id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-284785-mkjogy6h	Trevisan, Caterina	Labile PT-INR in a Covid-19 Patient Under Long-term Vitamin K Antagonist Therapy: a Case Report	2020-08-19		.txt	text/plain	1314	68	50	The patient's medical history included moderate cognitive impairment, atrial fibrillation under oral anticoagulation (warfarin 2.5 mg and 3.75 mg on alternate days, showing stable PT-INR values since October 2018), and arterial hypertension. On April 20, blood analyses revealed hemoglobin 117 g/l, PT-INR 2.15, and a slight alteration of liver function with AST 55 U/l (normal range: 5-32). The temporal relationship between COVID-19 onset and PT-INR elevation in a patient whose PT-INR values were stable in the 18 months before the hospitalization supports the hypothesis that this infection may impact on the coagulative pattern not only pro-thrombotically [4, 5] but also by increasing hemorrhagic risk. This confirms that special attention should be paid to COVID-19 patients under long-term anticoagulation with vitamin K antagonist and a shift to heparin treatment until illness resolution may be a safe option in these individuals [7] .	./cache/cord-284785-mkjogy6h.txt	./txt/cord-284785-mkjogy6h.txt