342419-liaihahj	17	23	immunocompromised	immunocompromised	JJ
cord-342419-liaihahj	17	24	.	.	.
cord-342419-liaihahj	18	1	There	there	EX
cord-342419-liaihahj	18	2	is	be	VBZ
cord-342419-liaihahj	18	3	currently	currently	RB
cord-342419-liaihahj	18	4	no	no	DT
cord-342419-liaihahj	18	5	approved	approve	VBN
cord-342419-liaihahj	18	6	vaccine	vaccine	NN
cord-342419-liaihahj	18	7	or	or	CC
cord-342419-liaihahj	18	8	therapeutic	therapeutic	JJ
cord-342419-liaihahj	18	9	to	to	TO
cord-342419-liaihahj	18	10	prevent	prevent	VB
cord-342419-liaihahj	18	11	or	or	CC
cord-342419-liaihahj	18	12	treat	treat	VB
cord-342419-liaihahj	18	13	hMPV	hmpv	NN
cord-342419-liaihahj	18	14	infection	infection	NN
cord-342419-liaihahj	18	15	.	.	.
cord-342419-liaihahj	19	1	The	the	DT
cord-342419-liaihahj	19	2	hMPV	hmpv	NN
cord-342419-liaihahj	19	3	fusion	fusion	NN
cord-342419-liaihahj	19	4	(	(	-LRB-
cord-342419-liaihahj	19	5	F	F	NNP
cord-342419-liaihahj	19	6	)	)	-RRB-
cord-342419-liaihahj	19	7	protein	protein	NN
cord-342419-liaihahj	19	8	is	be	VBZ
cord-342419-liaihahj	19	9	the	the	DT
cord-342419-liaihahj	19	10	sole	sole	JJ
cord-342419-liaihahj	19	11	target	target	NN
cord-342419-liaihahj	19	12	of	of	IN
cord-342419-liaihahj	19	13	antibodies	antibody	NNS
cord-342419-liaihahj	19	14	that	that	WDT
cord-342419-liaihahj	19	15	neutralize	neutralize	VBP
cord-342419-liaihahj	19	16	hMPV	hmpv	NN
cord-342419-liaihahj	19	17	.	.	.
cord-342419-liaihahj	20	1	Here	here	RB
cord-342419-liaihahj	20	2	we	-PRON-	PRP
cord-342419-liaihahj	20	3	describe	describe	VBP
cord-342419-liaihahj	20	4	new	new	JJ
cord-342419-liaihahj	20	5	human	human	JJ
cord-342419-liaihahj	20	6	mAbs	mAbs	NNP
cord-342419-liaihahj	20	7	that	that	WDT
cord-342419-liaihahj	20	8	bind	bind	VBP
cord-342419-liaihahj	20	9	a	a	DT
cord-342419-liaihahj	20	10	unique	unique	JJ
cord-342419-liaihahj	20	11	epitope	epitope	NN
cord-342419-liaihahj	20	12	on	on	IN
cord-342419-liaihahj	20	13	the	the	DT
cord-342419-liaihahj	20	14	hMPV	hmpv	NN
cord-342419-liaihahj	20	15	F	F	NNP
cord-342419-liaihahj	20	16	protein	protein	NN
cord-342419-liaihahj	20	17	.	.	.
cord-342419-liaihahj	21	1	The	the	DT
cord-342419-liaihahj	21	2	mAbs	mabs	NN
cord-342419-liaihahj	21	3	were	be	VBD
cord-342419-liaihahj	21	4	mapped	map	VBN
cord-342419-liaihahj	21	5	to	to	IN
cord-342419-liaihahj	21	6	a	a	DT
cord-342419-liaihahj	21	7	new	new	JJ
cord-342419-liaihahj	21	8	antigenic	antigenic	JJ
cord-342419-liaihahj	21	9	site	site	NN
cord-342419-liaihahj	21	10	on	on	IN
cord-342419-liaihahj	21	11	the	the	DT
cord-342419-liaihahj	21	12	hMPV	hmpv	NN
cord-342419-liaihahj	21	13	F	F	NNP
cord-342419-liaihahj	21	14	protein	protein	NN
cord-342419-liaihahj	21	15	located	locate	VBN
cord-342419-liaihahj	21	16	within	within	IN
cord-342419-liaihahj	21	17	the	the	DT
cord-342419-liaihahj	21	18	trimeric	trimeric	JJ
cord-342419-liaihahj	21	19	interface	interface	NN
cord-342419-liaihahj	21	20	of	of	IN
cord-342419-liaihahj	21	21	the	the	DT
cord-342419-liaihahj	21	22	hMPV	hmpv	NN
cord-342419-liaihahj	21	23	F	F	NNP
cord-342419-liaihahj	21	24	protein	protein	NN
cord-342419-liaihahj	21	25	based	base	VBN
cord-342419-liaihahj	21	26	on	on	IN
cord-342419-liaihahj	21	27	competitive	competitive	JJ
cord-342419-liaihahj	21	28	biolayer	biolayer	NN
cord-342419-liaihahj	21	29	interferometry	interferometry	NN
cord-342419-liaihahj	21	30	and	and	CC
cord-342419-liaihahj	21	31	X	x	NN
cord-342419-liaihahj	21	32	-	-	NN
cord-342419-liaihahj	21	33	ray	ray	JJ
cord-342419-liaihahj	21	34	crystallographic	crystallographic	JJ
cord-342419-liaihahj	21	35	experiments	experiment	NNS
cord-342419-liaihahj	21	36	.	.	.
cord-342419-liaihahj	22	1	This	this	DT
cord-342419-liaihahj	22	2	is	be	VBZ
cord-342419-liaihahj	22	3	the	the	DT
cord-342419-liaihahj	22	4	first	first	JJ
cord-342419-liaihahj	22	5	example	example	NN
cord-342419-liaihahj	22	6	of	of	IN
cord-342419-liaihahj	22	7	a	a	DT
cord-342419-liaihahj	22	8	human	human	JJ
cord-342419-liaihahj	22	9	mAb	mAb	NNS
cord-342419-liaihahj	22	10	that	that	WDT
cord-342419-liaihahj	22	11	binds	bind	VBZ
cord-342419-liaihahj	22	12	inside	inside	IN
cord-342419-liaihahj	22	13	the	the	DT
cord-342419-liaihahj	22	14	trimeric	trimeric	JJ
cord-342419-liaihahj	22	15	interface	interface	NN
cord-342419-liaihahj	22	16	of	of	IN
cord-342419-liaihahj	22	17	a	a	DT
cord-342419-liaihahj	22	18	viral	viral	JJ
cord-342419-liaihahj	22	19	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	22	20	and	and	CC
cord-342419-liaihahj	22	21	neutralizes	neutralize	VBZ
cord-342419-liaihahj	22	22	the	the	DT
cord-342419-liaihahj	22	23	virus	virus	NN
cord-342419-liaihahj	22	24	.	.	.
cord-342419-liaihahj	23	1	The	the	DT
cord-342419-liaihahj	23	2	results	result	NNS
cord-342419-liaihahj	23	3	suggest	suggest	VBP
cord-342419-liaihahj	23	4	such	such	JJ
cord-342419-liaihahj	23	5	antibodies	antibody	NNS
cord-342419-liaihahj	23	6	may	may	MD
cord-342419-liaihahj	23	7	 	 	_SP
cord-342419-liaihahj	23	8	Human	Human	NNP
cord-342419-liaihahj	23	9	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	23	10	(	(	-LRB-
cord-342419-liaihahj	23	11	hMPV	hMPV	NNP
cord-342419-liaihahj	23	12	)	)	-RRB-
cord-342419-liaihahj	23	13	is	be	VBZ
cord-342419-liaihahj	23	14	a	a	DT
cord-342419-liaihahj	23	15	leading	leading	JJ
cord-342419-liaihahj	23	16	cause	cause	NN
cord-342419-liaihahj	23	17	of	of	IN
cord-342419-liaihahj	23	18	viral	viral	JJ
cord-342419-liaihahj	23	19	respiratory	respiratory	JJ
cord-342419-liaihahj	23	20	infections	infection	NNS
cord-342419-liaihahj	23	21	in	in	IN
cord-342419-liaihahj	23	22	children	child	NNS
cord-342419-liaihahj	23	23	,	,	,
cord-342419-liaihahj	23	24	the	the	DT
cord-342419-liaihahj	23	25	majority	majority	NN
cord-342419-liaihahj	23	26	of	of	IN
cord-342419-liaihahj	23	27	whom	whom	WP
cord-342419-liaihahj	23	28	are	be	VBP
cord-342419-liaihahj	23	29	seropositive	seropositive	JJ
cord-342419-liaihahj	23	30	for	for	IN
cord-342419-liaihahj	23	31	hMPV	hmpv	NN
cord-342419-liaihahj	23	32	by	by	IN
cord-342419-liaihahj	23	33	five	five	CD
cord-342419-liaihahj	23	34	years	year	NNS
cord-342419-liaihahj	23	35	of	of	IN
cord-342419-liaihahj	23	36	age	age	NN
cord-342419-liaihahj	23	37	[	[	-LRB-
cord-342419-liaihahj	23	38	1	1	CD
cord-342419-liaihahj	23	39	]	]	-RRB-
cord-342419-liaihahj	23	40	.	.	.
cord-342419-liaihahj	24	1	Although	although	IN
cord-342419-liaihahj	24	2	hMPV	hmpv	NN
cord-342419-liaihahj	24	3	was	be	VBD
cord-342419-liaihahj	24	4	discovered	discover	VBN
cord-342419-liaihahj	24	5	in	in	IN
cord-342419-liaihahj	24	6	2001	2001	CD
cord-342419-liaihahj	24	7	[	[	-LRB-
cord-342419-liaihahj	24	8	2	2	CD
cord-342419-liaihahj	24	9	]	]	-RRB-
cord-342419-liaihahj	24	10	,	,	,
cord-342419-liaihahj	24	11	there	there	EX
cord-342419-liaihahj	24	12	are	be	VBP
cord-342419-liaihahj	24	13	no	no	DT
cord-342419-liaihahj	24	14	vaccines	vaccine	NNS
cord-342419-liaihahj	24	15	or	or	CC
cord-342419-liaihahj	24	16	therapeutics	therapeutic	NNS
cord-342419-liaihahj	24	17	approved	approve	VBN
cord-342419-liaihahj	24	18	to	to	TO
cord-342419-liaihahj	24	19	prevent	prevent	VB
cord-342419-liaihahj	24	20	or	or	CC
cord-342419-liaihahj	24	21	treat	treat	VB
cord-342419-liaihahj	24	22	viral	viral	JJ
cord-342419-liaihahj	24	23	infection	infection	NN
cord-342419-liaihahj	24	24	.	.	.
cord-342419-liaihahj	25	1	Similar	similar	JJ
cord-342419-liaihahj	25	2	to	to	IN
cord-342419-liaihahj	25	3	other	other	JJ
cord-342419-liaihahj	25	4	respiratory	respiratory	JJ
cord-342419-liaihahj	25	5	pathogens	pathogen	NNS
cord-342419-liaihahj	25	6	,	,	,
cord-342419-liaihahj	25	7	children	child	NNS
cord-342419-liaihahj	25	8	,	,	,
cord-342419-liaihahj	25	9	the	the	DT
cord-342419-liaihahj	25	10	elderly	elderly	JJ
cord-342419-liaihahj	25	11	,	,	,
cord-342419-liaihahj	25	12	and	and	CC
cord-342419-liaihahj	25	13	the	the	DT
cord-342419-liaihahj	25	14	immunocompromised	immunocompromised	NNS
cord-342419-liaihahj	25	15	are	be	VBP
cord-342419-liaihahj	25	16	the	the	DT
cord-342419-liaihahj	25	17	major	major	JJ
cord-342419-liaihahj	25	18	groups	group	NNS
cord-342419-liaihahj	25	19	for	for	IN
cord-342419-liaihahj	25	20	which	which	WDT
cord-342419-liaihahj	25	21	hMPV	hmpv	NN
cord-342419-liaihahj	25	22	infection	infection	NN
cord-342419-liaihahj	25	23	may	may	MD
cord-342419-liaihahj	25	24	require	require	VB
cord-342419-liaihahj	25	25	hospitalization	hospitalization	NN
cord-342419-liaihahj	25	26	[	[	-LRB-
cord-342419-liaihahj	25	27	3	3	CD
cord-342419-liaihahj	25	28	]	]	-RRB-
cord-342419-liaihahj	25	29	[	[	-LRB-
cord-342419-liaihahj	25	30	4	4	CD
cord-342419-liaihahj	25	31	]	]	-RRB-
cord-342419-liaihahj	25	32	[	[	-LRB-
cord-342419-liaihahj	25	33	5	5	CD
cord-342419-liaihahj	25	34	]	]	-RRB-
cord-342419-liaihahj	25	35	[	[	-LRB-
cord-342419-liaihahj	25	36	6	6	CD
cord-342419-liaihahj	25	37	]	]	-RRB-
cord-342419-liaihahj	25	38	[	[	-LRB-
cord-342419-liaihahj	25	39	7	7	CD
cord-342419-liaihahj	25	40	]	]	-RRB-
cord-342419-liaihahj	25	41	[	[	-LRB-
cord-342419-liaihahj	25	42	8	8	CD
cord-342419-liaihahj	25	43	]	]	-RRB-
cord-342419-liaihahj	25	44	[	[	-LRB-
cord-342419-liaihahj	25	45	9	9	CD
cord-342419-liaihahj	25	46	]	]	-RRB-
cord-342419-liaihahj	25	47	[	[	-LRB-
cord-342419-liaihahj	25	48	10	10	CD
cord-342419-liaihahj	25	49	]	]	-RRB-
cord-342419-liaihahj	25	50	[	[	-LRB-
cord-342419-liaihahj	25	51	11	11	CD
cord-342419-liaihahj	25	52	]	]	-RRB-
cord-342419-liaihahj	25	53	.	.	.
cord-342419-liaihahj	26	1	Several	several	JJ
cord-342419-liaihahj	26	2	reports	report	NNS
cord-342419-liaihahj	26	3	have	have	VBP
cord-342419-liaihahj	26	4	demonstrated	demonstrate	VBN
cord-342419-liaihahj	26	5	hMPV	hmpv	NN
cord-342419-liaihahj	26	6	infection	infection	NN
cord-342419-liaihahj	26	7	can	can	MD
cord-342419-liaihahj	26	8	be	be	VB
cord-342419-liaihahj	26	9	lethal	lethal	JJ
cord-342419-liaihahj	26	10	in	in	IN
cord-342419-liaihahj	26	11	both	both	DT
cord-342419-liaihahj	26	12	adults	adult	NNS
cord-342419-liaihahj	26	13	and	and	CC
cord-342419-liaihahj	26	14	children	child	NNS
cord-342419-liaihahj	26	15	.	.	.
cord-342419-liaihahj	27	1	In	in	IN
cord-342419-liaihahj	27	2	particular	particular	JJ
cord-342419-liaihahj	27	3	,	,	,
cord-342419-liaihahj	27	4	haemopoietic	haemopoietic	JJ
cord-342419-liaihahj	27	5	stem	stem	NN
cord-342419-liaihahj	27	6	cell	cell	NN
cord-342419-liaihahj	27	7	transplant	transplant	NN
cord-342419-liaihahj	27	8	patients	patient	NNS
cord-342419-liaihahj	27	9	are	be	VBP
cord-342419-liaihahj	27	10	at	at	IN
cord-342419-liaihahj	27	11	high	high	JJ
cord-342419-liaihahj	27	12	risk	risk	NN
cord-342419-liaihahj	27	13	of	of	IN
cord-342419-liaihahj	27	14	severe	severe	JJ
cord-342419-liaihahj	27	15	hMPV	hmpv	NN
cord-342419-liaihahj	27	16	infection	infection	NN
cord-342419-liaihahj	27	17	[	[	-LRB-
cord-342419-liaihahj	27	18	10	10	CD
cord-342419-liaihahj	27	19	]	]	-RRB-
cord-342419-liaihahj	27	20	[	[	-LRB-
cord-342419-liaihahj	27	21	11	11	CD
cord-342419-liaihahj	27	22	]	]	-RRB-
cord-342419-liaihahj	27	23	[	[	-LRB-
cord-342419-liaihahj	27	24	12	12	CD
cord-342419-liaihahj	27	25	]	]	-RRB-
cord-342419-liaihahj	27	26	[	[	-LRB-
cord-342419-liaihahj	27	27	13	13	CD
cord-342419-liaihahj	27	28	]	]	-RRB-
cord-342419-liaihahj	27	29	,	,	,
cord-342419-liaihahj	27	30	and	and	CC
cord-342419-liaihahj	27	31	several	several	JJ
cord-342419-liaihahj	27	32	outbreaks	outbreak	NNS
cord-342419-liaihahj	27	33	of	of	IN
cord-342419-liaihahj	27	34	hMPV	hmpv	NN
cord-342419-liaihahj	27	35	in	in	IN
cord-342419-liaihahj	27	36	nursing	nursing	NN
cord-342419-liaihahj	27	37	homes	home	NNS
cord-342419-liaihahj	27	38	have	have	VBP
cord-342419-liaihahj	27	39	been	be	VBN
cord-342419-liaihahj	27	40	reported	report	VBN
cord-342419-liaihahj	27	41	[	[	-LRB-
cord-342419-liaihahj	27	42	14	14	CD
cord-342419-liaihahj	27	43	]	]	-RRB-
cord-342419-liaihahj	27	44	[	[	-LRB-
cord-342419-liaihahj	27	45	15	15	CD
cord-342419-liaihahj	27	46	]	]	-RRB-
cord-342419-liaihahj	27	47	[	[	-LRB-
cord-342419-liaihahj	27	48	16	16	CD
cord-342419-liaihahj	27	49	]	]	-RRB-
cord-342419-liaihahj	27	50	.	.	.
cord-342419-liaihahj	28	1	In	in	IN
cord-342419-liaihahj	28	2	addition	addition	NN
cord-342419-liaihahj	28	3	,	,	,
cord-342419-liaihahj	28	4	fatal	fatal	JJ
cord-342419-liaihahj	28	5	hMPV	hmpv	NN
cord-342419-liaihahj	28	6	has	have	VBZ
cord-342419-liaihahj	28	7	been	be	VBN
cord-342419-liaihahj	28	8	observed	observe	VBN
cord-342419-liaihahj	28	9	in	in	IN
cord-342419-liaihahj	28	10	one	one	CD
cord-342419-liaihahj	28	11	child	child	NN
cord-342419-liaihahj	28	12	during	during	IN
cord-342419-liaihahj	28	13	an	an	DT
cord-342419-liaihahj	28	14	outbreak	outbreak	NN
cord-342419-liaihahj	28	15	of	of	IN
cord-342419-liaihahj	28	16	hMPV	hmpv	NN
cord-342419-liaihahj	28	17	in	in	IN
cord-342419-liaihahj	28	18	a	a	DT
cord-342419-liaihahj	28	19	daycare	daycare	NN
cord-342419-liaihahj	28	20	center	center	NN
cord-342419-liaihahj	28	21	[	[	-LRB-
cord-342419-liaihahj	28	22	17	17	CD
cord-342419-liaihahj	28	23	]	]	-RRB-
cord-342419-liaihahj	28	24	.	.	.
cord-342419-liaihahj	29	1	hMPV	hMPV	NNP
cord-342419-liaihahj	29	2	is	be	VBZ
cord-342419-liaihahj	29	3	also	also	RB
cord-342419-liaihahj	29	4	a	a	DT
cord-342419-liaihahj	29	5	significant	significant	JJ
cord-342419-liaihahj	29	6	cause	cause	NN
cord-342419-liaihahj	29	7	of	of	IN
cord-342419-liaihahj	29	8	febrile	febrile	JJ
cord-342419-liaihahj	29	9	respiratory	respiratory	JJ
cord-342419-liaihahj	29	10	illness	illness	NN
cord-342419-liaihahj	29	11	in	in	IN
cord-342419-liaihahj	29	12	HIV	HIV	NNP
cord-342419-liaihahj	29	13	-	-	HYPH
cord-342419-liaihahj	29	14	infected	infect	VBN
cord-342419-liaihahj	29	15	patients	patient	NNS
cord-342419-liaihahj	29	16	[	[	-LRB-
cord-342419-liaihahj	29	17	18	18	CD
cord-342419-liaihahj	29	18	]	]	-RRB-
cord-342419-liaihahj	29	19	,	,	,
cord-342419-liaihahj	29	20	and	and	CC
cord-342419-liaihahj	29	21	has	have	VBZ
cord-342419-liaihahj	29	22	been	be	VBN
cord-342419-liaihahj	29	23	linked	link	VBN
cord-342419-liaihahj	29	24	to	to	IN
cord-342419-liaihahj	29	25	exacerbations	exacerbation	NNS
cord-342419-liaihahj	29	26	of	of	IN
cord-342419-liaihahj	29	27	chronic	chronic	JJ
cord-342419-liaihahj	29	28	obstructive	obstructive	JJ
cord-342419-liaihahj	29	29	pulmonary	pulmonary	JJ
cord-342419-liaihahj	29	30	disease	disease	NN
cord-342419-liaihahj	29	31	[	[	-LRB-
cord-342419-liaihahj	29	32	19	19	CD
cord-342419-liaihahj	29	33	]	]	-RRB-
cord-342419-liaihahj	29	34	.	.	.
cord-342419-liaihahj	30	1	Co	co	NN
cord-342419-liaihahj	30	2	-	-	NN
cord-342419-liaihahj	30	3	circulation	circulation	NN
cord-342419-liaihahj	30	4	of	of	IN
cord-342419-liaihahj	30	5	hMPV	hmpv	NN
cord-342419-liaihahj	30	6	was	be	VBD
cord-342419-liaihahj	30	7	observed	observe	VBN
cord-342419-liaihahj	30	8	during	during	IN
cord-342419-liaihahj	30	9	the	the	DT
cord-342419-liaihahj	30	10	SARS	SARS	NNP
cord-342419-liaihahj	30	11	outbreak	outbreak	NN
cord-342419-liaihahj	30	12	of	of	IN
cord-342419-liaihahj	30	13	2003	2003	CD
cord-342419-liaihahj	30	14	[	[	-LRB-
cord-342419-liaihahj	30	15	20	20	CD
cord-342419-liaihahj	30	16	]	]	-RRB-
cord-342419-liaihahj	30	17	[	[	-LRB-
cord-342419-liaihahj	30	18	21	21	CD
cord-342419-liaihahj	30	19	]	]	-RRB-
cord-342419-liaihahj	30	20	[	[	-LRB-
cord-342419-liaihahj	30	21	22	22	CD
cord-342419-liaihahj	30	22	]	]	-RRB-
cord-342419-liaihahj	30	23	,	,	,
cord-342419-liaihahj	30	24	and	and	CC
cord-342419-liaihahj	30	25	similar	similar	JJ
cord-342419-liaihahj	30	26	observations	observation	NNS
cord-342419-liaihahj	30	27	have	have	VBP
cord-342419-liaihahj	30	28	been	be	VBN
cord-342419-liaihahj	30	29	made	make	VBN
cord-342419-liaihahj	30	30	during	during	IN
cord-342419-liaihahj	30	31	the	the	DT
cord-342419-liaihahj	30	32	current	current	JJ
cord-342419-liaihahj	30	33	SARS	SARS	NNP
cord-342419-liaihahj	30	34	-	-	HYPH
cord-342419-liaihahj	30	35	CoV-2	CoV-2	NNP
cord-342419-liaihahj	30	36	pandemic	pandemic	NN
cord-342419-liaihahj	30	37	[	[	-LRB-
cord-342419-liaihahj	30	38	23	23	CD
cord-342419-liaihahj	30	39	,	,	,
cord-342419-liaihahj	30	40	24	24	CD
cord-342419-liaihahj	30	41	]	]	-RRB-
cord-342419-liaihahj	30	42	,	,	,
cord-342419-liaihahj	30	43	suggesting	suggest	VBG
cord-342419-liaihahj	30	44	hMPV	hmpv	NN
cord-342419-liaihahj	30	45	interacts	interact	VBZ
cord-342419-liaihahj	30	46	with	with	IN
cord-342419-liaihahj	30	47	other	other	JJ
cord-342419-liaihahj	30	48	circulating	circulate	VBG
cord-342419-liaihahj	30	49	respiratory	respiratory	JJ
cord-342419-liaihahj	30	50	viruses	virus	NNS
cord-342419-liaihahj	30	51	.	.	.
cord-342419-liaihahj	31	1	hMPV	hMPV	NNP
cord-342419-liaihahj	31	2	circulates	circulate	VBZ
cord-342419-liaihahj	31	3	as	as	IN
cord-342419-liaihahj	31	4	two	two	CD
cord-342419-liaihahj	31	5	genotypes	genotype	NNS
cord-342419-liaihahj	31	6	,	,	,
cord-342419-liaihahj	31	7	A	a	NN
cord-342419-liaihahj	31	8	and	and	CC
cord-342419-liaihahj	31	9	B	b	NN
cord-342419-liaihahj	31	10	,	,	,
cord-342419-liaihahj	31	11	and	and	CC
cord-342419-liaihahj	31	12	based	base	VBN
cord-342419-liaihahj	31	13	on	on	IN
cord-342419-liaihahj	31	14	the	the	DT
cord-342419-liaihahj	31	15	sequence	sequence	NN
cord-342419-liaihahj	31	16	variability	variability	NN
cord-342419-liaihahj	31	17	of	of	IN
cord-342419-liaihahj	31	18	the	the	DT
cord-342419-liaihahj	31	19	surface	surface	NN
cord-342419-liaihahj	31	20	proteins	protein	NNS
cord-342419-liaihahj	31	21	,	,	,
cord-342419-liaihahj	31	22	hMPV	hmpv	NN
cord-342419-liaihahj	31	23	is	be	VBZ
cord-342419-liaihahj	31	24	further	further	RB
cord-342419-liaihahj	31	25	grouped	group	VBN
cord-342419-liaihahj	31	26	into	into	IN
cord-342419-liaihahj	31	27	four	four	CD
cord-342419-liaihahj	31	28	subgroups	subgroup	NNS
cord-342419-liaihahj	31	29	,	,	,
cord-342419-liaihahj	31	30	A1	A1	NNP
cord-342419-liaihahj	31	31	,	,	,
cord-342419-liaihahj	31	32	A2	A2	NNP
cord-342419-liaihahj	31	33	,	,	,
cord-342419-liaihahj	31	34	B1	b1	NN
cord-342419-liaihahj	31	35	,	,	,
cord-342419-liaihahj	31	36	and	and	CC
cord-342419-liaihahj	31	37	B2	b2	NN
cord-342419-liaihahj	31	38	[	[	-LRB-
cord-342419-liaihahj	31	39	25	25	CD
cord-342419-liaihahj	31	40	,	,	,
cord-342419-liaihahj	31	41	26	26	CD
cord-342419-liaihahj	31	42	]	]	-RRB-
cord-342419-liaihahj	31	43	,	,	,
cord-342419-liaihahj	31	44	and	and	CC
cord-342419-liaihahj	31	45	two	two	CD
cord-342419-liaihahj	31	46	additional	additional	JJ
cord-342419-liaihahj	31	47	subgroups	subgroup	NNS
cord-342419-liaihahj	31	48	,	,	,
cord-342419-liaihahj	31	49	A2a	a2a	NN
cord-342419-liaihahj	31	50	and	and	CC
cord-342419-liaihahj	31	51	A2b	A2b	NNP
cord-342419-liaihahj	31	52	,	,	,
cord-342419-liaihahj	31	53	have	have	VBP
cord-342419-liaihahj	31	54	been	be	VBN
cord-342419-liaihahj	31	55	proposed	propose	VBN
cord-342419-liaihahj	31	56	[	[	-LRB-
cord-342419-liaihahj	31	57	12	12	CD
cord-342419-liaihahj	31	58	]	]	-RRB-
cord-342419-liaihahj	31	59	.	.	.
cord-342419-liaihahj	32	1	hMPV	hMPV	NNP
cord-342419-liaihahj	32	2	has	have	VBZ
cord-342419-liaihahj	32	3	three	three	CD
cord-342419-liaihahj	32	4	surface	surface	NN
cord-342419-liaihahj	32	5	glycoproteins	glycoprotein	NNS
cord-342419-liaihahj	32	6	,	,	,
cord-342419-liaihahj	32	7	the	the	DT
cord-342419-liaihahj	32	8	small	small	JJ
cord-342419-liaihahj	32	9	hydrophobic	hydrophobic	JJ
cord-342419-liaihahj	32	10	(	(	-LRB-
cord-342419-liaihahj	32	11	SH	SH	NNP
cord-342419-liaihahj	32	12	)	)	-RRB-
cord-342419-liaihahj	32	13	,	,	,
cord-342419-liaihahj	32	14	the	the	DT
cord-342419-liaihahj	32	15	attachment	attachment	NN
cord-342419-liaihahj	32	16	(	(	-LRB-
cord-342419-liaihahj	32	17	G	G	NNP
cord-342419-liaihahj	32	18	)	)	-RRB-
cord-342419-liaihahj	32	19	,	,	,
cord-342419-liaihahj	32	20	and	and	CC
cord-342419-liaihahj	32	21	the	the	DT
cord-342419-liaihahj	32	22	fusion	fusion	NN
cord-342419-liaihahj	32	23	(	(	-LRB-
cord-342419-liaihahj	32	24	F	F	NNP
cord-342419-liaihahj	32	25	)	)	-RRB-
cord-342419-liaihahj	32	26	proteins	protein	NNS
cord-342419-liaihahj	32	27	.	.	.
cord-342419-liaihahj	33	1	The	the	DT
cord-342419-liaihahj	33	2	hMPV	hmpv	NN
cord-342419-liaihahj	33	3	SH	sh	NN
cord-342419-liaihahj	33	4	protein	protein	NN
cord-342419-liaihahj	33	5	has	have	VBZ
cord-342419-liaihahj	33	6	been	be	VBN
cord-342419-liaihahj	33	7	demonstrated	demonstrate	VBN
cord-342419-liaihahj	33	8	to	to	TO
cord-342419-liaihahj	33	9	have	have	VB
cord-342419-liaihahj	33	10	viroporin	viroporin	NN
cord-342419-liaihahj	33	11	activity	activity	NN
cord-342419-liaihahj	33	12	[	[	-LRB-
cord-342419-liaihahj	33	13	27	27	CD
cord-342419-liaihahj	33	14	]	]	-RRB-
cord-342419-liaihahj	33	15	,	,	,
cord-342419-liaihahj	33	16	while	while	IN
cord-342419-liaihahj	33	17	the	the	DT
cord-342419-liaihahj	33	18	hMPV	hmpv	NN
cord-342419-liaihahj	33	19	G	g	NN
cord-342419-liaihahj	33	20	protein	protein	NN
cord-342419-liaihahj	33	21	has	have	VBZ
cord-342419-liaihahj	33	22	been	be	VBN
cord-342419-liaihahj	33	23	hypothesized	hypothesize	VBN
cord-342419-liaihahj	33	24	to	to	TO
cord-342419-liaihahj	33	25	be	be	VB
cord-342419-liaihahj	33	26	involved	involve	VBN
cord-342419-liaihahj	33	27	in	in	IN
cord-342419-liaihahj	33	28	cellular	cellular	JJ
cord-342419-liaihahj	33	29	attachment	attachment	NN
cord-342419-liaihahj	33	30	[	[	-LRB-
cord-342419-liaihahj	33	31	28	28	CD
cord-342419-liaihahj	33	32	]	]	-RRB-
cord-342419-liaihahj	33	33	.	.	.
cord-342419-liaihahj	34	1	The	the	DT
cord-342419-liaihahj	34	2	hMPV	hmpv	NN
cord-342419-liaihahj	34	3	F	F	NNP
cord-342419-liaihahj	34	4	protein	protein	NN
cord-342419-liaihahj	34	5	is	be	VBZ
cord-342419-liaihahj	34	6	indispensable	indispensable	JJ
cord-342419-liaihahj	34	7	for	for	IN
cord-342419-liaihahj	34	8	hMPV	hmpv	NN
cord-342419-liaihahj	34	9	infection	infection	NN
cord-342419-liaihahj	34	10	,	,	,
cord-342419-liaihahj	34	11	and	and	CC
cord-342419-liaihahj	34	12	is	be	VBZ
cord-342419-liaihahj	34	13	highly	highly	RB
cord-342419-liaihahj	34	14	conserved	conserve	VBN
cord-342419-liaihahj	34	15	among	among	IN
cord-342419-liaihahj	34	16	hMPV	hmpv	NN
cord-342419-liaihahj	34	17	subgroups	subgroup	NNS
cord-342419-liaihahj	34	18	[	[	-LRB-
cord-342419-liaihahj	34	19	29	29	CD
cord-342419-liaihahj	34	20	]	]	-RRB-
cord-342419-liaihahj	34	21	.	.	.
cord-342419-liaihahj	35	1	Furthermore	furthermore	RB
cord-342419-liaihahj	35	2	,	,	,
cord-342419-liaihahj	35	3	the	the	DT
cord-342419-liaihahj	35	4	hMPV	hmpv	NN
cord-342419-liaihahj	35	5	F	F	NNP
cord-342419-liaihahj	35	6	protein	protein	NN
cord-342419-liaihahj	35	7	is	be	VBZ
cord-342419-liaihahj	35	8	the	the	DT
cord-342419-liaihahj	35	9	sole	sole	JJ
cord-342419-liaihahj	35	10	target	target	NN
cord-342419-liaihahj	35	11	of	of	IN
cord-342419-liaihahj	35	12	neutralizing	neutralize	VBG
cord-342419-liaihahj	35	13	antibodies	antibody	NNS
cord-342419-liaihahj	35	14	[	[	-LRB-
cord-342419-liaihahj	35	15	30	30	CD
cord-342419-liaihahj	35	16	]	]	-RRB-
cord-342419-liaihahj	35	17	.	.	.
cord-342419-liaihahj	36	1	Although	although	IN
cord-342419-liaihahj	36	2	the	the	DT
cord-342419-liaihahj	36	3	hMPV	hmpv	NN
cord-342419-liaihahj	36	4	G	g	NN
cord-342419-liaihahj	36	5	protein	protein	NN
cord-342419-liaihahj	36	6	is	be	VBZ
cord-342419-liaihahj	36	7	thought	think	VBN
cord-342419-liaihahj	36	8	to	to	TO
cord-342419-liaihahj	36	9	interact	interact	VB
cord-342419-liaihahj	36	10	with	with	IN
cord-342419-liaihahj	36	11	proteoglycans	proteoglycan	NNS
cord-342419-liaihahj	36	12	,	,	,
cord-342419-liaihahj	36	13	the	the	DT
cord-342419-liaihahj	36	14	hMPV	hmpv	NN
cord-342419-liaihahj	36	15	F	F	NNP
cord-342419-liaihahj	36	16	protein	protein	NN
cord-342419-liaihahj	36	17	can	can	MD
cord-342419-liaihahj	36	18	interact	interact	VB
cord-342419-liaihahj	36	19	with	with	IN
cord-342419-liaihahj	36	20	glycans	glycan	NNS
cord-342419-liaihahj	36	21	in	in	IN
cord-342419-liaihahj	36	22	the	the	DT
cord-342419-liaihahj	36	23	absence	absence	NN
cord-342419-liaihahj	36	24	of	of	IN
cord-342419-liaihahj	36	25	hMPV	hmpv	NN
cord-342419-liaihahj	36	26	G	G	NNP
cord-342419-liaihahj	36	27	[	[	-LRB-
cord-342419-liaihahj	36	28	31	31	CD
cord-342419-liaihahj	36	29	]	]	-RRB-
cord-342419-liaihahj	36	30	.	.	.
cord-342419-liaihahj	37	1	The	the	DT
cord-342419-liaihahj	37	2	hMPV	hmpv	NN
cord-342419-liaihahj	37	3	F	F	NNP
cord-342419-liaihahj	37	4	protein	protein	NN
cord-342419-liaihahj	37	5	contains	contain	VBZ
cord-342419-liaihahj	37	6	a	a	DT
cord-342419-liaihahj	37	7	highly	highly	RB
cord-342419-liaihahj	37	8	conserved	conserve	VBN
cord-342419-liaihahj	37	9	RGD	RGD	NNP
cord-342419-liaihahj	37	10	motif	motif	NN
cord-342419-liaihahj	37	11	that	that	WDT
cord-342419-liaihahj	37	12	has	have	VBZ
cord-342419-liaihahj	37	13	been	be	VBN
cord-342419-liaihahj	37	14	proposed	propose	VBN
cord-342419-liaihahj	37	15	as	as	IN
cord-342419-liaihahj	37	16	a	a	DT
cord-342419-liaihahj	37	17	key	key	JJ
cord-342419-liaihahj	37	18	region	region	NN
cord-342419-liaihahj	37	19	in	in	IN
cord-342419-liaihahj	37	20	receptor	receptor	NN
cord-342419-liaihahj	37	21	binding	bind	VBG
cord-342419-liaihahj	37	22	to	to	IN
cord-342419-liaihahj	37	23	cellular	cellular	JJ
cord-342419-liaihahj	37	24	integrins	integrin	NNS
cord-342419-liaihahj	37	25	[	[	-LRB-
cord-342419-liaihahj	37	26	32	32	CD
cord-342419-liaihahj	37	27	,	,	,
cord-342419-liaihahj	37	28	33	33	CD
cord-342419-liaihahj	37	29	]	]	-RRB-
cord-342419-liaihahj	37	30	.	.	.
cord-342419-liaihahj	38	1	The	the	DT
cord-342419-liaihahj	38	2	entry	entry	NN
cord-342419-liaihahj	38	3	of	of	IN
cord-342419-liaihahj	38	4	hMPV	hmpv	NN
cord-342419-liaihahj	38	5	into	into	IN
cord-342419-liaihahj	38	6	the	the	DT
cord-342419-liaihahj	38	7	host	host	NN
cord-342419-liaihahj	38	8	cell	cell	NN
cord-342419-liaihahj	38	9	can	can	MD
cord-342419-liaihahj	38	10	occur	occur	VB
cord-342419-liaihahj	38	11	by	by	IN
cord-342419-liaihahj	38	12	cell	cell	NN
cord-342419-liaihahj	38	13	membrane	membrane	NN
cord-342419-liaihahj	38	14	or	or	CC
cord-342419-liaihahj	38	15	endosomal	endosomal	NNP
cord-342419-liaihahj	38	16	membrane	membrane	NN
cord-342419-liaihahj	38	17	fusion	fusion	NN
cord-342419-liaihahj	38	18	[	[	-LRB-
cord-342419-liaihahj	38	19	34	34	CD
cord-342419-liaihahj	38	20	]	]	-RRB-
cord-342419-liaihahj	38	21	.	.	.
cord-342419-liaihahj	39	1	Both	both	DT
cord-342419-liaihahj	39	2	hMPV	hmpv	NN
cord-342419-liaihahj	39	3	and	and	CC
cord-342419-liaihahj	39	4	the	the	DT
cord-342419-liaihahj	39	5	related	related	JJ
cord-342419-liaihahj	39	6	respiratory	respiratory	JJ
cord-342419-liaihahj	39	7	syncytial	syncytial	JJ
cord-342419-liaihahj	39	8	virus	virus	NN
cord-342419-liaihahj	39	9	(	(	-LRB-
cord-342419-liaihahj	39	10	RSV	RSV	NNP
cord-342419-liaihahj	39	11	)	)	-RRB-
cord-342419-liaihahj	39	12	are	be	VBP
cord-342419-liaihahj	39	13	members	member	NNS
cord-342419-liaihahj	39	14	of	of	IN
cord-342419-liaihahj	39	15	the	the	DT
cord-342419-liaihahj	39	16	Pneumoviridae	Pneumoviridae	NNP
cord-342419-liaihahj	39	17	family	family	NN
cord-342419-liaihahj	39	18	,	,	,
cord-342419-liaihahj	39	19	and	and	CC
cord-342419-liaihahj	39	20	share	share	VB
cord-342419-liaihahj	39	21	a	a	DT
cord-342419-liaihahj	39	22	structurally	structurally	RB
cord-342419-liaihahj	39	23	similar	similar	JJ
cord-342419-liaihahj	39	24	F	F	NNP
cord-342419-liaihahj	39	25	protein	protein	NN
cord-342419-liaihahj	39	26	that	that	WDT
cord-342419-liaihahj	39	27	has	have	VBZ
cord-342419-liaihahj	39	28	approximately	approximately	RB
cord-342419-liaihahj	39	29	30	30	CD
cord-342419-liaihahj	39	30	%	%	NN
cord-342419-liaihahj	39	31	homology	homology	NN
cord-342419-liaihahj	39	32	between	between	IN
cord-342419-liaihahj	39	33	the	the	DT
cord-342419-liaihahj	39	34	two	two	CD
cord-342419-liaihahj	39	35	viruses	virus	NNS
cord-342419-liaihahj	39	36	.	.	.
cord-342419-liaihahj	40	1	For	for	IN
cord-342419-liaihahj	40	2	both	both	DT
cord-342419-liaihahj	40	3	viruses	virus	NNS
cord-342419-liaihahj	40	4	,	,	,
cord-342419-liaihahj	40	5	the	the	DT
cord-342419-liaihahj	40	6	F	F	NNP
cord-342419-liaihahj	40	7	protein	protein	NN
cord-342419-liaihahj	40	8	has	have	VBZ
cord-342419-liaihahj	40	9	two	two	CD
cord-342419-liaihahj	40	10	long	long	RB
cord-342419-liaihahj	40	11	-	-	HYPH
cord-342419-liaihahj	40	12	lived	live	VBN
cord-342419-liaihahj	40	13	conformations	conformation	NNS
cord-342419-liaihahj	40	14	,	,	,
cord-342419-liaihahj	40	15	the	the	DT
cord-342419-liaihahj	40	16	pre	pre	JJ
cord-342419-liaihahj	40	17	-	-	JJ
cord-342419-liaihahj	40	18	fusion	fusion	JJ
cord-342419-liaihahj	40	19	and	and	CC
cord-342419-liaihahj	40	20	post	post	JJ
cord-342419-liaihahj	40	21	-	-	JJ
cord-342419-liaihahj	40	22	fusion	fusion	JJ
cord-342419-liaihahj	40	23	states	state	NNS
cord-342419-liaihahj	40	24	[	[	-LRB-
cord-342419-liaihahj	40	25	35	35	CD
cord-342419-liaihahj	40	26	]	]	-RRB-
cord-342419-liaihahj	40	27	.	.	.
cord-342419-liaihahj	41	1	Both	both	DT
cord-342419-liaihahj	41	2	RSV	RSV	NNP
cord-342419-liaihahj	41	3	and	and	CC
cord-342419-liaihahj	41	4	hMPV	hmpv	NN
cord-342419-liaihahj	41	5	lacking	lack	VBG
cord-342419-liaihahj	41	6	the	the	DT
cord-342419-liaihahj	41	7	G	g	NN
cord-342419-liaihahj	41	8	protein	protein	NN
cord-342419-liaihahj	41	9	can	can	MD
cord-342419-liaihahj	41	10	infect	infect	VB
cord-342419-liaihahj	41	11	cells	cell	NNS
cord-342419-liaihahj	41	12	in	in	IN
cord-342419-liaihahj	41	13	vitro	vitro	FW
cord-342419-liaihahj	41	14	,	,	,
cord-342419-liaihahj	41	15	although	although	IN
cord-342419-liaihahj	41	16	these	these	DT
cord-342419-liaihahj	41	17	viruses	virus	NNS
cord-342419-liaihahj	41	18	are	be	VBP
cord-342419-liaihahj	41	19	attenuated	attenuate	VBN
cord-342419-liaihahj	41	20	in	in	IN
cord-342419-liaihahj	41	21	vivo	vivo	NNP
cord-342419-liaihahj	41	22	[	[	-LRB-
cord-342419-liaihahj	41	23	36	36	CD
cord-342419-liaihahj	41	24	]	]	-RRB-
cord-342419-liaihahj	41	25	.	.	.
cord-342419-liaihahj	42	1	Both	both	DT
cord-342419-liaihahj	42	2	RSV	RSV	NNP
cord-342419-liaihahj	42	3	G	G	NNP
cord-342419-liaihahj	42	4	and	and	CC
cord-342419-liaihahj	42	5	hMPV	hmpv	NN
cord-342419-liaihahj	42	6	G	g	NN
cord-342419-liaihahj	42	7	proteins	protein	NNS
cord-342419-liaihahj	42	8	are	be	VBP
cord-342419-liaihahj	42	9	immunogenic	immunogenic	JJ
cord-342419-liaihahj	42	10	,	,	,
cord-342419-liaihahj	42	11	yet	yet	CC
cord-342419-liaihahj	42	12	only	only	RB
cord-342419-liaihahj	42	13	antibodies	antibody	NNS
cord-342419-liaihahj	42	14	to	to	IN
cord-342419-liaihahj	42	15	RSV	RSV	NNP
cord-342419-liaihahj	42	16	G	G	NNP
cord-342419-liaihahj	42	17	are	be	VBP
cord-342419-liaihahj	42	18	neutralizing	neutralize	VBG
cord-342419-liaihahj	42	19	[	[	-LRB-
cord-342419-liaihahj	42	20	30	30	CD
cord-342419-liaihahj	42	21	,	,	,
cord-342419-liaihahj	42	22	37	37	CD
cord-342419-liaihahj	42	23	]	]	-RRB-
cord-342419-liaihahj	42	24	.	.	.
cord-342419-liaihahj	43	1	The	the	DT
cord-342419-liaihahj	43	2	pre	pre	JJ
cord-342419-liaihahj	43	3	-	-	JJ
cord-342419-liaihahj	43	4	fusion	fusion	JJ
cord-342419-liaihahj	43	5	conformation	conformation	NN
cord-342419-liaihahj	43	6	of	of	IN
cord-342419-liaihahj	43	7	the	the	DT
cord-342419-liaihahj	43	8	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	43	9	F	F	NNP
cord-342419-liaihahj	43	10	protein	protein	NN
cord-342419-liaihahj	43	11	is	be	VBZ
cord-342419-liaihahj	43	12	meta	meta	JJ
cord-342419-liaihahj	43	13	-	-	HYPH
cord-342419-liaihahj	43	14	stable	stable	JJ
cord-342419-liaihahj	43	15	,	,	,
cord-342419-liaihahj	43	16	and	and	CC
cord-342419-liaihahj	43	17	stabilized	stabilize	VBD
cord-342419-liaihahj	43	18	versions	version	NNS
cord-342419-liaihahj	43	19	of	of	IN
cord-342419-liaihahj	43	20	both	both	DT
cord-342419-liaihahj	43	21	hMPV	hmpv	NN
cord-342419-liaihahj	43	22	F	F	NNP
cord-342419-liaihahj	43	23	[	[	-LRB-
cord-342419-liaihahj	43	24	38	38	CD
cord-342419-liaihahj	43	25	]	]	-RRB-
cord-342419-liaihahj	43	26	and	and	CC
cord-342419-liaihahj	43	27	RSV	RSV	NNP
cord-342419-liaihahj	43	28	F	F	NNP
cord-342419-liaihahj	43	29	[	[	-LRB-
cord-342419-liaihahj	43	30	39	39	CD
cord-342419-liaihahj	43	31	,	,	,
cord-342419-liaihahj	43	32	40	40	CD
cord-342419-liaihahj	43	33	]	]	-RRB-
cord-342419-liaihahj	43	34	have	have	VBP
cord-342419-liaihahj	43	35	been	be	VBN
cord-342419-liaihahj	43	36	generated	generate	VBN
cord-342419-liaihahj	43	37	.	.	.
cord-342419-liaihahj	44	1	The	the	DT
cord-342419-liaihahj	44	2	RSV	RSV	NNP
cord-342419-liaihahj	44	3	F	F	NNP
cord-342419-liaihahj	44	4	protein	protein	NN
cord-342419-liaihahj	44	5	was	be	VBD
cord-342419-liaihahj	44	6	initially	initially	RB
cord-342419-liaihahj	44	7	stabilized	stabilize	VBN
cord-342419-liaihahj	44	8	in	in	IN
cord-342419-liaihahj	44	9	the	the	DT
cord-342419-liaihahj	44	10	prefusion	prefusion	NN
cord-342419-liaihahj	44	11	conformation	conformation	NN
cord-342419-liaihahj	44	12	using	use	VBG
cord-342419-liaihahj	44	13	cysteine	cysteine	NN
cord-342419-liaihahj	44	14	substitutions	substitution	NNS
cord-342419-liaihahj	44	15	to	to	TO
cord-342419-liaihahj	44	16	lock	lock	VB
cord-342419-liaihahj	44	17	the	the	DT
cord-342419-liaihahj	44	18	protein	protein	NN
cord-342419-liaihahj	44	19	in	in	IN
cord-342419-liaihahj	44	20	the	the	DT
cord-342419-liaihahj	44	21	pre	pre	JJ
cord-342419-liaihahj	44	22	-	-	JJ
cord-342419-liaihahj	44	23	fusion	fusion	JJ
cord-342419-liaihahj	44	24	state	state	NN
cord-342419-liaihahj	44	25	by	by	IN
cord-342419-liaihahj	44	26	disulfide	disulfide	JJ
cord-342419-liaihahj	44	27	bonds	bond	NNS
cord-342419-liaihahj	44	28	,	,	,
cord-342419-liaihahj	44	29	and	and	CC
cord-342419-liaihahj	44	30	through	through	IN
cord-342419-liaihahj	44	31	cavity	cavity	NN
cord-342419-liaihahj	44	32	-	-	HYPH
cord-342419-liaihahj	44	33	filling	fill	VBG
cord-342419-liaihahj	44	34	mutations	mutation	NNS
cord-342419-liaihahj	44	35	to	to	TO
cord-342419-liaihahj	44	36	prevent	prevent	VB
cord-342419-liaihahj	44	37	transition	transition	NN
cord-342419-liaihahj	44	38	to	to	IN
cord-342419-liaihahj	44	39	the	the	DT
cord-342419-liaihahj	44	40	post	post	JJ
cord-342419-liaihahj	44	41	-	-	JJ
cord-342419-liaihahj	44	42	fusion	fusion	JJ
cord-342419-liaihahj	44	43	state	state	NN
cord-342419-liaihahj	44	44	.	.	.
cord-342419-liaihahj	45	1	This	this	DT
cord-342419-liaihahj	45	2	Ds	Ds	NNP
cord-342419-liaihahj	45	3	-	-	HYPH
cord-342419-liaihahj	45	4	Cav1	Cav1	NNP
cord-342419-liaihahj	45	5	construct	construct	NN
cord-342419-liaihahj	45	6	has	have	VBZ
cord-342419-liaihahj	45	7	been	be	VBN
cord-342419-liaihahj	45	8	further	further	RB
cord-342419-liaihahj	45	9	developed	develop	VBN
cord-342419-liaihahj	45	10	for	for	IN
cord-342419-liaihahj	45	11	clinical	clinical	JJ
cord-342419-liaihahj	45	12	trials	trial	NNS
cord-342419-liaihahj	45	13	,	,	,
cord-342419-liaihahj	45	14	and	and	CC
cord-342419-liaihahj	45	15	has	have	VBZ
cord-342419-liaihahj	45	16	shown	show	VBN
cord-342419-liaihahj	45	17	promise	promise	NN
cord-342419-liaihahj	45	18	in	in	IN
cord-342419-liaihahj	45	19	a	a	DT
cord-342419-liaihahj	45	20	phase	phase	NN
cord-342419-liaihahj	45	21	I	-PRON-	PRP
cord-342419-liaihahj	45	22	clinical	clinical	JJ
cord-342419-liaihahj	45	23	trial	trial	NN
cord-342419-liaihahj	45	24	[	[	-LRB-
cord-342419-liaihahj	45	25	41	41	CD
cord-342419-liaihahj	45	26	]	]	-RRB-
cord-342419-liaihahj	45	27	.	.	.
cord-342419-liaihahj	46	1	Additional	additional	JJ
cord-342419-liaihahj	46	2	constructs	construct	NNS
cord-342419-liaihahj	46	3	for	for	IN
cord-342419-liaihahj	46	4	RSV	RSV	NNP
cord-342419-liaihahj	46	5	F	F	NNP
cord-342419-liaihahj	46	6	have	have	VBP
cord-342419-liaihahj	46	7	focused	focus	VBN
cord-342419-liaihahj	46	8	on	on	IN
cord-342419-liaihahj	46	9	stabilizing	stabilize	VBG
cord-342419-liaihahj	46	10	the	the	DT
cord-342419-liaihahj	46	11	α4-α5	α4-α5	NNP
cord-342419-liaihahj	46	12	loop	loop	VB
cord-342419-liaihahj	46	13	through	through	IN
cord-342419-liaihahj	46	14	proline	proline	NN
cord-342419-liaihahj	46	15	mutations	mutation	NNS
cord-342419-liaihahj	46	16	[	[	-LRB-
cord-342419-liaihahj	46	17	40	40	CD
cord-342419-liaihahj	46	18	]	]	-RRB-
cord-342419-liaihahj	46	19	.	.	.
cord-342419-liaihahj	47	1	A	a	DT
cord-342419-liaihahj	47	2	similar	similar	JJ
cord-342419-liaihahj	47	3	approach	approach	NN
cord-342419-liaihahj	47	4	was	be	VBD
cord-342419-liaihahj	47	5	undertaken	undertake	VBN
cord-342419-liaihahj	47	6	for	for	IN
cord-342419-liaihahj	47	7	the	the	DT
cord-342419-liaihahj	47	8	hMPV	hmpv	NN
cord-342419-liaihahj	47	9	F	F	NNP
cord-342419-liaihahj	47	10	protein	protein	NN
cord-342419-liaihahj	47	11	,	,	,
cord-342419-liaihahj	47	12	whereby	whereby	WRB
cord-342419-liaihahj	47	13	a	a	DT
cord-342419-liaihahj	47	14	A185P	A185P	NNP
cord-342419-liaihahj	47	15	mutation	mutation	NN
cord-342419-liaihahj	47	16	was	be	VBD
cord-342419-liaihahj	47	17	introduced	introduce	VBN
cord-342419-liaihahj	47	18	to	to	TO
cord-342419-liaihahj	47	19	stabilize	stabilize	VB
cord-342419-liaihahj	47	20	the	the	DT
cord-342419-liaihahj	47	21	pre	pre	JJ
cord-342419-liaihahj	47	22	-	-	JJ
cord-342419-liaihahj	47	23	fusion	fusion	JJ
cord-342419-liaihahj	47	24	conformation	conformation	NN
cord-342419-liaihahj	47	25	[	[	-LRB-
cord-342419-liaihahj	47	26	38	38	CD
cord-342419-liaihahj	47	27	]	]	-RRB-
cord-342419-liaihahj	47	28	.	.	.
cord-342419-liaihahj	48	1	The	the	DT
cord-342419-liaihahj	48	2	hMPV	hmpv	NN
cord-342419-liaihahj	48	3	F	F	NNP
cord-342419-liaihahj	48	4	protein	protein	NN
cord-342419-liaihahj	48	5	contains	contain	VBZ
cord-342419-liaihahj	48	6	a	a	DT
cord-342419-liaihahj	48	7	single	single	JJ
cord-342419-liaihahj	48	8	site	site	NN
cord-342419-liaihahj	48	9	that	that	WDT
cord-342419-liaihahj	48	10	is	be	VBZ
cord-342419-liaihahj	48	11	cleaved	cleave	VBN
cord-342419-liaihahj	48	12	to	to	TO
cord-342419-liaihahj	48	13	convert	convert	VB
cord-342419-liaihahj	48	14	the	the	DT
cord-342419-liaihahj	48	15	polypeptide	polypeptide	NN
cord-342419-liaihahj	48	16	F	f	NN
cord-342419-liaihahj	48	17	0	0	CD
cord-342419-liaihahj	48	18	protein	protein	NN
cord-342419-liaihahj	48	19	into	into	IN
cord-342419-liaihahj	48	20	the	the	DT
cord-342419-liaihahj	48	21	meta	meta	JJ
cord-342419-liaihahj	48	22	-	-	HYPH
cord-342419-liaihahj	48	23	stable	stable	JJ
cord-342419-liaihahj	48	24	disulfide	disulfide	NN
cord-342419-liaihahj	48	25	-	-	HYPH
cord-342419-liaihahj	48	26	linked	link	VBN
cord-342419-liaihahj	48	27	F	F	NNP
cord-342419-liaihahj	48	28	1	1	CD
cord-342419-liaihahj	48	29	-F	-f	SYM
cord-342419-liaihahj	48	30	2	2	CD
cord-342419-liaihahj	48	31	pre	pre	JJ
cord-342419-liaihahj	48	32	-	-	JJ
cord-342419-liaihahj	48	33	fusion	fusion	JJ
cord-342419-liaihahj	48	34	homotrimer	homotrimer	NN
cord-342419-liaihahj	48	35	.	.	.
cord-342419-liaihahj	49	1	This	this	DT
cord-342419-liaihahj	49	2	is	be	VBZ
cord-342419-liaihahj	49	3	in	in	IN
cord-342419-liaihahj	49	4	contrast	contrast	NN
cord-342419-liaihahj	49	5	to	to	IN
cord-342419-liaihahj	49	6	RSV	RSV	NNP
cord-342419-liaihahj	49	7	F	F	NNP
cord-342419-liaihahj	49	8	,	,	,
cord-342419-liaihahj	49	9	which	which	WDT
cord-342419-liaihahj	49	10	contains	contain	VBZ
cord-342419-liaihahj	49	11	two	two	CD
cord-342419-liaihahj	49	12	furin	furin	NN
cord-342419-liaihahj	49	13	cleavage	cleavage	NN
cord-342419-liaihahj	49	14	sites	site	NNS
cord-342419-liaihahj	49	15	flanking	flank	VBG
cord-342419-liaihahj	49	16	the	the	DT
cord-342419-liaihahj	49	17	p27	p27	NN
cord-342419-liaihahj	49	18	peptide	peptide	NN
cord-342419-liaihahj	49	19	fragment	fragment	NN
cord-342419-liaihahj	49	20	.	.	.
cord-342419-liaihahj	50	1	The	the	DT
cord-342419-liaihahj	50	2	cleavage	cleavage	NN
cord-342419-liaihahj	50	3	enzyme	enzyme	NN
cord-342419-liaihahj	50	4	for	for	IN
cord-342419-liaihahj	50	5	hMPV	hmpv	NN
cord-342419-liaihahj	50	6	F	F	NNP
cord-342419-liaihahj	50	7	in	in	IN
cord-342419-liaihahj	50	8	vivo	vivo	NNP
cord-342419-liaihahj	50	9	is	be	VBZ
cord-342419-liaihahj	50	10	currently	currently	RB
cord-342419-liaihahj	50	11	unknown	unknown	JJ
cord-342419-liaihahj	50	12	,	,	,
cord-342419-liaihahj	50	13	although	although	IN
cord-342419-liaihahj	50	14	cleavage	cleavage	NN
cord-342419-liaihahj	50	15	can	can	MD
cord-342419-liaihahj	50	16	be	be	VB
cord-342419-liaihahj	50	17	accomplished	accomplish	VBN
cord-342419-liaihahj	50	18	by	by	IN
cord-342419-liaihahj	50	19	trypsin	trypsin	NN
cord-342419-liaihahj	50	20	in	in	IN
cord-342419-liaihahj	50	21	vitro	vitro	FW
cord-342419-liaihahj	50	22	[	[	-LRB-
cord-342419-liaihahj	50	23	42	42	CD
cord-342419-liaihahj	50	24	]	]	-RRB-
cord-342419-liaihahj	50	25	.	.	.
cord-342419-liaihahj	51	1	Post	post	JJ
cord-342419-liaihahj	51	2	-	-	JJ
cord-342419-liaihahj	51	3	fusion	fusion	NN
cord-342419-liaihahj	51	4	hMPV	hmpv	NN
cord-342419-liaihahj	51	5	F	F	NNP
cord-342419-liaihahj	51	6	has	have	VBZ
cord-342419-liaihahj	51	7	been	be	VBN
cord-342419-liaihahj	51	8	generated	generate	VBN
cord-342419-liaihahj	51	9	by	by	IN
cord-342419-liaihahj	51	10	removing	remove	VBG
cord-342419-liaihahj	51	11	the	the	DT
cord-342419-liaihahj	51	12	fusion	fusion	NN
cord-342419-liaihahj	51	13	peptide	peptide	NN
cord-342419-liaihahj	51	14	and	and	CC
cord-342419-liaihahj	51	15	incorporating	incorporate	VBG
cord-342419-liaihahj	51	16	one	one	CD
cord-342419-liaihahj	51	17	furin	furin	NN
cord-342419-liaihahj	51	18	cleavage	cleavage	NN
cord-342419-liaihahj	51	19	site	site	NN
cord-342419-liaihahj	51	20	from	from	IN
cord-342419-liaihahj	51	21	RSV	RSV	NNP
cord-342419-liaihahj	51	22	F	F	NNP
cord-342419-liaihahj	51	23	[	[	-LRB-
cord-342419-liaihahj	51	24	43	43	CD
cord-342419-liaihahj	51	25	]	]	-RRB-
cord-342419-liaihahj	51	26	.	.	.
cord-342419-liaihahj	52	1	X	x	NN
cord-342419-liaihahj	52	2	-	-	NN
cord-342419-liaihahj	52	3	ray	ray	NN
cord-342419-liaihahj	52	4	crystal	crystal	NN
cord-342419-liaihahj	52	5	structures	structure	NNS
cord-342419-liaihahj	52	6	of	of	IN
cord-342419-liaihahj	52	7	the	the	DT
cord-342419-liaihahj	52	8	hMPV	hmpv	NN
cord-342419-liaihahj	52	9	F	F	NNP
cord-342419-liaihahj	52	10	protein	protein	NN
cord-342419-liaihahj	52	11	from	from	IN
cord-342419-liaihahj	52	12	the	the	DT
cord-342419-liaihahj	52	13	A1	A1	NNP
cord-342419-liaihahj	52	14	subgroup	subgroup	NN
cord-342419-liaihahj	52	15	have	have	VBP
cord-342419-liaihahj	52	16	been	be	VBN
cord-342419-liaihahj	52	17	determined	determine	VBN
cord-342419-liaihahj	52	18	in	in	IN
cord-342419-liaihahj	52	19	the	the	DT
cord-342419-liaihahj	52	20	pre	pre	JJ
cord-342419-liaihahj	52	21	-	-	JJ
cord-342419-liaihahj	52	22	fusion	fusion	NN
cord-342419-liaihahj	52	23	and	and	CC
cord-342419-liaihahj	52	24	postfusion	postfusion	NN
cord-342419-liaihahj	52	25	conformations	conformation	NNS
cord-342419-liaihahj	52	26	[	[	-LRB-
cord-342419-liaihahj	52	27	38	38	CD
cord-342419-liaihahj	52	28	,	,	,
cord-342419-liaihahj	52	29	43	43	CD
cord-342419-liaihahj	52	30	]	]	-RRB-
cord-342419-liaihahj	52	31	.	.	.
cord-342419-liaihahj	53	1	Both	both	DT
cord-342419-liaihahj	53	2	proteins	protein	NNS
cord-342419-liaihahj	53	3	were	be	VBD
cord-342419-liaihahj	53	4	expressed	express	VBN
cord-342419-liaihahj	53	5	in	in	IN
cord-342419-liaihahj	53	6	CV-1	CV-1	NNP
cord-342419-liaihahj	53	7	cells	cell	NNS
cord-342419-liaihahj	53	8	using	use	VBG
cord-342419-liaihahj	53	9	a	a	DT
cord-342419-liaihahj	53	10	vaccinia	vaccinia	NN
cord-342419-liaihahj	53	11	virus	virus	NN
cord-342419-liaihahj	53	12	expression	expression	NN
cord-342419-liaihahj	53	13	system	system	NN
cord-342419-liaihahj	53	14	,	,	,
cord-342419-liaihahj	53	15	although	although	IN
cord-342419-liaihahj	53	16	stabilized	stabilize	VBD
cord-342419-liaihahj	53	17	versions	version	NNS
cord-342419-liaihahj	53	18	for	for	IN
cord-342419-liaihahj	53	19	routine	routine	JJ
cord-342419-liaihahj	53	20	HEK293F	HEK293F	NNP
cord-342419-liaihahj	53	21	or	or	CC
cord-342419-liaihahj	53	22	CHO	CHO	NNP
cord-342419-liaihahj	53	23	cell	cell	NN
cord-342419-liaihahj	53	24	line	line	NN
cord-342419-liaihahj	53	25	expression	expression	NN
cord-342419-liaihahj	53	26	have	have	VBP
cord-342419-liaihahj	53	27	not	not	RB
cord-342419-liaihahj	53	28	yet	yet	RB
cord-342419-liaihahj	53	29	been	be	VBN
cord-342419-liaihahj	53	30	generated	generate	VBN
cord-342419-liaihahj	53	31	.	.	.
cord-342419-liaihahj	54	1	For	for	IN
cord-342419-liaihahj	54	2	RSV	RSV	NNP
cord-342419-liaihahj	54	3	F	F	NNP
cord-342419-liaihahj	54	4	,	,	,
cord-342419-liaihahj	54	5	the	the	DT
cord-342419-liaihahj	54	6	pre	pre	JJ
cord-342419-liaihahj	54	7	-	-	JJ
cord-342419-liaihahj	54	8	fusion	fusion	JJ
cord-342419-liaihahj	54	9	conformation	conformation	NN
cord-342419-liaihahj	54	10	contains	contain	VBZ
cord-342419-liaihahj	54	11	antigenic	antigenic	JJ
cord-342419-liaihahj	54	12	sites	site	NNS
cord-342419-liaihahj	54	13	Ø	ø	NN
cord-342419-liaihahj	54	14	[	[	-LRB-
cord-342419-liaihahj	54	15	44	44	CD
cord-342419-liaihahj	54	16	]	]	-RRB-
cord-342419-liaihahj	54	17	and	and	CC
cord-342419-liaihahj	54	18	V	v	NN
cord-342419-liaihahj	54	19	[	[	-LRB-
cord-342419-liaihahj	54	20	45	45	CD
cord-342419-liaihahj	54	21	]	]	-RRB-
cord-342419-liaihahj	54	22	located	locate	VBN
cord-342419-liaihahj	54	23	on	on	IN
cord-342419-liaihahj	54	24	the	the	DT
cord-342419-liaihahj	54	25	head	head	NN
cord-342419-liaihahj	54	26	of	of	IN
cord-342419-liaihahj	54	27	the	the	DT
cord-342419-liaihahj	54	28	RSV	RSV	NNP
cord-342419-liaihahj	54	29	F	F	NNP
cord-342419-liaihahj	54	30	protein	protein	NN
cord-342419-liaihahj	54	31	,	,	,
cord-342419-liaihahj	54	32	which	which	WDT
cord-342419-liaihahj	54	33	elicit	elicit	VBP
cord-342419-liaihahj	54	34	a	a	DT
cord-342419-liaihahj	54	35	more	more	RBR
cord-342419-liaihahj	54	36	potent	potent	JJ
cord-342419-liaihahj	54	37	neutralizing	neutralize	VBG
cord-342419-liaihahj	54	38	antibody	antibody	NN
cord-342419-liaihahj	54	39	response	response	NN
cord-342419-liaihahj	54	40	as	as	IN
cord-342419-liaihahj	54	41	compared	compare	VBN
cord-342419-liaihahj	54	42	to	to	IN
cord-342419-liaihahj	54	43	the	the	DT
cord-342419-liaihahj	54	44	post	post	JJ
cord-342419-liaihahj	54	45	-	-	JJ
cord-342419-liaihahj	54	46	fusion	fusion	JJ
cord-342419-liaihahj	54	47	conformation	conformation	NN
cord-342419-liaihahj	54	48	[	[	-LRB-
cord-342419-liaihahj	54	49	44	44	CD
cord-342419-liaihahj	54	50	,	,	,
cord-342419-liaihahj	54	51	45	45	CD
cord-342419-liaihahj	54	52	]	]	-RRB-
cord-342419-liaihahj	54	53	.	.	.
cord-342419-liaihahj	55	1	Furthermore	furthermore	RB
cord-342419-liaihahj	55	2	,	,	,
cord-342419-liaihahj	55	3	the	the	DT
cord-342419-liaihahj	55	4	human	human	JJ
cord-342419-liaihahj	55	5	antibody	antibody	NN
cord-342419-liaihahj	55	6	response	response	NN
cord-342419-liaihahj	55	7	to	to	IN
cord-342419-liaihahj	55	8	RSV	RSV	NNP
cord-342419-liaihahj	55	9	infection	infection	NN
cord-342419-liaihahj	55	10	is	be	VBZ
cord-342419-liaihahj	55	11	primarily	primarily	RB
cord-342419-liaihahj	55	12	focused	focus	VBN
cord-342419-liaihahj	55	13	on	on	IN
cord-342419-liaihahj	55	14	these	these	DT
cord-342419-liaihahj	55	15	pre	pre	JJ
cord-342419-liaihahj	55	16	-	-	JJ
cord-342419-liaihahj	55	17	fusion	fusion	JJ
cord-342419-liaihahj	55	18	-	-	HYPH
cord-342419-liaihahj	55	19	specific	specific	JJ
cord-342419-liaihahj	55	20	epitopes	epitope	NNS
cord-342419-liaihahj	55	21	[	[	-LRB-
cord-342419-liaihahj	55	22	46	46	CD
cord-342419-liaihahj	55	23	]	]	-RRB-
cord-342419-liaihahj	55	24	.	.	.
cord-342419-liaihahj	56	1	For	for	IN
cord-342419-liaihahj	56	2	hMPV	hmpv	NN
cord-342419-liaihahj	56	3	F	F	NNP
cord-342419-liaihahj	56	4	,	,	,
cord-342419-liaihahj	56	5	data	datum	NNS
cord-342419-liaihahj	56	6	using	use	VBG
cord-342419-liaihahj	56	7	human	human	JJ
cord-342419-liaihahj	56	8	serum	serum	NN
cord-342419-liaihahj	56	9	has	have	VBZ
cord-342419-liaihahj	56	10	shown	show	VBN
cord-342419-liaihahj	56	11	that	that	IN
cord-342419-liaihahj	56	12	the	the	DT
cord-342419-liaihahj	56	13	preponderance	preponderance	NN
cord-342419-liaihahj	56	14	of	of	IN
cord-342419-liaihahj	56	15	hMPV	hmpv	NN
cord-342419-liaihahj	56	16	F	F	NNP
cord-342419-liaihahj	56	17	-	-	HYPH
cord-342419-liaihahj	56	18	specific	specific	JJ
cord-342419-liaihahj	56	19	human	human	JJ
cord-342419-liaihahj	56	20	antibodies	antibody	NNS
cord-342419-liaihahj	56	21	bind	bind	VBP
cord-342419-liaihahj	56	22	both	both	DT
cord-342419-liaihahj	56	23	pre	pre	JJ
cord-342419-liaihahj	56	24	-	-	JJ
cord-342419-liaihahj	56	25	fusion	fusion	JJ
cord-342419-liaihahj	56	26	and	and	CC
cord-342419-liaihahj	56	27	post	post	JJ
cord-342419-liaihahj	56	28	-	-	JJ
cord-342419-liaihahj	56	29	fusion	fusion	JJ
cord-342419-liaihahj	56	30	F	F	NNP
cord-342419-liaihahj	56	31	conformations	conformation	NNS
cord-342419-liaihahj	56	32	,	,	,
cord-342419-liaihahj	56	33	which	which	WDT
cord-342419-liaihahj	56	34	has	have	VBZ
cord-342419-liaihahj	56	35	been	be	VBN
cord-342419-liaihahj	56	36	proposed	propose	VBN
cord-342419-liaihahj	56	37	is	be	VBZ
cord-342419-liaihahj	56	38	due	due	JJ
cord-342419-liaihahj	56	39	to	to	IN
cord-342419-liaihahj	56	40	differential	differential	JJ
cord-342419-liaihahj	56	41	glycan	glycan	NN
cord-342419-liaihahj	56	42	positioning	positioning	NN
cord-342419-liaihahj	56	43	on	on	IN
cord-342419-liaihahj	56	44	the	the	DT
cord-342419-liaihahj	56	45	head	head	NN
cord-342419-liaihahj	56	46	of	of	IN
cord-342419-liaihahj	56	47	the	the	DT
cord-342419-liaihahj	56	48	hMPV	hmpv	NN
cord-342419-liaihahj	56	49	F	F	NNP
cord-342419-liaihahj	56	50	protein	protein	NN
cord-342419-liaihahj	56	51	as	as	IN
cord-342419-liaihahj	56	52	compared	compare	VBN
cord-342419-liaihahj	56	53	to	to	IN
cord-342419-liaihahj	56	54	the	the	DT
cord-342419-liaihahj	56	55	RSV	RSV	NNP
cord-342419-liaihahj	56	56	F	F	NNP
cord-342419-liaihahj	56	57	protein	protein	NN
cord-342419-liaihahj	56	58	[	[	-LRB-
cord-342419-liaihahj	56	59	38	38	CD
cord-342419-liaihahj	56	60	]	]	-RRB-
cord-342419-liaihahj	56	61	.	.	.
cord-342419-liaihahj	57	1	Although	although	IN
cord-342419-liaihahj	57	2	several	several	JJ
cord-342419-liaihahj	57	3	monoclonal	monoclonal	JJ
cord-342419-liaihahj	57	4	antibodies	antibody	NNS
cord-342419-liaihahj	57	5	(	(	-LRB-
cord-342419-liaihahj	57	6	mAbs	mAbs	NNP
cord-342419-liaihahj	57	7	)	)	-RRB-
cord-342419-liaihahj	57	8	have	have	VBP
cord-342419-liaihahj	57	9	previously	previously	RB
cord-342419-liaihahj	57	10	been	be	VBN
cord-342419-liaihahj	57	11	isolated	isolate	VBN
cord-342419-liaihahj	57	12	that	that	WDT
cord-342419-liaihahj	57	13	recognize	recognize	VBP
cord-342419-liaihahj	57	14	the	the	DT
cord-342419-liaihahj	57	15	hMPV	hmpv	NN
cord-342419-liaihahj	57	16	F	F	NNP
cord-342419-liaihahj	57	17	protein	protein	NN
cord-342419-liaihahj	57	18	[	[	-LRB-
cord-342419-liaihahj	57	19	43	43	CD
cord-342419-liaihahj	57	20	,	,	,
cord-342419-liaihahj	57	21	[	[	-LRB-
cord-342419-liaihahj	57	22	47	47	CD
cord-342419-liaihahj	57	23	]	]	-RRB-
cord-342419-liaihahj	57	24	[	[	-LRB-
cord-342419-liaihahj	57	25	48	48	CD
cord-342419-liaihahj	57	26	]	]	-RRB-
cord-342419-liaihahj	57	27	[	[	-LRB-
cord-342419-liaihahj	57	28	49	49	CD
cord-342419-liaihahj	57	29	]	]	-RRB-
cord-342419-liaihahj	57	30	[	[	-LRB-
cord-342419-liaihahj	57	31	50	50	CD
cord-342419-liaihahj	57	32	]	]	-RRB-
cord-342419-liaihahj	57	33	[	[	-LRB-
cord-342419-liaihahj	57	34	51	51	CD
cord-342419-liaihahj	57	35	]	]	-RRB-
cord-342419-liaihahj	57	36	[	[	-LRB-
cord-342419-liaihahj	57	37	52	52	CD
cord-342419-liaihahj	57	38	]	]	-RRB-
cord-342419-liaihahj	57	39	[	[	-LRB-
cord-342419-liaihahj	57	40	53	53	CD
cord-342419-liaihahj	57	41	]	]	-RRB-
cord-342419-liaihahj	57	42	[	[	-LRB-
cord-342419-liaihahj	57	43	54	54	CD
cord-342419-liaihahj	57	44	]	]	-RRB-
cord-342419-liaihahj	57	45	,	,	,
cord-342419-liaihahj	57	46	the	the	DT
cord-342419-liaihahj	57	47	predominant	predominant	JJ
cord-342419-liaihahj	57	48	antigenic	antigenic	JJ
cord-342419-liaihahj	57	49	sites	site	NNS
cord-342419-liaihahj	57	50	targeted	target	VBN
cord-342419-liaihahj	57	51	by	by	IN
cord-342419-liaihahj	57	52	the	the	DT
cord-342419-liaihahj	57	53	human	human	JJ
cord-342419-liaihahj	57	54	antibody	antibody	NN
cord-342419-liaihahj	57	55	response	response	NN
cord-342419-liaihahj	57	56	are	be	VBP
cord-342419-liaihahj	57	57	unclear	unclear	JJ
cord-342419-liaihahj	57	58	.	.	.
