id	sid	tid	token	lemma	pos
cord-322166-ajolu2rh	1	1	key	key	JJ
cord-322166-ajolu2rh	1	2	:	:	:
cord-322166-ajolu2rh	1	3	cord-322166-ajolu2rh	cord-322166-ajolu2rh	DT
cord-322166-ajolu2rh	1	4	authors	author	NNS
cord-322166-ajolu2rh	1	5	:	:	:
cord-322166-ajolu2rh	1	6	Yin	Yin	NNP
cord-322166-ajolu2rh	1	7	,	,	,
cord-322166-ajolu2rh	1	8	Jingchuan	Jingchuan	NNP
cord-322166-ajolu2rh	1	9	;	;	:
cord-322166-ajolu2rh	1	10	Liu	Liu	NNP
cord-322166-ajolu2rh	1	11	,	,	,
cord-322166-ajolu2rh	1	12	Shi	Shi	NNP
cord-322166-ajolu2rh	1	13	;	;	:
cord-322166-ajolu2rh	1	14	Zhu	Zhu	NNP
cord-322166-ajolu2rh	1	15	,	,	,
cord-322166-ajolu2rh	1	16	Ying	Ying	NNP
cord-322166-ajolu2rh	1	17	title	title	NN
cord-322166-ajolu2rh	1	18	:	:	:
cord-322166-ajolu2rh	2	1	An	an	DT
cord-322166-ajolu2rh	2	2	overview	overview	NN
cord-322166-ajolu2rh	2	3	of	of	IN
cord-322166-ajolu2rh	2	4	the	the	DT
cord-322166-ajolu2rh	2	5	highly	highly	RB
cord-322166-ajolu2rh	2	6	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	2	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	2	8	influenza	influenza	NN
cord-322166-ajolu2rh	2	9	virus	virus	NN
cord-322166-ajolu2rh	2	10	date	date	NN
cord-322166-ajolu2rh	2	11	:	:	:
cord-322166-ajolu2rh	2	12	2013	2013	CD
cord-322166-ajolu2rh	2	13	-	-	SYM
cord-322166-ajolu2rh	2	14	01	01	CD
cord-322166-ajolu2rh	2	15	-	-	HYPH
cord-322166-ajolu2rh	2	16	16	16	CD
cord-322166-ajolu2rh	2	17	journal	journal	NN
cord-322166-ajolu2rh	2	18	:	:	:
cord-322166-ajolu2rh	3	1	Virol	Virol	NNP
cord-322166-ajolu2rh	4	1	Sin	sin	NN
cord-322166-ajolu2rh	4	2	DOI	DOI	NNP
cord-322166-ajolu2rh	4	3	:	:	:
cord-322166-ajolu2rh	4	4	10.1007	10.1007	CD
cord-322166-ajolu2rh	4	5	/	/	SYM
cord-322166-ajolu2rh	4	6	s12250	s12250	JJ
cord-322166-ajolu2rh	4	7	-	-	HYPH
cord-322166-ajolu2rh	4	8	013	013	CD
cord-322166-ajolu2rh	4	9	-	-	HYPH
cord-322166-ajolu2rh	4	10	3294	3294	CD
cord-322166-ajolu2rh	4	11	-	-	HYPH
cord-322166-ajolu2rh	4	12	9	9	CD
cord-322166-ajolu2rh	4	13	sha	sha	NN
cord-322166-ajolu2rh	4	14	:	:	:
cord-322166-ajolu2rh	5	1	9bda60a5736d4582448f8f600a2fe609b02b7419	9bda60a5736d4582448f8f600a2fe609b02b7419	CD
cord-322166-ajolu2rh	5	2	doc_id	doc_id	CD
cord-322166-ajolu2rh	5	3	:	:	:
cord-322166-ajolu2rh	5	4	322166	322166	CD
cord-322166-ajolu2rh	5	5	cord_uid	cord_uid	NN
cord-322166-ajolu2rh	5	6	:	:	:
cord-322166-ajolu2rh	6	1	ajolu2rh	ajolu2rh	RB
cord-322166-ajolu2rh	6	2	Since	since	IN
cord-322166-ajolu2rh	6	3	the	the	DT
cord-322166-ajolu2rh	6	4	first	first	JJ
cord-322166-ajolu2rh	6	5	human	human	JJ
cord-322166-ajolu2rh	6	6	case	case	NN
cord-322166-ajolu2rh	6	7	of	of	IN
cord-322166-ajolu2rh	6	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	6	9	avian	avian	JJ
cord-322166-ajolu2rh	6	10	influenza	influenza	NN
cord-322166-ajolu2rh	6	11	virus	virus	NN
cord-322166-ajolu2rh	6	12	infection	infection	NN
cord-322166-ajolu2rh	6	13	was	be	VBD
cord-322166-ajolu2rh	6	14	reported	report	VBN
cord-322166-ajolu2rh	6	15	in	in	IN
cord-322166-ajolu2rh	6	16	1997	1997	CD
cord-322166-ajolu2rh	6	17	,	,	,
cord-322166-ajolu2rh	6	18	this	this	DT
cord-322166-ajolu2rh	6	19	highly	highly	RB
cord-322166-ajolu2rh	6	20	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	6	21	virus	virus	NN
cord-322166-ajolu2rh	6	22	has	have	VBZ
cord-322166-ajolu2rh	6	23	infected	infect	VBN
cord-322166-ajolu2rh	6	24	hundreds	hundred	NNS
cord-322166-ajolu2rh	6	25	of	of	IN
cord-322166-ajolu2rh	6	26	people	people	NNS
cord-322166-ajolu2rh	6	27	around	around	IN
cord-322166-ajolu2rh	6	28	the	the	DT
cord-322166-ajolu2rh	6	29	world	world	NN
cord-322166-ajolu2rh	6	30	and	and	CC
cord-322166-ajolu2rh	6	31	resulted	result	VBD
cord-322166-ajolu2rh	6	32	in	in	IN
cord-322166-ajolu2rh	6	33	many	many	JJ
cord-322166-ajolu2rh	6	34	deaths	death	NNS
cord-322166-ajolu2rh	6	35	.	.	.
cord-322166-ajolu2rh	7	1	The	the	DT
cord-322166-ajolu2rh	7	2	ability	ability	NN
cord-322166-ajolu2rh	7	3	of	of	IN
cord-322166-ajolu2rh	7	4	H5N1	H5N1	NNP
cord-322166-ajolu2rh	7	5	to	to	TO
cord-322166-ajolu2rh	7	6	cross	cross	VB
cord-322166-ajolu2rh	7	7	species	species	NN
cord-322166-ajolu2rh	7	8	boundaries	boundary	NNS
cord-322166-ajolu2rh	7	9	,	,	,
cord-322166-ajolu2rh	7	10	and	and	CC
cord-322166-ajolu2rh	7	11	the	the	DT
cord-322166-ajolu2rh	7	12	presence	presence	NN
cord-322166-ajolu2rh	7	13	of	of	IN
cord-322166-ajolu2rh	7	14	polymorphisms	polymorphism	NNS
cord-322166-ajolu2rh	7	15	that	that	WDT
cord-322166-ajolu2rh	7	16	enhance	enhance	VBP
cord-322166-ajolu2rh	7	17	virulence	virulence	NN
cord-322166-ajolu2rh	7	18	,	,	,
cord-322166-ajolu2rh	7	19	present	present	JJ
cord-322166-ajolu2rh	7	20	challenges	challenge	NNS
cord-322166-ajolu2rh	7	21	to	to	IN
cord-322166-ajolu2rh	7	22	developing	develop	VBG
cord-322166-ajolu2rh	7	23	clear	clear	JJ
cord-322166-ajolu2rh	7	24	strategies	strategy	NNS
cord-322166-ajolu2rh	7	25	to	to	TO
cord-322166-ajolu2rh	7	26	prevent	prevent	VB
cord-322166-ajolu2rh	7	27	the	the	DT
cord-322166-ajolu2rh	7	28	pandemic	pandemic	NN
cord-322166-ajolu2rh	7	29	spread	spread	NN
cord-322166-ajolu2rh	7	30	of	of	IN
cord-322166-ajolu2rh	7	31	this	this	DT
cord-322166-ajolu2rh	7	32	highly	highly	RB
cord-322166-ajolu2rh	7	33	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	7	34	avian	avian	JJ
cord-322166-ajolu2rh	7	35	influenza	influenza	NN
cord-322166-ajolu2rh	7	36	(	(	-LRB-
cord-322166-ajolu2rh	7	37	HPAI	HPAI	NNP
cord-322166-ajolu2rh	7	38	)	)	-RRB-
cord-322166-ajolu2rh	7	39	virus	virus	NN
cord-322166-ajolu2rh	7	40	.	.	.
cord-322166-ajolu2rh	8	1	This	this	DT
cord-322166-ajolu2rh	8	2	review	review	NN
cord-322166-ajolu2rh	8	3	summarizes	summarize	VBZ
cord-322166-ajolu2rh	8	4	the	the	DT
cord-322166-ajolu2rh	8	5	current	current	JJ
cord-322166-ajolu2rh	8	6	understanding	understanding	NN
cord-322166-ajolu2rh	8	7	of	of	IN
cord-322166-ajolu2rh	8	8	,	,	,
cord-322166-ajolu2rh	8	9	and	and	CC
cord-322166-ajolu2rh	8	10	recent	recent	JJ
cord-322166-ajolu2rh	8	11	research	research	NN
cord-322166-ajolu2rh	8	12	on	on	IN
cord-322166-ajolu2rh	8	13	,	,	,
cord-322166-ajolu2rh	8	14	the	the	DT
cord-322166-ajolu2rh	8	15	avian	avian	JJ
cord-322166-ajolu2rh	8	16	influenza	influenza	NN
cord-322166-ajolu2rh	8	17	H5N1	H5N1	NNP
cord-322166-ajolu2rh	8	18	virus	virus	NN
cord-322166-ajolu2rh	8	19	,	,	,
cord-322166-ajolu2rh	8	20	including	include	VBG
cord-322166-ajolu2rh	8	21	transmission	transmission	NN
cord-322166-ajolu2rh	8	22	,	,	,
cord-322166-ajolu2rh	8	23	virulence	virulence	NN
cord-322166-ajolu2rh	8	24	,	,	,
cord-322166-ajolu2rh	8	25	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	8	26	,	,	,
cord-322166-ajolu2rh	8	27	clinical	clinical	JJ
cord-322166-ajolu2rh	8	28	characteristics	characteristic	NNS
cord-322166-ajolu2rh	8	29	,	,	,
cord-322166-ajolu2rh	8	30	treatment	treatment	NN
cord-322166-ajolu2rh	8	31	and	and	CC
cord-322166-ajolu2rh	8	32	prevention	prevention	NN
cord-322166-ajolu2rh	8	33	.	.	.
cord-322166-ajolu2rh	9	1	Influenza	influenza	NN
cord-322166-ajolu2rh	9	2	virus	virus	NN
cord-322166-ajolu2rh	9	3	belongs	belong	VBZ
cord-322166-ajolu2rh	9	4	to	to	IN
cord-322166-ajolu2rh	9	5	the	the	DT
cord-322166-ajolu2rh	9	6	family	family	NN
cord-322166-ajolu2rh	9	7	Orthomyxoviridae	Orthomyxoviridae	NNP
cord-322166-ajolu2rh	10	1	(	(	-LRB-
cord-322166-ajolu2rh	10	2	Nelson	Nelson	NNP
cord-322166-ajolu2rh	10	3	M	M	NNP
cord-322166-ajolu2rh	10	4	I	I	NNP
cord-322166-ajolu2rh	10	5	,	,	,
cord-322166-ajolu2rh	10	6	et	et	NNP
cord-322166-ajolu2rh	10	7	al	al	NNP
cord-322166-ajolu2rh	10	8	.	.	NNP
cord-322166-ajolu2rh	10	9	,	,	,
cord-322166-ajolu2rh	10	10	2007	2007	CD
cord-322166-ajolu2rh	10	11	)	)	-RRB-
cord-322166-ajolu2rh	10	12	,	,	,
cord-322166-ajolu2rh	10	13	which	which	WDT
cord-322166-ajolu2rh	10	14	contains	contain	VBZ
cord-322166-ajolu2rh	10	15	three	three	CD
cord-322166-ajolu2rh	10	16	different	different	JJ
cord-322166-ajolu2rh	10	17	genera	genus	NNS
cord-322166-ajolu2rh	10	18	of	of	IN
cord-322166-ajolu2rh	10	19	influenza	influenza	NN
cord-322166-ajolu2rh	10	20	virus	virus	NN
cord-322166-ajolu2rh	10	21	:	:	:
cord-322166-ajolu2rh	10	22	type	type	NN
cord-322166-ajolu2rh	10	23	A	a	NN
cord-322166-ajolu2rh	10	24	,	,	,
cord-322166-ajolu2rh	10	25	type	type	NN
cord-322166-ajolu2rh	10	26	B	b	NN
cord-322166-ajolu2rh	10	27	,	,	,
cord-322166-ajolu2rh	10	28	and	and	CC
cord-322166-ajolu2rh	10	29	type	type	NN
cord-322166-ajolu2rh	10	30	C	C	NNP
cord-322166-ajolu2rh	10	31	(	(	-LRB-
cord-322166-ajolu2rh	10	32	Shaw	Shaw	NNP
cord-322166-ajolu2rh	10	33	M	M	NNP
cord-322166-ajolu2rh	10	34	,	,	,
cord-322166-ajolu2rh	10	35	et	et	NNP
cord-322166-ajolu2rh	10	36	al	al	NNP
cord-322166-ajolu2rh	10	37	.	.	NNP
cord-322166-ajolu2rh	10	38	,	,	,
cord-322166-ajolu2rh	10	39	1992	1992	CD
cord-322166-ajolu2rh	10	40	)	)	-RRB-
cord-322166-ajolu2rh	10	41	.	.	.
cord-322166-ajolu2rh	11	1	Influenza	influenza	NN
cord-322166-ajolu2rh	11	2	viruses	virus	NNS
cord-322166-ajolu2rh	11	3	are	be	VBP
cord-322166-ajolu2rh	11	4	enveloped	envelop	VBN
cord-322166-ajolu2rh	11	5	RNA	RNA	NNP
cord-322166-ajolu2rh	11	6	viruses	virus	NNS
cord-322166-ajolu2rh	11	7	with	with	IN
cord-322166-ajolu2rh	11	8	a	a	DT
cord-322166-ajolu2rh	11	9	genome	genome	NN
cord-322166-ajolu2rh	11	10	of	of	IN
cord-322166-ajolu2rh	11	11	seven	seven	CD
cord-322166-ajolu2rh	11	12	or	or	CC
cord-322166-ajolu2rh	11	13	eight	eight	CD
cord-322166-ajolu2rh	11	14	single	single	JJ
cord-322166-ajolu2rh	11	15	-	-	HYPH
cord-322166-ajolu2rh	11	16	stranded	strand	VBN
cord-322166-ajolu2rh	11	17	negative	negative	JJ
cord-322166-ajolu2rh	11	18	-	-	HYPH
cord-322166-ajolu2rh	11	19	sense	sense	NN
cord-322166-ajolu2rh	11	20	RNAs	rna	NNS
cord-322166-ajolu2rh	11	21	consisting	consist	VBG
cord-322166-ajolu2rh	11	22	of	of	IN
cord-322166-ajolu2rh	11	23	from	from	IN
cord-322166-ajolu2rh	11	24	890	890	CD
cord-322166-ajolu2rh	11	25	to	to	IN
cord-322166-ajolu2rh	11	26	2,341	2,341	CD
cord-322166-ajolu2rh	11	27	nucleotides	nucleotide	NNS
cord-322166-ajolu2rh	11	28	(	(	-LRB-
cord-322166-ajolu2rh	11	29	Noda	Noda	NNP
cord-322166-ajolu2rh	11	30	T	T	NNP
cord-322166-ajolu2rh	11	31	,	,	,
cord-322166-ajolu2rh	11	32	et	et	NNP
cord-322166-ajolu2rh	11	33	al	al	NNP
cord-322166-ajolu2rh	11	34	.	.	NNP
cord-322166-ajolu2rh	11	35	,	,	,
cord-322166-ajolu2rh	11	36	2006	2006	CD
cord-322166-ajolu2rh	11	37	)	)	-RRB-
cord-322166-ajolu2rh	11	38	.	.	.
cord-322166-ajolu2rh	12	1	Avian	avian	JJ
cord-322166-ajolu2rh	12	2	influenza	influenza	NN
cord-322166-ajolu2rh	12	3	virus	virus	NN
cord-322166-ajolu2rh	12	4	(	(	-LRB-
cord-322166-ajolu2rh	12	5	AIV	AIV	NNP
cord-322166-ajolu2rh	12	6	)	)	-RRB-
cord-322166-ajolu2rh	12	7	is	be	VBZ
cord-322166-ajolu2rh	12	8	a	a	DT
cord-322166-ajolu2rh	12	9	type	type	NN
cord-322166-ajolu2rh	12	10	A	a	DT
cord-322166-ajolu2rh	12	11	virus	virus	NN
cord-322166-ajolu2rh	12	12	that	that	WDT
cord-322166-ajolu2rh	12	13	has	have	VBZ
cord-322166-ajolu2rh	12	14	eight	eight	CD
cord-322166-ajolu2rh	12	15	gene	gene	NN
cord-322166-ajolu2rh	12	16	segments	segment	NNS
cord-322166-ajolu2rh	12	17	encoding	encode	VBG
cord-322166-ajolu2rh	12	18	11	11	CD
cord-322166-ajolu2rh	12	19	-	-	SYM
cord-322166-ajolu2rh	12	20	12	12	CD
cord-322166-ajolu2rh	12	21	proteins	protein	NNS
cord-322166-ajolu2rh	12	22	:	:	:
cord-322166-ajolu2rh	12	23	hemagglutinin	hemagglutinin	NN
cord-322166-ajolu2rh	12	24	(	(	-LRB-
cord-322166-ajolu2rh	12	25	HA	HA	NNP
cord-322166-ajolu2rh	12	26	)	)	-RRB-
cord-322166-ajolu2rh	12	27	,	,	,
cord-322166-ajolu2rh	12	28	neuraminidase	neuraminidase	FW
cord-322166-ajolu2rh	12	29	(	(	-LRB-
cord-322166-ajolu2rh	12	30	NA	NA	NNP
cord-322166-ajolu2rh	12	31	)	)	-RRB-
cord-322166-ajolu2rh	12	32	,	,	,
cord-322166-ajolu2rh	12	33	matrix	matrix	NN
cord-322166-ajolu2rh	12	34	proteins	protein	NNS
cord-322166-ajolu2rh	12	35	(	(	-LRB-
cord-322166-ajolu2rh	12	36	M1	M1	NNP
cord-322166-ajolu2rh	12	37	and	and	CC
cord-322166-ajolu2rh	12	38	M2	M2	NNP
cord-322166-ajolu2rh	12	39	)	)	-RRB-
cord-322166-ajolu2rh	12	40	,	,	,
cord-322166-ajolu2rh	12	41	non	non	JJ
cord-322166-ajolu2rh	12	42	-	-	JJ
cord-322166-ajolu2rh	12	43	structural	structural	JJ
cord-322166-ajolu2rh	12	44	proteins	protein	NNS
cord-322166-ajolu2rh	12	45	(	(	-LRB-
cord-322166-ajolu2rh	12	46	NS1	NS1	NNS
cord-322166-ajolu2rh	12	47	and	and	CC
cord-322166-ajolu2rh	12	48	NS2	NS2	NNP
cord-322166-ajolu2rh	12	49	)	)	-RRB-
cord-322166-ajolu2rh	12	50	,	,	,
cord-322166-ajolu2rh	12	51	nucleocapsid	nucleocapsid	NN
cord-322166-ajolu2rh	12	52	proteins	protein	NNS
cord-322166-ajolu2rh	12	53	(	(	-LRB-
cord-322166-ajolu2rh	12	54	NP	NP	NNP
cord-322166-ajolu2rh	12	55	)	)	-RRB-
cord-322166-ajolu2rh	12	56	,	,	,
cord-322166-ajolu2rh	12	57	and	and	CC
cord-322166-ajolu2rh	12	58	three	three	CD
cord-322166-ajolu2rh	12	59	polymerases	polymerase	NNS
cord-322166-ajolu2rh	12	60	,	,	,
cord-322166-ajolu2rh	13	1	polymerase	polymerase	NNP
cord-322166-ajolu2rh	13	2	basic	basic	NNP
cord-322166-ajolu2rh	13	3	1	1	CD
cord-322166-ajolu2rh	13	4	(	(	-LRB-
cord-322166-ajolu2rh	13	5	PB1	pb1	NN
cord-322166-ajolu2rh	13	6	)	)	-RRB-
cord-322166-ajolu2rh	14	1	,	,	,
cord-322166-ajolu2rh	14	2	polymerase	polymerase	VB
cord-322166-ajolu2rh	14	3	basic	basic	JJ
cord-322166-ajolu2rh	14	4	2	2	CD
cord-322166-ajolu2rh	14	5	(	(	-LRB-
cord-322166-ajolu2rh	14	6	PB2	PB2	NNP
cord-322166-ajolu2rh	14	7	)	)	-RRB-
cord-322166-ajolu2rh	14	8	and	and	CC
cord-322166-ajolu2rh	14	9	polymerase	polymerase	VB
cord-322166-ajolu2rh	14	10	acidic	acidic	JJ
cord-322166-ajolu2rh	14	11	(	(	-LRB-
cord-322166-ajolu2rh	14	12	PA	PA	NNP
cord-322166-ajolu2rh	14	13	)	)	-RRB-
cord-322166-ajolu2rh	14	14	proteins	protein	NNS
cord-322166-ajolu2rh	14	15	.	.	.
cord-322166-ajolu2rh	15	1	Another	another	DT
cord-322166-ajolu2rh	15	2	protein	protein	NN
cord-322166-ajolu2rh	15	3	,	,	,
cord-322166-ajolu2rh	15	4	N40	N40	NNP
cord-322166-ajolu2rh	15	5	,	,	,
cord-322166-ajolu2rh	15	6	which	which	WDT
cord-322166-ajolu2rh	15	7	is	be	VBZ
cord-322166-ajolu2rh	15	8	encoded	encode	VBN
cord-322166-ajolu2rh	15	9	by	by	IN
cord-322166-ajolu2rh	15	10	the	the	DT
cord-322166-ajolu2rh	15	11	PB2	PB2	NNP
cord-322166-ajolu2rh	15	12	segment	segment	NN
cord-322166-ajolu2rh	15	13	,	,	,
cord-322166-ajolu2rh	15	14	has	have	VBZ
cord-322166-ajolu2rh	15	15	been	be	VBN
cord-322166-ajolu2rh	15	16	identified	identify	VBN
cord-322166-ajolu2rh	15	17	recently	recently	RB
cord-322166-ajolu2rh	16	1	(	(	-LRB-
cord-322166-ajolu2rh	16	2	Medina	Medina	NNP
cord-322166-ajolu2rh	16	3	R	R	NNP
cord-322166-ajolu2rh	16	4	A	A	NNP
cord-322166-ajolu2rh	16	5	,	,	,
cord-322166-ajolu2rh	16	6	et	et	FW
cord-322166-ajolu2rh	16	7	al	al	NNP
cord-322166-ajolu2rh	16	8	.	.	.
cord-322166-ajolu2rh	17	1	,	,	,
cord-322166-ajolu2rh	17	2	2011	2011	CD
cord-322166-ajolu2rh	17	3	;	;	:
cord-322166-ajolu2rh	17	4	Webster	Webster	NNP
cord-322166-ajolu2rh	17	5	R	R	NNP
cord-322166-ajolu2rh	17	6	G	G	NNP
cord-322166-ajolu2rh	17	7	,	,	,
cord-322166-ajolu2rh	17	8	et	et	NNP
cord-322166-ajolu2rh	17	9	al	al	NNP
cord-322166-ajolu2rh	17	10	.	.	NNP
cord-322166-ajolu2rh	17	11	,	,	,
cord-322166-ajolu2rh	17	12	1992	1992	CD
cord-322166-ajolu2rh	17	13	;	;	:
cord-322166-ajolu2rh	17	14	Wise	Wise	NNP
cord-322166-ajolu2rh	17	15	H	H	NNP
cord-322166-ajolu2rh	17	16	M	M	NNP
cord-322166-ajolu2rh	17	17	,	,	,
cord-322166-ajolu2rh	17	18	et	et	NNP
cord-322166-ajolu2rh	17	19	al	al	NNP
cord-322166-ajolu2rh	17	20	.	.	NNP
cord-322166-ajolu2rh	17	21	,	,	,
cord-322166-ajolu2rh	17	22	2009	2009	CD
cord-322166-ajolu2rh	17	23	)	)	-RRB-
cord-322166-ajolu2rh	17	24	.	.	.
cord-322166-ajolu2rh	18	1	Some	some	DT
cord-322166-ajolu2rh	18	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	18	3	viruses	virus	NNS
cord-322166-ajolu2rh	18	4	also	also	RB
cord-322166-ajolu2rh	18	5	express	express	VBP
cord-322166-ajolu2rh	18	6	the	the	DT
cord-322166-ajolu2rh	18	7	pro	pro	JJ
cord-322166-ajolu2rh	18	8	-	-	JJ
cord-322166-ajolu2rh	18	9	apoptotic	apoptotic	JJ
cord-322166-ajolu2rh	18	10	protein	protein	NN
cord-322166-ajolu2rh	18	11	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	18	12	,	,	,
cord-322166-ajolu2rh	18	13	which	which	WDT
cord-322166-ajolu2rh	18	14	is	be	VBZ
cord-322166-ajolu2rh	18	15	encoded	encode	VBN
cord-322166-ajolu2rh	18	16	by	by	IN
cord-322166-ajolu2rh	18	17	the	the	DT
cord-322166-ajolu2rh	18	18	PB1	PB1	NNP
cord-322166-ajolu2rh	18	19	segment	segment	NN
cord-322166-ajolu2rh	18	20	(	(	-LRB-
cord-322166-ajolu2rh	18	21	Chen	Chen	NNP
cord-322166-ajolu2rh	18	22	W	W	NNP
cord-322166-ajolu2rh	18	23	,	,	,
cord-322166-ajolu2rh	18	24	et	et	NNP
cord-322166-ajolu2rh	18	25	al	al	NNP
cord-322166-ajolu2rh	18	26	.	.	NNP
cord-322166-ajolu2rh	18	27	,	,	,
cord-322166-ajolu2rh	18	28	2001	2001	CD
cord-322166-ajolu2rh	18	29	;	;	:
cord-322166-ajolu2rh	18	30	Medina	Medina	NNP
cord-322166-ajolu2rh	18	31	R	R	NNP
cord-322166-ajolu2rh	18	32	A	A	NNP
cord-322166-ajolu2rh	18	33	,	,	,
cord-322166-ajolu2rh	18	34	et	et	NNP
cord-322166-ajolu2rh	18	35	al	al	NNP
cord-322166-ajolu2rh	18	36	.	.	NNP
cord-322166-ajolu2rh	18	37	,	,	,
cord-322166-ajolu2rh	18	38	2011	2011	CD
cord-322166-ajolu2rh	18	39	)	)	-RRB-
cord-322166-ajolu2rh	19	1	(	(	-LRB-
cord-322166-ajolu2rh	19	2	Table	table	NN
cord-322166-ajolu2rh	19	3	1	1	CD
cord-322166-ajolu2rh	19	4	)	)	-RRB-
cord-322166-ajolu2rh	19	5	.	.	.
cord-322166-ajolu2rh	20	1	The	the	DT
cord-322166-ajolu2rh	20	2	type	type	NN
cord-322166-ajolu2rh	20	3	A	a	DT
cord-322166-ajolu2rh	20	4	influenza	influenza	NN
cord-322166-ajolu2rh	20	5	viruses	virus	NNS
cord-322166-ajolu2rh	20	6	are	be	VBP
cord-322166-ajolu2rh	20	7	divided	divide	VBN
cord-322166-ajolu2rh	20	8	into	into	IN
cord-322166-ajolu2rh	20	9	subtypes	subtype	NNS
cord-322166-ajolu2rh	20	10	by	by	IN
cord-322166-ajolu2rh	20	11	two	two	CD
cord-322166-ajolu2rh	20	12	envelope	envelope	NN
cord-322166-ajolu2rh	20	13	proteins	protein	NNS
cord-322166-ajolu2rh	20	14	:	:	:
cord-322166-ajolu2rh	20	15	hemagglutinin	hemagglutinin	NN
cord-322166-ajolu2rh	20	16	(	(	-LRB-
cord-322166-ajolu2rh	20	17	HA	HA	NNP
cord-322166-ajolu2rh	20	18	)	)	-RRB-
cord-322166-ajolu2rh	20	19	and	and	CC
cord-322166-ajolu2rh	20	20	neuraminidase	neuraminidase	NN
cord-322166-ajolu2rh	20	21	(	(	-LRB-
cord-322166-ajolu2rh	20	22	NA	NA	NNP
cord-322166-ajolu2rh	20	23	)	)	-RRB-
cord-322166-ajolu2rh	20	24	.	.	.
cord-322166-ajolu2rh	21	1	To	to	IN
cord-322166-ajolu2rh	21	2	date	date	NN
cord-322166-ajolu2rh	21	3	,	,	,
cord-322166-ajolu2rh	21	4	16	16	CD
cord-322166-ajolu2rh	21	5	HA	HA	NNP
cord-322166-ajolu2rh	21	6	subtypes	subtype	NNS
cord-322166-ajolu2rh	21	7	(	(	-LRB-
cord-322166-ajolu2rh	21	8	H1	h1	NN
cord-322166-ajolu2rh	21	9	to	to	IN
cord-322166-ajolu2rh	21	10	H16	H16	NNP
cord-322166-ajolu2rh	21	11	)	)	-RRB-
cord-322166-ajolu2rh	21	12	and	and	CC
cord-322166-ajolu2rh	21	13	nine	nine	CD
cord-322166-ajolu2rh	21	14	NA	NA	NNP
cord-322166-ajolu2rh	21	15	subtypes	subtype	NNS
cord-322166-ajolu2rh	21	16	(	(	-LRB-
cord-322166-ajolu2rh	21	17	N1	n1	NN
cord-322166-ajolu2rh	21	18	to	to	IN
cord-322166-ajolu2rh	21	19	N9	N9	NNP
cord-322166-ajolu2rh	21	20	)	)	-RRB-
cord-322166-ajolu2rh	21	21	have	have	VBP
cord-322166-ajolu2rh	21	22	been	be	VBN
cord-322166-ajolu2rh	21	23	detected	detect	VBN
cord-322166-ajolu2rh	21	24	in	in	IN
cord-322166-ajolu2rh	21	25	birds	bird	NNS
cord-322166-ajolu2rh	21	26	(	(	-LRB-
cord-322166-ajolu2rh	21	27	Webster	Webster	NNP
cord-322166-ajolu2rh	21	28	R	R	NNP
cord-322166-ajolu2rh	21	29	G	G	NNP
cord-322166-ajolu2rh	21	30	,	,	,
cord-322166-ajolu2rh	21	31	et	et	NNP
cord-322166-ajolu2rh	21	32	al	al	NNP
cord-322166-ajolu2rh	21	33	.	.	NNP
cord-322166-ajolu2rh	21	34	,	,	,
cord-322166-ajolu2rh	21	35	1992	1992	CD
cord-322166-ajolu2rh	21	36	)	)	-RRB-
cord-322166-ajolu2rh	21	37	.	.	.
cord-322166-ajolu2rh	22	1	Many	many	JJ
cord-322166-ajolu2rh	22	2	species	specie	NNS
cord-322166-ajolu2rh	22	3	of	of	IN
cord-322166-ajolu2rh	22	4	shorebirds	shorebird	NNS
cord-322166-ajolu2rh	22	5	and	and	CC
cord-322166-ajolu2rh	22	6	other	other	JJ
cord-322166-ajolu2rh	22	7	waterfowl	waterfowl	NNS
cord-322166-ajolu2rh	22	8	(	(	-LRB-
cord-322166-ajolu2rh	22	9	e.g.	e.g.	RB
cord-322166-ajolu2rh	22	10	,	,	,
cord-322166-ajolu2rh	22	11	wild	wild	JJ
cord-322166-ajolu2rh	22	12	geese	goose	NNS
cord-322166-ajolu2rh	22	13	,	,	,
cord-322166-ajolu2rh	22	14	ducks	duck	NNS
cord-322166-ajolu2rh	22	15	)	)	-RRB-
cord-322166-ajolu2rh	22	16	are	be	VBP
cord-322166-ajolu2rh	22	17	natural	natural	JJ
cord-322166-ajolu2rh	22	18	reservoirs	reservoir	NNS
cord-322166-ajolu2rh	22	19	of	of	IN
cord-322166-ajolu2rh	22	20	AIV	AIV	NNP
cord-322166-ajolu2rh	22	21	(	(	-LRB-
cord-322166-ajolu2rh	22	22	Webster	Webster	NNP
cord-322166-ajolu2rh	22	23	R	R	NNP
cord-322166-ajolu2rh	22	24	G	G	NNP
cord-322166-ajolu2rh	22	25	,	,	,
cord-322166-ajolu2rh	22	26	et	et	NNP
cord-322166-ajolu2rh	22	27	al	al	NNP
cord-322166-ajolu2rh	22	28	.	.	NNP
cord-322166-ajolu2rh	22	29	,	,	,
cord-322166-ajolu2rh	22	30	1992	1992	CD
cord-322166-ajolu2rh	22	31	)	)	-RRB-
cord-322166-ajolu2rh	22	32	.	.	.
cord-322166-ajolu2rh	23	1	Most	Most	JJS
cord-322166-ajolu2rh	23	2	AIV	AIV	NNP
cord-322166-ajolu2rh	23	3	subtypes	subtype	NNS
cord-322166-ajolu2rh	23	4	appear	appear	VBP
cord-322166-ajolu2rh	23	5	non	non	JJ
cord-322166-ajolu2rh	23	6	-	-	JJ
cord-322166-ajolu2rh	23	7	virulent	virulent	JJ
cord-322166-ajolu2rh	23	8	to	to	IN
cord-322166-ajolu2rh	23	9	birds	bird	NNS
cord-322166-ajolu2rh	23	10	,	,	,
cord-322166-ajolu2rh	23	11	since	since	IN
cord-322166-ajolu2rh	23	12	infected	infect	VBN
cord-322166-ajolu2rh	23	13	birds	bird	NNS
cord-322166-ajolu2rh	23	14	generally	generally	RB
cord-322166-ajolu2rh	23	15	show	show	VBP
cord-322166-ajolu2rh	23	16	no	no	DT
cord-322166-ajolu2rh	23	17	clinical	clinical	JJ
cord-322166-ajolu2rh	23	18	symptoms	symptom	NNS
cord-322166-ajolu2rh	23	19	of	of	IN
cord-322166-ajolu2rh	23	20	infection	infection	NN
cord-322166-ajolu2rh	23	21	(	(	-LRB-
cord-322166-ajolu2rh	23	22	de	de	FW
cord-322166-ajolu2rh	23	23	Jong	Jong	NNP
cord-322166-ajolu2rh	23	24	M	M	NNP
cord-322166-ajolu2rh	23	25	D	D	NNP
cord-322166-ajolu2rh	23	26	,	,	,
cord-322166-ajolu2rh	23	27	et	et	NNP
cord-322166-ajolu2rh	23	28	al	al	NNP
cord-322166-ajolu2rh	23	29	.	.	NNP
cord-322166-ajolu2rh	23	30	,	,	,
cord-322166-ajolu2rh	23	31	2006	2006	CD
cord-322166-ajolu2rh	23	32	;	;	:
cord-322166-ajolu2rh	23	33	Webster	Webster	NNP
cord-322166-ajolu2rh	23	34	R	R	NNP
cord-322166-ajolu2rh	23	35	G	G	NNP
cord-322166-ajolu2rh	23	36	,	,	,
cord-322166-ajolu2rh	23	37	et	et	NNP
cord-322166-ajolu2rh	23	38	al	al	NNP
cord-322166-ajolu2rh	23	39	.	.	NNP
cord-322166-ajolu2rh	23	40	,	,	,
cord-322166-ajolu2rh	23	41	1992	1992	CD
cord-322166-ajolu2rh	23	42	)	)	-RRB-
cord-322166-ajolu2rh	23	43	.	.	.
cord-322166-ajolu2rh	24	1	Although	although	IN
cord-322166-ajolu2rh	24	2	the	the	DT
cord-322166-ajolu2rh	24	3	majority	majority	NN
cord-322166-ajolu2rh	24	4	of	of	IN
cord-322166-ajolu2rh	24	5	the	the	DT
cord-322166-ajolu2rh	24	6	known	know	VBN
cord-322166-ajolu2rh	24	7	avian	avian	JJ
cord-322166-ajolu2rh	24	8	influenza	influenza	NN
cord-322166-ajolu2rh	24	9	A	a	DT
cord-322166-ajolu2rh	24	10	virus	virus	NN
cord-322166-ajolu2rh	24	11	subtypes	subtype	NNS
cord-322166-ajolu2rh	24	12	have	have	VBP
cord-322166-ajolu2rh	24	13	only	only	RB
cord-322166-ajolu2rh	24	14	been	be	VBN
cord-322166-ajolu2rh	24	15	isolated	isolate	VBN
cord-322166-ajolu2rh	24	16	from	from	IN
cord-322166-ajolu2rh	24	17	wild	wild	JJ
cord-322166-ajolu2rh	24	18	birds	bird	NNS
cord-322166-ajolu2rh	24	19	,	,	,
cord-322166-ajolu2rh	24	20	they	-PRON-	PRP
cord-322166-ajolu2rh	24	21	have	have	VBP
cord-322166-ajolu2rh	24	22	spread	spread	VBN
cord-322166-ajolu2rh	24	23	among	among	IN
cord-322166-ajolu2rh	24	24	marine	marine	JJ
cord-322166-ajolu2rh	24	25	mammals	mammal	NNS
cord-322166-ajolu2rh	24	26	,	,	,
cord-322166-ajolu2rh	24	27	including	include	VBG
cord-322166-ajolu2rh	24	28	seals	seal	NNS
cord-322166-ajolu2rh	24	29	and	and	CC
cord-322166-ajolu2rh	24	30	whales	whale	NNS
cord-322166-ajolu2rh	24	31	,	,	,
cord-322166-ajolu2rh	24	32	swine	swine	NN
cord-322166-ajolu2rh	24	33	,	,	,
cord-322166-ajolu2rh	24	34	dogs	dog	NNS
cord-322166-ajolu2rh	24	35	,	,	,
cord-322166-ajolu2rh	24	36	cats	cat	NNS
cord-322166-ajolu2rh	24	37	,	,	,
cord-322166-ajolu2rh	24	38	and	and	CC
cord-322166-ajolu2rh	24	39	horses	horse	NNS
cord-322166-ajolu2rh	25	1	(	(	-LRB-
cord-322166-ajolu2rh	25	2	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	25	3	M	M	NNP
cord-322166-ajolu2rh	25	4	J	J	NNP
cord-322166-ajolu2rh	25	5	,	,	,
cord-322166-ajolu2rh	25	6	2010	2010	CD
cord-322166-ajolu2rh	25	7	;	;	:
cord-322166-ajolu2rh	25	8	Suarez	Suarez	NNP
cord-322166-ajolu2rh	25	9	D	D	NNP
cord-322166-ajolu2rh	25	10	L	L	NNP
cord-322166-ajolu2rh	25	11	,	,	,
cord-322166-ajolu2rh	25	12	et	et	NNP
cord-322166-ajolu2rh	25	13	al	al	NNP
cord-322166-ajolu2rh	25	14	.	.	NNP
cord-322166-ajolu2rh	25	15	,	,	,
cord-322166-ajolu2rh	25	16	2000	2000	CD
cord-322166-ajolu2rh	25	17	)	)	-RRB-
cord-322166-ajolu2rh	25	18	.	.	.
