id author title date pages extension mime words sentences flesch summary cache txt cord-285748-us5do6c2 Cheng, Yongqian SARS-CoV-2-Related Kidney Injury: Current Concern and Challenges 2020-09-23 .txt text/plain 5322 295 48 Currently, the diagnosis and treatment of SARS-CoV-2 infection in patients with chronic kidney disease (CKD) are still unclear. Here, we review the recent findings of characteristics of COVID-19 in CKD patients and highlight the possible mechanisms of kidney injury caused by SARS-CoV-2 infection. Controversial results also exist like another study [18] indicating that SARS-CoV-2 infection was not found significantly correlated with incremental acute renal injury or aggravate chronic kidney failure in the COVID-19 patients. Therefore, SARS-CoV-2 infection in kidney transplant patients from this study showed that such cases may be severe enough requiring intensive care admission and these patients are in high risk of disease progression and death. Another study based on single-cell analysis by Lin and colleagues [28] also found that ACE2 was enriched in proximal tubular cells which may indicate that the kidney is more susceptible to SARS-CoV-2 infection. ./cache/cord-285748-us5do6c2.txt ./txt/cord-285748-us5do6c2.txt