cord-342419-liaihahj	58	1	A	a	DT
cord-342419-liaihahj	58	2	panel	panel	NN
cord-342419-liaihahj	58	3	of	of	IN
cord-342419-liaihahj	58	4	rodent	rodent	NN
cord-342419-liaihahj	58	5	-	-	HYPH
cord-342419-liaihahj	58	6	derived	derive	VBN
cord-342419-liaihahj	58	7	mAbs	mAbs	NNP
cord-342419-liaihahj	58	8	was	be	VBD
cord-342419-liaihahj	58	9	initially	initially	RB
cord-342419-liaihahj	58	10	used	use	VBN
cord-342419-liaihahj	58	11	to	to	TO
cord-342419-liaihahj	58	12	map	map	VB
cord-342419-liaihahj	58	13	the	the	DT
cord-342419-liaihahj	58	14	neutralizing	neutralize	VBG
cord-342419-liaihahj	58	15	epitopes	epitope	NNS
cord-342419-liaihahj	58	16	on	on	IN
cord-342419-liaihahj	58	17	the	the	DT
cord-342419-liaihahj	58	18	hMPV	hmpv	NN
cord-342419-liaihahj	58	19	F	F	NNP
cord-342419-liaihahj	58	20	protein	protein	NN
cord-342419-liaihahj	58	21	using	use	VBG
cord-342419-liaihahj	58	22	viral	viral	JJ
cord-342419-liaihahj	58	23	escape	escape	NN
cord-342419-liaihahj	58	24	mutants	mutant	NNS
cord-342419-liaihahj	58	25	[	[	-LRB-
cord-342419-liaihahj	58	26	47	47	CD
cord-342419-liaihahj	58	27	,	,	,
cord-342419-liaihahj	58	28	48	48	CD
cord-342419-liaihahj	58	29	]	]	-RRB-
cord-342419-liaihahj	58	30	.	.	.
cord-342419-liaihahj	59	1	The	the	DT
cord-342419-liaihahj	59	2	known	known	JJ
cord-342419-liaihahj	59	3	antigenic	antigenic	JJ
cord-342419-liaihahj	59	4	sites	site	NNS
cord-342419-liaihahj	59	5	on	on	IN
cord-342419-liaihahj	59	6	the	the	DT
cord-342419-liaihahj	59	7	hMPV	hmpv	NN
cord-342419-liaihahj	59	8	F	F	NNP
cord-342419-liaihahj	59	9	protein	protein	NN
cord-342419-liaihahj	59	10	include	include	VBP
cord-342419-liaihahj	59	11	antigenic	antigenic	JJ
cord-342419-liaihahj	59	12	sites	site	NNS
cord-342419-liaihahj	59	13	III	III	NNP
cord-342419-liaihahj	59	14	,	,	,
cord-342419-liaihahj	59	15	IV	IV	NNP
cord-342419-liaihahj	59	16	,	,	,
cord-342419-liaihahj	59	17	and	and	CC
cord-342419-liaihahj	59	18	an	an	DT
cord-342419-liaihahj	59	19	unnamed	unnamed	JJ
cord-342419-liaihahj	59	20	site	site	NN
cord-342419-liaihahj	59	21	targeted	target	VBN
cord-342419-liaihahj	59	22	by	by	IN
cord-342419-liaihahj	59	23	mAb	mab	NN
cord-342419-liaihahj	59	24	DS7	ds7	NN
cord-342419-liaihahj	59	25	[	[	-LRB-
cord-342419-liaihahj	59	26	35	35	CD
cord-342419-liaihahj	59	27	]	]	-RRB-
cord-342419-liaihahj	59	28	.	.	.
cord-342419-liaihahj	60	1	DS7	DS7	NNP
cord-342419-liaihahj	60	2	was	be	VBD
cord-342419-liaihahj	60	3	isolated	isolate	VBN
cord-342419-liaihahj	60	4	from	from	IN
cord-342419-liaihahj	60	5	a	a	DT
cord-342419-liaihahj	60	6	human	human	JJ
cord-342419-liaihahj	60	7	phage	phage	NN
cord-342419-liaihahj	60	8	display	display	NN
cord-342419-liaihahj	60	9	library	library	NN
cord-342419-liaihahj	60	10	[	[	-LRB-
cord-342419-liaihahj	60	11	49	49	CD
cord-342419-liaihahj	60	12	]	]	-RRB-
cord-342419-liaihahj	60	13	,	,	,
cord-342419-liaihahj	60	14	and	and	CC
cord-342419-liaihahj	60	15	was	be	VBD
cord-342419-liaihahj	60	16	co	co	JJ
cord-342419-liaihahj	60	17	-	-	VBN
cord-342419-liaihahj	60	18	crystallized	crystallize	VBN
cord-342419-liaihahj	60	19	with	with	IN
cord-342419-liaihahj	60	20	a	a	DT
cord-342419-liaihahj	60	21	fragment	fragment	NN
cord-342419-liaihahj	60	22	of	of	IN
cord-342419-liaihahj	60	23	the	the	DT
cord-342419-liaihahj	60	24	pre	pre	JJ
cord-342419-liaihahj	60	25	-	-	JJ
cord-342419-liaihahj	60	26	fusion	fusion	JJ
cord-342419-liaihahj	60	27	hMPV	hmpv	NN
cord-342419-liaihahj	60	28	F	F	NNP
cord-342419-liaihahj	60	29	protein	protein	NN
cord-342419-liaihahj	60	30	[	[	-LRB-
cord-342419-liaihahj	60	31	55	55	CD
cord-342419-liaihahj	60	32	]	]	-RRB-
cord-342419-liaihahj	60	33	.	.	.
cord-342419-liaihahj	61	1	Several	several	JJ
cord-342419-liaihahj	61	2	mAbs	mabs	NN
cord-342419-liaihahj	61	3	isolated	isolate	VBN
cord-342419-liaihahj	61	4	have	have	VBP
cord-342419-liaihahj	61	5	been	be	VBN
cord-342419-liaihahj	61	6	found	find	VBN
cord-342419-liaihahj	61	7	to	to	TO
cord-342419-liaihahj	61	8	cross	cross	VB
cord-342419-liaihahj	61	9	-	-	VB
cord-342419-liaihahj	61	10	neutralize	neutralize	VB
cord-342419-liaihahj	61	11	RSV	RSV	NNP
cord-342419-liaihahj	61	12	and	and	CC
cord-342419-liaihahj	61	13	hMPV	hmpv	NN
cord-342419-liaihahj	61	14	,	,	,
cord-342419-liaihahj	61	15	including	include	VBG
cord-342419-liaihahj	61	16	MPE8	MPE8	NNP
cord-342419-liaihahj	61	17	[	[	-LRB-
cord-342419-liaihahj	61	18	51	51	CD
cord-342419-liaihahj	61	19	]	]	-RRB-
cord-342419-liaihahj	61	20	and	and	CC
cord-342419-liaihahj	61	21	25P13	25p13	LS
cord-342419-liaihahj	61	22	[	[	-LRB-
cord-342419-liaihahj	61	23	52	52	CD
cord-342419-liaihahj	61	24	]	]	-RRB-
cord-342419-liaihahj	61	25	(	(	-LRB-
cord-342419-liaihahj	61	26	site	site	NN
cord-342419-liaihahj	61	27	III	iii	CD
cord-342419-liaihahj	61	28	)	)	-RRB-
cord-342419-liaihahj	61	29	,	,	,
cord-342419-liaihahj	61	30	and	and	CC
cord-342419-liaihahj	61	31	101F	101f	CD
cord-342419-liaihahj	61	32	[	[	-LRB-
cord-342419-liaihahj	61	33	43	43	CD
cord-342419-liaihahj	61	34	]	]	-RRB-
cord-342419-liaihahj	61	35	,	,	,
cord-342419-liaihahj	61	36	54G10	54g10	CD
cord-342419-liaihahj	61	37	[	[	-LRB-
cord-342419-liaihahj	61	38	50	50	CD
cord-342419-liaihahj	61	39	]	]	-RRB-
cord-342419-liaihahj	61	40	,	,	,
cord-342419-liaihahj	61	41	and	and	CC
cord-342419-liaihahj	61	42	17E10	17e10	CD
cord-342419-liaihahj	61	43	[	[	-LRB-
cord-342419-liaihahj	61	44	53	53	CD
cord-342419-liaihahj	61	45	]	]	-RRB-
cord-342419-liaihahj	61	46	(	(	-LRB-
cord-342419-liaihahj	61	47	site	site	NN
cord-342419-liaihahj	61	48	IV	IV	NNP
cord-342419-liaihahj	61	49	)	)	-RRB-
cord-342419-liaihahj	61	50	.	.	.
cord-342419-liaihahj	62	1	In	in	IN
cord-342419-liaihahj	62	2	addition	addition	NN
cord-342419-liaihahj	62	3	,	,	,
cord-342419-liaihahj	62	4	we	-PRON-	PRP
cord-342419-liaihahj	62	5	have	have	VBP
cord-342419-liaihahj	62	6	recently	recently	RB
cord-342419-liaihahj	62	7	isolated	isolate	VBN
cord-342419-liaihahj	62	8	a	a	DT
cord-342419-liaihahj	62	9	panel	panel	NN
cord-342419-liaihahj	62	10	of	of	IN
cord-342419-liaihahj	62	11	human	human	NNP
cord-342419-liaihahj	62	12	mAbs	mAbs	NNP
cord-342419-liaihahj	62	13	targeting	target	VBG
cord-342419-liaihahj	62	14	site	site	NN
cord-342419-liaihahj	62	15	III	iii	CD
cord-342419-liaihahj	62	16	and	and	CC
cord-342419-liaihahj	62	17	the	the	DT
cord-342419-liaihahj	62	18	DS7	ds7	NN
cord-342419-liaihahj	62	19	epitope	epitope	NN
cord-342419-liaihahj	62	20	[	[	-LRB-
cord-342419-liaihahj	62	21	54	54	CD
cord-342419-liaihahj	62	22	]	]	-RRB-
cord-342419-liaihahj	62	23	.	.	.
cord-342419-liaihahj	63	1	One	one	CD
cord-342419-liaihahj	63	2	of	of	IN
cord-342419-liaihahj	63	3	these	these	DT
cord-342419-liaihahj	63	4	mAbs	mAbs	NNP
cord-342419-liaihahj	63	5	,	,	,
cord-342419-liaihahj	63	6	MPV364	MPV364	NNP
cord-342419-liaihahj	63	7	,	,	,
cord-342419-liaihahj	63	8	competes	compete	VBZ
cord-342419-liaihahj	63	9	for	for	IN
cord-342419-liaihahj	63	10	binding	bind	VBG
cord-342419-liaihahj	63	11	at	at	IN
cord-342419-liaihahj	63	12	antigenic	antigenic	JJ
cord-342419-liaihahj	63	13	site	site	NN
cord-342419-liaihahj	63	14	III	iii	CD
cord-342419-liaihahj	63	15	,	,	,
cord-342419-liaihahj	63	16	but	but	CC
cord-342419-liaihahj	63	17	does	do	VBZ
cord-342419-liaihahj	63	18	not	not	RB
cord-342419-liaihahj	63	19	cross	cross	VB
cord-342419-liaihahj	63	20	-	-	JJ
cord-342419-liaihahj	63	21	react	react	VB
cord-342419-liaihahj	63	22	with	with	IN
cord-342419-liaihahj	63	23	RSV	RSV	NNP
cord-342419-liaihahj	63	24	F	F	NNP
cord-342419-liaihahj	63	25	,	,	,
cord-342419-liaihahj	63	26	suggesting	suggest	VBG
cord-342419-liaihahj	63	27	closer	close	JJR
cord-342419-liaihahj	63	28	examination	examination	NN
cord-342419-liaihahj	63	29	of	of	IN
cord-342419-liaihahj	63	30	hMPV	hmpv	NN
cord-342419-liaihahj	63	31	F	F	NNP
cord-342419-liaihahj	63	32	epitopes	epitopes	NNP
cord-342419-liaihahj	63	33	is	be	VBZ
cord-342419-liaihahj	63	34	required	require	VBN
cord-342419-liaihahj	63	35	to	to	TO
cord-342419-liaihahj	63	36	improve	improve	VB
cord-342419-liaihahj	63	37	knowledge	knowledge	NN
cord-342419-liaihahj	63	38	on	on	IN
cord-342419-liaihahj	63	39	the	the	DT
cord-342419-liaihahj	63	40	optimal	optimal	JJ
cord-342419-liaihahj	63	41	epitopes	epitope	NNS
cord-342419-liaihahj	63	42	for	for	IN
cord-342419-liaihahj	63	43	elicitation	elicitation	NN
cord-342419-liaihahj	63	44	of	of	IN
cord-342419-liaihahj	63	45	neutralizing	neutralize	VBG
cord-342419-liaihahj	63	46	antibodies	antibody	NNS
cord-342419-liaihahj	63	47	.	.	.
cord-342419-liaihahj	64	1	In	in	IN
cord-342419-liaihahj	64	2	this	this	DT
cord-342419-liaihahj	64	3	study	study	NN
cord-342419-liaihahj	64	4	,	,	,
cord-342419-liaihahj	64	5	we	-PRON-	PRP
cord-342419-liaihahj	64	6	isolated	isolate	VBD
cord-342419-liaihahj	64	7	new	new	JJ
cord-342419-liaihahj	64	8	human	human	JJ
cord-342419-liaihahj	64	9	mAbs	mabs	NN
cord-342419-liaihahj	64	10	to	to	TO
cord-342419-liaihahj	64	11	further	further	RB
cord-342419-liaihahj	64	12	identify	identify	VB
cord-342419-liaihahj	64	13	the	the	DT
cord-342419-liaihahj	64	14	epitopes	epitope	NNS
cord-342419-liaihahj	64	15	on	on	IN
cord-342419-liaihahj	64	16	the	the	DT
cord-342419-liaihahj	64	17	hMPV	hmpv	NN
cord-342419-liaihahj	64	18	F	F	NNP
cord-342419-liaihahj	64	19	protein	protein	NN
cord-342419-liaihahj	64	20	recognized	recognize	VBN
cord-342419-liaihahj	64	21	by	by	IN
cord-342419-liaihahj	64	22	the	the	DT
cord-342419-liaihahj	64	23	human	human	JJ
cord-342419-liaihahj	64	24	immune	immune	NN
cord-342419-liaihahj	64	25	system	system	NN
cord-342419-liaihahj	64	26	.	.	.
cord-342419-liaihahj	65	1	In	in	IN
cord-342419-liaihahj	65	2	our	-PRON-	PRP$
cord-342419-liaihahj	65	3	efforts	effort	NNS
cord-342419-liaihahj	65	4	to	to	TO
cord-342419-liaihahj	65	5	identify	identify	VB
cord-342419-liaihahj	65	6	the	the	DT
cord-342419-liaihahj	65	7	major	major	JJ
cord-342419-liaihahj	65	8	antigenic	antigenic	JJ
cord-342419-liaihahj	65	9	epitopes	epitope	NNS
cord-342419-liaihahj	65	10	on	on	IN
cord-342419-liaihahj	65	11	the	the	DT
cord-342419-liaihahj	65	12	hMPV	hmpv	NN
cord-342419-liaihahj	65	13	F	F	NNP
cord-342419-liaihahj	65	14	protein	protein	NN
cord-342419-liaihahj	65	15	,	,	,
cord-342419-liaihahj	65	16	we	-PRON-	PRP
cord-342419-liaihahj	65	17	isolated	isolate	VBD
cord-342419-liaihahj	65	18	mAbs	mAbs	NNP
cord-342419-liaihahj	65	19	from	from	IN
cord-342419-liaihahj	65	20	human	human	JJ
cord-342419-liaihahj	65	21	subjects	subject	NNS
cord-342419-liaihahj	65	22	using	use	VBG
cord-342419-liaihahj	65	23	hybridoma	hybridoma	NN
cord-342419-liaihahj	65	24	technology	technology	NN
cord-342419-liaihahj	65	25	[	[	-LRB-
cord-342419-liaihahj	65	26	56	56	CD
cord-342419-liaihahj	65	27	]	]	-RRB-
cord-342419-liaihahj	65	28	.	.	.
cord-342419-liaihahj	66	1	As	as	IN
cord-342419-liaihahj	66	2	hMPV	hmpv	NN
cord-342419-liaihahj	66	3	infection	infection	NN
cord-342419-liaihahj	66	4	and	and	CC
cord-342419-liaihahj	66	5	exposure	exposure	NN
cord-342419-liaihahj	66	6	is	be	VBZ
cord-342419-liaihahj	66	7	not	not	RB
cord-342419-liaihahj	66	8	routinely	routinely	RB
cord-342419-liaihahj	66	9	tested	test	VBN
cord-342419-liaihahj	66	10	in	in	IN
cord-342419-liaihahj	66	11	patients	patient	NNS
cord-342419-liaihahj	66	12	,	,	,
cord-342419-liaihahj	66	13	and	and	CC
cord-342419-liaihahj	66	14	the	the	DT
cord-342419-liaihahj	66	15	majority	majority	NN
cord-342419-liaihahj	66	16	of	of	IN
cord-342419-liaihahj	66	17	individuals	individual	NNS
cord-342419-liaihahj	66	18	are	be	VBP
cord-342419-liaihahj	66	19	seropositive	seropositive	JJ
cord-342419-liaihahj	66	20	for	for	IN
cord-342419-liaihahj	66	21	hMPV	hmpv	NN
cord-342419-liaihahj	66	22	infection	infection	NN
cord-342419-liaihahj	66	23	[	[	-LRB-
cord-342419-liaihahj	66	24	57	57	CD
cord-342419-liaihahj	66	25	]	]	-RRB-
cord-342419-liaihahj	66	26	,	,	,
cord-342419-liaihahj	66	27	we	-PRON-	PRP
cord-342419-liaihahj	66	28	isolated	isolate	VBD
cord-342419-liaihahj	66	29	mAbs	mAbs	NNP
cord-342419-liaihahj	66	30	from	from	IN
cord-342419-liaihahj	66	31	two	two	CD
cord-342419-liaihahj	66	32	healthy	healthy	JJ
cord-342419-liaihahj	66	33	human	human	JJ
cord-342419-liaihahj	66	34	subjects	subject	NNS
cord-342419-liaihahj	66	35	.	.	.
cord-342419-liaihahj	67	1	Two	two	CD
cord-342419-liaihahj	67	2	new	new	JJ
cord-342419-liaihahj	67	3	mAbs	mAbs	NNP
cord-342419-liaihahj	67	4	were	be	VBD
cord-342419-liaihahj	67	5	isolated	isolate	VBN
cord-342419-liaihahj	67	6	against	against	IN
cord-342419-liaihahj	67	7	the	the	DT
cord-342419-liaihahj	67	8	recombinantly	recombinantly	NN
cord-342419-liaihahj	67	9	expressed	express	VBD
cord-342419-liaihahj	67	10	hMPV	hmpv	NN
cord-342419-liaihahj	67	11	B2	b2	NN
cord-342419-liaihahj	67	12	F	F	NNP
cord-342419-liaihahj	67	13	protein	protein	NN
cord-342419-liaihahj	67	14	(	(	-LRB-
cord-342419-liaihahj	67	15	S1	S1	NNP
cord-342419-liaihahj	67	16	Table	Table	NNP
cord-342419-liaihahj	67	17	)	)	-RRB-
cord-342419-liaihahj	67	18	expressed	express	VBD
cord-342419-liaihahj	67	19	in	in	IN
cord-342419-liaihahj	67	20	HEK293F	HEK293F	NNP
cord-342419-liaihahj	67	21	cells	cell	NNS
cord-342419-liaihahj	67	22	[	[	-LRB-
cord-342419-liaihahj	67	23	54	54	CD
cord-342419-liaihahj	67	24	]	]	-RRB-
cord-342419-liaihahj	67	25	.	.	.
cord-342419-liaihahj	68	1	MPV458	MPV458	NNP
cord-342419-liaihahj	68	2	and	and	CC
cord-342419-liaihahj	68	3	MPV465	MPV465	NNP
cord-342419-liaihahj	68	4	were	be	VBD
cord-342419-liaihahj	68	5	isolated	isolate	VBN
cord-342419-liaihahj	68	6	from	from	IN
cord-342419-liaihahj	68	7	two	two	CD
cord-342419-liaihahj	68	8	different	different	JJ
cord-342419-liaihahj	68	9	donors	donor	NNS
cord-342419-liaihahj	68	10	,	,	,
cord-342419-liaihahj	68	11	and	and	CC
cord-342419-liaihahj	68	12	have	have	VBP
cord-342419-liaihahj	68	13	isotypes	isotype	NNS
cord-342419-liaihahj	68	14	of	of	IN
cord-342419-liaihahj	68	15	IgG	IgG	NNP
cord-342419-liaihahj	68	16	3	3	CD
cord-342419-liaihahj	68	17	and	and	CC
cord-342419-liaihahj	68	18	kappa	kappa	NNP
cord-342419-liaihahj	68	19	,	,	,
cord-342419-liaihahj	68	20	and	and	CC
cord-342419-liaihahj	68	21	IgG	IgG	NNP
cord-342419-liaihahj	68	22	1	1	CD
cord-342419-liaihahj	68	23	and	and	CC
cord-342419-liaihahj	68	24	lambda	lambda	NNP
cord-342419-liaihahj	68	25	,	,	,
cord-342419-liaihahj	68	26	respectively	respectively	RB
cord-342419-liaihahj	68	27	.	.	.
cord-342419-liaihahj	69	1	MPV458	MPV458	NNP
cord-342419-liaihahj	69	2	utilizes	utilize	VBZ
cord-342419-liaihahj	69	3	V	V	NNP
cord-342419-liaihahj	69	4	H	H	NNP
cord-342419-liaihahj	69	5	3	3	CD
cord-342419-liaihahj	69	6	-	-	SYM
cord-342419-liaihahj	69	7	30	30	CD
cord-342419-liaihahj	69	8	,	,	,
cord-342419-liaihahj	69	9	J	J	NNP
cord-342419-liaihahj	69	10	H	H	NNP
cord-342419-liaihahj	69	11	3	3	CD
cord-342419-liaihahj	69	12	,	,	,
cord-342419-liaihahj	69	13	D	D	NNP
cord-342419-liaihahj	69	14	H	h	NN
cord-342419-liaihahj	69	15	2	2	CD
cord-342419-liaihahj	69	16	,	,	,
cord-342419-liaihahj	69	17	V	v	NN
cord-342419-liaihahj	69	18	K	K	NNP
cord-342419-liaihahj	69	19	1	1	CD
cord-342419-liaihahj	69	20	-	-	HYPH
cord-342419-liaihahj	69	21	33	33	CD
cord-342419-liaihahj	69	22	,	,	,
cord-342419-liaihahj	69	23	and	and	CC
cord-342419-liaihahj	69	24	J	J	NNP
cord-342419-liaihahj	69	25	K	K	NNP
cord-342419-liaihahj	69	26	5	5	CD
cord-342419-liaihahj	69	27	,	,	,
cord-342419-liaihahj	69	28	while	while	IN
cord-342419-liaihahj	69	29	MPV465	MPV465	NNP
cord-342419-liaihahj	69	30	utilizes	utilize	VBZ
cord-342419-liaihahj	69	31	V	V	NNP
cord-342419-liaihahj	69	32	H	H	NNP
cord-342419-liaihahj	69	33	3	3	CD
cord-342419-liaihahj	69	34	-	-	SYM
cord-342419-liaihahj	69	35	33	33	CD
cord-342419-liaihahj	69	36	,	,	,
cord-342419-liaihahj	69	37	J	J	NNP
cord-342419-liaihahj	69	38	H	H	NNP
cord-342419-liaihahj	69	39	5	5	CD
cord-342419-liaihahj	69	40	,	,	,
cord-342419-liaihahj	69	41	D	D	NNP
cord-342419-liaihahj	69	42	H	h	NN
cord-342419-liaihahj	69	43	3	3	CD
cord-342419-liaihahj	69	44	-	-	SYM
cord-342419-liaihahj	69	45	22	22	CD
cord-342419-liaihahj	69	46	,	,	,
cord-342419-liaihahj	69	47	V	V	NNP
cord-342419-liaihahj	69	48	L	L	NNP
cord-342419-liaihahj	69	49	-47	-47	NNP
cord-342419-liaihahj	69	50	,	,	,
cord-342419-liaihahj	69	51	and	and	CC
cord-342419-liaihahj	69	52	J	J	NNP
cord-342419-liaihahj	69	53	L	L	NNP
cord-342419-liaihahj	69	54	3	3	CD
cord-342419-liaihahj	69	55	.	.	.
cord-342419-liaihahj	70	1	The	the	DT
cord-342419-liaihahj	70	2	heavy	heavy	JJ
cord-342419-liaihahj	70	3	chain	chain	NN
cord-342419-liaihahj	70	4	complementarity	complementarity	NN
cord-342419-liaihahj	71	1	determining	determine	VBG
cord-342419-liaihahj	71	2	region	region	NN
cord-342419-liaihahj	71	3	(	(	-LRB-
cord-342419-liaihahj	71	4	HCDR	HCDR	NNP
cord-342419-liaihahj	71	5	)	)	-RRB-
cord-342419-liaihahj	71	6	3	3	CD
cord-342419-liaihahj	71	7	loop	loop	NN
cord-342419-liaihahj	71	8	length	length	NN
cord-342419-liaihahj	71	9	differs	differ	VBZ
cord-342419-liaihahj	71	10	dramatically	dramatically	RB
cord-342419-liaihahj	71	11	between	between	IN
cord-342419-liaihahj	71	12	the	the	DT
cord-342419-liaihahj	71	13	two	two	CD
cord-342419-liaihahj	71	14	mAbs	mabs	NN
cord-342419-liaihahj	71	15	as	as	IN
cord-342419-liaihahj	71	16	the	the	DT
cord-342419-liaihahj	71	17	HCDR3	HCDR3	NNS
cord-342419-liaihahj	71	18	loop	loop	VBP
cord-342419-liaihahj	71	19	for	for	IN
cord-342419-liaihahj	71	20	MPV458	MPV458	NNP
cord-342419-liaihahj	72	1	is	be	VBZ
cord-342419-liaihahj	72	2	just	just	RB
cord-342419-liaihahj	72	3	8	8	CD
cord-342419-liaihahj	72	4	amino	amino	NN
cord-342419-liaihahj	72	5	acids	acid	NNS
cord-342419-liaihahj	72	6	,	,	,
cord-342419-liaihahj	72	7	while	while	IN
cord-342419-liaihahj	72	8	MPV465	MPV465	NNP
cord-342419-liaihahj	72	9	has	have	VBZ
cord-342419-liaihahj	72	10	a	a	DT
cord-342419-liaihahj	72	11	21	21	CD
cord-342419-liaihahj	72	12	amino	amino	NN
cord-342419-liaihahj	72	13	acid	acid	NN
cord-342419-liaihahj	72	14	long	long	JJ
cord-342419-liaihahj	72	15	CDR3	CDR3	NNP
cord-342419-liaihahj	72	16	loop	loop	NN
cord-342419-liaihahj	72	17	(	(	-LRB-
cord-342419-liaihahj	72	18	S2	S2	NNP
cord-342419-liaihahj	72	19	Table	Table	NNP
cord-342419-liaihahj	72	20	)	)	-RRB-
cord-342419-liaihahj	72	21	.	.	.
cord-342419-liaihahj	73	1	To	to	TO
cord-342419-liaihahj	73	2	identify	identify	VB
cord-342419-liaihahj	73	3	the	the	DT
cord-342419-liaihahj	73	4	antigenic	antigenic	JJ
cord-342419-liaihahj	73	5	epitopes	epitope	NNS
cord-342419-liaihahj	73	6	targeted	target	VBN
cord-342419-liaihahj	73	7	by	by	IN
cord-342419-liaihahj	73	8	the	the	DT
cord-342419-liaihahj	73	9	isolated	isolate	VBN
cord-342419-liaihahj	73	10	mAbs	mAbs	NNP
cord-342419-liaihahj	73	11	,	,	,
cord-342419-liaihahj	73	12	we	-PRON-	PRP
cord-342419-liaihahj	73	13	performed	perform	VBD
cord-342419-liaihahj	73	14	epitope	epitope	NN
cord-342419-liaihahj	73	15	binning	binning	NN
cord-342419-liaihahj	73	16	using	use	VBG
cord-342419-liaihahj	73	17	competitive	competitive	JJ
cord-342419-liaihahj	73	18	biolayer	biolayer	NN
cord-342419-liaihahj	73	19	interferometry	interferometry	NN
cord-342419-liaihahj	73	20	[	[	-LRB-
cord-342419-liaihahj	73	21	58	58	CD
cord-342419-liaihahj	73	22	]	]	-RRB-
cord-342419-liaihahj	73	23	.	.	.
cord-342419-liaihahj	74	1	Previously	previously	RB
cord-342419-liaihahj	74	2	discovered	discover	VBD
cord-342419-liaihahj	74	3	mAbs	mAbs	NNP
cord-342419-liaihahj	74	4	with	with	IN
cord-342419-liaihahj	74	5	known	know	VBN
cord-342419-liaihahj	74	6	antigenic	antigenic	JJ
cord-342419-liaihahj	74	7	epitopes	epitope	NNS
cord-342419-liaihahj	74	8	were	be	VBD
cord-342419-liaihahj	74	9	utilized	utilize	VBN
cord-342419-liaihahj	74	10	as	as	IN
cord-342419-liaihahj	74	11	mapping	mapping	NN
cord-342419-liaihahj	74	12	controls	control	NNS
cord-342419-liaihahj	74	13	,	,	,
cord-342419-liaihahj	74	14	including	include	VBG
cord-342419-liaihahj	74	15	mAbs	mAbs	NNP
cord-342419-liaihahj	74	16	101F	101f	CD
cord-342419-liaihahj	74	17	[	[	-LRB-
cord-342419-liaihahj	74	18	59	59	CD
cord-342419-liaihahj	74	19	]	]	-RRB-
cord-342419-liaihahj	74	20	(	(	-LRB-
cord-342419-liaihahj	74	21	site	site	NN
cord-342419-liaihahj	74	22	IV	IV	NNP
cord-342419-liaihahj	74	23	)	)	-RRB-
cord-342419-liaihahj	74	24	,	,	.
cord-342419-liaihahj	75	1	MPV196	MPV196	NNP
cord-342419-liaihahj	75	2	[	[	-LRB-
cord-342419-liaihahj	75	3	54	54	CD
cord-342419-liaihahj	75	4	]	]	-RRB-
cord-342419-liaihahj	75	5	and	and	CC
cord-342419-liaihahj	75	6	DS7	ds7	VBP
cord-342419-liaihahj	75	7	[	[	-LRB-
cord-342419-liaihahj	75	8	49	49	CD
cord-342419-liaihahj	75	9	]	]	-RRB-
cord-342419-liaihahj	76	1	(	(	-LRB-
cord-342419-liaihahj	76	2	DS7	ds7	NN
cord-342419-liaihahj	76	3	epitope	epitope	NNP
cord-342419-liaihahj	76	4	)	)	-RRB-
cord-342419-liaihahj	76	5	,	,	,
cord-342419-liaihahj	76	6	and	and	CC
cord-342419-liaihahj	76	7	MPE8	MPE8	NNP
cord-342419-liaihahj	76	8	[	[	-LRB-
cord-342419-liaihahj	76	9	51	51	CD
cord-342419-liaihahj	76	10	]	]	-RRB-
cord-342419-liaihahj	77	1	and	and	CC
cord-342419-liaihahj	77	2	MPV364	MPV364	NNP
cord-342419-liaihahj	77	3	[	[	-LRB-
cord-342419-liaihahj	77	4	54	54	CD
cord-342419-liaihahj	77	5	]	]	-RRB-
cord-342419-liaihahj	77	6	(	(	-LRB-
cord-342419-liaihahj	77	7	site	site	NN
cord-342419-liaihahj	77	8	III	iii	CD
cord-342419-liaihahj	77	9	)	)	-RRB-
cord-342419-liaihahj	78	1	(	(	-LRB-
cord-342419-liaihahj	78	2	Fig	Fig	NNP
cord-342419-liaihahj	78	3	 	 	_SP
cord-342419-liaihahj	78	4	1A	1a	NN
cord-342419-liaihahj	78	5	;	;	:
cord-342419-liaihahj	78	6	S1	S1	NNP
cord-342419-liaihahj	78	7	Fig	Fig	NNP
cord-342419-liaihahj	78	8	)	)	-RRB-
cord-342419-liaihahj	78	9	.	.	.
cord-342419-liaihahj	79	1	These	these	DT
cord-342419-liaihahj	79	2	previously	previously	RB
cord-342419-liaihahj	79	3	discovered	discover	VBD
cord-342419-liaihahj	79	4	mAbs	mAbs	NNP
cord-342419-liaihahj	79	5	bind	bind	VB
cord-342419-liaihahj	79	6	both	both	DT
cord-342419-liaihahj	79	7	pre	pre	JJ
cord-342419-liaihahj	79	8	-	-	JJ
cord-342419-liaihahj	79	9	fusion	fusion	JJ
cord-342419-liaihahj	79	10	and	and	CC
cord-342419-liaihahj	79	11	post	post	JJ
cord-342419-liaihahj	79	12	-	-	JJ
cord-342419-liaihahj	79	13	fusion	fusion	JJ
cord-342419-liaihahj	79	14	conformations	conformation	NNS
cord-342419-liaihahj	79	15	of	of	IN
cord-342419-liaihahj	79	16	the	the	DT
cord-342419-liaihahj	79	17	hMPV	hmpv	NN
cord-342419-liaihahj	79	18	F	F	NNP
cord-342419-liaihahj	79	19	protein	protein	NN
cord-342419-liaihahj	79	20	with	with	IN
cord-342419-liaihahj	79	21	similar	similar	JJ
cord-342419-liaihahj	79	22	affinity	affinity	NN
cord-342419-liaihahj	79	23	,	,	,
cord-342419-liaihahj	79	24	except	except	IN
cord-342419-liaihahj	79	25	for	for	IN
cord-342419-liaihahj	79	26	MPE8	MPE8	NNP
cord-342419-liaihahj	79	27	,	,	,
cord-342419-liaihahj	79	28	which	which	WDT
cord-342419-liaihahj	79	29	has	have	VBZ
cord-342419-liaihahj	79	30	higher	high	JJR
cord-342419-liaihahj	79	31	affinity	affinity	NN
cord-342419-liaihahj	79	32	for	for	IN
cord-342419-liaihahj	79	33	the	the	DT
cord-342419-liaihahj	79	34	pre	pre	JJ
cord-342419-liaihahj	79	35	-	-	JJ
cord-342419-liaihahj	79	36	fusion	fusion	JJ
cord-342419-liaihahj	79	37	conformation	conformation	NN
cord-342419-liaihahj	79	38	of	of	IN
cord-342419-liaihahj	79	39	hMPV	hmpv	NN
cord-342419-liaihahj	79	40	F.	F.	NNP
cord-342419-liaihahj	79	41	Anti	Anti	NNP
cord-342419-liaihahj	79	42	-	-	JJ
cord-342419-liaihahj	79	43	penta	penta	NNP
cord-342419-liaihahj	79	44	-	-	HYPH
cord-342419-liaihahj	79	45	HIS	his	PRP$
cord-342419-liaihahj	79	46	biosensors	biosensor	NNS
cord-342419-liaihahj	79	47	were	be	VBD
cord-342419-liaihahj	79	48	loaded	load	VBN
cord-342419-liaihahj	79	49	with	with	IN
cord-342419-liaihahj	79	50	the	the	DT
cord-342419-liaihahj	79	51	hMPV	hmpv	NN
cord-342419-liaihahj	79	52	130-BV	130-bv	CD
cord-342419-liaihahj	79	53	F	F	NNP
cord-342419-liaihahj	79	54	[	[	-LRB-
cord-342419-liaihahj	79	55	38	38	CD
cord-342419-liaihahj	79	56	]	]	-RRB-
cord-342419-liaihahj	79	57	protein	protein	NN
cord-342419-liaihahj	79	58	(	(	-LRB-
cord-342419-liaihahj	79	59	A1	A1	NNP
cord-342419-liaihahj	79	60	subgroup	subgroup	NN
cord-342419-liaihahj	79	61	,	,	,
cord-342419-liaihahj	79	62	S1	S1	NNP
cord-342419-liaihahj	79	63	Table	Table	NNP
cord-342419-liaihahj	79	64	)	)	-RRB-
cord-342419-liaihahj	79	65	and	and	CC
cord-342419-liaihahj	79	66	then	then	RB
cord-342419-liaihahj	79	67	loaded	load	VBN
cord-342419-liaihahj	79	68	with	with	IN
cord-342419-liaihahj	79	69	one	one	CD
cord-342419-liaihahj	79	70	hMPV	hmpv	NN
cord-342419-liaihahj	79	71	Fspecific	Fspecific	NNP
cord-342419-liaihahj	79	72	mAb	mAb	NNP
cord-342419-liaihahj	79	73	,	,	,
cord-342419-liaihahj	79	74	followed	follow	VBN
cord-342419-liaihahj	79	75	by	by	IN
cord-342419-liaihahj	79	76	exposure	exposure	NN
cord-342419-liaihahj	79	77	to	to	IN
cord-342419-liaihahj	79	78	a	a	DT
cord-342419-liaihahj	79	79	second	second	JJ
cord-342419-liaihahj	79	80	mAb	mab	NN
cord-342419-liaihahj	79	81	.	.	.
cord-342419-liaihahj	79	82	mAbs	mabs	NN
cord-342419-liaihahj	79	83	MPV458	MPV458	NNP
cord-342419-liaihahj	79	84	and	and	CC
cord-342419-liaihahj	79	85	MPV465	MPV465	NNP
cord-342419-liaihahj	79	86	did	do	VBD
cord-342419-liaihahj	79	87	not	not	RB
cord-342419-liaihahj	79	88	compete	compete	VB
cord-342419-liaihahj	79	89	with	with	IN
cord-342419-liaihahj	79	90	any	any	DT
cord-342419-liaihahj	79	91	of	of	IN
cord-342419-liaihahj	79	92	the	the	DT
cord-342419-liaihahj	79	93	mapping	mapping	NN
cord-342419-liaihahj	79	94	control	control	NN
cord-342419-liaihahj	79	95	mAbs	mAbs	NNP
cord-342419-liaihahj	79	96	,	,	,
cord-342419-liaihahj	79	97	yet	yet	CC
cord-342419-liaihahj	79	98	competed	compete	VBD
cord-342419-liaihahj	79	99	for	for	IN
cord-342419-liaihahj	79	100	binding	bind	VBG
cord-342419-liaihahj	79	101	with	with	IN
cord-342419-liaihahj	79	102	each	each	DT
cord-342419-liaihahj	79	103	other	other	JJ
cord-342419-liaihahj	79	104	,	,	,
cord-342419-liaihahj	79	105	suggesting	suggest	VBG
cord-342419-liaihahj	79	106	these	these	DT
cord-342419-liaihahj	79	107	two	two	CD
cord-342419-liaihahj	79	108	mAbs	mAbs	NNP
cord-342419-liaihahj	79	109	bind	bind	NN
cord-342419-liaihahj	79	110	to	to	IN
cord-342419-liaihahj	79	111	a	a	DT
cord-342419-liaihahj	79	112	unique	unique	JJ
cord-342419-liaihahj	79	113	antigenic	antigenic	JJ
cord-342419-liaihahj	79	114	site	site	NN
cord-342419-liaihahj	79	115	on	on	IN
cord-342419-liaihahj	79	116	the	the	DT
cord-342419-liaihahj	79	117	hMPV	hmpv	NN
cord-342419-liaihahj	79	118	F	F	NNP
cord-342419-liaihahj	79	119	protein	protein	NN
cord-342419-liaihahj	79	120	.	.	.
cord-342419-liaihahj	80	1	Plaque	plaque	NN
cord-342419-liaihahj	80	2	neutralization	neutralization	NN
cord-342419-liaihahj	80	3	assays	assay	NNS
cord-342419-liaihahj	80	4	were	be	VBD
cord-342419-liaihahj	80	5	performed	perform	VBN
cord-342419-liaihahj	80	6	to	to	TO
cord-342419-liaihahj	80	7	determine	determine	VB
cord-342419-liaihahj	80	8	the	the	DT
cord-342419-liaihahj	80	9	neutralization	neutralization	NN
cord-342419-liaihahj	80	10	properties	property	NNS
cord-342419-liaihahj	80	11	of	of	IN
cord-342419-liaihahj	80	12	MPV458	MPV458	NNP
cord-342419-liaihahj	80	13	and	and	CC
cord-342419-liaihahj	80	14	MPV465	MPV465	NNP
cord-342419-liaihahj	80	15	against	against	IN
cord-342419-liaihahj	80	16	hMPV	hmpv	NN
cord-342419-liaihahj	80	17	subgroup	subgroup	NNP
cord-342419-liaihahj	80	18	B2	B2	NNP
cord-342419-liaihahj	80	19	(	(	-LRB-
cord-342419-liaihahj	81	1	strain	strain	VB
cord-342419-liaihahj	82	1	TN/93	TN/93	NNP
cord-342419-liaihahj	82	2	-	-	HYPH
cord-342419-liaihahj	82	3	32	32	CD
cord-342419-liaihahj	82	4	)	)	-RRB-
cord-342419-liaihahj	82	5	and	and	CC
cord-342419-liaihahj	83	1	hMPV	hMPV	NNP
cord-342419-liaihahj	83	2	subgroup	subgroup	NNP
cord-342419-liaihahj	83	3	A2	A2	NNP
cord-342419-liaihahj	83	4	(	(	-LRB-
cord-342419-liaihahj	83	5	strain	strain	NN
cord-342419-liaihahj	83	6	CAN/97	CAN/97	NNP
cord-342419-liaihahj	83	7	-	-	HYPH
cord-342419-liaihahj	83	8	83	83	CD
cord-342419-liaihahj	83	9	)	)	-RRB-
cord-342419-liaihahj	83	10	in	in	IN
cord-342419-liaihahj	83	11	vitro	vitro	FW
cord-342419-liaihahj	83	12	(	(	-LRB-
cord-342419-liaihahj	83	13	Fig	Fig	NNP
cord-342419-liaihahj	83	14	1B	1b	CD
cord-342419-liaihahj	83	15	)	)	-RRB-
cord-342419-liaihahj	83	16	.	.	.
cord-342419-liaihahj	84	1	MPV458	MPV458	NNP
cord-342419-liaihahj	84	2	neutralized	neutralize	VBD
cord-342419-liaihahj	84	3	hMPV	hmpv	NN
cord-342419-liaihahj	84	4	with	with	IN
cord-342419-liaihahj	84	5	50	50	CD
cord-342419-liaihahj	84	6	%	%	NN
cord-342419-liaihahj	84	7	inhibitory	inhibitory	JJ
cord-342419-liaihahj	84	8	concentration	concentration	NN
cord-342419-liaihahj	84	9	(	(	-LRB-
cord-342419-liaihahj	84	10	IC	IC	NNP
cord-342419-liaihahj	84	11	50	50	CD
cord-342419-liaihahj	84	12	)	)	-RRB-
cord-342419-liaihahj	84	13	values	value	NNS
cord-342419-liaihahj	84	14	of	of	IN
cord-342419-liaihahj	84	15	33	33	CD
cord-342419-liaihahj	84	16	ng	ng	NN
cord-342419-liaihahj	84	17	/	/	SYM
cord-342419-liaihahj	84	18	mL	ml	NN
cord-342419-liaihahj	84	19	for	for	IN
cord-342419-liaihahj	84	20	MPV	MPV	NNP
cord-342419-liaihahj	84	21	CAN/97	CAN/97	NNP
cord-342419-liaihahj	84	22	-	-	HYPH
cord-342419-liaihahj	84	23	83	83	CD
cord-342419-liaihahj	84	24	and	and	CC
cord-342419-liaihahj	84	25	490	490	CD
cord-342419-liaihahj	84	26	ng	ng	NN
cord-342419-liaihahj	84	27	/	/	SYM
cord-342419-liaihahj	84	28	mL	ml	NN
cord-342419-liaihahj	84	29	for	for	IN
cord-342419-liaihahj	84	30	MPV	MPV	NNP
cord-342419-liaihahj	84	31	TN/93	TN/93	NNP
cord-342419-liaihahj	84	32	-	-	HYPH
cord-342419-liaihahj	84	33	32	32	CD
cord-342419-liaihahj	84	34	,	,	,
cord-342419-liaihahj	84	35	while	while	IN
cord-342419-liaihahj	84	36	MPV465	MPV465	NNP
cord-342419-liaihahj	84	37	had	have	VBD
cord-342419-liaihahj	84	38	IC	IC	NNP
cord-342419-liaihahj	84	39	50	50	CD
cord-342419-liaihahj	84	40	values	value	NNS
cord-342419-liaihahj	84	41	of	of	IN
cord-342419-liaihahj	84	42	950	950	CD
cord-342419-liaihahj	84	43	and	and	CC
cord-342419-liaihahj	84	44	2700	2700	CD
cord-342419-liaihahj	84	45	ng	ng	NN
cord-342419-liaihahj	84	46	/	/	SYM
cord-342419-liaihahj	84	47	mL	ml	NN
cord-342419-liaihahj	84	48	,	,	,
cord-342419-liaihahj	84	49	respectively	respectively	RB
cord-342419-liaihahj	84	50	.	.	.
cord-342419-liaihahj	85	1	The	the	DT
cord-342419-liaihahj	85	2	neutralization	neutralization	NN
cord-342419-liaihahj	85	3	potency	potency	NN
cord-342419-liaihahj	85	4	of	of	IN
cord-342419-liaihahj	85	5	MPV458	MPV458	NNP
cord-342419-liaihahj	85	6	was	be	VBD
cord-342419-liaihahj	85	7	comparable	comparable	JJ
cord-342419-liaihahj	85	8	to	to	IN
cord-342419-liaihahj	85	9	mAbs	mAbs	NNP
cord-342419-liaihahj	85	10	MPE8	MPE8	NNP
cord-342419-liaihahj	86	1	and	and	CC
cord-342419-liaihahj	86	2	101F.	101f.	LS
cord-342419-liaihahj	86	3	We	-PRON-	PRP
cord-342419-liaihahj	86	4	next	next	RB
cord-342419-liaihahj	86	5	determined	determine	VBD
cord-342419-liaihahj	86	6	the	the	DT
cord-342419-liaihahj	86	7	binding	bind	VBG
cord-342419-liaihahj	86	8	properties	property	NNS
cord-342419-liaihahj	86	9	of	of	IN
cord-342419-liaihahj	86	10	MPV458	MPV458	NNP
cord-342419-liaihahj	86	11	and	and	CC
cord-342419-liaihahj	86	12	MPV465	MPV465	NNP
cord-342419-liaihahj	86	13	by	by	IN
cord-342419-liaihahj	86	14	ELISA	ELISA	NNP
cord-342419-liaihahj	86	15	and	and	CC
cord-342419-liaihahj	86	16	biolayer	biolayer	NN
cord-342419-liaihahj	86	17	interferometry	interferometry	NN
cord-342419-liaihahj	86	18	.	.	.
cord-342419-liaihahj	87	1	For	for	IN
cord-342419-liaihahj	87	2	ELISA	ELISA	NNP
cord-342419-liaihahj	87	3	,	,	,
cord-342419-liaihahj	87	4	the	the	DT
cord-342419-liaihahj	87	5	half	half	RB
cord-342419-liaihahj	87	6	-	-	HYPH
cord-342419-liaihahj	87	7	maximal	maximal	JJ
cord-342419-liaihahj	87	8	effective	effective	JJ
cord-342419-liaihahj	87	9	concentration	concentration	NN
cord-342419-liaihahj	87	10	(	(	-LRB-
cord-342419-liaihahj	87	11	EC	EC	NNP
cord-342419-liaihahj	87	12	50	50	CD
cord-342419-liaihahj	87	13	)	)	-RRB-
cord-342419-liaihahj	87	14	values	value	NNS
cord-342419-liaihahj	87	15	were	be	VBD
cord-342419-liaihahj	87	16	used	use	VBN
cord-342419-liaihahj	87	17	to	to	TO
cord-342419-liaihahj	87	18	quantify	quantify	VB
cord-342419-liaihahj	87	19	binding	bind	VBG
cord-342419-liaihahj	87	20	between	between	IN
cord-342419-liaihahj	87	21	mAbs	mAbs	NNP
cord-342419-liaihahj	87	22	across	across	IN
cord-342419-liaihahj	87	23	multiple	multiple	JJ
cord-342419-liaihahj	87	24	hMPV	hmpv	NN
cord-342419-liaihahj	87	25	F	F	NNP
cord-342419-liaihahj	87	26	protein	protein	NN
cord-342419-liaihahj	87	27	constructs	construct	NNS
cord-342419-liaihahj	87	28	(	(	-LRB-
cord-342419-liaihahj	87	29	Fig	Fig	NNP
cord-342419-liaihahj	87	30	2A	2a	CD
cord-342419-liaihahj	87	31	;	;	:
cord-342419-liaihahj	87	32	S2	S2	NNP
cord-342419-liaihahj	87	33	Fig	Fig	NNP
cord-342419-liaihahj	87	34	;	;	:
cord-342419-liaihahj	87	35	S3	S3	NNP
cord-342419-liaihahj	87	36	Fig	Fig	NNP
cord-342419-liaihahj	87	37	;	;	:
cord-342419-liaihahj	87	38	S1	S1	NNP
cord-342419-liaihahj	87	39	Table	Table	NNP
cord-342419-liaihahj	87	40	)	)	-RRB-
cord-342419-liaihahj	87	41	.	.	.
cord-342419-liaihahj	88	1	Generating	generate	VBG
cord-342419-liaihahj	88	2	trimeric	trimeric	DT
cord-342419-liaihahj	88	3	hMPV	hmpv	NN
cord-342419-liaihahj	88	4	F	F	NNP
cord-342419-liaihahj	88	5	can	can	MD
cord-342419-liaihahj	88	6	be	be	VB
cord-342419-liaihahj	88	7	achieved	achieve	VBN
cord-342419-liaihahj	88	8	by	by	IN
cord-342419-liaihahj	88	9	treating	treat	VBG
cord-342419-liaihahj	88	10	purified	purify	VBN
cord-342419-liaihahj	88	11	protein	protein	NN
cord-342419-liaihahj	88	12	with	with	IN
cord-342419-liaihahj	88	13	trypsin	trypsin	NN
cord-342419-liaihahj	88	14	as	as	IN
cord-342419-liaihahj	88	15	previously	previously	RB
cord-342419-liaihahj	88	16	described	describe	VBD
cord-342419-liaihahj	88	17	[	[	-LRB-
cord-342419-liaihahj	88	18	43	43	CD
cord-342419-liaihahj	88	19	,	,	,
cord-342419-liaihahj	88	20	54	54	CD
cord-342419-liaihahj	88	21	]	]	-RRB-
cord-342419-liaihahj	88	22	,	,	,
cord-342419-liaihahj	88	23	although	although	IN
cord-342419-liaihahj	88	24	this	this	DT
cord-342419-liaihahj	88	25	process	process	NN
cord-342419-liaihahj	88	26	generates	generate	VBZ
cord-342419-liaihahj	88	27	batch	batch	NN
cord-342419-liaihahj	88	28	to	to	TO
cord-342419-liaihahj	88	29	batch	batch	VB
cord-342419-liaihahj	88	30	variation	variation	NN
cord-342419-liaihahj	88	31	of	of	IN
cord-342419-liaihahj	88	32	both	both	DT
cord-342419-liaihahj	88	33	pre	pre	JJ
cord-342419-liaihahj	88	34	-	-	JJ
cord-342419-liaihahj	88	35	fusion	fusion	JJ
cord-342419-liaihahj	88	36	and	and	CC
cord-342419-liaihahj	88	37	post	post	JJ
cord-342419-liaihahj	88	38	-	-	JJ
cord-342419-liaihahj	88	39	fusion	fusion	JJ
cord-342419-liaihahj	88	40	conformations	conformation	NNS
cord-342419-liaihahj	88	41	[	[	-LRB-
cord-342419-liaihahj	88	42	54	54	CD
cord-342419-liaihahj	88	43	]	]	-RRB-
cord-342419-liaihahj	88	44	.	.	.
cord-342419-liaihahj	89	1	MPV458	MPV458	NNP
cord-342419-liaihahj	89	2	binds	bind	VBZ
cord-342419-liaihahj	89	3	to	to	IN
cord-342419-liaihahj	89	4	hMPV	hmpv	VB
cord-342419-liaihahj	89	5	F	F	NNP
cord-342419-liaihahj	89	6	proteins	protein	NNS
cord-342419-liaihahj	89	7	from	from	IN
cord-342419-liaihahj	89	8	all	all	DT
cord-342419-liaihahj	89	9	four	four	CD
cord-342419-liaihahj	89	10	hMPV	hmpv	NN
cord-342419-liaihahj	89	11	F	f	NN
cord-342419-liaihahj	89	12	subgroups	subgroup	NNS
cord-342419-liaihahj	89	13	,	,	,
cord-342419-liaihahj	89	14	while	while	IN
cord-342419-liaihahj	89	15	MPV465	MPV465	NNP
cord-342419-liaihahj	89	16	showed	show	VBD
cord-342419-liaihahj	89	17	binding	bind	VBG
cord-342419-liaihahj	89	18	to	to	IN
cord-342419-liaihahj	89	19	hMPV	hmpv	VB
cord-342419-liaihahj	89	20	F	F	NNP
cord-342419-liaihahj	89	21	proteins	protein	NNS
cord-342419-liaihahj	89	22	from	from	IN
cord-342419-liaihahj	89	23	subgroups	subgroup	NNS
cord-342419-liaihahj	89	24	A2	A2	NNP
cord-342419-liaihahj	89	25	,	,	,
cord-342419-liaihahj	89	26	B1	b1	NN
cord-342419-liaihahj	89	27	,	,	,
cord-342419-liaihahj	89	28	and	and	CC
cord-342419-liaihahj	89	29	B2	b2	NN
cord-342419-liaihahj	89	30	(	(	-LRB-
cord-342419-liaihahj	89	31	Fig	Fig	NNP
cord-342419-liaihahj	89	32	2A	2a	CD
cord-342419-liaihahj	89	33	)	)	-RRB-
cord-342419-liaihahj	89	34	.	.	.
cord-342419-liaihahj	90	1	We	-PRON-	PRP
cord-342419-liaihahj	90	2	next	next	RB
cord-342419-liaihahj	90	3	assessed	assess	VBD
cord-342419-liaihahj	90	4	binding	bind	VBG
cord-342419-liaihahj	90	5	to	to	IN
cord-342419-liaihahj	90	6	exclusively	exclusively	RB
cord-342419-liaihahj	90	7	monomeric	monomeric	JJ
cord-342419-liaihahj	90	8	(	(	-LRB-
cord-342419-liaihahj	90	9	presumed	presume	VBN
cord-342419-liaihahj	90	10	pre	pre	JJ
cord-342419-liaihahj	90	11	-	-	JJ
cord-342419-liaihahj	90	12	fusion	fusion	JJ
cord-342419-liaihahj	90	13	)	)	-RRB-
cord-342419-liaihahj	90	14	and	and	CC
cord-342419-liaihahj	90	15	trimeric	trimeric	NNP
cord-342419-liaihahj	90	16	(	(	-LRB-
cord-342419-liaihahj	90	17	post	post	JJ
cord-342419-liaihahj	90	18	-	-	JJ
cord-342419-liaihahj	90	19	fusion	fusion	JJ
cord-342419-liaihahj	90	20	)	)	-RRB-
cord-342419-liaihahj	90	21	hMPV	hmpv	NN
cord-342419-liaihahj	90	22	B2	b2	NN
cord-342419-liaihahj	90	23	F	F	NNP
cord-342419-liaihahj	90	24	proteins	protein	NNS
cord-342419-liaihahj	90	25	that	that	WDT
cord-342419-liaihahj	90	26	were	be	VBD
cord-342419-liaihahj	90	27	treated	treat	VBN
cord-342419-liaihahj	90	28	with	with	IN
cord-342419-liaihahj	90	29	trypsin	trypsin	NN
cord-342419-liaihahj	90	30	to	to	TO
cord-342419-liaihahj	90	31	induce	induce	VB
cord-342419-liaihahj	90	32	cleavage	cleavage	NN
cord-342419-liaihahj	90	33	(	(	-LRB-
cord-342419-liaihahj	90	34	Fig	fig	NN
cord-342419-liaihahj	90	35	2A	2a	NN
cord-342419-liaihahj	90	36	;	;	:
cord-342419-liaihahj	90	37	S3	S3	NNP
cord-342419-liaihahj	90	38	Fig	Fig	NNP
cord-342419-liaihahj	90	39	)	)	-RRB-
cord-342419-liaihahj	90	40	,	,	,
cord-342419-liaihahj	90	41	and	and	CC
cord-342419-liaihahj	90	42	MPV458	MPV458	NNP
cord-342419-liaihahj	90	43	and	and	CC
cord-342419-liaihahj	90	44	MPV465	MPV465	NNP
cord-342419-liaihahj	90	45	had	have	VBD
cord-342419-liaihahj	90	46	higher	high	JJR
cord-342419-liaihahj	90	47	binding	binding	NN
cord-342419-liaihahj	90	48	to	to	IN
cord-342419-liaihahj	90	49	monomeric	monomeric	JJ
cord-342419-liaihahj	90	50	hMPV	hmpv	NN
cord-342419-liaihahj	90	51	F	f	NN
cord-342419-liaihahj	91	1	than	than	IN
cord-342419-liaihahj	91	2	to	to	IN
cord-342419-liaihahj	91	3	trimeric	trimeric	NNP
cord-342419-liaihahj	91	4	hMPV	hmpv	NN
cord-342419-liaihahj	91	5	F.	F.	NNP
cord-342419-liaihahj	91	6	MPV458	MPV458	NNP
cord-342419-liaihahj	91	7	had	have	VBD
cord-342419-liaihahj	91	8	a	a	DT
cord-342419-liaihahj	91	9	nearly	nearly	RB
cord-342419-liaihahj	91	10	five	five	CD
cord-342419-liaihahj	91	11	-	-	RB
cord-342419-liaihahj	91	12	fold	fold	RB
cord-342419-liaihahj	91	13	lower	low	JJR
cord-342419-liaihahj	91	14	EC	EC	NNP
cord-342419-liaihahj	91	15	50	50	CD
cord-342419-liaihahj	91	16	to	to	IN
cord-342419-liaihahj	91	17	monomeric	monomeric	JJ
cord-342419-liaihahj	91	18	hMPV	hmpv	NN
cord-342419-liaihahj	91	19	B2	b2	NN
cord-342419-liaihahj	91	20	F	F	NNP
cord-342419-liaihahj	91	21	than	than	IN
cord-342419-liaihahj	91	22	to	to	IN
cord-342419-liaihahj	91	23	trimeric	trimeric	NNP
cord-342419-liaihahj	92	1	hMPV	hMPV	NNP
cord-342419-liaihahj	92	2	B2	B2	NNP
cord-342419-liaihahj	92	3	F.	F.	NNP
cord-342419-liaihahj	92	4	MPV465	MPV465	NNP
cord-342419-liaihahj	92	5	bound	bind	VBN
cord-342419-liaihahj	92	6	well	well	RB
cord-342419-liaihahj	92	7	to	to	IN
cord-342419-liaihahj	92	8	the	the	DT
cord-342419-liaihahj	92	9	hMPV	hmpv	NN
cord-342419-liaihahj	92	10	B2	b2	NN
cord-342419-liaihahj	92	11	F	F	NNP
cord-342419-liaihahj	92	12	monomer	monomer	NN
cord-342419-liaihahj	92	13	,	,	,
cord-342419-liaihahj	92	14	while	while	IN
cord-342419-liaihahj	92	15	binding	bind	VBG
cord-342419-liaihahj	92	16	was	be	VBD
cord-342419-liaihahj	92	17	completely	completely	RB
cord-342419-liaihahj	92	18	abrogated	abrogate	VBN
cord-342419-liaihahj	92	19	binding	bind	VBG
cord-342419-liaihahj	92	20	to	to	IN
cord-342419-liaihahj	92	21	the	the	DT
cord-342419-liaihahj	92	22	post	post	JJ
cord-342419-liaihahj	92	23	-	-	JJ
cord-342419-liaihahj	92	24	fusion	fusion	JJ
cord-342419-liaihahj	92	25	hMPV	hmpv	NN
cord-342419-liaihahj	92	26	B2	b2	NN
cord-342419-liaihahj	92	27	F	F	NNP
cord-342419-liaihahj	92	28	trimer	trimer	NN
cord-342419-liaihahj	92	29	.	.	.
cord-342419-liaihahj	93	1	These	these	DT
cord-342419-liaihahj	93	2	data	datum	NNS
cord-342419-liaihahj	93	3	indicate	indicate	VBP
cord-342419-liaihahj	93	4	the	the	DT
cord-342419-liaihahj	93	5	epitope	epitope	NN
cord-342419-liaihahj	93	6	for	for	IN
cord-342419-liaihahj	93	7	MPV458	MPV458	NNP
cord-342419-liaihahj	93	8	and	and	CC
cord-342419-liaihahj	93	9	MPV465	MPV465	NNP
cord-342419-liaihahj	93	10	is	be	VBZ
cord-342419-liaihahj	93	11	predominantly	predominantly	RB
cord-342419-liaihahj	93	12	exposed	expose	VBN
cord-342419-liaihahj	93	13	on	on	IN
cord-342419-liaihahj	93	14	pre	pre	JJ
cord-342419-liaihahj	93	15	-	-	NN
cord-342419-liaihahj	93	16	fusion	fusion	NN
cord-342419-liaihahj	93	17	and/or	and/or	CC
cord-342419-liaihahj	93	18	monomeric	monomeric	JJ
cord-342419-liaihahj	93	19	hMPV	hmpv	NN
cord-342419-liaihahj	94	1	F.	F.	NNP
cord-342419-liaihahj	94	2	Binding	Binding	NNP
cord-342419-liaihahj	94	3	affinity	affinity	NN
cord-342419-liaihahj	94	4	of	of	IN
cord-342419-liaihahj	94	5	the	the	DT
cord-342419-liaihahj	94	6	mAbs	mabs	NN
cord-342419-liaihahj	94	7	was	be	VBD
cord-342419-liaihahj	94	8	assessed	assess	VBN
cord-342419-liaihahj	94	9	by	by	IN
cord-342419-liaihahj	94	10	biolayer	biolayer	NN
cord-342419-liaihahj	94	11	interferometry	interferometry	NN
cord-342419-liaihahj	94	12	using	use	VBG
cord-342419-liaihahj	94	13	monomeric	monomeric	JJ
cord-342419-liaihahj	94	14	hMPV	hmpv	NN
cord-342419-liaihahj	94	15	B2	b2	NN
cord-342419-liaihahj	94	16	F	F	NNP
cord-342419-liaihahj	94	17	protein	protein	NN
cord-342419-liaihahj	94	18	(	(	-LRB-
cord-342419-liaihahj	94	19	Fig	Fig	NNP
cord-342419-liaihahj	94	20	2B	2b	CD
cord-342419-liaihahj	94	21	)	)	-RRB-
cord-342419-liaihahj	94	22	.	.	.
cord-342419-liaihahj	95	1	Affinity	affinity	NN
cord-342419-liaihahj	95	2	measurements	measurement	NNS
cord-342419-liaihahj	95	3	were	be	VBD
cord-342419-liaihahj	95	4	completed	complete	VBN
cord-342419-liaihahj	95	5	by	by	IN
cord-342419-liaihahj	95	6	cleaving	cleave	VBG
cord-342419-liaihahj	95	7	mAbs	mAbs	NNP
cord-342419-liaihahj	95	8	to	to	IN
cord-342419-liaihahj	95	9	Fab	fab	JJ
cord-342419-liaihahj	95	10	fragments	fragment	NNS
cord-342419-liaihahj	95	11	and	and	CC
cord-342419-liaihahj	95	12	coupling	couple	VBG
cord-342419-liaihahj	95	13	biotinylated	biotinylated	JJ
cord-342419-liaihahj	95	14	hMPV	hmpv	NN
cord-342419-liaihahj	95	15	B2	B2	NNP
cord-342419-liaihahj	95	16	F	F	NNP
cord-342419-liaihahj	95	17	monomer	monomer	NN
cord-342419-liaihahj	95	18	to	to	IN
cord-342419-liaihahj	95	19	streptavidin	streptavidin	NNP
cord-342419-liaihahj	95	20	biosensors	biosensor	NNS
cord-342419-liaihahj	95	21	.	.	.
cord-342419-liaihahj	96	1	Association	Association	NNP
cord-342419-liaihahj	96	2	(	(	-LRB-
cord-342419-liaihahj	96	3	K	K	NNP
cord-342419-liaihahj	96	4	ON	ON	NNP
cord-342419-liaihahj	96	5	)	)	-RRB-
cord-342419-liaihahj	96	6	,	,	,
cord-342419-liaihahj	96	7	dissociation	dissociation	NN
cord-342419-liaihahj	96	8	(	(	-LRB-
cord-342419-liaihahj	96	9	K	K	NNP
cord-342419-liaihahj	96	10	OFF	OFF	NNP
cord-342419-liaihahj	96	11	)	)	-RRB-
cord-342419-liaihahj	96	12	,	,	,
cord-342419-liaihahj	96	13	and	and	CC
cord-342419-liaihahj	96	14	K	k	NN
cord-342419-liaihahj	96	15	D	d	NN
cord-342419-liaihahj	96	16	values	value	NNS
cord-342419-liaihahj	96	17	were	be	VBD
cord-342419-liaihahj	96	18	comparable	comparable	JJ
cord-342419-liaihahj	96	19	for	for	IN
cord-342419-liaihahj	96	20	MPV458	MPV458	NNP
cord-342419-liaihahj	96	21	and	and	CC
cord-342419-liaihahj	96	22	MPV465	MPV465	NNP
cord-342419-liaihahj	96	23	Fabs	Fabs	NNPS
cord-342419-liaihahj	96	24	,	,	,
cord-342419-liaihahj	96	25	and	and	CC
cord-342419-liaihahj	96	26	the	the	DT
cord-342419-liaihahj	96	27	Fabs	Fabs	NNPS
cord-342419-liaihahj	96	28	had	have	VBD
cord-342419-liaihahj	96	29	a	a	DT
cord-342419-liaihahj	96	30	2	2	CD
cord-342419-liaihahj	96	31	-	-	SYM
cord-342419-liaihahj	96	32	3	3	CD
cord-342419-liaihahj	96	33	log	log	NN
cord-342419-liaihahj	96	34	higher	high	JJR
cord-342419-liaihahj	96	35	K	k	NN
cord-342419-liaihahj	96	36	D	D	NNP
cord-342419-liaihahj	96	37	than	than	IN
cord-342419-liaihahj	96	38	the	the	DT
cord-342419-liaihahj	96	39	control	control	NN
cord-342419-liaihahj	96	40	mAb	mab	NN
cord-342419-liaihahj	96	41	101F.	101f.	CD
cord-342419-liaihahj	96	42	Binding	bind	VBG
cord-342419-liaihahj	96	43	K	k	NN
cord-342419-liaihahj	96	44	D	d	NN
cord-342419-liaihahj	96	45	values	value	NNS
cord-342419-liaihahj	96	46	were	be	VBD
cord-342419-liaihahj	96	47	0.85	0.85	CD
cord-342419-liaihahj	96	48	nM	nm	NN
cord-342419-liaihahj	96	49	,	,	,
cord-342419-liaihahj	96	50	0.075	0.075	CD
cord-342419-liaihahj	96	51	nM	nm	NN
cord-342419-liaihahj	96	52	,	,	,
cord-342419-liaihahj	96	53	and	and	CC
cord-342419-liaihahj	96	54	430	430	CD
cord-342419-liaihahj	96	55	nM	nm	NN
cord-342419-liaihahj	96	56	for	for	IN
cord-342419-liaihahj	96	57	Fabs	Fabs	NNPS
cord-342419-liaihahj	96	58	of	of	IN
cord-342419-liaihahj	96	59	MPV458	MPV458	NNP
cord-342419-liaihahj	96	60	,	,	,
cord-342419-liaihahj	96	61	MPV465	MPV465	NNP
cord-342419-liaihahj	96	62	,	,	,
cord-342419-liaihahj	96	63	and	and	CC
cord-342419-liaihahj	96	64	101F	101f	CD
cord-342419-liaihahj	96	65	to	to	IN
cord-342419-liaihahj	96	66	monomeric	monomeric	JJ
cord-342419-liaihahj	96	67	hMPV	hmpv	NN
cord-342419-liaihahj	96	68	B2	b2	NN
cord-342419-liaihahj	96	69	F	F	NNP
cord-342419-liaihahj	96	70	protein	protein	NN
cord-342419-liaihahj	96	71	,	,	,
cord-342419-liaihahj	96	72	respectively	respectively	RB
cord-342419-liaihahj	96	73	.	.	.
cord-342419-liaihahj	97	1	To	to	TO
cord-342419-liaihahj	97	2	fully	fully	RB
cord-342419-liaihahj	97	3	define	define	VB
cord-342419-liaihahj	97	4	the	the	DT
cord-342419-liaihahj	97	5	epitope	epitope	NN
cord-342419-liaihahj	97	6	targeted	target	VBN
cord-342419-liaihahj	97	7	by	by	IN
cord-342419-liaihahj	97	8	the	the	DT
cord-342419-liaihahj	97	9	newly	newly	RB
cord-342419-liaihahj	97	10	isolated	isolate	VBN
cord-342419-liaihahj	97	11	mAbs	mAbs	NNP
cord-342419-liaihahj	97	12	,	,	,
cord-342419-liaihahj	97	13	we	-PRON-	PRP
cord-342419-liaihahj	97	14	co	co	VBD
cord-342419-liaihahj	97	15	-	-	VBD
cord-342419-liaihahj	97	16	crystallized	crystallize	VBN
cord-342419-liaihahj	98	1	the	the	DT
cord-342419-liaihahj	98	2	Fab	Fab	NNP
cord-342419-liaihahj	98	3	of	of	IN
cord-342419-liaihahj	98	4	MPV458	MPV458	NNP
cord-342419-liaihahj	98	5	in	in	IN
cord-342419-liaihahj	98	6	complex	complex	NN
cord-342419-liaihahj	98	7	with	with	IN
cord-342419-liaihahj	98	8	hMPV	hmpv	NN
cord-342419-liaihahj	98	9	B2	b2	NN
cord-342419-liaihahj	98	10	F.	F.	NNP
cord-342419-liaihahj	98	11	Trypsinization	Trypsinization	NNP
cord-342419-liaihahj	98	12	of	of	IN
cord-342419-liaihahj	99	1	hMPV	hMPV	NNP
cord-342419-liaihahj	99	2	B2	B2	NNP
cord-342419-liaihahj	99	3	F	F	NNP
cord-342419-liaihahj	99	4	generated	generate	VBD
cord-342419-liaihahj	99	5	trimeric	trimeric	JJ
cord-342419-liaihahj	99	6	and	and	CC
cord-342419-liaihahj	99	7	monomeric	monomeric	JJ
cord-342419-liaihahj	99	8	versions	version	NNS
cord-342419-liaihahj	99	9	of	of	IN
cord-342419-liaihahj	99	10	hMPV	hmpv	NN
cord-342419-liaihahj	99	11	F	F	NNP
cord-342419-liaihahj	99	12	as	as	IN
cord-342419-liaihahj	99	13	assessed	assess	VBN
cord-342419-liaihahj	99	14	by	by	IN
cord-342419-liaihahj	99	15	size	size	NN
cord-342419-liaihahj	99	16	exclusion	exclusion	NN
cord-342419-liaihahj	99	17	chromatography	chromatography	NN
cord-342419-liaihahj	99	18	(	(	-LRB-
cord-342419-liaihahj	99	19	S4	S4	NNP
cord-342419-liaihahj	99	20	Fig	Fig	NNP
cord-342419-liaihahj	99	21	)	)	-RRB-
cord-342419-liaihahj	99	22	.	.	.
cord-342419-liaihahj	100	1	Cleavage	cleavage	NN
cord-342419-liaihahj	100	2	of	of	IN
cord-342419-liaihahj	100	3	MPV458	MPV458	NNP
cord-342419-liaihahj	100	4	and	and	CC
cord-342419-liaihahj	100	5	MPV465	MPV465	NNP
cord-342419-liaihahj	100	6	mAbs	mAbs	NNP
cord-342419-liaihahj	100	7	to	to	IN
cord-342419-liaihahj	100	8	Fab	fab	JJ
cord-342419-liaihahj	100	9	fragments	fragment	NNS
cord-342419-liaihahj	100	10	and	and	CC
cord-342419-liaihahj	100	11	subsequent	subsequent	JJ
cord-342419-liaihahj	100	12	addition	addition	NN
cord-342419-liaihahj	100	13	of	of	IN
cord-342419-liaihahj	100	14	these	these	DT
cord-342419-liaihahj	100	15	Fabs	Fabs	NNPS
cord-342419-liaihahj	100	16	to	to	IN
cord-342419-liaihahj	100	17	trypsinized	trypsinize	VBN
cord-342419-liaihahj	100	18	trimeric	trimeric	DT
cord-342419-liaihahj	101	1	hMPV	hMPV	NNP
cord-342419-liaihahj	101	2	B2	B2	NNP
cord-342419-liaihahj	101	3	F	F	NNP
cord-342419-liaihahj	101	4	resulted	result	VBD
cord-342419-liaihahj	101	5	in	in	IN
cord-342419-liaihahj	101	6	monomeric	monomeric	JJ
cord-342419-liaihahj	101	7	hMPV	hmpv	NN
cord-342419-liaihahj	101	8	F	F	NNP
cord-342419-liaihahj	101	9	-	-	HYPH
cord-342419-liaihahj	101	10	Fab	Fab	NNP
cord-342419-liaihahj	101	11	complexes	complex	NNS
cord-342419-liaihahj	101	12	(	(	-LRB-
cord-342419-liaihahj	101	13	S4	S4	NNP
cord-342419-liaihahj	101	14	Fig	Fig	NNP
cord-342419-liaihahj	101	15	;	;	:
cord-342419-liaihahj	101	16	S5	S5	NNP
cord-342419-liaihahj	101	17	 	 	_SP
cord-342419-liaihahj	101	18	Fig	Fig	NNP
cord-342419-liaihahj	101	19	)	)	-RRB-
cord-342419-liaihahj	101	20	.	.	.
cord-342419-liaihahj	102	1	Although	although	IN
cord-342419-liaihahj	102	2	the	the	DT
cord-342419-liaihahj	102	3	hMPV	hmpv	NN
cord-342419-liaihahj	102	4	B2	b2	NN
cord-342419-liaihahj	102	5	F	F	NNP
cord-342419-liaihahj	102	6	trimer	trimer	NN
cord-342419-liaihahj	102	7	appeared	appear	VBD
cord-342419-liaihahj	102	8	to	to	TO
cord-342419-liaihahj	102	9	fall	fall	VB
cord-342419-liaihahj	102	10	apart	apart	RB
cord-342419-liaihahj	102	11	upon	upon	IN
cord-342419-liaihahj	102	12	Fab	fab	JJ
cord-342419-liaihahj	102	13	binding	binding	NN
cord-342419-liaihahj	102	14	,	,	,
cord-342419-liaihahj	102	15	we	-PRON-	PRP
cord-342419-liaihahj	102	16	can	can	MD
cord-342419-liaihahj	102	17	not	not	RB
cord-342419-liaihahj	102	18	attribute	attribute	VB
cord-342419-liaihahj	102	19	this	this	DT
cord-342419-liaihahj	102	20	to	to	IN
cord-342419-liaihahj	102	21	binding	bind	VBG
cord-342419-liaihahj	102	22	of	of	IN
cord-342419-liaihahj	102	23	MPV458	MPV458	NNP
cord-342419-liaihahj	102	24	and	and	CC
cord-342419-liaihahj	102	25	MPV465	MPV465	NNP
cord-342419-liaihahj	102	26	as	as	IN
cord-342419-liaihahj	102	27	other	other	JJ
cord-342419-liaihahj	102	28	Fabs	Fabs	NNPS
cord-342419-liaihahj	102	29	also	also	RB
cord-342419-liaihahj	102	30	caused	cause	VBD
cord-342419-liaihahj	102	31	trimer	trimer	NN
cord-342419-liaihahj	102	32	dissociation	dissociation	NN
cord-342419-liaihahj	102	33	of	of	IN
cord-342419-liaihahj	102	34	this	this	DT
cord-342419-liaihahj	102	35	construct	construct	NN
cord-342419-liaihahj	102	36	.	.	.