cord-322166-ajolu2rh	26	1	Currently	currently	RB
cord-322166-ajolu2rh	26	2	,	,	,
cord-322166-ajolu2rh	26	3	five	five	CD
cord-322166-ajolu2rh	26	4	AIV	AIV	NNP
cord-322166-ajolu2rh	26	5	subtypes	subtype	NNS
cord-322166-ajolu2rh	26	6	[	[	-LRB-
cord-322166-ajolu2rh	26	7	H1N1	H1N1	NNP
cord-322166-ajolu2rh	26	8	,	,	,
cord-322166-ajolu2rh	26	9	H3N2	H3N2	NNP
cord-322166-ajolu2rh	26	10	,	,	,
cord-322166-ajolu2rh	26	11	H2N2	H2N2	NNP
cord-322166-ajolu2rh	26	12	,	,	,
cord-322166-ajolu2rh	26	13	H1N2	H1N2	NNP
cord-322166-ajolu2rh	26	14	and	and	CC
cord-322166-ajolu2rh	26	15	the	the	DT
cord-322166-ajolu2rh	26	16	highly	highly	RB
cord-322166-ajolu2rh	26	17	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	26	18	H5N1	H5N1	NNP
cord-322166-ajolu2rh	26	19	]	]	-RRB-
cord-322166-ajolu2rh	26	20	replicate	replicate	VB
cord-322166-ajolu2rh	26	21	efficiently	efficiently	RB
cord-322166-ajolu2rh	26	22	in	in	IN
cord-322166-ajolu2rh	26	23	human	human	JJ
cord-322166-ajolu2rh	26	24	cells	cell	NNS
cord-322166-ajolu2rh	26	25	,	,	,
cord-322166-ajolu2rh	26	26	resulting	result	VBG
cord-322166-ajolu2rh	26	27	in	in	IN
cord-322166-ajolu2rh	26	28	greater	great	JJR
cord-322166-ajolu2rh	26	29	potential	potential	NN
cord-322166-ajolu2rh	26	30	for	for	IN
cord-322166-ajolu2rh	26	31	an	an	DT
cord-322166-ajolu2rh	26	32	AIV	AIV	NNP
cord-322166-ajolu2rh	26	33	pandemic	pandemic	NN
cord-322166-ajolu2rh	26	34	among	among	IN
cord-322166-ajolu2rh	26	35	humans	human	NNS
cord-322166-ajolu2rh	26	36	(	(	-LRB-
cord-322166-ajolu2rh	26	37	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	26	38	M	M	NNP
cord-322166-ajolu2rh	26	39	J	J	NNP
cord-322166-ajolu2rh	26	40	,	,	,
cord-322166-ajolu2rh	26	41	2010	2010	CD
cord-322166-ajolu2rh	26	42	)	)	-RRB-
cord-322166-ajolu2rh	26	43	.	.	.
cord-322166-ajolu2rh	27	1	Outbreaks	outbreak	NNS
cord-322166-ajolu2rh	27	2	of	of	IN
cord-322166-ajolu2rh	27	3	highly	highly	RB
cord-322166-ajolu2rh	27	4	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	27	5	avian	avian	JJ
cord-322166-ajolu2rh	27	6	influenza	influenza	NN
cord-322166-ajolu2rh	27	7	(	(	-LRB-
cord-322166-ajolu2rh	27	8	HPAI	HPAI	NNP
cord-322166-ajolu2rh	27	9	)	)	-RRB-
cord-322166-ajolu2rh	28	1	H5N1	H5N1	NNP
cord-322166-ajolu2rh	28	2	virus	virus	NN
cord-322166-ajolu2rh	28	3	infections	infection	NNS
cord-322166-ajolu2rh	28	4	were	be	VBD
cord-322166-ajolu2rh	28	5	first	first	RB
cord-322166-ajolu2rh	28	6	recorded	record	VBN
cord-322166-ajolu2rh	28	7	in	in	IN
cord-322166-ajolu2rh	28	8	poultry	poultry	NN
cord-322166-ajolu2rh	28	9	in	in	IN
cord-322166-ajolu2rh	28	10	Guangdong	Guangdong	NNP
cord-322166-ajolu2rh	28	11	,	,	,
cord-322166-ajolu2rh	28	12	China	China	NNP
cord-322166-ajolu2rh	28	13	in	in	IN
cord-322166-ajolu2rh	28	14	1996	1996	CD
cord-322166-ajolu2rh	28	15	.	.	.
cord-322166-ajolu2rh	29	1	It	-PRON-	PRP
cord-322166-ajolu2rh	29	2	is	be	VBZ
cord-322166-ajolu2rh	29	3	now	now	RB
cord-322166-ajolu2rh	29	4	suspected	suspect	VBN
cord-322166-ajolu2rh	29	5	that	that	IN
cord-322166-ajolu2rh	29	6	this	this	DT
cord-322166-ajolu2rh	29	7	virus	virus	NN
cord-322166-ajolu2rh	29	8	contained	contain	VBD
cord-322166-ajolu2rh	29	9	only	only	RB
cord-322166-ajolu2rh	29	10	a	a	DT
cord-322166-ajolu2rh	29	11	few	few	JJ
cord-322166-ajolu2rh	29	12	HA	HA	NNP
cord-322166-ajolu2rh	29	13	gene	gene	NN
cord-322166-ajolu2rh	29	14	mutations	mutation	NNS
cord-322166-ajolu2rh	29	15	that	that	WDT
cord-322166-ajolu2rh	29	16	were	be	VBD
cord-322166-ajolu2rh	29	17	not	not	RB
cord-322166-ajolu2rh	29	18	present	present	JJ
cord-322166-ajolu2rh	29	19	in	in	IN
cord-322166-ajolu2rh	29	20	the	the	DT
cord-322166-ajolu2rh	29	21	HA	HA	NNP
cord-322166-ajolu2rh	29	22	of	of	IN
cord-322166-ajolu2rh	29	23	a	a	DT
cord-322166-ajolu2rh	29	24	low	low	JJ
cord-322166-ajolu2rh	29	25	pandemic	pandemic	NN
cord-322166-ajolu2rh	29	26	avian	avian	JJ
cord-322166-ajolu2rh	29	27	influenza	influenza	NN
cord-322166-ajolu2rh	29	28	4	4	CD
cord-322166-ajolu2rh	29	29	Non	non	JJ
cord-322166-ajolu2rh	29	30	-	-	JJ
cord-322166-ajolu2rh	29	31	structure	structure	NN
cord-322166-ajolu2rh	29	32	protein	protein	NN
cord-322166-ajolu2rh	29	33	1	1	CD
cord-322166-ajolu2rh	29	34	involved	involve	VBN
cord-322166-ajolu2rh	29	35	in	in	IN
cord-322166-ajolu2rh	29	36	the	the	DT
cord-322166-ajolu2rh	29	37	post	post	JJ
cord-322166-ajolu2rh	29	38	-	-	JJ
cord-322166-ajolu2rh	29	39	transcription	transcription	JJ
cord-322166-ajolu2rh	29	40	,	,	,
cord-322166-ajolu2rh	29	41	host	host	NN
cord-322166-ajolu2rh	29	42	antiviral	antiviral	JJ
cord-322166-ajolu2rh	29	43	response	response	NN
cord-322166-ajolu2rh	29	44	antagonist	antagonist	NN
cord-322166-ajolu2rh	29	45	NS2	NS2	NNP
cord-322166-ajolu2rh	29	46	(	(	-LRB-
cord-322166-ajolu2rh	29	47	NEP	NEP	NNP
cord-322166-ajolu2rh	29	48	)	)	-RRB-
cord-322166-ajolu2rh	29	49	Nuclear	nuclear	JJ
cord-322166-ajolu2rh	29	50	export	export	NN
cord-322166-ajolu2rh	29	51	protein	protein	NN
cord-322166-ajolu2rh	29	52	which	which	WDT
cord-322166-ajolu2rh	29	53	regulates	regulate	VBZ
cord-322166-ajolu2rh	29	54	the	the	DT
cord-322166-ajolu2rh	29	55	virus	virus	NN
cord-322166-ajolu2rh	29	56	transcription	transcription	NN
cord-322166-ajolu2rh	29	57	and	and	CC
cord-322166-ajolu2rh	29	58	replication	replication	NN
cord-322166-ajolu2rh	29	59	PB1	PB1	NNP
cord-322166-ajolu2rh	29	60	Core	Core	NNP
cord-322166-ajolu2rh	29	61	subunit	subunit	NN
cord-322166-ajolu2rh	29	62	of	of	IN
cord-322166-ajolu2rh	29	63	RNA	RNA	NNP
cord-322166-ajolu2rh	29	64	-	-	HYPH
cord-322166-ajolu2rh	29	65	dependent	dependent	JJ
cord-322166-ajolu2rh	29	66	RNA	RNA	NNP
cord-322166-ajolu2rh	29	67	polymerase	polymerase	NN
cord-322166-ajolu2rh	29	68	involved	involve	VBN
cord-322166-ajolu2rh	29	69	in	in	IN
cord-322166-ajolu2rh	29	70	RNA	RNA	NNP
cord-322166-ajolu2rh	29	71	transcription	transcription	NN
cord-322166-ajolu2rh	29	72	and	and	CC
cord-322166-ajolu2rh	29	73	replication	replication	NN
cord-322166-ajolu2rh	29	74	;	;	:
cord-322166-ajolu2rh	29	75	contains	contain	VBZ
cord-322166-ajolu2rh	29	76	the	the	DT
cord-322166-ajolu2rh	29	77	polymerase	polymerase	NN
cord-322166-ajolu2rh	29	78	activity	activity	NN
cord-322166-ajolu2rh	29	79	PB2	PB2	NNP
cord-322166-ajolu2rh	29	80	Component	Component	NNP
cord-322166-ajolu2rh	29	81	of	of	IN
cord-322166-ajolu2rh	29	82	the	the	DT
cord-322166-ajolu2rh	29	83	RNA	RNA	NNP
cord-322166-ajolu2rh	29	84	-	-	HYPH
cord-322166-ajolu2rh	29	85	dependent	dependent	JJ
cord-322166-ajolu2rh	29	86	RNA	RNA	NNP
cord-322166-ajolu2rh	29	87	polymerase	polymerase	NN
cord-322166-ajolu2rh	29	88	involved	involve	VBN
cord-322166-ajolu2rh	29	89	in	in	IN
cord-322166-ajolu2rh	29	90	RNA	RNA	NNP
cord-322166-ajolu2rh	29	91	transcription	transcription	NN
cord-322166-ajolu2rh	29	92	;	;	:
cord-322166-ajolu2rh	29	93	has	have	VBZ
cord-322166-ajolu2rh	29	94	the	the	DT
cord-322166-ajolu2rh	29	95	temperature	temperature	NN
cord-322166-ajolu2rh	29	96	-	-	HYPH
cord-322166-ajolu2rh	29	97	dependent	dependent	JJ
cord-322166-ajolu2rh	29	98	replication	replication	NN
cord-322166-ajolu2rh	29	99	competence	competence	NN
cord-322166-ajolu2rh	29	100	;	;	:
cord-322166-ajolu2rh	29	101	recognizes	recognize	VBZ
cord-322166-ajolu2rh	29	102	capped	cap	VBN
cord-322166-ajolu2rh	29	103	cellular	cellular	JJ
cord-322166-ajolu2rh	29	104	mRNA	mrna	NN
cord-322166-ajolu2rh	29	105	N40	N40	NNP
cord-322166-ajolu2rh	29	106	Unknown	unknown	JJ
cord-322166-ajolu2rh	29	107	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	29	108	Induction	Induction	NNP
cord-322166-ajolu2rh	29	109	of	of	IN
cord-322166-ajolu2rh	29	110	apoptosis	apoptosis	NN
cord-322166-ajolu2rh	29	111	;	;	:
cord-322166-ajolu2rh	29	112	promotion	promotion	NN
cord-322166-ajolu2rh	29	113	of	of	IN
cord-322166-ajolu2rh	29	114	secondary	secondary	JJ
cord-322166-ajolu2rh	29	115	bacterial	bacterial	JJ
cord-322166-ajolu2rh	29	116	infection	infection	NN
cord-322166-ajolu2rh	29	117	PA	PA	NNP
cord-322166-ajolu2rh	29	118	Component	Component	NNP
cord-322166-ajolu2rh	29	119	of	of	IN
cord-322166-ajolu2rh	29	120	the	the	DT
cord-322166-ajolu2rh	29	121	RNA	RNA	NNP
cord-322166-ajolu2rh	29	122	-	-	HYPH
cord-322166-ajolu2rh	29	123	dependent	dependent	JJ
cord-322166-ajolu2rh	29	124	RNA	RNA	NNP
cord-322166-ajolu2rh	29	125	polymerase	polymerase	NN
cord-322166-ajolu2rh	29	126	involved	involve	VBN
cord-322166-ajolu2rh	29	127	in	in	IN
cord-322166-ajolu2rh	29	128	RNA	RNA	NNP
cord-322166-ajolu2rh	29	129	replication	replication	NN
cord-322166-ajolu2rh	29	130	;	;	:
cord-322166-ajolu2rh	29	131	possesses	possess	VBZ
cord-322166-ajolu2rh	29	132	an	an	DT
cord-322166-ajolu2rh	29	133	endonuclease	endonuclease	NN
cord-322166-ajolu2rh	29	134	activity	activity	NN
cord-322166-ajolu2rh	29	135	M1	M1	NNP
cord-322166-ajolu2rh	29	136	Membrane	Membrane	NNP
cord-322166-ajolu2rh	29	137	matrix	matrix	NN
cord-322166-ajolu2rh	29	138	protein	protein	NN
cord-322166-ajolu2rh	29	139	M2	M2	NNP
cord-322166-ajolu2rh	29	140	Membrane	Membrane	NNP
cord-322166-ajolu2rh	29	141	ion	ion	NN
cord-322166-ajolu2rh	29	142	channel	channel	NN
cord-322166-ajolu2rh	29	143	protein	protein	NN
cord-322166-ajolu2rh	30	1	The	the	DT
cord-322166-ajolu2rh	30	2	table	table	NN
cord-322166-ajolu2rh	30	3	lists	list	VBZ
cord-322166-ajolu2rh	30	4	all	all	DT
cord-322166-ajolu2rh	30	5	12	12	CD
cord-322166-ajolu2rh	30	6	proteins	protein	NNS
cord-322166-ajolu2rh	30	7	encoded	encode	VBN
cord-322166-ajolu2rh	30	8	by	by	IN
cord-322166-ajolu2rh	30	9	influenza	influenza	NN
cord-322166-ajolu2rh	30	10	A	a	DT
cord-322166-ajolu2rh	30	11	virus	virus	NN
cord-322166-ajolu2rh	30	12	genome	genome	NN
cord-322166-ajolu2rh	30	13	:	:	:
cord-322166-ajolu2rh	30	14	the	the	DT
cord-322166-ajolu2rh	30	15	receptor	receptor	NN
cord-322166-ajolu2rh	30	16	-	-	HYPH
cord-322166-ajolu2rh	30	17	binding	bind	VBG
cord-322166-ajolu2rh	30	18	protein	protein	NN
cord-322166-ajolu2rh	30	19	hemagglutinin	hemagglutinin	NN
cord-322166-ajolu2rh	30	20	(	(	-LRB-
cord-322166-ajolu2rh	30	21	HA	HA	NNP
cord-322166-ajolu2rh	30	22	)	)	-RRB-
cord-322166-ajolu2rh	30	23	,	,	,
cord-322166-ajolu2rh	30	24	neuraminidase	neuraminidase	FW
cord-322166-ajolu2rh	30	25	(	(	-LRB-
cord-322166-ajolu2rh	30	26	NA	NA	NNP
cord-322166-ajolu2rh	30	27	)	)	-RRB-
cord-322166-ajolu2rh	30	28	,	,	,
cord-322166-ajolu2rh	30	29	nucleoprotein	nucleoprotein	NNP
cord-322166-ajolu2rh	30	30	(	(	-LRB-
cord-322166-ajolu2rh	30	31	NP	NP	NNP
cord-322166-ajolu2rh	30	32	)	)	-RRB-
cord-322166-ajolu2rh	30	33	,	,	,
cord-322166-ajolu2rh	30	34	non	non	JJ
cord-322166-ajolu2rh	30	35	-	-	JJ
cord-322166-ajolu2rh	30	36	structural	structural	JJ
cord-322166-ajolu2rh	30	37	protein	protein	NN
cord-322166-ajolu2rh	30	38	1	1	CD
cord-322166-ajolu2rh	30	39	(	(	-LRB-
cord-322166-ajolu2rh	30	40	NS1	ns1	CD
cord-322166-ajolu2rh	30	41	)	)	-RRB-
cord-322166-ajolu2rh	30	42	,	,	,
cord-322166-ajolu2rh	30	43	nuclear	nuclear	JJ
cord-322166-ajolu2rh	30	44	export	export	NN
cord-322166-ajolu2rh	30	45	protein	protein	NN
cord-322166-ajolu2rh	30	46	(	(	-LRB-
cord-322166-ajolu2rh	30	47	NEP	NEP	NNP
cord-322166-ajolu2rh	30	48	,	,	,
cord-322166-ajolu2rh	30	49	also	also	RB
cord-322166-ajolu2rh	30	50	called	call	VBN
cord-322166-ajolu2rh	30	51	NS2	NS2	NNP
cord-322166-ajolu2rh	30	52	)	)	-RRB-
cord-322166-ajolu2rh	30	53	,	,	,
cord-322166-ajolu2rh	30	54	matrix	matrix	NN
cord-322166-ajolu2rh	30	55	protein	protein	NN
cord-322166-ajolu2rh	30	56	(	(	-LRB-
cord-322166-ajolu2rh	30	57	M1	M1	NNP
cord-322166-ajolu2rh	30	58	)	)	-RRB-
cord-322166-ajolu2rh	30	59	,	,	,
cord-322166-ajolu2rh	30	60	ion	ion	NN
cord-322166-ajolu2rh	30	61	channel	channel	NNP
cord-322166-ajolu2rh	30	62	M2	M2	NNP
cord-322166-ajolu2rh	30	63	,	,	,
cord-322166-ajolu2rh	30	64	the	the	DT
cord-322166-ajolu2rh	30	65	components	component	NNS
cord-322166-ajolu2rh	30	66	of	of	IN
cord-322166-ajolu2rh	30	67	the	the	DT
cord-322166-ajolu2rh	30	68	RNA	RNA	NNP
cord-322166-ajolu2rh	30	69	-	-	HYPH
cord-322166-ajolu2rh	30	70	dependent	dependent	JJ
cord-322166-ajolu2rh	30	71	RNA	RNA	NNP
cord-322166-ajolu2rh	30	72	polymerase	polymerase	NN
cord-322166-ajolu2rh	30	73	complex	complex	NN
cord-322166-ajolu2rh	30	74	(	(	-LRB-
cord-322166-ajolu2rh	30	75	PB1	pb1	NN
cord-322166-ajolu2rh	30	76	,	,	,
cord-322166-ajolu2rh	30	77	PB2	PB2	NNP
cord-322166-ajolu2rh	30	78	,	,	,
cord-322166-ajolu2rh	30	79	and	and	CC
cord-322166-ajolu2rh	30	80	PA	PA	NNP
cord-322166-ajolu2rh	30	81	)	)	-RRB-
cord-322166-ajolu2rh	30	82	,	,	,
cord-322166-ajolu2rh	30	83	and	and	CC
cord-322166-ajolu2rh	30	84	the	the	DT
cord-322166-ajolu2rh	30	85	newly	newly	RB
cord-322166-ajolu2rh	30	86	identified	identify	VBN
cord-322166-ajolu2rh	30	87	N40	N40	NNP
cord-322166-ajolu2rh	30	88	protein	protein	NN
cord-322166-ajolu2rh	30	89	.	.	.
cord-322166-ajolu2rh	31	1	In	in	IN
cord-322166-ajolu2rh	31	2	addition	addition	NN
cord-322166-ajolu2rh	31	3	,	,	,
cord-322166-ajolu2rh	31	4	some	some	DT
cord-322166-ajolu2rh	31	5	viruses	virus	NNS
cord-322166-ajolu2rh	31	6	express	express	VBP
cord-322166-ajolu2rh	31	7	the	the	DT
cord-322166-ajolu2rh	31	8	pro	pro	JJ
cord-322166-ajolu2rh	31	9	-	-	JJ
cord-322166-ajolu2rh	31	10	apoptotic	apoptotic	JJ
cord-322166-ajolu2rh	31	11	protein	protein	NN
cord-322166-ajolu2rh	31	12	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	31	13	.	.	.
cord-322166-ajolu2rh	32	1	(	(	-LRB-
cord-322166-ajolu2rh	32	2	LPAI	LPAI	NNP
cord-322166-ajolu2rh	32	3	)	)	-RRB-
cord-322166-ajolu2rh	33	1	H5N1	H5N1	NNP
cord-322166-ajolu2rh	33	2	virus	virus	NN
cord-322166-ajolu2rh	33	3	isolated	isolate	VBN
cord-322166-ajolu2rh	33	4	from	from	IN
cord-322166-ajolu2rh	33	5	geese	goose	NNS
cord-322166-ajolu2rh	33	6	(	(	-LRB-
cord-322166-ajolu2rh	33	7	Medina	Medina	NNP
cord-322166-ajolu2rh	33	8	R	R	NNP
cord-322166-ajolu2rh	33	9	A	A	NNP
cord-322166-ajolu2rh	33	10	,	,	,
cord-322166-ajolu2rh	33	11	et	et	FW
cord-322166-ajolu2rh	33	12	al	al	NNP
cord-322166-ajolu2rh	33	13	.	.	.
cord-322166-ajolu2rh	34	1	,	,	,
cord-322166-ajolu2rh	34	2	2011	2011	CD
cord-322166-ajolu2rh	34	3	;	;	:
cord-322166-ajolu2rh	34	4	Mukhtar	Mukhtar	NNP
cord-322166-ajolu2rh	34	5	M	M	NNP
cord-322166-ajolu2rh	34	6	M	M	NNP
cord-322166-ajolu2rh	34	7	,	,	,
cord-322166-ajolu2rh	34	8	et	et	NNP
cord-322166-ajolu2rh	34	9	al	al	NNP
cord-322166-ajolu2rh	34	10	.	.	NNP
cord-322166-ajolu2rh	34	11	,	,	,
cord-322166-ajolu2rh	34	12	2007	2007	CD
cord-322166-ajolu2rh	34	13	)	)	-RRB-
cord-322166-ajolu2rh	34	14	.	.	.
cord-322166-ajolu2rh	35	1	In	in	IN
cord-322166-ajolu2rh	35	2	March	March	NNP
cord-322166-ajolu2rh	35	3	1997	1997	CD
cord-322166-ajolu2rh	35	4	,	,	,
cord-322166-ajolu2rh	35	5	the	the	DT
cord-322166-ajolu2rh	35	6	previously	previously	RB
cord-322166-ajolu2rh	35	7	isolated	isolate	VBN
cord-322166-ajolu2rh	35	8	HPAI	HPAI	NNP
cord-322166-ajolu2rh	35	9	H5N1	H5N1	NNP
cord-322166-ajolu2rh	35	10	outbreaks	outbreak	NNS
cord-322166-ajolu2rh	35	11	exploded	explode	VBD
cord-322166-ajolu2rh	35	12	into	into	IN
cord-322166-ajolu2rh	35	13	a	a	DT
cord-322166-ajolu2rh	35	14	massive	massive	JJ
cord-322166-ajolu2rh	35	15	outbreak	outbreak	NN
cord-322166-ajolu2rh	35	16	in	in	IN
cord-322166-ajolu2rh	35	17	chickens	chicken	NNS
cord-322166-ajolu2rh	35	18	in	in	IN
cord-322166-ajolu2rh	35	19	Hong	Hong	NNP
cord-322166-ajolu2rh	35	20	Kong	Kong	NNP
cord-322166-ajolu2rh	35	21	(	(	-LRB-
cord-322166-ajolu2rh	35	22	Centers	Centers	NNPS
cord-322166-ajolu2rh	35	23	for	for	IN
cord-322166-ajolu2rh	35	24	Disease	Disease	NNP
cord-322166-ajolu2rh	35	25	Control	Control	NNP
cord-322166-ajolu2rh	35	26	,	,	,
cord-322166-ajolu2rh	35	27	et	et	NNP
cord-322166-ajolu2rh	35	28	al	al	NNP
cord-322166-ajolu2rh	35	29	.	.	NNP
cord-322166-ajolu2rh	35	30	,	,	,
cord-322166-ajolu2rh	35	31	1997	1997	CD
cord-322166-ajolu2rh	35	32	)	)	-RRB-
cord-322166-ajolu2rh	35	33	.	.	.
cord-322166-ajolu2rh	36	1	In	in	IN
cord-322166-ajolu2rh	36	2	contrast	contrast	NN
cord-322166-ajolu2rh	36	3	to	to	IN
cord-322166-ajolu2rh	36	4	1996	1996	CD
cord-322166-ajolu2rh	36	5	,	,	,
cord-322166-ajolu2rh	36	6	the	the	DT
cord-322166-ajolu2rh	36	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	36	8	outbreak	outbreak	NN
cord-322166-ajolu2rh	36	9	among	among	IN
cord-322166-ajolu2rh	36	10	the	the	DT
cord-322166-ajolu2rh	36	11	Hong	Hong	NNP
cord-322166-ajolu2rh	36	12	Kong	Kong	NNP
cord-322166-ajolu2rh	36	13	poultry	poultry	NN
cord-322166-ajolu2rh	36	14	markets	market	NNS
cord-322166-ajolu2rh	36	15	spread	spread	VBP
cord-322166-ajolu2rh	36	16	to	to	IN
cord-322166-ajolu2rh	36	17	humans	human	NNS
cord-322166-ajolu2rh	36	18	,	,	,
cord-322166-ajolu2rh	36	19	with	with	IN
cord-322166-ajolu2rh	36	20	the	the	DT
cord-322166-ajolu2rh	36	21	isolation	isolation	NN
cord-322166-ajolu2rh	36	22	of	of	IN
cord-322166-ajolu2rh	36	23	an	an	DT
cord-322166-ajolu2rh	36	24	H5N1	H5N1	NNP
cord-322166-ajolu2rh	36	25	influenza	influenza	NN
cord-322166-ajolu2rh	36	26	virus	virus	NN
cord-322166-ajolu2rh	36	27	strain	strain	NN
cord-322166-ajolu2rh	36	28	from	from	IN
cord-322166-ajolu2rh	36	29	a	a	DT
cord-322166-ajolu2rh	36	30	3-year	3-year	CD
cord-322166-ajolu2rh	36	31	-	-	HYPH
cord-322166-ajolu2rh	36	32	old	old	JJ
cord-322166-ajolu2rh	36	33	boy	boy	NN
cord-322166-ajolu2rh	36	34	in	in	IN
cord-322166-ajolu2rh	36	35	Hong	Hong	NNP
cord-322166-ajolu2rh	36	36	Kong	Kong	NNP
cord-322166-ajolu2rh	37	1	(	(	-LRB-
cord-322166-ajolu2rh	37	2	Subbarao	Subbarao	NNP
cord-322166-ajolu2rh	37	3	K	K	NNP
cord-322166-ajolu2rh	37	4	,	,	,
cord-322166-ajolu2rh	37	5	et	et	NNP
cord-322166-ajolu2rh	37	6	al	al	NNP
cord-322166-ajolu2rh	37	7	.	.	NNP
cord-322166-ajolu2rh	37	8	,	,	,
cord-322166-ajolu2rh	37	9	1998	1998	CD
cord-322166-ajolu2rh	37	10	)	)	-RRB-
cord-322166-ajolu2rh	37	11	.	.	.
cord-322166-ajolu2rh	38	1	The	the	DT
cord-322166-ajolu2rh	38	2	patient	patient	NN
cord-322166-ajolu2rh	38	3	died	die	VBD
cord-322166-ajolu2rh	38	4	of	of	IN
cord-322166-ajolu2rh	38	5	severe	severe	JJ
cord-322166-ajolu2rh	38	6	pneumonia	pneumonia	NN
cord-322166-ajolu2rh	38	7	complicated	complicate	VBN
cord-322166-ajolu2rh	38	8	by	by	IN
cord-322166-ajolu2rh	38	9	acute	acute	JJ
cord-322166-ajolu2rh	38	10	respiratory	respiratory	JJ
cord-322166-ajolu2rh	38	11	distress	distress	NN
cord-322166-ajolu2rh	38	12	syndrome	syndrome	NN
cord-322166-ajolu2rh	38	13	and	and	CC
cord-322166-ajolu2rh	38	14	Reye	Reye	NNP
cord-322166-ajolu2rh	38	15	's	's	POS
cord-322166-ajolu2rh	38	16	syndrome	syndrome	NN
cord-322166-ajolu2rh	39	1	(	(	-LRB-
cord-322166-ajolu2rh	39	2	Subbarao	Subbarao	NNP
cord-322166-ajolu2rh	39	3	K	K	NNP
cord-322166-ajolu2rh	39	4	,	,	,
cord-322166-ajolu2rh	39	5	et	et	NNP
cord-322166-ajolu2rh	39	6	al	al	NNP
cord-322166-ajolu2rh	39	7	.	.	NNP
cord-322166-ajolu2rh	39	8	,	,	,
cord-322166-ajolu2rh	39	9	1998	1998	CD
cord-322166-ajolu2rh	39	10	)	)	-RRB-
cord-322166-ajolu2rh	39	11	.	.	.
cord-322166-ajolu2rh	40	1	In	in	IN
cord-322166-ajolu2rh	40	2	1997	1997	CD
cord-322166-ajolu2rh	40	3	,	,	,
cord-322166-ajolu2rh	40	4	a	a	DT
cord-322166-ajolu2rh	40	5	total	total	NN
cord-322166-ajolu2rh	40	6	of	of	IN
cord-322166-ajolu2rh	40	7	18	18	CD
cord-322166-ajolu2rh	40	8	human	human	JJ
cord-322166-ajolu2rh	40	9	cases	case	NNS
cord-322166-ajolu2rh	40	10	were	be	VBD
cord-322166-ajolu2rh	40	11	reported	report	VBN
cord-322166-ajolu2rh	40	12	,	,	,
cord-322166-ajolu2rh	40	13	and	and	CC
cord-322166-ajolu2rh	40	14	of	of	IN
cord-322166-ajolu2rh	40	15	those	those	DT
cord-322166-ajolu2rh	40	16	,	,	,
cord-322166-ajolu2rh	40	17	6	6	CD
cord-322166-ajolu2rh	40	18	were	be	VBD
cord-322166-ajolu2rh	40	19	fatal	fatal	JJ
cord-322166-ajolu2rh	40	20	.	.	.
cord-322166-ajolu2rh	41	1	In	in	IN
cord-322166-ajolu2rh	41	2	1998	1998	CD
cord-322166-ajolu2rh	41	3	,	,	,
cord-322166-ajolu2rh	41	4	a	a	DT
cord-322166-ajolu2rh	41	5	different	different	JJ
cord-322166-ajolu2rh	41	6	avian	avian	JJ
cord-322166-ajolu2rh	41	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	41	8	strain	strain	NN
cord-322166-ajolu2rh	41	9	emerged	emerge	VBD
cord-322166-ajolu2rh	41	10	(	(	-LRB-
cord-322166-ajolu2rh	41	11	Li	Li	NNP
cord-322166-ajolu2rh	41	12	K	K	NNP
cord-322166-ajolu2rh	41	13	S	S	NNP
cord-322166-ajolu2rh	41	14	,	,	,
cord-322166-ajolu2rh	41	15	et	et	NNP
cord-322166-ajolu2rh	41	16	al	al	NNP
cord-322166-ajolu2rh	41	17	.	.	NNP
cord-322166-ajolu2rh	41	18	,	,	,
cord-322166-ajolu2rh	41	19	2004	2004	CD
cord-322166-ajolu2rh	41	20	;	;	:
cord-322166-ajolu2rh	41	21	Yuen	Yuen	NNP
cord-322166-ajolu2rh	41	22	K	K	NNP
cord-322166-ajolu2rh	41	23	Y	Y	NNP
cord-322166-ajolu2rh	41	24	,	,	,
cord-322166-ajolu2rh	41	25	et	et	NNP
cord-322166-ajolu2rh	41	26	al	al	NNP
cord-322166-ajolu2rh	41	27	.	.	NNP
cord-322166-ajolu2rh	41	28	,	,	,
cord-322166-ajolu2rh	41	29	1998	1998	CD
cord-322166-ajolu2rh	41	30	)	)	-RRB-
cord-322166-ajolu2rh	41	31	.	.	.
cord-322166-ajolu2rh	42	1	After	after	IN
cord-322166-ajolu2rh	42	2	a	a	DT
cord-322166-ajolu2rh	42	3	few	few	JJ
cord-322166-ajolu2rh	42	4	years	year	NNS
cord-322166-ajolu2rh	42	5	'	'	POS
cord-322166-ajolu2rh	42	6	silence	silence	NN
cord-322166-ajolu2rh	42	7	,	,	,
cord-322166-ajolu2rh	42	8	in	in	IN
cord-322166-ajolu2rh	42	9	February	February	NNP
cord-322166-ajolu2rh	42	10	2003	2003	CD
cord-322166-ajolu2rh	42	11	,	,	,
cord-322166-ajolu2rh	42	12	H5N1	H5N1	NNP
cord-322166-ajolu2rh	42	13	infections	infection	NNS
cord-322166-ajolu2rh	42	14	were	be	VBD
cord-322166-ajolu2rh	42	15	once	once	RB
cord-322166-ajolu2rh	42	16	again	again	RB
cord-322166-ajolu2rh	42	17	diagnosed	diagnose	VBN
cord-322166-ajolu2rh	42	18	among	among	IN
cord-322166-ajolu2rh	42	19	humans	human	NNS
cord-322166-ajolu2rh	42	20	(	(	-LRB-
cord-322166-ajolu2rh	42	21	Li	Li	NNP
cord-322166-ajolu2rh	42	22	K	K	NNP
cord-322166-ajolu2rh	42	23	S	S	NNP
cord-322166-ajolu2rh	42	24	,	,	,
cord-322166-ajolu2rh	42	25	et	et	NNP
cord-322166-ajolu2rh	42	26	al	al	NNP
cord-322166-ajolu2rh	42	27	.	.	NNP
cord-322166-ajolu2rh	42	28	,	,	,
cord-322166-ajolu2rh	42	29	2004	2004	CD
cord-322166-ajolu2rh	42	30	)	)	-RRB-
cord-322166-ajolu2rh	42	31	.	.	.
cord-322166-ajolu2rh	43	1	The	the	DT
cord-322166-ajolu2rh	43	2	occurrence	occurrence	NN
cord-322166-ajolu2rh	43	3	of	of	IN
cord-322166-ajolu2rh	43	4	frequent	frequent	JJ
cord-322166-ajolu2rh	43	5	outbreaks	outbreak	NNS
cord-322166-ajolu2rh	43	6	of	of	IN
cord-322166-ajolu2rh	43	7	the	the	DT
cord-322166-ajolu2rh	43	8	HPAI	HPAI	NNP
cord-322166-ajolu2rh	43	9	H5N1	H5N1	NNP
cord-322166-ajolu2rh	43	10	virus	virus	NN
cord-322166-ajolu2rh	43	11	among	among	IN
cord-322166-ajolu2rh	43	12	poultry	poultry	NN
cord-322166-ajolu2rh	43	13	since	since	IN
cord-322166-ajolu2rh	43	14	it	-PRON-	PRP
cord-322166-ajolu2rh	43	15	emerged	emerge	VBD
cord-322166-ajolu2rh	43	16	in	in	IN
cord-322166-ajolu2rh	43	17	1996	1996	CD
cord-322166-ajolu2rh	43	18	is	be	VBZ
cord-322166-ajolu2rh	43	19	a	a	DT
cord-322166-ajolu2rh	43	20	cause	cause	NN
cord-322166-ajolu2rh	43	21	of	of	IN
cord-322166-ajolu2rh	43	22	concern	concern	NN
cord-322166-ajolu2rh	43	23	.	.	.
