id author title date pages extension mime words sentences flesch summary cache txt cord-308298-5ntdb8yf Mair, Kerstin H Porcine CD8α(dim/-)NKp46(high) NK cells are in a highly activated state 2013-03-01 .txt text/plain 7630 429 56 Functional analyses revealed that splenic NKp46(high) NK cells produced much higher levels of Interferon-γ and Tumor Necrosis Factor-α upon stimulation with cytokines or phorbol-12-myristate-13-acetate/Ionomycin compared to the other two subsets. Splenic NKp46 high NK cells showed a significantly reduced level of CD8α expression compared to the other splenic NK-cell subsets in all animals analysed Sequences of primers (5'-3') for target genes as well as primer positions on (+) strand, length of specific product in base pairs (bp) and product melting temperature in°C are indicated. Splenic NKp46 high NK cells showed an overall higher expression of this receptor compared to NKp46and NKp46 + NK-cell subsets from both spleen and blood. Splenic NKp46 high NK cells showed highly elevated expression of this activating receptor compared to the other two NKp46-defined subsets in spleen as well as in blood in all animals analysed, which could be demonstrated on protein as well as on mRNA level. ./cache/cord-308298-5ntdb8yf.txt ./txt/cord-308298-5ntdb8yf.txt