cord-342419-liaihahj	103	1	The	the	DT
cord-342419-liaihahj	103	2	MPV458-hMPV	mpv458-hmpv	NN
cord-342419-liaihahj	103	3	B2	b2	NN
cord-342419-liaihahj	103	4	F	F	NNP
cord-342419-liaihahj	103	5	complex	complex	NN
cord-342419-liaihahj	103	6	was	be	VBD
cord-342419-liaihahj	103	7	subjected	subject	VBN
cord-342419-liaihahj	103	8	to	to	IN
cord-342419-liaihahj	103	9	crystallization	crystallization	NN
cord-342419-liaihahj	103	10	screening	screen	VBG
cord-342419-liaihahj	103	11	 	 	_SP
cord-342419-liaihahj	103	12	Antibody	Antibody	NNP
cord-342419-liaihahj	103	13	recognition	recognition	NN
cord-342419-liaihahj	103	14	of	of	IN
cord-342419-liaihahj	103	15	the	the	DT
cord-342419-liaihahj	103	16	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	103	17	fusion	fusion	NN
cord-342419-liaihahj	103	18	protein	protein	NN
cord-342419-liaihahj	103	19	trimer	trimer	NN
cord-342419-liaihahj	103	20	interface	interface	NN
cord-342419-liaihahj	103	21	and	and	CC
cord-342419-liaihahj	103	22	crystals	crystal	NNS
cord-342419-liaihahj	103	23	were	be	VBD
cord-342419-liaihahj	103	24	obtained	obtain	VBN
cord-342419-liaihahj	103	25	in	in	IN
cord-342419-liaihahj	103	26	0.5	0.5	CD
cord-342419-liaihahj	103	27	M	m	CD
cord-342419-liaihahj	103	28	ammonium	ammonium	NN
cord-342419-liaihahj	103	29	sulfate	sulfate	NN
cord-342419-liaihahj	103	30	,	,	,
cord-342419-liaihahj	103	31	0.1	0.1	CD
cord-342419-liaihahj	103	32	M	m	NN
cord-342419-liaihahj	103	33	sodium	sodium	NN
cord-342419-liaihahj	103	34	citrate	citrate	NNP
cord-342419-liaihahj	103	35	tribasic	tribasic	NNP
cord-342419-liaihahj	103	36	dihydrate	dihydrate	NNP
cord-342419-liaihahj	103	37	pH	pH	NNP
cord-342419-liaihahj	103	38	5.6	5.6	CD
cord-342419-liaihahj	103	39	,	,	,
cord-342419-liaihahj	103	40	and	and	CC
cord-342419-liaihahj	103	41	1.0	1.0	CD
cord-342419-liaihahj	103	42	M	M	NNP
cord-342419-liaihahj	103	43	Lithium	Lithium	NNP
cord-342419-liaihahj	103	44	sulfate	sulfate	NN
cord-342419-liaihahj	103	45	monohydrate	monohydrate	NN
cord-342419-liaihahj	103	46	.	.	.
cord-342419-liaihahj	104	1	Crystals	crystal	NNS
cord-342419-liaihahj	104	2	were	be	VBD
cord-342419-liaihahj	104	3	harvested	harvest	VBN
cord-342419-liaihahj	104	4	and	and	CC
cord-342419-liaihahj	104	5	X	x	NN
cord-342419-liaihahj	104	6	-	-	NN
cord-342419-liaihahj	104	7	ray	ray	NN
cord-342419-liaihahj	104	8	diffraction	diffraction	NN
cord-342419-liaihahj	104	9	data	datum	NNS
cord-342419-liaihahj	104	10	was	be	VBD
cord-342419-liaihahj	104	11	collected	collect	VBN
cord-342419-liaihahj	104	12	,	,	,
cord-342419-liaihahj	104	13	and	and	CC
cord-342419-liaihahj	104	14	the	the	DT
cord-342419-liaihahj	104	15	structure	structure	NN
cord-342419-liaihahj	104	16	of	of	IN
cord-342419-liaihahj	104	17	the	the	DT
cord-342419-liaihahj	104	18	complex	complex	NN
cord-342419-liaihahj	104	19	was	be	VBD
cord-342419-liaihahj	104	20	determined	determine	VBN
cord-342419-liaihahj	104	21	to	to	IN
cord-342419-liaihahj	104	22	3.1	3.1	CD
cord-342419-liaihahj	104	23	Å	å	NN
cord-342419-liaihahj	104	24	(	(	-LRB-
cord-342419-liaihahj	104	25	Fig	Fig	NNP
cord-342419-liaihahj	104	26	3	3	CD
cord-342419-liaihahj	104	27	;	;	:
cord-342419-liaihahj	104	28	S3	S3	NNP
cord-342419-liaihahj	104	29	Table	Table	NNP
cord-342419-liaihahj	104	30	)	)	-RRB-
cord-342419-liaihahj	104	31	.	.	.
cord-342419-liaihahj	105	1	The	the	DT
cord-342419-liaihahj	105	2	asymmetric	asymmetric	JJ
cord-342419-liaihahj	105	3	unit	unit	NN
cord-342419-liaihahj	105	4	contained	contain	VBD
cord-342419-liaihahj	105	5	one	one	CD
cord-342419-liaihahj	105	6	hMPV	hmpv	NN
cord-342419-liaihahj	105	7	F	F	NNP
cord-342419-liaihahj	105	8	protomer	protomer	NNP
cord-342419-liaihahj	105	9	with	with	IN
cord-342419-liaihahj	105	10	one	one	CD
cord-342419-liaihahj	105	11	MPV458-Fab	MPV458-Fab	NNP
cord-342419-liaihahj	105	12	molecule	molecule	NN
cord-342419-liaihahj	105	13	.	.	.
cord-342419-liaihahj	106	1	hMPV	hMPV	NNP
cord-342419-liaihahj	106	2	F	F	NNP
cord-342419-liaihahj	106	3	was	be	VBD
cord-342419-liaihahj	106	4	observed	observe	VBN
cord-342419-liaihahj	106	5	in	in	IN
cord-342419-liaihahj	106	6	the	the	DT
cord-342419-liaihahj	106	7	pre	pre	JJ
cord-342419-liaihahj	106	8	-	-	JJ
cord-342419-liaihahj	106	9	fusion	fusion	JJ
cord-342419-liaihahj	106	10	conformation	conformation	NN
cord-342419-liaihahj	106	11	,	,	,
cord-342419-liaihahj	106	12	although	although	IN
cord-342419-liaihahj	106	13	no	no	DT
cord-342419-liaihahj	106	14	trimeric	trimeric	JJ
cord-342419-liaihahj	106	15	structure	structure	NN
cord-342419-liaihahj	106	16	was	be	VBD
cord-342419-liaihahj	106	17	observed	observe	VBN
cord-342419-liaihahj	106	18	when	when	WRB
cord-342419-liaihahj	106	19	viewing	view	VBG
cord-342419-liaihahj	106	20	symmetry	symmetry	NN
cord-342419-liaihahj	106	21	related	relate	VBN
cord-342419-liaihahj	106	22	partners	partner	NNS
cord-342419-liaihahj	106	23	(	(	-LRB-
cord-342419-liaihahj	106	24	S6	S6	NNP
cord-342419-liaihahj	106	25	Fig	Fig	NNP
cord-342419-liaihahj	106	26	)	)	-RRB-
cord-342419-liaihahj	106	27	.	.	.
cord-342419-liaihahj	107	1	MPV458	MPV458	NNP
cord-342419-liaihahj	107	2	targets	target	VBZ
cord-342419-liaihahj	107	3	a	a	DT
cord-342419-liaihahj	107	4	unique	unique	JJ
cord-342419-liaihahj	107	5	epitope	epitope	NN
cord-342419-liaihahj	107	6	compared	compare	VBN
cord-342419-liaihahj	107	7	to	to	IN
cord-342419-liaihahj	107	8	previously	previously	RB
cord-342419-liaihahj	107	9	discovered	discover	VBN
cord-342419-liaihahj	107	10	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	107	11	antigenic	antigenic	JJ
cord-342419-liaihahj	107	12	sites	site	NNS
cord-342419-liaihahj	107	13	.	.	.
cord-342419-liaihahj	108	1	The	the	DT
cord-342419-liaihahj	108	2	primary	primary	JJ
cord-342419-liaihahj	108	3	epitope	epitope	NN
cord-342419-liaihahj	108	4	consists	consist	VBZ
cord-342419-liaihahj	108	5	of	of	IN
cord-342419-liaihahj	108	6	a	a	DT
cord-342419-liaihahj	108	7	single	single	JJ
cord-342419-liaihahj	108	8	alpha	alpha	NN
cord-342419-liaihahj	108	9	helix	helix	NN
cord-342419-liaihahj	108	10	of	of	IN
cord-342419-liaihahj	108	11	amino	amino	JJ
cord-342419-liaihahj	108	12	acids	acid	NNS
cord-342419-liaihahj	108	13	66	66	CD
cord-342419-liaihahj	108	14	-	-	SYM
cord-342419-liaihahj	108	15	87	87	CD
cord-342419-liaihahj	108	16	of	of	IN
cord-342419-liaihahj	108	17	the	the	DT
cord-342419-liaihahj	108	18	F2	f2	NN
cord-342419-liaihahj	108	19	region	region	NN
cord-342419-liaihahj	108	20	(	(	-LRB-
cord-342419-liaihahj	108	21	Fig	Fig	NNP
cord-342419-liaihahj	108	22	3A	3a	CD
cord-342419-liaihahj	108	23	)	)	-RRB-
cord-342419-liaihahj	108	24	.	.	.
cord-342419-liaihahj	109	1	Compared	compare	VBN
cord-342419-liaihahj	109	2	to	to	IN
cord-342419-liaihahj	109	3	the	the	DT
cord-342419-liaihahj	109	4	hMPV	hmpv	NN
cord-342419-liaihahj	109	5	F	F	NNP
cord-342419-liaihahj	109	6	protein	protein	NN
cord-342419-liaihahj	109	7	,	,	,
cord-342419-liaihahj	109	8	MPV458	MPV458	NNP
cord-342419-liaihahj	109	9	binds	bind	VBZ
cord-342419-liaihahj	109	10	nearly	nearly	RB
cord-342419-liaihahj	109	11	perpendicular	perpendicular	JJ
cord-342419-liaihahj	109	12	to	to	IN
cord-342419-liaihahj	109	13	the	the	DT
cord-342419-liaihahj	109	14	long	long	JJ
cord-342419-liaihahj	109	15	axis	axis	NN
cord-342419-liaihahj	109	16	of	of	IN
cord-342419-liaihahj	109	17	the	the	DT
cord-342419-liaihahj	109	18	F	F	NNP
cord-342419-liaihahj	109	19	protein	protein	NN
cord-342419-liaihahj	109	20	.	.	.
cord-342419-liaihahj	110	1	Upon	upon	IN
cord-342419-liaihahj	110	2	overlay	overlay	NN
cord-342419-liaihahj	110	3	with	with	IN
cord-342419-liaihahj	110	4	the	the	DT
cord-342419-liaihahj	110	5	previously	previously	RB
cord-342419-liaihahj	110	6	determined	determine	VBN
cord-342419-liaihahj	110	7	X	x	NN
cord-342419-liaihahj	110	8	-	-	NN
cord-342419-liaihahj	110	9	ray	ray	NN
cord-342419-liaihahj	110	10	crystal	crystal	NN
cord-342419-liaihahj	110	11	structure	structure	NN
cord-342419-liaihahj	110	12	of	of	IN
cord-342419-liaihahj	110	13	pre	pre	JJ
cord-342419-liaihahj	110	14	-	-	JJ
cord-342419-liaihahj	110	15	fusion	fusion	JJ
cord-342419-liaihahj	110	16	hMPV	hmpv	NN
cord-342419-liaihahj	110	17	F	F	NNP
cord-342419-liaihahj	110	18	,	,	,
cord-342419-liaihahj	110	19	it	-PRON-	PRP
cord-342419-liaihahj	110	20	is	be	VBZ
cord-342419-liaihahj	110	21	clear	clear	JJ
cord-342419-liaihahj	110	22	the	the	DT
cord-342419-liaihahj	110	23	major	major	JJ
cord-342419-liaihahj	110	24	epitope	epitope	NN
cord-342419-liaihahj	110	25	lies	lie	VBZ
cord-342419-liaihahj	110	26	completely	completely	RB
cord-342419-liaihahj	110	27	within	within	IN
cord-342419-liaihahj	110	28	the	the	DT
cord-342419-liaihahj	110	29	interface	interface	NN
cord-342419-liaihahj	110	30	between	between	IN
cord-342419-liaihahj	110	31	two	two	CD
cord-342419-liaihahj	110	32	protomers	protomer	NNS
cord-342419-liaihahj	110	33	of	of	IN
cord-342419-liaihahj	110	34	trimeric	trimeric	NNP
cord-342419-liaihahj	110	35	hMPV	hMPV	NNP
cord-342419-liaihahj	110	36	F	F	NNP
cord-342419-liaihahj	110	37	(	(	-LRB-
cord-342419-liaihahj	110	38	Fig	Fig	NNP
cord-342419-liaihahj	110	39	3B	3b	CD
cord-342419-liaihahj	110	40	)	)	-RRB-
cord-342419-liaihahj	110	41	.	.	.
cord-342419-liaihahj	111	1	This	this	DT
cord-342419-liaihahj	111	2	unusual	unusual	JJ
cord-342419-liaihahj	111	3	epitope	epitope	NN
cord-342419-liaihahj	111	4	suggests	suggest	VBZ
cord-342419-liaihahj	111	5	the	the	DT
cord-342419-liaihahj	111	6	hMPV	hmpv	NN
cord-342419-liaihahj	111	7	F	F	NNP
cord-342419-liaihahj	111	8	protein	protein	NN
cord-342419-liaihahj	111	9	is	be	VBZ
cord-342419-liaihahj	111	10	partially	partially	RB
cord-342419-liaihahj	111	11	monomeric	monomeric	JJ
cord-342419-liaihahj	111	12	on	on	IN
cord-342419-liaihahj	111	13	the	the	DT
cord-342419-liaihahj	111	14	surface	surface	NN
cord-342419-liaihahj	111	15	of	of	IN
cord-342419-liaihahj	111	16	the	the	DT
cord-342419-liaihahj	111	17	virion	virion	NN
cord-342419-liaihahj	111	18	envelope	envelope	NN
cord-342419-liaihahj	111	19	or	or	CC
cord-342419-liaihahj	111	20	on	on	IN
cord-342419-liaihahj	111	21	hMPV	hmpv	NN
cord-342419-liaihahj	111	22	infected	infected	JJ
cord-342419-liaihahj	111	23	cells	cell	NNS
cord-342419-liaihahj	111	24	,	,	,
cord-342419-liaihahj	111	25	and/or	and/or	CC
cord-342419-liaihahj	111	26	substantial	substantial	JJ
cord-342419-liaihahj	111	27	breathing	breathing	NN
cord-342419-liaihahj	111	28	of	of	IN
cord-342419-liaihahj	111	29	the	the	DT
cord-342419-liaihahj	111	30	hMPV	hmpv	NN
cord-342419-liaihahj	111	31	F	F	NNP
cord-342419-liaihahj	111	32	protein	protein	NN
cord-342419-liaihahj	111	33	takes	take	VBZ
cord-342419-liaihahj	111	34	place	place	NN
cord-342419-liaihahj	111	35	to	to	TO
cord-342419-liaihahj	111	36	allow	allow	VB
cord-342419-liaihahj	111	37	the	the	DT
cord-342419-liaihahj	111	38	antibody	antibody	NN
cord-342419-liaihahj	111	39	to	to	TO
cord-342419-liaihahj	111	40	bind	bind	VB
cord-342419-liaihahj	111	41	and	and	CC
cord-342419-liaihahj	111	42	neutralize	neutralize	VB
cord-342419-liaihahj	111	43	the	the	DT
cord-342419-liaihahj	111	44	virus	virus	NN
cord-342419-liaihahj	111	45	.	.	.
cord-342419-liaihahj	112	1	As	as	IN
cord-342419-liaihahj	112	2	mentioned	mention	VBN
cord-342419-liaihahj	112	3	earlier	early	RBR
cord-342419-liaihahj	112	4	,	,	,
cord-342419-liaihahj	112	5	MPV458	MPV458	NNP
cord-342419-liaihahj	112	6	has	have	VBZ
cord-342419-liaihahj	112	7	an	an	DT
cord-342419-liaihahj	112	8	unusually	unusually	RB
cord-342419-liaihahj	112	9	short	short	JJ
cord-342419-liaihahj	112	10	HCDR3	HCDR3	NNS
cord-342419-liaihahj	112	11	loop	loop	NN
cord-342419-liaihahj	112	12	of	of	IN
cord-342419-liaihahj	112	13	just	just	RB
cord-342419-liaihahj	112	14	8	8	CD
cord-342419-liaihahj	112	15	amino	amino	NN
cord-342419-liaihahj	112	16	acids	acid	NNS
cord-342419-liaihahj	112	17	.	.	.
cord-342419-liaihahj	113	1	The	the	DT
cord-342419-liaihahj	113	2	HCDR3	HCDR3	NNS
cord-342419-liaihahj	113	3	and	and	CC
cord-342419-liaihahj	113	4	light	light	JJ
cord-342419-liaihahj	113	5	chain	chain	NN
cord-342419-liaihahj	113	6	CDR	cdr	NN
cord-342419-liaihahj	113	7	(	(	-LRB-
cord-342419-liaihahj	113	8	LCDR	LCDR	NNP
cord-342419-liaihahj	113	9	)	)	-RRB-
cord-342419-liaihahj	114	1	3	3	CD
cord-342419-liaihahj	114	2	are	be	VBP
cord-342419-liaihahj	114	3	centered	center	VBN
cord-342419-liaihahj	114	4	on	on	IN
cord-342419-liaihahj	114	5	the	the	DT
cord-342419-liaihahj	114	6	66	66	CD
cord-342419-liaihahj	114	7	-	-	SYM
cord-342419-liaihahj	114	8	87	87	CD
cord-342419-liaihahj	114	9	helix	helix	NN
cord-342419-liaihahj	114	10	region	region	NN
cord-342419-liaihahj	114	11	.	.	.
cord-342419-liaihahj	115	1	Numerous	numerous	JJ
cord-342419-liaihahj	115	2	hydrogen	hydrogen	NN
cord-342419-liaihahj	115	3	bonding	bonding	NN
cord-342419-liaihahj	115	4	events	event	NNS
cord-342419-liaihahj	115	5	were	be	VBD
cord-342419-liaihahj	115	6	clear	clear	JJ
cord-342419-liaihahj	115	7	in	in	IN
cord-342419-liaihahj	115	8	the	the	DT
cord-342419-liaihahj	115	9	electron	electron	NN
cord-342419-liaihahj	115	10	density	density	NN
cord-342419-liaihahj	115	11	(	(	-LRB-
cord-342419-liaihahj	115	12	Fig	Fig	NNP
cord-342419-liaihahj	115	13	3C	3c	NN
cord-342419-liaihahj	115	14	;	;	:
cord-342419-liaihahj	115	15	Fig	Fig	NNP
cord-342419-liaihahj	115	16	3D	3d	NN
cord-342419-liaihahj	115	17	;	;	:
cord-342419-liaihahj	115	18	S7	S7	NNP
cord-342419-liaihahj	115	19	 	 	_SP
cord-342419-liaihahj	115	20	Fig	Fig	NNP
cord-342419-liaihahj	115	21	)	)	-RRB-
cord-342419-liaihahj	115	22	.	.	.
cord-342419-liaihahj	116	1	The	the	DT
cord-342419-liaihahj	116	2	HCDR3	HCDR3	NNS
cord-342419-liaihahj	116	3	interacts	interact	VBZ
cord-342419-liaihahj	116	4	via	via	IN
cord-342419-liaihahj	116	5	Asp107	asp107	NN
cord-342419-liaihahj	116	6	with	with	IN
cord-342419-liaihahj	116	7	Arg79	Arg79	NNP
cord-342419-liaihahj	116	8	of	of	IN
cord-342419-liaihahj	116	9	hMPV	hmpv	NN
cord-342419-liaihahj	116	10	F	F	NNP
cord-342419-liaihahj	116	11	,	,	,
cord-342419-liaihahj	116	12	while	while	IN
cord-342419-liaihahj	116	13	HCDR2	HCDR2	NNP
cord-342419-liaihahj	116	14	Asn64	Asn64	NNP
cord-342419-liaihahj	116	15	and	and	CC
cord-342419-liaihahj	116	16	Ser63	Ser63	NNP
cord-342419-liaihahj	116	17	interact	interact	VBP
cord-342419-liaihahj	116	18	with	with	IN
cord-342419-liaihahj	116	19	hMPV	hmpv	NN
cord-342419-liaihahj	116	20	F	F	NNP
cord-342419-liaihahj	116	21	Glu80	Glu80	NNP
cord-342419-liaihahj	116	22	and	and	CC
cord-342419-liaihahj	116	23	Arg205	arg205	CD
cord-342419-liaihahj	116	24	,	,	,
cord-342419-liaihahj	116	25	respectively	respectively	RB
cord-342419-liaihahj	116	26	(	(	-LRB-
cord-342419-liaihahj	116	27	Fig	Fig	NNP
cord-342419-liaihahj	116	28	3C	3c	NN
cord-342419-liaihahj	116	29	)	)	-RRB-
cord-342419-liaihahj	116	30	.	.	.
cord-342419-liaihahj	117	1	The	the	DT
cord-342419-liaihahj	117	2	HCDR1	HCDR1	NNP
cord-342419-liaihahj	117	3	utilizes	utilize	VBZ
cord-342419-liaihahj	117	4	Arg36	Arg36	NNP
cord-342419-liaihahj	117	5	to	to	TO
cord-342419-liaihahj	117	6	interact	interact	VB
cord-342419-liaihahj	117	7	with	with	IN
cord-342419-liaihahj	117	8	hMPV	hmpv	NN
cord-342419-liaihahj	117	9	F	F	NNP
cord-342419-liaihahj	117	10	Glu70	Glu70	NNP
cord-342419-liaihahj	117	11	.	.	.
cord-342419-liaihahj	118	1	The	the	DT
cord-342419-liaihahj	118	2	light	light	JJ
cord-342419-liaihahj	118	3	chain	chain	NN
cord-342419-liaihahj	118	4	LCDR3	LCDR3	NNS
cord-342419-liaihahj	118	5	has	have	VBZ
cord-342419-liaihahj	118	6	more	more	JJR
cord-342419-liaihahj	118	7	hydrogen	hydrogen	NN
cord-342419-liaihahj	118	8	bonding	bonding	NN
cord-342419-liaihahj	118	9	events	event	NNS
cord-342419-liaihahj	118	10	than	than	IN
cord-342419-liaihahj	118	11	the	the	DT
cord-342419-liaihahj	118	12	HCDR3	HCDR3	NNS
cord-342419-liaihahj	118	13	,	,	,
cord-342419-liaihahj	118	14	utilizing	utilize	VBG
cord-342419-liaihahj	118	15	the	the	DT
cord-342419-liaihahj	118	16	backbone	backbone	NN
cord-342419-liaihahj	118	17	amino	amino	NN
cord-342419-liaihahj	118	18	group	group	NN
cord-342419-liaihahj	118	19	of	of	IN
cord-342419-liaihahj	118	20	Leu114	leu114	PRP
cord-342419-liaihahj	118	21	to	to	TO
cord-342419-liaihahj	118	22	interact	interact	VB
cord-342419-liaihahj	118	23	with	with	IN
cord-342419-liaihahj	118	24	hMPV	hmpv	NN
cord-342419-liaihahj	118	25	F	F	NNP
cord-342419-liaihahj	118	26	Thr83	Thr83	NNP
cord-342419-liaihahj	118	27	,	,	,
cord-342419-liaihahj	119	1	Arg115	Arg115	NNP
cord-342419-liaihahj	119	2	to	to	TO
cord-342419-liaihahj	119	3	hMPV	hmpv	VB
cord-342419-liaihahj	119	4	F	F	NNP
cord-342419-liaihahj	119	5	Asp87	Asp87	NNP
cord-342419-liaihahj	119	6	,	,	,
cord-342419-liaihahj	119	7	and	and	CC
cord-342419-liaihahj	120	1	Asp108	Asp108	,
cord-342419-liaihahj	120	2	to	to	TO
cord-342419-liaihahj	120	3	hMPV	hmpv	VB
cord-342419-liaihahj	120	4	F	F	NNP
cord-342419-liaihahj	120	5	Lys82	Lys82	NNP
cord-342419-liaihahj	120	6	(	(	-LRB-
cord-342419-liaihahj	120	7	Fig	Fig	NNP
cord-342419-liaihahj	120	8	3D	3d	NN
cord-342419-liaihahj	120	9	)	)	-RRB-
cord-342419-liaihahj	120	10	.	.	.
cord-342419-liaihahj	121	1	LCDR1	lcdr1	XX
cord-342419-liaihahj	122	1	Arg37	Arg37	NNP
cord-342419-liaihahj	122	2	interacts	interact	VBZ
cord-342419-liaihahj	122	3	with	with	IN
cord-342419-liaihahj	122	4	hMPV	hmpv	NN
cord-342419-liaihahj	122	5	F	F	NNP
cord-342419-liaihahj	122	6	Asn57	Asn57	NNP
cord-342419-liaihahj	122	7	,	,	,
cord-342419-liaihahj	122	8	which	which	WDT
cord-342419-liaihahj	122	9	has	have	VBZ
cord-342419-liaihahj	122	10	an	an	DT
cord-342419-liaihahj	122	11	extended	extended	JJ
cord-342419-liaihahj	122	12	N	n	NN
cord-342419-liaihahj	122	13	-	-	HYPH
cord-342419-liaihahj	122	14	linked	link	VBN
cord-342419-liaihahj	122	15	glycan	glycan	NN
cord-342419-liaihahj	122	16	motif	motif	NN
cord-342419-liaihahj	122	17	.	.	.
cord-342419-liaihahj	123	1	In	in	IN
cord-342419-liaihahj	123	2	addition	addition	NN
cord-342419-liaihahj	123	3	,	,	,
cord-342419-liaihahj	123	4	the	the	DT
cord-342419-liaihahj	123	5	LCDR2	lcdr2	NN
cord-342419-liaihahj	123	6	Asp56	Asp56	NNP
cord-342419-liaihahj	123	7	interacts	interact	VBZ
cord-342419-liaihahj	123	8	with	with	IN
cord-342419-liaihahj	123	9	hMPV	hmpv	NN
cord-342419-liaihahj	123	10	F	F	NNP
cord-342419-liaihahj	123	11	Thr56	Thr56	NNP
cord-342419-liaihahj	123	12	.	.	.
cord-342419-liaihahj	124	1	The	the	DT
cord-342419-liaihahj	124	2	Framework	Framework	NNP
cord-342419-liaihahj	124	3	3	3	CD
cord-342419-liaihahj	124	4	loop	loop	NN
cord-342419-liaihahj	124	5	of	of	IN
cord-342419-liaihahj	124	6	the	the	DT
cord-342419-liaihahj	124	7	light	light	JJ
cord-342419-liaihahj	124	8	chain	chain	NN
cord-342419-liaihahj	124	9	interacts	interact	VBZ
cord-342419-liaihahj	124	10	with	with	IN
cord-342419-liaihahj	124	11	the	the	DT
cord-342419-liaihahj	124	12	glycan	glycan	NN
cord-342419-liaihahj	124	13	motif	motif	NN
cord-342419-liaihahj	124	14	consisting	consist	VBG
cord-342419-liaihahj	124	15	of	of	IN
cord-342419-liaihahj	124	16	NAG	NAG	NNP
cord-342419-liaihahj	124	17	-	-	HYPH
cord-342419-liaihahj	124	18	NAG	NAG	NNP
cord-342419-liaihahj	124	19	-	-	HYPH
cord-342419-liaihahj	124	20	BMA	BMA	NNP
cord-342419-liaihahj	124	21	with	with	IN
cord-342419-liaihahj	124	22	branched	branched	JJ
cord-342419-liaihahj	124	23	MAN	man	NN
cord-342419-liaihahj	124	24	residues	residue	NNS
cord-342419-liaihahj	124	25	off	off	IN
cord-342419-liaihahj	124	26	the	the	DT
cord-342419-liaihahj	124	27	BMA	BMA	NNP
cord-342419-liaihahj	124	28	glycan	glycan	NN
cord-342419-liaihahj	124	29	,	,	,
cord-342419-liaihahj	124	30	in	in	IN
cord-342419-liaihahj	124	31	which	which	WDT
cord-342419-liaihahj	124	32	Tyr83	Tyr83	NNP
cord-342419-liaihahj	124	33	interacts	interact	VBZ
cord-342419-liaihahj	124	34	with	with	IN
cord-342419-liaihahj	124	35	the	the	DT
cord-342419-liaihahj	124	36	extended	extended	JJ
cord-342419-liaihahj	124	37	MAN	man	NN
cord-342419-liaihahj	124	38	glycan	glycan	NN
cord-342419-liaihahj	124	39	,	,	,
cord-342419-liaihahj	124	40	while	while	IN
cord-342419-liaihahj	124	41	the	the	DT
cord-342419-liaihahj	124	42	long	long	JJ
cord-342419-liaihahj	124	43	-	-	HYPH
cord-342419-liaihahj	124	44	face	face	NN
cord-342419-liaihahj	124	45	of	of	IN
cord-342419-liaihahj	124	46	Tyr83	Tyr83	NNP
cord-342419-liaihahj	124	47	sits	sit	VBZ
cord-342419-liaihahj	124	48	parallel	parallel	JJ
cord-342419-liaihahj	124	49	to	to	IN
cord-342419-liaihahj	124	50	the	the	DT
cord-342419-liaihahj	124	51	extended	extend	VBN
cord-342419-liaihahj	124	52	glycan	glycan	NN
cord-342419-liaihahj	124	53	,	,	,
cord-342419-liaihahj	124	54	suggesting	suggest	VBG
cord-342419-liaihahj	124	55	a	a	DT
cord-342419-liaihahj	124	56	favorable	favorable	JJ
cord-342419-liaihahj	124	57	interaction	interaction	NN
cord-342419-liaihahj	124	58	with	with	IN
cord-342419-liaihahj	124	59	the	the	DT
cord-342419-liaihahj	124	60	glycan	glycan	NN
cord-342419-liaihahj	124	61	motif	motif	NN
cord-342419-liaihahj	124	62	.	.	.
cord-342419-liaihahj	125	1	The	the	DT
cord-342419-liaihahj	125	2	66	66	CD
cord-342419-liaihahj	125	3	-	-	SYM
cord-342419-liaihahj	125	4	87	87	CD
cord-342419-liaihahj	125	5	helix	helix	NN
cord-342419-liaihahj	125	6	of	of	IN
cord-342419-liaihahj	125	7	hMPV	hmpv	NN
cord-342419-liaihahj	125	8	F	F	NNP
cord-342419-liaihahj	125	9	is	be	VBZ
cord-342419-liaihahj	125	10	structurally	structurally	RB
cord-342419-liaihahj	125	11	conserved	conserve	VBN
cord-342419-liaihahj	125	12	in	in	IN
cord-342419-liaihahj	125	13	the	the	DT
cord-342419-liaihahj	125	14	pre	pre	JJ
cord-342419-liaihahj	125	15	-	-	JJ
cord-342419-liaihahj	125	16	fusion	fusion	JJ
cord-342419-liaihahj	125	17	and	and	CC
cord-342419-liaihahj	125	18	post	post	JJ
cord-342419-liaihahj	125	19	-	-	JJ
cord-342419-liaihahj	125	20	fusion	fusion	JJ
cord-342419-liaihahj	125	21	conformations	conformation	NNS
cord-342419-liaihahj	125	22	,	,	,
cord-342419-liaihahj	125	23	although	although	IN
cord-342419-liaihahj	125	24	the	the	DT
cord-342419-liaihahj	125	25	helix	helix	NN
cord-342419-liaihahj	125	26	is	be	VBZ
cord-342419-liaihahj	125	27	exposed	expose	VBN
cord-342419-liaihahj	125	28	on	on	IN
cord-342419-liaihahj	125	29	the	the	DT
cord-342419-liaihahj	125	30	outer	outer	JJ
cord-342419-liaihahj	125	31	surface	surface	NN
cord-342419-liaihahj	125	32	in	in	IN
cord-342419-liaihahj	125	33	the	the	DT
cord-342419-liaihahj	125	34	trimeric	trimeric	JJ
cord-342419-liaihahj	125	35	post	post	JJ
cord-342419-liaihahj	125	36	-	-	JJ
cord-342419-liaihahj	125	37	fusion	fusion	JJ
cord-342419-liaihahj	125	38	conformation	conformation	NN
cord-342419-liaihahj	125	39	(	(	-LRB-
cord-342419-liaihahj	125	40	Fig	fig	NN
cord-342419-liaihahj	125	41	4A	4a	CD
cord-342419-liaihahj	125	42	;	;	:
cord-342419-liaihahj	125	43	Fig	Fig	NNP
cord-342419-liaihahj	125	44	4B	4b	CD
cord-342419-liaihahj	125	45	)	)	-RRB-
cord-342419-liaihahj	125	46	.	.	.
cord-342419-liaihahj	126	1	Upon	upon	IN
cord-342419-liaihahj	126	2	overlay	overlay	NN
cord-342419-liaihahj	126	3	of	of	IN
cord-342419-liaihahj	126	4	the	the	DT
cord-342419-liaihahj	126	5	66	66	CD
cord-342419-liaihahj	126	6	-	-	SYM
cord-342419-liaihahj	126	7	87	87	CD
cord-342419-liaihahj	126	8	region	region	NN
cord-342419-liaihahj	126	9	of	of	IN
cord-342419-liaihahj	126	10	the	the	DT
cord-342419-liaihahj	126	11	pre	pre	JJ
cord-342419-liaihahj	126	12	-	-	JJ
cord-342419-liaihahj	126	13	fusion	fusion	JJ
cord-342419-liaihahj	126	14	and	and	CC
cord-342419-liaihahj	126	15	post	post	JJ
cord-342419-liaihahj	126	16	-	-	JJ
cord-342419-liaihahj	126	17	fusion	fusion	JJ
cord-342419-liaihahj	126	18	hMPV	hmpv	NN
cord-342419-liaihahj	126	19	F	F	NNP
cord-342419-liaihahj	126	20	proteins	protein	NNS
cord-342419-liaihahj	126	21	,	,	,
cord-342419-liaihahj	126	22	residues	residue	VBZ
cord-342419-liaihahj	126	23	66	66	CD
cord-342419-liaihahj	126	24	-	-	SYM
cord-342419-liaihahj	126	25	83	83	CD
cord-342419-liaihahj	126	26	align	align	NN
cord-342419-liaihahj	126	27	well	well	RB
cord-342419-liaihahj	126	28	,	,	,
cord-342419-liaihahj	126	29	while	while	IN
cord-342419-liaihahj	126	30	the	the	DT
cord-342419-liaihahj	126	31	helix	helix	NN
cord-342419-liaihahj	126	32	breaks	break	VBZ
cord-342419-liaihahj	126	33	on	on	IN
cord-342419-liaihahj	126	34	post	post	JJ
cord-342419-liaihahj	126	35	-	-	JJ
cord-342419-liaihahj	126	36	fusion	fusion	JJ
cord-342419-liaihahj	126	37	hMPV	hmpv	NN
cord-342419-liaihahj	126	38	F	F	NNP
cord-342419-liaihahj	126	39	at	at	IN
cord-342419-liaihahj	126	40	residues	residue	NNS
cord-342419-liaihahj	126	41	84	84	CD
cord-342419-liaihahj	126	42	-	-	SYM
cord-342419-liaihahj	126	43	87	87	CD
cord-342419-liaihahj	127	1	(	(	-LRB-
cord-342419-liaihahj	127	2	Fig	Fig	NNP
cord-342419-liaihahj	127	3	4C	4c	CD
cord-342419-liaihahj	127	4	)	)	-RRB-
cord-342419-liaihahj	127	5	.	.	.
cord-342419-liaihahj	128	1	This	this	DT
cord-342419-liaihahj	128	2	sequence	sequence	NN
cord-342419-liaihahj	128	3	identity	identity	NN
cord-342419-liaihahj	128	4	of	of	IN
cord-342419-liaihahj	128	5	the	the	DT
cord-342419-liaihahj	128	6	helix	helix	NN
cord-342419-liaihahj	128	7	is	be	VBZ
cord-342419-liaihahj	128	8	highly	highly	RB
cord-342419-liaihahj	128	9	conserved	conserve	VBN
cord-342419-liaihahj	128	10	,	,	,
cord-342419-liaihahj	128	11	as	as	IN
cord-342419-liaihahj	128	12	residues	residue	NNS
cord-342419-liaihahj	128	13	are	be	VBP
cord-342419-liaihahj	128	14	identical	identical	JJ
cord-342419-liaihahj	128	15	between	between	IN
cord-342419-liaihahj	128	16	the	the	DT
cord-342419-liaihahj	128	17	A1	A1	NNP
cord-342419-liaihahj	128	18	and	and	CC
cord-342419-liaihahj	128	19	B2	b2	NN
cord-342419-liaihahj	128	20	subgroups	subgroup	NNS
cord-342419-liaihahj	128	21	,	,	,
cord-342419-liaihahj	128	22	except	except	IN
cord-342419-liaihahj	128	23	for	for	IN
cord-342419-liaihahj	128	24	a	a	DT
cord-342419-liaihahj	128	25	Lys82	Lys82	NNP
cord-342419-liaihahj	128	26	/	/	SYM
cord-342419-liaihahj	128	27	Arg82	Arg82	NNP
cord-342419-liaihahj	128	28	mutation	mutation	NN
cord-342419-liaihahj	128	29	.	.	.
cord-342419-liaihahj	129	1	As	as	IN
cord-342419-liaihahj	129	2	MPV458	MPV458	NNP
cord-342419-liaihahj	129	3	and	and	CC
cord-342419-liaihahj	129	4	MPV465	MPV465	NNP
cord-342419-liaihahj	129	5	exhibited	exhibit	VBD
cord-342419-liaihahj	129	6	binding	bind	VBG
cord-342419-liaihahj	129	7	to	to	IN
cord-342419-liaihahj	129	8	post	post	JJ
cord-342419-liaihahj	129	9	-	-	JJ
cord-342419-liaihahj	129	10	fusion	fusion	JJ
cord-342419-liaihahj	129	11	hMPV	hmpv	NN
cord-342419-liaihahj	129	12	F	F	NNP
cord-342419-liaihahj	129	13	constructs	construct	NNS
cord-342419-liaihahj	129	14	,	,	,
cord-342419-liaihahj	129	15	we	-PRON-	PRP
cord-342419-liaihahj	129	16	further	further	RB
cord-342419-liaihahj	129	17	examined	examine	VBD
cord-342419-liaihahj	129	18	binding	bind	VBG
cord-342419-liaihahj	129	19	by	by	IN
cord-342419-liaihahj	129	20	attempting	attempt	VBG
cord-342419-liaihahj	129	21	to	to	TO
cord-342419-liaihahj	129	22	generate	generate	VB
cord-342419-liaihahj	129	23	a	a	DT
cord-342419-liaihahj	129	24	complex	complex	NN
cord-342419-liaihahj	129	25	between	between	IN
cord-342419-liaihahj	129	26	the	the	DT
cord-342419-liaihahj	129	27	Fab	Fab	NNP
cord-342419-liaihahj	129	28	of	of	IN
cord-342419-liaihahj	129	29	MPV458	MPV458	NNP
cord-342419-liaihahj	129	30	and	and	CC
cord-342419-liaihahj	129	31	trypsinized	trypsinize	VBD
cord-342419-liaihahj	129	32	hMPV	hmpv	NN
cord-342419-liaihahj	129	33	B2	b2	NN
cord-342419-liaihahj	129	34	F	F	NNP
cord-342419-liaihahj	129	35	that	that	WDT
cord-342419-liaihahj	129	36	was	be	VBD
cord-342419-liaihahj	129	37	in	in	IN
cord-342419-liaihahj	129	38	the	the	DT
cord-342419-liaihahj	129	39	post	post	JJ
cord-342419-liaihahj	129	40	-	-	JJ
cord-342419-liaihahj	129	41	fusion	fusion	JJ
cord-342419-liaihahj	129	42	conformation	conformation	NN
cord-342419-liaihahj	129	43	(	(	-LRB-
cord-342419-liaihahj	129	44	S2	S2	NNP
cord-342419-liaihahj	129	45	Fig	Fig	NNP
cord-342419-liaihahj	129	46	;	;	:
cord-342419-liaihahj	129	47	S8	S8	NNP
cord-342419-liaihahj	129	48	Fig	Fig	NNP
cord-342419-liaihahj	129	49	)	)	-RRB-
cord-342419-liaihahj	129	50	.	.	.
cord-342419-liaihahj	130	1	No	no	DT
cord-342419-liaihahj	130	2	complex	complex	NN
cord-342419-liaihahj	130	3	was	be	VBD
cord-342419-liaihahj	130	4	observed	observe	VBN
cord-342419-liaihahj	130	5	as	as	IN
cord-342419-liaihahj	130	6	assessed	assess	VBN
cord-342419-liaihahj	130	7	by	by	IN
cord-342419-liaihahj	130	8	size	size	NN
cord-342419-liaihahj	130	9	exclusion	exclusion	NN
cord-342419-liaihahj	130	10	chromatography	chromatography	NN
cord-342419-liaihahj	130	11	,	,	,
cord-342419-liaihahj	130	12	while	while	IN
cord-342419-liaihahj	130	13	the	the	DT
cord-342419-liaihahj	130	14	Fab	Fab	NNP
cord-342419-liaihahj	130	15	of	of	IN
cord-342419-liaihahj	130	16	101F	101F	NNP
cord-342419-liaihahj	130	17	readily	readily	RB
cord-342419-liaihahj	130	18	formed	form	VBD
cord-342419-liaihahj	130	19	a	a	DT
cord-342419-liaihahj	130	20	complex	complex	NN
cord-342419-liaihahj	130	21	with	with	IN
cord-342419-liaihahj	130	22	the	the	DT
cord-342419-liaihahj	130	23	post	post	JJ
cord-342419-liaihahj	130	24	-	-	JJ
cord-342419-liaihahj	130	25	fusion	fusion	JJ
cord-342419-liaihahj	130	26	hMPV	hmpv	NN
cord-342419-liaihahj	130	27	F	F	NNP
cord-342419-liaihahj	130	28	protein	protein	NN
cord-342419-liaihahj	130	29	.	.	.
cord-342419-liaihahj	131	1	This	this	DT
cord-342419-liaihahj	131	2	suggests	suggest	VBZ
cord-342419-liaihahj	131	3	that	that	IN
cord-342419-liaihahj	131	4	although	although	IN
cord-342419-liaihahj	131	5	binding	bind	VBG
cord-342419-liaihahj	131	6	is	be	VBZ
cord-342419-liaihahj	131	7	observed	observe	VBN
cord-342419-liaihahj	131	8	by	by	IN
cord-342419-liaihahj	131	9	ELISA	ELISA	NNP
cord-342419-liaihahj	131	10	,	,	,
cord-342419-liaihahj	131	11	part	part	NN
cord-342419-liaihahj	131	12	of	of	IN
cord-342419-liaihahj	131	13	the	the	DT
cord-342419-liaihahj	131	14	epitope	epitope	NN
cord-342419-liaihahj	131	15	lies	lie	VBZ
cord-342419-liaihahj	131	16	outside	outside	IN
cord-342419-liaihahj	131	17	the	the	DT
cord-342419-liaihahj	131	18	66	66	CD
cord-342419-liaihahj	131	19	-	-	SYM
cord-342419-liaihahj	131	20	87	87	CD
cord-342419-liaihahj	131	21	helix	helix	NN
cord-342419-liaihahj	131	22	and	and	CC
cord-342419-liaihahj	131	23	is	be	VBZ
cord-342419-liaihahj	131	24	incomplete	incomplete	JJ
cord-342419-liaihahj	131	25	in	in	IN
cord-342419-liaihahj	131	26	the	the	DT
cord-342419-liaihahj	131	27	post	post	JJ
cord-342419-liaihahj	131	28	-	-	JJ
cord-342419-liaihahj	131	29	fusion	fusion	JJ
cord-342419-liaihahj	131	30	conformation	conformation	NN
cord-342419-liaihahj	131	31	.	.	.
cord-342419-liaihahj	132	1	Since	since	IN
cord-342419-liaihahj	132	2	the	the	DT
cord-342419-liaihahj	132	3	major	major	JJ
cord-342419-liaihahj	132	4	epitope	epitope	NN
cord-342419-liaihahj	132	5	is	be	VBZ
cord-342419-liaihahj	132	6	focused	focus	VBN
cord-342419-liaihahj	132	7	on	on	IN
cord-342419-liaihahj	132	8	the	the	DT
cord-342419-liaihahj	132	9	single	single	JJ
cord-342419-liaihahj	132	10	helix	helix	NN
cord-342419-liaihahj	132	11	,	,	,
cord-342419-liaihahj	132	12	we	-PRON-	PRP
cord-342419-liaihahj	132	13	assessed	assess	VBD
cord-342419-liaihahj	132	14	binding	bind	VBG
cord-342419-liaihahj	132	15	by	by	IN
cord-342419-liaihahj	132	16	western	western	JJ
cord-342419-liaihahj	132	17	blot	blot	NN
cord-342419-liaihahj	132	18	to	to	TO
cord-342419-liaihahj	132	19	determine	determine	VB
cord-342419-liaihahj	132	20	if	if	IN
cord-342419-liaihahj	132	21	MPV458	MPV458	NNP
cord-342419-liaihahj	132	22	displayed	display	VBD
cord-342419-liaihahj	132	23	binding	bind	VBG
cord-342419-liaihahj	132	24	to	to	IN
cord-342419-liaihahj	132	25	a	a	DT
cord-342419-liaihahj	132	26	linear	linear	JJ
cord-342419-liaihahj	132	27	conformation	conformation	NN
cord-342419-liaihahj	132	28	in	in	IN
cord-342419-liaihahj	132	29	the	the	DT
cord-342419-liaihahj	132	30	control	control	NN
cord-342419-liaihahj	132	31	.	.	.
cord-342419-liaihahj	133	1	Data	data	NN
cord-342419-liaihahj	133	2	points	point	NNS
cord-342419-liaihahj	133	3	are	be	VBP
cord-342419-liaihahj	133	4	the	the	DT
cord-342419-liaihahj	133	5	average	average	NN
cord-342419-liaihahj	133	6	of	of	IN
cord-342419-liaihahj	133	7	three	three	CD
cord-342419-liaihahj	133	8	replicates	replicate	NNS
cord-342419-liaihahj	133	9	and	and	CC
cord-342419-liaihahj	133	10	error	error	NN
cord-342419-liaihahj	133	11	bars	bar	NNS
cord-342419-liaihahj	133	12	are	be	VBP
cord-342419-liaihahj	133	13	95	95	CD
cord-342419-liaihahj	133	14	%	%	NN
cord-342419-liaihahj	133	15	confidence	confidence	NN
cord-342419-liaihahj	133	16	intervals	interval	NNS
cord-342419-liaihahj	133	17	.	.	.
cord-342419-liaihahj	134	1	Data	datum	NNS
cord-342419-liaihahj	134	2	are	be	VBP
cord-342419-liaihahj	134	3	shown	show	VBN
cord-342419-liaihahj	134	4	from	from	IN
cord-342419-liaihahj	134	5	one	one	CD
cord-342419-liaihahj	134	6	experiment	experiment	NN
cord-342419-liaihahj	134	7	and	and	CC
cord-342419-liaihahj	134	8	are	be	VBP
cord-342419-liaihahj	134	9	representative	representative	JJ
cord-342419-liaihahj	134	10	of	of	IN
cord-342419-liaihahj	134	11	two	two	CD
cord-342419-liaihahj	134	12	independent	independent	JJ
cord-342419-liaihahj	134	13	experiments	experiment	NNS
cord-342419-liaihahj	134	14	.	.	.
cord-342419-liaihahj	135	1	A	a	DT
cord-342419-liaihahj	135	2	mAb	mab	NN
cord-342419-liaihahj	135	3	was	be	VBD
cord-342419-liaihahj	135	4	considered	consider	VBN
cord-342419-liaihahj	135	5	neutralizing	neutralize	VBG
cord-342419-liaihahj	135	6	if	if	IN
cord-342419-liaihahj	135	7	>	>	XX
cord-342419-liaihahj	135	8	50	50	CD
cord-342419-liaihahj	135	9	%	%	NN
cord-342419-liaihahj	135	10	plaque	plaque	NN
cord-342419-liaihahj	135	11	reduction	reduction	NN
cord-342419-liaihahj	135	12	was	be	VBD
cord-342419-liaihahj	135	13	observed	observe	VBN
cord-342419-liaihahj	135	14	at	at	IN
cord-342419-liaihahj	135	15	the	the	DT
cord-342419-liaihahj	135	16	highest	high	JJS
cord-342419-liaihahj	135	17	concentration	concentration	NN
cord-342419-liaihahj	135	18	.	.	.
cord-342419-liaihahj	136	1	https://doi.org/10.1371/journal.ppat.1008942.g001	https://doi.org/10.1371/journal.ppat.1008942.g001	.
cord-342419-liaihahj	137	1	Antibody	antibody	NN
cord-342419-liaihahj	137	2	recognition	recognition	NN
cord-342419-liaihahj	137	3	of	of	IN
cord-342419-liaihahj	137	4	the	the	DT
cord-342419-liaihahj	137	5	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	137	6	fusion	fusion	NN
cord-342419-liaihahj	137	7	protein	protein	NN
cord-342419-liaihahj	137	8	trimer	trimer	NN
cord-342419-liaihahj	137	9	interface	interface	NN
cord-342419-liaihahj	137	10	MPV458	MPV458	NNP
cord-342419-liaihahj	137	11	and	and	CC
cord-342419-liaihahj	137	12	MPV465	MPV465	NNP
cord-342419-liaihahj	137	13	have	have	VB
cord-342419-liaihahj	137	14	lower	low	JJR
cord-342419-liaihahj	137	15	EC	EC	NNP
cord-342419-liaihahj	137	16	50	50	CD
cord-342419-liaihahj	137	17	values	value	NNS
cord-342419-liaihahj	137	18	(	(	-LRB-
cord-342419-liaihahj	137	19	higher	high	JJR
cord-342419-liaihahj	137	20	affinity	affinity	NN
cord-342419-liaihahj	137	21	)	)	-RRB-
cord-342419-liaihahj	137	22	for	for	IN
cord-342419-liaihahj	137	23	monomeric	monomeric	JJ
cord-342419-liaihahj	137	24	hMPV	hmpv	NN
cord-342419-liaihahj	137	25	B2	b2	NN
cord-342419-liaihahj	137	26	F	F	NNP
cord-342419-liaihahj	137	27	than	than	IN
cord-342419-liaihahj	137	28	trimeric	trimeric	NNP
cord-342419-liaihahj	137	29	hMPV	hmpv	NN
cord-342419-liaihahj	137	30	B2	b2	NN
cord-342419-liaihahj	137	31	F.	F.	NNP
cord-342419-liaihahj	137	32	MPV458	MPV458	NNP
cord-342419-liaihahj	137	33	and	and	CC
cord-342419-liaihahj	137	34	MPV465	MPV465	NNP
cord-342419-liaihahj	137	35	bind	bind	NN
cord-342419-liaihahj	137	36	to	to	TO
cord-342419-liaihahj	137	37	hMPV	hmpv	VB
cord-342419-liaihahj	137	38	F	F	NNP
cord-342419-liaihahj	137	39	proteins	protein	NNS
cord-342419-liaihahj	137	40	from	from	IN
cord-342419-liaihahj	137	41	all	all	DT
cord-342419-liaihahj	137	42	four	four	CD
cord-342419-liaihahj	137	43	subgroups	subgroup	NNS
cord-342419-liaihahj	137	44	.	.	.
cord-342419-liaihahj	138	1	Data	data	NN
cord-342419-liaihahj	138	2	points	point	NNS
cord-342419-liaihahj	138	3	are	be	VBP
cord-342419-liaihahj	138	4	the	the	DT
cord-342419-liaihahj	138	5	average	average	NN
cord-342419-liaihahj	138	6	of	of	IN
cord-342419-liaihahj	138	7	four	four	CD
cord-342419-liaihahj	138	8	replicates	replicate	NNS
cord-342419-liaihahj	138	9	and	and	CC
cord-342419-liaihahj	138	10	error	error	NN
cord-342419-liaihahj	138	11	bars	bar	NNS
cord-342419-liaihahj	138	12	are	be	VBP
cord-342419-liaihahj	138	13	95	95	CD
cord-342419-liaihahj	138	14	%	%	NN
cord-342419-liaihahj	138	15	confidence	confidence	NN
cord-342419-liaihahj	138	16	intervals	interval	NNS
cord-342419-liaihahj	138	17	.	.	.
cord-342419-liaihahj	139	1	>	>	XX
cord-342419-liaihahj	139	2	indicates	indicate	VBZ
cord-342419-liaihahj	139	3	the	the	DT
cord-342419-liaihahj	139	4	calculated	calculate	VBN
cord-342419-liaihahj	139	5	EC	EC	NNP
cord-342419-liaihahj	139	6	50	50	CD
cord-342419-liaihahj	139	7	was	be	VBD
cord-342419-liaihahj	139	8	either	either	CC
cord-342419-liaihahj	139	9	not	not	RB
cord-342419-liaihahj	139	10	in	in	IN
cord-342419-liaihahj	139	11	the	the	DT
cord-342419-liaihahj	139	12	range	range	NN
cord-342419-liaihahj	139	13	of	of	IN
cord-342419-liaihahj	139	14	the	the	DT
cord-342419-liaihahj	139	15	curve	curve	NN
cord-342419-liaihahj	139	16	(	(	-LRB-
cord-342419-liaihahj	139	17	due	due	IN
cord-342419-liaihahj	139	18	to	to	IN
cord-342419-liaihahj	139	19	an	an	DT
cord-342419-liaihahj	139	20	overall	overall	JJ
cord-342419-liaihahj	139	21	low	low	JJ
cord-342419-liaihahj	139	22	signal	signal	NN
cord-342419-liaihahj	139	23	)	)	-RRB-
cord-342419-liaihahj	139	24	or	or	CC
cord-342419-liaihahj	139	25	a	a	DT
cord-342419-liaihahj	139	26	signal	signal	NN
cord-342419-liaihahj	139	27	above	above	IN
cord-342419-liaihahj	139	28	0.5	0.5	CD
cord-342419-liaihahj	139	29	absorbance	absorbance	NN
cord-342419-liaihahj	139	30	units	unit	NNS
cord-342419-liaihahj	139	31	was	be	VBD
cord-342419-liaihahj	139	32	not	not	RB
cord-342419-liaihahj	139	33	detected	detect	VBN
cord-342419-liaihahj	139	34	at	at	IN
cord-342419-liaihahj	139	35	the	the	DT
cord-342419-liaihahj	139	36	highest	high	JJS
cord-342419-liaihahj	139	37	concentration	concentration	NN
cord-342419-liaihahj	139	38	of	of	IN
cord-342419-liaihahj	139	39	20	20	CD
cord-342419-liaihahj	139	40	μg/	μg/	NN
cord-342419-liaihahj	140	1	mL.	mL.	NNP
cord-342419-liaihahj	140	2	Each	each	DT
cord-342419-liaihahj	140	3	data	datum	NNS
cord-342419-liaihahj	140	4	point	point	NN
cord-342419-liaihahj	140	5	is	be	VBZ
cord-342419-liaihahj	140	6	the	the	DT
cord-342419-liaihahj	140	7	average	average	NN
cord-342419-liaihahj	140	8	of	of	IN
cord-342419-liaihahj	140	9	four	four	CD
cord-342419-liaihahj	140	10	replicates	replicate	NNS
cord-342419-liaihahj	140	11	and	and	CC
cord-342419-liaihahj	140	12	error	error	NN
cord-342419-liaihahj	140	13	bars	bar	NNS
cord-342419-liaihahj	140	14	represent	represent	VBP
cord-342419-liaihahj	140	15	95	95	CD
cord-342419-liaihahj	140	16	%	%	NN
cord-342419-liaihahj	140	17	confidence	confidence	NN
cord-342419-liaihahj	140	18	intervals	interval	NNS
cord-342419-liaihahj	140	19	.	.	.
cord-342419-liaihahj	141	1	Data	datum	NNS
cord-342419-liaihahj	141	2	are	be	VBP
cord-342419-liaihahj	141	3	representative	representative	JJ
cord-342419-liaihahj	141	4	of	of	IN
cord-342419-liaihahj	141	5	one	one	CD
cord-342419-liaihahj	141	6	experiment	experiment	NN
cord-342419-liaihahj	141	7	from	from	IN
cord-342419-liaihahj	141	8	two	two	CD
cord-342419-liaihahj	141	9	independent	independent	JJ
cord-342419-liaihahj	141	10	experiments	experiment	NNS
cord-342419-liaihahj	141	11	.	.	.
cord-342419-liaihahj	142	1	(	(	-LRB-
cord-342419-liaihahj	142	2	B	b	NN
cord-342419-liaihahj	142	3	)	)	-RRB-
cord-342419-liaihahj	142	4	Binding	bind	VBG
cord-342419-liaihahj	142	5	curves	curve	NNS
cord-342419-liaihahj	142	6	from	from	IN
cord-342419-liaihahj	142	7	biolayer	biolayer	NN
cord-342419-liaihahj	142	8	interferometry	interferometry	NN
cord-342419-liaihahj	142	9	.	.	.
cord-342419-liaihahj	143	1	Biotinylated	Biotinylated	NNP
cord-342419-liaihahj	143	2	monomeric	monomeric	JJ
cord-342419-liaihahj	143	3	hMPV	hmpv	NN
cord-342419-liaihahj	143	4	B2	b2	NN
cord-342419-liaihahj	143	5	F	F	NNP
cord-342419-liaihahj	143	6	protein	protein	NN
cord-342419-liaihahj	143	7	coated	coat	VBD
cord-342419-liaihahj	143	8	streptavidin	streptavidin	NNS
cord-342419-liaihahj	143	9	biosensors	biosensor	NNS
cord-342419-liaihahj	143	10	were	be	VBD
cord-342419-liaihahj	143	11	exposed	expose	VBN
cord-342419-liaihahj	143	12	to	to	IN
cord-342419-liaihahj	143	13	Fabs	fab	NNS
cord-342419-liaihahj	143	14	(	(	-LRB-
cord-342419-liaihahj	143	15	MPV458	MPV458	NNP
cord-342419-liaihahj	143	16	and	and	CC
cord-342419-liaihahj	143	17	MPV465	MPV465	NNP
cord-342419-liaihahj	143	18	:	:	:
cord-342419-liaihahj	143	19	10/5/1/	10/5/1/	CD
cord-342419-liaihahj	143	20	0.5	0.5	CD
cord-342419-liaihahj	143	21	μg	μg	NN
cord-342419-liaihahj	143	22	/	/	SYM
cord-342419-liaihahj	143	23	mL	mL	NNP
cord-342419-liaihahj	143	24	,	,	,
cord-342419-liaihahj	143	25	101F	101f	CD
cord-342419-liaihahj	143	26	:	:	:
cord-342419-liaihahj	143	27	100/75/50/25	100/75/50/25	CD
cord-342419-liaihahj	143	28	μg	μg	NNP
cord-342419-liaihahj	143	29	/	/	SYM
cord-342419-liaihahj	143	30	mL	mL	NNP
cord-342419-liaihahj	143	31	)	)	-RRB-
cord-342419-liaihahj	143	32	for	for	IN
cord-342419-liaihahj	143	33	300	300	CD
cord-342419-liaihahj	143	34	s	s	NNS
cord-342419-liaihahj	143	35	before	before	IN
cord-342419-liaihahj	143	36	dissociating	dissociate	VBG
cord-342419-liaihahj	143	37	in	in	IN
cord-342419-liaihahj	143	38	buffer	buffer	NN
cord-342419-liaihahj	143	39	for	for	IN
cord-342419-liaihahj	143	40	600	600	CD
cord-342419-liaihahj	143	41	s.	s.	NN
cord-342419-liaihahj	143	42	Binding	binding	NN
cord-342419-liaihahj	143	43	constants	constant	NNS
cord-342419-liaihahj	143	44	are	be	VBP
cord-342419-liaihahj	143	45	displayed	display	VBN
cord-342419-liaihahj	143	46	underneath	underneath	IN
cord-342419-liaihahj	143	47	each	each	DT
cord-342419-liaihahj	143	48	graph	graph	NN
cord-342419-liaihahj	143	49	and	and	CC
cord-342419-liaihahj	143	50	were	be	VBD
cord-342419-liaihahj	143	51	averaged	average	VBN
cord-342419-liaihahj	143	52	from	from	IN
cord-342419-liaihahj	143	53	the	the	DT
cord-342419-liaihahj	143	54	four	four	CD
cord-342419-liaihahj	143	55	replicates	replicate	NNS
cord-342419-liaihahj	143	56	.	.	.
cord-342419-liaihahj	144	1	https://doi.org/10.1371/journal.ppat.1008942.g002	https://doi.org/10.1371/journal.ppat.1008942.g002	NNP
cord-342419-liaihahj	145	1	Antibody	antibody	NN
cord-342419-liaihahj	145	2	recognition	recognition	NN
cord-342419-liaihahj	145	3	of	of	IN
cord-342419-liaihahj	145	4	the	the	DT
cord-342419-liaihahj	145	5	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	145	6	fusion	fusion	NN
cord-342419-liaihahj	145	7	protein	protein	NN
cord-342419-liaihahj	145	8	trimer	trimer	NN
cord-342419-liaihahj	145	9	interface	interface	NN
cord-342419-liaihahj	145	10	denatured	denature	VBN
cord-342419-liaihahj	145	11	hMPV	hmpv	NN
cord-342419-liaihahj	145	12	F	F	NNP
cord-342419-liaihahj	145	13	protein	protein	NN
cord-342419-liaihahj	145	14	(	(	-LRB-
cord-342419-liaihahj	145	15	S9	S9	NNP
cord-342419-liaihahj	145	16	Fig	Fig	NNP
cord-342419-liaihahj	145	17	)	)	-RRB-
cord-342419-liaihahj	145	18	.	.	.
cord-342419-liaihahj	146	1	Binding	bind	VBG
cord-342419-liaihahj	146	2	to	to	IN
cord-342419-liaihahj	146	3	hMPV	hmpv	NN
cord-342419-liaihahj	146	4	B2	b2	NN
cord-342419-liaihahj	146	5	F	F	NNP
cord-342419-liaihahj	146	6	was	be	VBD
cord-342419-liaihahj	146	7	analyzed	analyze	VBN
cord-342419-liaihahj	146	8	using	use	VBG
cord-342419-liaihahj	146	9	reduced	reduce	VBN
cord-342419-liaihahj	146	10	and	and	CC
cord-342419-liaihahj	146	11	heated	heated	JJ
cord-342419-liaihahj	146	12	protein	protein	NN
cord-342419-liaihahj	146	13	,	,	,
cord-342419-liaihahj	146	14	and	and	CC
cord-342419-liaihahj	146	15	a	a	DT
cord-342419-liaihahj	146	16	nonreduced	nonreduced	JJ
cord-342419-liaihahj	146	17	protein	protein	NN
cord-342419-liaihahj	146	18	.	.	.
cord-342419-liaihahj	147	1	MPV458	MPV458	NNP
cord-342419-liaihahj	147	2	showed	show	VBD
cord-342419-liaihahj	147	3	binding	bind	VBG
cord-342419-liaihahj	147	4	to	to	IN
cord-342419-liaihahj	147	5	all	all	DT
cord-342419-liaihahj	147	6	states	state	NNS
cord-342419-liaihahj	147	7	of	of	IN
cord-342419-liaihahj	147	8	hMPV	hmpv	NN
cord-342419-liaihahj	147	9	B2	B2	NNP
cord-342419-liaihahj	147	10	F	F	NNP
cord-342419-liaihahj	147	11	,	,	,
cord-342419-liaihahj	147	12	while	while	IN
cord-342419-liaihahj	147	13	control	control	NN
cord-342419-liaihahj	148	1	mAbs	mAbs	NNP
cord-342419-liaihahj	148	2	101F	101f	CD
cord-342419-liaihahj	148	3	and	and	CC
cord-342419-liaihahj	148	4	MPE8	MPE8	NNP
cord-342419-liaihahj	148	5	showed	show	VBD
cord-342419-liaihahj	148	6	binding	bind	VBG
cord-342419-liaihahj	148	7	to	to	IN
cord-342419-liaihahj	148	8	only	only	RB
cord-342419-liaihahj	148	9	the	the	DT
cord-342419-liaihahj	148	10	nonreduced	nonreduced	JJ
cord-342419-liaihahj	148	11	state	state	NN
cord-342419-liaihahj	148	12	.	.	.
cord-342419-liaihahj	149	1	These	these	DT
cord-342419-liaihahj	149	2	data	datum	NNS
cord-342419-liaihahj	149	3	suggest	suggest	VBP
cord-342419-liaihahj	149	4	the	the	DT
cord-342419-liaihahj	149	5	MPV458	MPV458	NNP
cord-342419-liaihahj	149	6	epitope	epitope	NN
cord-342419-liaihahj	149	7	is	be	VBZ
cord-342419-liaihahj	149	8	at	at	IN
cord-342419-liaihahj	149	9	least	least	JJS
cord-342419-liaihahj	149	10	partially	partially	RB
cord-342419-liaihahj	149	11	linear	linear	JJ
cord-342419-liaihahj	149	12	.	.	.
cord-342419-liaihahj	150	1	As	as	IN
cord-342419-liaihahj	150	2	the	the	DT
cord-342419-liaihahj	150	3	epitope	epitope	NN
cord-342419-liaihahj	150	4	for	for	IN
cord-342419-liaihahj	150	5	MPV458	MPV458	NNP
cord-342419-liaihahj	150	6	lies	lie	VBZ
cord-342419-liaihahj	150	7	within	within	IN
cord-342419-liaihahj	150	8	the	the	DT
cord-342419-liaihahj	150	9	trimer	trimer	NN
cord-342419-liaihahj	150	10	interface	interface	NN
cord-342419-liaihahj	150	11	,	,	,
cord-342419-liaihahj	150	12	the	the	DT
cord-342419-liaihahj	150	13	mechanism	mechanism	NN
cord-342419-liaihahj	150	14	by	by	IN
cord-342419-liaihahj	150	15	which	which	WDT
cord-342419-liaihahj	150	16	B	b	NN
cord-342419-liaihahj	150	17	cells	cell	NNS
cord-342419-liaihahj	150	18	recognize	recognize	VBP
cord-342419-liaihahj	150	19	this	this	DT
cord-342419-liaihahj	150	20	epitope	epitope	NN
cord-342419-liaihahj	150	21	is	be	VBZ
cord-342419-liaihahj	150	22	unclear	unclear	JJ
cord-342419-liaihahj	150	23	.	.	.
cord-342419-liaihahj	151	1	To	to	TO
cord-342419-liaihahj	151	2	determine	determine	VB
cord-342419-liaihahj	151	3	if	if	IN
cord-342419-liaihahj	151	4	the	the	DT
cord-342419-liaihahj	151	5	MPV458	MPV458	NNP
cord-342419-liaihahj	151	6	epitope	epitope	NN
cord-342419-liaihahj	151	7	is	be	VBZ
cord-342419-liaihahj	151	8	exposed	expose	VBN
cord-342419-liaihahj	151	9	on	on	IN
cord-342419-liaihahj	151	10	the	the	DT
cord-342419-liaihahj	151	11	surface	surface	NN
cord-342419-liaihahj	151	12	of	of	IN
cord-342419-liaihahj	151	13	hMPV	hmpv	NN
cord-342419-liaihahj	151	14	infected	infect	VBN
cord-342419-liaihahj	151	15	cells	cell	NNS
cord-342419-liaihahj	151	16	,	,	,
cord-342419-liaihahj	151	17	we	-PRON-	PRP
cord-342419-liaihahj	151	18	performed	perform	VBD
cord-342419-liaihahj	151	19	flow	flow	NN
cord-342419-liaihahj	151	20	cytometry	cytometry	NN
cord-342419-liaihahj	151	21	using	use	VBG
cord-342419-liaihahj	151	22	MPV458	MPV458	NNP
cord-342419-liaihahj	151	23	,	,	,
cord-342419-liaihahj	151	24	MPE8	MPE8	NNP
cord-342419-liaihahj	151	25	,	,	,
cord-342419-liaihahj	151	26	and	and	CC
cord-342419-liaihahj	151	27	a	a	DT
cord-342419-liaihahj	151	28	negative	negative	JJ
cord-342419-liaihahj	151	29	control	control	NN
cord-342419-liaihahj	151	30	pneumococcal	pneumococcal	JJ
cord-342419-liaihahj	151	31	-	-	HYPH
cord-342419-liaihahj	151	32	specific	specific	JJ
cord-342419-liaihahj	151	33	antibody	antibody	NN
cord-342419-liaihahj	151	34	(	(	-LRB-
cord-342419-liaihahj	151	35	S10	S10	NNP
cord-342419-liaihahj	151	36	Fig	Fig	NNP
cord-342419-liaihahj	151	37	)	)	-RRB-
cord-342419-liaihahj	151	38	.	.	.
cord-342419-liaihahj	152	1	Both	both	CC
cord-342419-liaihahj	152	2	MPV458	MPV458	NNP
cord-342419-liaihahj	152	3	and	and	CC
cord-342419-liaihahj	152	4	MPE8	MPE8	NNP
cord-342419-liaihahj	152	5	induced	induce	VBD
cord-342419-liaihahj	152	6	a	a	DT
cord-342419-liaihahj	152	7	fluorescent	fluorescent	JJ
cord-342419-liaihahj	152	8	shift	shift	NN
cord-342419-liaihahj	152	9	in	in	IN
cord-342419-liaihahj	152	10	hMPV	hmpv	NN
cord-342419-liaihahj	152	11	infected	infected	JJ
cord-342419-liaihahj	152	12	cells	cell	NNS
cord-342419-liaihahj	152	13	,	,	,
cord-342419-liaihahj	152	14	while	while	IN
cord-342419-liaihahj	152	15	the	the	DT
cord-342419-liaihahj	152	16	negative	negative	JJ
cord-342419-liaihahj	152	17	control	control	NN
cord-342419-liaihahj	152	18	mAb	mAb	NNPS
cord-342419-liaihahj	152	19	did	do	VBD
cord-342419-liaihahj	152	20	not	not	RB
cord-342419-liaihahj	152	21	.	.	.
cord-342419-liaihahj	153	1	This	this	DT
cord-342419-liaihahj	153	2	indicates	indicate	VBZ
cord-342419-liaihahj	153	3	the	the	DT
cord-342419-liaihahj	153	4	hMPV	hmpv	NN
cord-342419-liaihahj	153	5	F	F	NNP
cord-342419-liaihahj	153	6	protein	protein	NN
cord-342419-liaihahj	153	7	is	be	VBZ
cord-342419-liaihahj	153	8	either	either	CC
cord-342419-liaihahj	153	9	in	in	IN
cord-342419-liaihahj	153	10	 	 	_SP
cord-342419-liaihahj	153	11	Antibody	Antibody	NNP
cord-342419-liaihahj	153	12	recognition	recognition	NN
cord-342419-liaihahj	153	13	of	of	IN
cord-342419-liaihahj	153	14	the	the	DT
cord-342419-liaihahj	153	15	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	153	16	fusion	fusion	NN
cord-342419-liaihahj	153	17	protein	protein	NN
cord-342419-liaihahj	153	18	trimer	trimer	NN
cord-342419-liaihahj	153	19	interface	interface	NN
cord-342419-liaihahj	153	20	monomeric	monomeric	JJ
cord-342419-liaihahj	153	21	form	form	NN
cord-342419-liaihahj	153	22	on	on	IN
cord-342419-liaihahj	153	23	the	the	DT
cord-342419-liaihahj	153	24	surface	surface	NN
cord-342419-liaihahj	153	25	of	of	IN
cord-342419-liaihahj	153	26	infected	infected	JJ
cord-342419-liaihahj	153	27	cells	cell	NNS
cord-342419-liaihahj	153	28	,	,	,
cord-342419-liaihahj	153	29	or	or	CC
cord-342419-liaihahj	153	30	that	that	IN
cord-342419-liaihahj	153	31	hMPV	hmpv	NN
cord-342419-liaihahj	153	32	F	F	NNP
cord-342419-liaihahj	153	33	trimer	trimer	NN
cord-342419-liaihahj	153	34	exhibits	exhibit	VBZ
cord-342419-liaihahj	153	35	breathing	breathing	NN
cord-342419-liaihahj	153	36	motion	motion	NN
cord-342419-liaihahj	153	37	that	that	WDT
cord-342419-liaihahj	153	38	allows	allow	VBZ
cord-342419-liaihahj	153	39	for	for	IN
cord-342419-liaihahj	153	40	binding	bind	VBG
cord-342419-liaihahj	153	41	of	of	IN
cord-342419-liaihahj	153	42	MPV458	MPV458	NNP
cord-342419-liaihahj	153	43	.	.	.
cord-342419-liaihahj	154	1	By	by	IN
cord-342419-liaihahj	154	2	comparing	compare	VBG
cord-342419-liaihahj	154	3	the	the	DT
cord-342419-liaihahj	154	4	binding	bind	VBG
cord-342419-liaihahj	154	5	sites	site	NNS
cord-342419-liaihahj	154	6	with	with	IN
cord-342419-liaihahj	154	7	previously	previously	RB
cord-342419-liaihahj	154	8	The	the	DT
cord-342419-liaihahj	154	9	corresponding	corresponding	JJ
cord-342419-liaihahj	154	10	66	66	CD
cord-342419-liaihahj	154	11	-	-	SYM
cord-342419-liaihahj	154	12	87	87	CD
cord-342419-liaihahj	154	13	epitope	epitope	NN
cord-342419-liaihahj	154	14	is	be	VBZ
cord-342419-liaihahj	154	15	colored	color	VBN
cord-342419-liaihahj	154	16	on	on	IN
cord-342419-liaihahj	154	17	the	the	DT
cord-342419-liaihahj	154	18	X	x	NN
cord-342419-liaihahj	154	19	-	-	NN
cord-342419-liaihahj	154	20	ray	ray	NN
cord-342419-liaihahj	154	21	crystal	crystal	NN
cord-342419-liaihahj	154	22	structure	structure	NN
cord-342419-liaihahj	154	23	of	of	IN
cord-342419-liaihahj	154	24	post	post	JJ
cord-342419-liaihahj	154	25	-	-	JJ
cord-342419-liaihahj	154	26	fusion	fusion	JJ
cord-342419-liaihahj	154	27	hMPV	hmpv	NN
cord-342419-liaihahj	154	28	F	F	NNP
cord-342419-liaihahj	154	29	(	(	-LRB-
cord-342419-liaihahj	154	30	5L1X	5l1x	CD
cord-342419-liaihahj	154	31	)	)	-RRB-
cord-342419-liaihahj	154	32	.	.	.