cord-322166-ajolu2rh	44	1	In	in	IN
cord-322166-ajolu2rh	44	2	May	May	NNP
cord-322166-ajolu2rh	44	3	2005	2005	CD
cord-322166-ajolu2rh	44	4	,	,	,
cord-322166-ajolu2rh	44	5	more	more	JJR
cord-322166-ajolu2rh	44	6	than	than	IN
cord-322166-ajolu2rh	44	7	6,000	6,000	CD
cord-322166-ajolu2rh	44	8	infected	infect	VBN
cord-322166-ajolu2rh	44	9	wild	wild	JJ
cord-322166-ajolu2rh	44	10	birds	bird	NNS
cord-322166-ajolu2rh	44	11	on	on	IN
cord-322166-ajolu2rh	44	12	Lake	Lake	NNP
cord-322166-ajolu2rh	44	13	Qinghai	Qinghai	NNP
cord-322166-ajolu2rh	44	14	in	in	IN
cord-322166-ajolu2rh	44	15	Western	Western	NNP
cord-322166-ajolu2rh	44	16	China	China	NNP
cord-322166-ajolu2rh	44	17	were	be	VBD
cord-322166-ajolu2rh	44	18	infected	infect	VBN
cord-322166-ajolu2rh	44	19	and	and	CC
cord-322166-ajolu2rh	44	20	,	,	,
cord-322166-ajolu2rh	44	21	during	during	IN
cord-322166-ajolu2rh	44	22	their	-PRON-	PRP$
cord-322166-ajolu2rh	44	23	seasonal	seasonal	JJ
cord-322166-ajolu2rh	44	24	migrations	migration	NNS
cord-322166-ajolu2rh	44	25	,	,	,
cord-322166-ajolu2rh	44	26	spread	spread	VBD
cord-322166-ajolu2rh	44	27	the	the	DT
cord-322166-ajolu2rh	44	28	H5N1	H5N1	NNP
cord-322166-ajolu2rh	44	29	virus	virus	NN
cord-322166-ajolu2rh	44	30	westward	westward	RB
cord-322166-ajolu2rh	44	31	to	to	IN
cord-322166-ajolu2rh	44	32	Europe	Europe	NNP
cord-322166-ajolu2rh	44	33	and	and	CC
cord-322166-ajolu2rh	44	34	Africa	Africa	NNP
cord-322166-ajolu2rh	44	35	in	in	IN
cord-322166-ajolu2rh	44	36	the	the	DT
cord-322166-ajolu2rh	44	37	years	year	NNS
cord-322166-ajolu2rh	44	38	following	follow	VBG
cord-322166-ajolu2rh	44	39	(	(	-LRB-
cord-322166-ajolu2rh	44	40	Lei	Lei	NNP
cord-322166-ajolu2rh	44	41	F	F	NNP
cord-322166-ajolu2rh	44	42	,	,	,
cord-322166-ajolu2rh	44	43	et	et	NNP
cord-322166-ajolu2rh	44	44	al	al	NNP
cord-322166-ajolu2rh	44	45	.	.	NNP
cord-322166-ajolu2rh	44	46	,	,	,
cord-322166-ajolu2rh	44	47	2011	2011	CD
cord-322166-ajolu2rh	44	48	;	;	:
cord-322166-ajolu2rh	44	49	Liu	Liu	NNP
cord-322166-ajolu2rh	44	50	J	J	NNP
cord-322166-ajolu2rh	44	51	,	,	,
cord-322166-ajolu2rh	44	52	et	et	NNP
cord-322166-ajolu2rh	44	53	al	al	NNP
cord-322166-ajolu2rh	44	54	.	.	NNP
cord-322166-ajolu2rh	44	55	,	,	,
cord-322166-ajolu2rh	44	56	2005	2005	CD
cord-322166-ajolu2rh	44	57	;	;	:
cord-322166-ajolu2rh	44	58	Peiris	Peiris	NNP
cord-322166-ajolu2rh	44	59	J	J	NNP
cord-322166-ajolu2rh	44	60	S	S	NNP
cord-322166-ajolu2rh	44	61	,	,	,
cord-322166-ajolu2rh	44	62	et	et	NNP
cord-322166-ajolu2rh	44	63	al	al	NNP
cord-322166-ajolu2rh	44	64	.	.	NNP
cord-322166-ajolu2rh	44	65	,	,	,
cord-322166-ajolu2rh	44	66	2007	2007	CD
cord-322166-ajolu2rh	44	67	)	)	-RRB-
cord-322166-ajolu2rh	44	68	.	.	.
cord-322166-ajolu2rh	45	1	A	a	DT
cord-322166-ajolu2rh	45	2	new	new	JJ
cord-322166-ajolu2rh	45	3	H5	h5	NN
cord-322166-ajolu2rh	45	4	sub	sub	NN
cord-322166-ajolu2rh	45	5	-	-	NN
cord-322166-ajolu2rh	45	6	lineage	lineage	NN
cord-322166-ajolu2rh	45	7	,	,	,
cord-322166-ajolu2rh	45	8	which	which	WDT
cord-322166-ajolu2rh	45	9	had	have	VBD
cord-322166-ajolu2rh	45	10	an	an	DT
cord-322166-ajolu2rh	45	11	increased	increase	VBN
cord-322166-ajolu2rh	45	12	binding	binding	NN
cord-322166-ajolu2rh	45	13	affinity	affinity	NN
cord-322166-ajolu2rh	45	14	for	for	IN
cord-322166-ajolu2rh	45	15	human	human	JJ
cord-322166-ajolu2rh	45	16	receptors	receptor	NNS
cord-322166-ajolu2rh	45	17	,	,	,
cord-322166-ajolu2rh	45	18	was	be	VBD
cord-322166-ajolu2rh	45	19	isolated	isolate	VBN
cord-322166-ajolu2rh	45	20	in	in	IN
cord-322166-ajolu2rh	45	21	Egypt	Egypt	NNP
cord-322166-ajolu2rh	45	22	in	in	IN
cord-322166-ajolu2rh	45	23	2008	2008	CD
cord-322166-ajolu2rh	46	1	(	(	-LRB-
cord-322166-ajolu2rh	46	2	Watanabe	Watanabe	NNP
cord-322166-ajolu2rh	46	3	Y	Y	NNP
cord-322166-ajolu2rh	46	4	,	,	,
cord-322166-ajolu2rh	46	5	et	et	NNP
cord-322166-ajolu2rh	46	6	al	al	NNP
cord-322166-ajolu2rh	46	7	.	.	NNP
cord-322166-ajolu2rh	46	8	,	,	,
cord-322166-ajolu2rh	46	9	2012	2012	CD
cord-322166-ajolu2rh	46	10	)	)	-RRB-
cord-322166-ajolu2rh	46	11	.	.	.
cord-322166-ajolu2rh	47	1	Studies	study	NNS
cord-322166-ajolu2rh	47	2	showed	show	VBD
cord-322166-ajolu2rh	47	3	that	that	IN
cord-322166-ajolu2rh	47	4	the	the	DT
cord-322166-ajolu2rh	47	5	dominant	dominant	JJ
cord-322166-ajolu2rh	47	6	haemagglutinin	haemagglutinin	NNP
cord-322166-ajolu2rh	47	7	clade	clade	NN
cord-322166-ajolu2rh	47	8	of	of	IN
cord-322166-ajolu2rh	47	9	the	the	DT
cord-322166-ajolu2rh	47	10	H5N1	H5N1	NNP
cord-322166-ajolu2rh	47	11	virus	virus	NN
cord-322166-ajolu2rh	47	12	has	have	VBZ
cord-322166-ajolu2rh	47	13	changed	change	VBN
cord-322166-ajolu2rh	47	14	from	from	IN
cord-322166-ajolu2rh	47	15	clade	clade	NN
cord-322166-ajolu2rh	47	16	0	0	CD
cord-322166-ajolu2rh	47	17	to	to	TO
cord-322166-ajolu2rh	47	18	clade	clade	VB
cord-322166-ajolu2rh	47	19	2.3	2.3	CD
cord-322166-ajolu2rh	47	20	，	，	,
cord-322166-ajolu2rh	47	21	since	since	IN
cord-322166-ajolu2rh	47	22	it	-PRON-	PRP
cord-322166-ajolu2rh	47	23	emerged	emerge	VBD
cord-322166-ajolu2rh	47	24	in	in	IN
cord-322166-ajolu2rh	47	25	1996	1996	CD
cord-322166-ajolu2rh	47	26	,	,	,
cord-322166-ajolu2rh	47	27	apparently	apparently	RB
cord-322166-ajolu2rh	47	28	as	as	IN
cord-322166-ajolu2rh	47	29	a	a	DT
cord-322166-ajolu2rh	47	30	result	result	NN
cord-322166-ajolu2rh	47	31	of	of	IN
cord-322166-ajolu2rh	47	32	antigenic	antigenic	JJ
cord-322166-ajolu2rh	47	33	shift	shift	NN
cord-322166-ajolu2rh	47	34	(	(	-LRB-
cord-322166-ajolu2rh	47	35	Pfeiffer	Pfeiffer	NNP
cord-322166-ajolu2rh	47	36	D	D	NNP
cord-322166-ajolu2rh	47	37	U	U	NNP
cord-322166-ajolu2rh	47	38	,	,	,
cord-322166-ajolu2rh	47	39	et	et	NNP
cord-322166-ajolu2rh	47	40	al	al	NNP
cord-322166-ajolu2rh	47	41	.	.	NNP
cord-322166-ajolu2rh	47	42	,	,	,
cord-322166-ajolu2rh	47	43	2011	2011	CD
cord-322166-ajolu2rh	47	44	)	)	-RRB-
cord-322166-ajolu2rh	47	45	.	.	.
cord-322166-ajolu2rh	48	1	Although	although	IN
cord-322166-ajolu2rh	48	2	in	in	IN
cord-322166-ajolu2rh	48	3	the	the	DT
cord-322166-ajolu2rh	48	4	H5N1	H5N1	NNP
cord-322166-ajolu2rh	48	5	infections	infection	NNS
cord-322166-ajolu2rh	48	6	that	that	WDT
cord-322166-ajolu2rh	48	7	occurred	occur	VBD
cord-322166-ajolu2rh	48	8	in	in	IN
cord-322166-ajolu2rh	48	9	Egypt	Egypt	NNP
cord-322166-ajolu2rh	48	10	,	,	,
cord-322166-ajolu2rh	48	11	the	the	DT
cord-322166-ajolu2rh	48	12	morbidity	morbidity	NN
cord-322166-ajolu2rh	48	13	was	be	VBD
cord-322166-ajolu2rh	48	14	not	not	RB
cord-322166-ajolu2rh	48	15	as	as	RB
cord-322166-ajolu2rh	48	16	high	high	JJ
cord-322166-ajolu2rh	48	17	as	as	IN
cord-322166-ajolu2rh	48	18	for	for	IN
cord-322166-ajolu2rh	48	19	seasonal	seasonal	JJ
cord-322166-ajolu2rh	48	20	influenza	influenza	NN
cord-322166-ajolu2rh	48	21	strains	strain	NNS
cord-322166-ajolu2rh	48	22	,	,	,
cord-322166-ajolu2rh	48	23	the	the	DT
cord-322166-ajolu2rh	48	24	mortality	mortality	NN
cord-322166-ajolu2rh	48	25	rate	rate	NN
cord-322166-ajolu2rh	48	26	of	of	IN
cord-322166-ajolu2rh	48	27	approximately	approximately	RB
cord-322166-ajolu2rh	48	28	60	60	CD
cord-322166-ajolu2rh	48	29	%	%	NN
cord-322166-ajolu2rh	48	30	was	be	VBD
cord-322166-ajolu2rh	48	31	substantially	substantially	RB
cord-322166-ajolu2rh	48	32	higher	high	JJR
cord-322166-ajolu2rh	48	33	than	than	IN
cord-322166-ajolu2rh	48	34	for	for	IN
cord-322166-ajolu2rh	48	35	seasonal	seasonal	JJ
cord-322166-ajolu2rh	48	36	influenza	influenza	NN
cord-322166-ajolu2rh	48	37	(	(	-LRB-
cord-322166-ajolu2rh	48	38	Peiris	Peiris	NNP
cord-322166-ajolu2rh	48	39	J	J	NNP
cord-322166-ajolu2rh	48	40	S	S	NNP
cord-322166-ajolu2rh	48	41	,	,	,
cord-322166-ajolu2rh	48	42	et	et	NNP
cord-322166-ajolu2rh	48	43	al	al	NNP
cord-322166-ajolu2rh	48	44	.	.	NNP
cord-322166-ajolu2rh	48	45	,	,	,
cord-322166-ajolu2rh	48	46	2010	2010	CD
cord-322166-ajolu2rh	48	47	)	)	-RRB-
cord-322166-ajolu2rh	48	48	.	.	.
cord-322166-ajolu2rh	49	1	As	as	IN
cord-322166-ajolu2rh	49	2	of	of	IN
cord-322166-ajolu2rh	49	3	December	December	NNP
cord-322166-ajolu2rh	49	4	17	17	CD
cord-322166-ajolu2rh	49	5	,	,	,
cord-322166-ajolu2rh	49	6	2012	2012	CD
cord-322166-ajolu2rh	49	7	,	,	,
cord-322166-ajolu2rh	49	8	according	accord	VBG
cord-322166-ajolu2rh	49	9	to	to	IN
cord-322166-ajolu2rh	49	10	the	the	DT
cord-322166-ajolu2rh	49	11	World	World	NNP
cord-322166-ajolu2rh	49	12	Health	Health	NNP
cord-322166-ajolu2rh	49	13	Organization	Organization	NNP
cord-322166-ajolu2rh	49	14	(	(	-LRB-
cord-322166-ajolu2rh	49	15	WHO	who	WP
cord-322166-ajolu2rh	49	16	)	)	-RRB-
cord-322166-ajolu2rh	49	17	,	,	,
cord-322166-ajolu2rh	49	18	610	610	CD
cord-322166-ajolu2rh	49	19	confirmed	confirm	VBD
cord-322166-ajolu2rh	49	20	cases	case	NNS
cord-322166-ajolu2rh	49	21	of	of	IN
cord-322166-ajolu2rh	49	22	human	human	JJ
cord-322166-ajolu2rh	49	23	H5N1	H5N1	NNP
cord-322166-ajolu2rh	49	24	infection	infection	NN
cord-322166-ajolu2rh	49	25	have	have	VBP
cord-322166-ajolu2rh	49	26	been	be	VBN
cord-322166-ajolu2rh	49	27	reported	report	VBN
cord-322166-ajolu2rh	49	28	since	since	IN
cord-322166-ajolu2rh	49	29	2003	2003	CD
cord-322166-ajolu2rh	49	30	.	.	.
cord-322166-ajolu2rh	50	1	These	these	DT
cord-322166-ajolu2rh	50	2	infections	infection	NNS
cord-322166-ajolu2rh	50	3	have	have	VBP
cord-322166-ajolu2rh	50	4	been	be	VBN
cord-322166-ajolu2rh	50	5	reported	report	VBN
cord-322166-ajolu2rh	50	6	from	from	IN
cord-322166-ajolu2rh	50	7	15	15	CD
cord-322166-ajolu2rh	50	8	different	different	JJ
cord-322166-ajolu2rh	50	9	countries	country	NNS
cord-322166-ajolu2rh	50	10	and	and	CC
cord-322166-ajolu2rh	50	11	resulted	result	VBD
cord-322166-ajolu2rh	50	12	in	in	IN
cord-322166-ajolu2rh	50	13	360	360	CD
cord-322166-ajolu2rh	50	14	deaths	death	NNS
cord-322166-ajolu2rh	50	15	.	.	.
cord-322166-ajolu2rh	51	1	These	these	DT
cord-322166-ajolu2rh	51	2	statistics	statistic	NNS
cord-322166-ajolu2rh	51	3	demonstrate	demonstrate	VBP
cord-322166-ajolu2rh	51	4	that	that	IN
cord-322166-ajolu2rh	51	5	a	a	DT
cord-322166-ajolu2rh	51	6	global	global	JJ
cord-322166-ajolu2rh	51	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	51	8	pandemic	pandemic	NN
cord-322166-ajolu2rh	51	9	would	would	MD
cord-322166-ajolu2rh	51	10	have	have	VB
cord-322166-ajolu2rh	51	11	devastating	devastating	JJ
cord-322166-ajolu2rh	51	12	effects	effect	NNS
cord-322166-ajolu2rh	51	13	,	,	,
cord-322166-ajolu2rh	51	14	and	and	CC
cord-322166-ajolu2rh	51	15	that	that	IN
cord-322166-ajolu2rh	51	16	this	this	DT
cord-322166-ajolu2rh	51	17	virus	virus	NN
cord-322166-ajolu2rh	51	18	represents	represent	VBZ
cord-322166-ajolu2rh	51	19	a	a	DT
cord-322166-ajolu2rh	51	20	serious	serious	JJ
cord-322166-ajolu2rh	51	21	public	public	JJ
cord-322166-ajolu2rh	51	22	health	health	NN
cord-322166-ajolu2rh	51	23	threat	threat	NN
cord-322166-ajolu2rh	51	24	.	.	.
cord-322166-ajolu2rh	52	1	Most	Most	JJS
cord-322166-ajolu2rh	52	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	52	3	influenza	influenza	NN
cord-322166-ajolu2rh	52	4	viruses	virus	NNS
cord-322166-ajolu2rh	52	5	were	be	VBD
cord-322166-ajolu2rh	52	6	isolated	isolate	VBN
cord-322166-ajolu2rh	52	7	during	during	IN
cord-322166-ajolu2rh	52	8	the	the	DT
cord-322166-ajolu2rh	52	9	winter	winter	NN
cord-322166-ajolu2rh	52	10	months	month	NNS
cord-322166-ajolu2rh	52	11	(	(	-LRB-
cord-322166-ajolu2rh	52	12	Peiris	Peiris	NNP
cord-322166-ajolu2rh	52	13	J	J	NNP
cord-322166-ajolu2rh	52	14	S	S	NNP
cord-322166-ajolu2rh	52	15	,	,	,
cord-322166-ajolu2rh	52	16	et	et	NNP
cord-322166-ajolu2rh	52	17	al	al	NNP
cord-322166-ajolu2rh	52	18	.	.	NNP
cord-322166-ajolu2rh	52	19	,	,	,
cord-322166-ajolu2rh	52	20	2007	2007	CD
cord-322166-ajolu2rh	52	21	;	;	:
cord-322166-ajolu2rh	52	22	Suarez	Suarez	NNP
cord-322166-ajolu2rh	52	23	D	D	NNP
cord-322166-ajolu2rh	52	24	L	L	NNP
cord-322166-ajolu2rh	52	25	,	,	,
cord-322166-ajolu2rh	52	26	2010	2010	CD
cord-322166-ajolu2rh	52	27	)	)	-RRB-
cord-322166-ajolu2rh	52	28	.	.	.
cord-322166-ajolu2rh	53	1	The	the	DT
cord-322166-ajolu2rh	53	2	natural	natural	JJ
cord-322166-ajolu2rh	53	3	spread	spread	NN
cord-322166-ajolu2rh	53	4	of	of	IN
cord-322166-ajolu2rh	53	5	the	the	DT
cord-322166-ajolu2rh	53	6	H5N1	H5N1	NNP
cord-322166-ajolu2rh	53	7	virus	virus	NN
cord-322166-ajolu2rh	53	8	results	result	VBZ
cord-322166-ajolu2rh	53	9	,	,	,
cord-322166-ajolu2rh	53	10	in	in	IN
cord-322166-ajolu2rh	53	11	part	part	NN
cord-322166-ajolu2rh	53	12	,	,	,
cord-322166-ajolu2rh	53	13	from	from	IN
cord-322166-ajolu2rh	53	14	the	the	DT
cord-322166-ajolu2rh	53	15	migration	migration	NN
cord-322166-ajolu2rh	53	16	of	of	IN
cord-322166-ajolu2rh	53	17	wild	wild	JJ
cord-322166-ajolu2rh	53	18	birds	bird	NNS
cord-322166-ajolu2rh	53	19	,	,	,
cord-322166-ajolu2rh	53	20	especially	especially	RB
cord-322166-ajolu2rh	53	21	long	long	JJ
cord-322166-ajolu2rh	53	22	-	-	HYPH
cord-322166-ajolu2rh	53	23	distance	distance	NN
cord-322166-ajolu2rh	53	24	migratory	migratory	JJ
cord-322166-ajolu2rh	53	25	birds	bird	NNS
cord-322166-ajolu2rh	53	26	(	(	-LRB-
cord-322166-ajolu2rh	53	27	Ndung'u	ndung'u	RB
cord-322166-ajolu2rh	53	28	T	T	NNP
cord-322166-ajolu2rh	53	29	,	,	,
cord-322166-ajolu2rh	53	30	et	et	NNP
cord-322166-ajolu2rh	53	31	al	al	NNP
cord-322166-ajolu2rh	53	32	.	.	NNP
cord-322166-ajolu2rh	53	33	,	,	,
cord-322166-ajolu2rh	53	34	2006	2006	CD
cord-322166-ajolu2rh	53	35	)	)	-RRB-
cord-322166-ajolu2rh	53	36	.	.	.
cord-322166-ajolu2rh	54	1	The	the	DT
cord-322166-ajolu2rh	54	2	risk	risk	NN
cord-322166-ajolu2rh	54	3	of	of	IN
cord-322166-ajolu2rh	54	4	HPAI	HPAI	NNP
cord-322166-ajolu2rh	54	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	54	6	infection	infection	NN
cord-322166-ajolu2rh	54	7	in	in	IN
cord-322166-ajolu2rh	54	8	wild	wild	JJ
cord-322166-ajolu2rh	54	9	birds	bird	NNS
cord-322166-ajolu2rh	54	10	,	,	,
cord-322166-ajolu2rh	54	11	and	and	CC
cord-322166-ajolu2rh	54	12	the	the	DT
cord-322166-ajolu2rh	54	13	risk	risk	NN
cord-322166-ajolu2rh	54	14	of	of	IN
cord-322166-ajolu2rh	54	15	transmission	transmission	NN
cord-322166-ajolu2rh	54	16	between	between	IN
cord-322166-ajolu2rh	54	17	wild	wild	JJ
cord-322166-ajolu2rh	54	18	birds	bird	NNS
cord-322166-ajolu2rh	54	19	and	and	CC
cord-322166-ajolu2rh	54	20	domestic	domestic	JJ
cord-322166-ajolu2rh	54	21	poultry	poultry	NN
cord-322166-ajolu2rh	54	22	may	may	MD
cord-322166-ajolu2rh	54	23	be	be	VB
cord-322166-ajolu2rh	54	24	similar	similar	JJ
cord-322166-ajolu2rh	54	25	at	at	IN
cord-322166-ajolu2rh	54	26	various	various	JJ
cord-322166-ajolu2rh	54	27	times	time	NNS
cord-322166-ajolu2rh	54	28	of	of	IN
cord-322166-ajolu2rh	54	29	the	the	DT
cord-322166-ajolu2rh	54	30	year	year	NN
cord-322166-ajolu2rh	55	1	(	(	-LRB-
cord-322166-ajolu2rh	55	2	Reperant	Reperant	NNP
cord-322166-ajolu2rh	55	3	L	L	NNP
cord-322166-ajolu2rh	55	4	A	A	NNP
cord-322166-ajolu2rh	55	5	,	,	,
cord-322166-ajolu2rh	55	6	et	et	NNP
cord-322166-ajolu2rh	55	7	al	al	NNP
cord-322166-ajolu2rh	55	8	.	.	NNP
cord-322166-ajolu2rh	55	9	,	,	,
cord-322166-ajolu2rh	55	10	2011	2011	CD
cord-322166-ajolu2rh	55	11	)	)	-RRB-
cord-322166-ajolu2rh	55	12	.	.	.
cord-322166-ajolu2rh	56	1	Another	another	DT
cord-322166-ajolu2rh	56	2	major	major	JJ
cord-322166-ajolu2rh	56	3	factor	factor	NN
cord-322166-ajolu2rh	56	4	in	in	IN
cord-322166-ajolu2rh	56	5	transmission	transmission	NN
cord-322166-ajolu2rh	56	6	is	be	VBZ
cord-322166-ajolu2rh	56	7	the	the	DT
cord-322166-ajolu2rh	56	8	local	local	JJ
cord-322166-ajolu2rh	56	9	commercial	commercial	JJ
cord-322166-ajolu2rh	56	10	poultry	poultry	NN
cord-322166-ajolu2rh	56	11	industry	industry	NN
cord-322166-ajolu2rh	56	12	.	.	.
cord-322166-ajolu2rh	57	1	There	there	RB
cord-322166-ajolu2rh	57	2	,	,	,
cord-322166-ajolu2rh	57	3	large	large	JJ
cord-322166-ajolu2rh	57	4	numbers	number	NNS
cord-322166-ajolu2rh	57	5	of	of	IN
cord-322166-ajolu2rh	57	6	infected	infected	JJ
cord-322166-ajolu2rh	57	7	and	and	CC
cord-322166-ajolu2rh	57	8	uninfected	uninfected	JJ
cord-322166-ajolu2rh	57	9	birds	bird	NNS
cord-322166-ajolu2rh	57	10	are	be	VBP
cord-322166-ajolu2rh	57	11	housed	house	VBN
cord-322166-ajolu2rh	57	12	together	together	RB
cord-322166-ajolu2rh	57	13	,	,	,
cord-322166-ajolu2rh	57	14	(	(	-LRB-
cord-322166-ajolu2rh	57	15	Abdelwhab	Abdelwhab	NNP
cord-322166-ajolu2rh	57	16	E	E	NNP
cord-322166-ajolu2rh	57	17	M	M	NNP
cord-322166-ajolu2rh	57	18	,	,	,
cord-322166-ajolu2rh	57	19	et	et	NNP
cord-322166-ajolu2rh	57	20	al	al	NNP
cord-322166-ajolu2rh	57	21	.	.	NNP
cord-322166-ajolu2rh	57	22	,	,	,
cord-322166-ajolu2rh	57	23	2011	2011	CD
cord-322166-ajolu2rh	57	24	;	;	:
cord-322166-ajolu2rh	57	25	Ndung'u	ndung'u	RB
cord-322166-ajolu2rh	57	26	T	T	NNP
cord-322166-ajolu2rh	57	27	,	,	,
cord-322166-ajolu2rh	57	28	et	et	NNP
cord-322166-ajolu2rh	57	29	al	al	NNP
cord-322166-ajolu2rh	57	30	.	.	NNP
cord-322166-ajolu2rh	57	31	,	,	,
cord-322166-ajolu2rh	57	32	2006	2006	CD
cord-322166-ajolu2rh	57	33	)	)	-RRB-
cord-322166-ajolu2rh	57	34	.	.	.
cord-322166-ajolu2rh	58	1	Wider	wide	JJR
cord-322166-ajolu2rh	58	2	spread	spread	NN
cord-322166-ajolu2rh	58	3	of	of	IN
cord-322166-ajolu2rh	58	4	the	the	DT
cord-322166-ajolu2rh	58	5	virus	virus	NN
cord-322166-ajolu2rh	58	6	among	among	IN
cord-322166-ajolu2rh	58	7	birds	bird	NNS
cord-322166-ajolu2rh	58	8	,	,	,
cord-322166-ajolu2rh	58	9	from	from	IN
cord-322166-ajolu2rh	58	10	birds	bird	NNS
cord-322166-ajolu2rh	58	11	to	to	IN
cord-322166-ajolu2rh	58	12	mammals	mammal	NNS
cord-322166-ajolu2rh	58	13	(	(	-LRB-
cord-322166-ajolu2rh	58	14	including	include	VBG
cord-322166-ajolu2rh	58	15	humans	human	NNS
cord-322166-ajolu2rh	58	16	)	)	-RRB-
cord-322166-ajolu2rh	58	17	,	,	,
cord-322166-ajolu2rh	58	18	and	and	CC
cord-322166-ajolu2rh	58	19	subsequent	subsequent	JJ
cord-322166-ajolu2rh	58	20	spread	spread	NN
cord-322166-ajolu2rh	58	21	among	among	IN
cord-322166-ajolu2rh	58	22	humans	human	NNS
cord-322166-ajolu2rh	58	23	requires	require	VBZ
cord-322166-ajolu2rh	58	24	adaptations	adaptation	NNS
cord-322166-ajolu2rh	58	25	that	that	WDT
cord-322166-ajolu2rh	58	26	favor	favor	VBP
cord-322166-ajolu2rh	58	27	virus	virus	NN
cord-322166-ajolu2rh	58	28	transmission	transmission	NN
cord-322166-ajolu2rh	58	29	rates	rate	NNS
cord-322166-ajolu2rh	58	30	(	(	-LRB-
cord-322166-ajolu2rh	58	31	Gutierrez	Gutierrez	NNP
cord-322166-ajolu2rh	58	32	R	R	NNP
cord-322166-ajolu2rh	58	33	A	A	NNP
cord-322166-ajolu2rh	58	34	,	,	,
cord-322166-ajolu2rh	58	35	et	et	NNP
cord-322166-ajolu2rh	58	36	al	al	NNP
cord-322166-ajolu2rh	58	37	.	.	NNP
cord-322166-ajolu2rh	58	38	,	,	,
cord-322166-ajolu2rh	58	39	2011	2011	CD
cord-322166-ajolu2rh	58	40	;	;	:
cord-322166-ajolu2rh	58	41	Vandegrift	Vandegrift	NNP
cord-322166-ajolu2rh	58	42	K	K	NNP
cord-322166-ajolu2rh	58	43	J	J	NNP
cord-322166-ajolu2rh	58	44	,	,	,
cord-322166-ajolu2rh	58	45	et	et	NNP
cord-322166-ajolu2rh	58	46	al	al	NNP
cord-322166-ajolu2rh	58	47	.	.	NNP
cord-322166-ajolu2rh	58	48	,	,	,
cord-322166-ajolu2rh	58	49	2010	2010	CD
cord-322166-ajolu2rh	58	50	)	)	-RRB-
cord-322166-ajolu2rh	58	51	.	.	.
cord-322166-ajolu2rh	59	1	Most	Most	JJS
cord-322166-ajolu2rh	59	2	human	human	JJ
cord-322166-ajolu2rh	59	3	cases	case	NNS
cord-322166-ajolu2rh	59	4	seem	seem	VBP
cord-322166-ajolu2rh	59	5	to	to	TO
cord-322166-ajolu2rh	59	6	be	be	VB
cord-322166-ajolu2rh	59	7	the	the	DT
cord-322166-ajolu2rh	59	8	result	result	NN
cord-322166-ajolu2rh	59	9	of	of	IN
cord-322166-ajolu2rh	59	10	exposure	exposure	NN
cord-322166-ajolu2rh	59	11	to	to	IN
cord-322166-ajolu2rh	59	12	sick	sick	JJ
cord-322166-ajolu2rh	59	13	poultry	poultry	NN
cord-322166-ajolu2rh	59	14	or	or	CC
cord-322166-ajolu2rh	59	15	the	the	DT
cord-322166-ajolu2rh	59	16	butchering	butchering	NN
cord-322166-ajolu2rh	59	17	of	of	IN
cord-322166-ajolu2rh	59	18	birds	bird	NNS
cord-322166-ajolu2rh	59	19	.	.	.
cord-322166-ajolu2rh	60	1	However	however	RB
cord-322166-ajolu2rh	60	2	,	,	,
cord-322166-ajolu2rh	60	3	a	a	DT
cord-322166-ajolu2rh	60	4	number	number	NN
cord-322166-ajolu2rh	60	5	of	of	IN
cord-322166-ajolu2rh	60	6	confirmed	confirm	VBN
cord-322166-ajolu2rh	60	7	human	human	JJ
cord-322166-ajolu2rh	60	8	cases	case	NNS
cord-322166-ajolu2rh	60	9	show	show	VBP
cord-322166-ajolu2rh	60	10	that	that	IN
cord-322166-ajolu2rh	60	11	H5N1	H5N1	NNP
cord-322166-ajolu2rh	60	12	can	can	MD
cord-322166-ajolu2rh	60	13	spread	spread	VB
cord-322166-ajolu2rh	60	14	by	by	IN
cord-322166-ajolu2rh	60	15	close	close	JJ
cord-322166-ajolu2rh	60	16	contact	contact	NN
cord-322166-ajolu2rh	60	17	with	with	IN
cord-322166-ajolu2rh	60	18	an	an	DT
cord-322166-ajolu2rh	60	19	infected	infected	JJ
cord-322166-ajolu2rh	60	20	patient	patient	NN
cord-322166-ajolu2rh	60	21	(	(	-LRB-
cord-322166-ajolu2rh	60	22	e.g.	e.g.	RB
cord-322166-ajolu2rh	60	23	,	,	,
cord-322166-ajolu2rh	60	24	spread	spread	VBN
cord-322166-ajolu2rh	60	25	to	to	IN
cord-322166-ajolu2rh	60	26	caretakers	caretaker	NNS
cord-322166-ajolu2rh	60	27	of	of	IN
cord-322166-ajolu2rh	60	28	an	an	DT
cord-322166-ajolu2rh	60	29	infected	infected	JJ
cord-322166-ajolu2rh	60	30	family	family	NN
cord-322166-ajolu2rh	60	31	member	member	NN
cord-322166-ajolu2rh	60	32	)	)	-RRB-
cord-322166-ajolu2rh	61	1	(	(	-LRB-
cord-322166-ajolu2rh	61	2	Ungchusak	Ungchusak	NNP
cord-322166-ajolu2rh	61	3	K	K	NNP
cord-322166-ajolu2rh	61	4	,	,	,
cord-322166-ajolu2rh	61	5	et	et	NNP
cord-322166-ajolu2rh	61	6	al	al	NNP
cord-322166-ajolu2rh	61	7	.	.	NNP
cord-322166-ajolu2rh	61	8	,	,	,
cord-322166-ajolu2rh	61	9	2005	2005	CD
cord-322166-ajolu2rh	61	10	;	;	:
cord-322166-ajolu2rh	61	11	Van	Van	NNP
cord-322166-ajolu2rh	61	12	Kerkhove	Kerkhove	NNP
cord-322166-ajolu2rh	61	13	M	M	NNP
cord-322166-ajolu2rh	61	14	D	D	NNP
cord-322166-ajolu2rh	61	15	,	,	,
cord-322166-ajolu2rh	61	16	et	et	NNP
cord-322166-ajolu2rh	61	17	al	al	NNP
cord-322166-ajolu2rh	61	18	.	.	NNP
cord-322166-ajolu2rh	61	19	,	,	,
cord-322166-ajolu2rh	61	20	2011	2011	CD
cord-322166-ajolu2rh	61	21	)	)	-RRB-
cord-322166-ajolu2rh	61	22	.	.	.
cord-322166-ajolu2rh	62	1	Although	although	IN
cord-322166-ajolu2rh	62	2	rare	rare	JJ
cord-322166-ajolu2rh	62	3	,	,	,
cord-322166-ajolu2rh	62	4	human	human	JJ
cord-322166-ajolu2rh	62	5	-	-	HYPH
cord-322166-ajolu2rh	62	6	to	to	IN
cord-322166-ajolu2rh	62	7	-	-	HYPH
cord-322166-ajolu2rh	62	8	human	human	JJ
cord-322166-ajolu2rh	62	9	transmission	transmission	NN
cord-322166-ajolu2rh	62	10	of	of	IN
cord-322166-ajolu2rh	62	11	the	the	DT
cord-322166-ajolu2rh	62	12	H5N1	H5N1	NNP
cord-322166-ajolu2rh	62	13	virus	virus	NN
cord-322166-ajolu2rh	62	14	has	have	VBZ
cord-322166-ajolu2rh	62	15	been	be	VBN
cord-322166-ajolu2rh	62	16	found	find	VBN
cord-322166-ajolu2rh	62	17	in	in	IN
cord-322166-ajolu2rh	62	18	several	several	JJ
cord-322166-ajolu2rh	62	19	household	household	NN
cord-322166-ajolu2rh	62	20	groups	group	NNS
cord-322166-ajolu2rh	62	21	in	in	IN
cord-322166-ajolu2rh	62	22	tribal	tribal	JJ
cord-322166-ajolu2rh	62	23	communities	community	NNS
cord-322166-ajolu2rh	63	1	(	(	-LRB-
cord-322166-ajolu2rh	63	2	Van	Van	NNP
cord-322166-ajolu2rh	63	3	Kerkhove	Kerkhove	NNP
cord-322166-ajolu2rh	63	4	M	M	NNP
cord-322166-ajolu2rh	63	5	D	D	NNP
cord-322166-ajolu2rh	63	6	,	,	,
cord-322166-ajolu2rh	63	7	et	et	NNP
cord-322166-ajolu2rh	63	8	al	al	NNP
cord-322166-ajolu2rh	63	9	.	.	NNP
cord-322166-ajolu2rh	63	10	,	,	,
cord-322166-ajolu2rh	63	11	2011	2011	CD
cord-322166-ajolu2rh	63	12	)	)	-RRB-
cord-322166-ajolu2rh	63	13	.	.	.
cord-322166-ajolu2rh	64	1	Consuming	consume	VBG
cord-322166-ajolu2rh	64	2	food	food	NN
cord-322166-ajolu2rh	64	3	products	product	NNS
cord-322166-ajolu2rh	64	4	from	from	IN
cord-322166-ajolu2rh	64	5	infected	infected	JJ
cord-322166-ajolu2rh	64	6	poultry	poultry	NN
cord-322166-ajolu2rh	64	7	is	be	VBZ
cord-322166-ajolu2rh	64	8	not	not	RB
cord-322166-ajolu2rh	64	9	likely	likely	JJ
cord-322166-ajolu2rh	64	10	to	to	TO
cord-322166-ajolu2rh	64	11	cause	cause	VB
cord-322166-ajolu2rh	64	12	a	a	DT
cord-322166-ajolu2rh	64	13	human	human	JJ
cord-322166-ajolu2rh	64	14	infection	infection	NN
cord-322166-ajolu2rh	64	15	,	,	,
cord-322166-ajolu2rh	64	16	but	but	CC
cord-322166-ajolu2rh	64	17	there	there	EX
cord-322166-ajolu2rh	64	18	is	be	VBZ
cord-322166-ajolu2rh	64	19	evidence	evidence	NN
cord-322166-ajolu2rh	64	20	that	that	IN
cord-322166-ajolu2rh	64	21	cats	cat	NNS
cord-322166-ajolu2rh	64	22	have	have	VBP
cord-322166-ajolu2rh	64	23	become	become	VBN
cord-322166-ajolu2rh	64	24	infected	infect	VBN
cord-322166-ajolu2rh	64	25	by	by	IN
cord-322166-ajolu2rh	64	26	eating	eat	VBG
cord-322166-ajolu2rh	64	27	raw	raw	JJ
cord-322166-ajolu2rh	64	28	meat	meat	NN
cord-322166-ajolu2rh	64	29	from	from	IN
cord-322166-ajolu2rh	64	30	infected	infected	JJ
cord-322166-ajolu2rh	64	31	chickens	chicken	NNS
cord-322166-ajolu2rh	64	32	,	,	,
cord-322166-ajolu2rh	64	33	and	and	CC
cord-322166-ajolu2rh	64	34	that	that	IN
cord-322166-ajolu2rh	64	35	cats	cat	NNS
cord-322166-ajolu2rh	64	36	could	could	MD
cord-322166-ajolu2rh	64	37	,	,	,
cord-322166-ajolu2rh	64	38	in	in	IN
cord-322166-ajolu2rh	64	39	turn	turn	NN
cord-322166-ajolu2rh	64	40	,	,	,
cord-322166-ajolu2rh	64	41	transmit	transmit	VB
cord-322166-ajolu2rh	64	42	the	the	DT
cord-322166-ajolu2rh	64	43	virus	virus	NN
cord-322166-ajolu2rh	64	44	to	to	IN
cord-322166-ajolu2rh	64	45	their	-PRON-	PRP$
cord-322166-ajolu2rh	64	46	owners	owner	NNS
cord-322166-ajolu2rh	64	47	or	or	CC
cord-322166-ajolu2rh	64	48	to	to	IN
cord-322166-ajolu2rh	64	49	other	other	JJ
cord-322166-ajolu2rh	64	50	household	household	NN
cord-322166-ajolu2rh	64	51	mammals	mammal	NNS
cord-322166-ajolu2rh	64	52	,	,	,
cord-322166-ajolu2rh	64	53	such	such	JJ
cord-322166-ajolu2rh	64	54	as	as	IN
cord-322166-ajolu2rh	64	55	hamsters	hamster	NNS
cord-322166-ajolu2rh	65	1	(	(	-LRB-
cord-322166-ajolu2rh	65	2	Abdelwhab	Abdelwhab	NNP
cord-322166-ajolu2rh	65	3	E	E	NNP
cord-322166-ajolu2rh	65	4	M	M	NNP
cord-322166-ajolu2rh	65	5	,	,	,
cord-322166-ajolu2rh	65	6	et	et	NNP
cord-322166-ajolu2rh	65	7	al	al	NNP
cord-322166-ajolu2rh	65	8	.	.	NNP
cord-322166-ajolu2rh	65	9	,	,	,
cord-322166-ajolu2rh	65	10	2011	2011	CD
cord-322166-ajolu2rh	65	11	;	;	:
cord-322166-ajolu2rh	65	12	Thiry	Thiry	NNP
cord-322166-ajolu2rh	65	13	E	E	NNP
cord-322166-ajolu2rh	65	14	,	,	,
cord-322166-ajolu2rh	65	15	et	et	NNP
cord-322166-ajolu2rh	65	16	al	al	NNP
cord-322166-ajolu2rh	65	17	.	.	NNP
cord-322166-ajolu2rh	65	18	,	,	,
cord-322166-ajolu2rh	65	19	2007	2007	CD
cord-322166-ajolu2rh	65	20	)	)	-RRB-
cord-322166-ajolu2rh	65	21	.	.	.
cord-322166-ajolu2rh	66	1	Other	other	JJ
cord-322166-ajolu2rh	66	2	studies	study	NNS
cord-322166-ajolu2rh	66	3	performed	perform	VBN
cord-322166-ajolu2rh	66	4	since	since	IN
cord-322166-ajolu2rh	66	5	the	the	DT
cord-322166-ajolu2rh	66	6	emergence	emergence	NN
cord-322166-ajolu2rh	66	7	of	of	IN
cord-322166-ajolu2rh	66	8	HPAI	HPAI	NNP
cord-322166-ajolu2rh	66	9	H5N1	H5N1	NNP
cord-322166-ajolu2rh	66	10	show	show	VBP
cord-322166-ajolu2rh	66	11	that	that	IN
cord-322166-ajolu2rh	66	12	the	the	DT
cord-322166-ajolu2rh	66	13	virus	virus	NN
cord-322166-ajolu2rh	66	14	can	can	MD
cord-322166-ajolu2rh	66	15	be	be	VB
cord-322166-ajolu2rh	66	16	transmitted	transmit	VBN
cord-322166-ajolu2rh	66	17	through	through	IN
cord-322166-ajolu2rh	66	18	contact	contact	NN
cord-322166-ajolu2rh	66	19	with	with	IN
cord-322166-ajolu2rh	66	20	contaminated	contaminated	JJ
cord-322166-ajolu2rh	66	21	water	water	NN
cord-322166-ajolu2rh	66	22	and	and	CC
cord-322166-ajolu2rh	66	23	sewage	sewage	NN
cord-322166-ajolu2rh	66	24	,	,	,
cord-322166-ajolu2rh	66	25	a	a	DT
cord-322166-ajolu2rh	66	26	risk	risk	NN
cord-322166-ajolu2rh	66	27	factor	factor	NN
cord-322166-ajolu2rh	66	28	that	that	WDT
cord-322166-ajolu2rh	66	29	must	must	MD
cord-322166-ajolu2rh	66	30	be	be	VB
cord-322166-ajolu2rh	66	31	guarded	guard	VBN
cord-322166-ajolu2rh	66	32	against	against	IN
cord-322166-ajolu2rh	66	33	(	(	-LRB-
cord-322166-ajolu2rh	66	34	Beigel	Beigel	NNP
cord-322166-ajolu2rh	66	35	J	J	NNP
cord-322166-ajolu2rh	66	36	H	H	NNP
cord-322166-ajolu2rh	66	37	,	,	,
cord-322166-ajolu2rh	66	38	et	et	NNP
cord-322166-ajolu2rh	66	39	al	al	NNP
cord-322166-ajolu2rh	66	40	.	.	NNP
cord-322166-ajolu2rh	66	41	,	,	,
cord-322166-ajolu2rh	66	42	2005	2005	CD
cord-322166-ajolu2rh	66	43	;	;	:
cord-322166-ajolu2rh	66	44	Van	Van	NNP
cord-322166-ajolu2rh	66	45	Kerkhove	Kerkhove	NNP
cord-322166-ajolu2rh	66	46	M	M	NNP
cord-322166-ajolu2rh	66	47	D	D	NNP
cord-322166-ajolu2rh	66	48	,	,	,
cord-322166-ajolu2rh	66	49	et	et	NNP
cord-322166-ajolu2rh	66	50	al	al	NNP
cord-322166-ajolu2rh	66	51	.	.	NNP
cord-322166-ajolu2rh	66	52	,	,	,
cord-322166-ajolu2rh	66	53	2011	2011	CD
cord-322166-ajolu2rh	66	54	)	)	-RRB-
cord-322166-ajolu2rh	66	55	.	.	.
cord-322166-ajolu2rh	67	1	Hence	hence	RB
cord-322166-ajolu2rh	67	2	,	,	,
cord-322166-ajolu2rh	67	3	interactions	interaction	NNS
cord-322166-ajolu2rh	67	4	of	of	IN
cord-322166-ajolu2rh	67	5	current	current	JJ
cord-322166-ajolu2rh	67	6	hosts	host	NNS
cord-322166-ajolu2rh	67	7	and	and	CC
cord-322166-ajolu2rh	67	8	their	-PRON-	PRP$
cord-322166-ajolu2rh	67	9	environment	environment	NN
cord-322166-ajolu2rh	67	10	influence	influence	VBP
cord-322166-ajolu2rh	67	11	the	the	DT
cord-322166-ajolu2rh	67	12	ability	ability	NN
cord-322166-ajolu2rh	67	13	of	of	IN
cord-322166-ajolu2rh	67	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	67	15	influenza	influenza	NN
cord-322166-ajolu2rh	67	16	viruses	virus	NNS
cord-322166-ajolu2rh	67	17	to	to	TO
cord-322166-ajolu2rh	67	18	spread	spread	VB
cord-322166-ajolu2rh	67	19	to	to	IN
cord-322166-ajolu2rh	67	20	new	new	JJ
cord-322166-ajolu2rh	67	21	and	and	CC
cord-322166-ajolu2rh	67	22	different	different	JJ
cord-322166-ajolu2rh	67	23	hosts	host	NNS
cord-322166-ajolu2rh	67	24	(	(	-LRB-
cord-322166-ajolu2rh	67	25	Lowen	Lowen	NNP
cord-322166-ajolu2rh	67	26	A	A	NNP
cord-322166-ajolu2rh	67	27	C	C	NNP
cord-322166-ajolu2rh	67	28	,	,	,
cord-322166-ajolu2rh	67	29	et	et	NNP
cord-322166-ajolu2rh	67	30	al	al	NNP
cord-322166-ajolu2rh	67	31	.	.	NNP
cord-322166-ajolu2rh	67	32	,	,	,
cord-322166-ajolu2rh	67	33	2007	2007	CD
cord-322166-ajolu2rh	67	34	;	;	:
cord-322166-ajolu2rh	67	35	Park	Park	NNP
cord-322166-ajolu2rh	67	36	A	a	DT
cord-322166-ajolu2rh	67	37	W	W	NNP
cord-322166-ajolu2rh	67	38	,	,	,
cord-322166-ajolu2rh	67	39	et	et	NNP
cord-322166-ajolu2rh	67	40	al	al	NNP
cord-322166-ajolu2rh	67	41	.	.	NNP
cord-322166-ajolu2rh	67	42	,	,	,
cord-322166-ajolu2rh	67	43	2007	2007	CD
cord-322166-ajolu2rh	67	44	)	)	-RRB-
cord-322166-ajolu2rh	67	45	.	.	.
cord-322166-ajolu2rh	68	1	Genetic	genetic	JJ
cord-322166-ajolu2rh	68	2	characterization	characterization	NN
cord-322166-ajolu2rh	68	3	of	of	IN
cord-322166-ajolu2rh	68	4	the	the	DT
cord-322166-ajolu2rh	68	5	1997	1997	CD
cord-322166-ajolu2rh	68	6	H5N1	H5N1	NNP
cord-322166-ajolu2rh	68	7	strain	strain	NN
cord-322166-ajolu2rh	68	8	showed	show	VBD
cord-322166-ajolu2rh	68	9	that	that	IN
cord-322166-ajolu2rh	68	10	it	-PRON-	PRP
cord-322166-ajolu2rh	68	11	is	be	VBZ
cord-322166-ajolu2rh	68	12	a	a	DT
cord-322166-ajolu2rh	68	13	multiple	multiple	JJ
cord-322166-ajolu2rh	68	14	reassortant	reassortant	JJ
cord-322166-ajolu2rh	68	15	virus	virus	NN
cord-322166-ajolu2rh	68	16	from	from	IN
cord-322166-ajolu2rh	68	17	different	different	JJ
cord-322166-ajolu2rh	68	18	progenitors	progenitor	NNS
cord-322166-ajolu2rh	68	19	.	.	.
cord-322166-ajolu2rh	69	1	The	the	DT
cord-322166-ajolu2rh	69	2	HA	HA	NNP
cord-322166-ajolu2rh	69	3	gene	gene	NN
cord-322166-ajolu2rh	69	4	of	of	IN
cord-322166-ajolu2rh	69	5	the	the	DT
cord-322166-ajolu2rh	69	6	1997	1997	CD
cord-322166-ajolu2rh	69	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	69	8	strain	strain	NN
cord-322166-ajolu2rh	69	9	is	be	VBZ
cord-322166-ajolu2rh	69	10	derived	derive	VBN
cord-322166-ajolu2rh	69	11	from	from	IN
cord-322166-ajolu2rh	69	12	the	the	DT
cord-322166-ajolu2rh	69	13	A	A	NNP
cord-322166-ajolu2rh	69	14	/	/	SYM
cord-322166-ajolu2rh	69	15	Goose	goose	NN
cord-322166-ajolu2rh	69	16	/	/	SYM
cord-322166-ajolu2rh	69	17	Guangdong/1/96	guangdong/1/96	NN
cord-322166-ajolu2rh	69	18	strain	strain	NN
cord-322166-ajolu2rh	69	19	,	,	,
cord-322166-ajolu2rh	69	20	which	which	WDT
cord-322166-ajolu2rh	69	21	was	be	VBD
cord-322166-ajolu2rh	69	22	found	find	VBN
cord-322166-ajolu2rh	69	23	to	to	TO
cord-322166-ajolu2rh	69	24	have	have	VB
cord-322166-ajolu2rh	69	25	close	close	JJ
cord-322166-ajolu2rh	69	26	genomic	genomic	JJ
cord-322166-ajolu2rh	69	27	relationships	relationship	NNS
cord-322166-ajolu2rh	69	28	with	with	IN
cord-322166-ajolu2rh	69	29	H3N8	H3N8	NNP
cord-322166-ajolu2rh	69	30	and	and	CC
cord-322166-ajolu2rh	69	31	H7N1	H7N1	NNP
cord-322166-ajolu2rh	69	32	strains	strain	NNS
cord-322166-ajolu2rh	69	33	,	,	,
cord-322166-ajolu2rh	69	34	as	as	RB
cord-322166-ajolu2rh	69	35	well	well	RB
cord-322166-ajolu2rh	69	36	as	as	IN
cord-322166-ajolu2rh	69	37	with	with	IN
cord-322166-ajolu2rh	69	38	H5N3	H5N3	NNP
cord-322166-ajolu2rh	69	39	strains	strain	NNS
cord-322166-ajolu2rh	69	40	(	(	-LRB-
cord-322166-ajolu2rh	69	41	Li	Li	NNP
cord-322166-ajolu2rh	69	42	K	K	NNP
cord-322166-ajolu2rh	69	43	S	S	NNP
cord-322166-ajolu2rh	69	44	,	,	,
cord-322166-ajolu2rh	69	45	et	et	NNP
cord-322166-ajolu2rh	69	46	al	al	NNP
cord-322166-ajolu2rh	69	47	.	.	NNP
cord-322166-ajolu2rh	69	48	,	,	,
cord-322166-ajolu2rh	69	49	2004	2004	CD
cord-322166-ajolu2rh	69	50	;	;	:
cord-322166-ajolu2rh	69	51	Mukhtar	Mukhtar	NNP
cord-322166-ajolu2rh	69	52	M	M	NNP
cord-322166-ajolu2rh	69	53	M	M	NNP
cord-322166-ajolu2rh	69	54	,	,	,
cord-322166-ajolu2rh	69	55	et	et	NNP
cord-322166-ajolu2rh	69	56	al	al	NNP
cord-322166-ajolu2rh	69	57	.	.	NNP
cord-322166-ajolu2rh	69	58	,	,	,
cord-322166-ajolu2rh	69	59	2007	2007	CD
cord-322166-ajolu2rh	69	60	)	)	-RRB-
cord-322166-ajolu2rh	69	61	.	.	.
cord-322166-ajolu2rh	70	1	An	an	DT
cord-322166-ajolu2rh	70	2	H6N1	H6N1	NNP
cord-322166-ajolu2rh	70	3	virus	virus	NN
cord-322166-ajolu2rh	70	4	contributed	contribute	VBD
cord-322166-ajolu2rh	70	5	the	the	DT
cord-322166-ajolu2rh	70	6	NA	NA	NNP
cord-322166-ajolu2rh	70	7	and	and	CC
cord-322166-ajolu2rh	70	8	some	some	DT
cord-322166-ajolu2rh	70	9	of	of	IN
cord-322166-ajolu2rh	70	10	the	the	DT
cord-322166-ajolu2rh	70	11	internal	internal	JJ
cord-322166-ajolu2rh	70	12	genes	gene	NNS
cord-322166-ajolu2rh	70	13	of	of	IN
cord-322166-ajolu2rh	70	14	the	the	DT
cord-322166-ajolu2rh	70	15	1997	1997	CD
cord-322166-ajolu2rh	70	16	H5N1	H5N1	NNP
cord-322166-ajolu2rh	70	17	,	,	,
cord-322166-ajolu2rh	70	18	and	and	CC
cord-322166-ajolu2rh	70	19	the	the	DT
cord-322166-ajolu2rh	70	20	H9N2	H9N2	NNP
cord-322166-ajolu2rh	70	21	virus	virus	NN
cord-322166-ajolu2rh	70	22	contributed	contribute	VBD
cord-322166-ajolu2rh	70	23	the	the	DT
cord-322166-ajolu2rh	70	24	remaining	remain	VBG
cord-322166-ajolu2rh	70	25	internal	internal	JJ
cord-322166-ajolu2rh	70	26	genes	gene	NNS
cord-322166-ajolu2rh	70	27	(	(	-LRB-
cord-322166-ajolu2rh	70	28	Cauthen	Cauthen	NNP
cord-322166-ajolu2rh	70	29	A	A	NNP
cord-322166-ajolu2rh	70	30	N	N	NNP
cord-322166-ajolu2rh	70	31	,	,	,
cord-322166-ajolu2rh	70	32	et	et	NNP
cord-322166-ajolu2rh	70	33	al	al	NNP
cord-322166-ajolu2rh	70	34	.	.	NNP
cord-322166-ajolu2rh	70	35	,	,	,
cord-322166-ajolu2rh	70	36	2000	2000	CD
cord-322166-ajolu2rh	70	37	;	;	:
cord-322166-ajolu2rh	70	38	Guan	Guan	NNP
cord-322166-ajolu2rh	70	39	Y	Y	NNP
cord-322166-ajolu2rh	70	40	,	,	,
cord-322166-ajolu2rh	70	41	et	et	NNP
cord-322166-ajolu2rh	70	42	al	al	NNP
cord-322166-ajolu2rh	70	43	.	.	NNP
cord-322166-ajolu2rh	70	44	,	,	,
cord-322166-ajolu2rh	70	45	1999	1999	CD
cord-322166-ajolu2rh	70	46	;	;	:
cord-322166-ajolu2rh	70	47	Hoffmann	Hoffmann	NNP
cord-322166-ajolu2rh	70	48	E	E	NNP
cord-322166-ajolu2rh	70	49	,	,	,
cord-322166-ajolu2rh	70	50	et	et	NNP
cord-322166-ajolu2rh	70	51	al	al	NNP
cord-322166-ajolu2rh	70	52	.	.	NNP
cord-322166-ajolu2rh	70	53	,	,	,
cord-322166-ajolu2rh	70	54	2000	2000	CD
cord-322166-ajolu2rh	70	55	)	)	-RRB-
cord-322166-ajolu2rh	70	56	.	.	.
cord-322166-ajolu2rh	71	1	The	the	DT
cord-322166-ajolu2rh	71	2	HPAI	HPAI	NNP
cord-322166-ajolu2rh	71	3	H5N1	H5N1	NNP
cord-322166-ajolu2rh	71	4	virus	virus	NN
cord-322166-ajolu2rh	71	5	became	become	VBD
cord-322166-ajolu2rh	71	6	lethal	lethal	JJ
cord-322166-ajolu2rh	71	7	in	in	IN
cord-322166-ajolu2rh	71	8	poultry	poultry	NN
cord-322166-ajolu2rh	71	9	,	,	,
cord-322166-ajolu2rh	71	10	mammals	mammal	NNS
cord-322166-ajolu2rh	71	11	,	,	,
cord-322166-ajolu2rh	71	12	and	and	CC
cord-322166-ajolu2rh	71	13	human	human	JJ
cord-322166-ajolu2rh	71	14	beings	being	NNS
cord-322166-ajolu2rh	71	15	soon	soon	RB
cord-322166-ajolu2rh	71	16	after	after	IN
cord-322166-ajolu2rh	71	17	the	the	DT
cord-322166-ajolu2rh	71	18	outbreak	outbreak	NN
cord-322166-ajolu2rh	71	19	among	among	IN
cord-322166-ajolu2rh	71	20	wild	wild	JJ
cord-322166-ajolu2rh	71	21	birds	bird	NNS
cord-322166-ajolu2rh	71	22	.	.	.
cord-322166-ajolu2rh	72	1	Recent	recent	JJ
cord-322166-ajolu2rh	72	2	data	datum	NNS
cord-322166-ajolu2rh	72	3	suggest	suggest	VBP
cord-322166-ajolu2rh	72	4	that	that	IN
cord-322166-ajolu2rh	72	5	there	there	EX
cord-322166-ajolu2rh	72	6	are	be	VBP
cord-322166-ajolu2rh	72	7	more	more	JJR
cord-322166-ajolu2rh	72	8	than	than	IN
cord-322166-ajolu2rh	72	9	15	15	CD
cord-322166-ajolu2rh	72	10	H5N1	H5N1	NNP
cord-322166-ajolu2rh	72	11	genotypes	genotype	NNS
cord-322166-ajolu2rh	72	12	distributed	distribute	VBN
cord-322166-ajolu2rh	72	13	globally	globally	RB
cord-322166-ajolu2rh	72	14	,	,	,
cord-322166-ajolu2rh	72	15	with	with	IN
cord-322166-ajolu2rh	72	16	a	a	DT
cord-322166-ajolu2rh	72	17	newly	newly	RB
cord-322166-ajolu2rh	72	18	emerged	emerge	VBN
cord-322166-ajolu2rh	72	19	genotype	genotype	NN
cord-322166-ajolu2rh	72	20	,	,	,
cord-322166-ajolu2rh	72	21	named	name	VBN
cord-322166-ajolu2rh	72	22	genotype	genotype	NN
cord-322166-ajolu2rh	72	23	P	p	NN
cord-322166-ajolu2rh	72	24	(	(	-LRB-
cord-322166-ajolu2rh	72	25	Watanabe	Watanabe	NNP
cord-322166-ajolu2rh	72	26	Y	Y	NNP
cord-322166-ajolu2rh	72	27	,	,	,
cord-322166-ajolu2rh	72	28	et	et	NNP
cord-322166-ajolu2rh	72	29	al	al	NNP
cord-322166-ajolu2rh	72	30	.	.	NNP
cord-322166-ajolu2rh	72	31	,	,	,
cord-322166-ajolu2rh	72	32	2012	2012	CD
cord-322166-ajolu2rh	72	33	)	)	-RRB-
cord-322166-ajolu2rh	72	34	.	.	.
cord-322166-ajolu2rh	73	1	Among	among	IN
cord-322166-ajolu2rh	73	2	all	all	PDT
cord-322166-ajolu2rh	73	3	the	the	DT
cord-322166-ajolu2rh	73	4	circulating	circulate	VBG
cord-322166-ajolu2rh	73	5	genotypes	genotype	NNS
cord-322166-ajolu2rh	73	6	in	in	IN
cord-322166-ajolu2rh	73	7	China	China	NNP
cord-322166-ajolu2rh	73	8	,	,	,
cord-322166-ajolu2rh	73	9	genotype	genotype	NN
cord-322166-ajolu2rh	73	10	V	v	NN
cord-322166-ajolu2rh	73	11	became	become	VBD
cord-322166-ajolu2rh	73	12	the	the	DT
cord-322166-ajolu2rh	73	13	dominant	dominant	JJ
cord-322166-ajolu2rh	73	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	73	15	representative	representative	NN
cord-322166-ajolu2rh	73	16	in	in	IN
cord-322166-ajolu2rh	73	17	2005	2005	CD
cord-322166-ajolu2rh	73	18	,	,	,
cord-322166-ajolu2rh	73	19	rather	rather	RB
cord-322166-ajolu2rh	73	20	than	than	IN
cord-322166-ajolu2rh	73	21	genotype	genotype	NNP
cord-322166-ajolu2rh	73	22	B	B	NNP
cord-322166-ajolu2rh	73	23	and	and	CC
cord-322166-ajolu2rh	73	24	genotype	genotype	NN
cord-322166-ajolu2rh	73	25	Z	z	NN
cord-322166-ajolu2rh	74	1	(	(	-LRB-
cord-322166-ajolu2rh	74	2	Duan	Duan	NNP
cord-322166-ajolu2rh	74	3	L	L	NNP
cord-322166-ajolu2rh	74	4	,	,	,
cord-322166-ajolu2rh	74	5	et	et	NNP
cord-322166-ajolu2rh	74	6	al	al	NNP
cord-322166-ajolu2rh	74	7	.	.	NNP
cord-322166-ajolu2rh	74	8	,	,	,
cord-322166-ajolu2rh	74	9	2008	2008	CD
cord-322166-ajolu2rh	74	10	)	)	-RRB-
cord-322166-ajolu2rh	74	11	.	.	.
cord-322166-ajolu2rh	75	1	Inchoate	inchoate	JJ
cord-322166-ajolu2rh	75	2	studies	study	NNS
cord-322166-ajolu2rh	75	3	indicate	indicate	VBP
cord-322166-ajolu2rh	75	4	that	that	IN
cord-322166-ajolu2rh	75	5	HA	HA	NNP
cord-322166-ajolu2rh	75	6	is	be	VBZ
cord-322166-ajolu2rh	75	7	the	the	DT
cord-322166-ajolu2rh	75	8	major	major	JJ
cord-322166-ajolu2rh	75	9	protein	protein	NN
cord-322166-ajolu2rh	75	10	involved	involve	VBN
cord-322166-ajolu2rh	75	11	in	in	IN
cord-322166-ajolu2rh	75	12	AIV	AIV	NNP
cord-322166-ajolu2rh	75	13	binding	bind	VBG
cord-322166-ajolu2rh	75	14	to	to	IN
cord-322166-ajolu2rh	75	15	its	-PRON-	PRP$
cord-322166-ajolu2rh	75	16	receptor	receptor	NN
cord-322166-ajolu2rh	75	17	on	on	IN
cord-322166-ajolu2rh	75	18	the	the	DT
cord-322166-ajolu2rh	75	19	cell	cell	NN
cord-322166-ajolu2rh	75	20	surface	surface	NN
cord-322166-ajolu2rh	75	21	(	(	-LRB-
cord-322166-ajolu2rh	75	22	Suksatu	Suksatu	NNP
cord-322166-ajolu2rh	75	23	A	A	NNP
cord-322166-ajolu2rh	75	24	,	,	,
cord-322166-ajolu2rh	75	25	et	et	NNP
cord-322166-ajolu2rh	75	26	al	al	NNP
cord-322166-ajolu2rh	75	27	.	.	NNP
cord-322166-ajolu2rh	75	28	,	,	,
cord-322166-ajolu2rh	75	29	2009	2009	CD
cord-322166-ajolu2rh	75	30	)	)	-RRB-
cord-322166-ajolu2rh	75	31	.	.	.
cord-322166-ajolu2rh	76	1	Six	six	CD
cord-322166-ajolu2rh	76	2	of	of	IN
cord-322166-ajolu2rh	76	3	the	the	DT
cord-322166-ajolu2rh	76	4	16	16	CD
cord-322166-ajolu2rh	76	5	known	know	VBN
cord-322166-ajolu2rh	76	6	influenza	influenza	NN
cord-322166-ajolu2rh	76	7	A	a	DT
cord-322166-ajolu2rh	76	8	HA	HA	NNP
cord-322166-ajolu2rh	76	9	serotypes	serotypes	NN
cord-322166-ajolu2rh	76	10	(	(	-LRB-
cord-322166-ajolu2rh	76	11	H1	h1	NN
cord-322166-ajolu2rh	76	12	,	,	,
cord-322166-ajolu2rh	76	13	H2	H2	NNP
cord-322166-ajolu2rh	76	14	,	,	,
cord-322166-ajolu2rh	76	15	H3	H3	NNP
cord-322166-ajolu2rh	76	16	,	,	,
cord-322166-ajolu2rh	76	17	H5	H5	NNP
cord-322166-ajolu2rh	76	18	,	,	,
cord-322166-ajolu2rh	76	19	H7	H7	NNP
cord-322166-ajolu2rh	76	20	,	,	,
cord-322166-ajolu2rh	76	21	and	and	CC
cord-322166-ajolu2rh	76	22	H9	H9	NNP
cord-322166-ajolu2rh	76	23	)	)	-RRB-
cord-322166-ajolu2rh	76	24	have	have	VBP
cord-322166-ajolu2rh	76	25	been	be	VBN
cord-322166-ajolu2rh	76	26	isolated	isolate	VBN
cord-322166-ajolu2rh	76	27	from	from	IN
cord-322166-ajolu2rh	76	28	humans	human	NNS
cord-322166-ajolu2rh	76	29	.	.	.
cord-322166-ajolu2rh	77	1	It	-PRON-	PRP
cord-322166-ajolu2rh	77	2	is	be	VBZ
cord-322166-ajolu2rh	77	3	widely	widely	RB
cord-322166-ajolu2rh	77	4	accepted	accept	VBN
cord-322166-ajolu2rh	77	5	that	that	IN
cord-322166-ajolu2rh	77	6	α-2,6-linked	α-2,6-linke	VBN
cord-322166-ajolu2rh	77	7	sialic	sialic	JJ
cord-322166-ajolu2rh	77	8	acids	acid	NNS
cord-322166-ajolu2rh	77	9	(	(	-LRB-
cord-322166-ajolu2rh	77	10	α-2,6-SA	α-2,6-sa	NN
cord-322166-ajolu2rh	77	11	)	)	-RRB-
cord-322166-ajolu2rh	77	12	are	be	VBP
cord-322166-ajolu2rh	77	13	the	the	DT
cord-322166-ajolu2rh	77	14	primary	primary	JJ
cord-322166-ajolu2rh	77	15	HA	HA	NNP
cord-322166-ajolu2rh	77	16	receptors	receptor	NNS
cord-322166-ajolu2rh	77	17	in	in	IN
cord-322166-ajolu2rh	77	18	the	the	DT
cord-322166-ajolu2rh	77	19	upper	upper	JJ
cord-322166-ajolu2rh	77	20	respiratory	respiratory	JJ
cord-322166-ajolu2rh	77	21	tract	tract	NN
cord-322166-ajolu2rh	77	22	of	of	IN
cord-322166-ajolu2rh	77	23	humans	human	NNS
cord-322166-ajolu2rh	77	24	.	.	.
cord-322166-ajolu2rh	78	1	In	in	IN
cord-322166-ajolu2rh	78	2	contrast	contrast	NN
cord-322166-ajolu2rh	78	3	,	,	,
cord-322166-ajolu2rh	78	4	α-2,3-linked	α-2,3-linked	JJ
cord-322166-ajolu2rh	78	5	sialic	sialic	JJ
cord-322166-ajolu2rh	78	6	acids	acid	NNS
cord-322166-ajolu2rh	78	7	(	(	-LRB-
cord-322166-ajolu2rh	78	8	α-2,3-SA	α-2,3-sa	NN
cord-322166-ajolu2rh	78	9	)	)	-RRB-
cord-322166-ajolu2rh	78	10	that	that	WDT
cord-322166-ajolu2rh	78	11	can	can	MD
cord-322166-ajolu2rh	78	12	be	be	VB
cord-322166-ajolu2rh	78	13	detected	detect	VBN
cord-322166-ajolu2rh	78	14	in	in	IN
cord-322166-ajolu2rh	78	15	duck	duck	NN
cord-322166-ajolu2rh	78	16	intestinal	intestinal	JJ
cord-322166-ajolu2rh	78	17	epithelium	epithelium	NN
cord-322166-ajolu2rh	78	18	are	be	VBP
cord-322166-ajolu2rh	78	19	abundantly	abundantly	RB
cord-322166-ajolu2rh	78	20	distributed	distribute	VBN
cord-322166-ajolu2rh	78	21	on	on	IN
cord-322166-ajolu2rh	78	22	the	the	DT
cord-322166-ajolu2rh	78	23	cells	cell	NNS
cord-322166-ajolu2rh	78	24	of	of	IN
cord-322166-ajolu2rh	78	25	birds	bird	NNS
cord-322166-ajolu2rh	78	26	(	(	-LRB-
cord-322166-ajolu2rh	78	27	van	van	NNP
cord-322166-ajolu2rh	78	28	Riel	Riel	NNP
cord-322166-ajolu2rh	78	29	D	D	NNP
cord-322166-ajolu2rh	78	30	,	,	,
cord-322166-ajolu2rh	78	31	et	et	NNP
cord-322166-ajolu2rh	78	32	al	al	NNP
cord-322166-ajolu2rh	78	33	.	.	NNP
cord-322166-ajolu2rh	78	34	,	,	,
cord-322166-ajolu2rh	78	35	2007	2007	CD
cord-322166-ajolu2rh	78	36	)	)	-RRB-
cord-322166-ajolu2rh	78	37	.	.	.
cord-322166-ajolu2rh	79	1	Although	although	IN
cord-322166-ajolu2rh	79	2	infection	infection	NN
cord-322166-ajolu2rh	79	3	is	be	VBZ
cord-322166-ajolu2rh	79	4	infrequent	infrequent	JJ
cord-322166-ajolu2rh	79	5	,	,	,
cord-322166-ajolu2rh	79	6	current	current	JJ
cord-322166-ajolu2rh	79	7	research	research	NN
cord-322166-ajolu2rh	79	8	shows	show	VBZ
cord-322166-ajolu2rh	79	9	that	that	IN
cord-322166-ajolu2rh	79	10	H5N1	H5N1	NNP
cord-322166-ajolu2rh	79	11	viruses	virus	NNS
cord-322166-ajolu2rh	79	12	do	do	VBP
cord-322166-ajolu2rh	79	13	infect	infect	VB
cord-322166-ajolu2rh	79	14	humans	human	NNS
cord-322166-ajolu2rh	79	15	.	.	.
cord-322166-ajolu2rh	80	1	Various	various	JJ
cord-322166-ajolu2rh	80	2	studies	study	NNS
cord-322166-ajolu2rh	80	3	have	have	VBP
cord-322166-ajolu2rh	80	4	described	describe	VBN
cord-322166-ajolu2rh	80	5	mechanisms	mechanism	NNS
cord-322166-ajolu2rh	80	6	to	to	TO
cord-322166-ajolu2rh	80	7	account	account	VB
cord-322166-ajolu2rh	80	8	for	for	IN
cord-322166-ajolu2rh	80	9	this	this	DT
cord-322166-ajolu2rh	80	10	phenomenon	phenomenon	NN
cord-322166-ajolu2rh	80	11	.	.	.
cord-322166-ajolu2rh	81	1	Cells	cell	NNS
cord-322166-ajolu2rh	81	2	in	in	IN
cord-322166-ajolu2rh	81	3	the	the	DT
cord-322166-ajolu2rh	81	4	lower	low	JJR
cord-322166-ajolu2rh	81	5	respiratory	respiratory	JJ
cord-322166-ajolu2rh	81	6	tract	tract	NN
cord-322166-ajolu2rh	81	7	of	of	IN
cord-322166-ajolu2rh	81	8	humans	human	NNS
cord-322166-ajolu2rh	81	9	,	,	,
cord-322166-ajolu2rh	81	10	such	such	JJ
cord-322166-ajolu2rh	81	11	as	as	IN
cord-322166-ajolu2rh	81	12	type	type	NN
cord-322166-ajolu2rh	81	13	II	II	NNP
cord-322166-ajolu2rh	81	14	pneumocytes	pneumocyte	NNS
cord-322166-ajolu2rh	81	15	,	,	,
cord-322166-ajolu2rh	81	16	alveolar	alveolar	NN
cord-322166-ajolu2rh	81	17	macrophages	macrophage	NNS
cord-322166-ajolu2rh	81	18	and	and	CC
cord-322166-ajolu2rh	81	19	the	the	DT
cord-322166-ajolu2rh	81	20	non	non	JJ
cord-322166-ajolu2rh	81	21	-	-	JJ
cord-322166-ajolu2rh	81	22	ciliated	ciliated	JJ
cord-322166-ajolu2rh	81	23	cuboidal	cuboidal	JJ
cord-322166-ajolu2rh	81	24	epithelial	epithelial	JJ
cord-322166-ajolu2rh	81	25	cells	cell	NNS
cord-322166-ajolu2rh	81	26	of	of	IN
cord-322166-ajolu2rh	81	27	terminal	terminal	JJ
cord-322166-ajolu2rh	81	28	bronchioles	bronchiole	NNS
cord-322166-ajolu2rh	81	29	express	express	VBP
cord-322166-ajolu2rh	81	30	α-2,3-SA	α-2,3-SA	NNP
cord-322166-ajolu2rh	81	31	moieties	moiety	NNS
cord-322166-ajolu2rh	81	32	(	(	-LRB-
cord-322166-ajolu2rh	81	33	Nicholls	Nicholls	NNP
cord-322166-ajolu2rh	81	34	J	J	NNP
cord-322166-ajolu2rh	81	35	M	M	NNP
cord-322166-ajolu2rh	81	36	,	,	,
cord-322166-ajolu2rh	81	37	et	et	NNP
cord-322166-ajolu2rh	81	38	al	al	NNP
cord-322166-ajolu2rh	81	39	.	.	NNP
cord-322166-ajolu2rh	81	40	,	,	,
cord-322166-ajolu2rh	81	41	2007	2007	CD
cord-322166-ajolu2rh	81	42	;	;	:
cord-322166-ajolu2rh	81	43	van	van	NNP
cord-322166-ajolu2rh	81	44	Riel	Riel	NNP
cord-322166-ajolu2rh	81	45	D	D	NNP
cord-322166-ajolu2rh	81	46	,	,	,
cord-322166-ajolu2rh	81	47	et	et	NNP
cord-322166-ajolu2rh	81	48	al	al	NNP
cord-322166-ajolu2rh	81	49	.	.	NNP
cord-322166-ajolu2rh	81	50	,	,	,
cord-322166-ajolu2rh	81	51	2006	2006	CD
cord-322166-ajolu2rh	81	52	)	)	-RRB-
cord-322166-ajolu2rh	81	53	.	.	.
cord-322166-ajolu2rh	82	1	Additionally	additionally	RB
cord-322166-ajolu2rh	82	2	,	,	,
cord-322166-ajolu2rh	82	3	amino	amino	NN
cord-322166-ajolu2rh	82	4	acid	acid	NN
cord-322166-ajolu2rh	82	5	mutations	mutation	NNS
cord-322166-ajolu2rh	82	6	in	in	IN
cord-322166-ajolu2rh	82	7	the	the	DT
cord-322166-ajolu2rh	82	8	HA	HA	NNP
cord-322166-ajolu2rh	82	9	receptor	receptor	NN
cord-322166-ajolu2rh	82	10	-	-	HYPH
cord-322166-ajolu2rh	82	11	binding	bind	VBG
cord-322166-ajolu2rh	82	12	site	site	NN
cord-322166-ajolu2rh	82	13	have	have	VBP
cord-322166-ajolu2rh	82	14	been	be	VBN
cord-322166-ajolu2rh	82	15	identified	identify	VBN
cord-322166-ajolu2rh	82	16	that	that	WDT
cord-322166-ajolu2rh	82	17	may	may	MD
cord-322166-ajolu2rh	82	18	change	change	VB
cord-322166-ajolu2rh	82	19	or	or	CC
cord-322166-ajolu2rh	82	20	broaden	broaden	VB
cord-322166-ajolu2rh	82	21	attachment	attachment	NN
cord-322166-ajolu2rh	82	22	behavior	behavior	NN
cord-322166-ajolu2rh	82	23	and	and	CC
cord-322166-ajolu2rh	82	24	alter	alter	VB
cord-322166-ajolu2rh	82	25	the	the	DT
cord-322166-ajolu2rh	82	26	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	82	27	response	response	NN
cord-322166-ajolu2rh	82	28	of	of	IN
cord-322166-ajolu2rh	82	29	the	the	DT
cord-322166-ajolu2rh	82	30	host	host	NN
cord-322166-ajolu2rh	82	31	or	or	CC
cord-322166-ajolu2rh	82	32	the	the	DT
cord-322166-ajolu2rh	82	33	virulence	virulence	NN
cord-322166-ajolu2rh	82	34	of	of	IN
cord-322166-ajolu2rh	82	35	the	the	DT
cord-322166-ajolu2rh	82	36	virus	virus	NN
cord-322166-ajolu2rh	82	37	(	(	-LRB-
cord-322166-ajolu2rh	82	38	Ayora-	Ayora-	NNP
cord-322166-ajolu2rh	82	39	Talavera	Talavera	NNP
cord-322166-ajolu2rh	82	40	G	G	NNP
cord-322166-ajolu2rh	82	41	,	,	,
cord-322166-ajolu2rh	82	42	et	et	NNP
cord-322166-ajolu2rh	82	43	al	al	NNP
cord-322166-ajolu2rh	82	44	.	.	NNP
cord-322166-ajolu2rh	82	45	,	,	,
cord-322166-ajolu2rh	82	46	2009	2009	CD
cord-322166-ajolu2rh	83	1	;	;	:
cord-322166-ajolu2rh	83	2	Gao	Gao	NNP
cord-322166-ajolu2rh	83	3	Y	Y	NNP
cord-322166-ajolu2rh	83	4	,	,	,
cord-322166-ajolu2rh	83	5	et	et	NNP
cord-322166-ajolu2rh	83	6	al	al	NNP
cord-322166-ajolu2rh	83	7	.	.	NNP
cord-322166-ajolu2rh	83	8	,	,	,
cord-322166-ajolu2rh	83	9	2009	2009	CD
cord-322166-ajolu2rh	83	10	;	;	:
cord-322166-ajolu2rh	83	11	Manz	Manz	NNP
cord-322166-ajolu2rh	83	12	B	B	NNP
cord-322166-ajolu2rh	83	13	,	,	,
cord-322166-ajolu2rh	83	14	et	et	NNP
cord-322166-ajolu2rh	83	15	al	al	NNP
cord-322166-ajolu2rh	83	16	.	.	NNP
cord-322166-ajolu2rh	83	17	,	,	,
cord-322166-ajolu2rh	83	18	2010	2010	CD
cord-322166-ajolu2rh	83	19	;	;	:
cord-322166-ajolu2rh	83	20	Ramos	Ramos	NNP
cord-322166-ajolu2rh	83	21	I	I	NNP
cord-322166-ajolu2rh	83	22	,	,	,
cord-322166-ajolu2rh	83	23	et	et	NNP
cord-322166-ajolu2rh	83	24	al	al	NNP
cord-322166-ajolu2rh	83	25	.	.	NNP
cord-322166-ajolu2rh	83	26	,	,	,
cord-322166-ajolu2rh	83	27	2011	2011	CD
cord-322166-ajolu2rh	83	28	;	;	:
cord-322166-ajolu2rh	83	29	Stevens	Stevens	NNP
cord-322166-ajolu2rh	83	30	J	J	NNP
cord-322166-ajolu2rh	83	31	,	,	,
cord-322166-ajolu2rh	83	32	et	et	NNP
cord-322166-ajolu2rh	83	33	al	al	NNP
cord-322166-ajolu2rh	83	34	.	.	.