cord-342419-liaihahj	155	1	The	the	DT
cord-342419-liaihahj	155	2	66	66	CD
cord-342419-liaihahj	155	3	-	-	SYM
cord-342419-liaihahj	155	4	87	87	CD
cord-342419-liaihahj	155	5	epitope	epitope	NN
cord-342419-liaihahj	155	6	is	be	VBZ
cord-342419-liaihahj	155	7	surface	surface	NN
cord-342419-liaihahj	155	8	exposed	expose	VBN
cord-342419-liaihahj	155	9	on	on	IN
cord-342419-liaihahj	155	10	trimeric	trimeric	JJ
cord-342419-liaihahj	155	11	post	post	JJ
cord-342419-liaihahj	155	12	-	-	JJ
cord-342419-liaihahj	155	13	fusion	fusion	JJ
cord-342419-liaihahj	156	1	hMPV	hMPV	NNP
cord-342419-liaihahj	156	2	F.	F.	NNP
cord-342419-liaihahj	156	3	(	(	-LRB-
cord-342419-liaihahj	156	4	C	C	NNP
cord-342419-liaihahj	156	5	)	)	-RRB-
cord-342419-liaihahj	156	6	Structural	structural	JJ
cord-342419-liaihahj	156	7	overlay	overlay	NN
cord-342419-liaihahj	156	8	of	of	IN
cord-342419-liaihahj	156	9	the	the	DT
cord-342419-liaihahj	156	10	66	66	CD
cord-342419-liaihahj	156	11	-	-	SYM
cord-342419-liaihahj	156	12	87	87	CD
cord-342419-liaihahj	156	13	region	region	NN
cord-342419-liaihahj	156	14	between	between	IN
cord-342419-liaihahj	156	15	pre	pre	JJ
cord-342419-liaihahj	156	16	-	-	JJ
cord-342419-liaihahj	156	17	fusion	fusion	JJ
cord-342419-liaihahj	156	18	(	(	-LRB-
cord-342419-liaihahj	156	19	cyan	cyan	NNP
cord-342419-liaihahj	156	20	)	)	-RRB-
cord-342419-liaihahj	156	21	hMPV	hmpv	NN
cord-342419-liaihahj	156	22	F	F	NNP
cord-342419-liaihahj	156	23	from	from	IN
cord-342419-liaihahj	156	24	the	the	DT
cord-342419-liaihahj	156	25	hMPV	hmpv	NN
cord-342419-liaihahj	156	26	B2	b2	NN
cord-342419-liaihahj	156	27	F	F	NNP
cord-342419-liaihahj	156	28	+	+	CC
cord-342419-liaihahj	156	29	MPV458	MPV458	NNP
cord-342419-liaihahj	157	1	Fab	fab	JJ
cord-342419-liaihahj	157	2	complex	complex	NN
cord-342419-liaihahj	157	3	and	and	CC
cord-342419-liaihahj	157	4	post	post	JJ
cord-342419-liaihahj	157	5	-	-	JJ
cord-342419-liaihahj	157	6	fusion	fusion	JJ
cord-342419-liaihahj	157	7	(	(	-LRB-
cord-342419-liaihahj	157	8	red	red	NN
cord-342419-liaihahj	157	9	)	)	-RRB-
cord-342419-liaihahj	158	1	hMPV	hMPV	NNP
cord-342419-liaihahj	158	2	F	F	NNP
cord-342419-liaihahj	158	3	(	(	-LRB-
cord-342419-liaihahj	158	4	PDB	PDB	NNP
cord-342419-liaihahj	158	5	ID	ID	NNP
cord-342419-liaihahj	158	6	:	:	:
cord-342419-liaihahj	158	7	5L1X	5l1x	CD
cord-342419-liaihahj	158	8	)	)	-RRB-
cord-342419-liaihahj	158	9	.	.	.
cord-342419-liaihahj	159	1	Conserved	conserved	JJ
cord-342419-liaihahj	159	2	amino	amino	NN
cord-342419-liaihahj	159	3	acid	acid	NN
cord-342419-liaihahj	159	4	residues	residue	NNS
cord-342419-liaihahj	159	5	between	between	IN
cord-342419-liaihahj	159	6	the	the	DT
cord-342419-liaihahj	159	7	B2	b2	NN
cord-342419-liaihahj	159	8	and	and	CC
cord-342419-liaihahj	159	9	A1	A1	NNP
cord-342419-liaihahj	159	10	subgroups	subgroup	NNS
cord-342419-liaihahj	159	11	are	be	VBP
cord-342419-liaihahj	159	12	listed	list	VBN
cord-342419-liaihahj	159	13	in	in	IN
cord-342419-liaihahj	159	14	black	black	JJ
cord-342419-liaihahj	159	15	,	,	,
cord-342419-liaihahj	159	16	while	while	IN
cord-342419-liaihahj	159	17	residues	residue	NNS
cord-342419-liaihahj	159	18	that	that	WDT
cord-342419-liaihahj	159	19	have	have	VBP
cord-342419-liaihahj	159	20	mutations	mutation	NNS
cord-342419-liaihahj	159	21	or	or	CC
cord-342419-liaihahj	159	22	shift	shift	NN
cord-342419-liaihahj	159	23	positions	position	NNS
cord-342419-liaihahj	159	24	are	be	VBP
cord-342419-liaihahj	159	25	colored	color	VBN
cord-342419-liaihahj	159	26	according	accord	VBG
cord-342419-liaihahj	159	27	to	to	IN
cord-342419-liaihahj	159	28	the	the	DT
cord-342419-liaihahj	159	29	corresponding	corresponding	JJ
cord-342419-liaihahj	159	30	structure	structure	NN
cord-342419-liaihahj	159	31	.	.	.
cord-342419-liaihahj	160	1	(	(	-LRB-
cord-342419-liaihahj	160	2	D	D	NNP
cord-342419-liaihahj	160	3	)	)	-RRB-
cord-342419-liaihahj	160	4	Structural	structural	JJ
cord-342419-liaihahj	160	5	overlay	overlay	NN
cord-342419-liaihahj	160	6	of	of	IN
cord-342419-liaihahj	160	7	MPV458	MPV458	NNP
cord-342419-liaihahj	160	8	on	on	IN
cord-342419-liaihahj	160	9	the	the	DT
cord-342419-liaihahj	160	10	hMPV	hmpv	NN
cord-342419-liaihahj	160	11	F	F	NNP
cord-342419-liaihahj	160	12	protein	protein	NN
cord-342419-liaihahj	160	13	with	with	IN
cord-342419-liaihahj	160	14	previously	previously	RB
cord-342419-liaihahj	160	15	structurally	structurally	RB
cord-342419-liaihahj	160	16	characterized	characterize	VBN
cord-342419-liaihahj	160	17	hMPV	hmpv	NN
cord-342419-liaihahj	160	18	F	F	NNP
cord-342419-liaihahj	160	19	-	-	HYPH
cord-342419-liaihahj	160	20	specific	specific	JJ
cord-342419-liaihahj	160	21	mAbs	mAbs	NNP
cord-342419-liaihahj	160	22	.	.	.
cord-342419-liaihahj	161	1	MPE8	MPE8	NNP
cord-342419-liaihahj	161	2	(	(	-LRB-
cord-342419-liaihahj	161	3	site	site	NN
cord-342419-liaihahj	161	4	III	iii	CD
cord-342419-liaihahj	161	5	,	,	,
cord-342419-liaihahj	161	6	orange	orange	NNP
cord-342419-liaihahj	161	7	)	)	-RRB-
cord-342419-liaihahj	161	8	and	and	CC
cord-342419-liaihahj	161	9	101F	101f	CD
cord-342419-liaihahj	162	1	(	(	-LRB-
cord-342419-liaihahj	162	2	site	site	NN
cord-342419-liaihahj	162	3	IV	IV	NNP
cord-342419-liaihahj	162	4	,	,	,
cord-342419-liaihahj	162	5	red	red	NN
cord-342419-liaihahj	162	6	)	)	-RRB-
cord-342419-liaihahj	162	7	were	be	VBD
cord-342419-liaihahj	162	8	aligned	align	VBN
cord-342419-liaihahj	162	9	onto	onto	IN
cord-342419-liaihahj	162	10	hMPV	hmpv	NN
cord-342419-liaihahj	162	11	F	F	NNP
cord-342419-liaihahj	162	12	by	by	IN
cord-342419-liaihahj	162	13	aligning	align	VBG
cord-342419-liaihahj	162	14	the	the	DT
cord-342419-liaihahj	162	15	corresponding	correspond	VBG
cord-342419-liaihahj	162	16	RSV	RSV	NNP
cord-342419-liaihahj	162	17	F	F	NNP
cord-342419-liaihahj	162	18	residues	residue	NNS
cord-342419-liaihahj	162	19	onto	onto	IN
cord-342419-liaihahj	162	20	hMPV	hmpv	NN
cord-342419-liaihahj	162	21	F	F	NNP
cord-342419-liaihahj	162	22	from	from	IN
cord-342419-liaihahj	162	23	the	the	DT
cord-342419-liaihahj	162	24	co	co	JJ
cord-342419-liaihahj	162	25	-	-	JJ
cord-342419-liaihahj	162	26	complex	complex	JJ
cord-342419-liaihahj	162	27	structures	structure	NNS
cord-342419-liaihahj	162	28	with	with	IN
cord-342419-liaihahj	162	29	RSV	RSV	NNP
cord-342419-liaihahj	162	30	F	F	NNP
cord-342419-liaihahj	162	31	(	(	-LRB-
cord-342419-liaihahj	162	32	PDB	PDB	NNP
cord-342419-liaihahj	162	33	ID	ID	NNP
cord-342419-liaihahj	162	34	:	:	:
cord-342419-liaihahj	163	1	5U68	5u68	CD
cord-342419-liaihahj	163	2	and	and	CC
cord-342419-liaihahj	163	3	PBD	PBD	NNP
cord-342419-liaihahj	163	4	ID	ID	NNP
cord-342419-liaihahj	163	5	:	:	:
cord-342419-liaihahj	163	6	3O45	3o45	CD
cord-342419-liaihahj	163	7	)	)	-RRB-
cord-342419-liaihahj	163	8	.	.	.
cord-342419-liaihahj	164	1	DS7	DS7	NNP
cord-342419-liaihahj	164	2	was	be	VBD
cord-342419-liaihahj	164	3	aligned	align	VBN
cord-342419-liaihahj	164	4	from	from	IN
cord-342419-liaihahj	164	5	PDB	PDB	NNP
cord-342419-liaihahj	164	6	4DAG	4dag	CD
cord-342419-liaihahj	164	7	.	.	.
cord-342419-liaihahj	165	1	(	(	-LRB-
cord-342419-liaihahj	165	2	E	e	NN
cord-342419-liaihahj	165	3	)	)	-RRB-
cord-342419-liaihahj	166	1	The	the	DT
cord-342419-liaihahj	166	2	structure	structure	NN
cord-342419-liaihahj	166	3	overlay	overlay	NN
cord-342419-liaihahj	166	4	in	in	IN
cord-342419-liaihahj	166	5	(	(	-LRB-
cord-342419-liaihahj	166	6	D	D	NNP
cord-342419-liaihahj	166	7	)	)	-RRB-
cord-342419-liaihahj	166	8	is	be	VBZ
cord-342419-liaihahj	166	9	rotated	rotate	VBN
cord-342419-liaihahj	166	10	90	90	CD
cord-342419-liaihahj	166	11	degrees	degree	NNS
cord-342419-liaihahj	166	12	to	to	TO
cord-342419-liaihahj	166	13	view	view	VB
cord-342419-liaihahj	166	14	the	the	DT
cord-342419-liaihahj	166	15	hMPV	hmpv	NN
cord-342419-liaihahj	166	16	F	F	NNP
cord-342419-liaihahj	166	17	protein	protein	NN
cord-342419-liaihahj	166	18	from	from	IN
cord-342419-liaihahj	166	19	the	the	DT
cord-342419-liaihahj	166	20	top	top	NN
cord-342419-liaihahj	166	21	down	down	RB
cord-342419-liaihahj	166	22	.	.	.
cord-342419-liaihahj	166	23	 	 	_SP
cord-342419-liaihahj	167	1	Antibody	antibody	NN
cord-342419-liaihahj	167	2	recognition	recognition	NN
cord-342419-liaihahj	167	3	of	of	IN
cord-342419-liaihahj	167	4	the	the	DT
cord-342419-liaihahj	167	5	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	167	6	fusion	fusion	NN
cord-342419-liaihahj	167	7	protein	protein	NN
cord-342419-liaihahj	167	8	trimer	trimer	NN
cord-342419-liaihahj	167	9	interface	interface	NN
cord-342419-liaihahj	167	10	described	describe	VBD
cord-342419-liaihahj	167	11	hMPV	hmpv	NN
cord-342419-liaihahj	167	12	F	F	NNP
cord-342419-liaihahj	167	13	-	-	HYPH
cord-342419-liaihahj	167	14	specific	specific	JJ
cord-342419-liaihahj	167	15	mAbs	mabs	NN
cord-342419-liaihahj	167	16	that	that	WDT
cord-342419-liaihahj	167	17	have	have	VBP
cord-342419-liaihahj	167	18	been	be	VBN
cord-342419-liaihahj	167	19	structurally	structurally	RB
cord-342419-liaihahj	167	20	characterized	characterize	VBN
cord-342419-liaihahj	167	21	(	(	-LRB-
cord-342419-liaihahj	167	22	MPE8	MPE8	NNP
cord-342419-liaihahj	167	23	,	,	,
cord-342419-liaihahj	167	24	101F	101f	CD
cord-342419-liaihahj	167	25	,	,	,
cord-342419-liaihahj	167	26	and	and	CC
cord-342419-liaihahj	167	27	DS7	DS7	NNP
cord-342419-liaihahj	167	28	)	)	-RRB-
cord-342419-liaihahj	167	29	,	,	,
cord-342419-liaihahj	167	30	the	the	DT
cord-342419-liaihahj	167	31	MPV458	MPV458	NNP
cord-342419-liaihahj	167	32	epitope	epitope	NN
cord-342419-liaihahj	167	33	is	be	VBZ
cord-342419-liaihahj	167	34	distant	distant	JJ
cord-342419-liaihahj	167	35	from	from	IN
cord-342419-liaihahj	167	36	all	all	DT
cord-342419-liaihahj	167	37	three	three	CD
cord-342419-liaihahj	167	38	known	know	VBN
cord-342419-liaihahj	167	39	antigenic	antigenic	JJ
cord-342419-liaihahj	167	40	sites	site	NNS
cord-342419-liaihahj	167	41	(	(	-LRB-
cord-342419-liaihahj	167	42	IV	IV	NNP
cord-342419-liaihahj	167	43	,	,	,
cord-342419-liaihahj	167	44	DS7-site	DS7-site	NNP
cord-342419-liaihahj	167	45	,	,	,
cord-342419-liaihahj	167	46	and	and	CC
cord-342419-liaihahj	167	47	III	III	NNP
cord-342419-liaihahj	167	48	)	)	-RRB-
cord-342419-liaihahj	167	49	,	,	,
cord-342419-liaihahj	167	50	and	and	CC
cord-342419-liaihahj	167	51	lies	lie	NNS
cord-342419-liaihahj	167	52	on	on	IN
cord-342419-liaihahj	167	53	the	the	DT
cord-342419-liaihahj	167	54	opposite	opposite	JJ
cord-342419-liaihahj	167	55	face	face	NN
cord-342419-liaihahj	167	56	of	of	IN
cord-342419-liaihahj	167	57	the	the	DT
cord-342419-liaihahj	167	58	monomeric	monomeric	JJ
cord-342419-liaihahj	167	59	hMPV	hmpv	NN
cord-342419-liaihahj	167	60	F	F	NNP
cord-342419-liaihahj	167	61	protein	protein	NN
cord-342419-liaihahj	167	62	(	(	-LRB-
cord-342419-liaihahj	167	63	Fig	Fig	NNP
cord-342419-liaihahj	167	64	4D	4d	CD
cord-342419-liaihahj	167	65	;	;	:
cord-342419-liaihahj	167	66	Fig	Fig	NNP
cord-342419-liaihahj	167	67	4E	4e	CD
cord-342419-liaihahj	167	68	)	)	-RRB-
cord-342419-liaihahj	167	69	.	.	.
cord-342419-liaihahj	168	1	This	this	DT
cord-342419-liaihahj	168	2	unique	unique	JJ
cord-342419-liaihahj	168	3	epitope	epitope	NN
cord-342419-liaihahj	168	4	was	be	VBD
cord-342419-liaihahj	168	5	unexpected	unexpected	JJ
cord-342419-liaihahj	168	6	on	on	IN
cord-342419-liaihahj	168	7	the	the	DT
cord-342419-liaihahj	168	8	hMPV	hmpv	NN
cord-342419-liaihahj	168	9	F	F	NNP
cord-342419-liaihahj	168	10	protein	protein	NN
cord-342419-liaihahj	168	11	,	,	,
cord-342419-liaihahj	168	12	although	although	IN
cord-342419-liaihahj	168	13	intratrimeric	intratrimeric	NNP
cord-342419-liaihahj	168	14	epitopes	epitope	NNS
cord-342419-liaihahj	168	15	have	have	VBP
cord-342419-liaihahj	168	16	been	be	VBN
cord-342419-liaihahj	168	17	observed	observe	VBN
cord-342419-liaihahj	168	18	on	on	IN
cord-342419-liaihahj	168	19	the	the	DT
cord-342419-liaihahj	168	20	influenza	influenza	NN
cord-342419-liaihahj	168	21	hemagglutinin	hemagglutinin	NN
cord-342419-liaihahj	168	22	protein	protein	NN
cord-342419-liaihahj	168	23	[	[	-LRB-
cord-342419-liaihahj	168	24	60	60	CD
cord-342419-liaihahj	168	25	]	]	-RRB-
cord-342419-liaihahj	168	26	[	[	-LRB-
cord-342419-liaihahj	168	27	61	61	CD
cord-342419-liaihahj	168	28	]	]	-RRB-
cord-342419-liaihahj	168	29	[	[	-LRB-
cord-342419-liaihahj	168	30	62	62	CD
cord-342419-liaihahj	168	31	]	]	-RRB-
cord-342419-liaihahj	168	32	[	[	-LRB-
cord-342419-liaihahj	168	33	63	63	CD
cord-342419-liaihahj	168	34	]	]	-RRB-
cord-342419-liaihahj	168	35	[	[	-LRB-
cord-342419-liaihahj	168	36	64	64	CD
cord-342419-liaihahj	168	37	]	]	-RRB-
cord-342419-liaihahj	168	38	.	.	.
cord-342419-liaihahj	169	1	However	however	RB
cord-342419-liaihahj	169	2	,	,	,
cord-342419-liaihahj	169	3	these	these	DT
cord-342419-liaihahj	169	4	previously	previously	RB
cord-342419-liaihahj	169	5	discovered	discover	VBN
cord-342419-liaihahj	169	6	influenza	influenza	NN
cord-342419-liaihahj	169	7	-	-	HYPH
cord-342419-liaihahj	169	8	specific	specific	JJ
cord-342419-liaihahj	169	9	mAbs	mAbs	NNP
cord-342419-liaihahj	169	10	have	have	VBP
cord-342419-liaihahj	169	11	been	be	VBN
cord-342419-liaihahj	169	12	nonneutralizing	nonneutralize	VBG
cord-342419-liaihahj	169	13	,	,	,
cord-342419-liaihahj	169	14	and	and	CC
cord-342419-liaihahj	169	15	a	a	DT
cord-342419-liaihahj	169	16	subset	subset	NN
cord-342419-liaihahj	169	17	were	be	VBD
cord-342419-liaihahj	169	18	determined	determine	VBN
cord-342419-liaihahj	169	19	to	to	TO
cord-342419-liaihahj	169	20	function	function	VB
cord-342419-liaihahj	169	21	by	by	IN
cord-342419-liaihahj	169	22	disrupting	disrupt	VBG
cord-342419-liaihahj	169	23	the	the	DT
cord-342419-liaihahj	169	24	HA	HA	NNP
cord-342419-liaihahj	169	25	trimer	trimer	NN
cord-342419-liaihahj	169	26	and	and	CC
cord-342419-liaihahj	169	27	inhibiting	inhibit	VBG
cord-342419-liaihahj	169	28	cell	cell	NN
cord-342419-liaihahj	169	29	-	-	HYPH
cord-342419-liaihahj	169	30	to	to	IN
cord-342419-liaihahj	169	31	-	-	HYPH
cord-342419-liaihahj	169	32	cell	cell	NN
cord-342419-liaihahj	169	33	spread	spread	NN
cord-342419-liaihahj	169	34	[	[	-LRB-
cord-342419-liaihahj	169	35	60	60	CD
cord-342419-liaihahj	169	36	,	,	,
cord-342419-liaihahj	169	37	64	64	CD
cord-342419-liaihahj	169	38	]	]	-RRB-
cord-342419-liaihahj	169	39	.	.	.
cord-342419-liaihahj	170	1	Evidence	evidence	NN
cord-342419-liaihahj	170	2	for	for	IN
cord-342419-liaihahj	170	3	pneumovirus	pneumovirus	NNP
cord-342419-liaihahj	170	4	F	F	NNP
cord-342419-liaihahj	170	5	protein	protein	NN
cord-342419-liaihahj	170	6	breathing	breathing	NN
cord-342419-liaihahj	170	7	was	be	VBD
cord-342419-liaihahj	170	8	previously	previously	RB
cord-342419-liaihahj	170	9	demonstrated	demonstrate	VBN
cord-342419-liaihahj	170	10	for	for	IN
cord-342419-liaihahj	170	11	the	the	DT
cord-342419-liaihahj	170	12	RSV	RSV	NNP
cord-342419-liaihahj	170	13	F	F	NNP
cord-342419-liaihahj	170	14	protein	protein	NN
cord-342419-liaihahj	170	15	,	,	,
cord-342419-liaihahj	170	16	whereby	whereby	WRB
cord-342419-liaihahj	170	17	the	the	DT
cord-342419-liaihahj	170	18	mAb	mAb	NNP
cord-342419-liaihahj	170	19	CR9501	CR9501	NNP
cord-342419-liaihahj	170	20	that	that	WDT
cord-342419-liaihahj	170	21	binds	bind	VBZ
cord-342419-liaihahj	170	22	at	at	IN
cord-342419-liaihahj	170	23	antigenic	antigenic	JJ
cord-342419-liaihahj	170	24	site	site	NN
cord-342419-liaihahj	170	25	V	v	NN
cord-342419-liaihahj	170	26	enhances	enhance	VBZ
cord-342419-liaihahj	170	27	opening	opening	NN
cord-342419-liaihahj	170	28	of	of	IN
cord-342419-liaihahj	170	29	the	the	DT
cord-342419-liaihahj	170	30	pre	pre	JJ
cord-342419-liaihahj	170	31	-	-	JJ
cord-342419-liaihahj	170	32	fusion	fusion	JJ
cord-342419-liaihahj	170	33	RSV	RSV	NNP
cord-342419-liaihahj	170	34	F	F	NNP
cord-342419-liaihahj	170	35	protein	protein	NN
cord-342419-liaihahj	170	36	[	[	-LRB-
cord-342419-liaihahj	170	37	65	65	CD
cord-342419-liaihahj	170	38	]	]	-RRB-
cord-342419-liaihahj	170	39	,	,	,
cord-342419-liaihahj	170	40	suggesting	suggest	VBG
cord-342419-liaihahj	170	41	a	a	DT
cord-342419-liaihahj	170	42	similar	similar	JJ
cord-342419-liaihahj	170	43	process	process	NN
cord-342419-liaihahj	170	44	may	may	MD
cord-342419-liaihahj	170	45	occur	occur	VB
cord-342419-liaihahj	170	46	for	for	IN
cord-342419-liaihahj	171	1	hMPV	hMPV	NNP
cord-342419-liaihahj	171	2	F.	F.	NNP
cord-342419-liaihahj	171	3	Here	here	RB
cord-342419-liaihahj	171	4	we	-PRON-	PRP
cord-342419-liaihahj	171	5	demonstrate	demonstrate	VBP
cord-342419-liaihahj	171	6	a	a	DT
cord-342419-liaihahj	171	7	new	new	JJ
cord-342419-liaihahj	171	8	class	class	NN
cord-342419-liaihahj	171	9	of	of	IN
cord-342419-liaihahj	171	10	neutralizing	neutralize	VBG
cord-342419-liaihahj	171	11	hMPV	hmpv	NN
cord-342419-liaihahj	171	12	F	F	NNP
cord-342419-liaihahj	171	13	-	-	HYPH
cord-342419-liaihahj	171	14	specific	specific	JJ
cord-342419-liaihahj	171	15	human	human	JJ
cord-342419-liaihahj	171	16	mAbs	mabs	NN
cord-342419-liaihahj	171	17	.	.	.
cord-342419-liaihahj	172	1	The	the	DT
cord-342419-liaihahj	172	2	mAbs	mabs	NN
cord-342419-liaihahj	172	3	are	be	VBP
cord-342419-liaihahj	172	4	broadly	broadly	RB
cord-342419-liaihahj	172	5	reactive	reactive	JJ
cord-342419-liaihahj	172	6	across	across	IN
cord-342419-liaihahj	172	7	all	all	DT
cord-342419-liaihahj	172	8	hMPV	hmpv	NN
cord-342419-liaihahj	172	9	subgroups	subgroup	NNS
cord-342419-liaihahj	172	10	,	,	,
cord-342419-liaihahj	172	11	and	and	CC
cord-342419-liaihahj	172	12	neutralize	neutralize	VB
cord-342419-liaihahj	172	13	viruses	virus	NNS
cord-342419-liaihahj	172	14	from	from	IN
cord-342419-liaihahj	172	15	both	both	CC
cord-342419-liaihahj	172	16	hMPV	hmpv	NN
cord-342419-liaihahj	172	17	genotypes	genotype	NNS
cord-342419-liaihahj	172	18	.	.	.
cord-342419-liaihahj	173	1	The	the	DT
cord-342419-liaihahj	173	2	mAbs	mabs	NN
cord-342419-liaihahj	173	3	were	be	VBD
cord-342419-liaihahj	173	4	discovered	discover	VBN
cord-342419-liaihahj	173	5	to	to	TO
cord-342419-liaihahj	173	6	bind	bind	VB
cord-342419-liaihahj	173	7	to	to	IN
cord-342419-liaihahj	173	8	a	a	DT
cord-342419-liaihahj	173	9	novel	novel	JJ
cord-342419-liaihahj	173	10	epitope	epitope	NN
cord-342419-liaihahj	173	11	by	by	IN
cord-342419-liaihahj	173	12	competition	competition	NN
cord-342419-liaihahj	173	13	experiments	experiment	NNS
cord-342419-liaihahj	173	14	with	with	IN
cord-342419-liaihahj	173	15	previously	previously	RB
cord-342419-liaihahj	173	16	discovered	discover	VBN
cord-342419-liaihahj	173	17	rodent	rodent	NN
cord-342419-liaihahj	173	18	and	and	CC
cord-342419-liaihahj	173	19	human	human	NN
cord-342419-liaihahj	173	20	derived	derive	VBN
cord-342419-liaihahj	173	21	hMPV	hmpv	NN
cord-342419-liaihahj	173	22	F	F	NNP
cord-342419-liaihahj	173	23	-	-	HYPH
cord-342419-liaihahj	173	24	specific	specific	JJ
cord-342419-liaihahj	173	25	mAbs	mAbs	NNP
cord-342419-liaihahj	173	26	.	.	.
cord-342419-liaihahj	174	1	The	the	DT
cord-342419-liaihahj	174	2	RSV	RSV	NNP
cord-342419-liaihahj	174	3	F	F	NNP
cord-342419-liaihahj	174	4	protein	protein	NN
cord-342419-liaihahj	174	5	has	have	VBZ
cord-342419-liaihahj	174	6	at	at	RB
cord-342419-liaihahj	174	7	least	least	RBS
cord-342419-liaihahj	174	8	two	two	CD
cord-342419-liaihahj	174	9	antigenic	antigenic	JJ
cord-342419-liaihahj	174	10	sites	site	NNS
cord-342419-liaihahj	174	11	that	that	WDT
cord-342419-liaihahj	174	12	are	be	VBP
cord-342419-liaihahj	174	13	surface	surface	NN
cord-342419-liaihahj	174	14	exposed	expose	VBN
cord-342419-liaihahj	174	15	on	on	IN
cord-342419-liaihahj	174	16	the	the	DT
cord-342419-liaihahj	174	17	head	head	NN
cord-342419-liaihahj	174	18	of	of	IN
cord-342419-liaihahj	174	19	the	the	DT
cord-342419-liaihahj	174	20	trimeric	trimeric	JJ
cord-342419-liaihahj	174	21	surface	surface	NN
cord-342419-liaihahj	174	22	(	(	-LRB-
cord-342419-liaihahj	174	23	antigenic	antigenic	JJ
cord-342419-liaihahj	174	24	sites	site	NNS
cord-342419-liaihahj	174	25	Ø	ø	NN
cord-342419-liaihahj	174	26	[	[	-LRB-
cord-342419-liaihahj	174	27	66	66	CD
cord-342419-liaihahj	174	28	]	]	-RRB-
cord-342419-liaihahj	174	29	and	and	CC
cord-342419-liaihahj	174	30	V	V	NNP
cord-342419-liaihahj	174	31	[	[	-LRB-
cord-342419-liaihahj	174	32	44	44	CD
cord-342419-liaihahj	174	33	,	,	,
cord-342419-liaihahj	174	34	45	45	CD
cord-342419-liaihahj	174	35	]	]	-RRB-
cord-342419-liaihahj	174	36	)	)	-RRB-
cord-342419-liaihahj	174	37	,	,	,
cord-342419-liaihahj	174	38	however	however	RB
cord-342419-liaihahj	174	39	,	,	,
cord-342419-liaihahj	174	40	such	such	JJ
cord-342419-liaihahj	174	41	antigenic	antigenic	JJ
cord-342419-liaihahj	174	42	sites	site	NNS
cord-342419-liaihahj	174	43	have	have	VBP
cord-342419-liaihahj	174	44	not	not	RB
cord-342419-liaihahj	174	45	yet	yet	RB
cord-342419-liaihahj	174	46	been	be	VBN
cord-342419-liaihahj	174	47	identified	identify	VBN
cord-342419-liaihahj	174	48	for	for	IN
cord-342419-liaihahj	174	49	hMPV	hmpv	NN
cord-342419-liaihahj	174	50	F	F	NNP
cord-342419-liaihahj	174	51	,	,	,
cord-342419-liaihahj	174	52	likely	likely	RB
cord-342419-liaihahj	174	53	due	due	IN
cord-342419-liaihahj	174	54	to	to	IN
cord-342419-liaihahj	174	55	glycan	glycan	NN
cord-342419-liaihahj	174	56	shielding	shielding	NN
cord-342419-liaihahj	174	57	[	[	-LRB-
cord-342419-liaihahj	174	58	38	38	CD
cord-342419-liaihahj	174	59	]	]	-RRB-
cord-342419-liaihahj	174	60	.	.	.
cord-342419-liaihahj	175	1	Furthermore	furthermore	RB
cord-342419-liaihahj	175	2	,	,	,
cord-342419-liaihahj	175	3	the	the	DT
cord-342419-liaihahj	175	4	X	x	NN
cord-342419-liaihahj	175	5	-	-	NN
cord-342419-liaihahj	175	6	ray	ray	NN
cord-342419-liaihahj	175	7	crystal	crystal	NN
cord-342419-liaihahj	175	8	structure	structure	NN
cord-342419-liaihahj	175	9	of	of	IN
cord-342419-liaihahj	175	10	one	one	CD
cord-342419-liaihahj	175	11	mAb	mAb	NNS
cord-342419-liaihahj	175	12	,	,	,
cord-342419-liaihahj	175	13	MPV458	MPV458	NNP
cord-342419-liaihahj	175	14	,	,	,
cord-342419-liaihahj	175	15	was	be	VBD
cord-342419-liaihahj	175	16	determined	determine	VBN
cord-342419-liaihahj	175	17	in	in	IN
cord-342419-liaihahj	175	18	complex	complex	NN
cord-342419-liaihahj	175	19	with	with	IN
cord-342419-liaihahj	175	20	the	the	DT
cord-342419-liaihahj	175	21	hMPV	hmpv	NN
cord-342419-liaihahj	175	22	F	F	NNP
cord-342419-liaihahj	175	23	protein	protein	NN
cord-342419-liaihahj	175	24	and	and	CC
cord-342419-liaihahj	175	25	solved	solve	VBD
cord-342419-liaihahj	175	26	to	to	IN
cord-342419-liaihahj	175	27	3.1	3.1	CD
cord-342419-liaihahj	175	28	Å.	å.	NN
cord-342419-liaihahj	176	1	The	the	DT
cord-342419-liaihahj	176	2	structure	structure	NN
cord-342419-liaihahj	176	3	revealed	reveal	VBD
cord-342419-liaihahj	176	4	MPV458	MPV458	NNP
cord-342419-liaihahj	176	5	binds	bind	VBZ
cord-342419-liaihahj	176	6	at	at	IN
cord-342419-liaihahj	176	7	a	a	DT
cord-342419-liaihahj	176	8	newly	newly	RB
cord-342419-liaihahj	176	9	defined	define	VBN
cord-342419-liaihahj	176	10	epitope	epitope	NN
cord-342419-liaihahj	176	11	on	on	IN
cord-342419-liaihahj	176	12	the	the	DT
cord-342419-liaihahj	176	13	hMPV	hmpv	NN
cord-342419-liaihahj	176	14	F	F	NNP
cord-342419-liaihahj	176	15	protein	protein	NN
cord-342419-liaihahj	176	16	defined	define	VBN
cord-342419-liaihahj	176	17	by	by	IN
cord-342419-liaihahj	176	18	the	the	DT
cord-342419-liaihahj	176	19	alpha	alpha	NN
cord-342419-liaihahj	176	20	helical	helical	JJ
cord-342419-liaihahj	176	21	66	66	CD
cord-342419-liaihahj	176	22	-	-	SYM
cord-342419-liaihahj	176	23	87	87	CD
cord-342419-liaihahj	176	24	amino	amino	NN
cord-342419-liaihahj	176	25	acid	acid	NN
cord-342419-liaihahj	176	26	region	region	NN
cord-342419-liaihahj	176	27	contained	contain	VBN
cord-342419-liaihahj	176	28	within	within	IN
cord-342419-liaihahj	176	29	the	the	DT
cord-342419-liaihahj	176	30	F2	F2	NNP
cord-342419-liaihahj	176	31	fragment	fragment	NN
cord-342419-liaihahj	176	32	on	on	IN
cord-342419-liaihahj	176	33	pre	pre	JJ
cord-342419-liaihahj	176	34	-	-	JJ
cord-342419-liaihahj	176	35	fusion	fusion	JJ
cord-342419-liaihahj	176	36	hMPV	hmpv	NN
cord-342419-liaihahj	176	37	F.	F.	NNP
cord-342419-liaihahj	176	38	This	this	DT
cord-342419-liaihahj	176	39	new	new	JJ
cord-342419-liaihahj	176	40	epitope	epitope	NN
cord-342419-liaihahj	176	41	is	be	VBZ
cord-342419-liaihahj	176	42	the	the	DT
cord-342419-liaihahj	176	43	first	first	JJ
cord-342419-liaihahj	176	44	defined	define	VBN
cord-342419-liaihahj	176	45	on	on	IN
cord-342419-liaihahj	176	46	the	the	DT
cord-342419-liaihahj	176	47	head	head	NN
cord-342419-liaihahj	176	48	of	of	IN
cord-342419-liaihahj	176	49	the	the	DT
cord-342419-liaihahj	176	50	hMPV	hmpv	NN
cord-342419-liaihahj	176	51	F	F	NNP
cord-342419-liaihahj	176	52	protein	protein	NN
cord-342419-liaihahj	176	53	as	as	IN
cord-342419-liaihahj	176	54	previous	previous	JJ
cord-342419-liaihahj	176	55	mAbs	mAbs	NNP
cord-342419-liaihahj	176	56	identified	identify	VBN
cord-342419-liaihahj	176	57	have	have	VBP
cord-342419-liaihahj	176	58	targeted	target	VBN
cord-342419-liaihahj	176	59	the	the	DT
cord-342419-liaihahj	176	60	lower	low	JJR
cord-342419-liaihahj	176	61	half	half	NN
cord-342419-liaihahj	176	62	of	of	IN
cord-342419-liaihahj	176	63	the	the	DT
cord-342419-liaihahj	176	64	protein	protein	NN
cord-342419-liaihahj	176	65	[	[	-LRB-
cord-342419-liaihahj	176	66	43	43	CD
cord-342419-liaihahj	176	67	,	,	,
cord-342419-liaihahj	176	68	50	50	CD
cord-342419-liaihahj	176	69	,	,	,
cord-342419-liaihahj	176	70	[	[	-LRB-
cord-342419-liaihahj	176	71	52	52	CD
cord-342419-liaihahj	176	72	]	]	-RRB-
cord-342419-liaihahj	177	1	[	[	-LRB-
cord-342419-liaihahj	177	2	53	53	CD
cord-342419-liaihahj	177	3	]	]	-RRB-
cord-342419-liaihahj	178	1	[	[	-LRB-
cord-342419-liaihahj	178	2	54	54	CD
cord-342419-liaihahj	178	3	]	]	-RRB-
cord-342419-liaihahj	179	1	[	[	-LRB-
cord-342419-liaihahj	179	2	55	55	CD
cord-342419-liaihahj	179	3	]	]	-RRB-
cord-342419-liaihahj	179	4	.	.	.
cord-342419-liaihahj	180	1	The	the	DT
cord-342419-liaihahj	180	2	new	new	JJ
cord-342419-liaihahj	180	3	epitope	epitope	NN
cord-342419-liaihahj	180	4	is	be	VBZ
cord-342419-liaihahj	180	5	nearly	nearly	RB
cord-342419-liaihahj	180	6	completely	completely	RB
cord-342419-liaihahj	180	7	contained	contain	VBN
cord-342419-liaihahj	180	8	within	within	IN
cord-342419-liaihahj	180	9	the	the	DT
cord-342419-liaihahj	180	10	pre	pre	JJ
cord-342419-liaihahj	180	11	-	-	JJ
cord-342419-liaihahj	180	12	fusion	fusion	JJ
cord-342419-liaihahj	180	13	trimeric	trimeric	JJ
cord-342419-liaihahj	180	14	interface	interface	NN
cord-342419-liaihahj	180	15	of	of	IN
cord-342419-liaihahj	180	16	the	the	DT
cord-342419-liaihahj	180	17	hMPV	hmpv	NN
cord-342419-liaihahj	180	18	F	F	NNP
cord-342419-liaihahj	180	19	protein	protein	NN
cord-342419-liaihahj	180	20	,	,	,
cord-342419-liaihahj	180	21	which	which	WDT
cord-342419-liaihahj	180	22	is	be	VBZ
cord-342419-liaihahj	180	23	a	a	DT
cord-342419-liaihahj	180	24	unique	unique	JJ
cord-342419-liaihahj	180	25	feature	feature	NN
cord-342419-liaihahj	180	26	among	among	IN
cord-342419-liaihahj	180	27	previously	previously	RB
cord-342419-liaihahj	180	28	discovered	discover	VBN
cord-342419-liaihahj	180	29	human	human	NNP
cord-342419-liaihahj	180	30	mAbs	mAbs	NNP
cord-342419-liaihahj	180	31	to	to	IN
cord-342419-liaihahj	180	32	viral	viral	JJ
cord-342419-liaihahj	180	33	glycoproteins	glycoprotein	NNS
cord-342419-liaihahj	180	34	.	.	.
cord-342419-liaihahj	181	1	Although	although	IN
cord-342419-liaihahj	181	2	the	the	DT
cord-342419-liaihahj	181	3	mAbs	mabs	NN
cord-342419-liaihahj	181	4	were	be	VBD
cord-342419-liaihahj	181	5	shown	show	VBN
cord-342419-liaihahj	181	6	to	to	TO
cord-342419-liaihahj	181	7	bind	bind	VB
cord-342419-liaihahj	181	8	both	both	DT
cord-342419-liaihahj	181	9	predominantly	predominantly	RB
cord-342419-liaihahj	181	10	pre	pre	JJ
cord-342419-liaihahj	181	11	-	-	JJ
cord-342419-liaihahj	181	12	fusion	fusion	JJ
cord-342419-liaihahj	181	13	and	and	CC
cord-342419-liaihahj	181	14	postfusion	postfusion	NN
cord-342419-liaihahj	181	15	conformations	conformation	NNS
cord-342419-liaihahj	181	16	of	of	IN
cord-342419-liaihahj	181	17	the	the	DT
cord-342419-liaihahj	181	18	hMPV	hmpv	NN
cord-342419-liaihahj	181	19	F	F	NNP
cord-342419-liaihahj	181	20	protein	protein	NN
cord-342419-liaihahj	181	21	,	,	,
cord-342419-liaihahj	181	22	preferential	preferential	JJ
cord-342419-liaihahj	181	23	binding	binding	NN
cord-342419-liaihahj	181	24	to	to	IN
cord-342419-liaihahj	181	25	pre	pre	JJ
cord-342419-liaihahj	181	26	-	-	JJ
cord-342419-liaihahj	181	27	fusion	fusion	JJ
cord-342419-liaihahj	181	28	hMPV	hmpv	NN
cord-342419-liaihahj	181	29	F	F	NNP
cord-342419-liaihahj	181	30	was	be	VBD
cord-342419-liaihahj	181	31	observed	observe	VBN
cord-342419-liaihahj	181	32	as	as	IN
cord-342419-liaihahj	181	33	evidenced	evidence	VBN
cord-342419-liaihahj	181	34	by	by	IN
cord-342419-liaihahj	181	35	our	-PRON-	PRP$
cord-342419-liaihahj	181	36	attempts	attempt	NNS
cord-342419-liaihahj	181	37	to	to	TO
cord-342419-liaihahj	181	38	complex	complex	VB
cord-342419-liaihahj	181	39	MPV458	MPV458	NNP
cord-342419-liaihahj	181	40	and	and	CC
cord-342419-liaihahj	181	41	MPV465	MPV465	NNP
cord-342419-liaihahj	181	42	with	with	IN
cord-342419-liaihahj	181	43	post	post	JJ
cord-342419-liaihahj	181	44	-	-	JJ
cord-342419-liaihahj	181	45	fusion	fusion	JJ
cord-342419-liaihahj	181	46	hMPV	hmpv	NN
cord-342419-liaihahj	181	47	F.	F.	NNP
cord-342419-liaihahj	181	48	These	these	DT
cord-342419-liaihahj	181	49	data	datum	NNS
cord-342419-liaihahj	181	50	indicate	indicate	VBP
cord-342419-liaihahj	181	51	that	that	IN
cord-342419-liaihahj	181	52	while	while	IN
cord-342419-liaihahj	181	53	the	the	DT
cord-342419-liaihahj	181	54	66	66	CD
cord-342419-liaihahj	181	55	-	-	SYM
cord-342419-liaihahj	181	56	87	87	CD
cord-342419-liaihahj	181	57	epitope	epitope	NN
cord-342419-liaihahj	181	58	is	be	VBZ
cord-342419-liaihahj	181	59	present	present	JJ
cord-342419-liaihahj	181	60	in	in	IN
cord-342419-liaihahj	181	61	both	both	DT
cord-342419-liaihahj	181	62	pre	pre	JJ
cord-342419-liaihahj	181	63	-	-	JJ
cord-342419-liaihahj	181	64	fusion	fusion	JJ
cord-342419-liaihahj	181	65	and	and	CC
cord-342419-liaihahj	181	66	post	post	JJ
cord-342419-liaihahj	181	67	-	-	JJ
cord-342419-liaihahj	181	68	fusion	fusion	JJ
cord-342419-liaihahj	181	69	conformations	conformation	NNS
cord-342419-liaihahj	181	70	,	,	,
cord-342419-liaihahj	181	71	the	the	DT
cord-342419-liaihahj	181	72	complete	complete	JJ
cord-342419-liaihahj	181	73	structural	structural	JJ
cord-342419-liaihahj	181	74	epitope	epitope	NN
cord-342419-liaihahj	181	75	is	be	VBZ
cord-342419-liaihahj	181	76	present	present	JJ
cord-342419-liaihahj	181	77	only	only	RB
cord-342419-liaihahj	181	78	on	on	IN
cord-342419-liaihahj	181	79	pre	pre	JJ
cord-342419-liaihahj	181	80	-	-	JJ
cord-342419-liaihahj	181	81	fusion	fusion	JJ
cord-342419-liaihahj	181	82	hMPV	hmpv	NN
cord-342419-liaihahj	181	83	F	F	NNP
cord-342419-liaihahj	181	84	,	,	,
cord-342419-liaihahj	181	85	as	as	IN
cord-342419-liaihahj	181	86	several	several	JJ
cord-342419-liaihahj	181	87	contacts	contact	NNS
cord-342419-liaihahj	181	88	outside	outside	IN
cord-342419-liaihahj	181	89	of	of	IN
cord-342419-liaihahj	181	90	the	the	DT
cord-342419-liaihahj	181	91	66	66	CD
cord-342419-liaihahj	181	92	-	-	SYM
cord-342419-liaihahj	181	93	87	87	CD
cord-342419-liaihahj	181	94	region	region	NN
cord-342419-liaihahj	181	95	were	be	VBD
cord-342419-liaihahj	181	96	observed	observe	VBN
cord-342419-liaihahj	181	97	in	in	IN
cord-342419-liaihahj	181	98	our	-PRON-	PRP$
cord-342419-liaihahj	181	99	X	x	NN
cord-342419-liaihahj	181	100	-	-	NN
cord-342419-liaihahj	181	101	ray	ray	NN
cord-342419-liaihahj	181	102	crystal	crystal	NN
cord-342419-liaihahj	181	103	structure	structure	NN
cord-342419-liaihahj	181	104	.	.	.
cord-342419-liaihahj	182	1	These	these	DT
cord-342419-liaihahj	182	2	additional	additional	JJ
cord-342419-liaihahj	182	3	epitope	epitope	NN
cord-342419-liaihahj	182	4	residues	residue	NNS
cord-342419-liaihahj	182	5	are	be	VBP
cord-342419-liaihahj	182	6	rearranged	rearrange	VBN
cord-342419-liaihahj	182	7	in	in	IN
cord-342419-liaihahj	182	8	the	the	DT
cord-342419-liaihahj	182	9	post	post	JJ
cord-342419-liaihahj	182	10	-	-	JJ
cord-342419-liaihahj	182	11	fusion	fusion	JJ
cord-342419-liaihahj	182	12	conformation	conformation	NN
cord-342419-liaihahj	182	13	.	.	.
cord-342419-liaihahj	183	1	Human	Human	NNP
cord-342419-liaihahj	183	2	mAbs	mAbs	NNP
cord-342419-liaihahj	183	3	targeting	target	VBG
cord-342419-liaihahj	183	4	the	the	DT
cord-342419-liaihahj	183	5	trimeric	trimeric	JJ
cord-342419-liaihahj	183	6	interface	interface	NN
cord-342419-liaihahj	183	7	of	of	IN
cord-342419-liaihahj	183	8	the	the	DT
cord-342419-liaihahj	183	9	influenza	influenza	NN
cord-342419-liaihahj	183	10	HA	HA	NNP
cord-342419-liaihahj	183	11	protein	protein	NN
cord-342419-liaihahj	183	12	have	have	VBP
cord-342419-liaihahj	183	13	previously	previously	RB
cord-342419-liaihahj	183	14	been	be	VBN
cord-342419-liaihahj	183	15	discovered	discover	VBN
cord-342419-liaihahj	183	16	[	[	-LRB-
cord-342419-liaihahj	183	17	60	60	CD
cord-342419-liaihahj	183	18	]	]	-RRB-
cord-342419-liaihahj	184	1	[	[	-LRB-
cord-342419-liaihahj	184	2	61	61	CD
cord-342419-liaihahj	184	3	]	]	-RRB-
cord-342419-liaihahj	185	1	[	[	-LRB-
cord-342419-liaihahj	185	2	62	62	CD
cord-342419-liaihahj	185	3	]	]	-RRB-
cord-342419-liaihahj	185	4	[	[	-LRB-
cord-342419-liaihahj	185	5	63	63	CD
cord-342419-liaihahj	185	6	]	]	-RRB-
cord-342419-liaihahj	186	1	[	[	-LRB-
cord-342419-liaihahj	186	2	64	64	CD
cord-342419-liaihahj	186	3	]	]	-RRB-
cord-342419-liaihahj	186	4	,	,	,
cord-342419-liaihahj	186	5	yet	yet	CC
cord-342419-liaihahj	186	6	these	these	DT
cord-342419-liaihahj	186	7	mAbs	mAbs	NNP
cord-342419-liaihahj	186	8	were	be	VBD
cord-342419-liaihahj	186	9	nonneutralizing	nonneutralize	VBG
cord-342419-liaihahj	186	10	,	,	,
cord-342419-liaihahj	186	11	unlike	unlike	IN
cord-342419-liaihahj	186	12	the	the	DT
cord-342419-liaihahj	186	13	mAbs	mabs	NN
cord-342419-liaihahj	186	14	described	describe	VBN
cord-342419-liaihahj	186	15	here	here	RB
cord-342419-liaihahj	186	16	,	,	,
cord-342419-liaihahj	186	17	which	which	WDT
cord-342419-liaihahj	186	18	are	be	VBP
cord-342419-liaihahj	186	19	the	the	DT
cord-342419-liaihahj	186	20	first	first	JJ
cord-342419-liaihahj	186	21	human	human	JJ
cord-342419-liaihahj	186	22	mAbs	mAbs	NNP
cord-342419-liaihahj	186	23	discovered	discover	VBD
cord-342419-liaihahj	186	24	that	that	DT
cord-342419-liaihahj	186	25	bind	bind	NN
cord-342419-liaihahj	186	26	within	within	IN
cord-342419-liaihahj	186	27	the	the	DT
cord-342419-liaihahj	186	28	trimeric	trimeric	JJ
cord-342419-liaihahj	186	29	interface	interface	NN
cord-342419-liaihahj	186	30	of	of	IN
cord-342419-liaihahj	186	31	a	a	DT
cord-342419-liaihahj	186	32	viral	viral	JJ
cord-342419-liaihahj	186	33	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	186	34	and	and	CC
cord-342419-liaihahj	186	35	neutralize	neutralize	VB
cord-342419-liaihahj	186	36	the	the	DT
cord-342419-liaihahj	186	37	virus	virus	NN
cord-342419-liaihahj	186	38	.	.	.
cord-342419-liaihahj	187	1	As	as	IN
cord-342419-liaihahj	187	2	epitopes	epitope	NNS
cord-342419-liaihahj	187	3	at	at	IN
cord-342419-liaihahj	187	4	the	the	DT
cord-342419-liaihahj	187	5	trimeric	trimeric	NNP
cord-342419-liaihahj	187	6	interface	interface	NN
cord-342419-liaihahj	187	7	have	have	VBP
cord-342419-liaihahj	187	8	now	now	RB
cord-342419-liaihahj	187	9	been	be	VBN
cord-342419-liaihahj	187	10	determined	determine	VBN
cord-342419-liaihahj	187	11	for	for	IN
cord-342419-liaihahj	187	12	influenza	influenza	NN
cord-342419-liaihahj	187	13	virus	virus	NN
cord-342419-liaihahj	187	14	and	and	CC
cord-342419-liaihahj	187	15	hMPV	hmpv	NN
cord-342419-liaihahj	187	16	,	,	,
cord-342419-liaihahj	187	17	it	-PRON-	PRP
cord-342419-liaihahj	187	18	is	be	VBZ
cord-342419-liaihahj	187	19	likely	likely	JJ
cord-342419-liaihahj	188	1	such	such	JJ
cord-342419-liaihahj	188	2	epitopes	epitope	NNS
cord-342419-liaihahj	188	3	are	be	VBP
cord-342419-liaihahj	188	4	important	important	JJ
cord-342419-liaihahj	188	5	mediators	mediator	NNS
cord-342419-liaihahj	188	6	of	of	IN
cord-342419-liaihahj	188	7	viral	viral	JJ
cord-342419-liaihahj	188	8	immunity	immunity	NN
cord-342419-liaihahj	188	9	for	for	IN
cord-342419-liaihahj	188	10	other	other	JJ
cord-342419-liaihahj	188	11	class	class	NN
cord-342419-liaihahj	188	12	I	-PRON-	PRP
cord-342419-liaihahj	188	13	fusion	fusion	VBP
cord-342419-liaihahj	188	14	viral	viral	JJ
cord-342419-liaihahj	188	15	glycoproteins	glycoprotein	NNS
cord-342419-liaihahj	188	16	.	.	.
cord-342419-liaihahj	189	1	The	the	DT
cord-342419-liaihahj	189	2	mechanism	mechanism	NN
cord-342419-liaihahj	189	3	by	by	IN
cord-342419-liaihahj	189	4	which	which	WDT
cord-342419-liaihahj	189	5	mAbs	mAbs	NNP
cord-342419-liaihahj	189	6	MPV458	MPV458	NNP
cord-342419-liaihahj	189	7	and	and	CC
cord-342419-liaihahj	189	8	MPV465	MPV465	NNP
cord-342419-liaihahj	189	9	neutralize	neutralize	VB
cord-342419-liaihahj	189	10	hMPV	hmpv	NN
cord-342419-liaihahj	189	11	remains	remain	NNS
cord-342419-liaihahj	189	12	to	to	TO
cord-342419-liaihahj	189	13	be	be	VB
cord-342419-liaihahj	189	14	determined	determine	VBN
cord-342419-liaihahj	189	15	.	.	.
cord-342419-liaihahj	190	1	The	the	DT
cord-342419-liaihahj	190	2	mAbs	mabs	NN
cord-342419-liaihahj	190	3	could	could	MD
cord-342419-liaihahj	190	4	inhibit	inhibit	VB
cord-342419-liaihahj	190	5	the	the	DT
cord-342419-liaihahj	190	6	transition	transition	NN
cord-342419-liaihahj	190	7	of	of	IN
cord-342419-liaihahj	190	8	the	the	DT
cord-342419-liaihahj	190	9	hMPV	hmpv	NN
cord-342419-liaihahj	190	10	F	F	NNP
cord-342419-liaihahj	190	11	protein	protein	NN
cord-342419-liaihahj	190	12	from	from	IN
cord-342419-liaihahj	190	13	the	the	DT
cord-342419-liaihahj	190	14	pre	pre	JJ
cord-342419-liaihahj	190	15	-	-	NN
cord-342419-liaihahj	190	16	fusion	fusion	NN
cord-342419-liaihahj	190	17	to	to	IN
cord-342419-liaihahj	190	18	the	the	DT
cord-342419-liaihahj	190	19	post	post	JJ
cord-342419-liaihahj	190	20	-	-	JJ
cord-342419-liaihahj	190	21	fusion	fusion	JJ
cord-342419-liaihahj	190	22	conformation	conformation	NN
cord-342419-liaihahj	190	23	,	,	,
cord-342419-liaihahj	190	24	which	which	WDT
cord-342419-liaihahj	190	25	is	be	VBZ
cord-342419-liaihahj	190	26	likely	likely	RB
cord-342419-liaihahj	190	27	the	the	DT
cord-342419-liaihahj	190	28	mechanism	mechanism	NN
cord-342419-liaihahj	190	29	for	for	IN
cord-342419-liaihahj	190	30	the	the	DT
cord-342419-liaihahj	190	31	majority	majority	NN
cord-342419-liaihahj	190	32	of	of	IN
cord-342419-liaihahj	190	33	antibodies	antibody	NNS
cord-342419-liaihahj	190	34	targeting	target	VBG
cord-342419-liaihahj	190	35	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	190	36	fusion	fusion	NN
cord-342419-liaihahj	190	37	proteins	protein	NNS
cord-342419-liaihahj	190	38	.	.	.
cord-342419-liaihahj	191	1	Alternatively	alternatively	RB
cord-342419-liaihahj	191	2	,	,	,
cord-342419-liaihahj	191	3	the	the	DT
cord-342419-liaihahj	191	4	mAbs	mAbs	NNP
cord-342419-liaihahj	191	5	could	could	MD
cord-342419-liaihahj	191	6	prevent	prevent	VB
cord-342419-liaihahj	191	7	infection	infection	NN
cord-342419-liaihahj	191	8	by	by	IN
cord-342419-liaihahj	191	9	disrupting	disrupt	VBG
cord-342419-liaihahj	191	10	the	the	DT
cord-342419-liaihahj	191	11	trimeric	trimeric	JJ
cord-342419-liaihahj	191	12	structure	structure	NN
cord-342419-liaihahj	191	13	of	of	IN
cord-342419-liaihahj	191	14	the	the	DT
cord-342419-liaihahj	191	15	hMPV	hmpv	NN
cord-342419-liaihahj	191	16	F	F	NNP
cord-342419-liaihahj	191	17	protein	protein	NN
cord-342419-liaihahj	191	18	.	.	.
cord-342419-liaihahj	192	1	Currently	currently	RB
cord-342419-liaihahj	192	2	,	,	,
cord-342419-liaihahj	192	3	we	-PRON-	PRP
cord-342419-liaihahj	192	4	do	do	VBP
cord-342419-liaihahj	192	5	not	not	RB
cord-342419-liaihahj	192	6	have	have	VB
cord-342419-liaihahj	192	7	reliable	reliable	JJ
cord-342419-liaihahj	192	8	prefusion	prefusion	NN
cord-342419-liaihahj	192	9	constructs	construct	NNS
cord-342419-liaihahj	192	10	that	that	WDT
cord-342419-liaihahj	192	11	could	could	MD
cord-342419-liaihahj	192	12	be	be	VB
cord-342419-liaihahj	192	13	used	use	VBN
cord-342419-liaihahj	192	14	to	to	TO
cord-342419-liaihahj	192	15	examine	examine	VB
cord-342419-liaihahj	192	16	this	this	DT
cord-342419-liaihahj	192	17	hypothesis	hypothesis	NN
cord-342419-liaihahj	192	18	.	.	.
cord-342419-liaihahj	193	1	It	-PRON-	PRP
cord-342419-liaihahj	193	2	is	be	VBZ
cord-342419-liaihahj	193	3	clear	clear	JJ
cord-342419-liaihahj	193	4	that	that	IN
cord-342419-liaihahj	193	5	MPV458	MPV458	NNP
cord-342419-liaihahj	193	6	binds	bind	VBZ
cord-342419-liaihahj	193	7	to	to	IN
cord-342419-liaihahj	193	8	the	the	DT
cord-342419-liaihahj	193	9	surface	surface	NN
cord-342419-liaihahj	193	10	of	of	IN
cord-342419-liaihahj	193	11	infected	infected	JJ
cord-342419-liaihahj	193	12	cells	cell	NNS
cord-342419-liaihahj	193	13	as	as	IN
cord-342419-liaihahj	193	14	demonstrated	demonstrate	VBN
cord-342419-liaihahj	193	15	by	by	IN
cord-342419-liaihahj	193	16	our	-PRON-	PRP$
cord-342419-liaihahj	193	17	analysis	analysis	NN
cord-342419-liaihahj	193	18	by	by	IN
cord-342419-liaihahj	193	19	flow	flow	NN
cord-342419-liaihahj	193	20	cytometry	cytometry	NN
cord-342419-liaihahj	193	21	,	,	,
cord-342419-liaihahj	193	22	although	although	IN
cord-342419-liaihahj	193	23	it	-PRON-	PRP
cord-342419-liaihahj	193	24	is	be	VBZ
cord-342419-liaihahj	193	25	unclear	unclear	JJ
cord-342419-liaihahj	193	26	if	if	IN
cord-342419-liaihahj	193	27	the	the	DT
cord-342419-liaihahj	193	28	mAb	mab	NN
cord-342419-liaihahj	193	29	is	be	VBZ
cord-342419-liaihahj	193	30	binding	bind	VBG
cord-342419-liaihahj	193	31	to	to	IN
cord-342419-liaihahj	193	32	trimeric	trimeric	JJ
cord-342419-liaihahj	193	33	or	or	CC
cord-342419-liaihahj	193	34	monomeric	monomeric	JJ
cord-342419-liaihahj	193	35	hMPV	hmpv	NN
cord-342419-liaihahj	193	36	F	F	NNP
cord-342419-liaihahj	193	37	on	on	IN
cord-342419-liaihahj	193	38	the	the	DT
cord-342419-liaihahj	193	39	cell	cell	NN
cord-342419-liaihahj	193	40	surface	surface	NN
cord-342419-liaihahj	193	41	.	.	.
cord-342419-liaihahj	194	1	Since	since	IN
cord-342419-liaihahj	194	2	the	the	DT
cord-342419-liaihahj	194	3	66	66	CD
cord-342419-liaihahj	194	4	-	-	SYM
cord-342419-liaihahj	194	5	87	87	CD
cord-342419-liaihahj	194	6	epitope	epitope	NN
cord-342419-liaihahj	194	7	is	be	VBZ
cord-342419-liaihahj	194	8	hidden	hide	VBN
cord-342419-liaihahj	194	9	within	within	IN
cord-342419-liaihahj	194	10	the	the	DT
cord-342419-liaihahj	194	11	trimeric	trimeric	JJ
cord-342419-liaihahj	194	12	interface	interface	NN
cord-342419-liaihahj	194	13	of	of	IN
cord-342419-liaihahj	194	14	the	the	DT
cord-342419-liaihahj	194	15	previously	previously	RB
cord-342419-liaihahj	194	16	determined	determine	VBN
cord-342419-liaihahj	194	17	X	x	NN
cord-342419-liaihahj	194	18	-	-	NN
cord-342419-liaihahj	194	19	ray	ray	NN
cord-342419-liaihahj	194	20	Antibody	Antibody	NNP
cord-342419-liaihahj	194	21	recognition	recognition	NN
cord-342419-liaihahj	194	22	of	of	IN
cord-342419-liaihahj	194	23	the	the	DT
cord-342419-liaihahj	194	24	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	194	25	fusion	fusion	NN
cord-342419-liaihahj	194	26	protein	protein	NN
cord-342419-liaihahj	194	27	trimer	trimer	NN
cord-342419-liaihahj	194	28	interface	interface	NN
cord-342419-liaihahj	194	29	crystal	crystal	NN
cord-342419-liaihahj	194	30	structure	structure	NN
cord-342419-liaihahj	194	31	of	of	IN
cord-342419-liaihahj	194	32	pre	pre	JJ
cord-342419-liaihahj	194	33	-	-	JJ
cord-342419-liaihahj	194	34	fusion	fusion	JJ
cord-342419-liaihahj	194	35	hMPV	hmpv	NN
cord-342419-liaihahj	194	36	F	F	NNP
cord-342419-liaihahj	194	37	[	[	-LRB-
cord-342419-liaihahj	194	38	38	38	CD
cord-342419-liaihahj	194	39	]	]	-RRB-
cord-342419-liaihahj	194	40	,	,	,
cord-342419-liaihahj	194	41	a	a	DT
cord-342419-liaihahj	194	42	mechanism	mechanism	NN
cord-342419-liaihahj	194	43	must	must	MD
cord-342419-liaihahj	194	44	occur	occur	VB
cord-342419-liaihahj	194	45	whereby	whereby	WRB
cord-342419-liaihahj	194	46	the	the	DT
cord-342419-liaihahj	194	47	hMPV	hmpv	NN
cord-342419-liaihahj	194	48	F	F	NNP
cord-342419-liaihahj	194	49	protein	protein	NN
cord-342419-liaihahj	194	50	motion	motion	NN
cord-342419-liaihahj	194	51	facilitates	facilitate	VBZ
cord-342419-liaihahj	194	52	exposure	exposure	NN
cord-342419-liaihahj	194	53	of	of	IN
cord-342419-liaihahj	194	54	the	the	DT
cord-342419-liaihahj	194	55	epitope	epitope	NN
cord-342419-liaihahj	194	56	for	for	IN
cord-342419-liaihahj	194	57	MPV458	MPV458	NNP
cord-342419-liaihahj	194	58	binding	bind	VBG
cord-342419-liaihahj	194	59	,	,	,
cord-342419-liaihahj	194	60	and	and	CC
cord-342419-liaihahj	194	61	indeed	indeed	RB
cord-342419-liaihahj	194	62	for	for	IN
cord-342419-liaihahj	194	63	initial	initial	JJ
cord-342419-liaihahj	194	64	naïve	naïve	JJ
cord-342419-liaihahj	194	65	B	B	NNP
cord-342419-liaihahj	194	66	cell	cell	NN
cord-342419-liaihahj	194	67	recognition	recognition	NN
cord-342419-liaihahj	194	68	of	of	IN
cord-342419-liaihahj	194	69	this	this	DT
cord-342419-liaihahj	194	70	epitope	epitope	NN
cord-342419-liaihahj	194	71	since	since	IN
cord-342419-liaihahj	194	72	these	these	DT
cord-342419-liaihahj	194	73	mAbs	mAbs	NNP
cord-342419-liaihahj	194	74	were	be	VBD
cord-342419-liaihahj	194	75	derived	derive	VBN
cord-342419-liaihahj	194	76	from	from	IN
cord-342419-liaihahj	194	77	seropositive	seropositive	JJ
cord-342419-liaihahj	194	78	human	human	JJ
cord-342419-liaihahj	194	79	subjects	subject	NNS
cord-342419-liaihahj	194	80	.	.	.
cord-342419-liaihahj	195	1	This	this	DT
cord-342419-liaihahj	195	2	motion	motion	NN
cord-342419-liaihahj	195	3	,	,	,
cord-342419-liaihahj	195	4	termed	term	VBN
cord-342419-liaihahj	195	5	"	"	``
cord-342419-liaihahj	195	6	breathing	breathing	NN
cord-342419-liaihahj	195	7	"	"	''
cord-342419-liaihahj	195	8	has	have	VBZ
cord-342419-liaihahj	195	9	previously	previously	RB
cord-342419-liaihahj	195	10	been	be	VBN
cord-342419-liaihahj	195	11	demonstrated	demonstrate	VBN
cord-342419-liaihahj	195	12	for	for	IN
cord-342419-liaihahj	195	13	the	the	DT
cord-342419-liaihahj	195	14	RSV	RSV	NNP
cord-342419-liaihahj	195	15	F	F	NNP
cord-342419-liaihahj	195	16	protein	protein	NN
cord-342419-liaihahj	195	17	by	by	IN
cord-342419-liaihahj	195	18	identification	identification	NN
cord-342419-liaihahj	195	19	of	of	IN
cord-342419-liaihahj	195	20	an	an	DT
cord-342419-liaihahj	195	21	alternative	alternative	JJ
cord-342419-liaihahj	195	22	conformation	conformation	NN
cord-342419-liaihahj	195	23	of	of	IN
cord-342419-liaihahj	195	24	the	the	DT
cord-342419-liaihahj	195	25	RSV	RSV	NNP
cord-342419-liaihahj	195	26	F	F	NNP
cord-342419-liaihahj	195	27	protein	protein	NN
cord-342419-liaihahj	195	28	,	,	,
cord-342419-liaihahj	195	29	whereby	whereby	WRB
cord-342419-liaihahj	195	30	the	the	DT
cord-342419-liaihahj	195	31	mAb	mAb	NNP
cord-342419-liaihahj	195	32	CR9501	CR9501	NNP
cord-342419-liaihahj	195	33	causes	cause	VBZ
cord-342419-liaihahj	195	34	opening	opening	NN
cord-342419-liaihahj	195	35	of	of	IN
cord-342419-liaihahj	195	36	pre	pre	JJ
cord-342419-liaihahj	195	37	-	-	JJ
cord-342419-liaihahj	195	38	fusion	fusion	JJ
cord-342419-liaihahj	195	39	RSV	RSV	NNP
cord-342419-liaihahj	195	40	F	F	NNP
cord-342419-liaihahj	195	41	trimers	trimer	NNS
cord-342419-liaihahj	195	42	,	,	,
cord-342419-liaihahj	195	43	and	and	CC
cord-342419-liaihahj	195	44	RSV	RSV	NNP
cord-342419-liaihahj	195	45	F	F	NNP
cord-342419-liaihahj	195	46	was	be	VBD
cord-342419-liaihahj	195	47	also	also	RB
cord-342419-liaihahj	195	48	found	find	VBN
cord-342419-liaihahj	195	49	to	to	TO
cord-342419-liaihahj	195	50	be	be	VB
cord-342419-liaihahj	195	51	both	both	DT
cord-342419-liaihahj	195	52	monomeric	monomeric	JJ
cord-342419-liaihahj	195	53	and	and	CC
cord-342419-liaihahj	195	54	trimeric	trimeric	JJ
cord-342419-liaihahj	195	55	on	on	IN
cord-342419-liaihahj	195	56	the	the	DT
cord-342419-liaihahj	195	57	surface	surface	NN
cord-342419-liaihahj	195	58	of	of	IN
cord-342419-liaihahj	195	59	transfected	transfecte	VBN
cord-342419-liaihahj	195	60	HEK293F	HEK293F	NNP
cord-342419-liaihahj	195	61	cells	cell	NNS
cord-342419-liaihahj	195	62	[	[	-LRB-
cord-342419-liaihahj	195	63	65	65	CD
cord-342419-liaihahj	195	64	]	]	-RRB-
cord-342419-liaihahj	195	65	.	.	.
cord-342419-liaihahj	196	1	Furthermore	furthermore	RB
cord-342419-liaihahj	196	2	,	,	,
cord-342419-liaihahj	196	3	breathing	breathing	NN
cord-342419-liaihahj	196	4	of	of	IN
cord-342419-liaihahj	196	5	influenza	influenza	NN
cord-342419-liaihahj	196	6	and	and	CC
cord-342419-liaihahj	196	7	HIV	HIV	NNP
cord-342419-liaihahj	196	8	glycoproteins	glycoprotein	NNS
cord-342419-liaihahj	196	9	has	have	VBZ
cord-342419-liaihahj	196	10	also	also	RB
cord-342419-liaihahj	196	11	been	be	VBN
cord-342419-liaihahj	196	12	described	describe	VBN
cord-342419-liaihahj	196	13	[	[	-LRB-
cord-342419-liaihahj	196	14	67	67	CD
cord-342419-liaihahj	196	15	,	,	,
cord-342419-liaihahj	196	16	68	68	CD
cord-342419-liaihahj	196	17	]	]	-RRB-
cord-342419-liaihahj	196	18	,	,	,
cord-342419-liaihahj	196	19	and	and	CC
cord-342419-liaihahj	196	20	mAbs	mAbs	NNP
cord-342419-liaihahj	196	21	to	to	IN
cord-342419-liaihahj	196	22	the	the	DT
cord-342419-liaihahj	196	23	HIV	HIV	NNP
cord-342419-liaihahj	196	24	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	196	25	have	have	VBP
cord-342419-liaihahj	196	26	been	be	VBN
cord-342419-liaihahj	196	27	shown	show	VBN
cord-342419-liaihahj	196	28	to	to	TO
cord-342419-liaihahj	196	29	destabilize	destabilize	VB
cord-342419-liaihahj	196	30	the	the	DT
cord-342419-liaihahj	196	31	trimeric	trimeric	JJ
cord-342419-liaihahj	196	32	structure	structure	NN
cord-342419-liaihahj	196	33	[	[	-LRB-
cord-342419-liaihahj	196	34	69	69	CD
cord-342419-liaihahj	196	35	]	]	-RRB-
cord-342419-liaihahj	196	36	.	.	.
cord-342419-liaihahj	197	1	The	the	DT
cord-342419-liaihahj	197	2	mAb	mAb	NNP
cord-342419-liaihahj	197	3	CR9501	CR9501	NNP
cord-342419-liaihahj	197	4	targets	target	VBZ
cord-342419-liaihahj	197	5	antigenic	antigenic	JJ
cord-342419-liaihahj	197	6	site	site	NN
cord-342419-liaihahj	197	7	V	v	NN
cord-342419-liaihahj	197	8	of	of	IN
cord-342419-liaihahj	197	9	the	the	DT
cord-342419-liaihahj	197	10	RSV	RSV	NNP
cord-342419-liaihahj	197	11	F	F	NNP
cord-342419-liaihahj	197	12	protein	protein	NN
cord-342419-liaihahj	197	13	,	,	,
cord-342419-liaihahj	197	14	which	which	WDT
cord-342419-liaihahj	197	15	was	be	VBD
cord-342419-liaihahj	197	16	previously	previously	RB
cord-342419-liaihahj	197	17	defined	define	VBN
cord-342419-liaihahj	197	18	by	by	IN
cord-342419-liaihahj	197	19	the	the	DT
cord-342419-liaihahj	197	20	mAb	mAb	NNS
cord-342419-liaihahj	197	21	hRSV90	hRSV90	NNP
cord-342419-liaihahj	197	22	[	[	-LRB-
cord-342419-liaihahj	197	23	45	45	CD
cord-342419-liaihahj	197	24	]	]	-RRB-
cord-342419-liaihahj	197	25	.	.	.
cord-342419-liaihahj	198	1	mAbs	mabs	NN
cord-342419-liaihahj	198	2	to	to	IN
cord-342419-liaihahj	198	3	a	a	DT
cord-342419-liaihahj	198	4	similar	similar	JJ
cord-342419-liaihahj	198	5	antigenic	antigenic	JJ
cord-342419-liaihahj	198	6	site	site	NN
cord-342419-liaihahj	198	7	V	v	NN
cord-342419-liaihahj	198	8	epitope	epitope	NN
cord-342419-liaihahj	198	9	on	on	IN
cord-342419-liaihahj	198	10	the	the	DT
cord-342419-liaihahj	198	11	hMPV	hmpv	NN
cord-342419-liaihahj	198	12	F	F	NNP
cord-342419-liaihahj	198	13	protein	protein	NN
cord-342419-liaihahj	198	14	have	have	VBP
cord-342419-liaihahj	198	15	not	not	RB
cord-342419-liaihahj	198	16	been	be	VBN
cord-342419-liaihahj	198	17	identified	identify	VBN
cord-342419-liaihahj	198	18	,	,	,
cord-342419-liaihahj	198	19	and	and	CC
cord-342419-liaihahj	198	20	MPV458	MPV458	NNP
cord-342419-liaihahj	198	21	targets	target	VBZ
cord-342419-liaihahj	198	22	an	an	DT
cord-342419-liaihahj	198	23	epitope	epitope	NN
cord-342419-liaihahj	198	24	on	on	IN
cord-342419-liaihahj	198	25	the	the	DT
cord-342419-liaihahj	198	26	opposite	opposite	JJ
cord-342419-liaihahj	198	27	face	face	NN
cord-342419-liaihahj	198	28	of	of	IN
cord-342419-liaihahj	198	29	monomeric	monomeric	JJ
cord-342419-liaihahj	198	30	hMPV	hmpv	NN
cord-342419-liaihahj	198	31	F.	f.	NN
cord-342419-liaihahj	199	1	Although	although	IN
cord-342419-liaihahj	199	2	we	-PRON-	PRP
cord-342419-liaihahj	199	3	have	have	VBP
cord-342419-liaihahj	199	4	identified	identify	VBN
cord-342419-liaihahj	199	5	a	a	DT
cord-342419-liaihahj	199	6	new	new	JJ
cord-342419-liaihahj	199	7	antigenic	antigenic	JJ
cord-342419-liaihahj	199	8	site	site	NN
cord-342419-liaihahj	199	9	by	by	IN
cord-342419-liaihahj	199	10	isolating	isolate	VBG
cord-342419-liaihahj	199	11	two	two	CD
cord-342419-liaihahj	199	12	mAbs	mabs	NN
cord-342419-liaihahj	199	13	from	from	IN
cord-342419-liaihahj	199	14	different	different	JJ
cord-342419-liaihahj	199	15	donors	donor	NNS
cord-342419-liaihahj	199	16	,	,	,
cord-342419-liaihahj	199	17	it	-PRON-	PRP
cord-342419-liaihahj	199	18	remains	remain	VBZ
cord-342419-liaihahj	199	19	unclear	unclear	JJ
cord-342419-liaihahj	199	20	if	if	IN
cord-342419-liaihahj	199	21	such	such	JJ
cord-342419-liaihahj	199	22	antibodies	antibody	NNS
cord-342419-liaihahj	199	23	are	be	VBP
cord-342419-liaihahj	199	24	a	a	DT
cord-342419-liaihahj	199	25	major	major	JJ
cord-342419-liaihahj	199	26	part	part	NN
cord-342419-liaihahj	199	27	of	of	IN
cord-342419-liaihahj	199	28	the	the	DT
cord-342419-liaihahj	199	29	hMPV	hmpv	NN
cord-342419-liaihahj	199	30	F	F	NNP
cord-342419-liaihahj	199	31	humoral	humoral	JJ
cord-342419-liaihahj	199	32	immune	immune	JJ
cord-342419-liaihahj	199	33	response	response	NN
cord-342419-liaihahj	199	34	.	.	.
cord-342419-liaihahj	200	1	It	-PRON-	PRP
cord-342419-liaihahj	200	2	also	also	RB
cord-342419-liaihahj	200	3	remains	remain	VBZ
cord-342419-liaihahj	200	4	to	to	TO
cord-342419-liaihahj	200	5	be	be	VB
cord-342419-liaihahj	200	6	determined	determine	VBN
cord-342419-liaihahj	200	7	if	if	IN
cord-342419-liaihahj	200	8	mAbs	mabs	NN
cord-342419-liaihahj	200	9	such	such	JJ
cord-342419-liaihahj	200	10	as	as	IN
cord-342419-liaihahj	200	11	MPV458	MPV458	NNP
cord-342419-liaihahj	200	12	will	will	MD
cord-342419-liaihahj	200	13	protect	protect	VB
cord-342419-liaihahj	200	14	against	against	IN
cord-342419-liaihahj	200	15	viral	viral	JJ
cord-342419-liaihahj	200	16	replication	replication	NN
cord-342419-liaihahj	200	17	in	in	IN
cord-342419-liaihahj	200	18	vivo	vivo	NNP
cord-342419-liaihahj	200	19	.	.	.