cord-322166-ajolu2rh	84	1	,	,	,
cord-322166-ajolu2rh	84	2	2006	2006	CD
cord-322166-ajolu2rh	84	3	;	;	:
cord-322166-ajolu2rh	84	4	Suksatu	Suksatu	NNP
cord-322166-ajolu2rh	84	5	A	A	NNP
cord-322166-ajolu2rh	84	6	,	,	,
cord-322166-ajolu2rh	84	7	et	et	NNP
cord-322166-ajolu2rh	84	8	al	al	NNP
cord-322166-ajolu2rh	84	9	.	.	NNP
cord-322166-ajolu2rh	84	10	,	,	,
cord-322166-ajolu2rh	84	11	2009	2009	CD
cord-322166-ajolu2rh	84	12	)	)	-RRB-
cord-322166-ajolu2rh	84	13	.	.	.
cord-322166-ajolu2rh	85	1	For	for	IN
cord-322166-ajolu2rh	85	2	example	example	NN
cord-322166-ajolu2rh	85	3	,	,	,
cord-322166-ajolu2rh	85	4	mutation	mutation	NN
cord-322166-ajolu2rh	85	5	of	of	IN
cord-322166-ajolu2rh	85	6	the	the	DT
cord-322166-ajolu2rh	85	7	G225D	G225D	NNP
cord-322166-ajolu2rh	85	8	and	and	CC
cord-322166-ajolu2rh	85	9	E190D	E190D	NNP
cord-322166-ajolu2rh	85	10	receptors	receptor	NNS
cord-322166-ajolu2rh	85	11	in	in	IN
cord-322166-ajolu2rh	85	12	the	the	DT
cord-322166-ajolu2rh	85	13	H5N1	H5N1	NNP
cord-322166-ajolu2rh	85	14	virus	virus	NN
cord-322166-ajolu2rh	85	15	HA	HA	NNP
cord-322166-ajolu2rh	85	16	protein	protein	NN
cord-322166-ajolu2rh	85	17	greatly	greatly	RB
cord-322166-ajolu2rh	85	18	decreases	decrease	VBZ
cord-322166-ajolu2rh	85	19	its	-PRON-	PRP$
cord-322166-ajolu2rh	85	20	binding	bind	VBG
cord-322166-ajolu2rh	85	21	affinity	affinity	NN
cord-322166-ajolu2rh	85	22	for	for	IN
cord-322166-ajolu2rh	85	23	α-2,3-SA	α-2,3-sa	NN
cord-322166-ajolu2rh	85	24	without	without	IN
cord-322166-ajolu2rh	85	25	changing	change	VBG
cord-322166-ajolu2rh	85	26	its	-PRON-	PRP$
cord-322166-ajolu2rh	85	27	affinity	affinity	NN
cord-322166-ajolu2rh	85	28	for	for	IN
cord-322166-ajolu2rh	85	29	α-2,6-SA	α-2,6-sa	NN
cord-322166-ajolu2rh	85	30	(	(	-LRB-
cord-322166-ajolu2rh	85	31	Stevens	Stevens	NNP
cord-322166-ajolu2rh	85	32	J	J	NNP
cord-322166-ajolu2rh	85	33	,	,	,
cord-322166-ajolu2rh	85	34	et	et	NNP
cord-322166-ajolu2rh	85	35	al	al	NNP
cord-322166-ajolu2rh	85	36	.	.	NNP
cord-322166-ajolu2rh	85	37	,	,	,
cord-322166-ajolu2rh	85	38	2006	2006	CD
cord-322166-ajolu2rh	85	39	)	)	-RRB-
cord-322166-ajolu2rh	85	40	.	.	.
cord-322166-ajolu2rh	86	1	These	these	DT
cord-322166-ajolu2rh	86	2	data	datum	NNS
cord-322166-ajolu2rh	86	3	indicate	indicate	VBP
cord-322166-ajolu2rh	86	4	that	that	IN
cord-322166-ajolu2rh	86	5	changes	change	NNS
cord-322166-ajolu2rh	86	6	in	in	IN
cord-322166-ajolu2rh	86	7	HA	HA	NNP
cord-322166-ajolu2rh	86	8	dictate	dictate	VBP
cord-322166-ajolu2rh	86	9	the	the	DT
cord-322166-ajolu2rh	86	10	receptor	receptor	NN
cord-322166-ajolu2rh	86	11	-	-	HYPH
cord-322166-ajolu2rh	86	12	binding	bind	VBG
cord-322166-ajolu2rh	86	13	specificity	specificity	NN
cord-322166-ajolu2rh	86	14	for	for	IN
cord-322166-ajolu2rh	86	15	H5N1	H5N1	NNP
cord-322166-ajolu2rh	86	16	viruses	virus	NNS
cord-322166-ajolu2rh	86	17	(	(	-LRB-
cord-322166-ajolu2rh	86	18	Medina	Medina	NNP
cord-322166-ajolu2rh	86	19	R	R	NNP
cord-322166-ajolu2rh	86	20	A	A	NNP
cord-322166-ajolu2rh	86	21	,	,	,
cord-322166-ajolu2rh	86	22	et	et	FW
cord-322166-ajolu2rh	86	23	al	al	NNP
cord-322166-ajolu2rh	87	1	.	.	.
cord-322166-ajolu2rh	88	1	,	,	,
cord-322166-ajolu2rh	88	2	2011	2011	CD
cord-322166-ajolu2rh	88	3	;	;	:
cord-322166-ajolu2rh	88	4	Stevens	Stevens	NNP
cord-322166-ajolu2rh	88	5	J	J	NNP
cord-322166-ajolu2rh	88	6	,	,	,
cord-322166-ajolu2rh	88	7	et	et	NNP
cord-322166-ajolu2rh	88	8	al	al	NNP
cord-322166-ajolu2rh	88	9	.	.	NNP
cord-322166-ajolu2rh	88	10	,	,	,
cord-322166-ajolu2rh	88	11	2006	2006	CD
cord-322166-ajolu2rh	88	12	)	)	-RRB-
cord-322166-ajolu2rh	88	13	.	.	.
cord-322166-ajolu2rh	89	1	Further	further	RB
cord-322166-ajolu2rh	89	2	,	,	,
cord-322166-ajolu2rh	89	3	the	the	DT
cord-322166-ajolu2rh	89	4	relative	relative	JJ
cord-322166-ajolu2rh	89	5	expression	expression	NN
cord-322166-ajolu2rh	89	6	of	of	IN
cord-322166-ajolu2rh	89	7	HA	HA	NNP
cord-322166-ajolu2rh	89	8	and	and	CC
cord-322166-ajolu2rh	89	9	NA	NA	NNP
cord-322166-ajolu2rh	89	10	in	in	IN
cord-322166-ajolu2rh	89	11	the	the	DT
cord-322166-ajolu2rh	89	12	virus	virus	NN
cord-322166-ajolu2rh	89	13	envelope	envelope	NN
cord-322166-ajolu2rh	89	14	can	can	MD
cord-322166-ajolu2rh	89	15	be	be	VB
cord-322166-ajolu2rh	89	16	disrupted	disrupt	VBN
cord-322166-ajolu2rh	89	17	by	by	IN
cord-322166-ajolu2rh	89	18	mutations	mutation	NNS
cord-322166-ajolu2rh	89	19	in	in	IN
cord-322166-ajolu2rh	89	20	HA	HA	NNP
cord-322166-ajolu2rh	89	21	,	,	,
cord-322166-ajolu2rh	89	22	which	which	WDT
cord-322166-ajolu2rh	89	23	changes	change	VBZ
cord-322166-ajolu2rh	89	24	the	the	DT
cord-322166-ajolu2rh	89	25	replication	replication	NN
cord-322166-ajolu2rh	89	26	efficiency	efficiency	NN
cord-322166-ajolu2rh	89	27	of	of	IN
cord-322166-ajolu2rh	89	28	the	the	DT
cord-322166-ajolu2rh	89	29	virus	virus	NN
cord-322166-ajolu2rh	89	30	(	(	-LRB-
cord-322166-ajolu2rh	89	31	Chutinimitkul	Chutinimitkul	NNP
cord-322166-ajolu2rh	89	32	S	S	NNP
cord-322166-ajolu2rh	89	33	,	,	,
cord-322166-ajolu2rh	89	34	et	et	NNP
cord-322166-ajolu2rh	89	35	al	al	NNP
cord-322166-ajolu2rh	89	36	.	.	NNP
cord-322166-ajolu2rh	89	37	,	,	,
cord-322166-ajolu2rh	89	38	2010	2010	CD
cord-322166-ajolu2rh	89	39	)	)	-RRB-
cord-322166-ajolu2rh	89	40	.	.	.
cord-322166-ajolu2rh	90	1	Since	since	IN
cord-322166-ajolu2rh	90	2	pigs	pig	NNS
cord-322166-ajolu2rh	90	3	and	and	CC
cord-322166-ajolu2rh	90	4	some	some	DT
cord-322166-ajolu2rh	90	5	birds	bird	NNS
cord-322166-ajolu2rh	90	6	have	have	VBP
cord-322166-ajolu2rh	90	7	both	both	DT
cord-322166-ajolu2rh	90	8	α-2,3-SA	α-2,3-sa	XX
cord-322166-ajolu2rh	90	9	and	and	CC
cord-322166-ajolu2rh	90	10	α-2,6-SA	α-2,6-sa	NN
cord-322166-ajolu2rh	90	11	receptors	receptor	NNS
cord-322166-ajolu2rh	90	12	(	(	-LRB-
cord-322166-ajolu2rh	90	13	and	and	CC
cord-322166-ajolu2rh	90	14	some	some	DT
cord-322166-ajolu2rh	90	15	have	have	VBP
cord-322166-ajolu2rh	90	16	a	a	DT
cord-322166-ajolu2rh	90	17	third	third	JJ
cord-322166-ajolu2rh	90	18	receptor	receptor	NN
cord-322166-ajolu2rh	90	19	)	)	-RRB-
cord-322166-ajolu2rh	90	20	,	,	,
cord-322166-ajolu2rh	90	21	co	co	NN
cord-322166-ajolu2rh	90	22	-	-	NN
cord-322166-ajolu2rh	90	23	infection	infection	NN
cord-322166-ajolu2rh	90	24	of	of	IN
cord-322166-ajolu2rh	90	25	these	these	DT
cord-322166-ajolu2rh	90	26	animals	animal	NNS
cord-322166-ajolu2rh	90	27	could	could	MD
cord-322166-ajolu2rh	90	28	serve	serve	VB
cord-322166-ajolu2rh	90	29	as	as	IN
cord-322166-ajolu2rh	90	30	an	an	DT
cord-322166-ajolu2rh	90	31	incubator	incubator	NN
cord-322166-ajolu2rh	90	32	to	to	TO
cord-322166-ajolu2rh	90	33	generate	generate	VB
cord-322166-ajolu2rh	90	34	novel	novel	JJ
cord-322166-ajolu2rh	90	35	reassortant	reassortant	NN
cord-322166-ajolu2rh	90	36	viruses	virus	NNS
cord-322166-ajolu2rh	90	37	with	with	IN
cord-322166-ajolu2rh	90	38	increased	increase	VBN
cord-322166-ajolu2rh	90	39	ability	ability	NN
cord-322166-ajolu2rh	90	40	to	to	TO
cord-322166-ajolu2rh	90	41	spread	spread	VB
cord-322166-ajolu2rh	90	42	from	from	IN
cord-322166-ajolu2rh	90	43	animals	animal	NNS
cord-322166-ajolu2rh	90	44	to	to	IN
cord-322166-ajolu2rh	90	45	humans	human	NNS
cord-322166-ajolu2rh	90	46	and	and	CC
cord-322166-ajolu2rh	90	47	humans	human	NNS
cord-322166-ajolu2rh	90	48	to	to	IN
cord-322166-ajolu2rh	90	49	humans	human	NNS
cord-322166-ajolu2rh	91	1	(	(	-LRB-
cord-322166-ajolu2rh	91	2	Gambaryan	Gambaryan	NNP
cord-322166-ajolu2rh	91	3	A	A	NNP
cord-322166-ajolu2rh	91	4	S	S	NNP
cord-322166-ajolu2rh	91	5	,	,	,
cord-322166-ajolu2rh	91	6	et	et	NNP
cord-322166-ajolu2rh	91	7	al	al	NNP
cord-322166-ajolu2rh	91	8	.	.	.
cord-322166-ajolu2rh	92	1	,	,	,
cord-322166-ajolu2rh	92	2	2008	2008	CD
cord-322166-ajolu2rh	92	3	;	;	:
cord-322166-ajolu2rh	92	4	Ito	Ito	NNP
cord-322166-ajolu2rh	92	5	T	T	NNP
cord-322166-ajolu2rh	92	6	,	,	,
cord-322166-ajolu2rh	92	7	et	et	NNP
cord-322166-ajolu2rh	92	8	al	al	NNP
cord-322166-ajolu2rh	92	9	.	.	NNP
cord-322166-ajolu2rh	92	10	,	,	,
cord-322166-ajolu2rh	92	11	1998	1998	CD
cord-322166-ajolu2rh	92	12	;	;	:
cord-322166-ajolu2rh	92	13	Kimble	Kimble	NNP
cord-322166-ajolu2rh	92	14	B	B	NNP
cord-322166-ajolu2rh	92	15	,	,	,
cord-322166-ajolu2rh	92	16	et	et	NNP
cord-322166-ajolu2rh	92	17	al	al	NNP
cord-322166-ajolu2rh	92	18	.	.	NNP
cord-322166-ajolu2rh	92	19	,	,	,
cord-322166-ajolu2rh	92	20	2010	2010	CD
cord-322166-ajolu2rh	92	21	;	;	:
cord-322166-ajolu2rh	92	22	Li	Li	NNP
cord-322166-ajolu2rh	92	23	C	C	NNP
cord-322166-ajolu2rh	92	24	,	,	,
cord-322166-ajolu2rh	92	25	et	et	NNP
cord-322166-ajolu2rh	92	26	al	al	NNP
cord-322166-ajolu2rh	92	27	.	.	NNP
cord-322166-ajolu2rh	92	28	,	,	,
cord-322166-ajolu2rh	92	29	2010	2010	CD
cord-322166-ajolu2rh	92	30	;	;	:
cord-322166-ajolu2rh	92	31	Wan	Wan	NNP
cord-322166-ajolu2rh	92	32	H	H	NNP
cord-322166-ajolu2rh	92	33	,	,	,
cord-322166-ajolu2rh	92	34	et	et	NNP
cord-322166-ajolu2rh	92	35	al	al	NNP
cord-322166-ajolu2rh	92	36	.	.	NNP
cord-322166-ajolu2rh	92	37	,	,	,
cord-322166-ajolu2rh	92	38	2006	2006	CD
cord-322166-ajolu2rh	92	39	)	)	-RRB-
cord-322166-ajolu2rh	92	40	.	.	.
cord-322166-ajolu2rh	93	1	The	the	DT
cord-322166-ajolu2rh	93	2	HA	HA	NNP
cord-322166-ajolu2rh	93	3	protein	protein	NN
cord-322166-ajolu2rh	93	4	has	have	VBZ
cord-322166-ajolu2rh	93	5	also	also	RB
cord-322166-ajolu2rh	93	6	been	be	VBN
cord-322166-ajolu2rh	93	7	suspected	suspect	VBN
cord-322166-ajolu2rh	93	8	of	of	IN
cord-322166-ajolu2rh	93	9	inducing	induce	VBG
cord-322166-ajolu2rh	93	10	autophagy	autophagy	NN
cord-322166-ajolu2rh	93	11	of	of	IN
cord-322166-ajolu2rh	93	12	epithelial	epithelial	JJ
cord-322166-ajolu2rh	93	13	lung	lung	NN
cord-322166-ajolu2rh	93	14	cells	cell	NNS
cord-322166-ajolu2rh	93	15	,	,	,
cord-322166-ajolu2rh	93	16	which	which	WDT
cord-322166-ajolu2rh	93	17	would	would	MD
cord-322166-ajolu2rh	93	18	enable	enable	VB
cord-322166-ajolu2rh	93	19	the	the	DT
cord-322166-ajolu2rh	93	20	virus	virus	NN
cord-322166-ajolu2rh	93	21	to	to	TO
cord-322166-ajolu2rh	93	22	spread	spread	VB
cord-322166-ajolu2rh	93	23	to	to	IN
cord-322166-ajolu2rh	93	24	other	other	JJ
cord-322166-ajolu2rh	93	25	tissues	tissue	NNS
cord-322166-ajolu2rh	93	26	and	and	CC
cord-322166-ajolu2rh	93	27	cause	cause	VB
cord-322166-ajolu2rh	93	28	6	6	CD
cord-322166-ajolu2rh	93	29	further	further	JJ
cord-322166-ajolu2rh	93	30	damage	damage	NN
cord-322166-ajolu2rh	94	1	(	(	-LRB-
cord-322166-ajolu2rh	94	2	Manz	Manz	NNP
cord-322166-ajolu2rh	94	3	B	B	NNP
cord-322166-ajolu2rh	94	4	,	,	,
cord-322166-ajolu2rh	94	5	et	et	NNP
cord-322166-ajolu2rh	94	6	al	al	NNP
cord-322166-ajolu2rh	94	7	.	.	NNP
cord-322166-ajolu2rh	94	8	,	,	,
cord-322166-ajolu2rh	94	9	2010	2010	CD
cord-322166-ajolu2rh	94	10	;	;	:
cord-322166-ajolu2rh	94	11	Sun	Sun	NNP
cord-322166-ajolu2rh	94	12	Y	Y	NNP
cord-322166-ajolu2rh	94	13	,	,	,
cord-322166-ajolu2rh	94	14	et	et	NNP
cord-322166-ajolu2rh	94	15	al	al	NNP
cord-322166-ajolu2rh	94	16	.	.	NNP
cord-322166-ajolu2rh	94	17	,	,	,
cord-322166-ajolu2rh	94	18	2012	2012	CD
cord-322166-ajolu2rh	94	19	;	;	:
cord-322166-ajolu2rh	94	20	Tolnay	Tolnay	NNP
cord-322166-ajolu2rh	94	21	A	A	NNP
cord-322166-ajolu2rh	94	22	E	e	NN
cord-322166-ajolu2rh	94	23	,	,	,
cord-322166-ajolu2rh	94	24	et	et	NNP
cord-322166-ajolu2rh	94	25	al	al	NNP
cord-322166-ajolu2rh	94	26	.	.	NNP
cord-322166-ajolu2rh	94	27	,	,	,
cord-322166-ajolu2rh	94	28	2010	2010	CD
cord-322166-ajolu2rh	94	29	)	)	-RRB-
cord-322166-ajolu2rh	94	30	.	.	.
cord-322166-ajolu2rh	95	1	Other	other	JJ
cord-322166-ajolu2rh	95	2	mechanisms	mechanism	NNS
cord-322166-ajolu2rh	95	3	that	that	WDT
cord-322166-ajolu2rh	95	4	could	could	MD
cord-322166-ajolu2rh	95	5	enable	enable	VB
cord-322166-ajolu2rh	95	6	avian	avian	JJ
cord-322166-ajolu2rh	95	7	-	-	HYPH
cord-322166-ajolu2rh	95	8	to	to	IN
cord-322166-ajolu2rh	95	9	-	-	HYPH
cord-322166-ajolu2rh	95	10	human	human	JJ
cord-322166-ajolu2rh	95	11	transmission	transmission	NN
cord-322166-ajolu2rh	95	12	of	of	IN
cord-322166-ajolu2rh	95	13	H5N1	H5N1	NNP
cord-322166-ajolu2rh	95	14	viruses	virus	NNS
cord-322166-ajolu2rh	95	15	include	include	VBP
cord-322166-ajolu2rh	95	16	the	the	DT
cord-322166-ajolu2rh	95	17	existence	existence	NN
cord-322166-ajolu2rh	95	18	of	of	IN
cord-322166-ajolu2rh	95	19	currently	currently	RB
cord-322166-ajolu2rh	95	20	unknown	unknown	JJ
cord-322166-ajolu2rh	95	21	novel	novel	NN
cord-322166-ajolu2rh	95	22	binding	bind	VBG
cord-322166-ajolu2rh	95	23	sites	site	NNS
cord-322166-ajolu2rh	95	24	on	on	IN
cord-322166-ajolu2rh	95	25	HA	HA	NNP
cord-322166-ajolu2rh	95	26	that	that	WDT
cord-322166-ajolu2rh	95	27	recognize	recognize	VBP
cord-322166-ajolu2rh	95	28	the	the	DT
cord-322166-ajolu2rh	95	29	topology	topology	NN
cord-322166-ajolu2rh	95	30	of	of	IN
cord-322166-ajolu2rh	95	31	sialylated	sialylated	JJ
cord-322166-ajolu2rh	95	32	pentasaccharides	pentasaccharide	NNS
cord-322166-ajolu2rh	95	33	found	find	VBD
cord-322166-ajolu2rh	95	34	on	on	IN
cord-322166-ajolu2rh	95	35	human	human	JJ
cord-322166-ajolu2rh	95	36	cells	cell	NNS
cord-322166-ajolu2rh	95	37	(	(	-LRB-
cord-322166-ajolu2rh	95	38	Chutinimitkul	Chutinimitkul	NNP
cord-322166-ajolu2rh	95	39	S	S	NNP
cord-322166-ajolu2rh	95	40	,	,	,
cord-322166-ajolu2rh	95	41	et	et	NNP
cord-322166-ajolu2rh	95	42	al	al	NNP
cord-322166-ajolu2rh	95	43	.	.	NNP
cord-322166-ajolu2rh	95	44	,	,	,
cord-322166-ajolu2rh	95	45	2010	2010	CD
cord-322166-ajolu2rh	95	46	;	;	:
cord-322166-ajolu2rh	95	47	Medina	Medina	NNP
cord-322166-ajolu2rh	95	48	R	R	NNP
cord-322166-ajolu2rh	95	49	A	A	NNP
cord-322166-ajolu2rh	95	50	,	,	,
cord-322166-ajolu2rh	95	51	et	et	NNP
cord-322166-ajolu2rh	95	52	al	al	NNP
cord-322166-ajolu2rh	95	53	.	.	NNP
cord-322166-ajolu2rh	95	54	,	,	,
cord-322166-ajolu2rh	95	55	2011	2011	CD
cord-322166-ajolu2rh	95	56	;	;	:
cord-322166-ajolu2rh	95	57	Nicholls	Nicholls	NNP
cord-322166-ajolu2rh	95	58	J	J	NNP
cord-322166-ajolu2rh	95	59	M	M	NNP
cord-322166-ajolu2rh	95	60	,	,	,
cord-322166-ajolu2rh	95	61	et	et	NNP
cord-322166-ajolu2rh	95	62	al	al	NNP
cord-322166-ajolu2rh	95	63	.	.	NNP
cord-322166-ajolu2rh	95	64	,	,	,
cord-322166-ajolu2rh	95	65	2007	2007	CD
cord-322166-ajolu2rh	95	66	)	)	-RRB-
cord-322166-ajolu2rh	95	67	.	.	.
cord-322166-ajolu2rh	96	1	No	no	DT
cord-322166-ajolu2rh	96	2	single	single	JJ
cord-322166-ajolu2rh	96	3	viral	viral	JJ
cord-322166-ajolu2rh	96	4	protein	protein	NN
cord-322166-ajolu2rh	96	5	by	by	IN
cord-322166-ajolu2rh	96	6	itself	-PRON-	PRP
cord-322166-ajolu2rh	96	7	ensures	ensure	VBZ
cord-322166-ajolu2rh	96	8	successful	successful	JJ
cord-322166-ajolu2rh	96	9	infection	infection	NN
cord-322166-ajolu2rh	96	10	and	and	CC
cord-322166-ajolu2rh	96	11	robust	robust	JJ
cord-322166-ajolu2rh	96	12	replication	replication	NN
cord-322166-ajolu2rh	96	13	within	within	IN
cord-322166-ajolu2rh	96	14	a	a	DT
cord-322166-ajolu2rh	96	15	host	host	NN
cord-322166-ajolu2rh	96	16	;	;	:
cord-322166-ajolu2rh	96	17	instead	instead	RB
cord-322166-ajolu2rh	96	18	,	,	,
cord-322166-ajolu2rh	96	19	the	the	DT
cord-322166-ajolu2rh	96	20	overall	overall	JJ
cord-322166-ajolu2rh	96	21	constellation	constellation	NN
cord-322166-ajolu2rh	96	22	of	of	IN
cord-322166-ajolu2rh	96	23	genes	gene	NNS
cord-322166-ajolu2rh	96	24	reprograms	reprogram	VBZ
cord-322166-ajolu2rh	96	25	host	host	NN
cord-322166-ajolu2rh	96	26	cells	cell	NNS
cord-322166-ajolu2rh	96	27	for	for	IN
cord-322166-ajolu2rh	96	28	efficient	efficient	JJ
cord-322166-ajolu2rh	96	29	propagation	propagation	NN
cord-322166-ajolu2rh	96	30	and	and	CC
cord-322166-ajolu2rh	96	31	spread	spread	NN
cord-322166-ajolu2rh	96	32	.	.	.
cord-322166-ajolu2rh	97	1	HPAI	HPAI	NNP
cord-322166-ajolu2rh	97	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	97	3	is	be	VBZ
cord-322166-ajolu2rh	97	4	no	no	DT
cord-322166-ajolu2rh	97	5	exception	exception	NN
cord-322166-ajolu2rh	97	6	,	,	,
cord-322166-ajolu2rh	97	7	as	as	IN
cord-322166-ajolu2rh	97	8	several	several	JJ
cord-322166-ajolu2rh	97	9	of	of	IN
cord-322166-ajolu2rh	97	10	the	the	DT
cord-322166-ajolu2rh	97	11	viral	viral	JJ
cord-322166-ajolu2rh	97	12	non	non	JJ
cord-322166-ajolu2rh	97	13	-	-	JJ
cord-322166-ajolu2rh	97	14	structural	structural	JJ
cord-322166-ajolu2rh	97	15	genes	gene	NNS
cord-322166-ajolu2rh	97	16	have	have	VBP
cord-322166-ajolu2rh	97	17	been	be	VBN
cord-322166-ajolu2rh	97	18	reported	report	VBN
cord-322166-ajolu2rh	97	19	to	to	TO
cord-322166-ajolu2rh	97	20	be	be	VB
cord-322166-ajolu2rh	97	21	important	important	JJ
cord-322166-ajolu2rh	97	22	for	for	IN
cord-322166-ajolu2rh	97	23	replication	replication	NN
cord-322166-ajolu2rh	97	24	and	and	CC
cord-322166-ajolu2rh	97	25	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	97	26	.	.	.
cord-322166-ajolu2rh	98	1	It	-PRON-	PRP
cord-322166-ajolu2rh	98	2	has	have	VBZ
cord-322166-ajolu2rh	98	3	been	be	VBN
cord-322166-ajolu2rh	98	4	confirmed	confirm	VBN
cord-322166-ajolu2rh	98	5	that	that	IN
cord-322166-ajolu2rh	98	6	the	the	DT
cord-322166-ajolu2rh	98	7	NS	NS	NNP
cord-322166-ajolu2rh	98	8	gene	gene	NN
cord-322166-ajolu2rh	98	9	contributes	contribute	VBZ
cord-322166-ajolu2rh	98	10	to	to	IN
cord-322166-ajolu2rh	98	11	viral	viral	JJ
cord-322166-ajolu2rh	98	12	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	98	13	in	in	IN
cord-322166-ajolu2rh	98	14	cell	cell	NN
cord-322166-ajolu2rh	98	15	cultures	culture	NNS
cord-322166-ajolu2rh	98	16	and	and	CC
cord-322166-ajolu2rh	98	17	animal	animal	NN
cord-322166-ajolu2rh	98	18	models	model	NNS
cord-322166-ajolu2rh	98	19	(	(	-LRB-
cord-322166-ajolu2rh	98	20	Imai	Imai	NNP
cord-322166-ajolu2rh	98	21	H	H	NNP
cord-322166-ajolu2rh	98	22	,	,	,
cord-322166-ajolu2rh	98	23	et	et	NNP
cord-322166-ajolu2rh	98	24	al	al	NNP
cord-322166-ajolu2rh	98	25	.	.	NNP
cord-322166-ajolu2rh	98	26	,	,	,
cord-322166-ajolu2rh	98	27	2010	2010	CD
cord-322166-ajolu2rh	98	28	)	)	-RRB-
cord-322166-ajolu2rh	98	29	.	.	.
cord-322166-ajolu2rh	99	1	The	the	DT
cord-322166-ajolu2rh	99	2	NS1	ns1	NN
cord-322166-ajolu2rh	99	3	protein	protein	NN
cord-322166-ajolu2rh	99	4	inhibits	inhibit	VBZ
cord-322166-ajolu2rh	99	5	nuclear	nuclear	JJ
cord-322166-ajolu2rh	99	6	export	export	NN
cord-322166-ajolu2rh	99	7	of	of	IN
cord-322166-ajolu2rh	99	8	mRNAs	mRNAs	NNPS
cord-322166-ajolu2rh	99	9	to	to	IN
cord-322166-ajolu2rh	99	10	the	the	DT
cord-322166-ajolu2rh	99	11	cytoplasm	cytoplasm	NN
cord-322166-ajolu2rh	99	12	and	and	CC
cord-322166-ajolu2rh	99	13	binds	bind	VBZ
cord-322166-ajolu2rh	99	14	to	to	IN
cord-322166-ajolu2rh	99	15	the	the	DT
cord-322166-ajolu2rh	99	16	cellular	cellular	JJ
cord-322166-ajolu2rh	99	17	protein	protein	NN
cord-322166-ajolu2rh	99	18	phosphatidylinositol-3-kinase	phosphatidylinositol-3-kinase	NNP
cord-322166-ajolu2rh	99	19	(	(	-LRB-
cord-322166-ajolu2rh	99	20	PI3	PI3	NNP
cord-322166-ajolu2rh	99	21	K	K	NNP
cord-322166-ajolu2rh	99	22	)	)	-RRB-
cord-322166-ajolu2rh	100	1	(	(	-LRB-
cord-322166-ajolu2rh	100	2	Hale	Hale	NNP
cord-322166-ajolu2rh	100	3	B	B	NNP
cord-322166-ajolu2rh	100	4	G	G	NNP
cord-322166-ajolu2rh	100	5	,	,	,
cord-322166-ajolu2rh	100	6	et	et	NNP
cord-322166-ajolu2rh	100	7	al	al	NNP
cord-322166-ajolu2rh	100	8	.	.	NNP
cord-322166-ajolu2rh	100	9	,	,	,
cord-322166-ajolu2rh	100	10	2010	2010	CD
cord-322166-ajolu2rh	100	11	;	;	:
cord-322166-ajolu2rh	100	12	Robb	Robb	NNP
cord-322166-ajolu2rh	100	13	N	N	NNP
cord-322166-ajolu2rh	100	14	C	C	NNP
cord-322166-ajolu2rh	100	15	,	,	,
cord-322166-ajolu2rh	100	16	et	et	NNP
cord-322166-ajolu2rh	100	17	al	al	NNP
cord-322166-ajolu2rh	100	18	.	.	NNP
cord-322166-ajolu2rh	100	19	,	,	,
cord-322166-ajolu2rh	100	20	2012	2012	CD
cord-322166-ajolu2rh	100	21	)	)	-RRB-
cord-322166-ajolu2rh	100	22	.	.	.
cord-322166-ajolu2rh	101	1	Avian	avian	JJ
cord-322166-ajolu2rh	101	2	viruses	virus	NNS
cord-322166-ajolu2rh	101	3	that	that	WDT
cord-322166-ajolu2rh	101	4	have	have	VBP
cord-322166-ajolu2rh	101	5	the	the	DT
cord-322166-ajolu2rh	101	6	HPAI	HPAI	NNP
cord-322166-ajolu2rh	101	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	101	8	NS1	ns1	NN
cord-322166-ajolu2rh	101	9	gene	gene	NN
cord-322166-ajolu2rh	101	10	efficiently	efficiently	RB
cord-322166-ajolu2rh	101	11	block	block	VBP
cord-322166-ajolu2rh	101	12	innate	innate	JJ
cord-322166-ajolu2rh	101	13	immune	immune	JJ
cord-322166-ajolu2rh	101	14	responses	response	NNS
cord-322166-ajolu2rh	101	15	,	,	,
cord-322166-ajolu2rh	101	16	including	include	VBG
cord-322166-ajolu2rh	101	17	reduced	reduce	VBN
cord-322166-ajolu2rh	101	18	interferon	interferon	NN
cord-322166-ajolu2rh	101	19	(	(	-LRB-
cord-322166-ajolu2rh	101	20	IFN	IFN	NNP
cord-322166-ajolu2rh	101	21	)	)	-RRB-
cord-322166-ajolu2rh	101	22	and	and	CC
cord-322166-ajolu2rh	101	23	inducible	inducible	JJ
cord-322166-ajolu2rh	101	24	phosphorylation	phosphorylation	NN
cord-322166-ajolu2rh	101	25	of	of	IN
cord-322166-ajolu2rh	101	26	signal	signal	NN
cord-322166-ajolu2rh	101	27	transducer	transducer	NN
cord-322166-ajolu2rh	101	28	and	and	CC
cord-322166-ajolu2rh	101	29	activator	activator	NN
cord-322166-ajolu2rh	101	30	of	of	IN
cord-322166-ajolu2rh	101	31	transcription	transcription	NN
cord-322166-ajolu2rh	101	32	(	(	-LRB-
cord-322166-ajolu2rh	101	33	STAT	stat	NN
cord-322166-ajolu2rh	101	34	)	)	-RRB-
cord-322166-ajolu2rh	101	35	proteins	protein	NNS
cord-322166-ajolu2rh	101	36	(	(	-LRB-
cord-322166-ajolu2rh	101	37	Jia	Jia	NNP
cord-322166-ajolu2rh	101	38	D	D	NNP
cord-322166-ajolu2rh	101	39	,	,	,
cord-322166-ajolu2rh	101	40	et	et	NNP
cord-322166-ajolu2rh	101	41	al	al	NNP
cord-322166-ajolu2rh	101	42	.	.	NNP
cord-322166-ajolu2rh	101	43	,	,	,
cord-322166-ajolu2rh	101	44	2010	2010	CD
cord-322166-ajolu2rh	101	45	;	;	:
cord-322166-ajolu2rh	101	46	Seo	Seo	NNP
cord-322166-ajolu2rh	101	47	S	S	NNP
cord-322166-ajolu2rh	101	48	H	H	NNP
cord-322166-ajolu2rh	101	49	,	,	,
cord-322166-ajolu2rh	101	50	et	et	NNP
cord-322166-ajolu2rh	101	51	al	al	NNP
cord-322166-ajolu2rh	101	52	.	.	NNP
cord-322166-ajolu2rh	101	53	,	,	,
cord-322166-ajolu2rh	101	54	2002	2002	CD
cord-322166-ajolu2rh	101	55	)	)	-RRB-
cord-322166-ajolu2rh	101	56	.	.	.
cord-322166-ajolu2rh	102	1	Disrupted	disrupt	VBN
cord-322166-ajolu2rh	102	2	cytokine	cytokine	NN
cord-322166-ajolu2rh	102	3	and	and	CC
cord-322166-ajolu2rh	102	4	chemokine	chemokine	JJ
cord-322166-ajolu2rh	102	5	expression	expression	NN
cord-322166-ajolu2rh	102	6	,	,	,
cord-322166-ajolu2rh	102	7	especially	especially	RB
cord-322166-ajolu2rh	102	8	IFNs	IFNs	NNP
cord-322166-ajolu2rh	102	9	and	and	CC
cord-322166-ajolu2rh	102	10	TNF	TNF	NNP
cord-322166-ajolu2rh	102	11	,	,	,
cord-322166-ajolu2rh	102	12	and	and	CC
cord-322166-ajolu2rh	102	13	decreased	decrease	VBD
cord-322166-ajolu2rh	102	14	antiviral	antiviral	JJ
cord-322166-ajolu2rh	102	15	activity	activity	NN
cord-322166-ajolu2rh	102	16	of	of	IN
cord-322166-ajolu2rh	102	17	innate	innate	JJ
cord-322166-ajolu2rh	102	18	immune	immune	JJ
cord-322166-ajolu2rh	102	19	response	response	NN
cord-322166-ajolu2rh	102	20	mediators	mediator	NNS
cord-322166-ajolu2rh	102	21	,	,	,
cord-322166-ajolu2rh	102	22	such	such	JJ
cord-322166-ajolu2rh	102	23	as	as	IN
cord-322166-ajolu2rh	102	24	protein	protein	NN
cord-322166-ajolu2rh	102	25	kinase	kinase	NN
cord-322166-ajolu2rh	102	26	resource	resource	NN
cord-322166-ajolu2rh	102	27	and	and	CC
cord-322166-ajolu2rh	102	28	retinoic	retinoic	JJ
cord-322166-ajolu2rh	102	29	acid	acid	NN
cord-322166-ajolu2rh	102	30	-	-	HYPH
cord-322166-ajolu2rh	102	31	inducible	inducible	JJ
cord-322166-ajolu2rh	102	32	gene	gene	NN
cord-322166-ajolu2rh	102	33	product	product	NN
cord-322166-ajolu2rh	102	34	I	-PRON-	PRP
cord-322166-ajolu2rh	103	1	(	(	-LRB-
cord-322166-ajolu2rh	103	2	RIG	rig	NN
cord-322166-ajolu2rh	103	3	-	-	HYPH
cord-322166-ajolu2rh	103	4	I	I	NNP
cord-322166-ajolu2rh	103	5	)	)	-RRB-
cord-322166-ajolu2rh	103	6	,	,	,
cord-322166-ajolu2rh	103	7	directly	directly	RB
cord-322166-ajolu2rh	103	8	lead	lead	VB
cord-322166-ajolu2rh	103	9	to	to	IN
cord-322166-ajolu2rh	103	10	increased	increase	VBN
cord-322166-ajolu2rh	103	11	virulence	virulence	NN
cord-322166-ajolu2rh	103	12	of	of	IN
cord-322166-ajolu2rh	103	13	the	the	DT
cord-322166-ajolu2rh	103	14	virus	virus	NN
cord-322166-ajolu2rh	103	15	(	(	-LRB-
cord-322166-ajolu2rh	103	16	Haye	Haye	NNP
cord-322166-ajolu2rh	103	17	K	K	NNP
cord-322166-ajolu2rh	103	18	,	,	,
cord-322166-ajolu2rh	103	19	et	et	NNP
cord-322166-ajolu2rh	103	20	al	al	NNP
cord-322166-ajolu2rh	103	21	.	.	NNP
cord-322166-ajolu2rh	103	22	,	,	,
cord-322166-ajolu2rh	103	23	2009	2009	CD
cord-322166-ajolu2rh	103	24	;	;	:
cord-322166-ajolu2rh	103	25	Jackson	Jackson	NNP
cord-322166-ajolu2rh	103	26	D	D	NNP
cord-322166-ajolu2rh	103	27	,	,	,
cord-322166-ajolu2rh	103	28	et	et	NNP
cord-322166-ajolu2rh	103	29	al	al	NNP
cord-322166-ajolu2rh	103	30	.	.	NNP
cord-322166-ajolu2rh	103	31	,	,	,
cord-322166-ajolu2rh	103	32	2008	2008	CD
cord-322166-ajolu2rh	103	33	;	;	:
cord-322166-ajolu2rh	103	34	Lipatov	Lipatov	NNP
cord-322166-ajolu2rh	103	35	A	A	NNP
cord-322166-ajolu2rh	103	36	S	S	NNP
cord-322166-ajolu2rh	103	37	,	,	,
cord-322166-ajolu2rh	103	38	et	et	NNP
cord-322166-ajolu2rh	103	39	al	al	NNP
cord-322166-ajolu2rh	103	40	.	.	NNP
cord-322166-ajolu2rh	103	41	,	,	,
cord-322166-ajolu2rh	103	42	2005	2005	CD
cord-322166-ajolu2rh	103	43	;	;	:
cord-322166-ajolu2rh	103	44	Munir	Munir	NNP
cord-322166-ajolu2rh	103	45	M	M	NNP
cord-322166-ajolu2rh	103	46	,	,	,
cord-322166-ajolu2rh	103	47	et	et	NNP
cord-322166-ajolu2rh	103	48	al	al	NNP
cord-322166-ajolu2rh	103	49	.	.	NNP
cord-322166-ajolu2rh	103	50	,	,	,
cord-322166-ajolu2rh	103	51	2011	2011	CD
cord-322166-ajolu2rh	103	52	)	)	-RRB-
cord-322166-ajolu2rh	103	53	.	.	.
cord-322166-ajolu2rh	104	1	Further	further	RB
cord-322166-ajolu2rh	104	2	,	,	,
cord-322166-ajolu2rh	104	3	it	-PRON-	PRP
cord-322166-ajolu2rh	104	4	has	have	VBZ
cord-322166-ajolu2rh	104	5	been	be	VBN
cord-322166-ajolu2rh	104	6	suggested	suggest	VBN
cord-322166-ajolu2rh	104	7	that	that	IN
cord-322166-ajolu2rh	104	8	the	the	DT
cord-322166-ajolu2rh	104	9	PDZ	PDZ	NNP
cord-322166-ajolu2rh	104	10	domain	domain	NN
cord-322166-ajolu2rh	104	11	binding	bind	VBG
cord-322166-ajolu2rh	104	12	motif	motif	NN
cord-322166-ajolu2rh	104	13	,	,	,
cord-322166-ajolu2rh	104	14	comprised	comprise	VBN
cord-322166-ajolu2rh	104	15	of	of	IN
cord-322166-ajolu2rh	104	16	the	the	DT
cord-322166-ajolu2rh	104	17	four	four	CD
cord-322166-ajolu2rh	104	18	C	c	NN
cord-322166-ajolu2rh	104	19	-	-	HYPH
cord-322166-ajolu2rh	104	20	terminal	terminal	NN
cord-322166-ajolu2rh	104	21	residues	residue	NNS
cord-322166-ajolu2rh	104	22	of	of	IN
cord-322166-ajolu2rh	104	23	NS1	ns1	NN
cord-322166-ajolu2rh	104	24	,	,	,
cord-322166-ajolu2rh	104	25	may	may	MD
cord-322166-ajolu2rh	104	26	influence	influence	VB
cord-322166-ajolu2rh	104	27	pathogenicity	pathogenicity	NN
cord-322166-ajolu2rh	104	28	through	through	IN
cord-322166-ajolu2rh	104	29	an	an	DT
cord-322166-ajolu2rh	104	30	IFN	IFN	NNP
cord-322166-ajolu2rh	104	31	-	-	HYPH
cord-322166-ajolu2rh	104	32	independent	independent	JJ
cord-322166-ajolu2rh	104	33	pathway	pathway	NN
cord-322166-ajolu2rh	104	34	(	(	-LRB-
cord-322166-ajolu2rh	104	35	Jackson	Jackson	NNP
cord-322166-ajolu2rh	104	36	D	D	NNP
cord-322166-ajolu2rh	104	37	,	,	,
cord-322166-ajolu2rh	104	38	et	et	NNP
cord-322166-ajolu2rh	104	39	al	al	NNP
cord-322166-ajolu2rh	104	40	.	.	NNP
cord-322166-ajolu2rh	104	41	,	,	,
cord-322166-ajolu2rh	104	42	2008	2008	CD
cord-322166-ajolu2rh	104	43	)	)	-RRB-
cord-322166-ajolu2rh	104	44	.	.	.
cord-322166-ajolu2rh	105	1	Mutations	mutation	NNS
cord-322166-ajolu2rh	105	2	of	of	IN
cord-322166-ajolu2rh	105	3	a	a	DT
cord-322166-ajolu2rh	105	4	single	single	JJ
cord-322166-ajolu2rh	105	5	residue	residue	NN
cord-322166-ajolu2rh	105	6	or	or	CC
cord-322166-ajolu2rh	105	7	short	short	JJ
cord-322166-ajolu2rh	105	8	sequence	sequence	NN
cord-322166-ajolu2rh	105	9	of	of	IN
cord-322166-ajolu2rh	105	10	NS1	NS1	NNS
cord-322166-ajolu2rh	105	11	have	have	VBP
cord-322166-ajolu2rh	105	12	enabled	enable	VBN
cord-322166-ajolu2rh	105	13	the	the	DT
cord-322166-ajolu2rh	105	14	virus	virus	NN
cord-322166-ajolu2rh	105	15	to	to	TO
cord-322166-ajolu2rh	105	16	spread	spread	VB
cord-322166-ajolu2rh	105	17	across	across	IN
cord-322166-ajolu2rh	105	18	species	specie	NNS
cord-322166-ajolu2rh	105	19	with	with	IN
cord-322166-ajolu2rh	105	20	increased	increase	VBN
cord-322166-ajolu2rh	105	21	virulence	virulence	NN
cord-322166-ajolu2rh	105	22	to	to	IN
cord-322166-ajolu2rh	105	23	the	the	DT
cord-322166-ajolu2rh	105	24	host	host	NN
cord-322166-ajolu2rh	105	25	(	(	-LRB-
cord-322166-ajolu2rh	105	26	Jackson	Jackson	NNP
cord-322166-ajolu2rh	105	27	D	D	NNP
cord-322166-ajolu2rh	105	28	,	,	,
cord-322166-ajolu2rh	105	29	et	et	NNP
cord-322166-ajolu2rh	105	30	al	al	NNP
cord-322166-ajolu2rh	105	31	.	.	NNP
cord-322166-ajolu2rh	105	32	,	,	,
cord-322166-ajolu2rh	105	33	2008	2008	CD
cord-322166-ajolu2rh	105	34	;	;	:
cord-322166-ajolu2rh	105	35	Li	Li	NNP
cord-322166-ajolu2rh	105	36	W	W	NNP
cord-322166-ajolu2rh	105	37	,	,	,
cord-322166-ajolu2rh	105	38	et	et	NNP
cord-322166-ajolu2rh	105	39	al	al	NNP
cord-322166-ajolu2rh	105	40	.	.	.
cord-322166-ajolu2rh	106	1	,	,	,
cord-322166-ajolu2rh	106	2	2010	2010	CD
cord-322166-ajolu2rh	106	3	;	;	:
cord-322166-ajolu2rh	106	4	Long	Long	NNP
cord-322166-ajolu2rh	106	5	J	J	NNP
cord-322166-ajolu2rh	106	6	X	X	NNP
cord-322166-ajolu2rh	106	7	,	,	,
cord-322166-ajolu2rh	106	8	et	et	NNP
cord-322166-ajolu2rh	106	9	al	al	NNP
cord-322166-ajolu2rh	106	10	.	.	NNP
cord-322166-ajolu2rh	106	11	,	,	,
cord-322166-ajolu2rh	106	12	2008	2008	CD
cord-322166-ajolu2rh	106	13	;	;	:
cord-322166-ajolu2rh	106	14	Zhu	Zhu	NNP
cord-322166-ajolu2rh	106	15	Q	Q	NNP
cord-322166-ajolu2rh	106	16	,	,	,
cord-322166-ajolu2rh	106	17	et	et	NNP
cord-322166-ajolu2rh	106	18	al	al	NNP
cord-322166-ajolu2rh	106	19	.	.	NNP
cord-322166-ajolu2rh	106	20	,	,	,
cord-322166-ajolu2rh	106	21	2008	2008	CD
cord-322166-ajolu2rh	106	22	)	)	-RRB-
cord-322166-ajolu2rh	106	23	.	.	.
cord-322166-ajolu2rh	107	1	A	a	DT
cord-322166-ajolu2rh	107	2	deletion	deletion	NN
cord-322166-ajolu2rh	107	3	at	at	IN
cord-322166-ajolu2rh	107	4	position	position	NN
cord-322166-ajolu2rh	107	5	80	80	CD
cord-322166-ajolu2rh	107	6	-	-	SYM
cord-322166-ajolu2rh	107	7	84	84	CD
cord-322166-ajolu2rh	107	8	or	or	CC
cord-322166-ajolu2rh	107	9	191	191	CD
cord-322166-ajolu2rh	107	10	-	-	SYM
cord-322166-ajolu2rh	107	11	195	195	CD
cord-322166-ajolu2rh	107	12	,	,	,
cord-322166-ajolu2rh	107	13	and	and	CC
cord-322166-ajolu2rh	107	14	an	an	DT
cord-322166-ajolu2rh	107	15	aspartic	aspartic	JJ
cord-322166-ajolu2rh	107	16	acid	acid	NN
cord-322166-ajolu2rh	107	17	to	to	IN
cord-322166-ajolu2rh	107	18	glutamic	glutamic	NN
cord-322166-ajolu2rh	107	19	acid	acid	NN
cord-322166-ajolu2rh	107	20	substitution	substitution	NN
cord-322166-ajolu2rh	107	21	at	at	IN
cord-322166-ajolu2rh	107	22	NS1	ns1	NN
cord-322166-ajolu2rh	107	23	residue	residue	NN
cord-322166-ajolu2rh	107	24	92	92	CD
cord-322166-ajolu2rh	107	25	(	(	-LRB-
cord-322166-ajolu2rh	107	26	D92E	D92E	NNP
cord-322166-ajolu2rh	107	27	)	)	-RRB-
cord-322166-ajolu2rh	107	28	,	,	,
cord-322166-ajolu2rh	107	29	also	also	RB
cord-322166-ajolu2rh	107	30	enhance	enhance	VB
cord-322166-ajolu2rh	107	31	the	the	DT
cord-322166-ajolu2rh	107	32	virulence	virulence	NN
cord-322166-ajolu2rh	107	33	of	of	IN
cord-322166-ajolu2rh	107	34	H5N1	H5N1	NNP
cord-322166-ajolu2rh	107	35	by	by	IN
cord-322166-ajolu2rh	107	36	influencing	influence	VBG
cord-322166-ajolu2rh	107	37	the	the	DT
cord-322166-ajolu2rh	107	38	virus	virus	NN
cord-322166-ajolu2rh	107	39	titers	titer	NNS
cord-322166-ajolu2rh	107	40	and	and	CC
cord-322166-ajolu2rh	107	41	the	the	DT
cord-322166-ajolu2rh	107	42	expression	expression	NN
cord-322166-ajolu2rh	107	43	of	of	IN
cord-322166-ajolu2rh	107	44	pro	pro	JJ
cord-322166-ajolu2rh	107	45	-	-	JJ
cord-322166-ajolu2rh	107	46	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	107	47	cytokines	cytokine	NNS
cord-322166-ajolu2rh	107	48	(	(	-LRB-
cord-322166-ajolu2rh	107	49	e.g.	e.g.	RB
cord-322166-ajolu2rh	107	50	,	,	,
cord-322166-ajolu2rh	107	51	IFNs	ifn	NNS
cord-322166-ajolu2rh	107	52	and	and	CC
cord-322166-ajolu2rh	107	53	TNF	TNF	NNP
cord-322166-ajolu2rh	107	54	-	-	HYPH
cord-322166-ajolu2rh	107	55	α	α	NNP
cord-322166-ajolu2rh	107	56	)	)	-RRB-
cord-322166-ajolu2rh	107	57	(	(	-LRB-
cord-322166-ajolu2rh	107	58	Li	Li	NNP
cord-322166-ajolu2rh	107	59	W	W	NNP
cord-322166-ajolu2rh	107	60	,	,	,
cord-322166-ajolu2rh	107	61	et	et	NNP
cord-322166-ajolu2rh	107	62	al	al	NNP
cord-322166-ajolu2rh	107	63	.	.	NNP
cord-322166-ajolu2rh	107	64	,	,	,
cord-322166-ajolu2rh	107	65	2010	2010	CD
cord-322166-ajolu2rh	107	66	;	;	:
cord-322166-ajolu2rh	107	67	Lipatov	Lipatov	NNP
cord-322166-ajolu2rh	107	68	A	A	NNP
cord-322166-ajolu2rh	107	69	S	S	NNP
cord-322166-ajolu2rh	107	70	,	,	,
cord-322166-ajolu2rh	107	71	et	et	NNP
cord-322166-ajolu2rh	107	72	al	al	NNP
cord-322166-ajolu2rh	107	73	.	.	NNP
cord-322166-ajolu2rh	107	74	,	,	,
cord-322166-ajolu2rh	107	75	2005	2005	CD
cord-322166-ajolu2rh	107	76	;	;	:
cord-322166-ajolu2rh	107	77	Zhu	Zhu	NNP
cord-322166-ajolu2rh	107	78	Q	Q	NNP
cord-322166-ajolu2rh	107	79	,	,	,
cord-322166-ajolu2rh	107	80	et	et	NNP
cord-322166-ajolu2rh	107	81	al	al	NNP
cord-322166-ajolu2rh	107	82	.	.	NNP
cord-322166-ajolu2rh	107	83	,	,	,
cord-322166-ajolu2rh	107	84	2008	2008	CD
cord-322166-ajolu2rh	107	85	)	)	-RRB-
cord-322166-ajolu2rh	107	86	.	.	.
cord-322166-ajolu2rh	108	1	The	the	DT
cord-322166-ajolu2rh	108	2	E92	E92	NNP
cord-322166-ajolu2rh	108	3	residue	residue	NN
cord-322166-ajolu2rh	108	4	was	be	VBD
cord-322166-ajolu2rh	108	5	found	find	VBN
cord-322166-ajolu2rh	108	6	in	in	IN
cord-322166-ajolu2rh	108	7	viruses	virus	NNS
cord-322166-ajolu2rh	108	8	that	that	WDT
cord-322166-ajolu2rh	108	9	were	be	VBD
cord-322166-ajolu2rh	108	10	isolated	isolate	VBN
cord-322166-ajolu2rh	108	11	during	during	IN
cord-322166-ajolu2rh	108	12	the	the	DT
cord-322166-ajolu2rh	108	13	1997	1997	CD
cord-322166-ajolu2rh	108	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	108	15	outbreak	outbreak	NN
cord-322166-ajolu2rh	108	16	(	(	-LRB-
cord-322166-ajolu2rh	108	17	Lipatov	Lipatov	NNP
cord-322166-ajolu2rh	108	18	A	A	NNP
cord-322166-ajolu2rh	108	19	S	S	NNP
cord-322166-ajolu2rh	108	20	,	,	,
cord-322166-ajolu2rh	108	21	et	et	NNP
cord-322166-ajolu2rh	108	22	al	al	NNP
cord-322166-ajolu2rh	108	23	.	.	NNP
cord-322166-ajolu2rh	108	24	,	,	,
cord-322166-ajolu2rh	108	25	2005	2005	CD
cord-322166-ajolu2rh	108	26	)	)	-RRB-
cord-322166-ajolu2rh	108	27	.	.	.
cord-322166-ajolu2rh	109	1	This	this	DT
cord-322166-ajolu2rh	109	2	confirmed	confirm	VBD
cord-322166-ajolu2rh	109	3	the	the	DT
cord-322166-ajolu2rh	109	4	presumption	presumption	NN
cord-322166-ajolu2rh	109	5	that	that	WDT
cord-322166-ajolu2rh	109	6	NS1	ns1	UH
cord-322166-ajolu2rh	109	7	residue	residue	NN
cord-322166-ajolu2rh	109	8	E92	E92	NNP
cord-322166-ajolu2rh	109	9	of	of	IN
cord-322166-ajolu2rh	109	10	the	the	DT
cord-322166-ajolu2rh	109	11	HPAI	HPAI	NNP
cord-322166-ajolu2rh	109	12	H5N1	H5N1	NNP
cord-322166-ajolu2rh	109	13	may	may	MD
cord-322166-ajolu2rh	109	14	be	be	VB
cord-322166-ajolu2rh	109	15	crucial	crucial	JJ
cord-322166-ajolu2rh	109	16	for	for	IN
cord-322166-ajolu2rh	109	17	pathogenicity	pathogenicity	NN
cord-322166-ajolu2rh	109	18	(	(	-LRB-
cord-322166-ajolu2rh	109	19	Medina	Medina	NNP
cord-322166-ajolu2rh	109	20	R	R	NNP
cord-322166-ajolu2rh	109	21	A	A	NNP
cord-322166-ajolu2rh	109	22	,	,	,
cord-322166-ajolu2rh	109	23	et	et	NNP
cord-322166-ajolu2rh	109	24	al	al	NNP
cord-322166-ajolu2rh	109	25	.	.	NNP
cord-322166-ajolu2rh	109	26	,	,	,
cord-322166-ajolu2rh	109	27	2011	2011	CD
cord-322166-ajolu2rh	109	28	;	;	:
cord-322166-ajolu2rh	109	29	Seo	Seo	NNP
cord-322166-ajolu2rh	109	30	S	S	NNP
cord-322166-ajolu2rh	109	31	H	H	NNP
cord-322166-ajolu2rh	109	32	,	,	,
cord-322166-ajolu2rh	109	33	et	et	NNP
cord-322166-ajolu2rh	109	34	al	al	NNP
cord-322166-ajolu2rh	109	35	.	.	NNP
cord-322166-ajolu2rh	109	36	,	,	,
cord-322166-ajolu2rh	109	37	2002	2002	CD
cord-322166-ajolu2rh	109	38	)	)	-RRB-
cord-322166-ajolu2rh	109	39	.	.	.
cord-322166-ajolu2rh	110	1	Furthermore	furthermore	RB
cord-322166-ajolu2rh	110	2	,	,	,
cord-322166-ajolu2rh	110	3	the	the	DT
cord-322166-ajolu2rh	110	4	existence	existence	NN
cord-322166-ajolu2rh	110	5	of	of	IN
cord-322166-ajolu2rh	110	6	other	other	JJ
cord-322166-ajolu2rh	110	7	NS1	ns1	NN
cord-322166-ajolu2rh	110	8	gene	gene	NN
cord-322166-ajolu2rh	110	9	alleles	allele	NNS
cord-322166-ajolu2rh	110	10	exhibiting	exhibit	VBG
cord-322166-ajolu2rh	110	11	versatile	versatile	JJ
cord-322166-ajolu2rh	110	12	abilities	ability	NNS
cord-322166-ajolu2rh	110	13	to	to	TO
cord-322166-ajolu2rh	110	14	inhibit	inhibit	VB
cord-322166-ajolu2rh	110	15	the	the	DT
cord-322166-ajolu2rh	110	16	IFN	IFN	NNP
cord-322166-ajolu2rh	110	17	responses	response	NNS
cord-322166-ajolu2rh	110	18	underscores	underscore	VBZ
cord-322166-ajolu2rh	110	19	the	the	DT
cord-322166-ajolu2rh	110	20	importance	importance	NN
cord-322166-ajolu2rh	110	21	of	of	IN
cord-322166-ajolu2rh	110	22	NS1	ns1	NN
cord-322166-ajolu2rh	110	23	for	for	IN
cord-322166-ajolu2rh	110	24	H5N1	H5N1	NNP
cord-322166-ajolu2rh	110	25	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	110	26	(	(	-LRB-
cord-322166-ajolu2rh	110	27	Munir	Munir	NNP
cord-322166-ajolu2rh	110	28	M	M	NNP
cord-322166-ajolu2rh	110	29	,	,	,
cord-322166-ajolu2rh	110	30	et	et	NNP
cord-322166-ajolu2rh	110	31	al	al	NNP
cord-322166-ajolu2rh	110	32	.	.	NNP
cord-322166-ajolu2rh	110	33	,	,	,
cord-322166-ajolu2rh	110	34	2011	2011	CD
cord-322166-ajolu2rh	110	35	)	)	-RRB-
cord-322166-ajolu2rh	110	36	.	.	.
cord-322166-ajolu2rh	111	1	Other	other	JJ
cord-322166-ajolu2rh	111	2	AIV	AIV	NNP
cord-322166-ajolu2rh	111	3	proteins	protein	NNS
cord-322166-ajolu2rh	111	4	,	,	,
cord-322166-ajolu2rh	111	5	such	such	JJ
cord-322166-ajolu2rh	111	6	as	as	IN
cord-322166-ajolu2rh	111	7	PA	PA	NNP
cord-322166-ajolu2rh	111	8	,	,	,
cord-322166-ajolu2rh	111	9	PB1	PB1	NNP
cord-322166-ajolu2rh	111	10	,	,	,
cord-322166-ajolu2rh	111	11	PB2	PB2	NNP
cord-322166-ajolu2rh	111	12	,	,	,
cord-322166-ajolu2rh	111	13	M1	M1	NNP
cord-322166-ajolu2rh	111	14	,	,	,
cord-322166-ajolu2rh	111	15	and	and	CC
cord-322166-ajolu2rh	111	16	M2	M2	NNP
cord-322166-ajolu2rh	111	17	can	can	MD
cord-322166-ajolu2rh	111	18	also	also	RB
cord-322166-ajolu2rh	111	19	alter	alter	VB
cord-322166-ajolu2rh	111	20	virus	virus	NN
cord-322166-ajolu2rh	111	21	virulence	virulence	NN
cord-322166-ajolu2rh	111	22	and	and	CC
cord-322166-ajolu2rh	111	23	transmission	transmission	NN
cord-322166-ajolu2rh	111	24	,	,	,
cord-322166-ajolu2rh	111	25	increasing	increase	VBG
cord-322166-ajolu2rh	111	26	the	the	DT
cord-322166-ajolu2rh	111	27	pandemic	pandemic	NN
cord-322166-ajolu2rh	111	28	potential	potential	NN
cord-322166-ajolu2rh	111	29	for	for	IN
cord-322166-ajolu2rh	111	30	this	this	DT
cord-322166-ajolu2rh	111	31	virus	virus	NN
cord-322166-ajolu2rh	111	32	.	.	.
cord-322166-ajolu2rh	112	1	(	(	-LRB-
cord-322166-ajolu2rh	112	2	Gao	Gao	NNP
cord-322166-ajolu2rh	112	3	Y	Y	NNP
cord-322166-ajolu2rh	112	4	,	,	,
cord-322166-ajolu2rh	112	5	et	et	NNP
cord-322166-ajolu2rh	112	6	al	al	NNP
cord-322166-ajolu2rh	112	7	.	.	NNP
cord-322166-ajolu2rh	112	8	,	,	,
cord-322166-ajolu2rh	112	9	2009	2009	CD
cord-322166-ajolu2rh	112	10	;	;	:
cord-322166-ajolu2rh	112	11	Guan	Guan	NNP
cord-322166-ajolu2rh	112	12	Y	Y	NNP
cord-322166-ajolu2rh	112	13	,	,	,
cord-322166-ajolu2rh	112	14	et	et	NNP
cord-322166-ajolu2rh	112	15	al	al	NNP
cord-322166-ajolu2rh	112	16	.	.	NNP
cord-322166-ajolu2rh	112	17	,	,	,
cord-322166-ajolu2rh	112	18	2002	2002	CD
cord-322166-ajolu2rh	112	19	;	;	:
cord-322166-ajolu2rh	112	20	Tafforeau	Tafforeau	NNP
cord-322166-ajolu2rh	112	21	L	L	NNP
cord-322166-ajolu2rh	112	22	,	,	,
cord-322166-ajolu2rh	112	23	et	et	NNP
cord-322166-ajolu2rh	112	24	al	al	NNP
cord-322166-ajolu2rh	112	25	.	.	NNP
cord-322166-ajolu2rh	112	26	,	,	,
cord-322166-ajolu2rh	112	27	2011	2011	CD
cord-322166-ajolu2rh	112	28	;	;	:
cord-322166-ajolu2rh	112	29	Thanh	Thanh	NNP
cord-322166-ajolu2rh	112	30	T	T	NNP
cord-322166-ajolu2rh	112	31	T	T	NNP
cord-322166-ajolu2rh	112	32	,	,	,
cord-322166-ajolu2rh	112	33	et	et	NNP
cord-322166-ajolu2rh	112	34	al	al	NNP
cord-322166-ajolu2rh	112	35	.	.	NNP
cord-322166-ajolu2rh	112	36	,	,	,
cord-322166-ajolu2rh	112	37	2008	2008	CD
cord-322166-ajolu2rh	112	38	;	;	:
cord-322166-ajolu2rh	112	39	Wasilenko	Wasilenko	NNP
cord-322166-ajolu2rh	112	40	J	J	NNP
cord-322166-ajolu2rh	112	41	L	L	NNP
cord-322166-ajolu2rh	112	42	,	,	,
cord-322166-ajolu2rh	112	43	et	et	NNP
cord-322166-ajolu2rh	112	44	al	al	NNP
cord-322166-ajolu2rh	112	45	.	.	NNP
cord-322166-ajolu2rh	112	46	,	,	,
cord-322166-ajolu2rh	112	47	2008	2008	CD
cord-322166-ajolu2rh	112	48	;	;	:
cord-322166-ajolu2rh	112	49	Zamarin	Zamarin	NNP
cord-322166-ajolu2rh	112	50	D	D	NNP
cord-322166-ajolu2rh	112	51	,	,	,
cord-322166-ajolu2rh	112	52	et	et	NNP
cord-322166-ajolu2rh	112	53	al	al	NNP
cord-322166-ajolu2rh	112	54	.	.	NNP
cord-322166-ajolu2rh	112	55	,	,	,
cord-322166-ajolu2rh	112	56	2006	2006	CD
cord-322166-ajolu2rh	112	57	)	)	-RRB-
cord-322166-ajolu2rh	112	58	.	.	.
cord-322166-ajolu2rh	113	1	A	a	DT
cord-322166-ajolu2rh	113	2	study	study	NN
cord-322166-ajolu2rh	113	3	has	have	VBZ
cord-322166-ajolu2rh	113	4	shown	show	VBN
cord-322166-ajolu2rh	113	5	that	that	IN
cord-322166-ajolu2rh	113	6	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	113	7	interacts	interact	VBZ
cord-322166-ajolu2rh	113	8	with	with	IN
cord-322166-ajolu2rh	113	9	two	two	CD
cord-322166-ajolu2rh	113	10	mitochondrial	mitochondrial	JJ
cord-322166-ajolu2rh	113	11	proteins	protein	NNS
cord-322166-ajolu2rh	113	12	,	,	,
cord-322166-ajolu2rh	113	13	adenine	adenine	NN
cord-322166-ajolu2rh	113	14	nucleotide	nucleotide	JJ
cord-322166-ajolu2rh	113	15	translocator	translocator	NN
cord-322166-ajolu2rh	113	16	3	3	CD
cord-322166-ajolu2rh	113	17	and	and	CC
cord-322166-ajolu2rh	113	18	voltage	voltage	VB
cord-322166-ajolu2rh	113	19	-	-	HYPH
cord-322166-ajolu2rh	113	20	dependent	dependent	JJ
cord-322166-ajolu2rh	113	21	anion	anion	NN
cord-322166-ajolu2rh	113	22	channel	channel	NN
cord-322166-ajolu2rh	113	23	1	1	CD
cord-322166-ajolu2rh	113	24	,	,	,
cord-322166-ajolu2rh	113	25	which	which	WDT
cord-322166-ajolu2rh	113	26	induces	induce	VBZ
cord-322166-ajolu2rh	113	27	apoptosis	apoptosis	NN
cord-322166-ajolu2rh	113	28	(	(	-LRB-
cord-322166-ajolu2rh	113	29	Zamarin	Zamarin	NNP
cord-322166-ajolu2rh	113	30	D	D	NNP
cord-322166-ajolu2rh	113	31	,	,	,
cord-322166-ajolu2rh	113	32	et	et	NNP
cord-322166-ajolu2rh	113	33	al	al	NNP
cord-322166-ajolu2rh	113	34	.	.	NNP
cord-322166-ajolu2rh	113	35	,	,	,
cord-322166-ajolu2rh	113	36	2005	2005	CD
cord-322166-ajolu2rh	113	37	)	)	-RRB-
cord-322166-ajolu2rh	113	38	.	.	.
cord-322166-ajolu2rh	114	1	Silencing	silencing	NN
cord-322166-ajolu2rh	114	2	of	of	IN
cord-322166-ajolu2rh	114	3	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	114	4	protein	protein	NN
cord-322166-ajolu2rh	114	5	expression	expression	NN
cord-322166-ajolu2rh	114	6	by	by	IN
cord-322166-ajolu2rh	114	7	short	short	JJ
cord-322166-ajolu2rh	114	8	interfering	interfere	VBG
cord-322166-ajolu2rh	114	9	RNA	RNA	NNP
cord-322166-ajolu2rh	114	10	diminished	diminish	VBD
cord-322166-ajolu2rh	114	11	AIV	AIV	NNP
cord-322166-ajolu2rh	114	12	pathogenicity	pathogenicity	NN
cord-322166-ajolu2rh	114	13	and	and	CC
cord-322166-ajolu2rh	114	14	mortality	mortality	NN
cord-322166-ajolu2rh	114	15	in	in	IN
cord-322166-ajolu2rh	114	16	mice	mouse	NNS
cord-322166-ajolu2rh	114	17	without	without	IN
cord-322166-ajolu2rh	114	18	affecting	affect	VBG
cord-322166-ajolu2rh	114	19	viral	viral	JJ
cord-322166-ajolu2rh	114	20	replication	replication	NN
cord-322166-ajolu2rh	114	21	kinetics	kinetic	NNS
cord-322166-ajolu2rh	114	22	in	in	IN
cord-322166-ajolu2rh	114	23	cell	cell	NN
cord-322166-ajolu2rh	114	24	culture	culture	NN
cord-322166-ajolu2rh	114	25	(	(	-LRB-
cord-322166-ajolu2rh	114	26	Zamarin	Zamarin	NNP
cord-322166-ajolu2rh	114	27	D	D	NNP
cord-322166-ajolu2rh	114	28	,	,	,
cord-322166-ajolu2rh	114	29	et	et	NNP
cord-322166-ajolu2rh	114	30	al	al	NNP
cord-322166-ajolu2rh	114	31	.	.	NNP
cord-322166-ajolu2rh	114	32	,	,	,
cord-322166-ajolu2rh	114	33	2006	2006	CD
cord-322166-ajolu2rh	114	34	)	)	-RRB-
cord-322166-ajolu2rh	114	35	.	.	.
cord-322166-ajolu2rh	115	1	Another	another	DT
cord-322166-ajolu2rh	115	2	study	study	NN
cord-322166-ajolu2rh	115	3	showed	show	VBD
cord-322166-ajolu2rh	115	4	that	that	IN
cord-322166-ajolu2rh	115	5	mutation	mutation	NN
cord-322166-ajolu2rh	115	6	of	of	IN
cord-322166-ajolu2rh	115	7	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	115	8	residue	residue	NN
cord-322166-ajolu2rh	115	9	N66S	n66s	NN
cord-322166-ajolu2rh	115	10	delayed	delay	VBN
cord-322166-ajolu2rh	115	11	activation	activation	NN
cord-322166-ajolu2rh	115	12	of	of	IN
cord-322166-ajolu2rh	115	13	type	type	NN
cord-322166-ajolu2rh	116	1	I	-PRON-	PRP
cord-322166-ajolu2rh	116	2	IFN	IFN	NNP
cord-322166-ajolu2rh	116	3	pathway	pathway	NN
cord-322166-ajolu2rh	116	4	genes	gene	NNS
cord-322166-ajolu2rh	116	5	(	(	-LRB-
cord-322166-ajolu2rh	116	6	Conenello	Conenello	NNP
cord-322166-ajolu2rh	116	7	G	G	NNP
cord-322166-ajolu2rh	116	8	M	M	NNP
cord-322166-ajolu2rh	116	9	,	,	,
cord-322166-ajolu2rh	116	10	et	et	NNP
cord-322166-ajolu2rh	116	11	al	al	NNP
cord-322166-ajolu2rh	116	12	.	.	NNP
cord-322166-ajolu2rh	116	13	,	,	,
cord-322166-ajolu2rh	116	14	2011	2011	CD
cord-322166-ajolu2rh	116	15	)	)	-RRB-
cord-322166-ajolu2rh	116	16	.	.	.
cord-322166-ajolu2rh	117	1	Similar	similar	JJ
cord-322166-ajolu2rh	117	2	studies	study	NNS
cord-322166-ajolu2rh	117	3	have	have	VBP
cord-322166-ajolu2rh	117	4	confirmed	confirm	VBN
cord-322166-ajolu2rh	117	5	that	that	IN
cord-322166-ajolu2rh	117	6	mutations	mutation	NNS
cord-322166-ajolu2rh	117	7	at	at	IN
cord-322166-ajolu2rh	117	8	single	single	JJ
cord-322166-ajolu2rh	117	9	residues	residue	NNS
cord-322166-ajolu2rh	117	10	in	in	IN
cord-322166-ajolu2rh	117	11	multiple	multiple	JJ
cord-322166-ajolu2rh	117	12	AIV	aiv	NN
cord-322166-ajolu2rh	117	13	proteins	protein	NNS
cord-322166-ajolu2rh	117	14	were	be	VBD
cord-322166-ajolu2rh	117	15	associated	associate	VBN
cord-322166-ajolu2rh	117	16	with	with	IN
cord-322166-ajolu2rh	117	17	increased	increase	VBN
cord-322166-ajolu2rh	117	18	(	(	-LRB-
cord-322166-ajolu2rh	117	19	or	or	CC
cord-322166-ajolu2rh	117	20	decreased	decrease	VBN
cord-322166-ajolu2rh	117	21	)	)	-RRB-
cord-322166-ajolu2rh	117	22	virulence	virulence	NN
cord-322166-ajolu2rh	117	23	.	.	.
cord-322166-ajolu2rh	118	1	For	for	IN
cord-322166-ajolu2rh	118	2	example	example	NN
cord-322166-ajolu2rh	118	3	,	,	,
cord-322166-ajolu2rh	118	4	residue	residue	JJ
cord-322166-ajolu2rh	118	5	K627	K627	NNS
cord-322166-ajolu2rh	118	6	in	in	IN
cord-322166-ajolu2rh	118	7	PB2	PB2	NNP
cord-322166-ajolu2rh	118	8	has	have	VBZ
cord-322166-ajolu2rh	118	9	been	be	VBN
cord-322166-ajolu2rh	118	10	detected	detect	VBN
cord-322166-ajolu2rh	118	11	in	in	IN
cord-322166-ajolu2rh	118	12	human	human	JJ
cord-322166-ajolu2rh	118	13	HPAI	HPAI	NNP
cord-322166-ajolu2rh	118	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	118	15	viruses	virus	NNS
cord-322166-ajolu2rh	118	16	and	and	CC
cord-322166-ajolu2rh	118	17	shown	show	VBN
cord-322166-ajolu2rh	118	18	to	to	TO
cord-322166-ajolu2rh	118	19	be	be	VB
cord-322166-ajolu2rh	118	20	a	a	DT
cord-322166-ajolu2rh	118	21	host	host	NN
cord-322166-ajolu2rh	118	22	range	range	NN
cord-322166-ajolu2rh	118	23	determinant	determinant	NN
cord-322166-ajolu2rh	118	24	,	,	,
cord-322166-ajolu2rh	118	25	but	but	CC
cord-322166-ajolu2rh	118	26	a	a	DT
cord-322166-ajolu2rh	118	27	D701N	d701n	NN
cord-322166-ajolu2rh	118	28	mutation	mutation	NN
cord-322166-ajolu2rh	118	29	of	of	IN
cord-322166-ajolu2rh	118	30	PB2	PB2	NNP
cord-322166-ajolu2rh	118	31	can	can	MD
cord-322166-ajolu2rh	118	32	also	also	RB
cord-322166-ajolu2rh	118	33	enable	enable	VB
cord-322166-ajolu2rh	118	34	AIV	AIV	NNP
cord-322166-ajolu2rh	118	35	to	to	TO
cord-322166-ajolu2rh	118	36	infect	infect	VB
cord-322166-ajolu2rh	118	37	mammalian	mammalian	JJ
cord-322166-ajolu2rh	118	38	cells	cell	NNS
cord-322166-ajolu2rh	118	39	(	(	-LRB-
cord-322166-ajolu2rh	118	40	de	de	FW
cord-322166-ajolu2rh	118	41	Jong	Jong	NNP
cord-322166-ajolu2rh	118	42	M	M	NNP
cord-322166-ajolu2rh	118	43	D	D	NNP
cord-322166-ajolu2rh	118	44	,	,	,
cord-322166-ajolu2rh	118	45	et	et	NNP
cord-322166-ajolu2rh	118	46	al	al	NNP
cord-322166-ajolu2rh	118	47	.	.	NNP
cord-322166-ajolu2rh	118	48	,	,	,
cord-322166-ajolu2rh	118	49	2006	2006	CD
cord-322166-ajolu2rh	118	50	;	;	:
cord-322166-ajolu2rh	118	51	Gabriel	Gabriel	NNP
cord-322166-ajolu2rh	118	52	G	G	NNP
cord-322166-ajolu2rh	118	53	,	,	,
cord-322166-ajolu2rh	118	54	et	et	NNP
cord-322166-ajolu2rh	118	55	al	al	NNP
cord-322166-ajolu2rh	118	56	.	.	NNP
cord-322166-ajolu2rh	118	57	,	,	,
cord-322166-ajolu2rh	118	58	2005	2005	CD
cord-322166-ajolu2rh	118	59	;	;	:
cord-322166-ajolu2rh	118	60	Subbarao	Subbarao	NNP
cord-322166-ajolu2rh	118	61	E	E	NNP
cord-322166-ajolu2rh	118	62	K	K	NNP
cord-322166-ajolu2rh	118	63	,	,	,
cord-322166-ajolu2rh	118	64	et	et	NNP
cord-322166-ajolu2rh	118	65	al	al	NNP
cord-322166-ajolu2rh	118	66	.	.	NNP
cord-322166-ajolu2rh	118	67	,	,	,
cord-322166-ajolu2rh	118	68	1993	1993	CD
cord-322166-ajolu2rh	118	69	)	)	-RRB-
cord-322166-ajolu2rh	118	70	.	.	.