cord-342419-liaihahj	201	1	Since	since	IN
cord-342419-liaihahj	201	2	the	the	DT
cord-342419-liaihahj	201	3	MPV458	MPV458	NNP
cord-342419-liaihahj	201	4	epitope	epitope	NN
cord-342419-liaihahj	201	5	is	be	VBZ
cord-342419-liaihahj	201	6	partially	partially	RB
cord-342419-liaihahj	201	7	linear	linear	JJ
cord-342419-liaihahj	201	8	,	,	,
cord-342419-liaihahj	201	9	as	as	IN
cord-342419-liaihahj	201	10	evidenced	evidence	VBN
cord-342419-liaihahj	201	11	by	by	IN
cord-342419-liaihahj	201	12	our	-PRON-	PRP$
cord-342419-liaihahj	201	13	binding	bind	VBG
cord-342419-liaihahj	201	14	studies	study	NNS
cord-342419-liaihahj	201	15	to	to	IN
cord-342419-liaihahj	201	16	reduced	reduce	VBN
cord-342419-liaihahj	201	17	hMPV	hmpv	NN
cord-342419-liaihahj	201	18	F	F	NNP
cord-342419-liaihahj	201	19	,	,	,
cord-342419-liaihahj	201	20	a	a	DT
cord-342419-liaihahj	201	21	peptide	peptide	NN
cord-342419-liaihahj	201	22	-	-	HYPH
cord-342419-liaihahj	201	23	based	base	VBN
cord-342419-liaihahj	201	24	vaccine	vaccine	NN
cord-342419-liaihahj	201	25	based	base	VBN
cord-342419-liaihahj	201	26	solely	solely	RB
cord-342419-liaihahj	201	27	around	around	IN
cord-342419-liaihahj	201	28	this	this	DT
cord-342419-liaihahj	201	29	epitope	epitope	NN
cord-342419-liaihahj	201	30	may	may	MD
cord-342419-liaihahj	201	31	elicit	elicit	VB
cord-342419-liaihahj	201	32	neutralizing	neutralize	VBG
cord-342419-liaihahj	201	33	antibodies	antibody	NNS
cord-342419-liaihahj	201	34	.	.	.
cord-342419-liaihahj	202	1	Additionally	additionally	RB
cord-342419-liaihahj	202	2	,	,	,
cord-342419-liaihahj	202	3	although	although	IN
cord-342419-liaihahj	202	4	MPV458	MPV458	NNP
cord-342419-liaihahj	202	5	and	and	CC
cord-342419-liaihahj	202	6	MPV465	MPV465	NNP
cord-342419-liaihahj	202	7	target	target	VB
cord-342419-liaihahj	202	8	a	a	DT
cord-342419-liaihahj	202	9	similar	similar	JJ
cord-342419-liaihahj	202	10	epitope	epitope	NN
cord-342419-liaihahj	202	11	based	base	VBN
cord-342419-liaihahj	202	12	on	on	IN
cord-342419-liaihahj	202	13	epitope	epitope	NN
cord-342419-liaihahj	202	14	binning	binning	NN
cord-342419-liaihahj	202	15	analysis	analysis	NN
cord-342419-liaihahj	202	16	,	,	,
cord-342419-liaihahj	202	17	the	the	DT
cord-342419-liaihahj	202	18	binding	bind	VBG
cord-342419-liaihahj	202	19	properties	property	NNS
cord-342419-liaihahj	202	20	to	to	IN
cord-342419-liaihahj	202	21	trimeric	trimeric	NNP
cord-342419-liaihahj	202	22	hMPV	hMPV	NNP
cord-342419-liaihahj	202	23	F	F	NNP
cord-342419-liaihahj	202	24	are	be	VBP
cord-342419-liaihahj	202	25	quite	quite	RB
cord-342419-liaihahj	202	26	distinct	distinct	JJ
cord-342419-liaihahj	202	27	.	.	.
cord-342419-liaihahj	203	1	MPV458	MPV458	NNP
cord-342419-liaihahj	203	2	shows	show	VBZ
cord-342419-liaihahj	203	3	binding	bind	VBG
cord-342419-liaihahj	203	4	to	to	IN
cord-342419-liaihahj	203	5	both	both	CC
cord-342419-liaihahj	203	6	monomeric	monomeric	JJ
cord-342419-liaihahj	203	7	and	and	CC
cord-342419-liaihahj	203	8	trimeric	trimeric	NNP
cord-342419-liaihahj	203	9	hMPV	hMPV	NNP
cord-342419-liaihahj	203	10	F	F	NNP
cord-342419-liaihahj	203	11	constructs	construct	NNS
cord-342419-liaihahj	203	12	,	,	,
cord-342419-liaihahj	203	13	while	while	IN
cord-342419-liaihahj	203	14	binding	bind	VBG
cord-342419-liaihahj	203	15	to	to	IN
cord-342419-liaihahj	203	16	trimeric	trimeric	NNP
cord-342419-liaihahj	203	17	hMPV	hmpv	NN
cord-342419-liaihahj	203	18	F	F	NNP
cord-342419-liaihahj	203	19	is	be	VBZ
cord-342419-liaihahj	203	20	completely	completely	RB
cord-342419-liaihahj	203	21	eliminated	eliminate	VBN
cord-342419-liaihahj	203	22	for	for	IN
cord-342419-liaihahj	203	23	MPV465	MPV465	NNP
cord-342419-liaihahj	203	24	.	.	.
cord-342419-liaihahj	204	1	Further	further	JJ
cord-342419-liaihahj	204	2	structural	structural	JJ
cord-342419-liaihahj	204	3	analysis	analysis	NN
cord-342419-liaihahj	204	4	of	of	IN
cord-342419-liaihahj	204	5	the	the	DT
cord-342419-liaihahj	204	6	MPV465	MPV465	NNP
cord-342419-liaihahj	204	7	epitope	epitope	NN
cord-342419-liaihahj	204	8	will	will	MD
cord-342419-liaihahj	204	9	delineate	delineate	VB
cord-342419-liaihahj	204	10	the	the	DT
cord-342419-liaihahj	204	11	differential	differential	JJ
cord-342419-liaihahj	204	12	binding	bind	VBG
cord-342419-liaihahj	204	13	properties	property	NNS
cord-342419-liaihahj	204	14	.	.	.
cord-342419-liaihahj	205	1	Our	-PRON-	PRP$
cord-342419-liaihahj	205	2	findings	finding	NNS
cord-342419-liaihahj	205	3	provide	provide	VBP
cord-342419-liaihahj	205	4	novel	novel	JJ
cord-342419-liaihahj	205	5	insights	insight	NNS
cord-342419-liaihahj	205	6	on	on	IN
cord-342419-liaihahj	205	7	the	the	DT
cord-342419-liaihahj	205	8	human	human	JJ
cord-342419-liaihahj	205	9	antibody	antibody	NN
cord-342419-liaihahj	205	10	response	response	NN
cord-342419-liaihahj	205	11	to	to	IN
cord-342419-liaihahj	205	12	the	the	DT
cord-342419-liaihahj	205	13	hMPV	hmpv	NN
cord-342419-liaihahj	205	14	F	F	NNP
cord-342419-liaihahj	205	15	protein	protein	NN
cord-342419-liaihahj	205	16	,	,	,
cord-342419-liaihahj	205	17	and	and	CC
cord-342419-liaihahj	205	18	responses	response	NNS
cord-342419-liaihahj	205	19	to	to	IN
cord-342419-liaihahj	205	20	viral	viral	JJ
cord-342419-liaihahj	205	21	glycoproteins	glycoprotein	NNS
cord-342419-liaihahj	205	22	.	.	.
cord-342419-liaihahj	206	1	The	the	DT
cord-342419-liaihahj	206	2	X	x	NN
cord-342419-liaihahj	206	3	-	-	NN
cord-342419-liaihahj	206	4	ray	ray	NN
cord-342419-liaihahj	206	5	crystal	crystal	NN
cord-342419-liaihahj	206	6	structure	structure	NN
cord-342419-liaihahj	206	7	of	of	IN
cord-342419-liaihahj	206	8	the	the	DT
cord-342419-liaihahj	206	9	immune	immune	JJ
cord-342419-liaihahj	206	10	complex	complex	NN
cord-342419-liaihahj	206	11	may	may	MD
cord-342419-liaihahj	206	12	guide	guide	VB
cord-342419-liaihahj	206	13	the	the	DT
cord-342419-liaihahj	206	14	development	development	NN
cord-342419-liaihahj	206	15	of	of	IN
cord-342419-liaihahj	206	16	vaccines	vaccine	NNS
cord-342419-liaihahj	206	17	against	against	IN
cord-342419-liaihahj	206	18	hMPV	hmpv	NN
cord-342419-liaihahj	206	19	.	.	.
cord-342419-liaihahj	207	1	In	in	IN
cord-342419-liaihahj	207	2	addition	addition	NN
cord-342419-liaihahj	207	3	,	,	,
cord-342419-liaihahj	207	4	MPV458	MPV458	NNP
cord-342419-liaihahj	207	5	can	can	MD
cord-342419-liaihahj	207	6	be	be	VB
cord-342419-liaihahj	207	7	potentially	potentially	RB
cord-342419-liaihahj	207	8	applied	apply	VBN
cord-342419-liaihahj	207	9	to	to	IN
cord-342419-liaihahj	207	10	the	the	DT
cord-342419-liaihahj	207	11	treatment	treatment	NN
cord-342419-liaihahj	207	12	and	and	CC
cord-342419-liaihahj	207	13	prevention	prevention	NN
cord-342419-liaihahj	207	14	of	of	IN
cord-342419-liaihahj	207	15	hMPV	hmpv	NN
cord-342419-liaihahj	207	16	infection	infection	NN
cord-342419-liaihahj	207	17	if	if	IN
cord-342419-liaihahj	207	18	prophylactic	prophylactic	JJ
cord-342419-liaihahj	207	19	efficacy	efficacy	NN
cord-342419-liaihahj	207	20	is	be	VBZ
cord-342419-liaihahj	207	21	demonstrated	demonstrate	VBN
cord-342419-liaihahj	207	22	in	in	IN
cord-342419-liaihahj	207	23	animal	animal	NN
cord-342419-liaihahj	207	24	challenge	challenge	NN
cord-342419-liaihahj	207	25	models	model	NNS
cord-342419-liaihahj	207	26	.	.	.
cord-342419-liaihahj	208	1	This	this	DT
cord-342419-liaihahj	208	2	study	study	NN
cord-342419-liaihahj	208	3	was	be	VBD
cord-342419-liaihahj	208	4	approved	approve	VBN
cord-342419-liaihahj	208	5	by	by	IN
cord-342419-liaihahj	208	6	the	the	DT
cord-342419-liaihahj	208	7	University	University	NNP
cord-342419-liaihahj	208	8	of	of	IN
cord-342419-liaihahj	208	9	Georgia	Georgia	NNP
cord-342419-liaihahj	208	10	Institutional	Institutional	NNP
cord-342419-liaihahj	208	11	Review	Review	NNP
cord-342419-liaihahj	208	12	Board	Board	NNP
cord-342419-liaihahj	208	13	as	as	IN
cord-342419-liaihahj	208	14	STUDY00005127	STUDY00005127	NNP
cord-342419-liaihahj	208	15	.	.	.
cord-342419-liaihahj	209	1	Healthy	healthy	JJ
cord-342419-liaihahj	209	2	human	human	JJ
cord-342419-liaihahj	209	3	donors	donor	NNS
cord-342419-liaihahj	209	4	were	be	VBD
cord-342419-liaihahj	209	5	recruited	recruit	VBN
cord-342419-liaihahj	209	6	to	to	IN
cord-342419-liaihahj	209	7	the	the	DT
cord-342419-liaihahj	209	8	University	University	NNP
cord-342419-liaihahj	209	9	of	of	IN
cord-342419-liaihahj	209	10	Georgia	Georgia	NNP
cord-342419-liaihahj	209	11	Clinical	Clinical	NNP
cord-342419-liaihahj	209	12	and	and	CC
cord-342419-liaihahj	209	13	Translational	Translational	NNP
cord-342419-liaihahj	209	14	Research	Research	NNP
cord-342419-liaihahj	209	15	Unit	Unit	NNP
cord-342419-liaihahj	209	16	and	and	CC
cord-342419-liaihahj	209	17	written	write	VBN
cord-342419-liaihahj	209	18	informed	informed	JJ
cord-342419-liaihahj	209	19	consent	consent	NN
cord-342419-liaihahj	209	20	was	be	VBD
cord-342419-liaihahj	209	21	obtained	obtain	VBN
cord-342419-liaihahj	209	22	.	.	.
cord-342419-liaihahj	210	1	After	after	IN
cord-342419-liaihahj	210	2	obtaining	obtain	VBG
cord-342419-liaihahj	210	3	informed	informed	JJ
cord-342419-liaihahj	210	4	consent	consent	NN
cord-342419-liaihahj	210	5	,	,	,
cord-342419-liaihahj	210	6	90	90	CD
cord-342419-liaihahj	210	7	mL	ml	NN
cord-342419-liaihahj	210	8	of	of	IN
cord-342419-liaihahj	210	9	blood	blood	NN
cord-342419-liaihahj	210	10	was	be	VBD
cord-342419-liaihahj	210	11	drawn	draw	VBN
cord-342419-liaihahj	210	12	by	by	IN
cord-342419-liaihahj	210	13	venipuncture	venipuncture	NN
cord-342419-liaihahj	210	14	into	into	IN
cord-342419-liaihahj	210	15	9	9	CD
cord-342419-liaihahj	210	16	heparincoated	heparincoate	VBN
cord-342419-liaihahj	210	17	tubes	tube	NNS
cord-342419-liaihahj	210	18	,	,	,
cord-342419-liaihahj	210	19	and	and	CC
cord-342419-liaihahj	210	20	10	10	CD
cord-342419-liaihahj	210	21	mL	mL	NNS
cord-342419-liaihahj	210	22	of	of	IN
cord-342419-liaihahj	210	23	blood	blood	NN
cord-342419-liaihahj	210	24	was	be	VBD
cord-342419-liaihahj	210	25	collected	collect	VBN
cord-342419-liaihahj	210	26	into	into	IN
cord-342419-liaihahj	210	27	a	a	DT
cord-342419-liaihahj	210	28	serum	serum	NN
cord-342419-liaihahj	210	29	separator	separator	NN
cord-342419-liaihahj	210	30	tube	tube	NN
cord-342419-liaihahj	210	31	.	.	.
cord-342419-liaihahj	211	1	Peripheral	peripheral	JJ
cord-342419-liaihahj	211	2	blood	blood	NN
cord-342419-liaihahj	211	3	mononuclear	mononuclear	NN
cord-342419-liaihahj	211	4	cells	cell	NNS
cord-342419-liaihahj	211	5	(	(	-LRB-
cord-342419-liaihahj	211	6	PBMCs	pbmc	NNS
cord-342419-liaihahj	211	7	)	)	-RRB-
cord-342419-liaihahj	211	8	were	be	VBD
cord-342419-liaihahj	211	9	isolated	isolate	VBN
cord-342419-liaihahj	211	10	from	from	IN
cord-342419-liaihahj	211	11	human	human	JJ
cord-342419-liaihahj	211	12	donor	donor	NN
cord-342419-liaihahj	211	13	blood	blood	NN
cord-342419-liaihahj	211	14	samples	sample	NNS
cord-342419-liaihahj	211	15	using	use	VBG
cord-342419-liaihahj	211	16	Ficoll	Ficoll	NNP
cord-342419-liaihahj	211	17	-	-	HYPH
cord-342419-liaihahj	211	18	Histopaque	Histopaque	NNP
cord-342419-liaihahj	211	19	density	density	NN
cord-342419-liaihahj	211	20	gradient	gradient	NN
cord-342419-liaihahj	211	21	centrifugation	centrifugation	NN
cord-342419-liaihahj	211	22	,	,	,
cord-342419-liaihahj	211	23	and	and	CC
cord-342419-liaihahj	211	24	PBMCs	pbmc	NNS
cord-342419-liaihahj	211	25	were	be	VBD
cord-342419-liaihahj	211	26	frozen	freeze	VBN
cord-342419-liaihahj	211	27	in	in	IN
cord-342419-liaihahj	211	28	the	the	DT
cord-342419-liaihahj	211	29	liquid	liquid	JJ
cord-342419-liaihahj	211	30	nitrogen	nitrogen	NN
cord-342419-liaihahj	211	31	vapor	vapor	NN
cord-342419-liaihahj	211	32	phase	phase	NN
cord-342419-liaihahj	211	33	until	until	IN
cord-342419-liaihahj	211	34	further	further	JJ
cord-342419-liaihahj	211	35	use	use	NN
cord-342419-liaihahj	211	36	.	.	.
cord-342419-liaihahj	212	1	Plasmids	plasmid	NNS
cord-342419-liaihahj	212	2	encoding	encode	VBG
cord-342419-liaihahj	212	3	cDNAs	cdna	VBZ
cord-342419-liaihahj	212	4	for	for	IN
cord-342419-liaihahj	212	5	hMPV	hmpv	NN
cord-342419-liaihahj	212	6	F	F	NNP
cord-342419-liaihahj	212	7	proteins	protein	NNS
cord-342419-liaihahj	212	8	listed	list	VBN
cord-342419-liaihahj	212	9	in	in	IN
cord-342419-liaihahj	212	10	S1	S1	NNP
cord-342419-liaihahj	212	11	Table	Table	NNP
cord-342419-liaihahj	212	12	were	be	VBD
cord-342419-liaihahj	212	13	synthesized	synthesize	VBN
cord-342419-liaihahj	213	1	(	(	-LRB-
cord-342419-liaihahj	213	2	Gen	Gen	NNP
cord-342419-liaihahj	213	3	-	-	HYPH
cord-342419-liaihahj	213	4	Script	Script	NNP
cord-342419-liaihahj	213	5	)	)	-RRB-
cord-342419-liaihahj	213	6	and	and	CC
cord-342419-liaihahj	213	7	cloned	clone	VBN
cord-342419-liaihahj	213	8	into	into	IN
cord-342419-liaihahj	213	9	the	the	DT
cord-342419-liaihahj	213	10	pcDNA3.1	pcdna3.1	NN
cord-342419-liaihahj	213	11	+	+	CC
cord-342419-liaihahj	213	12	vector	vector	NN
cord-342419-liaihahj	213	13	.	.	.
cord-342419-liaihahj	214	1	The	the	DT
cord-342419-liaihahj	214	2	plasmids	plasmid	NNS
cord-342419-liaihahj	214	3	were	be	VBD
cord-342419-liaihahj	214	4	expanded	expand	VBN
cord-342419-liaihahj	214	5	by	by	IN
cord-342419-liaihahj	214	6	transformation	transformation	NN
cord-342419-liaihahj	214	7	in	in	IN
cord-342419-liaihahj	214	8	Escherichia	Escherichia	NNP
cord-342419-liaihahj	214	9	coli	coli	NNS
cord-342419-liaihahj	214	10	DH5α	DH5α	NNP
cord-342419-liaihahj	214	11	cells	cell	NNS
cord-342419-liaihahj	214	12	with	with	IN
cord-342419-liaihahj	214	13	100	100	CD
cord-342419-liaihahj	214	14	μg	μg	NN
cord-342419-liaihahj	214	15	/	/	SYM
cord-342419-liaihahj	214	16	mL	ml	NN
cord-342419-liaihahj	214	17	of	of	IN
cord-342419-liaihahj	214	18	ampicillin	ampicillin	NN
cord-342419-liaihahj	214	19	(	(	-LRB-
cord-342419-liaihahj	214	20	Thermo	Thermo	NNP
cord-342419-liaihahj	214	21	Fisher	Fisher	NNP
cord-342419-liaihahj	214	22	Scientific	Scientific	NNP
cord-342419-liaihahj	214	23	)	)	-RRB-
cord-342419-liaihahj	214	24	for	for	IN
cord-342419-liaihahj	214	25	selection	selection	NN
cord-342419-liaihahj	214	26	.	.	.
cord-342419-liaihahj	215	1	Plasmids	plasmid	NNS
cord-342419-liaihahj	215	2	were	be	VBD
cord-342419-liaihahj	215	3	purified	purify	VBN
cord-342419-liaihahj	215	4	using	use	VBG
cord-342419-liaihahj	215	5	the	the	DT
cord-342419-liaihahj	215	6	EZNA	EZNA	NNP
cord-342419-liaihahj	215	7	plasmid	plasmid	NN
cord-342419-liaihahj	215	8	maxi	maxi	NNP
cord-342419-liaihahj	215	9	kit	kit	NNP
cord-342419-liaihahj	215	10	(	(	-LRB-
cord-342419-liaihahj	215	11	Omega	Omega	NNP
cord-342419-liaihahj	215	12	BioTek	BioTek	NNP
cord-342419-liaihahj	215	13	)	)	-RRB-
cord-342419-liaihahj	215	14	,	,	,
cord-342419-liaihahj	215	15	Antibody	antibody	NN
cord-342419-liaihahj	215	16	recognition	recognition	NN
cord-342419-liaihahj	215	17	of	of	IN
cord-342419-liaihahj	215	18	the	the	DT
cord-342419-liaihahj	215	19	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	215	20	fusion	fusion	NN
cord-342419-liaihahj	215	21	protein	protein	NN
cord-342419-liaihahj	215	22	trimer	trimer	NN
cord-342419-liaihahj	215	23	interface	interface	NN
cord-342419-liaihahj	215	24	according	accord	VBG
cord-342419-liaihahj	215	25	to	to	IN
cord-342419-liaihahj	215	26	the	the	DT
cord-342419-liaihahj	215	27	manufacturer	manufacturer	NN
cord-342419-liaihahj	215	28	's	's	POS
cord-342419-liaihahj	215	29	protocol	protocol	NN
cord-342419-liaihahj	215	30	.	.	.
cord-342419-liaihahj	216	1	To	to	TO
cord-342419-liaihahj	216	2	generate	generate	VB
cord-342419-liaihahj	216	3	stable	stable	JJ
cord-342419-liaihahj	216	4	cell	cell	NN
cord-342419-liaihahj	216	5	lines	line	NNS
cord-342419-liaihahj	216	6	that	that	WDT
cord-342419-liaihahj	216	7	express	express	VBP
cord-342419-liaihahj	216	8	hMPV	hmpv	NN
cord-342419-liaihahj	216	9	B2	B2	NNP
cord-342419-liaihahj	216	10	F	F	NNP
cord-342419-liaihahj	216	11	,	,	,
cord-342419-liaihahj	216	12	hMPV	hmpv	NN
cord-342419-liaihahj	216	13	B2	B2	NNP
cord-342419-liaihahj	216	14	F	F	NNP
cord-342419-liaihahj	216	15	-	-	HYPH
cord-342419-liaihahj	216	16	GCN4	GCN4	NNP
cord-342419-liaihahj	216	17	,	,	,
cord-342419-liaihahj	216	18	and	and	CC
cord-342419-liaihahj	216	19	hMPV	hmpv	NN
cord-342419-liaihahj	216	20	F	F	NNP
cord-342419-liaihahj	216	21	130-BV	130-bv	CD
cord-342419-liaihahj	216	22	,	,	,
cord-342419-liaihahj	216	23	Expi293F	Expi293F	NNP
cord-342419-liaihahj	216	24	(	(	-LRB-
cord-342419-liaihahj	216	25	Thermo	Thermo	NNP
cord-342419-liaihahj	216	26	Fisher	Fisher	NNP
cord-342419-liaihahj	216	27	Scientific	Scientific	NNP
cord-342419-liaihahj	216	28	)	)	-RRB-
cord-342419-liaihahj	216	29	cells	cell	NNS
cord-342419-liaihahj	216	30	were	be	VBD
cord-342419-liaihahj	216	31	plated	plate	VBN
cord-342419-liaihahj	216	32	into	into	IN
cord-342419-liaihahj	216	33	a	a	DT
cord-342419-liaihahj	216	34	12	12	CD
cord-342419-liaihahj	216	35	well	well	NN
cord-342419-liaihahj	216	36	plate	plate	NN
cord-342419-liaihahj	216	37	(	(	-LRB-
cord-342419-liaihahj	216	38	4	4	CD
cord-342419-liaihahj	216	39	x	x	SYM
cord-342419-liaihahj	216	40	10	10	CD
cord-342419-liaihahj	216	41	5	5	CD
cord-342419-liaihahj	216	42	per	per	IN
cord-342419-liaihahj	216	43	well	well	RB
cord-342419-liaihahj	216	44	)	)	-RRB-
cord-342419-liaihahj	216	45	with	with	IN
cord-342419-liaihahj	216	46	1	1	CD
cord-342419-liaihahj	216	47	mL	ml	NN
cord-342419-liaihahj	216	48	of	of	IN
cord-342419-liaihahj	216	49	growth	growth	NN
cord-342419-liaihahj	216	50	medium	medium	NN
cord-342419-liaihahj	216	51	(	(	-LRB-
cord-342419-liaihahj	216	52	Dulbecco	Dulbecco	NNP
cord-342419-liaihahj	216	53	's	's	POS
cord-342419-liaihahj	216	54	Modified	modify	VBN
cord-342419-liaihahj	216	55	Eagle	Eagle	NNP
cord-342419-liaihahj	216	56	Medium	Medium	NNP
cord-342419-liaihahj	216	57	(	(	-LRB-
cord-342419-liaihahj	216	58	Corning	Corning	NNP
cord-342419-liaihahj	216	59	)	)	-RRB-
cord-342419-liaihahj	216	60	,	,	,
cord-342419-liaihahj	216	61	10	10	CD
cord-342419-liaihahj	216	62	%	%	NN
cord-342419-liaihahj	216	63	fetal	fetal	JJ
cord-342419-liaihahj	216	64	bovine	bovine	JJ
cord-342419-liaihahj	216	65	serum	serum	NN
cord-342419-liaihahj	216	66	(	(	-LRB-
cord-342419-liaihahj	216	67	Corning	Corning	NNP
cord-342419-liaihahj	216	68	)	)	-RRB-
cord-342419-liaihahj	216	69	)	)	-RRB-
cord-342419-liaihahj	217	1	1	1	CD
cord-342419-liaihahj	217	2	day	day	NN
cord-342419-liaihahj	217	3	before	before	IN
cord-342419-liaihahj	217	4	transfection	transfection	NN
cord-342419-liaihahj	217	5	.	.	.
cord-342419-liaihahj	218	1	For	for	IN
cord-342419-liaihahj	218	2	each	each	DT
cord-342419-liaihahj	218	3	milliliter	milliliter	NN
cord-342419-liaihahj	218	4	of	of	IN
cord-342419-liaihahj	218	5	transfection	transfection	NN
cord-342419-liaihahj	218	6	,	,	,
cord-342419-liaihahj	218	7	1	1	CD
cord-342419-liaihahj	218	8	μg	μg	NN
cord-342419-liaihahj	218	9	of	of	IN
cord-342419-liaihahj	218	10	plasmid	plasmid	NNP
cord-342419-liaihahj	218	11	DNA	DNA	NNP
cord-342419-liaihahj	218	12	was	be	VBD
cord-342419-liaihahj	218	13	mixed	mix	VBN
cord-342419-liaihahj	218	14	with	with	IN
cord-342419-liaihahj	218	15	4	4	CD
cord-342419-liaihahj	218	16	μg	μg	CD
cord-342419-liaihahj	218	17	of	of	IN
cord-342419-liaihahj	218	18	25,000-molecular	25,000-molecular	CD
cord-342419-liaihahj	218	19	-	-	HYPH
cord-342419-liaihahj	218	20	weight	weight	NN
cord-342419-liaihahj	218	21	polyethylenimine	polyethylenimine	NN
cord-342419-liaihahj	218	22	(	(	-LRB-
cord-342419-liaihahj	218	23	PEI	PEI	NNP
cord-342419-liaihahj	218	24	;	;	:
cord-342419-liaihahj	218	25	PolySciences	PolySciences	NNP
cord-342419-liaihahj	218	26	Inc.	Inc.	NNP
cord-342419-liaihahj	218	27	)	)	-RRB-
cord-342419-liaihahj	218	28	in	in	IN
cord-342419-liaihahj	218	29	66.67	66.67	CD
cord-342419-liaihahj	218	30	μl	μl	IN
cord-342419-liaihahj	218	31	Opti	Opti	NNP
cord-342419-liaihahj	218	32	-	-	HYPH
cord-342419-liaihahj	218	33	MEM	mem	NN
cord-342419-liaihahj	218	34	cell	cell	NN
cord-342419-liaihahj	218	35	culture	culture	NN
cord-342419-liaihahj	218	36	medium	medium	NN
cord-342419-liaihahj	218	37	(	(	-LRB-
cord-342419-liaihahj	218	38	Gibco	Gibco	NNP
cord-342419-liaihahj	218	39	)	)	-RRB-
cord-342419-liaihahj	218	40	.	.	.
cord-342419-liaihahj	219	1	After	after	IN
cord-342419-liaihahj	219	2	30	30	CD
cord-342419-liaihahj	219	3	min	min	NN
cord-342419-liaihahj	219	4	,	,	,
cord-342419-liaihahj	219	5	the	the	DT
cord-342419-liaihahj	219	6	DNA	DNA	NNP
cord-342419-liaihahj	219	7	-	-	HYPH
cord-342419-liaihahj	219	8	PEI	PEI	NNP
cord-342419-liaihahj	219	9	mixture	mixture	NN
cord-342419-liaihahj	219	10	was	be	VBD
cord-342419-liaihahj	219	11	added	add	VBN
cord-342419-liaihahj	219	12	to	to	IN
cord-342419-liaihahj	219	13	HEK293F	HEK293F	NNP
cord-342419-liaihahj	219	14	cells	cell	NNS
cord-342419-liaihahj	219	15	in	in	IN
cord-342419-liaihahj	219	16	Opti	Opti	NNP
cord-342419-liaihahj	219	17	-	-	HYPH
cord-342419-liaihahj	219	18	MEM	mem	NN
cord-342419-liaihahj	219	19	.	.	.
cord-342419-liaihahj	220	1	After	after	IN
cord-342419-liaihahj	220	2	3	3	CD
cord-342419-liaihahj	220	3	to	to	TO
cord-342419-liaihahj	220	4	4	4	CD
cord-342419-liaihahj	220	5	days	day	NNS
cord-342419-liaihahj	220	6	,	,	,
cord-342419-liaihahj	220	7	20	20	CD
cord-342419-liaihahj	220	8	μl	μl	NN
cord-342419-liaihahj	220	9	of	of	IN
cord-342419-liaihahj	220	10	cell	cell	NN
cord-342419-liaihahj	220	11	culture	culture	NN
cord-342419-liaihahj	220	12	supernatant	supernatant	NN
cord-342419-liaihahj	220	13	was	be	VBD
cord-342419-liaihahj	220	14	used	use	VBN
cord-342419-liaihahj	220	15	for	for	IN
cord-342419-liaihahj	220	16	western	western	JJ
cord-342419-liaihahj	220	17	blot	blot	NN
cord-342419-liaihahj	220	18	to	to	TO
cord-342419-liaihahj	220	19	determine	determine	VB
cord-342419-liaihahj	220	20	protein	protein	NN
cord-342419-liaihahj	220	21	expression	expression	NN
cord-342419-liaihahj	220	22	.	.	.
cord-342419-liaihahj	221	1	Then	then	RB
cord-342419-liaihahj	221	2	,	,	,
cord-342419-liaihahj	221	3	the	the	DT
cord-342419-liaihahj	221	4	culture	culture	NN
cord-342419-liaihahj	221	5	medium	medium	NN
cord-342419-liaihahj	221	6	was	be	VBD
cord-342419-liaihahj	221	7	replaced	replace	VBN
cord-342419-liaihahj	221	8	with	with	IN
cord-342419-liaihahj	221	9	1	1	CD
cord-342419-liaihahj	221	10	mL	ml	NN
cord-342419-liaihahj	221	11	growth	growth	NN
cord-342419-liaihahj	221	12	medium	medium	NN
cord-342419-liaihahj	221	13	supplemented	supplement	VBN
cord-342419-liaihahj	221	14	with	with	IN
cord-342419-liaihahj	221	15	G418	G418	NNPS
cord-342419-liaihahj	221	16	(	(	-LRB-
cord-342419-liaihahj	221	17	Geneticin	Geneticin	NNP
cord-342419-liaihahj	221	18	;	;	:
cord-342419-liaihahj	221	19	VWR	VWR	NNP
cord-342419-liaihahj	221	20	)	)	-RRB-
cord-342419-liaihahj	221	21	antibiotic	antibiotic	JJ
cord-342419-liaihahj	221	22	to	to	IN
cord-342419-liaihahj	221	23	a	a	DT
cord-342419-liaihahj	221	24	final	final	JJ
cord-342419-liaihahj	221	25	concentration	concentration	NN
cord-342419-liaihahj	221	26	of	of	IN
cord-342419-liaihahj	221	27	250	250	CD
cord-342419-liaihahj	221	28	μg	μg	NNS
cord-342419-liaihahj	221	29	/	/	SYM
cord-342419-liaihahj	221	30	mL.	mL.	NNS
cord-342419-liaihahj	221	31	After	after	IN
cord-342419-liaihahj	221	32	2	2	CD
cord-342419-liaihahj	221	33	-	-	SYM
cord-342419-liaihahj	221	34	3	3	CD
cord-342419-liaihahj	221	35	days	day	NNS
cord-342419-liaihahj	221	36	,	,	,
cord-342419-liaihahj	221	37	HEK293F	HEK293F	NNP
cord-342419-liaihahj	221	38	cells	cell	NNS
cord-342419-liaihahj	221	39	were	be	VBD
cord-342419-liaihahj	221	40	resuspended	resuspend	VBN
cord-342419-liaihahj	221	41	with	with	IN
cord-342419-liaihahj	221	42	the	the	DT
cord-342419-liaihahj	221	43	growth	growth	NN
cord-342419-liaihahj	221	44	medium	medium	NN
cord-342419-liaihahj	221	45	supplemented	supplement	VBN
cord-342419-liaihahj	221	46	with	with	IN
cord-342419-liaihahj	221	47	G418	G418	NNPS
cord-342419-liaihahj	221	48	,	,	,
cord-342419-liaihahj	221	49	and	and	CC
cord-342419-liaihahj	221	50	expanded	expand	VBD
cord-342419-liaihahj	221	51	to	to	IN
cord-342419-liaihahj	221	52	a	a	DT
cord-342419-liaihahj	221	53	25-cm	25-cm	CD
cord-342419-liaihahj	221	54	2	2	CD
cord-342419-liaihahj	221	55	cell	cell	NN
cord-342419-liaihahj	221	56	culture	culture	NN
cord-342419-liaihahj	221	57	flask	flask	NN
cord-342419-liaihahj	221	58	.	.	.
cord-342419-liaihahj	222	1	Cells	cell	NNS
cord-342419-liaihahj	222	2	were	be	VBD
cord-342419-liaihahj	222	3	trypsinized	trypsinize	VBN
cord-342419-liaihahj	222	4	once	once	IN
cord-342419-liaihahj	222	5	they	-PRON-	PRP
cord-342419-liaihahj	222	6	reach	reach	VBP
cord-342419-liaihahj	222	7	80	80	CD
cord-342419-liaihahj	222	8	-	-	SYM
cord-342419-liaihahj	222	9	90	90	CD
cord-342419-liaihahj	222	10	%	%	NN
cord-342419-liaihahj	222	11	confluency	confluency	NN
cord-342419-liaihahj	222	12	and	and	CC
cord-342419-liaihahj	222	13	further	further	RB
cord-342419-liaihahj	222	14	expanded	expand	VBD
cord-342419-liaihahj	222	15	to	to	IN
cord-342419-liaihahj	222	16	a	a	DT
cord-342419-liaihahj	222	17	75-cm	75-cm	CD
cord-342419-liaihahj	222	18	2	2	CD
cord-342419-liaihahj	222	19	cell	cell	NN
cord-342419-liaihahj	222	20	culture	culture	NN
cord-342419-liaihahj	222	21	flask	flask	NN
cord-342419-liaihahj	222	22	.	.	.
cord-342419-liaihahj	223	1	Again	again	RB
cord-342419-liaihahj	223	2	,	,	,
cord-342419-liaihahj	223	3	at	at	IN
cord-342419-liaihahj	223	4	80	80	CD
cord-342419-liaihahj	223	5	-	-	SYM
cord-342419-liaihahj	223	6	90	90	CD
cord-342419-liaihahj	223	7	%	%	NN
cord-342419-liaihahj	223	8	confluency	confluency	NN
cord-342419-liaihahj	223	9	,	,	,
cord-342419-liaihahj	223	10	trypsinized	trypsinize	VBD
cord-342419-liaihahj	223	11	the	the	DT
cord-342419-liaihahj	223	12	cells	cell	NNS
cord-342419-liaihahj	223	13	were	be	VBD
cord-342419-liaihahj	223	14	transferred	transfer	VBN
cord-342419-liaihahj	223	15	to	to	IN
cord-342419-liaihahj	223	16	a	a	DT
cord-342419-liaihahj	223	17	250	250	CD
cord-342419-liaihahj	223	18	mL	ml	NN
cord-342419-liaihahj	223	19	flask	flask	NN
cord-342419-liaihahj	223	20	in	in	IN
cord-342419-liaihahj	223	21	100	100	CD
cord-342419-liaihahj	223	22	mL	ml	NN
cord-342419-liaihahj	223	23	Freestyle293	Freestyle293	NNP
cord-342419-liaihahj	223	24	medium	medium	NN
cord-342419-liaihahj	223	25	(	(	-LRB-
cord-342419-liaihahj	223	26	Gibco	Gibco	NNP
cord-342419-liaihahj	223	27	)	)	-RRB-
cord-342419-liaihahj	223	28	supplemented	supplement	VBN
cord-342419-liaihahj	223	29	with	with	IN
cord-342419-liaihahj	223	30	G418	G418	NNS
cord-342419-liaihahj	223	31	and	and	CC
cord-342419-liaihahj	223	32	cultured	culture	VBN
cord-342419-liaihahj	223	33	in	in	IN
cord-342419-liaihahj	223	34	shaking	shake	VBG
cord-342419-liaihahj	223	35	incubator	incubator	NN
cord-342419-liaihahj	223	36	at	at	IN
cord-342419-liaihahj	223	37	37˚C	37˚c	CD
cord-342419-liaihahj	223	38	with	with	IN
cord-342419-liaihahj	223	39	5	5	CD
cord-342419-liaihahj	223	40	%	%	NN
cord-342419-liaihahj	223	41	CO	co	NN
cord-342419-liaihahj	223	42	2	2	CD
cord-342419-liaihahj	223	43	.	.	.
cord-342419-liaihahj	224	1	For	for	IN
cord-342419-liaihahj	224	2	protein	protein	NN
cord-342419-liaihahj	224	3	expression	expression	NN
cord-342419-liaihahj	224	4	and	and	CC
cord-342419-liaihahj	224	5	purification	purification	NN
cord-342419-liaihahj	224	6	,	,	,
cord-342419-liaihahj	224	7	the	the	DT
cord-342419-liaihahj	224	8	stable	stable	JJ
cord-342419-liaihahj	224	9	cell	cell	NN
cord-342419-liaihahj	224	10	lines	line	NNS
cord-342419-liaihahj	224	11	were	be	VBD
cord-342419-liaihahj	224	12	expanded	expand	VBN
cord-342419-liaihahj	224	13	in	in	IN
cord-342419-liaihahj	224	14	500	500	CD
cord-342419-liaihahj	224	15	mL	ml	NN
cord-342419-liaihahj	224	16	of	of	IN
cord-342419-liaihahj	224	17	Freestyle293	Freestyle293	NNP
cord-342419-liaihahj	224	18	medium	medium	NN
cord-342419-liaihahj	224	19	supplemented	supplement	VBN
cord-342419-liaihahj	224	20	with	with	IN
cord-342419-liaihahj	224	21	G418	G418	NNS
cord-342419-liaihahj	224	22	.	.	.
cord-342419-liaihahj	225	1	The	the	DT
cord-342419-liaihahj	225	2	remaining	remain	VBG
cord-342419-liaihahj	225	3	constructs	construct	NNS
cord-342419-liaihahj	225	4	are	be	VBP
cord-342419-liaihahj	225	5	expressed	express	VBN
cord-342419-liaihahj	225	6	by	by	IN
cord-342419-liaihahj	225	7	transient	transient	JJ
cord-342419-liaihahj	225	8	transfection	transfection	NN
cord-342419-liaihahj	225	9	of	of	IN
cord-342419-liaihahj	225	10	Expi293F	expi293f	NN
cord-342419-liaihahj	225	11	cells	cell	NNS
cord-342419-liaihahj	225	12	.	.	.
cord-342419-liaihahj	226	1	After	after	IN
cord-342419-liaihahj	226	2	5	5	CD
cord-342419-liaihahj	226	3	to	to	TO
cord-342419-liaihahj	226	4	7	7	CD
cord-342419-liaihahj	226	5	days	day	NNS
cord-342419-liaihahj	226	6	,	,	,
cord-342419-liaihahj	226	7	the	the	DT
cord-342419-liaihahj	226	8	cultures	culture	NNS
cord-342419-liaihahj	226	9	were	be	VBD
cord-342419-liaihahj	226	10	centrifuged	centrifuge	VBN
cord-342419-liaihahj	226	11	to	to	IN
cord-342419-liaihahj	226	12	pellet	pellet	NN
cord-342419-liaihahj	226	13	the	the	DT
cord-342419-liaihahj	226	14	cells	cell	NNS
cord-342419-liaihahj	226	15	,	,	,
cord-342419-liaihahj	226	16	and	and	CC
cord-342419-liaihahj	226	17	the	the	DT
cord-342419-liaihahj	226	18	supernatants	supernatant	NNS
cord-342419-liaihahj	226	19	were	be	VBD
cord-342419-liaihahj	226	20	filtered	filter	VBN
cord-342419-liaihahj	226	21	through	through	IN
cord-342419-liaihahj	226	22	a	a	DT
cord-342419-liaihahj	226	23	0.45-μm	0.45-μm	CD
cord-342419-liaihahj	226	24	sterile	sterile	JJ
cord-342419-liaihahj	226	25	filter	filter	NN
cord-342419-liaihahj	226	26	.	.	.
cord-342419-liaihahj	227	1	Recombinant	recombinant	JJ
cord-342419-liaihahj	227	2	proteins	protein	NNS
cord-342419-liaihahj	227	3	were	be	VBD
cord-342419-liaihahj	227	4	purified	purify	VBN
cord-342419-liaihahj	227	5	directly	directly	RB
cord-342419-liaihahj	227	6	from	from	IN
cord-342419-liaihahj	227	7	the	the	DT
cord-342419-liaihahj	227	8	filtered	filter	VBN
cord-342419-liaihahj	227	9	culture	culture	NN
cord-342419-liaihahj	227	10	supernatants	supernatant	NNS
cord-342419-liaihahj	227	11	using	use	VBG
cord-342419-liaihahj	227	12	HisTrap	HisTrap	NNP
cord-342419-liaihahj	227	13	Excel	Excel	NNP
cord-342419-liaihahj	227	14	columns	column	NNS
cord-342419-liaihahj	227	15	(	(	-LRB-
cord-342419-liaihahj	227	16	GE	GE	NNP
cord-342419-liaihahj	227	17	Healthcare	Healthcare	NNP
cord-342419-liaihahj	227	18	Life	Life	NNP
cord-342419-liaihahj	227	19	Sciences	Sciences	NNPS
cord-342419-liaihahj	227	20	)	)	-RRB-
cord-342419-liaihahj	227	21	.	.	.
cord-342419-liaihahj	228	1	Each	each	DT
cord-342419-liaihahj	228	2	column	column	NN
cord-342419-liaihahj	228	3	was	be	VBD
cord-342419-liaihahj	228	4	stored	store	VBN
cord-342419-liaihahj	228	5	in	in	IN
cord-342419-liaihahj	228	6	20	20	CD
cord-342419-liaihahj	228	7	%	%	NN
cord-342419-liaihahj	228	8	ethanol	ethanol	NN
cord-342419-liaihahj	228	9	and	and	CC
cord-342419-liaihahj	228	10	washed	wash	VBD
cord-342419-liaihahj	228	11	with	with	IN
cord-342419-liaihahj	228	12	5	5	CD
cord-342419-liaihahj	228	13	column	column	NN
cord-342419-liaihahj	228	14	volumes	volume	NNS
cord-342419-liaihahj	228	15	(	(	-LRB-
cord-342419-liaihahj	228	16	CV	CV	NNP
cord-342419-liaihahj	228	17	)	)	-RRB-
cord-342419-liaihahj	228	18	of	of	IN
cord-342419-liaihahj	228	19	wash	wash	NN
cord-342419-liaihahj	228	20	buffer	buffer	NN
cord-342419-liaihahj	228	21	(	(	-LRB-
cord-342419-liaihahj	228	22	20	20	CD
cord-342419-liaihahj	228	23	mM	mM	NNP
cord-342419-liaihahj	228	24	Tris	Tris	NNP
cord-342419-liaihahj	228	25	pH	pH	NNP
cord-342419-liaihahj	228	26	7.5	7.5	CD
cord-342419-liaihahj	228	27	,	,	,
cord-342419-liaihahj	228	28	500	500	CD
cord-342419-liaihahj	228	29	mM	mm	CD
cord-342419-liaihahj	228	30	NaCl	nacl	NN
cord-342419-liaihahj	228	31	,	,	,
cord-342419-liaihahj	228	32	and	and	CC
cord-342419-liaihahj	228	33	20	20	CD
cord-342419-liaihahj	228	34	mM	mm	CD
cord-342419-liaihahj	228	35	imidazole	imidazole	NN
cord-342419-liaihahj	228	36	)	)	-RRB-
cord-342419-liaihahj	228	37	before	before	IN
cord-342419-liaihahj	228	38	loading	load	VBG
cord-342419-liaihahj	228	39	samples	sample	NNS
cord-342419-liaihahj	228	40	onto	onto	IN
cord-342419-liaihahj	228	41	the	the	DT
cord-342419-liaihahj	228	42	column	column	NN
cord-342419-liaihahj	228	43	.	.	.
cord-342419-liaihahj	229	1	After	after	IN
cord-342419-liaihahj	229	2	sample	sample	NN
cord-342419-liaihahj	229	3	application	application	NN
cord-342419-liaihahj	229	4	,	,	,
cord-342419-liaihahj	229	5	columns	column	NNS
cord-342419-liaihahj	229	6	were	be	VBD
cord-342419-liaihahj	229	7	washed	wash	VBN
cord-342419-liaihahj	229	8	with	with	IN
cord-342419-liaihahj	229	9	10	10	CD
cord-342419-liaihahj	229	10	CV	CV	NNP
cord-342419-liaihahj	229	11	of	of	IN
cord-342419-liaihahj	229	12	wash	wash	NN
cord-342419-liaihahj	229	13	buffer	buffer	NN
cord-342419-liaihahj	229	14	.	.	.
cord-342419-liaihahj	230	1	Proteins	protein	NNS
cord-342419-liaihahj	230	2	were	be	VBD
cord-342419-liaihahj	230	3	eluted	elute	VBN
cord-342419-liaihahj	230	4	from	from	IN
cord-342419-liaihahj	230	5	the	the	DT
cord-342419-liaihahj	230	6	column	column	NN
cord-342419-liaihahj	230	7	with	with	IN
cord-342419-liaihahj	230	8	6	6	CD
cord-342419-liaihahj	230	9	CV	CV	NNP
cord-342419-liaihahj	230	10	of	of	IN
cord-342419-liaihahj	230	11	elution	elution	NN
cord-342419-liaihahj	230	12	buffer	buffer	NN
cord-342419-liaihahj	230	13	(	(	-LRB-
cord-342419-liaihahj	230	14	20	20	CD
cord-342419-liaihahj	230	15	mM	mM	NNP
cord-342419-liaihahj	230	16	Tris	Tris	NNP
cord-342419-liaihahj	230	17	pH	pH	NNP
cord-342419-liaihahj	230	18	7.5	7.5	CD
cord-342419-liaihahj	230	19	,	,	,
cord-342419-liaihahj	230	20	500	500	CD
cord-342419-liaihahj	230	21	mM	mm	CD
cord-342419-liaihahj	230	22	NaCl	nacl	NN
cord-342419-liaihahj	230	23	,	,	,
cord-342419-liaihahj	230	24	and	and	CC
cord-342419-liaihahj	230	25	250	250	CD
cord-342419-liaihahj	230	26	mM	mm	CD
cord-342419-liaihahj	230	27	imidazole	imidazole	NN
cord-342419-liaihahj	230	28	)	)	-RRB-
cord-342419-liaihahj	230	29	.	.	.
cord-342419-liaihahj	231	1	Proteins	protein	NNS
cord-342419-liaihahj	231	2	were	be	VBD
cord-342419-liaihahj	231	3	concentrated	concentrate	VBN
cord-342419-liaihahj	231	4	and	and	CC
cord-342419-liaihahj	231	5	buffer	buffer	NN
cord-342419-liaihahj	231	6	exchanged	exchange	VBN
cord-342419-liaihahj	231	7	into	into	IN
cord-342419-liaihahj	231	8	phosphate	phosphate	NN
cord-342419-liaihahj	231	9	buffered	buffer	VBN
cord-342419-liaihahj	231	10	saline	saline	NN
cord-342419-liaihahj	231	11	(	(	-LRB-
cord-342419-liaihahj	231	12	PBS	PBS	NNP
cord-342419-liaihahj	231	13	)	)	-RRB-
cord-342419-liaihahj	231	14	using	use	VBG
cord-342419-liaihahj	231	15	Amicon	Amicon	NNP
cord-342419-liaihahj	231	16	Ultra-15	Ultra-15	NNP
cord-342419-liaihahj	231	17	centrifugal	centrifugal	JJ
cord-342419-liaihahj	231	18	filter	filter	NN
cord-342419-liaihahj	231	19	units	unit	NNS
cord-342419-liaihahj	231	20	with	with	IN
cord-342419-liaihahj	231	21	a	a	DT
cord-342419-liaihahj	231	22	30-kDa	30-kda	CD
cord-342419-liaihahj	231	23	cutoff	cutoff	NN
cord-342419-liaihahj	231	24	(	(	-LRB-
cord-342419-liaihahj	231	25	Millipore	Millipore	NNP
cord-342419-liaihahj	231	26	Sigma	Sigma	NNP
cord-342419-liaihahj	231	27	)	)	-RRB-
cord-342419-liaihahj	231	28	.	.	.
cord-342419-liaihahj	232	1	In	in	IN
cord-342419-liaihahj	232	2	order	order	NN
cord-342419-liaihahj	232	3	to	to	TO
cord-342419-liaihahj	232	4	generate	generate	VB
cord-342419-liaihahj	232	5	homogeneous	homogeneous	JJ
cord-342419-liaihahj	232	6	cleaved	cleave	VBN
cord-342419-liaihahj	232	7	trimeric	trimeric	NNP
cord-342419-liaihahj	232	8	hMPV	hmpv	NN
cord-342419-liaihahj	232	9	F	F	NNP
cord-342419-liaihahj	232	10	,	,	,
cord-342419-liaihahj	232	11	TPCK	TPCK	NNP
cord-342419-liaihahj	232	12	(	(	-LRB-
cord-342419-liaihahj	232	13	L-1-tosylamido-2-phenylethyl	L-1-tosylamido-2-phenylethyl	NNP
cord-342419-liaihahj	232	14	chloromethyl	chloromethyl	NN
cord-342419-liaihahj	232	15	ketone)-trypsin	ketone)-trypsin	NNP
cord-342419-liaihahj	233	1	(	(	-LRB-
cord-342419-liaihahj	233	2	Thermo	Thermo	NNP
cord-342419-liaihahj	233	3	Scientific	Scientific	NNP
cord-342419-liaihahj	233	4	)	)	-RRB-
cord-342419-liaihahj	233	5	was	be	VBD
cord-342419-liaihahj	233	6	dissolved	dissolve	VBN
cord-342419-liaihahj	233	7	in	in	IN
cord-342419-liaihahj	233	8	double	double	JJ
cord-342419-liaihahj	233	9	-	-	HYPH
cord-342419-liaihahj	233	10	distilled	distilled	JJ
cord-342419-liaihahj	233	11	water	water	NN
cord-342419-liaihahj	233	12	(	(	-LRB-
cord-342419-liaihahj	233	13	ddH	ddh	JJ
cord-342419-liaihahj	233	14	2	2	CD
cord-342419-liaihahj	233	15	O	o	NN
cord-342419-liaihahj	233	16	)	)	-RRB-
cord-342419-liaihahj	233	17	at	at	IN
cord-342419-liaihahj	233	18	2	2	CD
cord-342419-liaihahj	233	19	mg/	mg/	NN
cord-342419-liaihahj	234	1	mL.	mL.	NNS
cord-342419-liaihahj	234	2	Purified	purify	VBN
cord-342419-liaihahj	235	1	hMPV	hMPV	NNP
cord-342419-liaihahj	235	2	B2	B2	NNP
cord-342419-liaihahj	235	3	F	F	NNP
cord-342419-liaihahj	235	4	was	be	VBD
cord-342419-liaihahj	235	5	incubated	incubate	VBN
cord-342419-liaihahj	235	6	with	with	IN
cord-342419-liaihahj	235	7	5	5	CD
cord-342419-liaihahj	235	8	TAME	tame	JJ
cord-342419-liaihahj	235	9	(	(	-LRB-
cord-342419-liaihahj	235	10	p	p	NN
cord-342419-liaihahj	235	11	-	-	HYPH
cord-342419-liaihahj	235	12	toluene	toluene	NN
cord-342419-liaihahj	235	13	-	-	HYPH
cord-342419-liaihahj	235	14	sulfonyl	sulfonyl	NN
cord-342419-liaihahj	235	15	-	-	HYPH
cord-342419-liaihahj	235	16	L	l	NN
cord-342419-liaihahj	235	17	-	-	HYPH
cord-342419-liaihahj	235	18	arginine	arginine	NN
cord-342419-liaihahj	236	1	methyl	methyl	NNP
cord-342419-liaihahj	236	2	ester	ester	NNP
cord-342419-liaihahj	236	3	)	)	-RRB-
cord-342419-liaihahj	236	4	units	unit	NNS
cord-342419-liaihahj	236	5	/	/	SYM
cord-342419-liaihahj	236	6	mg	mg	NN
cord-342419-liaihahj	236	7	of	of	IN
cord-342419-liaihahj	236	8	TPCK	TPCK	NNP
cord-342419-liaihahj	236	9	-	-	HYPH
cord-342419-liaihahj	236	10	trypsin	trypsin	NN
cord-342419-liaihahj	236	11	for	for	IN
cord-342419-liaihahj	236	12	1	1	CD
cord-342419-liaihahj	236	13	hr	hr	NN
cord-342419-liaihahj	236	14	at	at	IN
cord-342419-liaihahj	236	15	37˚C.	37˚c.	CD
cord-342419-liaihahj	237	1	Trimeric	Trimeric	NNP
cord-342419-liaihahj	237	2	and	and	CC
cord-342419-liaihahj	237	3	monomeric	monomeric	JJ
cord-342419-liaihahj	237	4	hMPV	hmpv	NN
cord-342419-liaihahj	237	5	B2	b2	NN
cord-342419-liaihahj	237	6	F	F	NNP
cord-342419-liaihahj	237	7	proteins	protein	NNS
cord-342419-liaihahj	237	8	were	be	VBD
cord-342419-liaihahj	237	9	purified	purify	VBN
cord-342419-liaihahj	237	10	from	from	IN
cord-342419-liaihahj	237	11	the	the	DT
cord-342419-liaihahj	237	12	digestion	digestion	NN
cord-342419-liaihahj	237	13	reaction	reaction	NN
cord-342419-liaihahj	237	14	mixture	mixture	NN
cord-342419-liaihahj	237	15	by	by	IN
cord-342419-liaihahj	237	16	size	size	NN
cord-342419-liaihahj	237	17	exclusion	exclusion	NN
cord-342419-liaihahj	237	18	chromatography	chromatography	NN
cord-342419-liaihahj	237	19	on	on	IN
cord-342419-liaihahj	237	20	a	a	DT
cord-342419-liaihahj	237	21	Superdex	Superdex	NNP
cord-342419-liaihahj	237	22	S200	s200	NN
cord-342419-liaihahj	237	23	,	,	,
cord-342419-liaihahj	237	24	16/600	16/600	CD
cord-342419-liaihahj	237	25	column	column	NN
cord-342419-liaihahj	237	26	(	(	-LRB-
cord-342419-liaihahj	237	27	GE	GE	NNP
cord-342419-liaihahj	237	28	Healthcare	Healthcare	NNP
cord-342419-liaihahj	237	29	Life	Life	NNP
cord-342419-liaihahj	237	30	Sciences	Sciences	NNPS
cord-342419-liaihahj	237	31	)	)	-RRB-
cord-342419-liaihahj	237	32	in	in	IN
cord-342419-liaihahj	237	33	column	column	NN
cord-342419-liaihahj	237	34	buffer	buffer	NN
cord-342419-liaihahj	237	35	(	(	-LRB-
cord-342419-liaihahj	237	36	50	50	CD
cord-342419-liaihahj	237	37	mM	mm	CD
cord-342419-liaihahj	237	38	Tris	Tris	NNP
cord-342419-liaihahj	237	39	pH	pH	NNP
cord-342419-liaihahj	237	40	7.5	7.5	CD
cord-342419-liaihahj	237	41	,	,	,
cord-342419-liaihahj	237	42	and	and	CC
cord-342419-liaihahj	237	43	100	100	CD
cord-342419-liaihahj	237	44	mM	mm	CD
cord-342419-liaihahj	237	45	NaCl	nacl	NN
cord-342419-liaihahj	237	46	)	)	-RRB-
cord-342419-liaihahj	237	47	.	.	.
cord-342419-liaihahj	238	1	Trimeric	Trimeric	NNP
cord-342419-liaihahj	238	2	hMPV	hmpv	NN
cord-342419-liaihahj	239	1	B2	B2	NNP
cord-342419-liaihahj	239	2	F	F	NNP
cord-342419-liaihahj	239	3	protein	protein	NN
cord-342419-liaihahj	239	4	was	be	VBD
cord-342419-liaihahj	239	5	identified	identify	VBN
cord-342419-liaihahj	239	6	by	by	IN
cord-342419-liaihahj	239	7	a	a	DT
cord-342419-liaihahj	239	8	shift	shift	NN
cord-342419-liaihahj	239	9	in	in	IN
cord-342419-liaihahj	239	10	the	the	DT
cord-342419-liaihahj	239	11	elution	elution	NN
cord-342419-liaihahj	239	12	profile	profile	NN
cord-342419-liaihahj	239	13	from	from	IN
cord-342419-liaihahj	239	14	monomeric	monomeric	JJ
cord-342419-liaihahj	239	15	hMPV	hmpv	NN
cord-342419-liaihahj	239	16	B2	b2	NN
cord-342419-liaihahj	239	17	F	F	NNP
cord-342419-liaihahj	239	18	protein	protein	NN
cord-342419-liaihahj	239	19	.	.	.
cord-342419-liaihahj	240	1	The	the	DT
cord-342419-liaihahj	240	2	fractions	fraction	NNS
cord-342419-liaihahj	240	3	containing	contain	VBG
cord-342419-liaihahj	240	4	the	the	DT
cord-342419-liaihahj	240	5	trimers	trimer	NNS
cord-342419-liaihahj	240	6	and	and	CC
cord-342419-liaihahj	240	7	monomers	monomer	NNS
cord-342419-liaihahj	240	8	were	be	VBD
cord-342419-liaihahj	240	9	concentrated	concentrate	VBN
cord-342419-liaihahj	240	10	using	use	VBG
cord-342419-liaihahj	240	11	30-kDa	30-kda	CD
cord-342419-liaihahj	241	1	Spin	spin	NN
cord-342419-liaihahj	241	2	-	-	HYPH
cord-342419-liaihahj	241	3	X	x	NN
cord-342419-liaihahj	241	4	UF	UF	NNP
cord-342419-liaihahj	241	5	concentrators	concentrator	NNS
cord-342419-liaihahj	241	6	(	(	-LRB-
cord-342419-liaihahj	241	7	Corning	Corning	NNP
cord-342419-liaihahj	241	8	)	)	-RRB-
cord-342419-liaihahj	241	9	.	.	.
cord-342419-liaihahj	242	1	To	to	TO
cord-342419-liaihahj	242	2	obtain	obtain	VB
cord-342419-liaihahj	242	3	fully	fully	RB
cord-342419-liaihahj	242	4	post	post	JJ
cord-342419-liaihahj	242	5	-	-	JJ
cord-342419-liaihahj	242	6	fusion	fusion	JJ
cord-342419-liaihahj	242	7	hMPV	hmpv	NN
cord-342419-liaihahj	242	8	F	F	NNP
cord-342419-liaihahj	242	9	,	,	,
cord-342419-liaihahj	242	10	samples	sample	NNS
cord-342419-liaihahj	242	11	were	be	VBD
cord-342419-liaihahj	242	12	heated	heat	VBN
cord-342419-liaihahj	242	13	at	at	IN
cord-342419-liaihahj	242	14	55˚C	55˚c	CD
cord-342419-liaihahj	242	15	for	for	IN
cord-342419-liaihahj	242	16	20	20	CD
cord-342419-liaihahj	242	17	minutes	minute	NNS
cord-342419-liaihahj	242	18	to	to	TO
cord-342419-liaihahj	242	19	induce	induce	VB
cord-342419-liaihahj	242	20	conversion	conversion	NN
cord-342419-liaihahj	242	21	of	of	IN
cord-342419-liaihahj	242	22	remaining	remain	VBG
cord-342419-liaihahj	242	23	pre	pre	JJ
cord-342419-liaihahj	242	24	-	-	JJ
cord-342419-liaihahj	242	25	fusion	fusion	JJ
cord-342419-liaihahj	242	26	hMPV	hmpv	NN
cord-342419-liaihahj	242	27	F	F	NNP
cord-342419-liaihahj	242	28	proteins	protein	NNS
cord-342419-liaihahj	242	29	to	to	IN
cord-342419-liaihahj	242	30	the	the	DT
cord-342419-liaihahj	242	31	post	post	JJ
cord-342419-liaihahj	242	32	-	-	JJ
cord-342419-liaihahj	242	33	fusion	fusion	JJ
cord-342419-liaihahj	242	34	conformation	conformation	NN
cord-342419-liaihahj	242	35	.	.	.
cord-342419-liaihahj	243	1	All	all	DT
cord-342419-liaihahj	243	2	samples	sample	NNS
cord-342419-liaihahj	243	3	were	be	VBD
cord-342419-liaihahj	243	4	purified	purify	VBN
cord-342419-liaihahj	243	5	by	by	IN
cord-342419-liaihahj	243	6	size	size	NN
cord-342419-liaihahj	243	7	exclusion	exclusion	NN
cord-342419-liaihahj	243	8	chromatography	chromatography	NN
cord-342419-liaihahj	243	9	on	on	IN
cord-342419-liaihahj	243	10	a	a	DT
cord-342419-liaihahj	243	11	Superdex	Superdex	NNP
cord-342419-liaihahj	243	12	S200	s200	NN
cord-342419-liaihahj	243	13	,	,	,
cord-342419-liaihahj	243	14	16/600	16/600	CD
cord-342419-liaihahj	243	15	column	column	NN
cord-342419-liaihahj	243	16	(	(	-LRB-
cord-342419-liaihahj	243	17	GE	GE	NNP
cord-342419-liaihahj	243	18	Healthcare	Healthcare	NNP
cord-342419-liaihahj	243	19	Life	Life	NNP
cord-342419-liaihahj	243	20	Sciences	Sciences	NNPS
cord-342419-liaihahj	243	21	)	)	-RRB-
cord-342419-liaihahj	243	22	in	in	IN
cord-342419-liaihahj	243	23	column	column	NN
cord-342419-liaihahj	243	24	buffer	buffer	NN
cord-342419-liaihahj	243	25	before	before	IN
cord-342419-liaihahj	243	26	they	-PRON-	PRP
cord-342419-liaihahj	243	27	were	be	VBD
cord-342419-liaihahj	243	28	applied	apply	VBN
cord-342419-liaihahj	243	29	on	on	IN
cord-342419-liaihahj	243	30	grids	grid	NNS
cord-342419-liaihahj	243	31	.	.	.
cord-342419-liaihahj	244	1	Carbon	carbon	NN
cord-342419-liaihahj	244	2	-	-	HYPH
cord-342419-liaihahj	244	3	coated	coat	VBN
cord-342419-liaihahj	244	4	copper	copper	NN
cord-342419-liaihahj	244	5	grids	grid	NNS
cord-342419-liaihahj	244	6	(	(	-LRB-
cord-342419-liaihahj	244	7	Electron	Electron	NNP
cord-342419-liaihahj	244	8	Microscopy	Microscopy	NNP
cord-342419-liaihahj	244	9	Sciences	Sciences	NNPS
cord-342419-liaihahj	244	10	)	)	-RRB-
cord-342419-liaihahj	244	11	were	be	VBD
cord-342419-liaihahj	244	12	overlaid	overlay	VBN
cord-342419-liaihahj	244	13	with	with	IN
cord-342419-liaihahj	244	14	5	5	CD
cord-342419-liaihahj	244	15	μl	μl	NN
cord-342419-liaihahj	244	16	of	of	IN
cord-342419-liaihahj	244	17	protein	protein	NN
cord-342419-liaihahj	244	18	solutions	solution	NNS
cord-342419-liaihahj	244	19	(	(	-LRB-
cord-342419-liaihahj	244	20	10	10	CD
cord-342419-liaihahj	244	21	μg	μg	NN
cord-342419-liaihahj	244	22	/	/	SYM
cord-342419-liaihahj	244	23	mL	mL	NNP
cord-342419-liaihahj	244	24	)	)	-RRB-
cord-342419-liaihahj	244	25	for	for	IN
cord-342419-liaihahj	244	26	3	3	CD
cord-342419-liaihahj	244	27	min	min	NN
cord-342419-liaihahj	244	28	.	.	.
cord-342419-liaihahj	245	1	The	the	DT
cord-342419-liaihahj	245	2	grid	grid	NN
cord-342419-liaihahj	245	3	was	be	VBD
cord-342419-liaihahj	245	4	washed	wash	VBN
cord-342419-liaihahj	245	5	in	in	IN
cord-342419-liaihahj	245	6	water	water	NN
cord-342419-liaihahj	245	7	twice	twice	RB
cord-342419-liaihahj	245	8	and	and	CC
cord-342419-liaihahj	245	9	then	then	RB
cord-342419-liaihahj	245	10	stained	stain	VBN
cord-342419-liaihahj	245	11	with	with	IN
cord-342419-liaihahj	245	12	0.75	0.75	CD
cord-342419-liaihahj	245	13	%	%	NN
cord-342419-liaihahj	245	14	uranyl	uranyl	NN
cord-342419-liaihahj	245	15	formate	formate	NN
cord-342419-liaihahj	245	16	for	for	IN
cord-342419-liaihahj	245	17	1	1	CD
cord-342419-liaihahj	245	18	min	min	NN
cord-342419-liaihahj	245	19	.	.	.
cord-342419-liaihahj	246	1	Negative	negative	JJ
cord-342419-liaihahj	246	2	-	-	HYPH
cord-342419-liaihahj	246	3	stain	stain	NN
cord-342419-liaihahj	246	4	electron	electron	NN
cord-342419-liaihahj	246	5	micrographs	micrograph	NNS
cord-342419-liaihahj	246	6	were	be	VBD
cord-342419-liaihahj	246	7	acquired	acquire	VBN
cord-342419-liaihahj	246	8	using	use	VBG
cord-342419-liaihahj	246	9	a	a	DT
cord-342419-liaihahj	246	10	Antibody	Antibody	NNP
cord-342419-liaihahj	246	11	recognition	recognition	NN
cord-342419-liaihahj	246	12	of	of	IN
cord-342419-liaihahj	246	13	the	the	DT
cord-342419-liaihahj	246	14	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	246	15	fusion	fusion	NN
cord-342419-liaihahj	246	16	protein	protein	NN
cord-342419-liaihahj	246	17	trimer	trimer	NN
cord-342419-liaihahj	246	18	interface	interface	NN
cord-342419-liaihahj	246	19	JEOL	JEOL	NNP
cord-342419-liaihahj	247	1	JEM1011	JEM1011	NNP
cord-342419-liaihahj	247	2	transmission	transmission	NN
cord-342419-liaihahj	247	3	electron	electron	NN
cord-342419-liaihahj	247	4	microscope	microscope	NN
cord-342419-liaihahj	247	5	equipped	equip	VBN
cord-342419-liaihahj	247	6	with	with	IN
cord-342419-liaihahj	247	7	a	a	DT
cord-342419-liaihahj	247	8	high	high	JJ
cord-342419-liaihahj	247	9	-	-	HYPH
cord-342419-liaihahj	247	10	contrast	contrast	NN
cord-342419-liaihahj	247	11	2K	2k	NN
cord-342419-liaihahj	247	12	-	-	HYPH
cord-342419-liaihahj	247	13	by-2	by-2	NN
cord-342419-liaihahj	247	14	K	K	NNP
cord-342419-liaihahj	247	15	AMT	AMT	NNP
cord-342419-liaihahj	247	16	midmount	midmount	NN
cord-342419-liaihahj	247	17	digital	digital	JJ
cord-342419-liaihahj	247	18	camera	camera	NN
cord-342419-liaihahj	247	19	.	.	.
cord-342419-liaihahj	248	1	For	for	IN
cord-342419-liaihahj	248	2	hybridoma	hybridoma	NN
cord-342419-liaihahj	248	3	generation	generation	NN
cord-342419-liaihahj	248	4	,	,	,
cord-342419-liaihahj	248	5	10	10	CD
cord-342419-liaihahj	248	6	million	million	CD
cord-342419-liaihahj	248	7	peripheral	peripheral	JJ
cord-342419-liaihahj	248	8	blood	blood	NN
cord-342419-liaihahj	248	9	mononuclear	mononuclear	NN
cord-342419-liaihahj	248	10	cells	cell	NNS
cord-342419-liaihahj	248	11	purified	purify	VBN
cord-342419-liaihahj	248	12	from	from	IN
cord-342419-liaihahj	248	13	the	the	DT
cord-342419-liaihahj	248	14	blood	blood	NN
cord-342419-liaihahj	248	15	of	of	IN
cord-342419-liaihahj	248	16	human	human	JJ
cord-342419-liaihahj	248	17	donors	donor	NNS
cord-342419-liaihahj	248	18	were	be	VBD
cord-342419-liaihahj	248	19	mixed	mix	VBN
cord-342419-liaihahj	248	20	with	with	IN
cord-342419-liaihahj	248	21	8	8	CD
cord-342419-liaihahj	248	22	million	million	CD
cord-342419-liaihahj	248	23	previously	previously	RB
cord-342419-liaihahj	248	24	frozen	freeze	VBN
cord-342419-liaihahj	248	25	and	and	CC
cord-342419-liaihahj	249	1	gamma	gamma	NNP
cord-342419-liaihahj	249	2	irradiated	irradiate	VBD
cord-342419-liaihahj	249	3	NIH	NIH	NNP
cord-342419-liaihahj	249	4	3T3	3t3	CD
cord-342419-liaihahj	249	5	cells	cell	NNS
cord-342419-liaihahj	249	6	modified	modify	VBN
cord-342419-liaihahj	249	7	to	to	TO
cord-342419-liaihahj	249	8	express	express	VB
cord-342419-liaihahj	249	9	human	human	NN
cord-342419-liaihahj	249	10	CD40L	cd40l	NN
cord-342419-liaihahj	249	11	,	,	,
cord-342419-liaihahj	249	12	human	human	JJ
cord-342419-liaihahj	249	13	interleukin-21	interleukin-21	NN
cord-342419-liaihahj	249	14	(	(	-LRB-
cord-342419-liaihahj	249	15	IL-21	IL-21	NNP
cord-342419-liaihahj	249	16	)	)	-RRB-
cord-342419-liaihahj	249	17	,	,	,
cord-342419-liaihahj	249	18	and	and	CC
cord-342419-liaihahj	249	19	human	human	JJ
cord-342419-liaihahj	249	20	BAFF	BAFF	NNP
cord-342419-liaihahj	249	21	[	[	-LRB-
cord-342419-liaihahj	249	22	54	54	CD
cord-342419-liaihahj	249	23	]	]	-RRB-
cord-342419-liaihahj	249	24	in	in	IN
cord-342419-liaihahj	249	25	80	80	CD
cord-342419-liaihahj	249	26	mL	ml	NN
cord-342419-liaihahj	249	27	StemCell	StemCell	NNP
cord-342419-liaihahj	249	28	medium	medium	NN
cord-342419-liaihahj	249	29	A	a	NN
cord-342419-liaihahj	249	30	(	(	-LRB-
cord-342419-liaihahj	249	31	StemCell	StemCell	NNP
cord-342419-liaihahj	249	32	Technologies	Technologies	NNPS
cord-342419-liaihahj	249	33	)	)	-RRB-
cord-342419-liaihahj	249	34	containing	contain	VBG
cord-342419-liaihahj	249	35	6.3	6.3	CD
cord-342419-liaihahj	249	36	μg	μg	NN
cord-342419-liaihahj	249	37	/	/	SYM
cord-342419-liaihahj	249	38	mL	mL	NNP
cord-342419-liaihahj	249	39	of	of	IN
cord-342419-liaihahj	249	40	CpG	CpG	NNP
cord-342419-liaihahj	249	41	(	(	-LRB-
cord-342419-liaihahj	249	42	phosphorothioate	phosphorothioate	NN
cord-342419-liaihahj	249	43	-	-	HYPH
cord-342419-liaihahj	249	44	modified	modify	VBN
cord-342419-liaihahj	249	45	oligodeoxynucleotide	oligodeoxynucleotide	NN
cord-342419-liaihahj	249	46	ZOEZOEZZZZZOEEZOEZZZT	ZOEZOEZZZZZOEEZOEZZZT	NNP
cord-342419-liaihahj	249	47	;	;	:
cord-342419-liaihahj	249	48	Invitrogen	Invitrogen	NNP
cord-342419-liaihahj	249	49	)	)	-RRB-
cord-342419-liaihahj	249	50	and	and	CC
cord-342419-liaihahj	249	51	1	1	CD
cord-342419-liaihahj	249	52	μg	μg	NN
cord-342419-liaihahj	249	53	/	/	SYM
cord-342419-liaihahj	249	54	mL	mL	NNP
cord-342419-liaihahj	249	55	of	of	IN
cord-342419-liaihahj	249	56	cyclosporine	cyclosporine	NN
cord-342419-liaihahj	249	57	A	a	NN
cord-342419-liaihahj	250	1	(	(	-LRB-
cord-342419-liaihahj	250	2	Millipore	Millipore	NNP
cord-342419-liaihahj	250	3	-	-	HYPH
cord-342419-liaihahj	250	4	Sigma	Sigma	NNP
cord-342419-liaihahj	250	5	)	)	-RRB-
cord-342419-liaihahj	250	6	.	.	.
cord-342419-liaihahj	251	1	The	the	DT
cord-342419-liaihahj	251	2	mixture	mixture	NN
cord-342419-liaihahj	251	3	of	of	IN
cord-342419-liaihahj	251	4	cells	cell	NNS
cord-342419-liaihahj	251	5	was	be	VBD
cord-342419-liaihahj	251	6	plated	plate	VBN
cord-342419-liaihahj	251	7	in	in	IN
cord-342419-liaihahj	251	8	four	four	CD
cord-342419-liaihahj	251	9	96-well	96-well	CD
cord-342419-liaihahj	251	10	plates	plate	NNS
cord-342419-liaihahj	251	11	at	at	IN
cord-342419-liaihahj	251	12	200	200	CD
cord-342419-liaihahj	251	13	μl	μl	XX
cord-342419-liaihahj	251	14	per	per	RB
cord-342419-liaihahj	251	15	well	well	RB
cord-342419-liaihahj	251	16	in	in	IN
cord-342419-liaihahj	251	17	StemCell	StemCell	NNP
cord-342419-liaihahj	251	18	medium	medium	NN
cord-342419-liaihahj	251	19	A.	a.	NN
cord-342419-liaihahj	252	1	After	after	IN
cord-342419-liaihahj	252	2	6	6	CD
cord-342419-liaihahj	252	3	days	day	NNS
cord-342419-liaihahj	252	4	,	,	,
cord-342419-liaihahj	252	5	culture	culture	NN
cord-342419-liaihahj	252	6	supernatants	supernatant	NNS
cord-342419-liaihahj	252	7	were	be	VBD
cord-342419-liaihahj	252	8	screened	screen	VBN
cord-342419-liaihahj	252	9	by	by	IN
cord-342419-liaihahj	252	10	ELISA	ELISA	NNP
cord-342419-liaihahj	252	11	for	for	IN
cord-342419-liaihahj	252	12	binding	bind	VBG
cord-342419-liaihahj	252	13	to	to	IN
cord-342419-liaihahj	252	14	recombinant	recombinant	JJ
cord-342419-liaihahj	252	15	hMPV	hmpv	NN
cord-342419-liaihahj	252	16	B2	b2	NN
cord-342419-liaihahj	252	17	F	F	NNP
cord-342419-liaihahj	252	18	protein	protein	NN
cord-342419-liaihahj	252	19	,	,	,
cord-342419-liaihahj	252	20	and	and	CC
cord-342419-liaihahj	252	21	cells	cell	NNS
cord-342419-liaihahj	252	22	from	from	IN
cord-342419-liaihahj	252	23	positive	positive	JJ
cord-342419-liaihahj	252	24	wells	well	NNS
cord-342419-liaihahj	252	25	were	be	VBD
cord-342419-liaihahj	252	26	electrofused	electrofuse	VBN
cord-342419-liaihahj	252	27	as	as	IN
cord-342419-liaihahj	252	28	previously	previously	RB
cord-342419-liaihahj	252	29	described	describe	VBN
cord-342419-liaihahj	252	30	[	[	-LRB-
cord-342419-liaihahj	252	31	54	54	CD
cord-342419-liaihahj	252	32	]	]	-RRB-
cord-342419-liaihahj	252	33	.	.	.
cord-342419-liaihahj	253	1	Cells	cell	NNS
cord-342419-liaihahj	253	2	from	from	IN
cord-342419-liaihahj	253	3	each	each	DT
cord-342419-liaihahj	253	4	cuvette	cuvette	NN
cord-342419-liaihahj	253	5	were	be	VBD
cord-342419-liaihahj	253	6	resuspended	resuspend	VBN
cord-342419-liaihahj	253	7	in	in	IN
cord-342419-liaihahj	253	8	20	20	CD
cord-342419-liaihahj	253	9	mL	ml	NN
cord-342419-liaihahj	253	10	StemCell	StemCell	NNP
cord-342419-liaihahj	253	11	medium	medium	NN
cord-342419-liaihahj	253	12	A	a	NN
cord-342419-liaihahj	253	13	containing	contain	VBG
cord-342419-liaihahj	253	14	1×	1×	CD
cord-342419-liaihahj	253	15	HAT	hat	NN
cord-342419-liaihahj	253	16	(	(	-LRB-
cord-342419-liaihahj	253	17	hypoxanthine	hypoxanthine	JJ
cord-342419-liaihahj	253	18	-	-	HYPH
cord-342419-liaihahj	253	19	aminopterinthymidine	aminopterinthymidine	NNP
cord-342419-liaihahj	253	20	;	;	:
cord-342419-liaihahj	253	21	Sigma	Sigma	NNP
cord-342419-liaihahj	253	22	-	-	HYPH
cord-342419-liaihahj	253	23	Aldrich	Aldrich	NNP
cord-342419-liaihahj	253	24	)	)	-RRB-
cord-342419-liaihahj	253	25	,	,	,
cord-342419-liaihahj	253	26	0.2×	0.2×	CD
cord-342419-liaihahj	254	1	HT	HT	NNP
cord-342419-liaihahj	254	2	(	(	-LRB-
cord-342419-liaihahj	254	3	hypoxanthine	hypoxanthine	NN
cord-342419-liaihahj	254	4	-	-	HYPH
cord-342419-liaihahj	254	5	thymidine	thymidine	NN
cord-342419-liaihahj	254	6	;	;	:
cord-342419-liaihahj	254	7	Corning	Corning	NNP
cord-342419-liaihahj	254	8	)	)	-RRB-
cord-342419-liaihahj	254	9	,	,	,
cord-342419-liaihahj	254	10	and	and	CC
cord-342419-liaihahj	254	11	0.3	0.3	CD
cord-342419-liaihahj	254	12	μg	μg	NN
cord-342419-liaihahj	254	13	/	/	SYM
cord-342419-liaihahj	254	14	mL	ml	NN
cord-342419-liaihahj	254	15	ouabain	ouabain	NN
cord-342419-liaihahj	254	16	(	(	-LRB-
cord-342419-liaihahj	254	17	Thermo	Thermo	NNP
cord-342419-liaihahj	254	18	Fisher	Fisher	NNP
cord-342419-liaihahj	254	19	Scientific	Scientific	NNP
cord-342419-liaihahj	254	20	)	)	-RRB-
cord-342419-liaihahj	254	21	and	and	CC
cord-342419-liaihahj	254	22	plated	plate	VBN
cord-342419-liaihahj	254	23	at	at	IN
cord-342419-liaihahj	254	24	50	50	CD
cord-342419-liaihahj	254	25	μl	μl	UH
cord-342419-liaihahj	254	26	per	per	RB
cord-342419-liaihahj	254	27	well	well	RB
cord-342419-liaihahj	254	28	in	in	IN
cord-342419-liaihahj	254	29	a	a	DT
cord-342419-liaihahj	254	30	384-well	384-well	CD
cord-342419-liaihahj	254	31	plate	plate	NN
cord-342419-liaihahj	254	32	.	.	.
cord-342419-liaihahj	255	1	After	after	IN
cord-342419-liaihahj	255	2	7	7	CD
cord-342419-liaihahj	255	3	days	day	NNS
cord-342419-liaihahj	255	4	,	,	,
cord-342419-liaihahj	255	5	cells	cell	NNS
cord-342419-liaihahj	255	6	were	be	VBD
cord-342419-liaihahj	255	7	fed	feed	VBN
cord-342419-liaihahj	255	8	with	with	IN
cord-342419-liaihahj	255	9	25	25	CD
cord-342419-liaihahj	255	10	μl	μl	NN
cord-342419-liaihahj	255	11	of	of	IN
cord-342419-liaihahj	255	12	StemCell	StemCell	NNP
cord-342419-liaihahj	255	13	medium	medium	NN
cord-342419-liaihahj	255	14	A.	a.	NN
cord-342419-liaihahj	256	1	The	the	DT
cord-342419-liaihahj	256	2	supernatant	supernatant	NN
cord-342419-liaihahj	256	3	of	of	IN
cord-342419-liaihahj	256	4	hybridomas	hybridomas	NNP
cord-342419-liaihahj	256	5	were	be	VBD
cord-342419-liaihahj	256	6	screened	screen	VBN
cord-342419-liaihahj	256	7	after	after	IN
cord-342419-liaihahj	256	8	2	2	CD
cord-342419-liaihahj	256	9	weeks	week	NNS
cord-342419-liaihahj	256	10	for	for	IN
cord-342419-liaihahj	256	11	antibody	antibody	NN
cord-342419-liaihahj	256	12	production	production	NN
cord-342419-liaihahj	256	13	by	by	IN
cord-342419-liaihahj	256	14	ELISA	ELISA	NNP
cord-342419-liaihahj	256	15	,	,	,
cord-342419-liaihahj	256	16	and	and	CC
cord-342419-liaihahj	256	17	cells	cell	NNS
cord-342419-liaihahj	256	18	from	from	IN
cord-342419-liaihahj	256	19	wells	well	NNS
cord-342419-liaihahj	256	20	with	with	IN
cord-342419-liaihahj	256	21	reactive	reactive	JJ
cord-342419-liaihahj	256	22	supernatants	supernatant	NNS
cord-342419-liaihahj	256	23	were	be	VBD
cord-342419-liaihahj	256	24	expanded	expand	VBN
cord-342419-liaihahj	256	25	to	to	IN
cord-342419-liaihahj	256	26	48-well	48-well	CD
cord-342419-liaihahj	256	27	plates	plate	NNS
cord-342419-liaihahj	256	28	for	for	IN
cord-342419-liaihahj	256	29	1	1	CD
cord-342419-liaihahj	256	30	week	week	NN
cord-342419-liaihahj	256	31	in	in	IN
cord-342419-liaihahj	256	32	0.5	0.5	CD
cord-342419-liaihahj	256	33	mL	ml	NN
cord-342419-liaihahj	256	34	of	of	IN
cord-342419-liaihahj	256	35	StemCell	StemCell	NNP
cord-342419-liaihahj	256	36	medium	medium	NN
cord-342419-liaihahj	256	37	E	e	NN
cord-342419-liaihahj	256	38	(	(	-LRB-
cord-342419-liaihahj	256	39	StemCell	StemCell	NNP
cord-342419-liaihahj	256	40	Technologies	Technologies	NNPS
cord-342419-liaihahj	256	41	)	)	-RRB-
cord-342419-liaihahj	256	42	,	,	,
cord-342419-liaihahj	256	43	before	before	IN
cord-342419-liaihahj	256	44	being	be	VBG
cord-342419-liaihahj	256	45	screened	screen	VBN
cord-342419-liaihahj	256	46	again	again	RB
cord-342419-liaihahj	256	47	by	by	IN
cord-342419-liaihahj	256	48	ELISA	ELISA	NNP
cord-342419-liaihahj	256	49	.	.	.
cord-342419-liaihahj	257	1	Positive	positive	JJ
cord-342419-liaihahj	257	2	hybridomas	hybridomas	NN
cord-342419-liaihahj	257	3	were	be	VBD
cord-342419-liaihahj	257	4	then	then	RB
cord-342419-liaihahj	257	5	subjected	subject	VBN
cord-342419-liaihahj	257	6	to	to	IN
cord-342419-liaihahj	257	7	single	single	JJ
cord-342419-liaihahj	257	8	-	-	HYPH
cord-342419-liaihahj	257	9	cell	cell	NN
cord-342419-liaihahj	257	10	fluorescence	fluorescence	NN
cord-342419-liaihahj	257	11	-	-	HYPH
cord-342419-liaihahj	257	12	activated	activate	VBN
cord-342419-liaihahj	257	13	sorting	sorting	NN
cord-342419-liaihahj	257	14	into	into	IN
cord-342419-liaihahj	257	15	384-well	384-well	CD
cord-342419-liaihahj	257	16	plates	plate	NNS
cord-342419-liaihahj	257	17	containing	contain	VBG
cord-342419-liaihahj	257	18	75	75	CD
cord-342419-liaihahj	257	19	%	%	NN
cord-342419-liaihahj	257	20	of	of	IN
cord-342419-liaihahj	257	21	StemCell	StemCell	NNP
cord-342419-liaihahj	257	22	medium	medium	NN
cord-342419-liaihahj	257	23	A	a	NN
cord-342419-liaihahj	257	24	plus	plus	CC
cord-342419-liaihahj	257	25	25	25	CD
cord-342419-liaihahj	257	26	%	%	NN
cord-342419-liaihahj	257	27	of	of	IN
cord-342419-liaihahj	257	28	StemCell	StemCell	NNP
cord-342419-liaihahj	257	29	medium	medium	NN
cord-342419-liaihahj	257	30	E.	E.	NNP
cord-342419-liaihahj	257	31	Two	two	CD
cord-342419-liaihahj	257	32	weeks	week	NNS
cord-342419-liaihahj	257	33	after	after	IN
cord-342419-liaihahj	257	34	cell	cell	NN
cord-342419-liaihahj	257	35	sorting	sorting	NN
cord-342419-liaihahj	257	36	,	,	,
cord-342419-liaihahj	257	37	hybridomas	hybridomas	NNP
cord-342419-liaihahj	257	38	were	be	VBD
cord-342419-liaihahj	257	39	screened	screen	VBN
cord-342419-liaihahj	257	40	by	by	IN
cord-342419-liaihahj	257	41	ELISA	ELISA	NNP
cord-342419-liaihahj	257	42	before	before	IN
cord-342419-liaihahj	257	43	further	further	JJ
cord-342419-liaihahj	257	44	expansion	expansion	NN
cord-342419-liaihahj	257	45	of	of	IN
cord-342419-liaihahj	257	46	wells	well	NNS
cord-342419-liaihahj	257	47	containing	contain	VBG
cord-342419-liaihahj	257	48	hMPV	hMPV	NNP
cord-342419-liaihahj	257	49	F	F	NNP
cord-342419-liaihahj	257	50	-	-	HYPH
cord-342419-liaihahj	257	51	specific	specific	JJ
cord-342419-liaihahj	257	52	hybridomas	hybridomas	NN
cord-342419-liaihahj	257	53	.	.	.
cord-342419-liaihahj	258	1	For	for	IN
cord-342419-liaihahj	258	2	recombinant	recombinant	JJ
cord-342419-liaihahj	258	3	mAbs	mAbs	NNP
cord-342419-liaihahj	258	4	,	,	,
cord-342419-liaihahj	258	5	plasmids	plasmid	NNS
cord-342419-liaihahj	258	6	encoding	encode	VBG
cord-342419-liaihahj	258	7	cDNAs	cdna	NNS
cord-342419-liaihahj	258	8	for	for	IN
cord-342419-liaihahj	258	9	the	the	DT
cord-342419-liaihahj	258	10	heavy	heavy	JJ
cord-342419-liaihahj	258	11	and	and	CC
cord-342419-liaihahj	258	12	light	light	JJ
cord-342419-liaihahj	258	13	chain	chain	NN
cord-342419-liaihahj	258	14	sequences	sequence	NNS
cord-342419-liaihahj	258	15	of	of	IN
cord-342419-liaihahj	258	16	101F	101f	CD
cord-342419-liaihahj	258	17	[	[	-LRB-
cord-342419-liaihahj	258	18	70	70	CD
cord-342419-liaihahj	258	19	]	]	-RRB-
cord-342419-liaihahj	258	20	,	,	,
cord-342419-liaihahj	258	21	MPE8	MPE8	NNP
cord-342419-liaihahj	258	22	[	[	-LRB-
cord-342419-liaihahj	258	23	51	51	CD
cord-342419-liaihahj	258	24	]	]	-RRB-
cord-342419-liaihahj	258	25	,	,	,
cord-342419-liaihahj	258	26	and	and	CC
cord-342419-liaihahj	258	27	DS7	ds7	VBP
cord-342419-liaihahj	258	28	[	[	-LRB-
cord-342419-liaihahj	258	29	49	49	CD
cord-342419-liaihahj	258	30	]	]	-RRB-
cord-342419-liaihahj	258	31	were	be	VBD
cord-342419-liaihahj	258	32	synthesized	synthesize	VBN
cord-342419-liaihahj	258	33	(	(	-LRB-
cord-342419-liaihahj	258	34	GenScript	GenScript	NNP
cord-342419-liaihahj	258	35	)	)	-RRB-
cord-342419-liaihahj	258	36	,	,	,
cord-342419-liaihahj	258	37	and	and	CC
cord-342419-liaihahj	258	38	cloned	clone	VBN
cord-342419-liaihahj	258	39	into	into	IN
cord-342419-liaihahj	258	40	vectors	vector	NNS
cord-342419-liaihahj	258	41	encoding	encode	VBG
cord-342419-liaihahj	258	42	human	human	NN
cord-342419-liaihahj	258	43	IgG1	IgG1	NNP
cord-342419-liaihahj	258	44	and	and	CC
cord-342419-liaihahj	258	45	lambda	lambda	NNP
cord-342419-liaihahj	258	46	or	or	CC
cord-342419-liaihahj	258	47	kappa	kappa	NNP
cord-342419-liaihahj	258	48	light	light	NN
cord-342419-liaihahj	258	49	chain	chain	NN
cord-342419-liaihahj	258	50	constant	constant	JJ
cord-342419-liaihahj	258	51	regions	region	NNS
cord-342419-liaihahj	258	52	,	,	,
cord-342419-liaihahj	258	53	respectively	respectively	RB
cord-342419-liaihahj	258	54	.	.	.
cord-342419-liaihahj	259	1	mAbs	mAbs	NNP
cord-342419-liaihahj	259	2	were	be	VBD
cord-342419-liaihahj	259	3	obtained	obtain	VBN
cord-342419-liaihahj	259	4	by	by	IN
cord-342419-liaihahj	259	5	transfection	transfection	NN
cord-342419-liaihahj	259	6	of	of	IN
cord-342419-liaihahj	259	7	plasmids	plasmid	NNS
cord-342419-liaihahj	259	8	into	into	IN
cord-342419-liaihahj	259	9	Expi293F	expi293f	NN
cord-342419-liaihahj	259	10	cells	cell	NNS
cord-342419-liaihahj	259	11	as	as	IN
cord-342419-liaihahj	259	12	described	describe	VBN
cord-342419-liaihahj	259	13	above	above	RB
cord-342419-liaihahj	259	14	.	.	.
cord-342419-liaihahj	260	1	For	for	IN
cord-342419-liaihahj	260	2	hybridoma	hybridoma	NN
cord-342419-liaihahj	260	3	-	-	HYPH
cord-342419-liaihahj	260	4	derived	derive	VBN
cord-342419-liaihahj	260	5	mAbs	mAbs	NNP
cord-342419-liaihahj	260	6	,	,	,
cord-342419-liaihahj	260	7	hybridoma	hybridoma	NN
cord-342419-liaihahj	260	8	cell	cell	NN
cord-342419-liaihahj	260	9	lines	line	NNS
cord-342419-liaihahj	260	10	were	be	VBD
cord-342419-liaihahj	260	11	expanded	expand	VBN
cord-342419-liaihahj	260	12	in	in	IN
cord-342419-liaihahj	260	13	StemCell	StemCell	NNP
cord-342419-liaihahj	260	14	medium	medium	NN
cord-342419-liaihahj	260	15	A	a	NN
cord-342419-liaihahj	260	16	until	until	IN
cord-342419-liaihahj	260	17	80	80	CD
cord-342419-liaihahj	260	18	%	%	NN
cord-342419-liaihahj	260	19	confluent	confluent	JJ
cord-342419-liaihahj	260	20	in	in	IN
cord-342419-liaihahj	260	21	75-cm	75-cm	CD
cord-342419-liaihahj	260	22	2	2	CD
cord-342419-liaihahj	260	23	flasks	flask	NNS
cord-342419-liaihahj	260	24	.	.	.
cord-342419-liaihahj	261	1	Cells	cell	NNS
cord-342419-liaihahj	261	2	from	from	IN
cord-342419-liaihahj	261	3	one	one	CD
cord-342419-liaihahj	261	4	75-cm	75-cm	CD
cord-342419-liaihahj	261	5	2	2	CD
cord-342419-liaihahj	261	6	cell	cell	NN
cord-342419-liaihahj	261	7	culture	culture	NN
cord-342419-liaihahj	261	8	flask	flask	NN
cord-342419-liaihahj	261	9	were	be	VBD
cord-342419-liaihahj	261	10	collected	collect	VBN
cord-342419-liaihahj	261	11	with	with	IN
cord-342419-liaihahj	261	12	a	a	DT
cord-342419-liaihahj	261	13	cell	cell	NN
cord-342419-liaihahj	261	14	scraper	scraper	NN
cord-342419-liaihahj	261	15	and	and	CC
cord-342419-liaihahj	261	16	expanded	expand	VBD
cord-342419-liaihahj	261	17	to	to	IN
cord-342419-liaihahj	261	18	four	four	CD
cord-342419-liaihahj	261	19	225-cm	225-cm	CD
cord-342419-liaihahj	261	20	2	2	CD
cord-342419-liaihahj	261	21	cell	cell	NN
cord-342419-liaihahj	261	22	culture	culture	NN
cord-342419-liaihahj	261	23	flasks	flask	NNS
cord-342419-liaihahj	261	24	in	in	IN
cord-342419-liaihahj	261	25	serum	serum	NN
cord-342419-liaihahj	261	26	-	-	HYPH
cord-342419-liaihahj	261	27	free	free	JJ
cord-342419-liaihahj	261	28	medium	medium	NN
cord-342419-liaihahj	261	29	(	(	-LRB-
cord-342419-liaihahj	261	30	Hybridoma	Hybridoma	NNP
cord-342419-liaihahj	261	31	-	-	HYPH
cord-342419-liaihahj	261	32	SFM	SFM	NNP
cord-342419-liaihahj	261	33	;	;	:
cord-342419-liaihahj	261	34	Thermo	Thermo	NNP
cord-342419-liaihahj	261	35	Fisher	Fisher	NNP
cord-342419-liaihahj	261	36	Scientific	Scientific	NNP
cord-342419-liaihahj	261	37	)	)	-RRB-
cord-342419-liaihahj	261	38	.	.	.
cord-342419-liaihahj	262	1	Recombinant	recombinant	JJ
cord-342419-liaihahj	262	2	cultures	culture	NNS
cord-342419-liaihahj	262	3	from	from	IN
cord-342419-liaihahj	262	4	transfection	transfection	NN
cord-342419-liaihahj	262	5	were	be	VBD
cord-342419-liaihahj	262	6	stopped	stop	VBN
cord-342419-liaihahj	262	7	after	after	IN
cord-342419-liaihahj	262	8	5	5	CD
cord-342419-liaihahj	262	9	to	to	TO
cord-342419-liaihahj	262	10	7	7	CD
cord-342419-liaihahj	262	11	days	day	NNS
cord-342419-liaihahj	262	12	,	,	,
cord-342419-liaihahj	262	13	and	and	CC
cord-342419-liaihahj	262	14	hybridoma	hybridoma	NN
cord-342419-liaihahj	262	15	cultures	culture	NNS
cord-342419-liaihahj	262	16	were	be	VBD
cord-342419-liaihahj	262	17	stopped	stop	VBN
cord-342419-liaihahj	262	18	after	after	IN
cord-342419-liaihahj	262	19	30	30	CD
cord-342419-liaihahj	262	20	days	day	NNS
cord-342419-liaihahj	262	21	.	.	.
cord-342419-liaihahj	263	1	Culture	culture	NN
cord-342419-liaihahj	263	2	supernatants	supernatant	NNS
cord-342419-liaihahj	263	3	from	from	IN
cord-342419-liaihahj	263	4	both	both	DT
cord-342419-liaihahj	263	5	approaches	approach	NNS
cord-342419-liaihahj	263	6	were	be	VBD
cord-342419-liaihahj	263	7	filtered	filter	VBN
cord-342419-liaihahj	263	8	using	use	VBG
cord-342419-liaihahj	263	9	0.45	0.45	CD
cord-342419-liaihahj	263	10	μm	μm	NN
cord-342419-liaihahj	263	11	filters	filter	NNS
cord-342419-liaihahj	263	12	to	to	TO
cord-342419-liaihahj	263	13	remove	remove	VB
cord-342419-liaihahj	263	14	cell	cell	NN
cord-342419-liaihahj	263	15	debris	debris	NN
cord-342419-liaihahj	263	16	.	.	.
cord-342419-liaihahj	264	1	mAbs	mAbs	NNP
cord-342419-liaihahj	264	2	were	be	VBD
cord-342419-liaihahj	264	3	purified	purify	VBN
cord-342419-liaihahj	264	4	directly	directly	RB
cord-342419-liaihahj	264	5	from	from	IN
cord-342419-liaihahj	264	6	culture	culture	NN
cord-342419-liaihahj	264	7	supernatants	supernatant	NNS
cord-342419-liaihahj	264	8	using	use	VBG
cord-342419-liaihahj	264	9	HiTrap	HiTrap	NNP
cord-342419-liaihahj	264	10	protein	protein	NN
cord-342419-liaihahj	264	11	G	g	NN
cord-342419-liaihahj	264	12	columns	column	NNS
cord-342419-liaihahj	264	13	(	(	-LRB-
cord-342419-liaihahj	264	14	GE	GE	NNP
cord-342419-liaihahj	264	15	Healthcare	Healthcare	NNP
cord-342419-liaihahj	264	16	Life	Life	NNP
cord-342419-liaihahj	264	17	Sciences	Sciences	NNPS
cord-342419-liaihahj	264	18	)	)	-RRB-
cord-342419-liaihahj	264	19	according	accord	VBG
cord-342419-liaihahj	264	20	to	to	IN
cord-342419-liaihahj	264	21	the	the	DT
cord-342419-liaihahj	264	22	manufacturer	manufacturer	NN
cord-342419-liaihahj	264	23	's	's	POS
cord-342419-liaihahj	264	24	protocol	protocol	NN
cord-342419-liaihahj	264	25	.	.	.
cord-342419-liaihahj	265	1	To	to	TO
cord-342419-liaihahj	265	2	obtain	obtain	VB
cord-342419-liaihahj	265	3	Fab	fab	JJ
cord-342419-liaihahj	265	4	fragments	fragment	NNS
cord-342419-liaihahj	265	5	,	,	,
cord-342419-liaihahj	265	6	papain	papain	NN
cord-342419-liaihahj	265	7	digestion	digestion	NN
cord-342419-liaihahj	265	8	was	be	VBD
cord-342419-liaihahj	265	9	performed	perform	VBN
cord-342419-liaihahj	265	10	using	use	VBG
cord-342419-liaihahj	265	11	the	the	DT
cord-342419-liaihahj	265	12	Pierce	Pierce	NNP
cord-342419-liaihahj	265	13	Fab	Fab	NNP
cord-342419-liaihahj	265	14	preparation	preparation	NN
cord-342419-liaihahj	265	15	kit	kit	NN
cord-342419-liaihahj	265	16	(	(	-LRB-
cord-342419-liaihahj	265	17	Thermo	Thermo	NNP
cord-342419-liaihahj	265	18	Fisher	Fisher	NNP
cord-342419-liaihahj	265	19	Scientific	Scientific	NNP
cord-342419-liaihahj	265	20	)	)	-RRB-
cord-342419-liaihahj	265	21	according	accord	VBG
cord-342419-liaihahj	265	22	to	to	IN
cord-342419-liaihahj	265	23	the	the	DT
cord-342419-liaihahj	265	24	manufacturer	manufacturer	NN
cord-342419-liaihahj	265	25	's	's	POS
cord-342419-liaihahj	265	26	protocol	protocol	NN
cord-342419-liaihahj	265	27	.	.	.
cord-342419-liaihahj	266	1	Fab	fab	JJ
cord-342419-liaihahj	266	2	fragments	fragment	NNS
cord-342419-liaihahj	266	3	were	be	VBD
cord-342419-liaihahj	266	4	purified	purify	VBN
cord-342419-liaihahj	266	5	by	by	IN
cord-342419-liaihahj	266	6	removing	remove	VBG
cord-342419-liaihahj	266	7	IgG	igg	NN
cord-342419-liaihahj	266	8	and	and	CC
cord-342419-liaihahj	266	9	Fc	Fc	NNP
cord-342419-liaihahj	266	10	contaminants	contaminant	NNS
cord-342419-liaihahj	266	11	using	use	VBG
cord-342419-liaihahj	266	12	a	a	DT
cord-342419-liaihahj	266	13	HiTrap	HiTrap	NNP
cord-342419-liaihahj	266	14	MabSelectSure	mabselectsure	NN
cord-342419-liaihahj	266	15	(	(	-LRB-
cord-342419-liaihahj	266	16	GE	GE	NNP
cord-342419-liaihahj	266	17	Healthcare	Healthcare	NNP
cord-342419-liaihahj	266	18	Life	Life	NNP
cord-342419-liaihahj	266	19	Sciences	Sciences	NNPS
cord-342419-liaihahj	266	20	)	)	-RRB-
cord-342419-liaihahj	266	21	column	column	NN
cord-342419-liaihahj	266	22	according	accord	VBG
cord-342419-liaihahj	266	23	to	to	IN
cord-342419-liaihahj	266	24	the	the	DT
cord-342419-liaihahj	266	25	manufacturer	manufacturer	NN
cord-342419-liaihahj	266	26	's	's	POS
cord-342419-liaihahj	266	27	protocol	protocol	NN
cord-342419-liaihahj	266	28	.	.	.
cord-342419-liaihahj	267	1	For	for	IN
cord-342419-liaihahj	267	2	determination	determination	NN
cord-342419-liaihahj	267	3	of	of	IN
cord-342419-liaihahj	267	4	mAb	mAb	NNP
cord-342419-liaihahj	267	5	isotypes	isotype	NNS
cord-342419-liaihahj	267	6	,	,	,
cord-342419-liaihahj	267	7	96-well	96-well	CD
cord-342419-liaihahj	267	8	Immulon	Immulon	NNP
cord-342419-liaihahj	267	9	HB	HB	NNP
cord-342419-liaihahj	267	10	4×	4×	CD
cord-342419-liaihahj	267	11	ELISA	ELISA	NNP
cord-342419-liaihahj	267	12	plates	plate	NNS
cord-342419-liaihahj	267	13	(	(	-LRB-
cord-342419-liaihahj	267	14	Thermo	Thermo	NNP
cord-342419-liaihahj	267	15	Fisher	Fisher	NNP
cord-342419-liaihahj	267	16	Scientific	Scientific	NNP
cord-342419-liaihahj	267	17	)	)	-RRB-
cord-342419-liaihahj	267	18	were	be	VBD
cord-342419-liaihahj	267	19	coated	coat	VBN
cord-342419-liaihahj	267	20	with	with	IN
cord-342419-liaihahj	267	21	2	2	CD
cord-342419-liaihahj	267	22	μg	μg	NN
cord-342419-liaihahj	267	23	/	/	SYM
cord-342419-liaihahj	267	24	mL	ml	NN
cord-342419-liaihahj	267	25	of	of	IN
cord-342419-liaihahj	267	26	each	each	DT
cord-342419-liaihahj	267	27	mAb	mAb	NNS
cord-342419-liaihahj	267	28	in	in	IN
cord-342419-liaihahj	267	29	PBS	PBS	NNP
cord-342419-liaihahj	267	30	(	(	-LRB-
cord-342419-liaihahj	267	31	duplicate	duplicate	JJ
cord-342419-liaihahj	267	32	wells	well	NNS
cord-342419-liaihahj	267	33	for	for	IN
cord-342419-liaihahj	267	34	each	each	DT
cord-342419-liaihahj	267	35	sample	sample	NN
cord-342419-liaihahj	267	36	)	)	-RRB-
cord-342419-liaihahj	267	37	.	.	.
cord-342419-liaihahj	268	1	The	the	DT
cord-342419-liaihahj	268	2	plates	plate	NNS
cord-342419-liaihahj	268	3	were	be	VBD
cord-342419-liaihahj	268	4	incubated	incubate	VBN
cord-342419-liaihahj	268	5	at	at	IN
cord-342419-liaihahj	268	6	4˚C	4˚c	CD
cord-342419-liaihahj	268	7	overnight	overnight	RB
cord-342419-liaihahj	268	8	and	and	CC
cord-342419-liaihahj	268	9	then	then	RB
cord-342419-liaihahj	268	10	washed	wash	VBD
cord-342419-liaihahj	268	11	once	once	RB
cord-342419-liaihahj	268	12	with	with	IN
cord-342419-liaihahj	268	13	water	water	NN
cord-342419-liaihahj	268	14	.	.	.
cord-342419-liaihahj	269	1	Plates	plate	NNS
cord-342419-liaihahj	269	2	were	be	VBD
cord-342419-liaihahj	269	3	blocked	block	VBN
cord-342419-liaihahj	269	4	with	with	IN
cord-342419-liaihahj	269	5	blocking	block	VBG
cord-342419-liaihahj	269	6	buffer	buffer	NN
cord-342419-liaihahj	269	7	(	(	-LRB-
cord-342419-liaihahj	269	8	2	2	CD
cord-342419-liaihahj	269	9	%	%	NN
cord-342419-liaihahj	269	10	nonfat	nonfat	JJ
cord-342419-liaihahj	269	11	milk	milk	NN
cord-342419-liaihahj	269	12	,	,	,
cord-342419-liaihahj	269	13	2	2	CD
cord-342419-liaihahj	269	14	%	%	NN
cord-342419-liaihahj	269	15	goat	goat	NN
cord-342419-liaihahj	269	16	serum	serum	NN
cord-342419-liaihahj	269	17	in	in	IN
cord-342419-liaihahj	269	18	PBS	PBS	NNP
cord-342419-liaihahj	269	19	with	with	IN
cord-342419-liaihahj	269	20	0.05	0.05	CD
cord-342419-liaihahj	269	21	%	%	NN
cord-342419-liaihahj	269	22	Tween	Tween	NNP
cord-342419-liaihahj	269	23	20	20	CD
cord-342419-liaihahj	269	24	(	(	-LRB-
cord-342419-liaihahj	269	25	PBS	PBS	NNP
cord-342419-liaihahj	269	26	-	-	HYPH
cord-342419-liaihahj	269	27	T	T	NNP
cord-342419-liaihahj	269	28	)	)	-RRB-
cord-342419-liaihahj	269	29	)	)	-RRB-
cord-342419-liaihahj	269	30	and	and	CC
cord-342419-liaihahj	269	31	then	then	RB
cord-342419-liaihahj	269	32	incubated	incubate	VBD
cord-342419-liaihahj	269	33	for	for	IN
cord-342419-liaihahj	269	34	1	1	CD
cord-342419-liaihahj	269	35	hr	hr	NN
cord-342419-liaihahj	269	36	at	at	IN
cord-342419-liaihahj	269	37	room	room	NN
cord-342419-liaihahj	269	38	temperature	temperature	NN
cord-342419-liaihahj	269	39	.	.	.
cord-342419-liaihahj	270	1	After	after	IN
cord-342419-liaihahj	270	2	incubation	incubation	NN
cord-342419-liaihahj	270	3	,	,	,
cord-342419-liaihahj	270	4	the	the	DT
cord-342419-liaihahj	270	5	plates	plate	NNS
cord-342419-liaihahj	270	6	were	be	VBD
cord-342419-liaihahj	270	7	washed	wash	VBN
cord-342419-liaihahj	270	8	three	three	CD
cord-342419-liaihahj	270	9	times	time	NNS
cord-342419-liaihahj	270	10	with	with	IN
cord-342419-liaihahj	270	11	water	water	NN
cord-342419-liaihahj	270	12	.	.	.
cord-342419-liaihahj	271	1	Isotype	Isotype	NNP
cord-342419-liaihahj	271	2	-	-	HYPH
cord-342419-liaihahj	271	3	specific	specific	JJ
cord-342419-liaihahj	271	4	antibodies	antibody	NNS
cord-342419-liaihahj	271	5	obtained	obtain	VBN
cord-342419-liaihahj	271	6	from	from	IN
cord-342419-liaihahj	271	7	Southern	Southern	NNP
cord-342419-liaihahj	271	8	Biotech	Biotech	NNP
cord-342419-liaihahj	271	9	(	(	-LRB-
cord-342419-liaihahj	271	10	goat	goat	NNP
cord-342419-liaihahj	271	11	anti	anti	JJ
cord-342419-liaihahj	271	12	-	-	JJ
cord-342419-liaihahj	271	13	human	human	JJ
cord-342419-liaihahj	271	14	kappa	kappa	NN
cord-342419-liaihahj	271	15	-	-	HYPH
cord-342419-liaihahj	271	16	alkaline	alkaline	JJ
cord-342419-liaihahj	271	17	phosphatase	phosphatase	NN
cord-342419-liaihahj	271	18	[	[	-LRB-
cord-342419-liaihahj	271	19	[	[	-LRB-
cord-342419-liaihahj	272	1	Fc]-AP	Fc]-AP	NNP
cord-342419-liaihahj	273	1	[	[	-LRB-
cord-342419-liaihahj	273	2	catalog	catalog	NN
cord-342419-liaihahj	273	3	number	number	NN
cord-342419-liaihahj	273	4	100245	100245	CD
cord-342419-liaihahj	273	5	-	-	SYM
cord-342419-liaihahj	273	6	812	812	CD
cord-342419-liaihahj	273	7	]	]	-RRB-
cord-342419-liaihahj	273	8	)	)	-RRB-
cord-342419-liaihahj	273	9	were	be	VBD
cord-342419-liaihahj	273	10	diluted	dilute	VBN
cord-342419-liaihahj	273	11	1:1,000	1:1,000	CD
cord-342419-liaihahj	273	12	in	in	IN
cord-342419-liaihahj	273	13	blocking	block	VBG
cord-342419-liaihahj	273	14	buffer	buffer	NN
cord-342419-liaihahj	273	15	,	,	,
cord-342419-liaihahj	273	16	and	and	CC
cord-342419-liaihahj	273	17	50	50	CD
cord-342419-liaihahj	273	18	μl	μl	NN
cord-342419-liaihahj	273	19	of	of	IN
cord-342419-liaihahj	273	20	each	each	DT
cord-342419-liaihahj	273	21	solution	solution	NN
cord-342419-liaihahj	273	22	was	be	VBD
cord-342419-liaihahj	273	23	added	add	VBN
cord-342419-liaihahj	273	24	to	to	IN
cord-342419-liaihahj	273	25	the	the	DT
cord-342419-liaihahj	273	26	respective	respective	JJ
cord-342419-liaihahj	273	27	wells	well	NNS
cord-342419-liaihahj	273	28	.	.	.
cord-342419-liaihahj	274	1	Plates	plate	NNS
cord-342419-liaihahj	274	2	were	be	VBD
cord-342419-liaihahj	274	3	incubated	incubate	VBN
cord-342419-liaihahj	274	4	for	for	IN
cord-342419-liaihahj	274	5	1	1	CD
cord-342419-liaihahj	274	6	hr	hr	NN
cord-342419-liaihahj	274	7	at	at	IN
cord-342419-liaihahj	274	8	room	room	NN
cord-342419-liaihahj	274	9	temperature	temperature	NN
cord-342419-liaihahj	274	10	and	and	CC
cord-342419-liaihahj	274	11	then	then	RB
cord-342419-liaihahj	274	12	washed	wash	VBD
cord-342419-liaihahj	274	13	five	five	CD
cord-342419-liaihahj	274	14	times	time	NNS
cord-342419-liaihahj	274	15	with	with	IN
cord-342419-liaihahj	274	16	PBS	PBS	NNP
cord-342419-liaihahj	274	17	-	-	HYPH
cord-342419-liaihahj	274	18	T.	T.	NNP
cord-342419-liaihahj	275	1	The	the	DT
cord-342419-liaihahj	275	2	PNPP	PNPP	NNP
cord-342419-liaihahj	275	3	substrate	substrate	NN
cord-342419-liaihahj	275	4	was	be	VBD
cord-342419-liaihahj	275	5	prepared	prepare	VBN
cord-342419-liaihahj	275	6	at	at	IN
cord-342419-liaihahj	275	7	1	1	CD
cord-342419-liaihahj	275	8	mg	mg	NNP
cord-342419-liaihahj	275	9	/	/	SYM
cord-342419-liaihahj	275	10	mL	ml	NN
cord-342419-liaihahj	275	11	in	in	IN
cord-342419-liaihahj	275	12	substrate	substrate	NN
cord-342419-liaihahj	275	13	buffer	buffer	NN
cord-342419-liaihahj	275	14	(	(	-LRB-
cord-342419-liaihahj	275	15	1	1	CD
cord-342419-liaihahj	275	16	M	M	NNP
cord-342419-liaihahj	275	17	Tris	Tris	NNP
cord-342419-liaihahj	275	18	base	base	NN
cord-342419-liaihahj	275	19	,	,	,
cord-342419-liaihahj	276	1	0.5	0.5	CD
cord-342419-liaihahj	276	2	mM	mm	CD
cord-342419-liaihahj	276	3	MgCl	MgCl	NNP
cord-342419-liaihahj	276	4	2	2	CD
cord-342419-liaihahj	276	5	,	,	,
cord-342419-liaihahj	276	6	pH	pH	NNP
cord-342419-liaihahj	276	7	9.8	9.8	CD
cord-342419-liaihahj	276	8	)	)	-RRB-
cord-342419-liaihahj	276	9	,	,	,
cord-342419-liaihahj	276	10	and	and	CC
cord-342419-liaihahj	277	1	100	100	CD
cord-342419-liaihahj	277	2	μl	μl	UH
cord-342419-liaihahj	277	3	of	of	IN
cord-342419-liaihahj	277	4	this	this	DT
cord-342419-liaihahj	277	5	solution	solution	NN
cord-342419-liaihahj	277	6	was	be	VBD
cord-342419-liaihahj	277	7	added	add	VBN
cord-342419-liaihahj	277	8	to	to	IN
cord-342419-liaihahj	277	9	each	each	DT
cord-342419-liaihahj	277	10	well	well	RB
cord-342419-liaihahj	277	11	.	.	.
cord-342419-liaihahj	278	1	Plates	plate	NNS
cord-342419-liaihahj	278	2	were	be	VBD
cord-342419-liaihahj	278	3	incubated	incubate	VBN
cord-342419-liaihahj	278	4	for	for	IN
cord-342419-liaihahj	278	5	1	1	CD
cord-342419-liaihahj	278	6	hr	hr	NN
cord-342419-liaihahj	278	7	at	at	IN
cord-342419-liaihahj	278	8	room	room	NN
cord-342419-liaihahj	278	9	temperature	temperature	NN
cord-342419-liaihahj	278	10	and	and	CC
cord-342419-liaihahj	278	11	read	read	VBD
cord-342419-liaihahj	278	12	at	at	IN
cord-342419-liaihahj	278	13	405	405	CD
cord-342419-liaihahj	278	14	nm	nm	NN
cord-342419-liaihahj	278	15	on	on	IN
cord-342419-liaihahj	278	16	a	a	DT
cord-342419-liaihahj	278	17	BioTek	BioTek	NNP
cord-342419-liaihahj	278	18	plate	plate	NN
cord-342419-liaihahj	278	19	reader	reader	NN
cord-342419-liaihahj	278	20	.	.	.
cord-342419-liaihahj	279	1	RNA	RNA	NNP
cord-342419-liaihahj	279	2	was	be	VBD
cord-342419-liaihahj	279	3	isolated	isolate	VBN
cord-342419-liaihahj	279	4	from	from	IN
cord-342419-liaihahj	279	5	expanded	expand	VBN
cord-342419-liaihahj	279	6	hybridoma	hybridoma	NN
cord-342419-liaihahj	279	7	cells	cell	NNS
cord-342419-liaihahj	279	8	using	use	VBG
cord-342419-liaihahj	279	9	the	the	DT
cord-342419-liaihahj	279	10	ENZA	ENZA	NNP
cord-342419-liaihahj	279	11	total	total	NN
cord-342419-liaihahj	279	12	RNA	RNA	NNP
cord-342419-liaihahj	279	13	kit	kit	NN
cord-342419-liaihahj	279	14	(	(	-LRB-
cord-342419-liaihahj	279	15	Omega	Omega	NNP
cord-342419-liaihahj	279	16	Bio	Bio	NNP
cord-342419-liaihahj	279	17	-	-	HYPH
cord-342419-liaihahj	279	18	Tek	Tek	NNP
cord-342419-liaihahj	279	19	)	)	-RRB-
cord-342419-liaihahj	279	20	according	accord	VBG
cord-342419-liaihahj	279	21	to	to	IN
cord-342419-liaihahj	279	22	the	the	DT
cord-342419-liaihahj	279	23	manufacturer	manufacturer	NN
cord-342419-liaihahj	279	24	's	's	POS
cord-342419-liaihahj	279	25	protocol	protocol	NN
cord-342419-liaihahj	279	26	.	.	.
cord-342419-liaihahj	280	1	A	a	DT
cord-342419-liaihahj	280	2	Qiagen	Qiagen	NNP
cord-342419-liaihahj	280	3	OneStep	OneStep	NNP
cord-342419-liaihahj	280	4	RT	RT	NNP
cord-342419-liaihahj	280	5	-	-	HYPH
cord-342419-liaihahj	280	6	PCR	PCR	NNP
cord-342419-liaihahj	280	7	kit	kit	NN
cord-342419-liaihahj	280	8	was	be	VBD
cord-342419-liaihahj	280	9	used	use	VBN
cord-342419-liaihahj	280	10	for	for	IN
cord-342419-liaihahj	280	11	cDNA	cdna	NN
cord-342419-liaihahj	280	12	synthesis	synthesis	NN
cord-342419-liaihahj	280	13	and	and	CC
cord-342419-liaihahj	280	14	PCR	PCR	NNP
cord-342419-liaihahj	280	15	amplification	amplification	NN
cord-342419-liaihahj	280	16	.	.	.
cord-342419-liaihahj	281	1	For	for	IN
cord-342419-liaihahj	281	2	RT	RT	NNP
cord-342419-liaihahj	281	3	-	-	HYPH
cord-342419-liaihahj	281	4	PCR	PCR	NNP
cord-342419-liaihahj	281	5	,	,	,
cord-342419-liaihahj	281	6	50	50	CD
cord-342419-liaihahj	281	7	μl	μl	IN
cord-342419-liaihahj	281	8	reaction	reaction	NN
cord-342419-liaihahj	281	9	mixtures	mixture	NNS
cord-342419-liaihahj	281	10	were	be	VBD
cord-342419-liaihahj	281	11	designed	design	VBN
cord-342419-liaihahj	281	12	with	with	IN
cord-342419-liaihahj	281	13	the	the	DT
cord-342419-liaihahj	281	14	following	follow	VBG
cord-342419-liaihahj	281	15	final	final	JJ
cord-342419-liaihahj	281	16	concentrations	concentration	NNS
cord-342419-liaihahj	281	17	:	:	:
cord-342419-liaihahj	281	18	1×	1×	CD
cord-342419-liaihahj	281	19	Qiagen	Qiagen	NNP
cord-342419-liaihahj	281	20	OneStep	OneStep	NNP
cord-342419-liaihahj	281	21	RT	RT	NNP
cord-342419-liaihahj	281	22	-	-	HYPH
cord-342419-liaihahj	281	23	PCR	PCR	NNP
cord-342419-liaihahj	281	24	buffer	buffer	NN
cord-342419-liaihahj	281	25	,	,	,
cord-342419-liaihahj	281	26	400	400	CD
cord-342419-liaihahj	281	27	μM	μm	CD
cord-342419-liaihahj	281	28	deoxynucleoside	deoxynucleoside	JJ
cord-342419-liaihahj	281	29	triphosphate	triphosphate	NN
cord-342419-liaihahj	281	30	(	(	-LRB-
cord-342419-liaihahj	281	31	dNTP	dNTP	NNP
cord-342419-liaihahj	281	32	)	)	-RRB-
cord-342419-liaihahj	281	33	mix	mix	NN
cord-342419-liaihahj	281	34	,	,	,
cord-342419-liaihahj	281	35	0.6	0.6	CD
cord-342419-liaihahj	281	36	μM	μm	CD
cord-342419-liaihahj	281	37	primer	primer	NN
cord-342419-liaihahj	281	38	mix	mix	NN
cord-342419-liaihahj	281	39	,	,	,
cord-342419-liaihahj	281	40	2	2	CD
cord-342419-liaihahj	281	41	μl	μl	NN
cord-342419-liaihahj	281	42	of	of	IN
cord-342419-liaihahj	281	43	Qiagen	Qiagen	NNP
cord-342419-liaihahj	281	44	OneStep	OneStep	NNP
cord-342419-liaihahj	281	45	RT	RT	NNP
cord-342419-liaihahj	281	46	-	-	HYPH
cord-342419-liaihahj	281	47	PCR	PCR	NNP
cord-342419-liaihahj	281	48	enzyme	enzyme	NN
cord-342419-liaihahj	281	49	mix	mix	NN
cord-342419-liaihahj	281	50	,	,	,
cord-342419-liaihahj	281	51	1	1	CD
cord-342419-liaihahj	281	52	μg	μg	NNP
cord-342419-liaihahj	281	53	total	total	NN
cord-342419-liaihahj	281	54	of	of	IN
cord-342419-liaihahj	281	55	the	the	DT
cord-342419-liaihahj	281	56	template	template	NN
cord-342419-liaihahj	281	57	RNA	RNA	NNP
cord-342419-liaihahj	281	58	,	,	,
cord-342419-liaihahj	281	59	and	and	CC
cord-342419-liaihahj	281	60	RNase	rnase	NN
cord-342419-liaihahj	281	61	-	-	HYPH
cord-342419-liaihahj	281	62	free	free	JJ
cord-342419-liaihahj	281	63	water	water	NN
cord-342419-liaihahj	281	64	.	.	.
cord-342419-liaihahj	282	1	Three	three	CD
cord-342419-liaihahj	282	2	separate	separate	JJ
cord-342419-liaihahj	282	3	sets	set	NNS
cord-342419-liaihahj	282	4	of	of	IN
cord-342419-liaihahj	282	5	primer	primer	NN
cord-342419-liaihahj	282	6	mixes	mix	NNS
cord-342419-liaihahj	282	7	were	be	VBD
cord-342419-liaihahj	282	8	used	use	VBN
cord-342419-liaihahj	282	9	:	:	:
cord-342419-liaihahj	282	10	gamma	gamma	NNP
cord-342419-liaihahj	282	11	,	,	,
cord-342419-liaihahj	282	12	kappa	kappa	NNP
cord-342419-liaihahj	282	13	and	and	CC
cord-342419-liaihahj	282	14	lambda	lambda	NN
cord-342419-liaihahj	282	15	forward	forward	RB
cord-342419-liaihahj	282	16	and	and	CC
cord-342419-liaihahj	282	17	reverse	reverse	VB
cord-342419-liaihahj	282	18	primers	primer	NNS
cord-342419-liaihahj	282	19	as	as	IN
cord-342419-liaihahj	282	20	previously	previously	RB
cord-342419-liaihahj	282	21	described	describe	VBN
cord-342419-liaihahj	282	22	[	[	-LRB-
cord-342419-liaihahj	282	23	71	71	CD
cord-342419-liaihahj	282	24	]	]	-RRB-
cord-342419-liaihahj	282	25	.	.	.
cord-342419-liaihahj	283	1	The	the	DT
cord-342419-liaihahj	283	2	RT	RT	NNP
cord-342419-liaihahj	283	3	-	-	HYPH
cord-342419-liaihahj	283	4	PCR	PCR	NNP
cord-342419-liaihahj	283	5	was	be	VBD
cord-342419-liaihahj	283	6	performed	perform	VBN
cord-342419-liaihahj	283	7	in	in	IN
cord-342419-liaihahj	283	8	a	a	DT
cord-342419-liaihahj	283	9	thermocycler	thermocycler	NN
cord-342419-liaihahj	283	10	with	with	IN
cord-342419-liaihahj	283	11	the	the	DT
cord-342419-liaihahj	283	12	following	follow	VBG
cord-342419-liaihahj	283	13	program	program	NN
cord-342419-liaihahj	283	14	:	:	:
cord-342419-liaihahj	283	15	30	30	CD
cord-342419-liaihahj	283	16	min	min	NN
cord-342419-liaihahj	283	17	at	at	IN
cord-342419-liaihahj	283	18	50˚C	50˚c	CD
cord-342419-liaihahj	283	19	,	,	,
cord-342419-liaihahj	283	20	15	15	CD
cord-342419-liaihahj	283	21	min	min	NN
cord-342419-liaihahj	283	22	at	at	IN
cord-342419-liaihahj	283	23	95˚C	95˚c	CD
cord-342419-liaihahj	283	24	,	,	,
cord-342419-liaihahj	283	25	and	and	CC
cord-342419-liaihahj	283	26	then	then	RB
cord-342419-liaihahj	283	27	a	a	DT
cord-342419-liaihahj	283	28	3-step	3-step	CD
cord-342419-liaihahj	283	29	cycle	cycle	NN
cord-342419-liaihahj	283	30	with	with	IN
cord-342419-liaihahj	283	31	30	30	CD
cord-342419-liaihahj	283	32	repeats	repeat	NNS
cord-342419-liaihahj	283	33	of	of	IN
cord-342419-liaihahj	283	34	denaturation	denaturation	NN
cord-342419-liaihahj	283	35	for	for	IN
cord-342419-liaihahj	283	36	30	30	CD
cord-342419-liaihahj	283	37	s	s	NN
cord-342419-liaihahj	283	38	at	at	IN
cord-342419-liaihahj	283	39	94˚C	94˚c	CD
cord-342419-liaihahj	283	40	,	,	,
cord-342419-liaihahj	283	41	annealing	anneal	VBG
cord-342419-liaihahj	283	42	for	for	IN
cord-342419-liaihahj	283	43	30	30	CD
cord-342419-liaihahj	283	44	s	s	NN
cord-342419-liaihahj	283	45	at	at	IN
cord-342419-liaihahj	283	46	50˚C	50˚c	CD
cord-342419-liaihahj	283	47	,	,	,
cord-342419-liaihahj	283	48	and	and	CC
cord-342419-liaihahj	283	49	extension	extension	NN
cord-342419-liaihahj	283	50	for	for	IN
cord-342419-liaihahj	283	51	1	1	CD
cord-342419-liaihahj	283	52	min	min	NN
cord-342419-liaihahj	283	53	at	at	IN
cord-342419-liaihahj	283	54	72˚C	72˚c	CD
cord-342419-liaihahj	283	55	,	,	,
cord-342419-liaihahj	283	56	followed	follow	VBN
cord-342419-liaihahj	283	57	by	by	IN
cord-342419-liaihahj	283	58	10	10	CD
cord-342419-liaihahj	283	59	min	min	NN
cord-342419-liaihahj	283	60	of	of	IN
cord-342419-liaihahj	283	61	final	final	JJ
cord-342419-liaihahj	283	62	extension	extension	NN
cord-342419-liaihahj	283	63	at	at	IN
cord-342419-liaihahj	283	64	72˚C.	72˚c.	CD
cord-342419-liaihahj	284	1	Samples	sample	NNS
cord-342419-liaihahj	284	2	were	be	VBD
cord-342419-liaihahj	284	3	analyzed	analyze	VBN
cord-342419-liaihahj	284	4	by	by	IN
cord-342419-liaihahj	284	5	agarose	agarose	JJ
cord-342419-liaihahj	284	6	gel	gel	NN
cord-342419-liaihahj	284	7	electrophoresis	electrophoresis	NN
cord-342419-liaihahj	284	8	and	and	CC
cord-342419-liaihahj	284	9	purified	purify	VBN
cord-342419-liaihahj	284	10	PCR	PCR	NNP
cord-342419-liaihahj	284	11	products	product	NNS
cord-342419-liaihahj	284	12	(	(	-LRB-
cord-342419-liaihahj	284	13	ENZA	ENZA	NNP
cord-342419-liaihahj	284	14	cycle	cycle	NN
cord-342419-liaihahj	284	15	pure	pure	JJ
cord-342419-liaihahj	284	16	kit	kit	NN
cord-342419-liaihahj	284	17	;	;	:
cord-342419-liaihahj	284	18	Omega	Omega	NNP
cord-342419-liaihahj	284	19	Biotek	Biotek	NNP
cord-342419-liaihahj	284	20	)	)	-RRB-
cord-342419-liaihahj	284	21	were	be	VBD
cord-342419-liaihahj	284	22	cloned	clone	VBN
cord-342419-liaihahj	284	23	into	into	IN
cord-342419-liaihahj	284	24	the	the	DT
cord-342419-liaihahj	284	25	pCR2.1	pcr2.1	CD
cord-342419-liaihahj	284	26	vector	vector	NN
cord-342419-liaihahj	284	27	using	use	VBG
cord-342419-liaihahj	284	28	the	the	DT
cord-342419-liaihahj	284	29	Original	Original	NNP
cord-342419-liaihahj	284	30	TA	TA	NNP
cord-342419-liaihahj	284	31	cloning	clone	VBG
cord-342419-liaihahj	284	32	kit	kit	NN
cord-342419-liaihahj	284	33	(	(	-LRB-
cord-342419-liaihahj	284	34	Thermo	Thermo	NNP
cord-342419-liaihahj	284	35	Fisher	Fisher	NNP
cord-342419-liaihahj	284	36	Scientific	Scientific	NNP
cord-342419-liaihahj	284	37	)	)	-RRB-
cord-342419-liaihahj	284	38	according	accord	VBG
cord-342419-liaihahj	284	39	to	to	IN
cord-342419-liaihahj	284	40	the	the	DT
cord-342419-liaihahj	284	41	manufacturer	manufacturer	NN
cord-342419-liaihahj	284	42	's	's	POS
cord-342419-liaihahj	284	43	protocol	protocol	NN
cord-342419-liaihahj	284	44	.	.	.
cord-342419-liaihahj	285	1	Plasmids	plasmid	NNS
cord-342419-liaihahj	285	2	were	be	VBD
cord-342419-liaihahj	285	3	purified	purify	VBN
cord-342419-liaihahj	285	4	from	from	IN
cord-342419-liaihahj	285	5	positive	positive	JJ
cord-342419-liaihahj	285	6	DH5α	DH5α	NNP
cord-342419-liaihahj	285	7	colonies	colony	NNS
cord-342419-liaihahj	285	8	with	with	IN
cord-342419-liaihahj	285	9	ENZA	ENZA	NNP
cord-342419-liaihahj	285	10	plasmid	plasmid	NN
cord-342419-liaihahj	285	11	DNA	dna	NN
cord-342419-liaihahj	285	12	mini	mini	NN
cord-342419-liaihahj	285	13	kit	kit	NN
cord-342419-liaihahj	285	14	(	(	-LRB-
cord-342419-liaihahj	285	15	Omega	Omega	NNP
cord-342419-liaihahj	285	16	Biotek	Biotek	NNP
cord-342419-liaihahj	285	17	)	)	-RRB-
cord-342419-liaihahj	285	18	and	and	CC
cord-342419-liaihahj	285	19	submitted	submit	VBN
cord-342419-liaihahj	285	20	to	to	IN
cord-342419-liaihahj	285	21	Genewiz	Genewiz	NNP
cord-342419-liaihahj	285	22	for	for	IN
cord-342419-liaihahj	285	23	sequencing	sequencing	NN
cord-342419-liaihahj	285	24	.	.	.
cord-342419-liaihahj	286	1	Sequences	sequence	NNS
cord-342419-liaihahj	286	2	were	be	VBD
cord-342419-liaihahj	286	3	analyzed	analyze	VBN
cord-342419-liaihahj	286	4	using	use	VBG
cord-342419-liaihahj	286	5	IMGT	IMGT	NNP
cord-342419-liaihahj	286	6	/	/	SYM
cord-342419-liaihahj	286	7	V	v	NN
cord-342419-liaihahj	286	8	-	-	HYPH
cord-342419-liaihahj	286	9	Quest	Quest	NNP
cord-342419-liaihahj	286	10	[	[	-LRB-
cord-342419-liaihahj	286	11	72	72	CD
cord-342419-liaihahj	286	12	]	]	-RRB-
cord-342419-liaihahj	286	13	.	.	.
cord-342419-liaihahj	287	1	For	for	IN
cord-342419-liaihahj	287	2	MPV458	MPV458	NNP
cord-342419-liaihahj	287	3	,	,	,
cord-342419-liaihahj	287	4	2	2	CD
cord-342419-liaihahj	287	5	×	×	NN
cord-342419-liaihahj	287	6	10	10	CD
cord-342419-liaihahj	287	7	6	6	CD
cord-342419-liaihahj	287	8	of	of	IN
cord-342419-liaihahj	287	9	hybridoma	hybridoma	NN
cord-342419-liaihahj	287	10	cells	cell	NNS
cord-342419-liaihahj	287	11	were	be	VBD
cord-342419-liaihahj	287	12	sent	send	VBN
cord-342419-liaihahj	287	13	to	to	IN
cord-342419-liaihahj	287	14	GenScript	GenScript	NNP
cord-342419-liaihahj	287	15	for	for	IN
cord-342419-liaihahj	287	16	antibody	antibody	NN
cord-342419-liaihahj	287	17	variable	variable	JJ
cord-342419-liaihahj	287	18	domain	domain	NN
cord-342419-liaihahj	287	19	sequencing	sequencing	NN
cord-342419-liaihahj	287	20	.	.	.
cord-342419-liaihahj	288	1	For	for	IN
cord-342419-liaihahj	288	2	recombinant	recombinant	JJ
cord-342419-liaihahj	288	3	protein	protein	NN
cord-342419-liaihahj	288	4	capture	capture	NN
cord-342419-liaihahj	288	5	ELISAs	elisa	NNS
cord-342419-liaihahj	288	6	,	,	,
cord-342419-liaihahj	288	7	384-well	384-well	CD
cord-342419-liaihahj	288	8	plates	plate	NNS
cord-342419-liaihahj	288	9	(	(	-LRB-
cord-342419-liaihahj	288	10	Greiner	Greiner	NNP
cord-342419-liaihahj	288	11	Bio	Bio	NNP
cord-342419-liaihahj	288	12	-	-	HYPH
cord-342419-liaihahj	288	13	One	One	NNP
cord-342419-liaihahj	288	14	)	)	-RRB-
cord-342419-liaihahj	288	15	were	be	VBD
cord-342419-liaihahj	288	16	treated	treat	VBN
cord-342419-liaihahj	288	17	with	with	IN
cord-342419-liaihahj	288	18	2	2	CD
cord-342419-liaihahj	288	19	μg	μg	NNP
cord-342419-liaihahj	288	20	/	/	SYM
cord-342419-liaihahj	288	21	ml	ml	NN
cord-342419-liaihahj	288	22	of	of	IN
cord-342419-liaihahj	288	23	antigen	antigen	NN
cord-342419-liaihahj	288	24	in	in	IN
cord-342419-liaihahj	288	25	PBS	PBS	NNP
cord-342419-liaihahj	288	26	for	for	IN
cord-342419-liaihahj	288	27	1	1	CD
cord-342419-liaihahj	288	28	hr	hr	NN
cord-342419-liaihahj	288	29	at	at	IN
cord-342419-liaihahj	288	30	37˚C	37˚c	CD
cord-342419-liaihahj	288	31	or	or	CC
cord-342419-liaihahj	288	32	overnight	overnight	RB
cord-342419-liaihahj	288	33	at	at	IN
cord-342419-liaihahj	288	34	4˚C.	4˚c.	CD
cord-342419-liaihahj	289	1	Following	follow	VBG
cord-342419-liaihahj	289	2	this	this	DT
cord-342419-liaihahj	289	3	,	,	,
cord-342419-liaihahj	289	4	plates	plate	NNS
cord-342419-liaihahj	289	5	were	be	VBD
cord-342419-liaihahj	289	6	washed	wash	VBN
cord-342419-liaihahj	289	7	once	once	RB
cord-342419-liaihahj	289	8	with	with	IN
cord-342419-liaihahj	289	9	water	water	NN
cord-342419-liaihahj	289	10	before	before	IN
cord-342419-liaihahj	289	11	blocking	block	VBG
cord-342419-liaihahj	289	12	for	for	IN
cord-342419-liaihahj	289	13	1	1	CD
cord-342419-liaihahj	289	14	hr	hr	NN
cord-342419-liaihahj	289	15	with	with	IN
cord-342419-liaihahj	289	16	2	2	CD
cord-342419-liaihahj	289	17	%	%	NN
cord-342419-liaihahj	289	18	blocking	block	VBG
cord-342419-liaihahj	289	19	buffer	buffer	NN
cord-342419-liaihahj	289	20	.	.	.
cord-342419-liaihahj	290	1	Primary	Primary	NNP
cord-342419-liaihahj	290	2	mAbs	mAbs	NNP
cord-342419-liaihahj	290	3	or	or	CC
cord-342419-liaihahj	290	4	culture	culture	NN
cord-342419-liaihahj	290	5	supernatants	supernatant	NNS
cord-342419-liaihahj	290	6	were	be	VBD
cord-342419-liaihahj	290	7	applied	apply	VBN
cord-342419-liaihahj	290	8	to	to	IN
cord-342419-liaihahj	290	9	wells	well	NNS
cord-342419-liaihahj	290	10	for	for	IN
cord-342419-liaihahj	290	11	1	1	CD
cord-342419-liaihahj	290	12	hr	hr	NN
cord-342419-liaihahj	290	13	following	follow	VBG
cord-342419-liaihahj	290	14	three	three	CD
cord-342419-liaihahj	290	15	washes	wash	NNS
cord-342419-liaihahj	290	16	with	with	IN
cord-342419-liaihahj	290	17	water	water	NN
cord-342419-liaihahj	290	18	.	.	.
cord-342419-liaihahj	291	1	Plates	plate	NNS
cord-342419-liaihahj	291	2	were	be	VBD
cord-342419-liaihahj	291	3	washed	wash	VBN
cord-342419-liaihahj	291	4	with	with	IN
cord-342419-liaihahj	291	5	water	water	NN
cord-342419-liaihahj	291	6	three	three	CD
cord-342419-liaihahj	291	7	times	time	NNS
cord-342419-liaihahj	291	8	before	before	IN
cord-342419-liaihahj	291	9	applying	apply	VBG
cord-342419-liaihahj	291	10	25	25	CD
cord-342419-liaihahj	291	11	μl	μl	IN
cord-342419-liaihahj	291	12	of	of	IN
cord-342419-liaihahj	291	13	secondary	secondary	JJ
cord-342419-liaihahj	291	14	antibody	antibody	NN
cord-342419-liaihahj	291	15	(	(	-LRB-
cord-342419-liaihahj	291	16	goat	goat	NNP
cord-342419-liaihahj	291	17	anti	anti	JJ
cord-342419-liaihahj	291	18	-	-	JJ
cord-342419-liaihahj	291	19	human	human	JJ
cord-342419-liaihahj	291	20	IgG	igg	NN
cord-342419-liaihahj	291	21	Fc	Fc	NNP
cord-342419-liaihahj	291	22	;	;	:
cord-342419-liaihahj	291	23	Meridian	Meridian	NNP
cord-342419-liaihahj	291	24	Life	Life	NNP
cord-342419-liaihahj	291	25	Science	Science	NNP
cord-342419-liaihahj	291	26	)	)	-RRB-
cord-342419-liaihahj	291	27	at	at	IN
cord-342419-liaihahj	291	28	a	a	DT
cord-342419-liaihahj	291	29	dilution	dilution	NN
cord-342419-liaihahj	291	30	of	of	IN
cord-342419-liaihahj	291	31	1:4,000	1:4,000	CD
cord-342419-liaihahj	291	32	in	in	IN
cord-342419-liaihahj	291	33	blocking	block	VBG
cord-342419-liaihahj	291	34	solution	solution	NN
cord-342419-liaihahj	291	35	.	.	.
cord-342419-liaihahj	292	1	After	after	IN
cord-342419-liaihahj	292	2	incubation	incubation	NN
cord-342419-liaihahj	292	3	for	for	IN
cord-342419-liaihahj	292	4	1	1	CD
cord-342419-liaihahj	292	5	hr	hr	NN
cord-342419-liaihahj	292	6	,	,	,
cord-342419-liaihahj	292	7	the	the	DT
cord-342419-liaihahj	292	8	plates	plate	NNS
cord-342419-liaihahj	292	9	were	be	VBD
cord-342419-liaihahj	292	10	washed	wash	VBN
cord-342419-liaihahj	292	11	five	five	CD
cord-342419-liaihahj	292	12	times	time	NNS
cord-342419-liaihahj	292	13	with	with	IN
cord-342419-liaihahj	292	14	PBS	PBS	NNP
cord-342419-liaihahj	292	15	-	-	HYPH
cord-342419-liaihahj	292	16	T	T	NNP
cord-342419-liaihahj	292	17	,	,	,
cord-342419-liaihahj	292	18	and	and	CC
cord-342419-liaihahj	292	19	25	25	CD
cord-342419-liaihahj	292	20	μl	μl	NN
cord-342419-liaihahj	292	21	of	of	IN
cord-342419-liaihahj	292	22	a	a	DT
cord-342419-liaihahj	292	23	PNPP	pnpp	NN
cord-342419-liaihahj	293	1	(	(	-LRB-
cord-342419-liaihahj	293	2	p	p	NN
cord-342419-liaihahj	293	3	-	-	HYPH
cord-342419-liaihahj	293	4	nitrophenyl	nitrophenyl	NN
cord-342419-liaihahj	293	5	phosphate	phosphate	NN
cord-342419-liaihahj	293	6	)	)	-RRB-
cord-342419-liaihahj	293	7	solution	solution	NN
cord-342419-liaihahj	293	8	(	(	-LRB-
cord-342419-liaihahj	293	9	1	1	CD
cord-342419-liaihahj	293	10	mg	mg	NNP
cord-342419-liaihahj	293	11	/	/	SYM
cord-342419-liaihahj	293	12	ml	ml	NN
cord-342419-liaihahj	293	13	PNPP	PNPP	NNP
cord-342419-liaihahj	293	14	in	in	IN
cord-342419-liaihahj	293	15	1	1	CD
cord-342419-liaihahj	293	16	M	M	NNP
cord-342419-liaihahj	293	17	Tris	Tris	NNP
cord-342419-liaihahj	293	18	base	base	NN
cord-342419-liaihahj	293	19	)	)	-RRB-
cord-342419-liaihahj	293	20	was	be	VBD
cord-342419-liaihahj	293	21	added	add	VBN
cord-342419-liaihahj	293	22	to	to	IN
cord-342419-liaihahj	293	23	each	each	DT
cord-342419-liaihahj	293	24	well	well	RB
cord-342419-liaihahj	293	25	.	.	.
cord-342419-liaihahj	294	1	The	the	DT
cord-342419-liaihahj	294	2	plates	plate	NNS
cord-342419-liaihahj	294	3	were	be	VBD
cord-342419-liaihahj	294	4	incubated	incubate	VBN
cord-342419-liaihahj	294	5	at	at	IN
cord-342419-liaihahj	294	6	room	room	NN
cord-342419-liaihahj	294	7	temperature	temperature	NN
cord-342419-liaihahj	294	8	for	for	IN
cord-342419-liaihahj	294	9	1	1	CD
cord-342419-liaihahj	294	10	hr	hr	NN
cord-342419-liaihahj	294	11	before	before	IN
cord-342419-liaihahj	294	12	reading	read	VBG
cord-342419-liaihahj	294	13	the	the	DT
cord-342419-liaihahj	294	14	optical	optical	JJ
cord-342419-liaihahj	294	15	density	density	NN
cord-342419-liaihahj	294	16	at	at	IN
cord-342419-liaihahj	294	17	405	405	CD
cord-342419-liaihahj	294	18	nm	nm	NN
cord-342419-liaihahj	294	19	on	on	IN
cord-342419-liaihahj	294	20	a	a	DT
cord-342419-liaihahj	294	21	BioTek	BioTek	NNP
cord-342419-liaihahj	294	22	plate	plate	NN
cord-342419-liaihahj	294	23	reader	reader	NN
cord-342419-liaihahj	294	24	.	.	.
cord-342419-liaihahj	295	1	Binding	bind	VBG
cord-342419-liaihahj	295	2	assay	assay	NN
cord-342419-liaihahj	295	3	data	datum	NNS
cord-342419-liaihahj	295	4	were	be	VBD
cord-342419-liaihahj	295	5	analyzed	analyze	VBN
cord-342419-liaihahj	295	6	in	in	IN
cord-342419-liaihahj	295	7	GraphPad	GraphPad	NNP
cord-342419-liaihahj	295	8	Prism	Prism	NNP
cord-342419-liaihahj	295	9	using	use	VBG
cord-342419-liaihahj	295	10	a	a	DT
cord-342419-liaihahj	295	11	nonlinear	nonlinear	JJ
cord-342419-liaihahj	295	12	regression	regression	NN
cord-342419-liaihahj	295	13	curve	curve	NN
cord-342419-liaihahj	295	14	fit	fit	NN
cord-342419-liaihahj	295	15	and	and	CC
cord-342419-liaihahj	295	16	the	the	DT
cord-342419-liaihahj	295	17	log(agonist)-versus	log(agonist)-versus	NN
cord-342419-liaihahj	295	18	-	-	HYPH
cord-342419-liaihahj	295	19	response	response	NN
cord-342419-liaihahj	295	20	function	function	NN
cord-342419-liaihahj	295	21	to	to	TO
cord-342419-liaihahj	295	22	calculate	calculate	VB
cord-342419-liaihahj	295	23	the	the	DT
cord-342419-liaihahj	295	24	binding	bind	VBG
cord-342419-liaihahj	295	25	EC	EC	NNP
cord-342419-liaihahj	295	26	50	50	CD
cord-342419-liaihahj	295	27	values	value	NNS
cord-342419-liaihahj	295	28	.	.	.
cord-342419-liaihahj	296	1	For	for	IN
cord-342419-liaihahj	296	2	all	all	DT
cord-342419-liaihahj	296	3	biosensors	biosensor	NNS
cord-342419-liaihahj	296	4	,	,	,
cord-342419-liaihahj	296	5	an	an	DT
cord-342419-liaihahj	296	6	initial	initial	JJ
cord-342419-liaihahj	296	7	baseline	baseline	NN
cord-342419-liaihahj	296	8	in	in	IN
cord-342419-liaihahj	296	9	running	run	VBG
cord-342419-liaihahj	296	10	buffer	buffer	NN
cord-342419-liaihahj	296	11	(	(	-LRB-
cord-342419-liaihahj	296	12	PBS	PBS	NNP
cord-342419-liaihahj	296	13	,	,	,
cord-342419-liaihahj	296	14	0.5	0.5	CD
cord-342419-liaihahj	296	15	%	%	NN
cord-342419-liaihahj	296	16	bovine	bovine	JJ
cord-342419-liaihahj	296	17	serum	serum	NN
cord-342419-liaihahj	296	18	albumin	albumin	NN
cord-342419-liaihahj	296	19	[	[	-LRB-
cord-342419-liaihahj	296	20	BSA	BSA	NNP
cord-342419-liaihahj	296	21	]	]	-RRB-
cord-342419-liaihahj	296	22	,	,	,
cord-342419-liaihahj	296	23	0.05	0.05	CD
cord-342419-liaihahj	296	24	%	%	NN
cord-342419-liaihahj	296	25	Tween	Tween	NNP
cord-342419-liaihahj	296	26	20	20	CD
cord-342419-liaihahj	296	27	,	,	,
cord-342419-liaihahj	296	28	0.04	0.04	CD
cord-342419-liaihahj	296	29	%	%	NN
cord-342419-liaihahj	296	30	thimerosal	thimerosal	NN
cord-342419-liaihahj	296	31	)	)	-RRB-
cord-342419-liaihahj	296	32	was	be	VBD
cord-342419-liaihahj	296	33	obtained	obtain	VBN
cord-342419-liaihahj	296	34	.	.	.