cord-322166-ajolu2rh	119	1	In	in	IN
cord-322166-ajolu2rh	119	2	addition	addition	NN
cord-322166-ajolu2rh	119	3	,	,	,
cord-322166-ajolu2rh	119	4	some	some	DT
cord-322166-ajolu2rh	119	5	poultry	poultry	NN
cord-322166-ajolu2rh	119	6	-	-	HYPH
cord-322166-ajolu2rh	119	7	derived	derive	VBN
cord-322166-ajolu2rh	119	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	119	9	viruses	virus	NNS
cord-322166-ajolu2rh	119	10	can	can	MD
cord-322166-ajolu2rh	119	11	cross	cross	VB
cord-322166-ajolu2rh	119	12	the	the	DT
cord-322166-ajolu2rh	119	13	species	specie	NNS
cord-322166-ajolu2rh	119	14	barrier	barrier	NN
cord-322166-ajolu2rh	119	15	and	and	CC
cord-322166-ajolu2rh	119	16	replicate	replicate	VB
cord-322166-ajolu2rh	119	17	in	in	IN
cord-322166-ajolu2rh	119	18	mammalian	mammalian	JJ
cord-322166-ajolu2rh	119	19	cells	cell	NNS
cord-322166-ajolu2rh	119	20	without	without	IN
cord-322166-ajolu2rh	119	21	additional	additional	JJ
cord-322166-ajolu2rh	119	22	mutations	mutation	NNS
cord-322166-ajolu2rh	119	23	,	,	,
cord-322166-ajolu2rh	119	24	indicating	indicate	VBG
cord-322166-ajolu2rh	119	25	that	that	IN
cord-322166-ajolu2rh	119	26	mammal	mammal	NN
cord-322166-ajolu2rh	119	27	-	-	HYPH
cord-322166-ajolu2rh	119	28	adapted	adapt	VBN
cord-322166-ajolu2rh	119	29	AIVs	aiv	NNS
cord-322166-ajolu2rh	119	30	may	may	MD
cord-322166-ajolu2rh	119	31	exist	exist	VB
cord-322166-ajolu2rh	119	32	in	in	IN
cord-322166-ajolu2rh	119	33	nature	nature	NN
cord-322166-ajolu2rh	120	1	(	(	-LRB-
cord-322166-ajolu2rh	120	2	Suksatu	Suksatu	NNP
cord-322166-ajolu2rh	120	3	A	A	NNP
cord-322166-ajolu2rh	120	4	,	,	,
cord-322166-ajolu2rh	120	5	et	et	NNP
cord-322166-ajolu2rh	120	6	al	al	NNP
cord-322166-ajolu2rh	120	7	.	.	NNP
cord-322166-ajolu2rh	120	8	,	,	,
cord-322166-ajolu2rh	120	9	2009	2009	CD
cord-322166-ajolu2rh	120	10	)	)	-RRB-
cord-322166-ajolu2rh	120	11	.	.	.
cord-322166-ajolu2rh	121	1	The	the	DT
cord-322166-ajolu2rh	121	2	malleable	malleable	JJ
cord-322166-ajolu2rh	121	3	nature	nature	NN
cord-322166-ajolu2rh	121	4	of	of	IN
cord-322166-ajolu2rh	121	5	influenza	influenza	NN
cord-322166-ajolu2rh	121	6	virus	virus	NN
cord-322166-ajolu2rh	121	7	,	,	,
cord-322166-ajolu2rh	121	8	and	and	CC
cord-322166-ajolu2rh	121	9	the	the	DT
cord-322166-ajolu2rh	121	10	complex	complex	JJ
cord-322166-ajolu2rh	121	11	biological	biological	JJ
cord-322166-ajolu2rh	121	12	characteristics	characteristic	NNS
cord-322166-ajolu2rh	121	13	of	of	IN
cord-322166-ajolu2rh	121	14	the	the	DT
cord-322166-ajolu2rh	121	15	H5N1	H5N1	NNP
cord-322166-ajolu2rh	121	16	avian	avian	JJ
cord-322166-ajolu2rh	121	17	virus	virus	NN
cord-322166-ajolu2rh	121	18	pose	pose	VBP
cord-322166-ajolu2rh	121	19	a	a	DT
cord-322166-ajolu2rh	121	20	challenge	challenge	NN
cord-322166-ajolu2rh	121	21	for	for	IN
cord-322166-ajolu2rh	121	22	the	the	DT
cord-322166-ajolu2rh	121	23	development	development	NN
cord-322166-ajolu2rh	121	24	of	of	IN
cord-322166-ajolu2rh	121	25	vaccines	vaccine	NNS
cord-322166-ajolu2rh	121	26	and	and	CC
cord-322166-ajolu2rh	121	27	antiviral	antiviral	JJ
cord-322166-ajolu2rh	121	28	drugs	drug	NNS
cord-322166-ajolu2rh	121	29	needed	need	VBD
cord-322166-ajolu2rh	121	30	to	to	TO
cord-322166-ajolu2rh	121	31	counter	counter	VB
cord-322166-ajolu2rh	121	32	pandemic	pandemic	JJ
cord-322166-ajolu2rh	121	33	spread	spread	NN
cord-322166-ajolu2rh	121	34	of	of	IN
cord-322166-ajolu2rh	121	35	this	this	DT
cord-322166-ajolu2rh	121	36	influenza	influenza	NN
cord-322166-ajolu2rh	121	37	virus	virus	NN
cord-322166-ajolu2rh	121	38	(	(	-LRB-
cord-322166-ajolu2rh	121	39	Guan	Guan	NNP
cord-322166-ajolu2rh	121	40	Y	Y	NNP
cord-322166-ajolu2rh	121	41	,	,	,
cord-322166-ajolu2rh	121	42	et	et	NNP
cord-322166-ajolu2rh	121	43	al	al	NNP
cord-322166-ajolu2rh	121	44	.	.	NNP
cord-322166-ajolu2rh	121	45	,	,	,
cord-322166-ajolu2rh	121	46	2002	2002	CD
cord-322166-ajolu2rh	121	47	)	)	-RRB-
cord-322166-ajolu2rh	121	48	.	.	.
cord-322166-ajolu2rh	122	1	The	the	DT
cord-322166-ajolu2rh	122	2	time	time	NN
cord-322166-ajolu2rh	122	3	from	from	IN
cord-322166-ajolu2rh	122	4	H5N1	H5N1	NNP
cord-322166-ajolu2rh	122	5	virus	virus	NN
cord-322166-ajolu2rh	122	6	exposure	exposure	NN
cord-322166-ajolu2rh	122	7	to	to	IN
cord-322166-ajolu2rh	122	8	onset	onset	NN
cord-322166-ajolu2rh	122	9	of	of	IN
cord-322166-ajolu2rh	122	10	symptoms	symptom	NNS
cord-322166-ajolu2rh	122	11	ranges	range	VBZ
cord-322166-ajolu2rh	122	12	from	from	IN
cord-322166-ajolu2rh	122	13	one	one	CD
cord-322166-ajolu2rh	122	14	to	to	TO
cord-322166-ajolu2rh	122	15	seven	seven	CD
cord-322166-ajolu2rh	122	16	days	day	NNS
cord-322166-ajolu2rh	122	17	.	.	.
cord-322166-ajolu2rh	123	1	The	the	DT
cord-322166-ajolu2rh	123	2	majority	majority	NN
cord-322166-ajolu2rh	123	3	of	of	IN
cord-322166-ajolu2rh	123	4	reported	report	VBN
cord-322166-ajolu2rh	123	5	cases	case	NNS
cord-322166-ajolu2rh	123	6	have	have	VBP
cord-322166-ajolu2rh	123	7	been	be	VBN
cord-322166-ajolu2rh	123	8	in	in	IN
cord-322166-ajolu2rh	123	9	infants	infant	NNS
cord-322166-ajolu2rh	123	10	and	and	CC
cord-322166-ajolu2rh	123	11	young	young	JJ
cord-322166-ajolu2rh	123	12	children	child	NNS
cord-322166-ajolu2rh	124	1	(	(	-LRB-
cord-322166-ajolu2rh	124	2	Beigel	Beigel	NNP
cord-322166-ajolu2rh	124	3	J	J	NNP
cord-322166-ajolu2rh	124	4	H	H	NNP
cord-322166-ajolu2rh	124	5	,	,	,
cord-322166-ajolu2rh	124	6	et	et	NNP
cord-322166-ajolu2rh	124	7	al	al	NNP
cord-322166-ajolu2rh	124	8	.	.	NNP
cord-322166-ajolu2rh	124	9	,	,	,
cord-322166-ajolu2rh	124	10	2005	2005	CD
cord-322166-ajolu2rh	124	11	)	)	-RRB-
cord-322166-ajolu2rh	124	12	.	.	.
cord-322166-ajolu2rh	125	1	The	the	DT
cord-322166-ajolu2rh	125	2	time	time	NN
cord-322166-ajolu2rh	125	3	from	from	IN
cord-322166-ajolu2rh	125	4	onset	onset	NN
cord-322166-ajolu2rh	125	5	of	of	IN
cord-322166-ajolu2rh	125	6	illness	illness	NN
cord-322166-ajolu2rh	125	7	to	to	IN
cord-322166-ajolu2rh	125	8	death	death	NN
cord-322166-ajolu2rh	125	9	can	can	MD
cord-322166-ajolu2rh	125	10	be	be	VB
cord-322166-ajolu2rh	125	11	as	as	RB
cord-322166-ajolu2rh	125	12	short	short	JJ
cord-322166-ajolu2rh	125	13	as	as	IN
cord-322166-ajolu2rh	125	14	few	few	JJ
cord-322166-ajolu2rh	125	15	days	day	NNS
cord-322166-ajolu2rh	125	16	to	to	IN
cord-322166-ajolu2rh	125	17	as	as	RB
cord-322166-ajolu2rh	125	18	long	long	RB
cord-322166-ajolu2rh	125	19	as	as	IN
cord-322166-ajolu2rh	125	20	one	one	CD
cord-322166-ajolu2rh	125	21	month	month	NN
cord-322166-ajolu2rh	125	22	,	,	,
cord-322166-ajolu2rh	125	23	most	most	RBS
cord-322166-ajolu2rh	125	24	likely	likely	RB
cord-322166-ajolu2rh	125	25	reflecting	reflect	VBG
cord-322166-ajolu2rh	125	26	different	different	JJ
cord-322166-ajolu2rh	125	27	environmental	environmental	JJ
cord-322166-ajolu2rh	125	28	conditions	condition	NNS
cord-322166-ajolu2rh	125	29	and	and	CC
cord-322166-ajolu2rh	125	30	characteristics	characteristic	NNS
cord-322166-ajolu2rh	125	31	of	of	IN
cord-322166-ajolu2rh	125	32	individual	individual	JJ
cord-322166-ajolu2rh	125	33	virus	virus	NN
cord-322166-ajolu2rh	125	34	strains	strain	VBZ
cord-322166-ajolu2rh	125	35	7	7	CD
cord-322166-ajolu2rh	126	1	(	(	-LRB-
cord-322166-ajolu2rh	126	2	Cattoli	Cattoli	NNP
cord-322166-ajolu2rh	126	3	G	G	NNP
cord-322166-ajolu2rh	126	4	,	,	,
cord-322166-ajolu2rh	126	5	et	et	NNP
cord-322166-ajolu2rh	126	6	al	al	NNP
cord-322166-ajolu2rh	126	7	.	.	NNP
cord-322166-ajolu2rh	126	8	,	,	,
cord-322166-ajolu2rh	126	9	2009	2009	CD
cord-322166-ajolu2rh	126	10	)	)	-RRB-
cord-322166-ajolu2rh	126	11	.	.	.
cord-322166-ajolu2rh	127	1	Human	human	JJ
cord-322166-ajolu2rh	127	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	127	3	infection	infection	NN
cord-322166-ajolu2rh	127	4	is	be	VBZ
cord-322166-ajolu2rh	127	5	characterized	characterize	VBN
cord-322166-ajolu2rh	127	6	by	by	IN
cord-322166-ajolu2rh	127	7	high	high	JJ
cord-322166-ajolu2rh	127	8	pharyngeal	pharyngeal	JJ
cord-322166-ajolu2rh	127	9	virus	virus	NN
cord-322166-ajolu2rh	127	10	loads	load	NNS
cord-322166-ajolu2rh	127	11	and	and	CC
cord-322166-ajolu2rh	127	12	presence	presence	NN
cord-322166-ajolu2rh	127	13	of	of	IN
cord-322166-ajolu2rh	127	14	viral	viral	JJ
cord-322166-ajolu2rh	127	15	RNA	RNA	NNP
cord-322166-ajolu2rh	127	16	in	in	IN
cord-322166-ajolu2rh	127	17	the	the	DT
cord-322166-ajolu2rh	127	18	feces	fece	NNS
cord-322166-ajolu2rh	127	19	and	and	CC
cord-322166-ajolu2rh	127	20	blood	blood	NN
cord-322166-ajolu2rh	127	21	(	(	-LRB-
cord-322166-ajolu2rh	127	22	de	de	FW
cord-322166-ajolu2rh	127	23	Jong	Jong	NNP
cord-322166-ajolu2rh	127	24	M	M	NNP
cord-322166-ajolu2rh	127	25	D	D	NNP
cord-322166-ajolu2rh	127	26	,	,	,
cord-322166-ajolu2rh	127	27	et	et	NNP
cord-322166-ajolu2rh	127	28	al	al	NNP
cord-322166-ajolu2rh	127	29	.	.	NNP
cord-322166-ajolu2rh	127	30	,	,	,
cord-322166-ajolu2rh	127	31	2006	2006	CD
cord-322166-ajolu2rh	127	32	;	;	:
cord-322166-ajolu2rh	127	33	Wang	Wang	NNP
cord-322166-ajolu2rh	127	34	H	H	NNP
cord-322166-ajolu2rh	127	35	,	,	,
cord-322166-ajolu2rh	127	36	et	et	NNP
cord-322166-ajolu2rh	127	37	al	al	NNP
cord-322166-ajolu2rh	127	38	.	.	NNP
cord-322166-ajolu2rh	127	39	,	,	,
cord-322166-ajolu2rh	127	40	2009	2009	CD
cord-322166-ajolu2rh	127	41	)	)	-RRB-
cord-322166-ajolu2rh	127	42	.	.	.
cord-322166-ajolu2rh	128	1	The	the	DT
cord-322166-ajolu2rh	128	2	distribution	distribution	NN
cord-322166-ajolu2rh	128	3	of	of	IN
cord-322166-ajolu2rh	128	4	virus	virus	NN
cord-322166-ajolu2rh	128	5	isolates	isolate	NNS
cord-322166-ajolu2rh	128	6	and	and	CC
cord-322166-ajolu2rh	128	7	clinical	clinical	JJ
cord-322166-ajolu2rh	128	8	features	feature	NNS
cord-322166-ajolu2rh	128	9	of	of	IN
cord-322166-ajolu2rh	128	10	infection	infection	NN
cord-322166-ajolu2rh	128	11	vary	vary	VBP
cord-322166-ajolu2rh	128	12	considerably	considerably	RB
cord-322166-ajolu2rh	128	13	among	among	IN
cord-322166-ajolu2rh	128	14	host	host	NN
cord-322166-ajolu2rh	128	15	species	specie	NNS
cord-322166-ajolu2rh	129	1	(	(	-LRB-
cord-322166-ajolu2rh	129	2	Gao	Gao	NNP
cord-322166-ajolu2rh	129	3	P	P	NNP
cord-322166-ajolu2rh	129	4	,	,	,
cord-322166-ajolu2rh	129	5	et	et	NNP
cord-322166-ajolu2rh	129	6	al	al	NNP
cord-322166-ajolu2rh	129	7	.	.	NNP
cord-322166-ajolu2rh	129	8	,	,	,
cord-322166-ajolu2rh	129	9	1999	1999	CD
cord-322166-ajolu2rh	129	10	;	;	:
cord-322166-ajolu2rh	129	11	Kuiken	Kuiken	NNP
cord-322166-ajolu2rh	129	12	T	T	NNP
cord-322166-ajolu2rh	129	13	,	,	,
cord-322166-ajolu2rh	129	14	et	et	NNP
cord-322166-ajolu2rh	129	15	al	al	NNP
cord-322166-ajolu2rh	129	16	.	.	NNP
cord-322166-ajolu2rh	129	17	,	,	,
cord-322166-ajolu2rh	129	18	2010	2010	CD
cord-322166-ajolu2rh	129	19	)	)	-RRB-
cord-322166-ajolu2rh	129	20	.	.	.
cord-322166-ajolu2rh	130	1	For	for	IN
cord-322166-ajolu2rh	130	2	example	example	NN
cord-322166-ajolu2rh	130	3	,	,	,
cord-322166-ajolu2rh	130	4	although	although	IN
cord-322166-ajolu2rh	130	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	130	6	virus	virus	NN
cord-322166-ajolu2rh	130	7	can	can	MD
cord-322166-ajolu2rh	130	8	be	be	VB
cord-322166-ajolu2rh	130	9	found	find	VBN
cord-322166-ajolu2rh	130	10	in	in	IN
cord-322166-ajolu2rh	130	11	the	the	DT
cord-322166-ajolu2rh	130	12	brain	brain	NN
cord-322166-ajolu2rh	130	13	of	of	IN
cord-322166-ajolu2rh	130	14	experimentally	experimentally	RB
cord-322166-ajolu2rh	130	15	infected	infect	VBN
cord-322166-ajolu2rh	130	16	mice	mouse	NNS
cord-322166-ajolu2rh	130	17	,	,	,
cord-322166-ajolu2rh	130	18	it	-PRON-	PRP
cord-322166-ajolu2rh	130	19	is	be	VBZ
cord-322166-ajolu2rh	130	20	more	more	RBR
cord-322166-ajolu2rh	130	21	likely	likely	JJ
cord-322166-ajolu2rh	130	22	to	to	TO
cord-322166-ajolu2rh	130	23	infect	infect	VB
cord-322166-ajolu2rh	130	24	the	the	DT
cord-322166-ajolu2rh	130	25	heart	heart	NN
cord-322166-ajolu2rh	130	26	and	and	CC
cord-322166-ajolu2rh	130	27	lungs	lung	NNS
cord-322166-ajolu2rh	130	28	of	of	IN
cord-322166-ajolu2rh	130	29	cynomolgus	cynomolgus	JJ
cord-322166-ajolu2rh	130	30	macaques	macaque	NNS
cord-322166-ajolu2rh	130	31	(	(	-LRB-
cord-322166-ajolu2rh	130	32	Rimmelzwaan	Rimmelzwaan	NNP
cord-322166-ajolu2rh	130	33	G	G	NNP
cord-322166-ajolu2rh	130	34	F	F	NNP
cord-322166-ajolu2rh	130	35	,	,	,
cord-322166-ajolu2rh	130	36	et	et	NNP
cord-322166-ajolu2rh	130	37	al	al	NNP
cord-322166-ajolu2rh	130	38	.	.	NNP
cord-322166-ajolu2rh	130	39	,	,	,
cord-322166-ajolu2rh	130	40	2001	2001	CD
cord-322166-ajolu2rh	130	41	)	)	-RRB-
cord-322166-ajolu2rh	130	42	.	.	.
cord-322166-ajolu2rh	131	1	In	in	IN
cord-322166-ajolu2rh	131	2	humans	human	NNS
cord-322166-ajolu2rh	131	3	,	,	,
cord-322166-ajolu2rh	131	4	the	the	DT
cord-322166-ajolu2rh	131	5	clinical	clinical	JJ
cord-322166-ajolu2rh	131	6	spectrum	spectrum	NN
cord-322166-ajolu2rh	131	7	of	of	IN
cord-322166-ajolu2rh	131	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	131	9	infection	infection	NN
cord-322166-ajolu2rh	131	10	ranges	range	VBZ
cord-322166-ajolu2rh	131	11	from	from	IN
cord-322166-ajolu2rh	131	12	asymptomatic	asymptomatic	JJ
cord-322166-ajolu2rh	131	13	to	to	IN
cord-322166-ajolu2rh	131	14	severe	severe	JJ
cord-322166-ajolu2rh	131	15	or	or	CC
cord-322166-ajolu2rh	131	16	fatal	fatal	JJ
cord-322166-ajolu2rh	131	17	disease	disease	NN
cord-322166-ajolu2rh	131	18	.	.	.
cord-322166-ajolu2rh	132	1	Despite	despite	IN
cord-322166-ajolu2rh	132	2	some	some	DT
cord-322166-ajolu2rh	132	3	features	feature	NNS
cord-322166-ajolu2rh	132	4	shared	share	VBN
cord-322166-ajolu2rh	132	5	with	with	IN
cord-322166-ajolu2rh	132	6	seasonal	seasonal	JJ
cord-322166-ajolu2rh	132	7	influenza	influenza	NN
cord-322166-ajolu2rh	132	8	viruses	virus	NNS
cord-322166-ajolu2rh	132	9	,	,	,
cord-322166-ajolu2rh	132	10	such	such	JJ
cord-322166-ajolu2rh	132	11	as	as	IN
cord-322166-ajolu2rh	132	12	high	high	JJ
cord-322166-ajolu2rh	132	13	fever	fever	NN
cord-322166-ajolu2rh	132	14	(	(	-LRB-
cord-322166-ajolu2rh	132	15	>	>	NFP
cord-322166-ajolu2rh	132	16	38	38	CD
cord-322166-ajolu2rh	132	17	°	°	NN
cord-322166-ajolu2rh	132	18	C	C	NNP
cord-322166-ajolu2rh	132	19	)	)	-RRB-
cord-322166-ajolu2rh	132	20	,	,	,
cord-322166-ajolu2rh	132	21	headache	headache	NN
cord-322166-ajolu2rh	132	22	,	,	,
cord-322166-ajolu2rh	132	23	myalgia	myalgia	NN
cord-322166-ajolu2rh	132	24	,	,	,
cord-322166-ajolu2rh	132	25	and	and	CC
cord-322166-ajolu2rh	132	26	cough	cough	NN
cord-322166-ajolu2rh	132	27	,	,	,
cord-322166-ajolu2rh	132	28	a	a	DT
cord-322166-ajolu2rh	132	29	large	large	JJ
cord-322166-ajolu2rh	132	30	number	number	NN
cord-322166-ajolu2rh	132	31	of	of	IN
cord-322166-ajolu2rh	132	32	patients	patient	NNS
cord-322166-ajolu2rh	132	33	also	also	RB
cord-322166-ajolu2rh	132	34	have	have	VBP
cord-322166-ajolu2rh	132	35	severe	severe	JJ
cord-322166-ajolu2rh	132	36	respiratory	respiratory	JJ
cord-322166-ajolu2rh	132	37	involvement	involvement	NN
cord-322166-ajolu2rh	132	38	including	include	VBG
cord-322166-ajolu2rh	132	39	dyspnea	dyspnea	NN
cord-322166-ajolu2rh	132	40	and	and	CC
cord-322166-ajolu2rh	132	41	pneumonia	pneumonia	NN
cord-322166-ajolu2rh	132	42	,	,	,
cord-322166-ajolu2rh	132	43	as	as	RB
cord-322166-ajolu2rh	132	44	well	well	RB
cord-322166-ajolu2rh	132	45	as	as	IN
cord-322166-ajolu2rh	132	46	manifestations	manifestation	NNS
cord-322166-ajolu2rh	132	47	of	of	IN
cord-322166-ajolu2rh	132	48	acute	acute	JJ
cord-322166-ajolu2rh	132	49	respiratory	respiratory	JJ
cord-322166-ajolu2rh	132	50	distress	distress	NN
cord-322166-ajolu2rh	132	51	syndrome	syndrome	NN
cord-322166-ajolu2rh	132	52	(	(	-LRB-
cord-322166-ajolu2rh	132	53	Beigel	Beigel	NNP
cord-322166-ajolu2rh	132	54	J	J	NNP
cord-322166-ajolu2rh	132	55	H	H	NNP
cord-322166-ajolu2rh	132	56	,	,	,
cord-322166-ajolu2rh	132	57	et	et	NNP
cord-322166-ajolu2rh	132	58	al	al	NNP
cord-322166-ajolu2rh	132	59	.	.	NNP
cord-322166-ajolu2rh	132	60	,	,	,
cord-322166-ajolu2rh	132	61	2005	2005	CD
cord-322166-ajolu2rh	132	62	;	;	:
cord-322166-ajolu2rh	132	63	Cameron	Cameron	NNP
cord-322166-ajolu2rh	132	64	M	M	NNP
cord-322166-ajolu2rh	132	65	J	J	NNP
cord-322166-ajolu2rh	132	66	,	,	,
cord-322166-ajolu2rh	132	67	et	et	NNP
cord-322166-ajolu2rh	132	68	al	al	NNP
cord-322166-ajolu2rh	132	69	.	.	NNP
cord-322166-ajolu2rh	132	70	;	;	:
cord-322166-ajolu2rh	132	71	Hui	Hui	NNP
cord-322166-ajolu2rh	132	72	D	D	NNP
cord-322166-ajolu2rh	132	73	S	S	NNP
cord-322166-ajolu2rh	132	74	,	,	,
cord-322166-ajolu2rh	132	75	2008	2008	CD
cord-322166-ajolu2rh	132	76	)	)	-RRB-
cord-322166-ajolu2rh	132	77	.	.	.
cord-322166-ajolu2rh	133	1	Hospital	hospital	NN
cord-322166-ajolu2rh	133	2	records	record	NNS
cord-322166-ajolu2rh	133	3	indicate	indicate	VBP
cord-322166-ajolu2rh	133	4	that	that	IN
cord-322166-ajolu2rh	133	5	rather	rather	RB
cord-322166-ajolu2rh	133	6	than	than	IN
cord-322166-ajolu2rh	133	7	upper	upper	JJ
cord-322166-ajolu2rh	133	8	respiratory	respiratory	JJ
cord-322166-ajolu2rh	133	9	tract	tract	NN
cord-322166-ajolu2rh	133	10	symptoms	symptom	NNS
cord-322166-ajolu2rh	133	11	,	,	,
cord-322166-ajolu2rh	133	12	patients	patient	NNS
cord-322166-ajolu2rh	133	13	with	with	IN
cord-322166-ajolu2rh	133	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	133	15	are	be	VBP
cord-322166-ajolu2rh	133	16	more	more	RBR
cord-322166-ajolu2rh	133	17	likely	likely	JJ
cord-322166-ajolu2rh	133	18	to	to	TO
cord-322166-ajolu2rh	133	19	develop	develop	VB
cord-322166-ajolu2rh	133	20	lower	low	JJR
cord-322166-ajolu2rh	133	21	respiratory	respiratory	JJ
cord-322166-ajolu2rh	133	22	tract	tract	NN
cord-322166-ajolu2rh	133	23	symptoms	symptom	NNS
cord-322166-ajolu2rh	133	24	within	within	IN
cord-322166-ajolu2rh	133	25	days	day	NNS
cord-322166-ajolu2rh	133	26	of	of	IN
cord-322166-ajolu2rh	133	27	admission	admission	NN
cord-322166-ajolu2rh	133	28	(	(	-LRB-
cord-322166-ajolu2rh	133	29	Hui	Hui	NNP
cord-322166-ajolu2rh	133	30	D	D	NNP
cord-322166-ajolu2rh	133	31	S	S	NNP
cord-322166-ajolu2rh	133	32	,	,	,
cord-322166-ajolu2rh	133	33	2008	2008	CD
cord-322166-ajolu2rh	133	34	)	)	-RRB-
cord-322166-ajolu2rh	133	35	.	.	.
cord-322166-ajolu2rh	134	1	Respiratory	respiratory	JJ
cord-322166-ajolu2rh	134	2	epithelial	epithelial	JJ
cord-322166-ajolu2rh	134	3	cells	cell	NNS
cord-322166-ajolu2rh	134	4	,	,	,
cord-322166-ajolu2rh	134	5	especially	especially	RB
cord-322166-ajolu2rh	134	6	the	the	DT
cord-322166-ajolu2rh	134	7	type	type	NN
cord-322166-ajolu2rh	134	8	II	II	NNP
cord-322166-ajolu2rh	134	9	pneumocytes	pneumocyte	NNS
cord-322166-ajolu2rh	134	10	,	,	,
cord-322166-ajolu2rh	134	11	are	be	VBP
cord-322166-ajolu2rh	134	12	key	key	JJ
cord-322166-ajolu2rh	134	13	target	target	NN
cord-322166-ajolu2rh	134	14	cells	cell	NNS
cord-322166-ajolu2rh	134	15	of	of	IN
cord-322166-ajolu2rh	134	16	the	the	DT
cord-322166-ajolu2rh	134	17	AIV	AIV	NNP
cord-322166-ajolu2rh	134	18	in	in	IN
cord-322166-ajolu2rh	134	19	the	the	DT
cord-322166-ajolu2rh	134	20	human	human	JJ
cord-322166-ajolu2rh	134	21	lung	lung	NN
cord-322166-ajolu2rh	134	22	in	in	IN
cord-322166-ajolu2rh	134	23	humans	human	NNS
cord-322166-ajolu2rh	134	24	,	,	,
cord-322166-ajolu2rh	134	25	and	and	CC
cord-322166-ajolu2rh	134	26	respond	respond	VB
cord-322166-ajolu2rh	134	27	by	by	IN
cord-322166-ajolu2rh	134	28	abundant	abundant	JJ
cord-322166-ajolu2rh	134	29	release	release	NN
cord-322166-ajolu2rh	134	30	of	of	IN
cord-322166-ajolu2rh	134	31	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	134	32	chemokines	chemokine	NNS
cord-322166-ajolu2rh	134	33	and	and	CC
cord-322166-ajolu2rh	134	34	cytokines	cytokine	NNS
cord-322166-ajolu2rh	134	35	(	(	-LRB-
cord-322166-ajolu2rh	134	36	Chan	Chan	NNP
cord-322166-ajolu2rh	134	37	R	R	NNP
cord-322166-ajolu2rh	134	38	W	W	NNP
cord-322166-ajolu2rh	134	39	,	,	,
cord-322166-ajolu2rh	134	40	et	et	NNP
cord-322166-ajolu2rh	134	41	al	al	NNP
cord-322166-ajolu2rh	134	42	.	.	NNP
cord-322166-ajolu2rh	134	43	,	,	,
cord-322166-ajolu2rh	134	44	2010	2010	CD
cord-322166-ajolu2rh	134	45	;	;	:
cord-322166-ajolu2rh	134	46	Peiris	Peiris	NNP
cord-322166-ajolu2rh	134	47	J	J	NNP
cord-322166-ajolu2rh	134	48	S	S	NNP
cord-322166-ajolu2rh	134	49	,	,	,
cord-322166-ajolu2rh	134	50	et	et	NNP
cord-322166-ajolu2rh	134	51	al	al	NNP
cord-322166-ajolu2rh	134	52	.	.	NNP
cord-322166-ajolu2rh	134	53	,	,	,
cord-322166-ajolu2rh	134	54	2010	2010	CD
cord-322166-ajolu2rh	134	55	;	;	:
cord-322166-ajolu2rh	134	56	Snelgrove	Snelgrove	NNP
cord-322166-ajolu2rh	134	57	R	R	NNP
cord-322166-ajolu2rh	134	58	J	J	NNP
cord-322166-ajolu2rh	134	59	,	,	,
cord-322166-ajolu2rh	134	60	et	et	NNP
cord-322166-ajolu2rh	134	61	al	al	NNP
cord-322166-ajolu2rh	134	62	.	.	NNP
cord-322166-ajolu2rh	134	63	,	,	,
cord-322166-ajolu2rh	134	64	2011	2011	CD
cord-322166-ajolu2rh	134	65	;	;	:
cord-322166-ajolu2rh	134	66	Wang	Wang	NNP
cord-322166-ajolu2rh	134	67	J	J	NNP
cord-322166-ajolu2rh	134	68	,	,	,
cord-322166-ajolu2rh	134	69	et	et	NNP
cord-322166-ajolu2rh	134	70	al	al	NNP
cord-322166-ajolu2rh	134	71	.	.	NNP
cord-322166-ajolu2rh	134	72	,	,	,
cord-322166-ajolu2rh	134	73	2009	2009	CD
cord-322166-ajolu2rh	134	74	;	;	:
cord-322166-ajolu2rh	134	75	Yu	Yu	NNP
cord-322166-ajolu2rh	134	76	W	W	NNP
cord-322166-ajolu2rh	134	77	C	C	NNP
cord-322166-ajolu2rh	134	78	,	,	,
cord-322166-ajolu2rh	134	79	et	et	NNP
cord-322166-ajolu2rh	134	80	al	al	NNP
cord-322166-ajolu2rh	134	81	.	.	NNP
cord-322166-ajolu2rh	134	82	,	,	,
cord-322166-ajolu2rh	134	83	2011	2011	CD
cord-322166-ajolu2rh	134	84	)	)	-RRB-
cord-322166-ajolu2rh	134	85	.	.	.
cord-322166-ajolu2rh	135	1	A	a	DT
cord-322166-ajolu2rh	135	2	similar	similar	JJ
cord-322166-ajolu2rh	135	3	preference	preference	NN
cord-322166-ajolu2rh	135	4	for	for	IN
cord-322166-ajolu2rh	135	5	type	type	NN
cord-322166-ajolu2rh	135	6	II	II	NNP
cord-322166-ajolu2rh	135	7	pneumocytes	pneumocytes	NNPS
cord-322166-ajolu2rh	135	8	was	be	VBD
cord-322166-ajolu2rh	135	9	observed	observe	VBN
cord-322166-ajolu2rh	135	10	in	in	IN
cord-322166-ajolu2rh	135	11	animal	animal	NN
cord-322166-ajolu2rh	135	12	models	model	NNS
cord-322166-ajolu2rh	135	13	,	,	,
cord-322166-ajolu2rh	135	14	including	include	VBG
cord-322166-ajolu2rh	135	15	the	the	DT
cord-322166-ajolu2rh	135	16	cat	cat	NN
cord-322166-ajolu2rh	135	17	,	,	,
cord-322166-ajolu2rh	135	18	mouse	mouse	NN
cord-322166-ajolu2rh	135	19	,	,	,
cord-322166-ajolu2rh	135	20	and	and	CC
cord-322166-ajolu2rh	135	21	ferret	ferret	FW
cord-322166-ajolu2rh	135	22	(	(	-LRB-
cord-322166-ajolu2rh	135	23	van	van	NNP
cord-322166-ajolu2rh	135	24	Riel	Riel	NNP
cord-322166-ajolu2rh	135	25	D	D	NNP
cord-322166-ajolu2rh	135	26	,	,	,
cord-322166-ajolu2rh	135	27	et	et	NNP
cord-322166-ajolu2rh	135	28	al	al	NNP
cord-322166-ajolu2rh	135	29	.	.	NNP
cord-322166-ajolu2rh	135	30	,	,	,
cord-322166-ajolu2rh	135	31	2006	2006	CD
cord-322166-ajolu2rh	135	32	)	)	-RRB-
cord-322166-ajolu2rh	135	33	.	.	.
cord-322166-ajolu2rh	136	1	Alveolar	alveolar	NN
cord-322166-ajolu2rh	136	2	epithelium	epithelium	NN
cord-322166-ajolu2rh	136	3	cells	cell	NNS
cord-322166-ajolu2rh	136	4	amplify	amplify	VBP
cord-322166-ajolu2rh	136	5	the	the	DT
cord-322166-ajolu2rh	136	6	H5N1	H5N1	NNP
cord-322166-ajolu2rh	136	7	virus	virus	NN
cord-322166-ajolu2rh	136	8	-	-	HYPH
cord-322166-ajolu2rh	136	9	induced	induce	VBN
cord-322166-ajolu2rh	136	10	cytokine	cytokine	NN
cord-322166-ajolu2rh	136	11	cascade	cascade	NN
cord-322166-ajolu2rh	136	12	,	,	,
cord-322166-ajolu2rh	136	13	which	which	WDT
cord-322166-ajolu2rh	136	14	is	be	VBZ
cord-322166-ajolu2rh	136	15	an	an	DT
cord-322166-ajolu2rh	136	16	important	important	JJ
cord-322166-ajolu2rh	136	17	component	component	NN
cord-322166-ajolu2rh	136	18	of	of	IN
cord-322166-ajolu2rh	136	19	H5N1	H5N1	NNP
cord-322166-ajolu2rh	136	20	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	136	21	(	(	-LRB-
cord-322166-ajolu2rh	136	22	Snelgrove	Snelgrove	NNP
cord-322166-ajolu2rh	136	23	R	R	NNP
cord-322166-ajolu2rh	136	24	J	J	NNP
cord-322166-ajolu2rh	136	25	,	,	,
cord-322166-ajolu2rh	136	26	et	et	NNP
cord-322166-ajolu2rh	136	27	al	al	NNP
cord-322166-ajolu2rh	136	28	.	.	NNP
cord-322166-ajolu2rh	136	29	,	,	,
cord-322166-ajolu2rh	136	30	2011	2011	CD
cord-322166-ajolu2rh	136	31	)	)	-RRB-
cord-322166-ajolu2rh	136	32	.	.	.
cord-322166-ajolu2rh	137	1	One	one	CD
cord-322166-ajolu2rh	137	2	of	of	IN
cord-322166-ajolu2rh	137	3	the	the	DT
cord-322166-ajolu2rh	137	4	primary	primary	JJ
cord-322166-ajolu2rh	137	5	clinical	clinical	JJ
cord-322166-ajolu2rh	137	6	outcomes	outcome	NNS
cord-322166-ajolu2rh	137	7	is	be	VBZ
cord-322166-ajolu2rh	137	8	acute	acute	JJ
cord-322166-ajolu2rh	137	9	lung	lung	NN
cord-322166-ajolu2rh	137	10	injury	injury	NN
cord-322166-ajolu2rh	137	11	(	(	-LRB-
cord-322166-ajolu2rh	137	12	ALI	ALI	NNP
cord-322166-ajolu2rh	137	13	)	)	-RRB-
cord-322166-ajolu2rh	137	14	,	,	,
cord-322166-ajolu2rh	137	15	presumed	presume	VBN
cord-322166-ajolu2rh	137	16	to	to	TO
cord-322166-ajolu2rh	137	17	be	be	VB
cord-322166-ajolu2rh	137	18	a	a	DT
cord-322166-ajolu2rh	137	19	consequence	consequence	NN
cord-322166-ajolu2rh	137	20	of	of	IN
cord-322166-ajolu2rh	137	21	autophagic	autophagic	JJ
cord-322166-ajolu2rh	137	22	cell	cell	NN
cord-322166-ajolu2rh	137	23	death	death	NN
cord-322166-ajolu2rh	137	24	within	within	IN
cord-322166-ajolu2rh	137	25	the	the	DT
cord-322166-ajolu2rh	137	26	alveolar	alveolar	JJ
cord-322166-ajolu2rh	137	27	epithelium	epithelium	NN
cord-322166-ajolu2rh	137	28	.	.	.