cord-342419-liaihahj	297	1	For	for	IN
cord-342419-liaihahj	297	2	epitope	epitope	NN
cord-342419-liaihahj	297	3	mapping	mapping	NN
cord-342419-liaihahj	297	4	,	,	,
cord-342419-liaihahj	297	5	100	100	CD
cord-342419-liaihahj	297	6	μg	μg	NN
cord-342419-liaihahj	297	7	/	/	SYM
cord-342419-liaihahj	297	8	mL	mL	NNP
cord-342419-liaihahj	297	9	of	of	IN
cord-342419-liaihahj	297	10	Antibody	Antibody	NNP
cord-342419-liaihahj	297	11	recognition	recognition	NN
cord-342419-liaihahj	297	12	of	of	IN
cord-342419-liaihahj	297	13	the	the	DT
cord-342419-liaihahj	297	14	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	297	15	fusion	fusion	NN
cord-342419-liaihahj	297	16	protein	protein	NN
cord-342419-liaihahj	297	17	trimer	trimer	NN
cord-342419-liaihahj	297	18	interface	interface	NN
cord-342419-liaihahj	298	1	His	-PRON-	PRP$
cord-342419-liaihahj	298	2	-	-	HYPH
cord-342419-liaihahj	298	3	tagged	tagged	NNP
cord-342419-liaihahj	298	4	hMPV	hmpv	NN
cord-342419-liaihahj	298	5	130-BV	130-bv	CD
cord-342419-liaihahj	298	6	F	F	NNP
cord-342419-liaihahj	298	7	[	[	-LRB-
cord-342419-liaihahj	298	8	38	38	CD
cord-342419-liaihahj	298	9	]	]	-RRB-
cord-342419-liaihahj	298	10	protein	protein	NN
cord-342419-liaihahj	298	11	was	be	VBD
cord-342419-liaihahj	298	12	immobilized	immobilize	VBN
cord-342419-liaihahj	298	13	on	on	IN
cord-342419-liaihahj	298	14	anti	anti	JJ
cord-342419-liaihahj	298	15	-	-	JJ
cord-342419-liaihahj	298	16	penta	penta	JJ
cord-342419-liaihahj	298	17	-	-	HYPH
cord-342419-liaihahj	298	18	HIS	his	PRP$
cord-342419-liaihahj	298	19	biosensor	biosensor	NN
cord-342419-liaihahj	298	20	tips	tip	NNS
cord-342419-liaihahj	298	21	(	(	-LRB-
cord-342419-liaihahj	298	22	FortéBio	FortéBio	NNP
cord-342419-liaihahj	298	23	)	)	-RRB-
cord-342419-liaihahj	298	24	for	for	IN
cord-342419-liaihahj	298	25	120	120	CD
cord-342419-liaihahj	298	26	s.	s.	NN
cord-342419-liaihahj	299	1	The	the	DT
cord-342419-liaihahj	299	2	baseline	baseline	JJ
cord-342419-liaihahj	299	3	signal	signal	NN
cord-342419-liaihahj	299	4	was	be	VBD
cord-342419-liaihahj	299	5	measured	measure	VBN
cord-342419-liaihahj	299	6	again	again	RB
cord-342419-liaihahj	299	7	for	for	IN
cord-342419-liaihahj	299	8	60	60	CD
cord-342419-liaihahj	299	9	s	s	NN
cord-342419-liaihahj	299	10	before	before	IN
cord-342419-liaihahj	299	11	biosensor	biosensor	NN
cord-342419-liaihahj	299	12	tips	tip	NNS
cord-342419-liaihahj	299	13	were	be	VBD
cord-342419-liaihahj	299	14	immersed	immerse	VBN
cord-342419-liaihahj	299	15	into	into	IN
cord-342419-liaihahj	299	16	wells	well	NNS
cord-342419-liaihahj	299	17	containing	contain	VBG
cord-342419-liaihahj	299	18	100	100	CD
cord-342419-liaihahj	299	19	μg	μg	NNS
cord-342419-liaihahj	299	20	/	/	SYM
cord-342419-liaihahj	299	21	mL	ml	NN
cord-342419-liaihahj	299	22	of	of	IN
cord-342419-liaihahj	299	23	primary	primary	JJ
cord-342419-liaihahj	299	24	antibody	antibody	NN
cord-342419-liaihahj	299	25	for	for	IN
cord-342419-liaihahj	299	26	300	300	CD
cord-342419-liaihahj	299	27	s.	s.	NNP
cord-342419-liaihahj	300	1	Following	follow	VBG
cord-342419-liaihahj	300	2	this	this	DT
cord-342419-liaihahj	300	3	,	,	,
cord-342419-liaihahj	300	4	biosensors	biosensor	NNS
cord-342419-liaihahj	300	5	were	be	VBD
cord-342419-liaihahj	300	6	immersed	immerse	VBN
cord-342419-liaihahj	300	7	into	into	IN
cord-342419-liaihahj	300	8	wells	well	NNS
cord-342419-liaihahj	300	9	containing	contain	VBG
cord-342419-liaihahj	300	10	100	100	CD
cord-342419-liaihahj	300	11	μg	μg	NNS
cord-342419-liaihahj	300	12	/	/	SYM
cord-342419-liaihahj	300	13	mL	ml	NN
cord-342419-liaihahj	300	14	of	of	IN
cord-342419-liaihahj	300	15	a	a	DT
cord-342419-liaihahj	300	16	second	second	JJ
cord-342419-liaihahj	300	17	mAb	mab	NN
cord-342419-liaihahj	300	18	for	for	IN
cord-342419-liaihahj	300	19	300	300	CD
cord-342419-liaihahj	300	20	s.	s.	NNP
cord-342419-liaihahj	300	21	Percent	Percent	NNP
cord-342419-liaihahj	300	22	binding	bind	VBG
cord-342419-liaihahj	300	23	of	of	IN
cord-342419-liaihahj	300	24	the	the	DT
cord-342419-liaihahj	300	25	second	second	JJ
cord-342419-liaihahj	300	26	mAb	mab	NN
cord-342419-liaihahj	300	27	in	in	IN
cord-342419-liaihahj	300	28	the	the	DT
cord-342419-liaihahj	300	29	presence	presence	NN
cord-342419-liaihahj	300	30	of	of	IN
cord-342419-liaihahj	300	31	the	the	DT
cord-342419-liaihahj	300	32	first	first	JJ
cord-342419-liaihahj	300	33	mAb	mab	NN
cord-342419-liaihahj	300	34	was	be	VBD
cord-342419-liaihahj	300	35	determined	determine	VBN
cord-342419-liaihahj	300	36	by	by	IN
cord-342419-liaihahj	300	37	comparing	compare	VBG
cord-342419-liaihahj	300	38	the	the	DT
cord-342419-liaihahj	300	39	maximal	maximal	JJ
cord-342419-liaihahj	300	40	signal	signal	NN
cord-342419-liaihahj	300	41	of	of	IN
cord-342419-liaihahj	300	42	the	the	DT
cord-342419-liaihahj	300	43	second	second	JJ
cord-342419-liaihahj	300	44	mAb	mab	NN
cord-342419-liaihahj	300	45	after	after	IN
cord-342419-liaihahj	300	46	the	the	DT
cord-342419-liaihahj	300	47	first	first	JJ
cord-342419-liaihahj	300	48	mAb	mab	NN
cord-342419-liaihahj	300	49	was	be	VBD
cord-342419-liaihahj	300	50	added	add	VBN
cord-342419-liaihahj	300	51	to	to	IN
cord-342419-liaihahj	300	52	the	the	DT
cord-342419-liaihahj	300	53	maximum	maximum	JJ
cord-342419-liaihahj	300	54	signal	signal	NN
cord-342419-liaihahj	300	55	of	of	IN
cord-342419-liaihahj	300	56	the	the	DT
cord-342419-liaihahj	300	57	second	second	JJ
cord-342419-liaihahj	300	58	mAb	mab	NN
cord-342419-liaihahj	300	59	alone	alone	RB
cord-342419-liaihahj	300	60	.	.	.
cord-342419-liaihahj	301	1	mAbs	mAbs	NNP
cord-342419-liaihahj	301	2	were	be	VBD
cord-342419-liaihahj	301	3	considered	consider	VBN
cord-342419-liaihahj	301	4	noncompeting	noncompeting	JJ
cord-342419-liaihahj	301	5	if	if	IN
cord-342419-liaihahj	301	6	maximum	maximum	JJ
cord-342419-liaihahj	301	7	binding	binding	NN
cord-342419-liaihahj	301	8	of	of	IN
cord-342419-liaihahj	301	9	the	the	DT
cord-342419-liaihahj	301	10	second	second	JJ
cord-342419-liaihahj	301	11	mAb	mAb	NNP
cord-342419-liaihahj	301	12	was	be	VBD
cord-342419-liaihahj	301	13	�	�	CD
cord-342419-liaihahj	301	14	66	66	CD
cord-342419-liaihahj	301	15	%	%	NN
cord-342419-liaihahj	301	16	of	of	IN
cord-342419-liaihahj	301	17	its	-PRON-	PRP$
cord-342419-liaihahj	301	18	uncompeted	uncompete	VBN
cord-342419-liaihahj	301	19	binding	binding	NN
cord-342419-liaihahj	301	20	.	.	.
cord-342419-liaihahj	302	1	A	a	DT
cord-342419-liaihahj	302	2	level	level	NN
cord-342419-liaihahj	302	3	of	of	IN
cord-342419-liaihahj	302	4	between	between	IN
cord-342419-liaihahj	302	5	33	33	CD
cord-342419-liaihahj	302	6	%	%	NN
cord-342419-liaihahj	302	7	and	and	CC
cord-342419-liaihahj	302	8	66	66	CD
cord-342419-liaihahj	302	9	%	%	NN
cord-342419-liaihahj	302	10	of	of	IN
cord-342419-liaihahj	302	11	its	-PRON-	PRP$
cord-342419-liaihahj	302	12	uncompeted	uncompete	VBN
cord-342419-liaihahj	302	13	binding	binding	NN
cord-342419-liaihahj	302	14	was	be	VBD
cord-342419-liaihahj	302	15	considered	consider	VBN
cord-342419-liaihahj	302	16	intermediate	intermediate	JJ
cord-342419-liaihahj	302	17	competition	competition	NN
cord-342419-liaihahj	302	18	,	,	,
cord-342419-liaihahj	302	19	and	and	CC
cord-342419-liaihahj	302	20	�	�	CD
cord-342419-liaihahj	302	21	33	33	CD
cord-342419-liaihahj	302	22	%	%	NN
cord-342419-liaihahj	302	23	was	be	VBD
cord-342419-liaihahj	302	24	considered	consider	VBN
cord-342419-liaihahj	302	25	competition	competition	NN
cord-342419-liaihahj	302	26	.	.	.
cord-342419-liaihahj	303	1	For	for	IN
cord-342419-liaihahj	303	2	affinity	affinity	NN
cord-342419-liaihahj	303	3	studies	study	NNS
cord-342419-liaihahj	303	4	,	,	,
cord-342419-liaihahj	303	5	monomeric	monomeric	JJ
cord-342419-liaihahj	303	6	hMPV	hmpv	NN
cord-342419-liaihahj	303	7	B2	b2	NN
cord-342419-liaihahj	303	8	F	F	NNP
cord-342419-liaihahj	303	9	protein	protein	NN
cord-342419-liaihahj	303	10	was	be	VBD
cord-342419-liaihahj	303	11	purified	purify	VBN
cord-342419-liaihahj	303	12	by	by	IN
cord-342419-liaihahj	303	13	size	size	NN
cord-342419-liaihahj	303	14	exclusion	exclusion	NN
cord-342419-liaihahj	303	15	chromatography	chromatography	NN
cord-342419-liaihahj	303	16	,	,	,
cord-342419-liaihahj	303	17	biotinylated	biotinylated	JJ
cord-342419-liaihahj	303	18	,	,	,
cord-342419-liaihahj	303	19	and	and	CC
cord-342419-liaihahj	303	20	loaded	load	VBN
cord-342419-liaihahj	303	21	onto	onto	IN
cord-342419-liaihahj	303	22	streptavidin	streptavidin	JJ
cord-342419-liaihahj	303	23	biosensors	biosensor	NNS
cord-342419-liaihahj	303	24	at	at	IN
cord-342419-liaihahj	303	25	10	10	CD
cord-342419-liaihahj	303	26	μg	μg	NN
cord-342419-liaihahj	303	27	/	/	SYM
cord-342419-liaihahj	303	28	mL	ml	NN
cord-342419-liaihahj	303	29	for	for	IN
cord-342419-liaihahj	303	30	10	10	CD
cord-342419-liaihahj	303	31	s	s	NNS
cord-342419-liaihahj	303	32	,	,	,
cord-342419-liaihahj	303	33	and	and	CC
cord-342419-liaihahj	303	34	decreasing	decrease	VBG
cord-342419-liaihahj	303	35	concentrations	concentration	NNS
cord-342419-liaihahj	303	36	of	of	IN
cord-342419-liaihahj	303	37	Fabs	Fabs	NNPS
cord-342419-liaihahj	303	38	were	be	VBD
cord-342419-liaihahj	303	39	analyzed	analyze	VBN
cord-342419-liaihahj	303	40	for	for	IN
cord-342419-liaihahj	303	41	binding	bind	VBG
cord-342419-liaihahj	303	42	by	by	IN
cord-342419-liaihahj	303	43	association	association	NN
cord-342419-liaihahj	303	44	for	for	IN
cord-342419-liaihahj	303	45	300	300	CD
cord-342419-liaihahj	303	46	s	s	NNPS
cord-342419-liaihahj	303	47	and	and	CC
cord-342419-liaihahj	303	48	dissociation	dissociation	NN
cord-342419-liaihahj	303	49	for	for	IN
cord-342419-liaihahj	303	50	600	600	CD
cord-342419-liaihahj	303	51	s.	s.	NNP
cord-342419-liaihahj	303	52	Octet	Octet	NNP
cord-342419-liaihahj	303	53	data	data	NN
cord-342419-liaihahj	303	54	analysis	analysis	NN
cord-342419-liaihahj	303	55	software	software	NN
cord-342419-liaihahj	303	56	was	be	VBD
cord-342419-liaihahj	303	57	used	use	VBN
cord-342419-liaihahj	303	58	to	to	TO
cord-342419-liaihahj	303	59	analyze	analyze	VB
cord-342419-liaihahj	303	60	the	the	DT
cord-342419-liaihahj	303	61	data	datum	NNS
cord-342419-liaihahj	303	62	.	.	.
cord-342419-liaihahj	304	1	Values	value	NNS
cord-342419-liaihahj	304	2	for	for	IN
cord-342419-liaihahj	304	3	reference	reference	NN
cord-342419-liaihahj	304	4	wells	well	NNS
cord-342419-liaihahj	304	5	containing	contain	VBG
cord-342419-liaihahj	304	6	no	no	DT
cord-342419-liaihahj	304	7	antibody	antibody	NN
cord-342419-liaihahj	304	8	were	be	VBD
cord-342419-liaihahj	304	9	subtracted	subtract	VBN
cord-342419-liaihahj	304	10	from	from	IN
cord-342419-liaihahj	304	11	the	the	DT
cord-342419-liaihahj	304	12	data	datum	NNS
cord-342419-liaihahj	304	13	and	and	CC
cord-342419-liaihahj	304	14	were	be	VBD
cord-342419-liaihahj	304	15	fit	fit	JJ
cord-342419-liaihahj	304	16	to	to	IN
cord-342419-liaihahj	304	17	a	a	DT
cord-342419-liaihahj	304	18	1:1	1:1	CD
cord-342419-liaihahj	304	19	binding	binding	NN
cord-342419-liaihahj	304	20	model	model	NN
cord-342419-liaihahj	304	21	.	.	.
cord-342419-liaihahj	305	1	Binding	binding	NN
cord-342419-liaihahj	305	2	curves	curve	NNS
cord-342419-liaihahj	305	3	were	be	VBD
cord-342419-liaihahj	305	4	independently	independently	RB
cord-342419-liaihahj	305	5	graphed	graph	VBN
cord-342419-liaihahj	305	6	in	in	RP
cord-342419-liaihahj	305	7	GraphPad	GraphPad	NNP
cord-342419-liaihahj	305	8	Prism	Prism	NNP
cord-342419-liaihahj	305	9	for	for	IN
cord-342419-liaihahj	305	10	data	datum	NNS
cord-342419-liaihahj	305	11	visualization	visualization	NN
cord-342419-liaihahj	305	12	.	.	.
cord-342419-liaihahj	306	1	hMPV	hMPV	NNP
cord-342419-liaihahj	306	2	plaque	plaque	NN
cord-342419-liaihahj	306	3	neutralization	neutralization	NN
cord-342419-liaihahj	306	4	assay	assay	NN
cord-342419-liaihahj	306	5	LLC	LLC	NNP
cord-342419-liaihahj	306	6	-	-	HYPH
cord-342419-liaihahj	306	7	MK2	MK2	NNP
cord-342419-liaihahj	306	8	cells	cell	NNS
cord-342419-liaihahj	306	9	(	(	-LRB-
cord-342419-liaihahj	306	10	ATCC	ATCC	NNP
cord-342419-liaihahj	306	11	CCL-7	CCL-7	NNP
cord-342419-liaihahj	306	12	)	)	-RRB-
cord-342419-liaihahj	306	13	were	be	VBD
cord-342419-liaihahj	306	14	maintained	maintain	VBN
cord-342419-liaihahj	306	15	in	in	IN
cord-342419-liaihahj	306	16	Opti	Opti	NNP
cord-342419-liaihahj	306	17	-	-	HYPH
cord-342419-liaihahj	306	18	MEM	mem	NN
cord-342419-liaihahj	307	1	(	(	-LRB-
cord-342419-liaihahj	307	2	Thermo	Thermo	NNP
cord-342419-liaihahj	307	3	Fisher	Fisher	NNP
cord-342419-liaihahj	307	4	Scientific	Scientific	NNP
cord-342419-liaihahj	307	5	)	)	-RRB-
cord-342419-liaihahj	307	6	supplemented	supplement	VBD
cord-342419-liaihahj	307	7	with	with	IN
cord-342419-liaihahj	307	8	2	2	CD
cord-342419-liaihahj	307	9	%	%	NN
cord-342419-liaihahj	307	10	heat	heat	NN
cord-342419-liaihahj	307	11	inactivated	inactivate	VBN
cord-342419-liaihahj	307	12	fetal	fetal	JJ
cord-342419-liaihahj	307	13	bovine	bovine	JJ
cord-342419-liaihahj	307	14	serum	serum	NN
cord-342419-liaihahj	307	15	and	and	CC
cord-342419-liaihahj	307	16	grown	grow	VBN
cord-342419-liaihahj	307	17	in	in	IN
cord-342419-liaihahj	307	18	225-cm	225-cm	CD
cord-342419-liaihahj	307	19	2	2	CD
cord-342419-liaihahj	307	20	flask	flask	NN
cord-342419-liaihahj	307	21	at	at	IN
cord-342419-liaihahj	307	22	37˚C	37˚c	CD
cord-342419-liaihahj	307	23	in	in	IN
cord-342419-liaihahj	307	24	a	a	DT
cord-342419-liaihahj	307	25	5	5	CD
cord-342419-liaihahj	307	26	%	%	NN
cord-342419-liaihahj	307	27	CO	co	NN
cord-342419-liaihahj	307	28	2	2	CD
cord-342419-liaihahj	307	29	incubator	incubator	NN
cord-342419-liaihahj	307	30	.	.	.
cord-342419-liaihahj	308	1	Two	two	CD
cord-342419-liaihahj	308	2	days	day	NNS
cord-342419-liaihahj	308	3	prior	prior	RB
cord-342419-liaihahj	308	4	to	to	IN
cord-342419-liaihahj	308	5	neutralization	neutralization	NN
cord-342419-liaihahj	308	6	assays	assay	NNS
cord-342419-liaihahj	308	7	,	,	,
cord-342419-liaihahj	308	8	cells	cell	NNS
cord-342419-liaihahj	308	9	were	be	VBD
cord-342419-liaihahj	308	10	trypsinized	trypsinize	VBN
cord-342419-liaihahj	308	11	and	and	CC
cord-342419-liaihahj	308	12	diluted	dilute	VBN
cord-342419-liaihahj	308	13	in	in	IN
cord-342419-liaihahj	308	14	Opti	Opti	NNP
cord-342419-liaihahj	308	15	-	-	HYPH
cord-342419-liaihahj	308	16	MEM	mem	NN
cord-342419-liaihahj	308	17	at	at	IN
cord-342419-liaihahj	308	18	80,000	80,000	CD
cord-342419-liaihahj	308	19	cells	cell	NNS
cord-342419-liaihahj	308	20	/	/	SYM
cord-342419-liaihahj	308	21	mL	ml	NN
cord-342419-liaihahj	308	22	,	,	,
cord-342419-liaihahj	309	1	0.5	0.5	CD
cord-342419-liaihahj	309	2	mL	ml	NN
cord-342419-liaihahj	309	3	of	of	IN
cord-342419-liaihahj	309	4	cells	cell	NNS
cord-342419-liaihahj	309	5	were	be	VBD
cord-342419-liaihahj	309	6	seeded	seed	VBN
cord-342419-liaihahj	309	7	into	into	IN
cord-342419-liaihahj	309	8	24-well	24-well	CD
cord-342419-liaihahj	309	9	plates	plate	NNS
cord-342419-liaihahj	309	10	.	.	.
cord-342419-liaihahj	310	1	On	on	IN
cord-342419-liaihahj	310	2	the	the	DT
cord-342419-liaihahj	310	3	day	day	NN
cord-342419-liaihahj	310	4	of	of	IN
cord-342419-liaihahj	310	5	the	the	DT
cord-342419-liaihahj	310	6	experiment	experiment	NN
cord-342419-liaihahj	310	7	,	,	,
cord-342419-liaihahj	310	8	serially	serially	RB
cord-342419-liaihahj	310	9	diluted	dilute	VBD
cord-342419-liaihahj	310	10	mAbs	mAbs	NNP
cord-342419-liaihahj	310	11	isolated	isolate	VBN
cord-342419-liaihahj	310	12	from	from	IN
cord-342419-liaihahj	310	13	hybridoma	hybridoma	NN
cord-342419-liaihahj	310	14	supernatants	supernatant	NNS
cord-342419-liaihahj	310	15	were	be	VBD
cord-342419-liaihahj	310	16	incubated	incubate	VBN
cord-342419-liaihahj	310	17	1:1	1:1	CD
cord-342419-liaihahj	310	18	with	with	IN
cord-342419-liaihahj	310	19	a	a	DT
cord-342419-liaihahj	310	20	suspension	suspension	NN
cord-342419-liaihahj	310	21	of	of	IN
cord-342419-liaihahj	310	22	infectious	infectious	JJ
cord-342419-liaihahj	310	23	hMPV	hmpv	NN
cord-342419-liaihahj	310	24	B2	b2	NN
cord-342419-liaihahj	310	25	strain	strain	NN
cord-342419-liaihahj	311	1	TN/93	TN/93	NNP
cord-342419-liaihahj	311	2	-	-	HYPH
cord-342419-liaihahj	311	3	32	32	CD
cord-342419-liaihahj	311	4	or	or	CC
cord-342419-liaihahj	311	5	hMPV	hmpv	NN
cord-342419-liaihahj	311	6	A2	A2	NNP
cord-342419-liaihahj	311	7	strain	strain	NN
cord-342419-liaihahj	311	8	CAN/97	CAN/97	NNP
cord-342419-liaihahj	311	9	-	-	HYPH
cord-342419-liaihahj	311	10	83	83	CD
cord-342419-liaihahj	311	11	for	for	IN
cord-342419-liaihahj	311	12	1	1	CD
cord-342419-liaihahj	311	13	hr	hr	NN
cord-342419-liaihahj	311	14	.	.	.
cord-342419-liaihahj	312	1	Following	follow	VBG
cord-342419-liaihahj	312	2	this	this	DT
cord-342419-liaihahj	312	3	,	,	,
cord-342419-liaihahj	312	4	cells	cell	NNS
cord-342419-liaihahj	312	5	were	be	VBD
cord-342419-liaihahj	312	6	washed	wash	VBN
cord-342419-liaihahj	312	7	twice	twice	RB
cord-342419-liaihahj	312	8	with	with	IN
cord-342419-liaihahj	312	9	PBS	PBS	NNP
cord-342419-liaihahj	312	10	to	to	TO
cord-342419-liaihahj	312	11	remove	remove	VB
cord-342419-liaihahj	312	12	serum	serum	NN
cord-342419-liaihahj	312	13	,	,	,
cord-342419-liaihahj	312	14	and	and	CC
cord-342419-liaihahj	312	15	inoculated	inoculate	VBN
cord-342419-liaihahj	312	16	with	with	IN
cord-342419-liaihahj	312	17	50	50	CD
cord-342419-liaihahj	312	18	μl	μl	NN
cord-342419-liaihahj	312	19	of	of	IN
cord-342419-liaihahj	312	20	the	the	DT
cord-342419-liaihahj	312	21	antibody	antibody	NN
cord-342419-liaihahj	312	22	-	-	HYPH
cord-342419-liaihahj	312	23	virus	virus	NN
cord-342419-liaihahj	312	24	mixture	mixture	NN
cord-342419-liaihahj	312	25	for	for	IN
cord-342419-liaihahj	312	26	1	1	CD
cord-342419-liaihahj	312	27	hr	hr	NN
cord-342419-liaihahj	312	28	with	with	IN
cord-342419-liaihahj	312	29	rocking	rock	VBG
cord-342419-liaihahj	312	30	at	at	IN
cord-342419-liaihahj	312	31	room	room	NN
cord-342419-liaihahj	312	32	temperature	temperature	NN
cord-342419-liaihahj	312	33	.	.	.
cord-342419-liaihahj	313	1	Cells	cell	NNS
cord-342419-liaihahj	313	2	were	be	VBD
cord-342419-liaihahj	313	3	then	then	RB
cord-342419-liaihahj	313	4	overlaid	overlay	VBN
cord-342419-liaihahj	313	5	with	with	IN
cord-342419-liaihahj	313	6	1	1	CD
cord-342419-liaihahj	313	7	mL	ml	NN
cord-342419-liaihahj	313	8	of	of	IN
cord-342419-liaihahj	313	9	0.75	0.75	CD
cord-342419-liaihahj	313	10	%	%	NN
cord-342419-liaihahj	313	11	methylcellulose	methylcellulose	NNS
cord-342419-liaihahj	313	12	dissolved	dissolve	VBN
cord-342419-liaihahj	313	13	in	in	IN
cord-342419-liaihahj	313	14	Opti	Opti	NNP
cord-342419-liaihahj	313	15	-	-	HYPH
cord-342419-liaihahj	313	16	MEM	mem	NN
cord-342419-liaihahj	313	17	supplemented	supplement	VBN
cord-342419-liaihahj	313	18	with	with	IN
cord-342419-liaihahj	313	19	5	5	CD
cord-342419-liaihahj	314	1	μg	μg	NNP
cord-342419-liaihahj	314	2	/	/	SYM
cord-342419-liaihahj	314	3	mL	ml	NN
cord-342419-liaihahj	314	4	trypsin	trypsin	NN
cord-342419-liaihahj	314	5	-	-	HYPH
cord-342419-liaihahj	314	6	EDTA	EDTA	NNP
cord-342419-liaihahj	314	7	and	and	CC
cord-342419-liaihahj	314	8	100	100	CD
cord-342419-liaihahj	314	9	μg	μg	NNS
cord-342419-liaihahj	315	1	/mL	/mL	:
cord-342419-liaihahj	315	2	CaCl	CaCl	NNP
cord-342419-liaihahj	315	3	2	2	CD
cord-342419-liaihahj	315	4	.	.	.
cord-342419-liaihahj	316	1	Cells	cell	NNS
cord-342419-liaihahj	316	2	were	be	VBD
cord-342419-liaihahj	316	3	incubated	incubate	VBN
cord-342419-liaihahj	316	4	for	for	IN
cord-342419-liaihahj	316	5	4	4	CD
cord-342419-liaihahj	316	6	days	day	NNS
cord-342419-liaihahj	316	7	,	,	,
cord-342419-liaihahj	316	8	after	after	IN
cord-342419-liaihahj	316	9	which	which	WDT
cord-342419-liaihahj	316	10	the	the	DT
cord-342419-liaihahj	316	11	cells	cell	NNS
cord-342419-liaihahj	316	12	were	be	VBD
cord-342419-liaihahj	316	13	fixed	fix	VBN
cord-342419-liaihahj	316	14	with	with	IN
cord-342419-liaihahj	316	15	10	10	CD
cord-342419-liaihahj	316	16	%	%	NN
cord-342419-liaihahj	316	17	neutral	neutral	JJ
cord-342419-liaihahj	316	18	buffered	buffer	VBN
cord-342419-liaihahj	316	19	formalin	formalin	NN
cord-342419-liaihahj	316	20	.	.	.
cord-342419-liaihahj	317	1	The	the	DT
cord-342419-liaihahj	317	2	cell	cell	NN
cord-342419-liaihahj	317	3	monolayers	monolayer	NNS
cord-342419-liaihahj	317	4	were	be	VBD
cord-342419-liaihahj	317	5	then	then	RB
cord-342419-liaihahj	317	6	blocked	block	VBN
cord-342419-liaihahj	317	7	with	with	IN
cord-342419-liaihahj	317	8	blocking	block	VBG
cord-342419-liaihahj	317	9	buffer	buffer	NN
cord-342419-liaihahj	317	10	(	(	-LRB-
cord-342419-liaihahj	317	11	2	2	CD
cord-342419-liaihahj	317	12	%	%	NN
cord-342419-liaihahj	317	13	nonfat	nonfat	JJ
cord-342419-liaihahj	317	14	milk	milk	NN
cord-342419-liaihahj	317	15	supplemented	supplement	VBN
cord-342419-liaihahj	317	16	with	with	IN
cord-342419-liaihahj	317	17	2	2	CD
cord-342419-liaihahj	317	18	%	%	NN
cord-342419-liaihahj	317	19	goat	goat	NN
cord-342419-liaihahj	317	20	serum	serum	NN
cord-342419-liaihahj	317	21	in	in	IN
cord-342419-liaihahj	317	22	PBS	PBS	NNP
cord-342419-liaihahj	317	23	-	-	HYPH
cord-342419-liaihahj	317	24	T	T	NNP
cord-342419-liaihahj	317	25	)	)	-RRB-
cord-342419-liaihahj	317	26	for	for	IN
cord-342419-liaihahj	317	27	1	1	CD
cord-342419-liaihahj	317	28	hr	hr	NN
cord-342419-liaihahj	317	29	.	.	.
cord-342419-liaihahj	318	1	The	the	DT
cord-342419-liaihahj	318	2	plates	plate	NNS
cord-342419-liaihahj	318	3	were	be	VBD
cord-342419-liaihahj	318	4	washed	wash	VBN
cord-342419-liaihahj	318	5	with	with	IN
cord-342419-liaihahj	318	6	water	water	NN
cord-342419-liaihahj	318	7	,	,	,
cord-342419-liaihahj	318	8	and	and	CC
cord-342419-liaihahj	318	9	200	200	CD
cord-342419-liaihahj	318	10	μl	μl	NN
cord-342419-liaihahj	318	11	of	of	IN
cord-342419-liaihahj	318	12	mouse	mouse	NN
cord-342419-liaihahj	318	13	anti	anti	JJ
cord-342419-liaihahj	318	14	-	-	JJ
cord-342419-liaihahj	318	15	hMPV	hmpv	JJ
cord-342419-liaihahj	318	16	N	n	CD
cord-342419-liaihahj	318	17	primary	primary	JJ
cord-342419-liaihahj	318	18	antibody	antibody	NN
cord-342419-liaihahj	318	19	(	(	-LRB-
cord-342419-liaihahj	318	20	catalog	catalog	NN
cord-342419-liaihahj	318	21	number	number	NN
cord-342419-liaihahj	318	22	C01851	C01851	NNP
cord-342419-liaihahj	318	23	M	M	NNP
cord-342419-liaihahj	318	24	;	;	:
cord-342419-liaihahj	318	25	Meridian	Meridian	NNP
cord-342419-liaihahj	318	26	Biosciences	Biosciences	NNP
cord-342419-liaihahj	318	27	)	)	-RRB-
cord-342419-liaihahj	318	28	diluted	dilute	VBD
cord-342419-liaihahj	319	1	1:1,000	1:1,000	LS
cord-342419-liaihahj	319	2	in	in	IN
cord-342419-liaihahj	319	3	blocking	block	VBG
cord-342419-liaihahj	319	4	buffer	buffer	NN
cord-342419-liaihahj	319	5	was	be	VBD
cord-342419-liaihahj	319	6	added	add	VBN
cord-342419-liaihahj	319	7	to	to	IN
cord-342419-liaihahj	319	8	each	each	DT
cord-342419-liaihahj	319	9	well	well	RB
cord-342419-liaihahj	319	10	,	,	,
cord-342419-liaihahj	319	11	and	and	CC
cord-342419-liaihahj	319	12	the	the	DT
cord-342419-liaihahj	319	13	plates	plate	NNS
cord-342419-liaihahj	319	14	were	be	VBD
cord-342419-liaihahj	319	15	incubated	incubate	VBN
cord-342419-liaihahj	319	16	for	for	IN
cord-342419-liaihahj	319	17	1	1	CD
cord-342419-liaihahj	319	18	hr	hr	NN
cord-342419-liaihahj	319	19	.	.	.
cord-342419-liaihahj	320	1	The	the	DT
cord-342419-liaihahj	320	2	plates	plate	NNS
cord-342419-liaihahj	320	3	were	be	VBD
cord-342419-liaihahj	320	4	then	then	RB
cord-342419-liaihahj	320	5	washed	wash	VBN
cord-342419-liaihahj	320	6	three	three	CD
cord-342419-liaihahj	320	7	times	time	NNS
cord-342419-liaihahj	320	8	with	with	IN
cord-342419-liaihahj	320	9	water	water	NN
cord-342419-liaihahj	320	10	,	,	,
cord-342419-liaihahj	320	11	after	after	IN
cord-342419-liaihahj	320	12	which	which	WDT
cord-342419-liaihahj	320	13	200	200	CD
cord-342419-liaihahj	320	14	μl	μl	NN
cord-342419-liaihahj	320	15	of	of	IN
cord-342419-liaihahj	320	16	goat	goat	NN
cord-342419-liaihahj	320	17	anti	anti	JJ
cord-342419-liaihahj	320	18	-	-	JJ
cord-342419-liaihahj	320	19	mouse	mouse	JJ
cord-342419-liaihahj	320	20	IgG	igg	NN
cord-342419-liaihahj	320	21	-	-	HYPH
cord-342419-liaihahj	320	22	horseradish	horseradish	NN
cord-342419-liaihahj	320	23	peroxidase	peroxidase	NN
cord-342419-liaihahj	320	24	(	(	-LRB-
cord-342419-liaihahj	320	25	HRP	HRP	NNP
cord-342419-liaihahj	320	26	)	)	-RRB-
cord-342419-liaihahj	320	27	secondary	secondary	JJ
cord-342419-liaihahj	320	28	antibody	antibody	NN
cord-342419-liaihahj	320	29	(	(	-LRB-
cord-342419-liaihahj	320	30	catalog	catalog	NN
cord-342419-liaihahj	320	31	number	number	NN
cord-342419-liaihahj	320	32	5220	5220	CD
cord-342419-liaihahj	320	33	-	-	HYPH
cord-342419-liaihahj	320	34	0286	0286	CD
cord-342419-liaihahj	320	35	;	;	:
cord-342419-liaihahj	320	36	SeraCare	SeraCare	NNP
cord-342419-liaihahj	320	37	)	)	-RRB-
cord-342419-liaihahj	320	38	diluted	dilute	VBD
cord-342419-liaihahj	320	39	1:1,000	1:1,000	CD
cord-342419-liaihahj	320	40	in	in	IN
cord-342419-liaihahj	320	41	blocking	block	VBG
cord-342419-liaihahj	320	42	solution	solution	NN
cord-342419-liaihahj	320	43	was	be	VBD
cord-342419-liaihahj	320	44	added	add	VBN
cord-342419-liaihahj	320	45	to	to	IN
cord-342419-liaihahj	320	46	each	each	DT
cord-342419-liaihahj	320	47	well	well	NN
cord-342419-liaihahj	320	48	for	for	IN
cord-342419-liaihahj	320	49	1	1	CD
cord-342419-liaihahj	320	50	hr	hr	NN
cord-342419-liaihahj	320	51	.	.	.
cord-342419-liaihahj	321	1	Plates	plate	NNS
cord-342419-liaihahj	321	2	were	be	VBD
cord-342419-liaihahj	321	3	then	then	RB
cord-342419-liaihahj	321	4	washed	wash	VBN
cord-342419-liaihahj	321	5	five	five	CD
cord-342419-liaihahj	321	6	times	time	NNS
cord-342419-liaihahj	321	7	with	with	IN
cord-342419-liaihahj	321	8	water	water	NN
cord-342419-liaihahj	321	9	,	,	,
cord-342419-liaihahj	321	10	and	and	CC
cord-342419-liaihahj	321	11	200	200	CD
cord-342419-liaihahj	321	12	μl	μl	NN
cord-342419-liaihahj	321	13	of	of	IN
cord-342419-liaihahj	321	14	TrueBlue	TrueBlue	NNP
cord-342419-liaihahj	321	15	peroxidase	peroxidase	NN
cord-342419-liaihahj	321	16	substrate	substrate	NN
cord-342419-liaihahj	321	17	(	(	-LRB-
cord-342419-liaihahj	321	18	SeraCare	SeraCare	NNP
cord-342419-liaihahj	321	19	)	)	-RRB-
cord-342419-liaihahj	321	20	was	be	VBD
cord-342419-liaihahj	321	21	added	add	VBN
cord-342419-liaihahj	321	22	to	to	IN
cord-342419-liaihahj	321	23	each	each	DT
cord-342419-liaihahj	321	24	well	well	RB
cord-342419-liaihahj	321	25	.	.	.
cord-342419-liaihahj	322	1	Plates	plate	NNS
cord-342419-liaihahj	322	2	were	be	VBD
cord-342419-liaihahj	322	3	incubated	incubate	VBN
cord-342419-liaihahj	322	4	until	until	IN
cord-342419-liaihahj	322	5	plaques	plaque	NNS
cord-342419-liaihahj	322	6	were	be	VBD
cord-342419-liaihahj	322	7	clearly	clearly	RB
cord-342419-liaihahj	322	8	visible	visible	JJ
cord-342419-liaihahj	322	9	.	.	.
cord-342419-liaihahj	323	1	Plaques	plaque	NNS
cord-342419-liaihahj	323	2	were	be	VBD
cord-342419-liaihahj	323	3	counted	count	VBN
cord-342419-liaihahj	323	4	by	by	IN
cord-342419-liaihahj	323	5	hand	hand	NN
cord-342419-liaihahj	323	6	under	under	IN
cord-342419-liaihahj	323	7	a	a	DT
cord-342419-liaihahj	323	8	stereomicroscope	stereomicroscope	NN
cord-342419-liaihahj	323	9	and	and	CC
cord-342419-liaihahj	323	10	compared	compare	VBN
cord-342419-liaihahj	323	11	to	to	IN
cord-342419-liaihahj	323	12	a	a	DT
cord-342419-liaihahj	323	13	virus	virus	NN
cord-342419-liaihahj	323	14	-	-	HYPH
cord-342419-liaihahj	323	15	only	only	RB
cord-342419-liaihahj	323	16	control	control	NN
cord-342419-liaihahj	323	17	,	,	,
cord-342419-liaihahj	323	18	and	and	CC
cord-342419-liaihahj	323	19	the	the	DT
cord-342419-liaihahj	323	20	data	datum	NNS
cord-342419-liaihahj	323	21	were	be	VBD
cord-342419-liaihahj	323	22	analyzed	analyze	VBN
cord-342419-liaihahj	323	23	in	in	IN
cord-342419-liaihahj	323	24	GraphPad	GraphPad	NNP
cord-342419-liaihahj	323	25	Prism	Prism	NNP
cord-342419-liaihahj	323	26	using	use	VBG
cord-342419-liaihahj	323	27	a	a	DT
cord-342419-liaihahj	323	28	nonlinear	nonlinear	JJ
cord-342419-liaihahj	323	29	regression	regression	NN
cord-342419-liaihahj	323	30	curve	curve	NN
cord-342419-liaihahj	323	31	fit	fit	NN
cord-342419-liaihahj	323	32	and	and	CC
cord-342419-liaihahj	323	33	the	the	DT
cord-342419-liaihahj	323	34	log(inhibitor)-versus	log(inhibitor)-versus	NN
cord-342419-liaihahj	323	35	-	-	HYPH
cord-342419-liaihahj	323	36	response	response	NN
cord-342419-liaihahj	323	37	function	function	NN
cord-342419-liaihahj	323	38	to	to	TO
cord-342419-liaihahj	323	39	calculate	calculate	VB
cord-342419-liaihahj	323	40	the	the	DT
cord-342419-liaihahj	323	41	IC	IC	NNP
cord-342419-liaihahj	323	42	50	50	CD
cord-342419-liaihahj	323	43	values	value	NNS
cord-342419-liaihahj	323	44	.	.	.
cord-342419-liaihahj	324	1	Protein	protein	NN
cord-342419-liaihahj	324	2	samples	sample	NNS
cord-342419-liaihahj	324	3	in	in	IN
cord-342419-liaihahj	324	4	reducing	reduce	VBG
cord-342419-liaihahj	324	5	condition	condition	NN
cord-342419-liaihahj	324	6	were	be	VBD
cord-342419-liaihahj	324	7	mixed	mix	VBN
cord-342419-liaihahj	324	8	with	with	IN
cord-342419-liaihahj	324	9	loading	load	VBG
cord-342419-liaihahj	324	10	buffer	buffer	NN
cord-342419-liaihahj	324	11	containing	contain	VBG
cord-342419-liaihahj	324	12	β	β	NNP
cord-342419-liaihahj	324	13	-	-	HYPH
cord-342419-liaihahj	324	14	mercaptoethanol	mercaptoethanol	NNP
cord-342419-liaihahj	324	15	and	and	CC
cord-342419-liaihahj	324	16	heated	heat	VBN
cord-342419-liaihahj	324	17	at	at	IN
cord-342419-liaihahj	324	18	96˚C	96˚c	CD
cord-342419-liaihahj	324	19	for	for	IN
cord-342419-liaihahj	324	20	10	10	CD
cord-342419-liaihahj	324	21	min	min	NN
cord-342419-liaihahj	324	22	before	before	IN
cord-342419-liaihahj	324	23	loading	load	VBG
cord-342419-liaihahj	324	24	on	on	IN
cord-342419-liaihahj	324	25	4	4	CD
cord-342419-liaihahj	324	26	-	-	SYM
cord-342419-liaihahj	324	27	12	12	CD
cord-342419-liaihahj	324	28	%	%	NN
cord-342419-liaihahj	325	1	Bis	Bis	NNP
cord-342419-liaihahj	325	2	-	-	HYPH
cord-342419-liaihahj	325	3	Tris	Tris	NNP
cord-342419-liaihahj	325	4	Plus	plus	CC
cord-342419-liaihahj	325	5	gels	gel	NNS
cord-342419-liaihahj	325	6	(	(	-LRB-
cord-342419-liaihahj	325	7	Invitrogen	Invitrogen	NNP
cord-342419-liaihahj	325	8	)	)	-RRB-
cord-342419-liaihahj	325	9	.	.	.
cord-342419-liaihahj	326	1	Samples	sample	NNS
cord-342419-liaihahj	326	2	in	in	IN
cord-342419-liaihahj	326	3	non	non	JJ
cord-342419-liaihahj	326	4	-	-	JJ
cord-342419-liaihahj	326	5	reducing	reducing	JJ
cord-342419-liaihahj	326	6	conditions	condition	NNS
cord-342419-liaihahj	326	7	were	be	VBD
cord-342419-liaihahj	326	8	diluted	dilute	VBN
cord-342419-liaihahj	326	9	in	in	IN
cord-342419-liaihahj	326	10	loading	load	VBG
cord-342419-liaihahj	326	11	buffer	buffer	NN
cord-342419-liaihahj	326	12	without	without	IN
cord-342419-liaihahj	326	13	any	any	DT
cord-342419-liaihahj	326	14	other	other	JJ
cord-342419-liaihahj	326	15	treatment	treatment	NN
cord-342419-liaihahj	326	16	.	.	.
cord-342419-liaihahj	327	1	Samples	sample	NNS
cord-342419-liaihahj	327	2	were	be	VBD
cord-342419-liaihahj	327	3	transferred	transfer	VBN
cord-342419-liaihahj	327	4	to	to	IN
cord-342419-liaihahj	327	5	PVDF	PVDF	NNP
cord-342419-liaihahj	327	6	membranes	membrane	NNS
cord-342419-liaihahj	327	7	via	via	IN
cord-342419-liaihahj	327	8	iBlot	iblot	NN
cord-342419-liaihahj	327	9	system	system	NN
cord-342419-liaihahj	327	10	(	(	-LRB-
cord-342419-liaihahj	327	11	Invitrogen	Invitrogen	NNP
cord-342419-liaihahj	327	12	)	)	-RRB-
cord-342419-liaihahj	327	13	and	and	CC
cord-342419-liaihahj	327	14	blocked	block	VBD
cord-342419-liaihahj	327	15	with	with	IN
cord-342419-liaihahj	327	16	5	5	CD
cord-342419-liaihahj	327	17	%	%	NN
cord-342419-liaihahj	327	18	blocking	block	VBG
cord-342419-liaihahj	327	19	buffer	buffer	NN
cord-342419-liaihahj	327	20	(	(	-LRB-
cord-342419-liaihahj	327	21	5	5	CD
cord-342419-liaihahj	327	22	%	%	NN
cord-342419-liaihahj	327	23	nonfat	nonfat	JJ
cord-342419-liaihahj	327	24	milk	milk	NN
cord-342419-liaihahj	327	25	,	,	,
cord-342419-liaihahj	327	26	2	2	CD
cord-342419-liaihahj	327	27	%	%	NN
cord-342419-liaihahj	327	28	goat	goat	NN
cord-342419-liaihahj	327	29	serum	serum	NN
cord-342419-liaihahj	327	30	in	in	IN
cord-342419-liaihahj	327	31	PBS	PBS	NNP
cord-342419-liaihahj	327	32	-	-	HYPH
cord-342419-liaihahj	327	33	T	T	NNP
cord-342419-liaihahj	327	34	)	)	-RRB-
cord-342419-liaihahj	327	35	at	at	IN
cord-342419-liaihahj	327	36	4˚C	4˚c	CD
cord-342419-liaihahj	327	37	overnight	overnight	RB
cord-342419-liaihahj	327	38	.	.	.
cord-342419-liaihahj	328	1	Antibody	antibody	NN
cord-342419-liaihahj	328	2	recognition	recognition	NN
cord-342419-liaihahj	328	3	of	of	IN
cord-342419-liaihahj	328	4	the	the	DT
cord-342419-liaihahj	328	5	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	328	6	fusion	fusion	NN
cord-342419-liaihahj	328	7	protein	protein	NN
cord-342419-liaihahj	328	8	trimer	trimer	NN
cord-342419-liaihahj	328	9	interface	interface	NN
cord-342419-liaihahj	328	10	Primary	primary	JJ
cord-342419-liaihahj	328	11	antibodies	antibody	NNS
cord-342419-liaihahj	328	12	were	be	VBD
cord-342419-liaihahj	328	13	diluted	dilute	VBN
cord-342419-liaihahj	328	14	at	at	IN
cord-342419-liaihahj	328	15	0.5	0.5	CD
cord-342419-liaihahj	328	16	μg	μg	NN
cord-342419-liaihahj	328	17	/	/	SYM
cord-342419-liaihahj	328	18	mL	mL	NNP
cord-342419-liaihahj	328	19	in	in	IN
cord-342419-liaihahj	328	20	PBS	PBS	NNP
cord-342419-liaihahj	328	21	-	-	HYPH
cord-342419-liaihahj	328	22	T	T	NNP
cord-342419-liaihahj	328	23	and	and	CC
cord-342419-liaihahj	328	24	HRP	HRP	NNP
cord-342419-liaihahj	328	25	-	-	HYPH
cord-342419-liaihahj	328	26	conjugated	conjugate	VBN
cord-342419-liaihahj	328	27	goat	goat	NN
cord-342419-liaihahj	328	28	anti	anti	JJ
cord-342419-liaihahj	328	29	-	-	JJ
cord-342419-liaihahj	328	30	human	human	JJ
cord-342419-liaihahj	328	31	secondary	secondary	JJ
cord-342419-liaihahj	328	32	antibody	antibody	NN
cord-342419-liaihahj	328	33	was	be	VBD
cord-342419-liaihahj	328	34	diluted	dilute	VBN
cord-342419-liaihahj	328	35	at	at	IN
cord-342419-liaihahj	328	36	1:10,000	1:10,000	CD
cord-342419-liaihahj	328	37	in	in	IN
cord-342419-liaihahj	328	38	PBS	PBS	NNP
cord-342419-liaihahj	328	39	-	-	HYPH
cord-342419-liaihahj	328	40	T.	T.	NNP
cord-342419-liaihahj	329	1	Both	both	DT
cord-342419-liaihahj	329	2	incubations	incubation	NNS
cord-342419-liaihahj	329	3	were	be	VBD
cord-342419-liaihahj	329	4	1	1	CD
cord-342419-liaihahj	329	5	hr	hr	NN
cord-342419-liaihahj	329	6	at	at	IN
cord-342419-liaihahj	329	7	room	room	NN
cord-342419-liaihahj	329	8	temperature	temperature	NN
cord-342419-liaihahj	329	9	with	with	IN
cord-342419-liaihahj	329	10	a	a	DT
cord-342419-liaihahj	329	11	5x	5x	CD
cord-342419-liaihahj	329	12	PBS	PBS	NNP
cord-342419-liaihahj	329	13	-	-	HYPH
cord-342419-liaihahj	329	14	T	T	NNP
cord-342419-liaihahj	329	15	wash	wash	NN
cord-342419-liaihahj	329	16	in	in	RP
cord-342419-liaihahj	329	17	between	between	IN
cord-342419-liaihahj	329	18	.	.	.
cord-342419-liaihahj	330	1	Substrate	Substrate	NNP
cord-342419-liaihahj	330	2	(	(	-LRB-
cord-342419-liaihahj	330	3	Pierce	Pierce	NNP
cord-342419-liaihahj	330	4	ECL	ECL	NNP
cord-342419-liaihahj	330	5	Western	Western	NNP
cord-342419-liaihahj	330	6	Blotting	Blotting	NNP
cord-342419-liaihahj	330	7	Substrate	Substrate	NNP
cord-342419-liaihahj	330	8	,	,	,
cord-342419-liaihahj	330	9	Thermo	Thermo	NNP
cord-342419-liaihahj	330	10	Scientific	Scientific	NNP
cord-342419-liaihahj	330	11	)	)	-RRB-
cord-342419-liaihahj	330	12	was	be	VBD
cord-342419-liaihahj	330	13	added	add	VBN
cord-342419-liaihahj	330	14	immediately	immediately	RB
cord-342419-liaihahj	330	15	before	before	IN
cord-342419-liaihahj	330	16	the	the	DT
cord-342419-liaihahj	330	17	image	image	NN
cord-342419-liaihahj	330	18	was	be	VBD
cord-342419-liaihahj	330	19	taken	take	VBN
cord-342419-liaihahj	330	20	with	with	IN
cord-342419-liaihahj	330	21	ChemiDoc	ChemiDoc	NNP
cord-342419-liaihahj	330	22	Imaging	Imaging	NNP
cord-342419-liaihahj	330	23	System	System	NNP
cord-342419-liaihahj	330	24	(	(	-LRB-
cord-342419-liaihahj	330	25	BioRad	BioRad	NNP
cord-342419-liaihahj	330	26	)	)	-RRB-
cord-342419-liaihahj	330	27	.	.	.
cord-342419-liaihahj	331	1	To	to	TO
cord-342419-liaihahj	331	2	generate	generate	VB
cord-342419-liaihahj	331	3	the	the	DT
cord-342419-liaihahj	331	4	complex	complex	NN
cord-342419-liaihahj	331	5	of	of	IN
cord-342419-liaihahj	331	6	hMPV	hmpv	NN
cord-342419-liaihahj	331	7	B2	b2	NN
cord-342419-liaihahj	331	8	F	F	NNP
cord-342419-liaihahj	331	9	+	+	CC
cord-342419-liaihahj	331	10	MPV458	MPV458	NNP
cord-342419-liaihahj	332	1	Fab	fab	JJ
cord-342419-liaihahj	332	2	complex	complex	NN
cord-342419-liaihahj	332	3	,	,	,
cord-342419-liaihahj	333	1	purified	purify	VBN
cord-342419-liaihahj	333	2	trypsinized	trypsinized	JJ
cord-342419-liaihahj	333	3	B2	B2	NNP
cord-342419-liaihahj	333	4	F	F	NNP
cord-342419-liaihahj	333	5	trimer	trimer	NN
cord-342419-liaihahj	333	6	was	be	VBD
cord-342419-liaihahj	333	7	added	add	VBN
cord-342419-liaihahj	333	8	to	to	IN
cord-342419-liaihahj	333	9	MPV458	MPV458	NNP
cord-342419-liaihahj	333	10	Fab	Fab	NNP
cord-342419-liaihahj	333	11	at	at	IN
cord-342419-liaihahj	333	12	a	a	DT
cord-342419-liaihahj	333	13	1:2	1:2	CD
cord-342419-liaihahj	333	14	molar	molar	JJ
cord-342419-liaihahj	333	15	ratio	ratio	NN
cord-342419-liaihahj	333	16	and	and	CC
cord-342419-liaihahj	333	17	incubate	incubate	VB
cord-342419-liaihahj	333	18	at	at	IN
cord-342419-liaihahj	333	19	4˚C	4˚c	CD
cord-342419-liaihahj	333	20	overnight	overnight	RB
cord-342419-liaihahj	333	21	.	.	.
cord-342419-liaihahj	334	1	To	to	TO
cord-342419-liaihahj	334	2	crystallize	crystallize	VB
cord-342419-liaihahj	334	3	the	the	DT
cord-342419-liaihahj	334	4	complex	complex	NN
cord-342419-liaihahj	334	5	,	,	,
cord-342419-liaihahj	334	6	the	the	DT
cord-342419-liaihahj	334	7	sample	sample	NN
cord-342419-liaihahj	334	8	was	be	VBD
cord-342419-liaihahj	334	9	subjected	subject	VBN
cord-342419-liaihahj	334	10	to	to	IN
cord-342419-liaihahj	334	11	size	size	VB
cord-342419-liaihahj	334	12	exclusion	exclusion	NN
cord-342419-liaihahj	334	13	chromatography	chromatography	NN
cord-342419-liaihahj	334	14	(	(	-LRB-
cord-342419-liaihahj	334	15	S200	S200	NNP
cord-342419-liaihahj	334	16	,	,	,
cord-342419-liaihahj	334	17	16/300	16/300	CD
cord-342419-liaihahj	334	18	,	,	,
cord-342419-liaihahj	334	19	GE	GE	NNP
cord-342419-liaihahj	334	20	Healthcare	Healthcare	NNP
cord-342419-liaihahj	334	21	Life	Life	NNP
cord-342419-liaihahj	334	22	Sciences	Sciences	NNPS
cord-342419-liaihahj	334	23	)	)	-RRB-
cord-342419-liaihahj	334	24	in	in	IN
cord-342419-liaihahj	334	25	50	50	CD
cord-342419-liaihahj	334	26	mM	mm	CD
cord-342419-liaihahj	334	27	Tris	Tris	NNP
cord-342419-liaihahj	334	28	pH	pH	NNP
cord-342419-liaihahj	334	29	7.5	7.5	CD
cord-342419-liaihahj	334	30	,	,	,
cord-342419-liaihahj	334	31	100	100	CD
cord-342419-liaihahj	334	32	mM	mm	CD
cord-342419-liaihahj	334	33	NaCl	nacl	NN
cord-342419-liaihahj	334	34	.	.	.
cord-342419-liaihahj	335	1	The	the	DT
cord-342419-liaihahj	335	2	fractions	fraction	NNS
cord-342419-liaihahj	335	3	containing	contain	VBG
cord-342419-liaihahj	335	4	the	the	DT
cord-342419-liaihahj	335	5	complex	complex	NN
cord-342419-liaihahj	335	6	were	be	VBD
cord-342419-liaihahj	335	7	concentrated	concentrate	VBN
cord-342419-liaihahj	335	8	to	to	IN
cord-342419-liaihahj	335	9	15	15	CD
cord-342419-liaihahj	335	10	mg	mg	NNP
cord-342419-liaihahj	335	11	/	/	SYM
cord-342419-liaihahj	335	12	mL	ml	NN
cord-342419-liaihahj	335	13	and	and	CC
cord-342419-liaihahj	335	14	crystallization	crystallization	NN
cord-342419-liaihahj	335	15	trials	trial	NNS
cord-342419-liaihahj	335	16	were	be	VBD
cord-342419-liaihahj	335	17	prepared	prepare	VBN
cord-342419-liaihahj	335	18	on	on	IN
cord-342419-liaihahj	335	19	a	a	DT
cord-342419-liaihahj	335	20	TTP	TTP	NNP
cord-342419-liaihahj	335	21	LabTech	LabTech	NNP
cord-342419-liaihahj	335	22	Mosquito	Mosquito	NNP
cord-342419-liaihahj	335	23	Robot	Robot	NNP
cord-342419-liaihahj	335	24	in	in	IN
cord-342419-liaihahj	335	25	sitting	sit	VBG
cord-342419-liaihahj	335	26	-	-	HYPH
cord-342419-liaihahj	335	27	drop	drop	NN
cord-342419-liaihahj	335	28	MRC-2	MRC-2	NNP
cord-342419-liaihahj	335	29	plates	plate	NNS
cord-342419-liaihahj	335	30	(	(	-LRB-
cord-342419-liaihahj	335	31	Hampton	Hampton	NNP
cord-342419-liaihahj	335	32	Research	Research	NNP
cord-342419-liaihahj	335	33	)	)	-RRB-
cord-342419-liaihahj	335	34	using	use	VBG
cord-342419-liaihahj	335	35	several	several	JJ
cord-342419-liaihahj	335	36	commercially	commercially	RB
cord-342419-liaihahj	335	37	available	available	JJ
cord-342419-liaihahj	335	38	crystallization	crystallization	NN
cord-342419-liaihahj	335	39	screens	screen	NNS
cord-342419-liaihahj	335	40	.	.	.
cord-342419-liaihahj	336	1	Crystals	crystal	NNS
cord-342419-liaihahj	336	2	were	be	VBD
cord-342419-liaihahj	336	3	obtained	obtain	VBN
cord-342419-liaihahj	336	4	in	in	IN
cord-342419-liaihahj	336	5	the	the	DT
cord-342419-liaihahj	336	6	Crystal	Crystal	NNP
cord-342419-liaihahj	336	7	Screen	Screen	NNP
cord-342419-liaihahj	336	8	HT	HT	NNP
cord-342419-liaihahj	336	9	(	(	-LRB-
cord-342419-liaihahj	336	10	Hampton	Hampton	NNP
cord-342419-liaihahj	336	11	Research	Research	NNP
cord-342419-liaihahj	336	12	)	)	-RRB-
cord-342419-liaihahj	336	13	in	in	IN
cord-342419-liaihahj	336	14	condition	condition	NN
cord-342419-liaihahj	336	15	F3	F3	NNP
cord-342419-liaihahj	336	16	(	(	-LRB-
cord-342419-liaihahj	336	17	0.5	0.5	CD
cord-342419-liaihahj	336	18	M	M	NNP
cord-342419-liaihahj	336	19	Ammonium	ammonium	NN
cord-342419-liaihahj	336	20	sulfate	sulfate	NN
cord-342419-liaihahj	336	21	,	,	,
cord-342419-liaihahj	336	22	0.1	0.1	CD
cord-342419-liaihahj	336	23	M	M	NNP
cord-342419-liaihahj	336	24	Sodium	Sodium	NNP
cord-342419-liaihahj	336	25	citrate	citrate	NN
cord-342419-liaihahj	336	26	tribasic	tribasic	NNP
cord-342419-liaihahj	336	27	dihydrate	dihydrate	NNP
cord-342419-liaihahj	337	1	pH	pH	NNP
cord-342419-liaihahj	337	2	5.6	5.6	CD
cord-342419-liaihahj	337	3	,	,	,
cord-342419-liaihahj	337	4	1.0	1.0	CD
cord-342419-liaihahj	337	5	M	M	NNP
cord-342419-liaihahj	337	6	Lithium	Lithium	NNP
cord-342419-liaihahj	337	7	sulfate	sulfate	NN
cord-342419-liaihahj	337	8	monohydrate	monohydrate	NN
cord-342419-liaihahj	337	9	)	)	-RRB-
cord-342419-liaihahj	337	10	.	.	.
cord-342419-liaihahj	338	1	Crystals	crystal	NNS
cord-342419-liaihahj	338	2	were	be	VBD
cord-342419-liaihahj	338	3	harvested	harvest	VBN
cord-342419-liaihahj	338	4	and	and	CC
cord-342419-liaihahj	338	5	cryo	cryo	NN
cord-342419-liaihahj	338	6	-	-	HYPH
cord-342419-liaihahj	338	7	protected	protect	VBN
cord-342419-liaihahj	338	8	with	with	IN
cord-342419-liaihahj	338	9	30	30	CD
cord-342419-liaihahj	338	10	%	%	NN
cord-342419-liaihahj	338	11	glycerol	glycerol	NN
cord-342419-liaihahj	338	12	in	in	IN
cord-342419-liaihahj	338	13	the	the	DT
cord-342419-liaihahj	338	14	mother	mother	NN
cord-342419-liaihahj	338	15	liquor	liquor	NN
cord-342419-liaihahj	338	16	before	before	IN
cord-342419-liaihahj	338	17	being	be	VBG
cord-342419-liaihahj	338	18	flash	flash	NN
cord-342419-liaihahj	338	19	frozen	freeze	VBN
cord-342419-liaihahj	338	20	in	in	IN
cord-342419-liaihahj	338	21	liquid	liquid	JJ
cord-342419-liaihahj	338	22	nitrogen	nitrogen	NN
cord-342419-liaihahj	338	23	.	.	.
cord-342419-liaihahj	339	1	Xray	Xray	NNP
cord-342419-liaihahj	339	2	diffraction	diffraction	NN
cord-342419-liaihahj	339	3	data	datum	NNS
cord-342419-liaihahj	339	4	were	be	VBD
cord-342419-liaihahj	339	5	collected	collect	VBN
cord-342419-liaihahj	339	6	at	at	IN
cord-342419-liaihahj	339	7	the	the	DT
cord-342419-liaihahj	339	8	Advanced	Advanced	NNP
cord-342419-liaihahj	339	9	Photon	Photon	NNP
cord-342419-liaihahj	339	10	Source	Source	NNP
cord-342419-liaihahj	339	11	SER	SER	NNP
cord-342419-liaihahj	339	12	-	-	HYPH
cord-342419-liaihahj	339	13	CAT	cat	NN
cord-342419-liaihahj	339	14	beamline	beamline	NN
cord-342419-liaihahj	339	15	21-ID	21-id	CD
cord-342419-liaihahj	339	16	-	-	HYPH
cord-342419-liaihahj	339	17	D.	D.	NNP
cord-342419-liaihahj	339	18	Data	Data	NNP
cord-342419-liaihahj	339	19	were	be	VBD
cord-342419-liaihahj	339	20	indexed	index	VBN
cord-342419-liaihahj	339	21	and	and	CC
cord-342419-liaihahj	339	22	scaled	scale	VBN
cord-342419-liaihahj	339	23	using	use	VBG
cord-342419-liaihahj	339	24	XDS	XDS	NNP
cord-342419-liaihahj	339	25	[	[	-LRB-
cord-342419-liaihahj	339	26	73	73	CD
cord-342419-liaihahj	339	27	]	]	-RRB-
cord-342419-liaihahj	339	28	.	.	.
cord-342419-liaihahj	340	1	A	a	DT
cord-342419-liaihahj	340	2	molecular	molecular	JJ
cord-342419-liaihahj	340	3	replacement	replacement	NN
cord-342419-liaihahj	340	4	solution	solution	NN
cord-342419-liaihahj	340	5	was	be	VBD
cord-342419-liaihahj	340	6	obtained	obtain	VBN
cord-342419-liaihahj	340	7	in	in	IN
cord-342419-liaihahj	340	8	Phaser	Phaser	NNP
cord-342419-liaihahj	340	9	[	[	-LRB-
cord-342419-liaihahj	340	10	74	74	CD
cord-342419-liaihahj	340	11	]	]	-RRB-
cord-342419-liaihahj	340	12	using	use	VBG
cord-342419-liaihahj	340	13	the	the	DT
cord-342419-liaihahj	340	14	hMPV	hmpv	NN
cord-342419-liaihahj	340	15	pre	pre	JJ
cord-342419-liaihahj	340	16	-	-	JJ
cord-342419-liaihahj	340	17	fusion	fusion	JJ
cord-342419-liaihahj	340	18	F	F	NNP
cord-342419-liaihahj	340	19	structure	structure	NN
cord-342419-liaihahj	340	20	(	(	-LRB-
cord-342419-liaihahj	340	21	PDB	PDB	NNP
cord-342419-liaihahj	340	22	5WB0	5wb0	CD
cord-342419-liaihahj	340	23	)	)	-RRB-
cord-342419-liaihahj	340	24	and	and	CC
cord-342419-liaihahj	340	25	the	the	DT
cord-342419-liaihahj	340	26	Fab	fab	JJ
cord-342419-liaihahj	340	27	structure	structure	NN
cord-342419-liaihahj	340	28	(	(	-LRB-
cord-342419-liaihahj	340	29	PDB	PDB	NNP
cord-342419-liaihahj	340	30	4Q9Q	4q9q	CD
cord-342419-liaihahj	340	31	)	)	-RRB-
cord-342419-liaihahj	340	32	.	.	.
cord-342419-liaihahj	341	1	The	the	DT
cord-342419-liaihahj	341	2	structure	structure	NN
cord-342419-liaihahj	341	3	of	of	IN
cord-342419-liaihahj	341	4	the	the	DT
cord-342419-liaihahj	341	5	complex	complex	NN
cord-342419-liaihahj	341	6	was	be	VBD
cord-342419-liaihahj	341	7	completed	complete	VBN
cord-342419-liaihahj	341	8	by	by	IN
cord-342419-liaihahj	341	9	manually	manually	RB
cord-342419-liaihahj	341	10	building	build	VBG
cord-342419-liaihahj	341	11	in	in	IN
cord-342419-liaihahj	341	12	COOT	COOT	NNP
cord-342419-liaihahj	341	13	[	[	-LRB-
cord-342419-liaihahj	341	14	75	75	CD
cord-342419-liaihahj	341	15	]	]	-RRB-
cord-342419-liaihahj	341	16	followed	follow	VBN
cord-342419-liaihahj	341	17	by	by	IN
cord-342419-liaihahj	341	18	subsequent	subsequent	JJ
cord-342419-liaihahj	341	19	rounds	round	NNS
cord-342419-liaihahj	341	20	of	of	IN
cord-342419-liaihahj	341	21	manual	manual	JJ
cord-342419-liaihahj	341	22	rebuilding	rebuilding	NN
cord-342419-liaihahj	341	23	and	and	CC
cord-342419-liaihahj	341	24	refinement	refinement	NN
cord-342419-liaihahj	341	25	in	in	IN
cord-342419-liaihahj	341	26	Phenix	Phenix	NNP
cord-342419-liaihahj	341	27	[	[	-LRB-
cord-342419-liaihahj	341	28	74	74	CD
cord-342419-liaihahj	341	29	]	]	-RRB-
cord-342419-liaihahj	341	30	.	.	.
cord-342419-liaihahj	342	1	The	the	DT
cord-342419-liaihahj	342	2	data	datum	NNS
cord-342419-liaihahj	342	3	collection	collection	NN
cord-342419-liaihahj	342	4	and	and	CC
cord-342419-liaihahj	342	5	refinement	refinement	NN
cord-342419-liaihahj	342	6	statistics	statistic	NNS
cord-342419-liaihahj	342	7	are	be	VBP
cord-342419-liaihahj	342	8	shown	show	VBN
cord-342419-liaihahj	342	9	in	in	IN
cord-342419-liaihahj	342	10	S3	S3	NNP
cord-342419-liaihahj	342	11	Table	Table	NNP
cord-342419-liaihahj	342	12	.	.	.
cord-342419-liaihahj	343	1	Flow	flow	NN
cord-342419-liaihahj	343	2	cytometry	cytometry	NN
cord-342419-liaihahj	343	3	of	of	IN
cord-342419-liaihahj	343	4	hMPV	hmpv	NN
cord-342419-liaihahj	343	5	infected	infect	VBN
cord-342419-liaihahj	343	6	LLC	LLC	NNP
cord-342419-liaihahj	343	7	-	-	HYPH
cord-342419-liaihahj	343	8	MK2	MK2	NNP
cord-342419-liaihahj	343	9	cells	cell	NNS
cord-342419-liaihahj	344	1	LLC	LLC	NNP
cord-342419-liaihahj	344	2	-	-	HYPH
cord-342419-liaihahj	344	3	MK2	MK2	NNP
cord-342419-liaihahj	344	4	cells	cell	NNS
cord-342419-liaihahj	344	5	were	be	VBD
cord-342419-liaihahj	344	6	cultured	culture	VBN
cord-342419-liaihahj	344	7	in	in	IN
cord-342419-liaihahj	344	8	75-cm	75-cm	CD
cord-342419-liaihahj	344	9	2	2	CD
cord-342419-liaihahj	344	10	flask	flask	NN
cord-342419-liaihahj	344	11	at	at	IN
cord-342419-liaihahj	344	12	80	80	CD
cord-342419-liaihahj	344	13	-	-	SYM
cord-342419-liaihahj	344	14	90	90	CD
cord-342419-liaihahj	344	15	%	%	NN
cord-342419-liaihahj	344	16	confluency	confluency	NN
cord-342419-liaihahj	344	17	,	,	,
cord-342419-liaihahj	344	18	and	and	CC
cord-342419-liaihahj	344	19	then	then	RB
cord-342419-liaihahj	344	20	infected	infect	VBN
cord-342419-liaihahj	344	21	with	with	IN
cord-342419-liaihahj	344	22	hMPV	hmpv	NN
cord-342419-liaihahj	344	23	(	(	-LRB-
cord-342419-liaihahj	344	24	CAN/97	CAN/97	NNP
cord-342419-liaihahj	344	25	-	-	HYPH
cord-342419-liaihahj	344	26	83	83	CD
cord-342419-liaihahj	344	27	)	)	-RRB-
cord-342419-liaihahj	344	28	at	at	IN
cord-342419-liaihahj	344	29	0.1	0.1	CD
cord-342419-liaihahj	344	30	MOI	MOI	NNP
cord-342419-liaihahj	344	31	in	in	IN
cord-342419-liaihahj	344	32	Opti	Opti	NNP
cord-342419-liaihahj	344	33	-	-	HYPH
cord-342419-liaihahj	344	34	MEM	mem	NN
cord-342419-liaihahj	344	35	containing	contain	VBG
cord-342419-liaihahj	344	36	100	100	CD
cord-342419-liaihahj	345	1	μg	μg	NNP
cord-342419-liaihahj	345	2	/	/	SYM
cord-342419-liaihahj	345	3	mL	mL	NNP
cord-342419-liaihahj	345	4	CaCl	CaCl	NNP
cord-342419-liaihahj	345	5	2	2	CD
cord-342419-liaihahj	345	6	and	and	CC
cord-342419-liaihahj	345	7	5	5	CD
cord-342419-liaihahj	345	8	μg	μg	XX
cord-342419-liaihahj	346	1	/mL	/mL	NFP
cord-342419-liaihahj	346	2	trypsin	trypsin	NN
cord-342419-liaihahj	346	3	-	-	HYPH
cord-342419-liaihahj	346	4	EDTA	EDTA	NNP
cord-342419-liaihahj	346	5	.	.	.
cord-342419-liaihahj	347	1	After	after	IN
cord-342419-liaihahj	347	2	48	48	CD
cord-342419-liaihahj	347	3	hrs	hrs	NN
cord-342419-liaihahj	347	4	,	,	,
cord-342419-liaihahj	347	5	cells	cell	NNS
cord-342419-liaihahj	347	6	were	be	VBD
cord-342419-liaihahj	347	7	washed	wash	VBN
cord-342419-liaihahj	347	8	twice	twice	RB
cord-342419-liaihahj	347	9	with	with	IN
cord-342419-liaihahj	347	10	PBS	PBS	NNP
cord-342419-liaihahj	347	11	and	and	CC
cord-342419-liaihahj	347	12	digested	digest	VBN
cord-342419-liaihahj	347	13	with	with	IN
cord-342419-liaihahj	347	14	Versene	Versene	NNP
cord-342419-liaihahj	347	15	(	(	-LRB-
cord-342419-liaihahj	347	16	Gibco	Gibco	NNP
cord-342419-liaihahj	347	17	)	)	-RRB-
cord-342419-liaihahj	347	18	at	at	IN
cord-342419-liaihahj	347	19	37˚C	37˚c	CD
cord-342419-liaihahj	347	20	for	for	IN
cord-342419-liaihahj	347	21	40	40	CD
cord-342419-liaihahj	347	22	-	-	SYM
cord-342419-liaihahj	347	23	50	50	CD
cord-342419-liaihahj	347	24	minutes	minute	NNS
cord-342419-liaihahj	347	25	.	.	.
cord-342419-liaihahj	348	1	Cells	cell	NNS
cord-342419-liaihahj	348	2	were	be	VBD
cord-342419-liaihahj	348	3	washed	wash	VBN
cord-342419-liaihahj	348	4	once	once	RB
cord-342419-liaihahj	348	5	with	with	IN
cord-342419-liaihahj	348	6	PBS	PBS	NNP
cord-342419-liaihahj	348	7	then	then	RB
cord-342419-liaihahj	348	8	transferred	transfer	VBD
cord-342419-liaihahj	348	9	to	to	IN
cord-342419-liaihahj	348	10	1.5	1.5	CD
cord-342419-liaihahj	348	11	mL	ml	NN
cord-342419-liaihahj	348	12	tubes	tube	NNS
cord-342419-liaihahj	348	13	,	,	,
cord-342419-liaihahj	348	14	pelleted	pellete	VBN
cord-342419-liaihahj	348	15	and	and	CC
cord-342419-liaihahj	348	16	resuspended	resuspend	VBD
cord-342419-liaihahj	348	17	in	in	IN
cord-342419-liaihahj	348	18	1	1	CD
cord-342419-liaihahj	348	19	mL	mL	NNP
cord-342419-liaihahj	348	20	FACS	FACS	NNP
cord-342419-liaihahj	348	21	buffer	buffer	NN
cord-342419-liaihahj	348	22	(	(	-LRB-
cord-342419-liaihahj	348	23	PBS	PBS	NNP
cord-342419-liaihahj	348	24	containing	contain	VBG
cord-342419-liaihahj	348	25	5	5	CD
cord-342419-liaihahj	348	26	%	%	NN
cord-342419-liaihahj	348	27	FBS	FBS	NNP
cord-342419-liaihahj	348	28	,	,	,
cord-342419-liaihahj	348	29	inactivated	inactivate	VBD
cord-342419-liaihahj	348	30	2	2	CD
cord-342419-liaihahj	348	31	%	%	NN
cord-342419-liaihahj	348	32	Human	human	JJ
cord-342419-liaihahj	348	33	serum	serum	NN
cord-342419-liaihahj	348	34	,	,	,
cord-342419-liaihahj	348	35	inactivated	inactivate	VBD
cord-342419-liaihahj	348	36	2	2	CD
cord-342419-liaihahj	348	37	%	%	NN
cord-342419-liaihahj	348	38	goat	goat	NN
cord-342419-liaihahj	348	39	serum	serum	NN
cord-342419-liaihahj	348	40	,	,	.
cord-342419-liaihahj	349	1	2	2	LS
cord-342419-liaihahj	349	2	mM	mm	CD
cord-342419-liaihahj	349	3	EDTA	edta	NN
cord-342419-liaihahj	349	4	pH	ph	NN
cord-342419-liaihahj	350	1	8.0	8.0	CD
cord-342419-liaihahj	350	2	,	,	,
cord-342419-liaihahj	350	3	10	10	CD
cord-342419-liaihahj	350	4	%	%	NN
cord-342419-liaihahj	350	5	sodium	sodium	NN
cord-342419-liaihahj	350	6	azide	azide	NN
cord-342419-liaihahj	350	7	)	)	-RRB-
cord-342419-liaihahj	350	8	and	and	CC
cord-342419-liaihahj	350	9	incubated	incubate	VBN
cord-342419-liaihahj	350	10	for	for	IN
cord-342419-liaihahj	350	11	30	30	CD
cord-342419-liaihahj	350	12	min	min	NN
cord-342419-liaihahj	350	13	to	to	TO
cord-342419-liaihahj	350	14	block	block	VB
cord-342419-liaihahj	350	15	Fc	Fc	NNP
cord-342419-liaihahj	350	16	receptors	receptor	NNS
cord-342419-liaihahj	350	17	.	.	.
cord-342419-liaihahj	351	1	Cells	cell	NNS
cord-342419-liaihahj	351	2	were	be	VBD
cord-342419-liaihahj	351	3	washed	wash	VBN
cord-342419-liaihahj	351	4	three	three	CD
cord-342419-liaihahj	351	5	times	time	NNS
cord-342419-liaihahj	351	6	with	with	IN
cord-342419-liaihahj	351	7	PBS	PBS	NNP
cord-342419-liaihahj	351	8	,	,	,
cord-342419-liaihahj	351	9	then	then	RB
cord-342419-liaihahj	351	10	aliquoted	aliquote	VBD
cord-342419-liaihahj	351	11	in	in	IN
cord-342419-liaihahj	351	12	a	a	DT
cord-342419-liaihahj	351	13	96	96	CD
cord-342419-liaihahj	351	14	well	well	UH
cord-342419-liaihahj	351	15	U	u	NN
cord-342419-liaihahj	351	16	bottom	bottom	NN
cord-342419-liaihahj	351	17	plate	plate	NN
cord-342419-liaihahj	351	18	for	for	IN
cord-342419-liaihahj	351	19	antibody	antibody	NN
cord-342419-liaihahj	351	20	staining	staining	NN
cord-342419-liaihahj	351	21	.	.	.
cord-342419-liaihahj	352	1	Mouse	Mouse	NNP
cord-342419-liaihahj	352	2	anti	anti	JJ
cord-342419-liaihahj	352	3	-	-	JJ
cord-342419-liaihahj	352	4	human	human	JJ
cord-342419-liaihahj	352	5	IgG	igg	NN
cord-342419-liaihahj	352	6	Fc	Fc	NNP
cord-342419-liaihahj	352	7	APC	APC	NNP
cord-342419-liaihahj	352	8	(	(	-LRB-
cord-342419-liaihahj	352	9	BioLegend	BioLegend	NNP
cord-342419-liaihahj	352	10	,	,	,
cord-342419-liaihahj	352	11	409306	409306	CD
cord-342419-liaihahj	352	12	)	)	-RRB-
cord-342419-liaihahj	352	13	was	be	VBD
cord-342419-liaihahj	352	14	used	use	VBN
cord-342419-liaihahj	352	15	for	for	IN
cord-342419-liaihahj	352	16	secondary	secondary	JJ
cord-342419-liaihahj	352	17	antibody	antibody	NN
cord-342419-liaihahj	352	18	staining	staining	NN
cord-342419-liaihahj	352	19	.	.	.
cord-342419-liaihahj	353	1	Stained	stained	JJ
cord-342419-liaihahj	353	2	cells	cell	NNS
cord-342419-liaihahj	353	3	were	be	VBD
cord-342419-liaihahj	353	4	fixed	fix	VBN
cord-342419-liaihahj	353	5	in	in	IN
cord-342419-liaihahj	353	6	4	4	CD
cord-342419-liaihahj	353	7	%	%	NN
cord-342419-liaihahj	353	8	paraformaldehyde	paraformaldehyde	NNP
cord-342419-liaihahj	353	9	and	and	CC
cord-342419-liaihahj	353	10	data	datum	NNS
cord-342419-liaihahj	353	11	was	be	VBD
cord-342419-liaihahj	353	12	collected	collect	VBN
cord-342419-liaihahj	353	13	with	with	IN
cord-342419-liaihahj	353	14	Beckman	Beckman	NNP
cord-342419-liaihahj	353	15	Coulter	Coulter	NNP
cord-342419-liaihahj	353	16	CytoFLEX	CytoFLEX	NNP
cord-342419-liaihahj	353	17	flow	flow	NN
cord-342419-liaihahj	353	18	cytometer	cytometer	NN
cord-342419-liaihahj	353	19	.	.	.
cord-342419-liaihahj	354	1	Data	datum	NNS
cord-342419-liaihahj	354	2	were	be	VBD
cord-342419-liaihahj	354	3	analyzed	analyze	VBN
cord-342419-liaihahj	354	4	in	in	IN
cord-342419-liaihahj	354	5	FlowJo	FlowJo	NNP
cord-342419-liaihahj	354	6	.	.	.
cord-342419-liaihahj	355	1	In	in	IN
cord-342419-liaihahj	355	2	(	(	-LRB-
cord-342419-liaihahj	355	3	A	a	NN
cord-342419-liaihahj	355	4	)	)	-RRB-
cord-342419-liaihahj	355	5	,	,	,
cord-342419-liaihahj	355	6	hMPV	hmpv	NN
cord-342419-liaihahj	355	7	F	F	NNP
cord-342419-liaihahj	355	8	protein	protein	NN
cord-342419-liaihahj	355	9	loaded	load	VBN
cord-342419-liaihahj	355	10	biosensors	biosensor	NNS
cord-342419-liaihahj	355	11	are	be	VBP
cord-342419-liaihahj	355	12	exposed	expose	VBN
cord-342419-liaihahj	355	13	to	to	IN
cord-342419-liaihahj	355	14	each	each	DT
cord-342419-liaihahj	355	15	mAb	mAb	NNS
cord-342419-liaihahj	355	16	displayed	display	VBN
cord-342419-liaihahj	355	17	in	in	IN
cord-342419-liaihahj	355	18	the	the	DT
cord-342419-liaihahj	355	19	legend	legend	NN
cord-342419-liaihahj	355	20	.	.	.
cord-342419-liaihahj	356	1	In	in	IN
cord-342419-liaihahj	356	2	(	(	-LRB-
cord-342419-liaihahj	356	3	B	b	NN
cord-342419-liaihahj	356	4	)	)	-RRB-
cord-342419-liaihahj	356	5	and	and	CC
cord-342419-liaihahj	356	6	(	(	-LRB-
cord-342419-liaihahj	356	7	C	C	NNP
cord-342419-liaihahj	356	8	)	)	-RRB-
cord-342419-liaihahj	356	9	,	,	,
cord-342419-liaihahj	356	10	the	the	DT
cord-342419-liaihahj	356	11	biosensors	biosensor	NNS
cord-342419-liaihahj	356	12	loaded	load	VBN
cord-342419-liaihahj	356	13	with	with	IN
cord-342419-liaihahj	356	14	the	the	DT
cord-342419-liaihahj	356	15	first	first	JJ
cord-342419-liaihahj	356	16	mAb	mAb	NNS
cord-342419-liaihahj	356	17	are	be	VBP
cord-342419-liaihahj	356	18	exposed	expose	VBN
cord-342419-liaihahj	356	19	to	to	IN
cord-342419-liaihahj	356	20	MPV458	MPV458	NNP
cord-342419-liaihahj	356	21	(	(	-LRB-
cord-342419-liaihahj	356	22	B	b	NN
cord-342419-liaihahj	356	23	)	)	-RRB-
cord-342419-liaihahj	356	24	or	or	CC
cord-342419-liaihahj	356	25	MPV465	MPV465	NNP
cord-342419-liaihahj	356	26	(	(	-LRB-
cord-342419-liaihahj	356	27	C	C	NNP
cord-342419-liaihahj	356	28	)	)	-RRB-
cord-342419-liaihahj	356	29	.	.	.
cord-342419-liaihahj	357	1	A	a	DT
cord-342419-liaihahj	357	2	decrease	decrease	NN
cord-342419-liaihahj	357	3	in	in	IN
cord-342419-liaihahj	357	4	signal	signal	NN
cord-342419-liaihahj	357	5	was	be	VBD
cord-342419-liaihahj	357	6	observed	observe	VBN
cord-342419-liaihahj	357	7	when	when	WRB
cord-342419-liaihahj	357	8	attempting	attempt	VBG
cord-342419-liaihahj	357	9	to	to	TO
cord-342419-liaihahj	357	10	load	load	VB
cord-342419-liaihahj	357	11	458	458	CD
cord-342419-liaihahj	357	12	or	or	CC
cord-342419-liaihahj	357	13	465	465	CD
cord-342419-liaihahj	357	14	in	in	IN
cord-342419-liaihahj	357	15	the	the	DT
cord-342419-liaihahj	357	16	presence	presence	NN
cord-342419-liaihahj	357	17	of	of	IN
cord-342419-liaihahj	357	18	biosensors	biosensor	NNS
cord-342419-liaihahj	357	19	already	already	RB
cord-342419-liaihahj	357	20	loaded	load	VBN
cord-342419-liaihahj	357	21	with	with	IN
cord-342419-liaihahj	357	22	MPV458	MPV458	NNP
cord-342419-liaihahj	357	23	or	or	CC
cord-342419-liaihahj	357	24	MPV465	MPV465	NNP
cord-342419-liaihahj	357	25	.	.	.
cord-342419-liaihahj	358	1	No	no	DT
cord-342419-liaihahj	358	2	competition	competition	NN
cord-342419-liaihahj	358	3	between	between	IN
cord-342419-liaihahj	358	4	MPV458	MPV458	NNP
cord-342419-liaihahj	358	5	or	or	CC
cord-342419-liaihahj	358	6	MPV465	MPV465	NNP
cord-342419-liaihahj	358	7	and	and	CC
cord-342419-liaihahj	358	8	other	other	JJ
cord-342419-liaihahj	358	9	control	control	NN
cord-342419-liaihahj	358	10	mAbs	mAbs	NNP
cord-342419-liaihahj	358	11	was	be	VBD
cord-342419-liaihahj	358	12	observed	observe	VBN
cord-342419-liaihahj	358	13	,	,	,
cord-342419-liaihahj	358	14	and	and	CC
cord-342419-liaihahj	358	15	competition	competition	NN
cord-342419-liaihahj	358	16	was	be	VBD
cord-342419-liaihahj	358	17	observed	observe	VBN
cord-342419-liaihahj	358	18	between	between	IN
cord-342419-liaihahj	358	19	MPV458	MPV458	NNP
cord-342419-liaihahj	358	20	and	and	CC
cord-342419-liaihahj	358	21	MPV465	MPV465	NNP
cord-342419-liaihahj	358	22	.	.	.
cord-342419-liaihahj	358	23	 	 	_SP
cord-342419-liaihahj	359	1	A	a	DT
cord-342419-liaihahj	359	2	newly	newly	RB
cord-342419-liaihahj	359	3	discovered	discover	VBN
cord-342419-liaihahj	359	4	human	human	JJ
cord-342419-liaihahj	359	5	pneumovirus	pneumovirus	NNP
cord-342419-liaihahj	359	6	isolated	isolate	VBN
cord-342419-liaihahj	359	7	from	from	IN
cord-342419-liaihahj	359	8	young	young	JJ
cord-342419-liaihahj	359	9	children	child	NNS
cord-342419-liaihahj	359	10	with	with	IN
cord-342419-liaihahj	359	11	respiratory	respiratory	JJ
cord-342419-liaihahj	359	12	tract	tract	NN
cord-342419-liaihahj	359	13	disease	disease	NN
cord-342419-liaihahj	359	14	Human	Human	NNP
cord-342419-liaihahj	359	15	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	359	16	:	:	:
cord-342419-liaihahj	359	17	Review	Review	NNP
cord-342419-liaihahj	359	18	of	of	IN
cord-342419-liaihahj	359	19	an	an	DT
cord-342419-liaihahj	359	20	important	important	JJ
cord-342419-liaihahj	359	21	respiratory	respiratory	JJ
cord-342419-liaihahj	359	22	pathogen	pathogen	NN
cord-342419-liaihahj	359	23	Human	Human	NNP
cord-342419-liaihahj	359	24	metapneumovirus	metapneumovirus	JJ
cord-342419-liaihahj	359	25	infections	infection	NNS
cord-342419-liaihahj	359	26	in	in	IN
cord-342419-liaihahj	359	27	young	young	JJ
cord-342419-liaihahj	359	28	and	and	CC
cord-342419-liaihahj	359	29	elderly	elderly	JJ
cord-342419-liaihahj	359	30	adults	adult	NNS
cord-342419-liaihahj	359	31	Prevalence	prevalence	NN
cord-342419-liaihahj	359	32	and	and	CC
cord-342419-liaihahj	359	33	clinical	clinical	JJ
cord-342419-liaihahj	359	34	symptoms	symptom	NNS
cord-342419-liaihahj	359	35	of	of	IN
cord-342419-liaihahj	359	36	human	human	JJ
cord-342419-liaihahj	359	37	metapneumovirus	metapneumovirus	JJ
cord-342419-liaihahj	359	38	infection	infection	NN
cord-342419-liaihahj	359	39	in	in	IN
cord-342419-liaihahj	359	40	hospitalized	hospitalize	VBN
cord-342419-liaihahj	359	41	patients	patient	NNS
cord-342419-liaihahj	359	42	Human	Human	NNP
cord-342419-liaihahj	359	43	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	359	44	-	-	HYPH
cord-342419-liaihahj	359	45	associated	associate	VBN
cord-342419-liaihahj	359	46	lower	low	JJR
cord-342419-liaihahj	359	47	respiratory	respiratory	JJ
cord-342419-liaihahj	359	48	tract	tract	NN
cord-342419-liaihahj	359	49	infections	infection	NNS
cord-342419-liaihahj	359	50	among	among	IN
cord-342419-liaihahj	359	51	hospitalized	hospitalize	VBN
cord-342419-liaihahj	359	52	human	human	JJ
cord-342419-liaihahj	359	53	immunodeficiency	immunodeficiency	NN
cord-342419-liaihahj	359	54	virus	virus	NN
cord-342419-liaihahj	359	55	type	type	NN
cord-342419-liaihahj	359	56	1	1	CD
cord-342419-liaihahj	359	57	(	(	-LRB-
cord-342419-liaihahj	359	58	HIV-1)-infected	hiv-1)-infected	JJ
cord-342419-liaihahj	359	59	and	and	CC
cord-342419-liaihahj	359	60	HIV-1-uninfected	hiv-1-uninfecte	VBN
cord-342419-liaihahj	359	61	African	african	JJ
cord-342419-liaihahj	359	62	infants	infant	NNS
cord-342419-liaihahj	359	63	Human	Human	NNP
cord-342419-liaihahj	359	64	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	359	65	in	in	IN
cord-342419-liaihahj	359	66	adults	adult	NNS
cord-342419-liaihahj	359	67	Human	human	JJ
cord-342419-liaihahj	359	68	metapneumovirus	metapneumovirus	JJ
cord-342419-liaihahj	359	69	infection	infection	NN
cord-342419-liaihahj	359	70	in	in	IN
cord-342419-liaihahj	359	71	lung	lung	NN
cord-342419-liaihahj	359	72	transplant	transplant	NN
cord-342419-liaihahj	359	73	recipients	recipient	NNS
cord-342419-liaihahj	359	74	:	:	:
cord-342419-liaihahj	359	75	Clinical	clinical	JJ
cord-342419-liaihahj	359	76	presentation	presentation	NN
cord-342419-liaihahj	359	77	and	and	CC
cord-342419-liaihahj	359	78	epidemiology	epidemiology	NN
cord-342419-liaihahj	359	79	Human	Human	NNP
cord-342419-liaihahj	359	80	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	359	81	in	in	IN
cord-342419-liaihahj	359	82	a	a	DT
cord-342419-liaihahj	359	83	haematopoietic	haematopoietic	JJ
cord-342419-liaihahj	359	84	stem	stem	NN
cord-342419-liaihahj	359	85	cell	cell	NN
cord-342419-liaihahj	359	86	transplant	transplant	NN
cord-342419-liaihahj	359	87	recipient	recipient	NN
cord-342419-liaihahj	359	88	with	with	IN
cord-342419-liaihahj	359	89	fatal	fatal	JJ
cord-342419-liaihahj	359	90	lower	low	JJR
cord-342419-liaihahj	359	91	respiratory	respiratory	JJ
cord-342419-liaihahj	359	92	tract	tract	NN
cord-342419-liaihahj	359	93	disease	disease	NN
cord-342419-liaihahj	359	94	Fatal	fatal	JJ
cord-342419-liaihahj	359	95	human	human	JJ
cord-342419-liaihahj	359	96	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	359	97	infection	infection	NN
cord-342419-liaihahj	359	98	following	follow	VBG
cord-342419-liaihahj	359	99	allogeneic	allogeneic	FW
cord-342419-liaihahj	359	100	hematopoietic	hematopoietic	JJ
cord-342419-liaihahj	359	101	stem	stem	NN
cord-342419-liaihahj	359	102	cell	cell	NN
cord-342419-liaihahj	359	103	transplantation	transplantation	NN
cord-342419-liaihahj	359	104	Human	Human	NNP
cord-342419-liaihahj	359	105	metapneumovirus	metapneumovirus	JJ
cord-342419-liaihahj	359	106	infections	infection	NNS
cord-342419-liaihahj	359	107	in	in	IN
cord-342419-liaihahj	359	108	hematopoietic	hematopoietic	JJ
cord-342419-liaihahj	359	109	cell	cell	NN
cord-342419-liaihahj	359	110	transplant	transplant	NN
cord-342419-liaihahj	359	111	recipients	recipient	NNS
cord-342419-liaihahj	359	112	and	and	CC
cord-342419-liaihahj	359	113	hematologic	hematologic	JJ
cord-342419-liaihahj	359	114	malignancy	malignancy	NN
cord-342419-liaihahj	359	115	patients	patient	NNS
cord-342419-liaihahj	359	116	:	:	:
cord-342419-liaihahj	360	1	A	a	DT
cord-342419-liaihahj	360	2	systematic	systematic	JJ
cord-342419-liaihahj	360	3	review	review	NN
cord-342419-liaihahj	360	4	Human	human	JJ
cord-342419-liaihahj	360	5	metapneumovirus	metapneumovirus	JJ
cord-342419-liaihahj	360	6	infection	infection	NN
cord-342419-liaihahj	360	7	in	in	IN
cord-342419-liaihahj	360	8	a	a	DT
cord-342419-liaihahj	360	9	hematopoietic	hematopoietic	JJ
cord-342419-liaihahj	360	10	stem	stem	NN
cord-342419-liaihahj	360	11	cell	cell	NN
cord-342419-liaihahj	360	12	transplant	transplant	NN
cord-342419-liaihahj	360	13	recipient	recipient	NN
cord-342419-liaihahj	360	14	with	with	IN
cord-342419-liaihahj	360	15	relapsed	relapse	VBN
cord-342419-liaihahj	360	16	multiple	multiple	JJ
cord-342419-liaihahj	360	17	myeloma	myeloma	NN
cord-342419-liaihahj	360	18	and	and	CC
cord-342419-liaihahj	360	19	rapidly	rapidly	RB
cord-342419-liaihahj	360	20	progressing	progress	VBG
cord-342419-liaihahj	360	21	lung	lung	NN
cord-342419-liaihahj	360	22	cancer	cancer	NN
cord-342419-liaihahj	360	23	Fatal	Fatal	NNP
cord-342419-liaihahj	360	24	human	human	JJ
cord-342419-liaihahj	360	25	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	360	26	infection	infection	NN
cord-342419-liaihahj	360	27	following	follow	VBG
cord-342419-liaihahj	360	28	allogeneic	allogeneic	FW
cord-342419-liaihahj	360	29	hematopoietic	hematopoietic	JJ
cord-342419-liaihahj	360	30	stem	stem	NN
cord-342419-liaihahj	360	31	cell	cell	NN
cord-342419-liaihahj	360	32	transplantation	transplantation	NN
cord-342419-liaihahj	360	33	Severe	severe	JJ
cord-342419-liaihahj	360	34	respiratory	respiratory	JJ
cord-342419-liaihahj	360	35	illness	illness	NN
cord-342419-liaihahj	360	36	associated	associate	VBN
cord-342419-liaihahj	360	37	with	with	IN
cord-342419-liaihahj	360	38	human	human	JJ
cord-342419-liaihahj	360	39	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	360	40	in	in	IN
cord-342419-liaihahj	360	41	nursing	nursing	NN
cord-342419-liaihahj	360	42	home	home	NN
cord-342419-liaihahj	360	43	Outbreak	outbreak	NN
cord-342419-liaihahj	360	44	of	of	IN
cord-342419-liaihahj	360	45	Human	Human	NNP
cord-342419-liaihahj	360	46	Metapneumovirus	Metapneumovirus	NNP
cord-342419-liaihahj	360	47	in	in	IN
cord-342419-liaihahj	360	48	a	a	DT
cord-342419-liaihahj	360	49	Nursing	Nursing	NNP
cord-342419-liaihahj	360	50	Home	home	NN
cord-342419-liaihahj	360	51	:	:	:
cord-342419-liaihahj	360	52	A	a	DT
cord-342419-liaihahj	360	53	Clinical	clinical	JJ
cord-342419-liaihahj	360	54	Perspective	perspective	NN
cord-342419-liaihahj	360	55	Outbreaks	outbreak	NNS
cord-342419-liaihahj	360	56	of	of	IN
cord-342419-liaihahj	360	57	human	human	JJ
cord-342419-liaihahj	360	58	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	360	59	in	in	IN
cord-342419-liaihahj	360	60	two	two	CD
cord-342419-liaihahj	360	61	skilled	skilled	JJ
cord-342419-liaihahj	360	62	nursing	nursing	NN
cord-342419-liaihahj	360	63	facilities	facility	NNS
cord-342419-liaihahj	360	64	-West	-West	NNP
cord-342419-liaihahj	360	65	Virginia	Virginia	NNP
cord-342419-liaihahj	360	66	and	and	CC
cord-342419-liaihahj	360	67	Idaho	Idaho	NNP
cord-342419-liaihahj	360	68	Epidemiological	Epidemiological	NNP
cord-342419-liaihahj	360	69	survey	survey	NN
cord-342419-liaihahj	360	70	in	in	IN
cord-342419-liaihahj	360	71	a	a	DT
cord-342419-liaihahj	360	72	day	day	NN
cord-342419-liaihahj	360	73	care	care	NN
cord-342419-liaihahj	360	74	center	center	NN
cord-342419-liaihahj	360	75	following	follow	VBG
cord-342419-liaihahj	360	76	toddler	toddler	NN
cord-342419-liaihahj	360	77	sudden	sudden	JJ
cord-342419-liaihahj	360	78	death	death	NN
cord-342419-liaihahj	360	79	due	due	IN
cord-342419-liaihahj	360	80	to	to	IN
cord-342419-liaihahj	360	81	human	human	JJ
cord-342419-liaihahj	360	82	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	360	83	infection	infection	NN
cord-342419-liaihahj	360	84	Viral	viral	JJ
cord-342419-liaihahj	360	85	pathogens	pathogen	NNS
cord-342419-liaihahj	360	86	including	include	VBG
cord-342419-liaihahj	360	87	human	human	JJ
cord-342419-liaihahj	360	88	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	360	89	are	be	VBP
cord-342419-liaihahj	360	90	the	the	DT
cord-342419-liaihahj	360	91	primary	primary	JJ
cord-342419-liaihahj	360	92	cause	cause	NN
cord-342419-liaihahj	360	93	of	of	IN
cord-342419-liaihahj	360	94	febrile	febrile	JJ
cord-342419-liaihahj	360	95	respiratory	respiratory	JJ
cord-342419-liaihahj	360	96	illness	illness	NN
cord-342419-liaihahj	360	97	in	in	IN
cord-342419-liaihahj	360	98	HIV	HIV	NNP
cord-342419-liaihahj	360	99	-	-	HYPH
cord-342419-liaihahj	360	100	infected	infect	VBN
cord-342419-liaihahj	360	101	adults	adult	NNS
cord-342419-liaihahj	360	102	receiving	receive	VBG
cord-342419-liaihahj	360	103	antiretroviral	antiretroviral	JJ
cord-342419-liaihahj	360	104	therapy	therapy	NN
cord-342419-liaihahj	360	105	Human	Human	NNP
cord-342419-liaihahj	360	106	metapneumovirus	metapneumovirus	JJ
cord-342419-liaihahj	360	107	infection	infection	NN
cord-342419-liaihahj	360	108	in	in	IN
cord-342419-liaihahj	360	109	chronic	chronic	JJ
cord-342419-liaihahj	360	110	obstructive	obstructive	JJ
cord-342419-liaihahj	360	111	pulmonary	pulmonary	JJ
cord-342419-liaihahj	360	112	disease	disease	NN
cord-342419-liaihahj	360	113	:	:	:
cord-342419-liaihahj	360	114	Impact	impact	NN
cord-342419-liaihahj	360	115	of	of	IN
cord-342419-liaihahj	360	116	glucocorticosteroids	glucocorticosteroid	NNS
cord-342419-liaihahj	360	117	and	and	CC
cord-342419-liaihahj	360	118	interferon	interferon	NNP
cord-342419-liaihahj	360	119	Human	Human	NNP
cord-342419-liaihahj	360	120	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	360	121	-	-	HYPH
cord-342419-liaihahj	360	122	associated	associate	VBN
cord-342419-liaihahj	360	123	atypical	atypical	JJ
cord-342419-liaihahj	360	124	pneumonia	pneumonia	NN
cord-342419-liaihahj	360	125	and	and	CC
cord-342419-liaihahj	360	126	SARS	SARS	NNP
cord-342419-liaihahj	360	127	Co	Co	NNP
cord-342419-liaihahj	360	128	-	-	NN
cord-342419-liaihahj	360	129	circulation	circulation	NN
cord-342419-liaihahj	360	130	of	of	IN
cord-342419-liaihahj	360	131	human	human	JJ
cord-342419-liaihahj	360	132	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	360	133	and	and	CC
cord-342419-liaihahj	360	134	SARS	SARS	NNP
cord-342419-liaihahj	360	135	-	-	HYPH
cord-342419-liaihahj	360	136	associated	associate	VBN
cord-342419-liaihahj	360	137	coronavirus	coronavirus	NN
cord-342419-liaihahj	360	138	during	during	IN
cord-342419-liaihahj	360	139	a	a	DT
cord-342419-liaihahj	360	140	major	major	JJ
cord-342419-liaihahj	360	141	nosocomial	nosocomial	JJ
cord-342419-liaihahj	360	142	SARS	SARS	NNP
cord-342419-liaihahj	360	143	outbreak	outbreak	NN
cord-342419-liaihahj	360	144	in	in	IN
cord-342419-liaihahj	360	145	Hong	Hong	NNP
cord-342419-liaihahj	360	146	Kong	Kong	NNP
cord-342419-liaihahj	360	147	Human	Human	NNP
cord-342419-liaihahj	360	148	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	360	149	detection	detection	NN
cord-342419-liaihahj	360	150	in	in	IN
cord-342419-liaihahj	360	151	patients	patient	NNS
cord-342419-liaihahj	360	152	with	with	IN
cord-342419-liaihahj	360	153	severe	severe	JJ
cord-342419-liaihahj	360	154	acute	acute	JJ
cord-342419-liaihahj	360	155	respiratory	respiratory	JJ
cord-342419-liaihahj	360	156	syndrome	syndrome	NN
cord-342419-liaihahj	360	157	Report	report	NN
cord-342419-liaihahj	360	158	of	of	IN
cord-342419-liaihahj	360	159	death	death	NN
cord-342419-liaihahj	360	160	in	in	IN
cord-342419-liaihahj	360	161	children	child	NNS
cord-342419-liaihahj	360	162	with	with	IN
cord-342419-liaihahj	360	163	SARS	SARS	NNP
cord-342419-liaihahj	360	164	-	-	HYPH
cord-342419-liaihahj	360	165	CoV-2	CoV-2	NNP
cord-342419-liaihahj	360	166	and	and	CC
cord-342419-liaihahj	360	167	Human	Human	NNP
cord-342419-liaihahj	360	168	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	360	169	(	(	-LRB-
cord-342419-liaihahj	360	170	hMPV	hmpv	NN
cord-342419-liaihahj	360	171	)	)	-RRB-
cord-342419-liaihahj	360	172	co	co	NNS
cord-342419-liaihahj	360	173	-	-	NN
cord-342419-liaihahj	360	174	infection	infection	NN
cord-342419-liaihahj	360	175	:	:	:
cord-342419-liaihahj	360	176	is	be	VBZ
cord-342419-liaihahj	360	177	hMPV	hMPV	NNP
cord-342419-liaihahj	361	1	the	the	DT
cord-342419-liaihahj	361	2	trigger	trigger	NN
cord-342419-liaihahj	361	3	Integrin	Integrin	NNP
cord-342419-liaihahj	361	4	alphavbeta1	alphavbeta1	NN
cord-342419-liaihahj	361	5	promotes	promote	VBZ
cord-342419-liaihahj	361	6	infection	infection	NN
cord-342419-liaihahj	361	7	by	by	IN
cord-342419-liaihahj	361	8	human	human	JJ
cord-342419-liaihahj	361	9	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	362	1	The	the	DT
cord-342419-liaihahj	362	2	human	human	JJ
cord-342419-liaihahj	362	3	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	362	4	fusion	fusion	NN
cord-342419-liaihahj	362	5	protein	protein	NN
cord-342419-liaihahj	362	6	mediates	mediate	VBZ
cord-342419-liaihahj	362	7	entry	entry	NN
cord-342419-liaihahj	362	8	via	via	IN
cord-342419-liaihahj	362	9	an	an	DT
cord-342419-liaihahj	362	10	interaction	interaction	NN
cord-342419-liaihahj	362	11	with	with	IN
cord-342419-liaihahj	362	12	RGD	RGD	NNP
cord-342419-liaihahj	362	13	-	-	HYPH
cord-342419-liaihahj	362	14	binding	bind	VBG
cord-342419-liaihahj	362	15	integrins	integrins	NNP
cord-342419-liaihahj	362	16	Human	Human	NNP
cord-342419-liaihahj	362	17	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	363	1	Is	be	VBZ
cord-342419-liaihahj	363	2	capable	capable	JJ
cord-342419-liaihahj	363	3	of	of	IN
cord-342419-liaihahj	363	4	entering	enter	VBG
cord-342419-liaihahj	363	5	cells	cell	NNS
cord-342419-liaihahj	363	6	by	by	IN
cord-342419-liaihahj	363	7	fusion	fusion	NN
cord-342419-liaihahj	363	8	with	with	IN
cord-342419-liaihahj	363	9	endosomal	endosomal	NNP
cord-342419-liaihahj	363	10	membranes	membrane	NNS
cord-342419-liaihahj	363	11	Antibody	Antibody	NNP
cord-342419-liaihahj	363	12	Epitopes	Epitopes	NNP
cord-342419-liaihahj	363	13	of	of	IN
cord-342419-liaihahj	363	14	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	363	15	Fusion	Fusion	NNP
cord-342419-liaihahj	363	16	Proteins	Proteins	NNP
cord-342419-liaihahj	363	17	Recombinant	Recombinant	NNP
cord-342419-liaihahj	363	18	human	human	NN
cord-342419-liaihahj	363	19	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	363	20	lacking	lack	VBG
cord-342419-liaihahj	363	21	the	the	DT
cord-342419-liaihahj	363	22	small	small	JJ
cord-342419-liaihahj	363	23	hydrophobic	hydrophobic	JJ
cord-342419-liaihahj	363	24	SH	sh	NN
cord-342419-liaihahj	364	1	and/or	and/or	CC
cord-342419-liaihahj	365	1	attachment	attachment	NNP
cord-342419-liaihahj	365	2	G	G	NNP
cord-342419-liaihahj	365	3	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	365	4	:	:	:
cord-342419-liaihahj	366	1	Deletion	deletion	NN
cord-342419-liaihahj	366	2	of	of	IN
cord-342419-liaihahj	366	3	G	g	NN
cord-342419-liaihahj	366	4	yields	yield	NNS
cord-342419-liaihahj	366	5	a	a	DT
cord-342419-liaihahj	366	6	promising	promising	JJ
cord-342419-liaihahj	366	7	vaccine	vaccine	NN
cord-342419-liaihahj	366	8	candidate	candidate	NN
cord-342419-liaihahj	366	9	Humoral	Humoral	NNP
cord-342419-liaihahj	366	10	response	response	NN
cord-342419-liaihahj	366	11	to	to	IN
cord-342419-liaihahj	366	12	the	the	DT
cord-342419-liaihahj	366	13	central	central	JJ
cord-342419-liaihahj	366	14	unglycosylated	unglycosylated	JJ
cord-342419-liaihahj	366	15	region	region	NN
cord-342419-liaihahj	366	16	of	of	IN
cord-342419-liaihahj	366	17	the	the	DT
cord-342419-liaihahj	366	18	respiratory	respiratory	JJ
cord-342419-liaihahj	366	19	syncytial	syncytial	JJ
cord-342419-liaihahj	366	20	virus	virus	NN
cord-342419-liaihahj	366	21	attachment	attachment	NN
cord-342419-liaihahj	366	22	protein	protein	NN
cord-342419-liaihahj	366	23	Structure	Structure	NNP
cord-342419-liaihahj	366	24	and	and	CC
cord-342419-liaihahj	366	25	immunogenicity	immunogenicity	NN
cord-342419-liaihahj	366	26	of	of	IN
cord-342419-liaihahj	366	27	pre	pre	JJ
cord-342419-liaihahj	366	28	-	-	JJ
cord-342419-liaihahj	366	29	fusion	fusion	NN
cord-342419-liaihahj	366	30	-	-	HYPH
cord-342419-liaihahj	366	31	stabilized	stabilize	VBN
cord-342419-liaihahj	366	32	human	human	NN
cord-342419-liaihahj	366	33	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	366	34	F	F	NNP
cord-342419-liaihahj	366	35	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	366	36	Structure	Structure	NNP
cord-342419-liaihahj	366	37	-	-	HYPH
cord-342419-liaihahj	366	38	based	base	VBN
cord-342419-liaihahj	366	39	design	design	NN
cord-342419-liaihahj	366	40	of	of	IN
cord-342419-liaihahj	366	41	a	a	DT
cord-342419-liaihahj	366	42	fusion	fusion	NN
cord-342419-liaihahj	366	43	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	366	44	vaccine	vaccine	NN
cord-342419-liaihahj	366	45	for	for	IN
cord-342419-liaihahj	366	46	respiratory	respiratory	JJ
cord-342419-liaihahj	366	47	syncytial	syncytial	JJ
cord-342419-liaihahj	366	48	virus	virus	NN
cord-342419-liaihahj	366	49	A	a	DT
cord-342419-liaihahj	366	50	highly	highly	RB
cord-342419-liaihahj	366	51	stable	stable	JJ
cord-342419-liaihahj	366	52	prefusion	prefusion	NN
cord-342419-liaihahj	366	53	RSV	RSV	NNP
cord-342419-liaihahj	366	54	F	F	NNP
cord-342419-liaihahj	366	55	vaccine	vaccine	NN
cord-342419-liaihahj	366	56	derived	derive	VBN
cord-342419-liaihahj	366	57	from	from	IN
cord-342419-liaihahj	366	58	structural	structural	JJ
cord-342419-liaihahj	366	59	analysis	analysis	NN
cord-342419-liaihahj	366	60	of	of	IN
cord-342419-liaihahj	366	61	the	the	DT
cord-342419-liaihahj	366	62	fusion	fusion	NN
cord-342419-liaihahj	366	63	mechanism	mechanism	NN
cord-342419-liaihahj	367	1	A	a	DT
cord-342419-liaihahj	367	2	proof	proof	NN
cord-342419-liaihahj	367	3	of	of	IN
cord-342419-liaihahj	367	4	concept	concept	NN
cord-342419-liaihahj	367	5	for	for	IN
cord-342419-liaihahj	367	6	structure	structure	NN
cord-342419-liaihahj	367	7	-	-	HYPH
cord-342419-liaihahj	367	8	based	base	VBN
cord-342419-liaihahj	367	9	vaccine	vaccine	NN
cord-342419-liaihahj	367	10	design	design	NN
cord-342419-liaihahj	367	11	targeting	target	VBG
cord-342419-liaihahj	367	12	RSV	RSV	NNP
cord-342419-liaihahj	367	13	in	in	IN
cord-342419-liaihahj	367	14	humans	human	NNS
cord-342419-liaihahj	367	15	Characterization	characterization	NN
cord-342419-liaihahj	367	16	of	of	IN
cord-342419-liaihahj	367	17	human	human	JJ
cord-342419-liaihahj	367	18	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	367	19	F	F	NNP
cord-342419-liaihahj	367	20	protein	protein	NN
cord-342419-liaihahj	367	21	-	-	HYPH
cord-342419-liaihahj	367	22	promoted	promote	VBN
cord-342419-liaihahj	367	23	membrane	membrane	NN
cord-342419-liaihahj	367	24	fusion	fusion	NN
cord-342419-liaihahj	367	25	:	:	:
cord-342419-liaihahj	367	26	critical	critical	JJ
cord-342419-liaihahj	367	27	roles	role	NNS
cord-342419-liaihahj	367	28	for	for	IN
cord-342419-liaihahj	367	29	proteolytic	proteolytic	JJ
cord-342419-liaihahj	367	30	processing	processing	NN
cord-342419-liaihahj	367	31	and	and	CC
cord-342419-liaihahj	367	32	low	low	JJ
cord-342419-liaihahj	367	33	pH	pH	NNP
cord-342419-liaihahj	367	34	Engineering	Engineering	NNP
cord-342419-liaihahj	367	35	,	,	,
cord-342419-liaihahj	367	36	structure	structure	NN
cord-342419-liaihahj	367	37	and	and	CC
cord-342419-liaihahj	367	38	immunogenicity	immunogenicity	NN
cord-342419-liaihahj	367	39	of	of	IN
cord-342419-liaihahj	367	40	the	the	DT
cord-342419-liaihahj	367	41	human	human	JJ
cord-342419-liaihahj	367	42	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	367	43	F	F	NNP
cord-342419-liaihahj	367	44	protein	protein	NN
cord-342419-liaihahj	367	45	in	in	IN
cord-342419-liaihahj	367	46	the	the	DT
cord-342419-liaihahj	367	47	postfusion	postfusion	NN
cord-342419-liaihahj	367	48	conformation	conformation	NN
cord-342419-liaihahj	367	49	Rapid	Rapid	NNP
cord-342419-liaihahj	367	50	profiling	profiling	NN
cord-342419-liaihahj	367	51	of	of	IN
cord-342419-liaihahj	367	52	RSV	RSV	NNP
cord-342419-liaihahj	367	53	antibody	antibody	NN
cord-342419-liaihahj	367	54	repertoires	repertoire	NNS
cord-342419-liaihahj	367	55	from	from	IN
cord-342419-liaihahj	367	56	the	the	DT
cord-342419-liaihahj	367	57	memory	memory	NN
cord-342419-liaihahj	367	58	B	b	NN
cord-342419-liaihahj	367	59	cells	cell	NNS
cord-342419-liaihahj	367	60	of	of	IN
cord-342419-liaihahj	367	61	naturally	naturally	RB
cord-342419-liaihahj	367	62	infected	infect	VBN
cord-342419-liaihahj	367	63	adult	adult	NN
cord-342419-liaihahj	367	64	donors	donor	NNS
cord-342419-liaihahj	367	65	A	a	DT
cord-342419-liaihahj	367	66	novel	novel	JJ
cord-342419-liaihahj	367	67	pre	pre	JJ
cord-342419-liaihahj	367	68	-	-	JJ
cord-342419-liaihahj	367	69	fusion	fusion	JJ
cord-342419-liaihahj	367	70	conformation	conformation	NN
cord-342419-liaihahj	367	71	-	-	HYPH
cord-342419-liaihahj	367	72	specific	specific	JJ
cord-342419-liaihahj	367	73	neutralizing	neutralize	VBG
cord-342419-liaihahj	367	74	epitope	epitope	NN
cord-342419-liaihahj	367	75	on	on	IN
cord-342419-liaihahj	367	76	the	the	DT
cord-342419-liaihahj	367	77	respiratory	respiratory	JJ
cord-342419-liaihahj	367	78	syncytial	syncytial	JJ
cord-342419-liaihahj	367	79	virus	virus	NN
cord-342419-liaihahj	367	80	fusion	fusion	NN
cord-342419-liaihahj	367	81	protein	protein	NN
cord-342419-liaihahj	367	82	Prefusion	Prefusion	NNP
cord-342419-liaihahj	367	83	F	F	NNP
cord-342419-liaihahj	367	84	-	-	HYPH
cord-342419-liaihahj	367	85	specific	specific	JJ
cord-342419-liaihahj	367	86	antibodies	antibody	NNS
cord-342419-liaihahj	367	87	determine	determine	VBP
cord-342419-liaihahj	367	88	the	the	DT
cord-342419-liaihahj	367	89	magnitude	magnitude	NN
cord-342419-liaihahj	367	90	of	of	IN
cord-342419-liaihahj	367	91	RSV	RSV	NNP
cord-342419-liaihahj	367	92	neutralizing	neutralize	VBG
cord-342419-liaihahj	367	93	activity	activity	NN
cord-342419-liaihahj	367	94	in	in	IN
cord-342419-liaihahj	367	95	human	human	JJ
cord-342419-liaihahj	367	96	sera	sera	NNP
cord-342419-liaihahj	367	97	Isolation	Isolation	NNP
cord-342419-liaihahj	367	98	and	and	CC
cord-342419-liaihahj	367	99	characterization	characterization	NN
cord-342419-liaihahj	367	100	of	of	IN
cord-342419-liaihahj	367	101	monoclonal	monoclonal	JJ
cord-342419-liaihahj	367	102	antibodies	antibody	NNS
cord-342419-liaihahj	367	103	which	which	WDT
cord-342419-liaihahj	367	104	neutralize	neutralize	VBP
cord-342419-liaihahj	367	105	human	human	JJ
cord-342419-liaihahj	367	106	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	367	107	in	in	IN
cord-342419-liaihahj	367	108	vitro	vitro	FW
cord-342419-liaihahj	367	109	and	and	CC
cord-342419-liaihahj	367	110	in	in	IN
cord-342419-liaihahj	367	111	vivo	vivo	NNP
cord-342419-liaihahj	367	112	Identification	identification	NN
cord-342419-liaihahj	367	113	of	of	IN
cord-342419-liaihahj	367	114	antibody	antibody	NN
cord-342419-liaihahj	367	115	neutralization	neutralization	NN
cord-342419-liaihahj	367	116	epitopes	epitope	NNS
cord-342419-liaihahj	367	117	on	on	IN
cord-342419-liaihahj	367	118	the	the	DT
cord-342419-liaihahj	367	119	fusion	fusion	NN
cord-342419-liaihahj	367	120	protein	protein	NN
cord-342419-liaihahj	367	121	of	of	IN
cord-342419-liaihahj	367	122	human	human	JJ
cord-342419-liaihahj	367	123	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	367	124	A	A	NNP
cord-342419-liaihahj	367	125	recombinant	recombinant	JJ
cord-342419-liaihahj	367	126	human	human	JJ
cord-342419-liaihahj	367	127	monoclonal	monoclonal	JJ
cord-342419-liaihahj	367	128	antibody	antibody	NN
cord-342419-liaihahj	367	129	to	to	IN
cord-342419-liaihahj	367	130	human	human	JJ
cord-342419-liaihahj	367	131	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	367	132	fusion	fusion	NN
cord-342419-liaihahj	367	133	protein	protein	NN
cord-342419-liaihahj	367	134	that	that	WDT
cord-342419-liaihahj	367	135	neutralizes	neutralize	VBZ
cord-342419-liaihahj	367	136	virus	virus	NN
cord-342419-liaihahj	367	137	in	in	IN
cord-342419-liaihahj	367	138	vitro	vitro	FW
cord-342419-liaihahj	367	139	and	and	CC
cord-342419-liaihahj	367	140	is	be	VBZ
cord-342419-liaihahj	367	141	effective	effective	JJ
cord-342419-liaihahj	367	142	therapeutically	therapeutically	RB
cord-342419-liaihahj	367	143	in	in	IN
cord-342419-liaihahj	367	144	vivo	vivo	NN
cord-342419-liaihahj	368	1	A	a	DT
cord-342419-liaihahj	368	2	broadly	broadly	RB
cord-342419-liaihahj	368	3	neutralizing	neutralize	VBG
cord-342419-liaihahj	368	4	human	human	JJ
cord-342419-liaihahj	368	5	monoclonal	monoclonal	JJ
cord-342419-liaihahj	368	6	antibody	antibody	NN
cord-342419-liaihahj	368	7	exhibits	exhibit	VBZ
cord-342419-liaihahj	368	8	in	in	IN
cord-342419-liaihahj	368	9	vivo	vivo	NN
cord-342419-liaihahj	368	10	efficacy	efficacy	NN
cord-342419-liaihahj	368	11	against	against	IN
cord-342419-liaihahj	368	12	both	both	DT
cord-342419-liaihahj	368	13	human	human	JJ
cord-342419-liaihahj	368	14	metapneumovirus	metapneumovirus	NN
cord-342419-liaihahj	368	15	and	and	CC
cord-342419-liaihahj	368	16	respiratory	respiratory	JJ
cord-342419-liaihahj	368	17	syncytial	syncytial	JJ
cord-342419-liaihahj	368	18	virus	virus	NN
cord-342419-liaihahj	368	19	Cross	cross	NN
cord-342419-liaihahj	368	20	-	-	NN
cord-342419-liaihahj	368	21	neutralization	neutralization	NN
cord-342419-liaihahj	368	22	of	of	IN
cord-342419-liaihahj	368	23	four	four	CD
cord-342419-liaihahj	368	24	paramyxoviruses	paramyxovirus	NNS
cord-342419-liaihahj	368	25	by	by	IN
cord-342419-liaihahj	368	26	a	a	DT
cord-342419-liaihahj	368	27	human	human	JJ
cord-342419-liaihahj	368	28	monoclonal	monoclonal	JJ
cord-342419-liaihahj	368	29	antibody	antibody	NN
cord-342419-liaihahj	368	30	Structural	structural	JJ
cord-342419-liaihahj	368	31	basis	basis	NN
cord-342419-liaihahj	368	32	for	for	IN
cord-342419-liaihahj	368	33	antibody	antibody	NN
cord-342419-liaihahj	368	34	crossneutralization	crossneutralization	NN
cord-342419-liaihahj	368	35	of	of	IN
cord-342419-liaihahj	368	36	respiratory	respiratory	JJ
cord-342419-liaihahj	368	37	syncytial	syncytial	JJ
cord-342419-liaihahj	368	38	virus	virus	NN
cord-342419-liaihahj	368	39	and	and	CC
cord-342419-liaihahj	368	40	human	human	JJ
cord-342419-liaihahj	368	41	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	368	42	Human	Human	NNP
cord-342419-liaihahj	368	43	antibody	antibody	NN
cord-342419-liaihahj	368	44	recognition	recognition	NN
cord-342419-liaihahj	368	45	of	of	IN
cord-342419-liaihahj	368	46	antigenic	antigenic	JJ
cord-342419-liaihahj	368	47	site	site	NN
cord-342419-liaihahj	368	48	IV	IV	NNP
cord-342419-liaihahj	368	49	on	on	IN
cord-342419-liaihahj	368	50	Pneumovirus	Pneumovirus	NNP
cord-342419-liaihahj	368	51	fusion	fusion	NN
cord-342419-liaihahj	368	52	proteins	protein	NNS
cord-342419-liaihahj	369	1	A	a	DT
cord-342419-liaihahj	369	2	potent	potent	JJ
cord-342419-liaihahj	369	3	neutralizing	neutralize	VBG
cord-342419-liaihahj	369	4	site	site	NN
cord-342419-liaihahj	369	5	IIIspecific	IIIspecific	NNP
cord-342419-liaihahj	369	6	human	human	JJ
cord-342419-liaihahj	369	7	antibody	antibody	NN
cord-342419-liaihahj	369	8	neutralizes	neutralize	VBZ
cord-342419-liaihahj	369	9	human	human	JJ
cord-342419-liaihahj	369	10	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	369	11	in	in	IN
cord-342419-liaihahj	369	12	vivo	vivo	NNP
cord-342419-liaihahj	369	13	Structure	Structure	NNP
cord-342419-liaihahj	369	14	of	of	IN
cord-342419-liaihahj	369	15	the	the	DT
cord-342419-liaihahj	369	16	human	human	JJ
cord-342419-liaihahj	369	17	metapneumovirus	metapneumovirus	NNP
cord-342419-liaihahj	369	18	fusion	fusion	NN
cord-342419-liaihahj	369	19	protein	protein	NN
cord-342419-liaihahj	369	20	with	with	IN
cord-342419-liaihahj	369	21	neutralizing	neutralize	VBG
cord-342419-liaihahj	369	22	antibody	antibody	NN
cord-342419-liaihahj	369	23	identifies	identify	VBZ
cord-342419-liaihahj	369	24	a	a	DT
cord-342419-liaihahj	369	25	pneumovirus	pneumovirus	NNP
cord-342419-liaihahj	369	26	antigenic	antigenic	JJ
cord-342419-liaihahj	369	27	site	site	NN
cord-342419-liaihahj	369	28	Use	Use	NNP
cord-342419-liaihahj	369	29	of	of	IN
cord-342419-liaihahj	369	30	human	human	JJ
cord-342419-liaihahj	369	31	hybridoma	hybridoma	NN
cord-342419-liaihahj	369	32	technology	technology	NN
cord-342419-liaihahj	369	33	to	to	TO
cord-342419-liaihahj	369	34	isolate	isolate	VB
cord-342419-liaihahj	369	35	human	human	JJ
cord-342419-liaihahj	369	36	monoclonal	monoclonal	JJ
cord-342419-liaihahj	369	37	antibodies	antibody	NNS
cord-342419-liaihahj	369	38	High	high	JJ
cord-342419-liaihahj	369	39	Seroprevalence	Seroprevalence	NNP
cord-342419-liaihahj	369	40	of	of	IN
cord-342419-liaihahj	369	41	Neutralizing	Neutralizing	NNP
cord-342419-liaihahj	369	42	Capacity	Capacity	NNP
cord-342419-liaihahj	369	43	against	against	IN
cord-342419-liaihahj	369	44	Human	Human	NNP
cord-342419-liaihahj	369	45	Metapneumovirus	Metapneumovirus	NNP
cord-342419-liaihahj	369	46	in	in	IN
cord-342419-liaihahj	369	47	All	all	DT
cord-342419-liaihahj	369	48	Age	Age	NNP
cord-342419-liaihahj	369	49	Groups	Groups	NNPS
cord-342419-liaihahj	369	50	Studied	study	VBD
cord-342419-liaihahj	369	51	in	in	IN
cord-342419-liaihahj	369	52	Bonn	Bonn	NNP
cord-342419-liaihahj	369	53	Structural	structural	JJ
cord-342419-liaihahj	369	54	basis	basis	NN
cord-342419-liaihahj	369	55	for	for	IN
cord-342419-liaihahj	369	56	nonneutralizing	nonneutralize	VBG
cord-342419-liaihahj	369	57	antibody	antibody	NN
cord-342419-liaihahj	369	58	competition	competition	NN
cord-342419-liaihahj	369	59	at	at	IN
cord-342419-liaihahj	369	60	antigenic	antigenic	JJ
cord-342419-liaihahj	369	61	site	site	NN
cord-342419-liaihahj	369	62	II	ii	CD
cord-342419-liaihahj	369	63	of	of	IN
cord-342419-liaihahj	369	64	the	the	DT
cord-342419-liaihahj	369	65	respiratory	respiratory	JJ
cord-342419-liaihahj	369	66	syncytial	syncytial	JJ
cord-342419-liaihahj	369	67	virus	virus	NN
cord-342419-liaihahj	369	68	fusion	fusion	NN
cord-342419-liaihahj	369	69	protein	protein	NN
cord-342419-liaihahj	369	70	Characterization	characterization	NN
cord-342419-liaihahj	369	71	of	of	IN
cord-342419-liaihahj	369	72	the	the	DT
cord-342419-liaihahj	369	73	epitope	epitope	NN
cord-342419-liaihahj	369	74	for	for	IN
cord-342419-liaihahj	369	75	anti	anti	JJ
cord-342419-liaihahj	369	76	-	-	JJ
cord-342419-liaihahj	369	77	human	human	JJ
cord-342419-liaihahj	369	78	respiratory	respiratory	JJ
cord-342419-liaihahj	369	79	syncytial	syncytial	JJ
cord-342419-liaihahj	369	80	virus	virus	NN
cord-342419-liaihahj	369	81	F	F	NNP
cord-342419-liaihahj	369	82	protein	protein	NN
cord-342419-liaihahj	369	83	monoclonal	monoclonal	JJ
cord-342419-liaihahj	369	84	antibody	antibody	NN
cord-342419-liaihahj	369	85	101F	101f	CD
cord-342419-liaihahj	369	86	using	use	VBG
cord-342419-liaihahj	369	87	synthetic	synthetic	JJ
cord-342419-liaihahj	369	88	peptides	peptide	NNS
cord-342419-liaihahj	369	89	and	and	CC
cord-342419-liaihahj	369	90	genetic	genetic	JJ
cord-342419-liaihahj	369	91	approaches	approach	NNS
cord-342419-liaihahj	369	92	Anti	anti	JJ
cord-342419-liaihahj	369	93	-	-	JJ
cord-342419-liaihahj	369	94	influenza	influenza	JJ
cord-342419-liaihahj	369	95	H7	H7	NNP
cord-342419-liaihahj	369	96	human	human	JJ
cord-342419-liaihahj	369	97	antibody	antibody	NN
cord-342419-liaihahj	369	98	targets	target	VBZ
cord-342419-liaihahj	369	99	antigenic	antigenic	JJ
cord-342419-liaihahj	369	100	site	site	NN
cord-342419-liaihahj	369	101	in	in	IN
cord-342419-liaihahj	369	102	hemagglutinin	hemagglutinin	NN
cord-342419-liaihahj	369	103	head	head	NN
cord-342419-liaihahj	369	104	domain	domain	NN
cord-342419-liaihahj	369	105	interface	interface	NN
cord-342419-liaihahj	370	1	Influenza	Influenza	NNP
cord-342419-liaihahj	370	2	Antigen	Antigen	NNP
cord-342419-liaihahj	370	3	Engineering	Engineering	NNP
cord-342419-liaihahj	370	4	Focuses	focus	VBZ
cord-342419-liaihahj	370	5	Immune	Immune	NNP
cord-342419-liaihahj	370	6	Responses	response	NNS
cord-342419-liaihahj	370	7	to	to	IN
cord-342419-liaihahj	370	8	a	a	DT
cord-342419-liaihahj	370	9	Subdominant	Subdominant	NNP
cord-342419-liaihahj	370	10	but	but	CC
cord-342419-liaihahj	370	11	Broadly	broadly	RB
cord-342419-liaihahj	370	12	Protective	protective	JJ
cord-342419-liaihahj	370	13	Viral	Viral	NNP
cord-342419-liaihahj	370	14	Epitope	Epitope	NNP
cord-342419-liaihahj	370	15	Antibodies	Antibodies	NNPS
cord-342419-liaihahj	370	16	to	to	IN
cord-342419-liaihahj	370	17	a	a	DT
cord-342419-liaihahj	370	18	Conserved	conserve	VBN
cord-342419-liaihahj	370	19	Influenza	Influenza	NNP
cord-342419-liaihahj	370	20	Head	Head	NNP
cord-342419-liaihahj	370	21	Interface	Interface	NNP
cord-342419-liaihahj	370	22	Epitope	Epitope	NNP
cord-342419-liaihahj	370	23	Protect	Protect	NNP
cord-342419-liaihahj	370	24	by	by	IN
cord-342419-liaihahj	370	25	an	an	DT
cord-342419-liaihahj	370	26	IgG	igg	NN
cord-342419-liaihahj	370	27	Subtype	Subtype	NNP
cord-342419-liaihahj	370	28	-	-	HYPH
cord-342419-liaihahj	370	29	Dependent	Dependent	NNP
cord-342419-liaihahj	370	30	Mechanism	Mechanism	NNP
cord-342419-liaihahj	370	31	Molecular	molecular	JJ
cord-342419-liaihahj	370	32	-	-	HYPH
cord-342419-liaihahj	370	33	level	level	NN
cord-342419-liaihahj	370	34	analysis	analysis	NN
cord-342419-liaihahj	370	35	of	of	IN
cord-342419-liaihahj	370	36	the	the	DT
cord-342419-liaihahj	370	37	serum	serum	NN
cord-342419-liaihahj	370	38	antibody	antibody	NN
cord-342419-liaihahj	370	39	repertoire	repertoire	NN
cord-342419-liaihahj	370	40	in	in	IN
cord-342419-liaihahj	370	41	young	young	JJ
cord-342419-liaihahj	370	42	adults	adult	NNS
cord-342419-liaihahj	370	43	before	before	IN
cord-342419-liaihahj	370	44	and	and	CC
cord-342419-liaihahj	370	45	after	after	IN
cord-342419-liaihahj	370	46	seasonal	seasonal	JJ
cord-342419-liaihahj	370	47	influenza	influenza	NN
cord-342419-liaihahj	370	48	vaccination	vaccination	NN
cord-342419-liaihahj	370	49	A	a	DT
cord-342419-liaihahj	370	50	Site	site	NN
cord-342419-liaihahj	370	51	of	of	IN
cord-342419-liaihahj	370	52	Vulnerability	vulnerability	NN
cord-342419-liaihahj	370	53	on	on	IN
cord-342419-liaihahj	370	54	the	the	DT
cord-342419-liaihahj	370	55	Influenza	Influenza	NNP
cord-342419-liaihahj	370	56	Virus	Virus	NNP
cord-342419-liaihahj	370	57	Hemagglutinin	Hemagglutinin	NNP
cord-342419-liaihahj	370	58	Head	Head	NNP
cord-342419-liaihahj	370	59	Domain	Domain	NNP
cord-342419-liaihahj	371	1	Trimer	Trimer	NNP
cord-342419-liaihahj	371	2	Interface	Interface	NNP
cord-342419-liaihahj	371	3	Transient	Transient	NNP
cord-342419-liaihahj	371	4	opening	opening	NN
cord-342419-liaihahj	371	5	of	of	IN
cord-342419-liaihahj	371	6	trimeric	trimeric	JJ
cord-342419-liaihahj	371	7	prefusion	prefusion	NN
cord-342419-liaihahj	371	8	RSV	RSV	NNP
cord-342419-liaihahj	371	9	F	F	NNP
cord-342419-liaihahj	371	10	proteins	protein	VBZ
cord-342419-liaihahj	371	11	Structure	Structure	NNP
cord-342419-liaihahj	371	12	of	of	IN
cord-342419-liaihahj	371	13	RSV	RSV	NNP
cord-342419-liaihahj	371	14	fusion	fusion	NN
cord-342419-liaihahj	371	15	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	371	16	trimer	trimer	NN
cord-342419-liaihahj	371	17	bound	bind	VBN
cord-342419-liaihahj	371	18	to	to	IN
cord-342419-liaihahj	371	19	a	a	DT
cord-342419-liaihahj	371	20	prefusion	prefusion	NN
cord-342419-liaihahj	371	21	-	-	HYPH
cord-342419-liaihahj	371	22	specific	specific	JJ
cord-342419-liaihahj	371	23	neutralizing	neutralize	VBG
cord-342419-liaihahj	371	24	antibody	antibody	NN
cord-342419-liaihahj	371	25	Conformational	Conformational	NNP
cord-342419-liaihahj	371	26	dynamics	dynamic	NNS
cord-342419-liaihahj	371	27	of	of	IN
cord-342419-liaihahj	371	28	single	single	JJ
cord-342419-liaihahj	371	29	HIV-1	HIV-1	NNP
cord-342419-liaihahj	371	30	envelope	envelope	NN
cord-342419-liaihahj	371	31	trimers	trimer	NNS
cord-342419-liaihahj	371	32	on	on	IN
cord-342419-liaihahj	371	33	the	the	DT
cord-342419-liaihahj	371	34	surface	surface	NN
cord-342419-liaihahj	371	35	of	of	IN
cord-342419-liaihahj	371	36	native	native	JJ
cord-342419-liaihahj	371	37	virions	virion	NNS
cord-342419-liaihahj	371	38	Intermediate	intermediate	JJ
cord-342419-liaihahj	371	39	conformations	conformation	NNS
cord-342419-liaihahj	371	40	during	during	IN
cord-342419-liaihahj	371	41	viral	viral	JJ
cord-342419-liaihahj	371	42	fusion	fusion	NN
cord-342419-liaihahj	371	43	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	371	44	structural	structural	JJ
cord-342419-liaihahj	371	45	transition	transition	NN
cord-342419-liaihahj	371	46	Antibodies	Antibodies	NNP
cord-342419-liaihahj	371	47	to	to	IN
cord-342419-liaihahj	371	48	a	a	DT
cord-342419-liaihahj	371	49	conformational	conformational	JJ
cord-342419-liaihahj	371	50	epitope	epitope	NN
cord-342419-liaihahj	371	51	on	on	IN
cord-342419-liaihahj	371	52	gp41	gp41	NNP
cord-342419-liaihahj	371	53	neutralize	neutralize	VB
cord-342419-liaihahj	371	54	HIV-1	HIV-1	NNP
cord-342419-liaihahj	371	55	by	by	IN
cord-342419-liaihahj	371	56	destabilizing	destabilize	VBG
cord-342419-liaihahj	371	57	the	the	DT
cord-342419-liaihahj	371	58	Env	Env	NNP
cord-342419-liaihahj	371	59	spike	spike	NN
cord-342419-liaihahj	371	60	Structure	Structure	NNP
cord-342419-liaihahj	371	61	of	of	IN
cord-342419-liaihahj	371	62	a	a	DT
cord-342419-liaihahj	371	63	major	major	JJ
cord-342419-liaihahj	371	64	antigenic	antigenic	JJ
cord-342419-liaihahj	371	65	site	site	NN
cord-342419-liaihahj	371	66	on	on	IN
cord-342419-liaihahj	371	67	the	the	DT
cord-342419-liaihahj	371	68	respiratory	respiratory	JJ
cord-342419-liaihahj	371	69	syncytial	syncytial	JJ
cord-342419-liaihahj	371	70	virus	virus	NN
cord-342419-liaihahj	371	71	fusion	fusion	NN
cord-342419-liaihahj	371	72	glycoprotein	glycoprotein	NN
cord-342419-liaihahj	371	73	in	in	IN
cord-342419-liaihahj	371	74	complex	complex	NN
cord-342419-liaihahj	371	75	with	with	IN
cord-342419-liaihahj	371	76	neutralizing	neutralize	VBG
cord-342419-liaihahj	371	77	antibody	antibody	NN
cord-342419-liaihahj	371	78	101F	101f	CD
cord-342419-liaihahj	371	79	Efficient	efficient	JJ
cord-342419-liaihahj	371	80	generation	generation	NN
cord-342419-liaihahj	371	81	of	of	IN
cord-342419-liaihahj	371	82	monoclonal	monoclonal	JJ
cord-342419-liaihahj	371	83	antibodies	antibody	NNS
cord-342419-liaihahj	371	84	from	from	IN
cord-342419-liaihahj	371	85	single	single	JJ
cord-342419-liaihahj	371	86	human	human	NN
cord-342419-liaihahj	371	87	B	b	NN
cord-342419-liaihahj	371	88	cells	cell	NNS
cord-342419-liaihahj	371	89	by	by	IN
cord-342419-liaihahj	371	90	single	single	JJ
cord-342419-liaihahj	371	91	cell	cell	NN
cord-342419-liaihahj	371	92	RT	rt	NN
cord-342419-liaihahj	371	93	-	-	HYPH
cord-342419-liaihahj	371	94	PCR	PCR	NNP
cord-342419-liaihahj	371	95	and	and	CC
cord-342419-liaihahj	371	96	expression	expression	NN
cord-342419-liaihahj	371	97	vector	vector	NN
cord-342419-liaihahj	372	1	cloning	clone	VBG
cord-342419-liaihahj	372	2	IMGT	IMGT	NNP
cord-342419-liaihahj	372	3	/	/	SYM
cord-342419-liaihahj	372	4	V	v	NN
cord-342419-liaihahj	372	5	-	-	HYPH
cord-342419-liaihahj	372	6	QUEST	quest	NN
cord-342419-liaihahj	372	7	:	:	:
cord-342419-liaihahj	373	1	the	the	DT
cord-342419-liaihahj	373	2	highly	highly	RB
cord-342419-liaihahj	373	3	customized	customize	VBN
cord-342419-liaihahj	373	4	and	and	CC
cord-342419-liaihahj	373	5	integrated	integrated	JJ
cord-342419-liaihahj	373	6	system	system	NN
cord-342419-liaihahj	373	7	for	for	IN
cord-342419-liaihahj	373	8	IG	IG	NNP
cord-342419-liaihahj	373	9	and	and	CC
cord-342419-liaihahj	373	10	TR	TR	NNP
cord-342419-liaihahj	373	11	standardized	standardized	JJ
cord-342419-liaihahj	373	12	V	V	NNP
cord-342419-liaihahj	373	13	-	-	HYPH
cord-342419-liaihahj	373	14	J	J	NNP
cord-342419-liaihahj	373	15	and	and	CC
cord-342419-liaihahj	373	16	V	v	NN
cord-342419-liaihahj	373	17	-	-	HYPH
cord-342419-liaihahj	373	18	D	D	NNP
cord-342419-liaihahj	373	19	-	-	HYPH
cord-342419-liaihahj	373	20	J	J	NNP
cord-342419-liaihahj	373	21	sequence	sequence	NN
cord-342419-liaihahj	373	22	analysis	analysis	NN
cord-342419-liaihahj	373	23	PHENIX	PHENIX	NNP
cord-342419-liaihahj	373	24	:	:	:
cord-342419-liaihahj	373	25	a	a	DT
cord-342419-liaihahj	373	26	comprehensive	comprehensive	JJ
cord-342419-liaihahj	373	27	Python	Python	NNP
cord-342419-liaihahj	373	28	-	-	HYPH
cord-342419-liaihahj	373	29	based	base	VBN
cord-342419-liaihahj	373	30	system	system	NN
cord-342419-liaihahj	373	31	for	for	IN
cord-342419-liaihahj	373	32	macromolecular	macromolecular	JJ
cord-342419-liaihahj	373	33	structure	structure	NN
cord-342419-liaihahj	373	34	solution	solution	NN
cord-342419-liaihahj	373	35	Coot	Coot	NNP
cord-342419-liaihahj	373	36	:	:	:
cord-342419-liaihahj	373	37	model	model	NN
cord-342419-liaihahj	373	38	-	-	HYPH
cord-342419-liaihahj	373	39	building	building	NN
cord-342419-liaihahj	373	40	tools	tool	NNS
cord-342419-liaihahj	373	41	for	for	IN
cord-342419-liaihahj	373	42	molecular	molecular	JJ
cord-342419-liaihahj	373	43	graphics	graphic	NNS
cord-342419-liaihahj	373	44	X	x	NN
cord-342419-liaihahj	373	45	-	-	NN
cord-342419-liaihahj	373	46	ray	ray	NN
cord-342419-liaihahj	373	47	data	datum	NNS
cord-342419-liaihahj	373	48	were	be	VBD
cord-342419-liaihahj	373	49	collected	collect	VBN
cord-342419-liaihahj	373	50	at	at	IN
cord-342419-liaihahj	373	51	the	the	DT
cord-342419-liaihahj	373	52	Southeast	Southeast	NNP
cord-342419-liaihahj	373	53	Regional	Regional	NNP
cord-342419-liaihahj	373	54	Collaborative	Collaborative	NNP
cord-342419-liaihahj	373	55	Access	Access	NNP
cord-342419-liaihahj	373	56	Team	Team	NNP
cord-342419-liaihahj	373	57	(	(	-LRB-
cord-342419-liaihahj	373	58	SER	SER	NNP
cord-342419-liaihahj	373	59	-	-	HYPH
cord-342419-liaihahj	373	60	CAT	CAT	NNP
cord-342419-liaihahj	373	61	)	)	-RRB-
cord-342419-liaihahj	373	62	22	22	CD
cord-342419-liaihahj	373	63	-ID	-id	NN
cord-342419-liaihahj	373	64	beamline	beamline	NN
cord-342419-liaihahj	373	65	at	at	IN
cord-342419-liaihahj	373	66	the	the	DT
cord-342419-liaihahj	373	67	Advanced	Advanced	NNP
cord-342419-liaihahj	373	68	Photon	Photon	NNP
cord-342419-liaihahj	373	69	Source	Source	NNP
cord-342419-liaihahj	373	70	,	,	,
cord-342419-liaihahj	373	71	Argonne	Argonne	NNP
cord-342419-liaihahj	373	72	National	National	NNP
cord-342419-liaihahj	373	73	Laboratory	Laboratory	NNP
cord-342419-liaihahj	373	74	.	.	.
cord-342419-liaihahj	374	1	SER	SER	NNP
cord-342419-liaihahj	374	2	-	-	HYPH
cord-342419-liaihahj	374	3	CAT	CAT	NNP
cord-342419-liaihahj	374	4	is	be	VBZ
cord-342419-liaihahj	374	5	supported	support	VBN
cord-342419-liaihahj	374	6	by	by	IN
cord-342419-liaihahj	374	7	its	-PRON-	PRP$
cord-342419-liaihahj	374	8	member	member	NN
cord-342419-liaihahj	374	9	institutions	institution	NNS
cord-342419-liaihahj	374	10	(	(	-LRB-
cord-342419-liaihahj	374	11	see	see	VB
cord-342419-liaihahj	374	12	www.ser-cat.org/members.html	www.ser-cat.org/members.html	NNP
cord-342419-liaihahj	374	13	)	)	-RRB-
cord-342419-liaihahj	374	14	,	,	,
cord-342419-liaihahj	374	15	and	and	CC
cord-342419-liaihahj	374	16	equipment	equipment	NN
cord-342419-liaihahj	374	17	grants	grant	NNS
cord-342419-liaihahj	374	18	(	(	-LRB-
cord-342419-liaihahj	374	19	S10_RR25528	S10_RR25528	NNP
cord-342419-liaihahj	374	20	and	and	CC
cord-342419-liaihahj	374	21	S10_RR028976	S10_RR028976	NNP
cord-342419-liaihahj	374	22	)	)	-RRB-
cord-342419-liaihahj	374	23	from	from	IN
cord-342419-liaihahj	374	24	the	the	DT
cord-342419-liaihahj	374	25	National	National	NNP
cord-342419-liaihahj	374	26	Institutes	Institutes	NNPS
cord-342419-liaihahj	374	27	of	of	IN
cord-342419-liaihahj	374	28	Health	Health	NNP
cord-342419-liaihahj	374	29	.	.	.
cord-342419-liaihahj	375	1	Use	use	NN
cord-342419-liaihahj	375	2	of	of	IN
cord-342419-liaihahj	375	3	the	the	DT
cord-342419-liaihahj	375	4	Advanced	Advanced	NNP
cord-342419-liaihahj	375	5	Photon	Photon	NNP
cord-342419-liaihahj	375	6	Source	Source	NNP
cord-342419-liaihahj	375	7	was	be	VBD
cord-342419-liaihahj	375	8	supported	support	VBN
cord-342419-liaihahj	375	9	by	by	IN
cord-342419-liaihahj	375	10	the	the	DT
cord-342419-liaihahj	375	11	U.S.	U.S.	NNP
cord-342419-liaihahj	375	12	Department	Department	NNP
cord-342419-liaihahj	375	13	of	of	IN
cord-342419-liaihahj	375	14	Energy	Energy	NNP
cord-342419-liaihahj	375	15	,	,	,
cord-342419-liaihahj	375	16	Office	Office	NNP
cord-342419-liaihahj	375	17	of	of	IN
cord-342419-liaihahj	375	18	Science	Science	NNP
cord-342419-liaihahj	375	19	,	,	,
cord-342419-liaihahj	375	20	Office	Office	NNP
cord-342419-liaihahj	375	21	of	of	IN
cord-342419-liaihahj	375	22	Basic	Basic	NNP
cord-342419-liaihahj	375	23	Energy	Energy	NNP
cord-342419-liaihahj	375	24	Sciences	Sciences	NNPS
cord-342419-liaihahj	375	25	,	,	,
cord-342419-liaihahj	375	26	under	under	IN
cord-342419-liaihahj	375	27	Contract	Contract	NNP
cord-342419-liaihahj	375	28	No	no	NN
cord-342419-liaihahj	375	29	.	.	.
cord-342419-liaihahj	375	30	W-31	W-31	NNP
cord-342419-liaihahj	375	31	-	-	HYPH
cord-342419-liaihahj	375	32	109-Eng-38.We	109-eng-38.we	CD
cord-342419-liaihahj	375	33	thank	thank	VBP
cord-342419-liaihahj	375	34	Georgia	Georgia	NNP
cord-342419-liaihahj	375	35	Electron	Electron	NNP
cord-342419-liaihahj	375	36	Microscopy	Microscopy	NNP
cord-342419-liaihahj	375	37	at	at	IN
cord-342419-liaihahj	375	38	the	the	DT
cord-342419-liaihahj	375	39	University	University	NNP
cord-342419-liaihahj	375	40	of	of	IN
cord-342419-liaihahj	375	41	Georgia	Georgia	NNP
cord-342419-liaihahj	375	42	for	for	IN
cord-342419-liaihahj	375	43	assistance	assistance	NN
cord-342419-liaihahj	375	44	with	with	IN
cord-342419-liaihahj	375	45	negative	negative	JJ
cord-342419-liaihahj	375	46	-	-	HYPH
cord-342419-liaihahj	375	47	stain	stain	NN
cord-342419-liaihahj	375	48	electron	electron	NN
cord-342419-liaihahj	375	49	microscopy	microscopy	NN
cord-342419-liaihahj	375	50	,	,	,
cord-342419-liaihahj	375	51	the	the	DT
cord-342419-liaihahj	375	52	University	University	NNP
cord-342419-liaihahj	375	53	of	of	IN
cord-342419-liaihahj	375	54	Georgia	Georgia	NNP
cord-342419-liaihahj	375	55	Clinical	Clinical	NNP
cord-342419-liaihahj	375	56	and	and	CC
cord-342419-liaihahj	375	57	Translational	Translational	NNP
cord-342419-liaihahj	375	58	Research	Research	NNP
cord-342419-liaihahj	375	59	Unit	Unit	NNP
cord-342419-liaihahj	375	60	for	for	IN
cord-342419-liaihahj	375	61	assistance	assistance	NN
cord-342419-liaihahj	375	62	with	with	IN
cord-342419-liaihahj	375	63	donor	donor	NN
cord-342419-liaihahj	375	64	identification	identification	NN
cord-342419-liaihahj	375	65	and	and	CC
cord-342419-liaihahj	375	66	blood	blood	NN
cord-342419-liaihahj	375	67	draws	draw	VBZ
cord-342419-liaihahj	375	68	,	,	,
cord-342419-liaihahj	375	69	and	and	CC
cord-342419-liaihahj	375	70	the	the	DT
cord-342419-liaihahj	375	71	University	University	NNP
cord-342419-liaihahj	375	72	of	of	IN
cord-342419-liaihahj	375	73	Georgia	Georgia	NNP
cord-342419-liaihahj	375	74	Center	Center	NNP
cord-342419-liaihahj	375	75	for	for	IN
cord-342419-liaihahj	375	76	Tropical	Tropical	NNP
cord-342419-liaihahj	375	77	and	and	CC
cord-342419-liaihahj	375	78	Emerging	Emerging	NNP
cord-342419-liaihahj	375	79	Global	Global	NNP
cord-342419-liaihahj	375	80	Diseases	Diseases	NNPS
cord-342419-liaihahj	375	81	flow	flow	NN
cord-342419-liaihahj	375	82	cytometry	cytometry	NN
cord-342419-liaihahj	375	83	core	core	NN
cord-342419-liaihahj	375	84	for	for	IN
cord-342419-liaihahj	375	85	assistance	assistance	NN
cord-342419-liaihahj	375	86	with	with	IN
cord-342419-liaihahj	375	87	cell	cell	NN
cord-342419-liaihahj	375	88	sorting	sorting	NN
cord-342419-liaihahj	375	89	.	.	.
cord-342419-liaihahj	376	1	The	the	DT
cord-342419-liaihahj	376	2	content	content	NN
cord-342419-liaihahj	376	3	is	be	VBZ
cord-342419-liaihahj	376	4	solely	solely	RB
cord-342419-liaihahj	376	5	the	the	DT
cord-342419-liaihahj	376	6	responsibility	responsibility	NN
cord-342419-liaihahj	376	7	of	of	IN
cord-342419-liaihahj	376	8	the	the	DT
cord-342419-liaihahj	376	9	authors	author	NNS
cord-342419-liaihahj	376	10	and	and	CC
cord-342419-liaihahj	376	11	does	do	VBZ
cord-342419-liaihahj	376	12	not	not	RB
cord-342419-liaihahj	376	13	necessarily	necessarily	RB
cord-342419-liaihahj	376	14	represent	represent	VB
cord-342419-liaihahj	376	15	the	the	DT
cord-342419-liaihahj	376	16	official	official	JJ
cord-342419-liaihahj	376	17	views	view	NNS
cord-342419-liaihahj	376	18	of	of	IN
cord-342419-liaihahj	376	19	the	the	DT
cord-342419-liaihahj	376	20	National	National	NNP
cord-342419-liaihahj	376	21	Institutes	Institutes	NNPS
cord-342419-liaihahj	376	22	of	of	IN
cord-342419-liaihahj	376	23	Health	Health	NNP
cord-342419-liaihahj	376	24	.	.	.
cord-342419-liaihahj	377	1	The	the	DT
cord-342419-liaihahj	377	2	structure	structure	NN
cord-342419-liaihahj	377	3	factors	factor	NNS
cord-342419-liaihahj	377	4	and	and	CC
cord-342419-liaihahj	377	5	structure	structure	NN
cord-342419-liaihahj	377	6	coordinates	coordinate	NNS
cord-342419-liaihahj	377	7	were	be	VBD
cord-342419-liaihahj	377	8	deposited	deposit	VBN
cord-342419-liaihahj	377	9	to	to	IN
cord-342419-liaihahj	377	10	the	the	DT
cord-342419-liaihahj	377	11	Protein	Protein	NNP
cord-342419-liaihahj	377	12	Data	Data	NNP
cord-342419-liaihahj	377	13	Bank	Bank	NNP
cord-342419-liaihahj	377	14	under	under	IN
cord-342419-liaihahj	377	15	accession	accession	NNP
cord-342419-liaihahj	377	16	code	code	NNP
cord-342419-liaihahj	377	17	6W16	6w16	CD
cord-342419-liaihahj	377	18	.	.	.
cord-342419-liaihahj	378	1	Conceptualization	conceptualization	NN
cord-342419-liaihahj	378	2	:	:	:
cord-342419-liaihahj	378	3	Jarrod	Jarrod	NNP
cord-342419-liaihahj	378	4	J.	J.	NNP
cord-342419-liaihahj	378	5	Mousa	Mousa	NNP
cord-342419-liaihahj	378	6	.	.	.
cord-342419-liaihahj	378	7	 	 	_SP