cord-322166-ajolu2rh	138	1	Severe	severe	JJ
cord-322166-ajolu2rh	138	2	ALI	ALI	NNP
cord-322166-ajolu2rh	138	3	appears	appear	VBZ
cord-322166-ajolu2rh	138	4	to	to	TO
cord-322166-ajolu2rh	138	5	be	be	VB
cord-322166-ajolu2rh	138	6	major	major	JJ
cord-322166-ajolu2rh	138	7	cause	cause	NN
cord-322166-ajolu2rh	138	8	of	of	IN
cord-322166-ajolu2rh	138	9	fatality	fatality	NN
cord-322166-ajolu2rh	138	10	(	(	-LRB-
cord-322166-ajolu2rh	138	11	Sun	Sun	NNP
cord-322166-ajolu2rh	138	12	Y	Y	NNP
cord-322166-ajolu2rh	138	13	,	,	,
cord-322166-ajolu2rh	138	14	et	et	NNP
cord-322166-ajolu2rh	138	15	al	al	NNP
cord-322166-ajolu2rh	138	16	.	.	NNP
cord-322166-ajolu2rh	138	17	,	,	,
cord-322166-ajolu2rh	138	18	2012	2012	CD
cord-322166-ajolu2rh	138	19	;	;	:
cord-322166-ajolu2rh	138	20	WHO	who	WP
cord-322166-ajolu2rh	138	21	,	,	,
cord-322166-ajolu2rh	138	22	2008	2008	CD
cord-322166-ajolu2rh	138	23	)	)	-RRB-
cord-322166-ajolu2rh	138	24	.	.	.
cord-322166-ajolu2rh	139	1	Numerous	numerous	JJ
cord-322166-ajolu2rh	139	2	studies	study	NNS
cord-322166-ajolu2rh	139	3	indicate	indicate	VBP
cord-322166-ajolu2rh	139	4	that	that	IN
cord-322166-ajolu2rh	139	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	139	6	is	be	VBZ
cord-322166-ajolu2rh	139	7	more	more	RBR
cord-322166-ajolu2rh	139	8	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	139	9	than	than	IN
cord-322166-ajolu2rh	139	10	seasonal	seasonal	JJ
cord-322166-ajolu2rh	139	11	influenza	influenza	NN
cord-322166-ajolu2rh	139	12	.	.	.
cord-322166-ajolu2rh	140	1	Tests	test	NNS
cord-322166-ajolu2rh	140	2	in	in	IN
cord-322166-ajolu2rh	140	3	mice	mouse	NNS
cord-322166-ajolu2rh	140	4	and	and	CC
cord-322166-ajolu2rh	140	5	primates	primate	NNS
cord-322166-ajolu2rh	140	6	showed	show	VBD
cord-322166-ajolu2rh	140	7	more	more	RBR
cord-322166-ajolu2rh	140	8	severe	severe	JJ
cord-322166-ajolu2rh	140	9	lung	lung	NN
cord-322166-ajolu2rh	140	10	inflammation	inflammation	NN
cord-322166-ajolu2rh	140	11	and	and	CC
cord-322166-ajolu2rh	140	12	higher	high	JJR
cord-322166-ajolu2rh	140	13	virus	virus	NN
cord-322166-ajolu2rh	140	14	yields	yield	NNS
cord-322166-ajolu2rh	140	15	following	follow	VBG
cord-322166-ajolu2rh	140	16	infection	infection	NN
cord-322166-ajolu2rh	140	17	with	with	IN
cord-322166-ajolu2rh	140	18	the	the	DT
cord-322166-ajolu2rh	140	19	H5N1	H5N1	NNP
cord-322166-ajolu2rh	140	20	virus	virus	NN
cord-322166-ajolu2rh	140	21	than	than	IN
cord-322166-ajolu2rh	140	22	with	with	IN
cord-322166-ajolu2rh	140	23	seasonal	seasonal	JJ
cord-322166-ajolu2rh	140	24	virus	virus	NN
cord-322166-ajolu2rh	140	25	,	,	,
cord-322166-ajolu2rh	140	26	or	or	CC
cord-322166-ajolu2rh	140	27	a	a	DT
cord-322166-ajolu2rh	140	28	reassortant	reassortant	JJ
cord-322166-ajolu2rh	140	29	1918	1918	CD
cord-322166-ajolu2rh	140	30	H1N1	H1N1	NNP
cord-322166-ajolu2rh	140	31	virus	virus	NN
cord-322166-ajolu2rh	140	32	(	(	-LRB-
cord-322166-ajolu2rh	140	33	Baskin	Baskin	NNP
cord-322166-ajolu2rh	140	34	C	C	NNP
cord-322166-ajolu2rh	140	35	R	R	NNP
cord-322166-ajolu2rh	140	36	,	,	,
cord-322166-ajolu2rh	140	37	et	et	NNP
cord-322166-ajolu2rh	140	38	al	al	NNP
cord-322166-ajolu2rh	140	39	.	.	NNP
cord-322166-ajolu2rh	140	40	,	,	,
cord-322166-ajolu2rh	140	41	2009	2009	CD
cord-322166-ajolu2rh	140	42	;	;	:
cord-322166-ajolu2rh	140	43	Sun	Sun	NNP
cord-322166-ajolu2rh	140	44	Y	Y	NNP
cord-322166-ajolu2rh	140	45	,	,	,
cord-322166-ajolu2rh	140	46	et	et	NNP
cord-322166-ajolu2rh	140	47	al	al	NNP
cord-322166-ajolu2rh	140	48	.	.	NNP
cord-322166-ajolu2rh	140	49	,	,	,
cord-322166-ajolu2rh	140	50	2012	2012	CD
cord-322166-ajolu2rh	140	51	)	)	-RRB-
cord-322166-ajolu2rh	140	52	.	.	.
cord-322166-ajolu2rh	141	1	However	however	RB
cord-322166-ajolu2rh	141	2	,	,	,
cord-322166-ajolu2rh	141	3	similar	similar	JJ
cord-322166-ajolu2rh	141	4	levels	level	NNS
cord-322166-ajolu2rh	141	5	of	of	IN
cord-322166-ajolu2rh	141	6	apoptosis	apoptosis	NN
cord-322166-ajolu2rh	141	7	were	be	VBD
cord-322166-ajolu2rh	141	8	seen	see	VBN
cord-322166-ajolu2rh	141	9	in	in	IN
cord-322166-ajolu2rh	141	10	A549	a549	JJ
cord-322166-ajolu2rh	141	11	cells	cell	NNS
cord-322166-ajolu2rh	141	12	,	,	,
cord-322166-ajolu2rh	141	13	with	with	IN
cord-322166-ajolu2rh	141	14	undetectable	undetectable	JJ
cord-322166-ajolu2rh	141	15	differences	difference	NNS
cord-322166-ajolu2rh	141	16	in	in	IN
cord-322166-ajolu2rh	141	17	virus	virus	NN
cord-322166-ajolu2rh	141	18	yield	yield	NN
cord-322166-ajolu2rh	141	19	,	,	,
cord-322166-ajolu2rh	141	20	indicating	indicate	VBG
cord-322166-ajolu2rh	141	21	that	that	IN
cord-322166-ajolu2rh	141	22	higher	high	JJR
cord-322166-ajolu2rh	141	23	virus	virus	NN
cord-322166-ajolu2rh	141	24	load	load	NN
cord-322166-ajolu2rh	141	25	does	do	VBZ
cord-322166-ajolu2rh	141	26	not	not	RB
cord-322166-ajolu2rh	141	27	necessarily	necessarily	RB
cord-322166-ajolu2rh	141	28	result	result	VB
cord-322166-ajolu2rh	141	29	in	in	IN
cord-322166-ajolu2rh	141	30	more	more	JJR
cord-322166-ajolu2rh	141	31	severe	severe	JJ
cord-322166-ajolu2rh	141	32	disease	disease	NN
cord-322166-ajolu2rh	141	33	(	(	-LRB-
cord-322166-ajolu2rh	141	34	Sun	Sun	NNP
cord-322166-ajolu2rh	141	35	Y	Y	NNP
cord-322166-ajolu2rh	141	36	,	,	,
cord-322166-ajolu2rh	141	37	et	et	NNP
cord-322166-ajolu2rh	141	38	al	al	NNP
cord-322166-ajolu2rh	141	39	.	.	NNP
cord-322166-ajolu2rh	141	40	,	,	,
cord-322166-ajolu2rh	141	41	2012	2012	CD
cord-322166-ajolu2rh	141	42	)	)	-RRB-
cord-322166-ajolu2rh	141	43	.	.	.
cord-322166-ajolu2rh	142	1	Chest	chest	NN
cord-322166-ajolu2rh	142	2	radiographs	radiograph	NNS
cord-322166-ajolu2rh	142	3	revealed	reveal	VBD
cord-322166-ajolu2rh	142	4	that	that	IN
cord-322166-ajolu2rh	142	5	although	although	IN
cord-322166-ajolu2rh	142	6	multifocal	multifocal	JJ
cord-322166-ajolu2rh	142	7	broncho	broncho	JJ
cord-322166-ajolu2rh	142	8	-	-	HYPH
cord-322166-ajolu2rh	142	9	pneumonia	pneumonia	NN
cord-322166-ajolu2rh	142	10	in	in	IN
cord-322166-ajolu2rh	142	11	the	the	DT
cord-322166-ajolu2rh	142	12	parahilar	parahilar	NN
cord-322166-ajolu2rh	142	13	of	of	IN
cord-322166-ajolu2rh	142	14	both	both	DT
cord-322166-ajolu2rh	142	15	lungs	lung	NNS
cord-322166-ajolu2rh	142	16	can	can	MD
cord-322166-ajolu2rh	142	17	been	be	VBN
cord-322166-ajolu2rh	142	18	seen	see	VBN
cord-322166-ajolu2rh	142	19	predominantly	predominantly	RB
cord-322166-ajolu2rh	142	20	when	when	WRB
cord-322166-ajolu2rh	142	21	infected	infect	VBN
cord-322166-ajolu2rh	142	22	with	with	IN
cord-322166-ajolu2rh	142	23	pneumococcus	pneumococcus	NN
cord-322166-ajolu2rh	142	24	,	,	,
cord-322166-ajolu2rh	142	25	H5N1	H5N1	NNP
cord-322166-ajolu2rh	142	26	pneumonia	pneumonia	NN
cord-322166-ajolu2rh	142	27	presented	present	VBN
cord-322166-ajolu2rh	142	28	with	with	IN
cord-322166-ajolu2rh	142	29	bilateral	bilateral	JJ
cord-322166-ajolu2rh	142	30	interstitial	interstitial	JJ
cord-322166-ajolu2rh	142	31	infiltration	infiltration	NN
cord-322166-ajolu2rh	142	32	(	(	-LRB-
cord-322166-ajolu2rh	142	33	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	142	34	M	M	NNP
cord-322166-ajolu2rh	142	35	J	J	NNP
cord-322166-ajolu2rh	142	36	,	,	,
cord-322166-ajolu2rh	142	37	2010	2010	CD
cord-322166-ajolu2rh	142	38	)	)	-RRB-
cord-322166-ajolu2rh	142	39	.	.	.
cord-322166-ajolu2rh	143	1	Central	central	JJ
cord-322166-ajolu2rh	143	2	nervous	nervous	JJ
cord-322166-ajolu2rh	143	3	system	system	NN
cord-322166-ajolu2rh	143	4	(	(	-LRB-
cord-322166-ajolu2rh	143	5	CNS	CNS	NNP
cord-322166-ajolu2rh	143	6	)	)	-RRB-
cord-322166-ajolu2rh	143	7	manifestations	manifestation	NNS
cord-322166-ajolu2rh	143	8	are	be	VBP
cord-322166-ajolu2rh	143	9	infrequent	infrequent	JJ
cord-322166-ajolu2rh	143	10	with	with	IN
cord-322166-ajolu2rh	143	11	seasonal	seasonal	JJ
cord-322166-ajolu2rh	143	12	influenza	influenza	NN
cord-322166-ajolu2rh	143	13	virus	virus	NN
cord-322166-ajolu2rh	143	14	,	,	,
cord-322166-ajolu2rh	143	15	but	but	CC
cord-322166-ajolu2rh	143	16	been	be	VBN
cord-322166-ajolu2rh	143	17	observed	observe	VBN
cord-322166-ajolu2rh	143	18	in	in	IN
cord-322166-ajolu2rh	143	19	H5N1-virus	H5N1-virus	NNP
cord-322166-ajolu2rh	143	20	-	-	HYPH
cord-322166-ajolu2rh	143	21	infected	infect	VBN
cord-322166-ajolu2rh	143	22	patients	patient	NNS
cord-322166-ajolu2rh	143	23	(	(	-LRB-
cord-322166-ajolu2rh	143	24	de	de	FW
cord-322166-ajolu2rh	143	25	Jong	Jong	NNP
cord-322166-ajolu2rh	143	26	M	M	NNP
cord-322166-ajolu2rh	143	27	D	D	NNP
cord-322166-ajolu2rh	143	28	,	,	,
cord-322166-ajolu2rh	143	29	et	et	NNP
cord-322166-ajolu2rh	143	30	al	al	NNP
cord-322166-ajolu2rh	143	31	.	.	NNP
cord-322166-ajolu2rh	143	32	,	,	,
cord-322166-ajolu2rh	143	33	2005	2005	CD
cord-322166-ajolu2rh	143	34	)	)	-RRB-
cord-322166-ajolu2rh	143	35	.	.	.
cord-322166-ajolu2rh	144	1	Other	other	JJ
cord-322166-ajolu2rh	144	2	studies	study	NNS
cord-322166-ajolu2rh	144	3	showed	show	VBD
cord-322166-ajolu2rh	144	4	that	that	IN
cord-322166-ajolu2rh	144	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	144	6	infection	infection	NN
cord-322166-ajolu2rh	144	7	of	of	IN
cord-322166-ajolu2rh	144	8	the	the	DT
cord-322166-ajolu2rh	144	9	CNS	CNS	NNP
cord-322166-ajolu2rh	144	10	can	can	MD
cord-322166-ajolu2rh	144	11	induce	induce	VB
cord-322166-ajolu2rh	144	12	Parkinsonian	Parkinsonian	NNP
cord-322166-ajolu2rh	144	13	symptoms	symptom	NNS
cord-322166-ajolu2rh	144	14	as	as	RB
cord-322166-ajolu2rh	144	15	well	well	RB
cord-322166-ajolu2rh	144	16	as	as	IN
cord-322166-ajolu2rh	144	17	substantia	substantia	NNP
cord-322166-ajolu2rh	144	18	nigra	nigra	NNP
cord-322166-ajolu2rh	144	19	pars	pars	NNP
cord-322166-ajolu2rh	144	20	compacta	compacta	NN
cord-322166-ajolu2rh	144	21	dopaminergic	dopaminergic	JJ
cord-322166-ajolu2rh	144	22	neuron	neuron	NN
cord-322166-ajolu2rh	144	23	degeneration	degeneration	NN
cord-322166-ajolu2rh	145	1	(	(	-LRB-
cord-322166-ajolu2rh	145	2	Jang	Jang	NNP
cord-322166-ajolu2rh	145	3	H	H	NNP
cord-322166-ajolu2rh	145	4	,	,	,
cord-322166-ajolu2rh	145	5	et	et	NNP
cord-322166-ajolu2rh	145	6	al	al	NNP
cord-322166-ajolu2rh	145	7	.	.	NNP
cord-322166-ajolu2rh	145	8	,	,	,
cord-322166-ajolu2rh	145	9	2009	2009	CD
cord-322166-ajolu2rh	145	10	)	)	-RRB-
cord-322166-ajolu2rh	145	11	.	.	.
cord-322166-ajolu2rh	146	1	Animal	animal	NN
cord-322166-ajolu2rh	146	2	studies	study	NNS
cord-322166-ajolu2rh	146	3	show	show	VBP
cord-322166-ajolu2rh	146	4	a	a	DT
cord-322166-ajolu2rh	146	5	similar	similar	JJ
cord-322166-ajolu2rh	146	6	spectrum	spectrum	NN
cord-322166-ajolu2rh	146	7	of	of	IN
cord-322166-ajolu2rh	146	8	CNS	CNS	NNP
cord-322166-ajolu2rh	146	9	disease	disease	NN
cord-322166-ajolu2rh	146	10	and	and	CC
cord-322166-ajolu2rh	146	11	encephalopathy	encephalopathy	NN
cord-322166-ajolu2rh	146	12	after	after	IN
cord-322166-ajolu2rh	146	13	infection	infection	NN
cord-322166-ajolu2rh	146	14	with	with	IN
cord-322166-ajolu2rh	146	15	HPAI	HPAI	NNP
cord-322166-ajolu2rh	146	16	H5N1	H5N1	NNP
cord-322166-ajolu2rh	146	17	virus	virus	NN
cord-322166-ajolu2rh	146	18	,	,	,
cord-322166-ajolu2rh	146	19	with	with	IN
cord-322166-ajolu2rh	146	20	high	high	JJ
cord-322166-ajolu2rh	146	21	levels	level	NNS
cord-322166-ajolu2rh	146	22	of	of	IN
cord-322166-ajolu2rh	146	23	pro	pro	JJ
cord-322166-ajolu2rh	146	24	-	-	JJ
cord-322166-ajolu2rh	146	25	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	146	26	cytokines	cytokine	NNS
cord-322166-ajolu2rh	146	27	including	include	VBG
cord-322166-ajolu2rh	146	28	TNF	TNF	NNP
cord-322166-ajolu2rh	146	29	-	-	HYPH
cord-322166-ajolu2rh	146	30	α	α	NNP
cord-322166-ajolu2rh	146	31	,	,	,
cord-322166-ajolu2rh	146	32	IFNs	IFNs	NNP
cord-322166-ajolu2rh	146	33	,	,	,
cord-322166-ajolu2rh	146	34	IL-1	IL-1	NNP
cord-322166-ajolu2rh	146	35	and	and	CC
cord-322166-ajolu2rh	146	36	IL-6	IL-6	NNP
cord-322166-ajolu2rh	146	37	(	(	-LRB-
cord-322166-ajolu2rh	146	38	Thiry	Thiry	NNP
cord-322166-ajolu2rh	146	39	E	E	NNP
cord-322166-ajolu2rh	146	40	,	,	,
cord-322166-ajolu2rh	146	41	et	et	NNP
cord-322166-ajolu2rh	146	42	al	al	NNP
cord-322166-ajolu2rh	146	43	.	.	NNP
cord-322166-ajolu2rh	146	44	,	,	,
cord-322166-ajolu2rh	146	45	2007	2007	CD
cord-322166-ajolu2rh	146	46	;	;	:
cord-322166-ajolu2rh	146	47	Tolnay	Tolnay	NNP
cord-322166-ajolu2rh	146	48	A	A	NNP
cord-322166-ajolu2rh	146	49	E	e	NN
cord-322166-ajolu2rh	146	50	,	,	,
cord-322166-ajolu2rh	146	51	et	et	NNP
cord-322166-ajolu2rh	146	52	al	al	NNP
cord-322166-ajolu2rh	146	53	.	.	NNP
cord-322166-ajolu2rh	146	54	,	,	,
cord-322166-ajolu2rh	146	55	2010	2010	CD
cord-322166-ajolu2rh	146	56	)	)	-RRB-
cord-322166-ajolu2rh	146	57	.	.	.
cord-322166-ajolu2rh	147	1	In	in	IN
cord-322166-ajolu2rh	147	2	the	the	DT
cord-322166-ajolu2rh	147	3	mouse	mouse	NN
cord-322166-ajolu2rh	147	4	model	model	NN
cord-322166-ajolu2rh	147	5	,	,	,
cord-322166-ajolu2rh	147	6	fatal	fatal	JJ
cord-322166-ajolu2rh	147	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	147	8	infections	infection	NNS
cord-322166-ajolu2rh	147	9	were	be	VBD
cord-322166-ajolu2rh	147	10	associated	associate	VBN
cord-322166-ajolu2rh	147	11	with	with	IN
cord-322166-ajolu2rh	147	12	the	the	DT
cord-322166-ajolu2rh	147	13	appearance	appearance	NN
cord-322166-ajolu2rh	147	14	of	of	IN
cord-322166-ajolu2rh	147	15	CD3	CD3	NNP
cord-322166-ajolu2rh	147	16	+	+	CC
cord-322166-ajolu2rh	147	17	T	T	NNP
cord-322166-ajolu2rh	147	18	cells	cell	NNS
cord-322166-ajolu2rh	147	19	and	and	CC
cord-322166-ajolu2rh	147	20	TUNEL+	TUNEL+	NNS
cord-322166-ajolu2rh	147	21	cells	cell	NNS
cord-322166-ajolu2rh	147	22	in	in	IN
cord-322166-ajolu2rh	147	23	the	the	DT
cord-322166-ajolu2rh	147	24	CNS	CNS	NNP
cord-322166-ajolu2rh	147	25	,	,	,
cord-322166-ajolu2rh	147	26	as	as	RB
cord-322166-ajolu2rh	147	27	well	well	RB
cord-322166-ajolu2rh	147	28	as	as	IN
cord-322166-ajolu2rh	147	29	the	the	DT
cord-322166-ajolu2rh	147	30	absence	absence	NN
cord-322166-ajolu2rh	147	31	of	of	IN
cord-322166-ajolu2rh	147	32	perineuronal	perineuronal	JJ
cord-322166-ajolu2rh	147	33	nets	net	NNS
cord-322166-ajolu2rh	147	34	in	in	IN
cord-322166-ajolu2rh	147	35	the	the	DT
cord-322166-ajolu2rh	147	36	brain	brain	NN
cord-322166-ajolu2rh	147	37	(	(	-LRB-
cord-322166-ajolu2rh	147	38	Bissel	Bissel	NNP
cord-322166-ajolu2rh	147	39	S	S	NNP
cord-322166-ajolu2rh	147	40	J	J	NNP
cord-322166-ajolu2rh	147	41	,	,	,
cord-322166-ajolu2rh	147	42	et	et	NNP
cord-322166-ajolu2rh	147	43	al	al	NNP
cord-322166-ajolu2rh	147	44	.	.	NNP
cord-322166-ajolu2rh	147	45	,	,	,
cord-322166-ajolu2rh	147	46	2012	2012	CD
cord-322166-ajolu2rh	147	47	)	)	-RRB-
cord-322166-ajolu2rh	147	48	.	.	.
cord-322166-ajolu2rh	148	1	Nevertheless	nevertheless	RB
cord-322166-ajolu2rh	148	2	,	,	,
cord-322166-ajolu2rh	148	3	IFN	IFN	NNP
cord-322166-ajolu2rh	148	4	levels	level	NNS
cord-322166-ajolu2rh	148	5	,	,	,
cord-322166-ajolu2rh	148	6	especially	especially	RB
cord-322166-ajolu2rh	148	7	IFN	IFN	NNP
cord-322166-ajolu2rh	148	8	-	-	HYPH
cord-322166-ajolu2rh	148	9	γ	γ	NNP
cord-322166-ajolu2rh	148	10	,	,	,
cord-322166-ajolu2rh	148	11	were	be	VBD
cord-322166-ajolu2rh	148	12	not	not	RB
cord-322166-ajolu2rh	148	13	as	as	RB
cord-322166-ajolu2rh	148	14	high	high	JJ
cord-322166-ajolu2rh	148	15	in	in	IN
cord-322166-ajolu2rh	148	16	the	the	DT
cord-322166-ajolu2rh	148	17	CNS	CNS	NNP
cord-322166-ajolu2rh	148	18	as	as	IN
cord-322166-ajolu2rh	148	19	in	in	IN
cord-322166-ajolu2rh	148	20	the	the	DT
cord-322166-ajolu2rh	148	21	lungs	lung	NNS
cord-322166-ajolu2rh	148	22	(	(	-LRB-
cord-322166-ajolu2rh	148	23	Bissel	Bissel	NNP
cord-322166-ajolu2rh	148	24	S	S	NNP
cord-322166-ajolu2rh	148	25	J	J	NNP
cord-322166-ajolu2rh	148	26	,	,	,
cord-322166-ajolu2rh	148	27	et	et	NNP
cord-322166-ajolu2rh	148	28	al	al	NNP
cord-322166-ajolu2rh	148	29	.	.	NNP
cord-322166-ajolu2rh	148	30	,	,	,
cord-322166-ajolu2rh	148	31	2012	2012	CD
cord-322166-ajolu2rh	148	32	)	)	-RRB-
cord-322166-ajolu2rh	148	33	.	.	.
cord-322166-ajolu2rh	149	1	The	the	DT
cord-322166-ajolu2rh	149	2	mechanism	mechanism	NN
cord-322166-ajolu2rh	149	3	of	of	IN
cord-322166-ajolu2rh	149	4	H5N1	H5N1	NNP
cord-322166-ajolu2rh	149	5	access	access	NN
cord-322166-ajolu2rh	149	6	of	of	IN
cord-322166-ajolu2rh	149	7	the	the	DT
cord-322166-ajolu2rh	149	8	CNS	CNS	NNP
cord-322166-ajolu2rh	149	9	is	be	VBZ
cord-322166-ajolu2rh	149	10	not	not	RB
cord-322166-ajolu2rh	149	11	fully	fully	RB
cord-322166-ajolu2rh	149	12	understood	understand	VBN
cord-322166-ajolu2rh	149	13	,	,	,
cord-322166-ajolu2rh	149	14	but	but	CC
cord-322166-ajolu2rh	149	15	one	one	CD
cord-322166-ajolu2rh	149	16	hypothesis	hypothesis	NN
cord-322166-ajolu2rh	149	17	is	be	VBZ
cord-322166-ajolu2rh	149	18	that	that	IN
cord-322166-ajolu2rh	149	19	the	the	DT
cord-322166-ajolu2rh	149	20	E223	e223	NN
cord-322166-ajolu2rh	149	21	K	k	NN
cord-322166-ajolu2rh	149	22	mutation	mutation	NN
cord-322166-ajolu2rh	149	23	of	of	IN
cord-322166-ajolu2rh	149	24	HA	HA	NNP
cord-322166-ajolu2rh	149	25	facilitates	facilitate	VBZ
cord-322166-ajolu2rh	149	26	virus	virus	NN
cord-322166-ajolu2rh	149	27	spread	spread	VBN
cord-322166-ajolu2rh	149	28	to	to	IN
cord-322166-ajolu2rh	149	29	the	the	DT
cord-322166-ajolu2rh	149	30	brain	brain	NN
cord-322166-ajolu2rh	149	31	and	and	CC
cord-322166-ajolu2rh	149	32	binding	bind	VBG
cord-322166-ajolu2rh	149	33	to	to	IN
cord-322166-ajolu2rh	149	34	neurons	neuron	NNS
cord-322166-ajolu2rh	149	35	(	(	-LRB-
cord-322166-ajolu2rh	149	36	Manz	Manz	NNP
cord-322166-ajolu2rh	149	37	B	B	NNP
cord-322166-ajolu2rh	149	38	,	,	,
cord-322166-ajolu2rh	150	1	et	et	NNP
cord-322166-ajolu2rh	150	2	al	al	NNP
cord-322166-ajolu2rh	150	3	.	.	NNP
cord-322166-ajolu2rh	150	4	,	,	,
cord-322166-ajolu2rh	150	5	2010	2010	CD
cord-322166-ajolu2rh	150	6	)	)	-RRB-
cord-322166-ajolu2rh	150	7	.	.	.
cord-322166-ajolu2rh	151	1	In	in	IN
cord-322166-ajolu2rh	151	2	contrast	contrast	NN
cord-322166-ajolu2rh	151	3	with	with	IN
cord-322166-ajolu2rh	151	4	seasonal	seasonal	JJ
cord-322166-ajolu2rh	151	5	influenza	influenza	NN
cord-322166-ajolu2rh	151	6	strains	strain	NNS
cord-322166-ajolu2rh	151	7	,	,	,
cord-322166-ajolu2rh	151	8	a	a	DT
cord-322166-ajolu2rh	151	9	large	large	JJ
cord-322166-ajolu2rh	151	10	proportion	proportion	NN
cord-322166-ajolu2rh	151	11	of	of	IN
cord-322166-ajolu2rh	151	12	H5N1-infected	h5n1-infected	JJ
cord-322166-ajolu2rh	151	13	patients	patient	NNS
cord-322166-ajolu2rh	151	14	(	(	-LRB-
cord-322166-ajolu2rh	151	15	both	both	DT
cord-322166-ajolu2rh	151	16	children	child	NNS
cord-322166-ajolu2rh	151	17	and	and	CC
cord-322166-ajolu2rh	151	18	adults	adult	NNS
cord-322166-ajolu2rh	151	19	)	)	-RRB-
cord-322166-ajolu2rh	151	20	have	have	VBP
cord-322166-ajolu2rh	151	21	gastrointestinal	gastrointestinal	JJ
cord-322166-ajolu2rh	151	22	symptoms	symptom	NNS
cord-322166-ajolu2rh	151	23	such	such	JJ
cord-322166-ajolu2rh	151	24	as	as	IN
cord-322166-ajolu2rh	151	25	watery	watery	JJ
cord-322166-ajolu2rh	151	26	diarrhea	diarrhea	NN
cord-322166-ajolu2rh	151	27	,	,	,
cord-322166-ajolu2rh	151	28	vomiting	vomit	VBG
cord-322166-ajolu2rh	151	29	,	,	,
cord-322166-ajolu2rh	151	30	and	and	CC
cord-322166-ajolu2rh	151	31	abdominal	abdominal	JJ
cord-322166-ajolu2rh	151	32	pain	pain	NN
cord-322166-ajolu2rh	151	33	,	,	,
cord-322166-ajolu2rh	151	34	which	which	WDT
cord-322166-ajolu2rh	151	35	occur	occur	VBP
cord-322166-ajolu2rh	151	36	rarely	rarely	RB
cord-322166-ajolu2rh	151	37	in	in	IN
cord-322166-ajolu2rh	151	38	adults	adult	NNS
cord-322166-ajolu2rh	151	39	with	with	IN
cord-322166-ajolu2rh	151	40	human	human	JJ
cord-322166-ajolu2rh	151	41	seasonal	seasonal	JJ
cord-322166-ajolu2rh	151	42	influenza	influenza	NN
cord-322166-ajolu2rh	151	43	(	(	-LRB-
cord-322166-ajolu2rh	151	44	Kandun	Kandun	NNP
cord-322166-ajolu2rh	151	45	I	I	NNP
cord-322166-ajolu2rh	151	46	N	N	NNP
cord-322166-ajolu2rh	151	47	,	,	,
cord-322166-ajolu2rh	151	48	et	et	NNP
cord-322166-ajolu2rh	151	49	al	al	NNP
cord-322166-ajolu2rh	151	50	.	.	NNP
cord-322166-ajolu2rh	151	51	,	,	,
cord-322166-ajolu2rh	151	52	2008	2008	CD
cord-322166-ajolu2rh	151	53	;	;	:
cord-322166-ajolu2rh	151	54	Wang	Wang	NNP
cord-322166-ajolu2rh	151	55	H	H	NNP
cord-322166-ajolu2rh	151	56	,	,	,
cord-322166-ajolu2rh	151	57	et	et	NNP
cord-322166-ajolu2rh	151	58	al	al	NNP
cord-322166-ajolu2rh	151	59	.	.	NNP
cord-322166-ajolu2rh	151	60	,	,	,
cord-322166-ajolu2rh	151	61	2009	2009	CD
cord-322166-ajolu2rh	151	62	)	)	-RRB-
cord-322166-ajolu2rh	151	63	.	.	.
cord-322166-ajolu2rh	152	1	The	the	DT
cord-322166-ajolu2rh	152	2	relative	relative	JJ
cord-322166-ajolu2rh	152	3	increase	increase	NN
cord-322166-ajolu2rh	152	4	in	in	IN
cord-322166-ajolu2rh	152	5	frequency	frequency	NN
cord-322166-ajolu2rh	152	6	of	of	IN
cord-322166-ajolu2rh	152	7	pneumonia	pneumonia	NN
cord-322166-ajolu2rh	152	8	and	and	CC
cord-322166-ajolu2rh	152	9	gastrointestinal	gastrointestinal	JJ
cord-322166-ajolu2rh	152	10	symptoms	symptom	NNS
cord-322166-ajolu2rh	152	11	is	be	VBZ
cord-322166-ajolu2rh	152	12	an	an	DT
cord-322166-ajolu2rh	152	13	important	important	JJ
cord-322166-ajolu2rh	152	14	feature	feature	NN
cord-322166-ajolu2rh	152	15	of	of	IN
cord-322166-ajolu2rh	152	16	avian	avian	JJ
cord-322166-ajolu2rh	152	17	influenza	influenza	NN
cord-322166-ajolu2rh	152	18	,	,	,
cord-322166-ajolu2rh	152	19	and	and	CC
cord-322166-ajolu2rh	152	20	may	may	MD
cord-322166-ajolu2rh	152	21	help	help	VB
cord-322166-ajolu2rh	152	22	to	to	TO
cord-322166-ajolu2rh	152	23	distinguish	distinguish	VB
cord-322166-ajolu2rh	152	24	avian	avian	NN
cord-322166-ajolu2rh	152	25	from	from	IN
cord-322166-ajolu2rh	152	26	seasonal	seasonal	JJ
cord-322166-ajolu2rh	152	27	influenza	influenza	NN
cord-322166-ajolu2rh	152	28	in	in	IN
cord-322166-ajolu2rh	152	29	the	the	DT
cord-322166-ajolu2rh	152	30	clinic	clinic	NN
cord-322166-ajolu2rh	152	31	.	.	.
cord-322166-ajolu2rh	153	1	Multi	multi	JJ
cord-322166-ajolu2rh	153	2	-	-	JJ
cord-322166-ajolu2rh	153	3	organ	organ	NN
cord-322166-ajolu2rh	153	4	failure	failure	NN
cord-322166-ajolu2rh	153	5	involving	involve	VBG
cord-322166-ajolu2rh	153	6	the	the	DT
cord-322166-ajolu2rh	153	7	kidneys	kidney	NNS
cord-322166-ajolu2rh	153	8	,	,	,
cord-322166-ajolu2rh	153	9	liver	liver	NN
cord-322166-ajolu2rh	153	10	,	,	,
cord-322166-ajolu2rh	153	11	and	and	CC
cord-322166-ajolu2rh	153	12	many	many	JJ
cord-322166-ajolu2rh	153	13	other	other	JJ
cord-322166-ajolu2rh	153	14	non	non	JJ
cord-322166-ajolu2rh	153	15	-	-	JJ
cord-322166-ajolu2rh	153	16	respiratory	respiratory	JJ
cord-322166-ajolu2rh	153	17	organs	organ	NNS
cord-322166-ajolu2rh	153	18	has	have	VBZ
cord-322166-ajolu2rh	153	19	been	be	VBN
cord-322166-ajolu2rh	153	20	common	common	JJ
cord-322166-ajolu2rh	153	21	(	(	-LRB-
cord-322166-ajolu2rh	153	22	Thanh	Thanh	NNP
cord-322166-ajolu2rh	153	23	T	T	NNP
cord-322166-ajolu2rh	153	24	T	T	NNP
cord-322166-ajolu2rh	153	25	,	,	,
cord-322166-ajolu2rh	153	26	et	et	NNP
cord-322166-ajolu2rh	153	27	al	al	NNP
cord-322166-ajolu2rh	153	28	.	.	NNP
cord-322166-ajolu2rh	153	29	,	,	,
cord-322166-ajolu2rh	153	30	2008	2008	CD
cord-322166-ajolu2rh	153	31	)	)	-RRB-
cord-322166-ajolu2rh	153	32	.	.	.
cord-322166-ajolu2rh	154	1	Fatal	fatal	JJ
cord-322166-ajolu2rh	154	2	cases	case	NNS
cord-322166-ajolu2rh	154	3	of	of	IN
cord-322166-ajolu2rh	154	4	H5N1	H5N1	NNP
cord-322166-ajolu2rh	154	5	during	during	IN
cord-322166-ajolu2rh	154	6	pregnancy	pregnancy	NN
cord-322166-ajolu2rh	154	7	,	,	,
cord-322166-ajolu2rh	154	8	have	have	VBP
cord-322166-ajolu2rh	154	9	also	also	RB
cord-322166-ajolu2rh	154	10	been	be	VBN
cord-322166-ajolu2rh	154	11	reported	report	VBN
cord-322166-ajolu2rh	154	12	(	(	-LRB-
cord-322166-ajolu2rh	154	13	Shu	Shu	NNP
cord-322166-ajolu2rh	154	14	Y	Y	NNP
cord-322166-ajolu2rh	154	15	,	,	,
cord-322166-ajolu2rh	154	16	et	et	NNP
cord-322166-ajolu2rh	154	17	al	al	NNP
cord-322166-ajolu2rh	154	18	.	.	NNP
cord-322166-ajolu2rh	154	19	,	,	,
cord-322166-ajolu2rh	154	20	2006	2006	CD
cord-322166-ajolu2rh	154	21	)	)	-RRB-
cord-322166-ajolu2rh	154	22	.	.	.
cord-322166-ajolu2rh	155	1	Compared	compare	VBN
cord-322166-ajolu2rh	155	2	with	with	IN
cord-322166-ajolu2rh	155	3	H9	H9	NNP
cord-322166-ajolu2rh	155	4	and	and	CC
cord-322166-ajolu2rh	155	5	H7	H7	NNP
cord-322166-ajolu2rh	155	6	virus	virus	NN
cord-322166-ajolu2rh	155	7	strains	strain	NNS
cord-322166-ajolu2rh	155	8	,	,	,
cord-322166-ajolu2rh	155	9	conjunctivitis	conjunctivitis	NN
cord-322166-ajolu2rh	155	10	has	have	VBZ
cord-322166-ajolu2rh	155	11	not	not	RB
cord-322166-ajolu2rh	155	12	been	be	VBN
cord-322166-ajolu2rh	155	13	prominent	prominent	JJ
cord-322166-ajolu2rh	155	14	in	in	IN
cord-322166-ajolu2rh	155	15	H5N1-infected	h5n1-infected	JJ
cord-322166-ajolu2rh	155	16	patients	patient	NNS
cord-322166-ajolu2rh	155	17	(	(	-LRB-
cord-322166-ajolu2rh	155	18	de	de	``
cord-322166-ajolu2rh	155	19	Jong	Jong	NNP
cord-322166-ajolu2rh	155	20	M	M	NNP
cord-322166-ajolu2rh	155	21	D	D	NNP
cord-322166-ajolu2rh	155	22	,	,	,
cord-322166-ajolu2rh	155	23	et	et	NNP
cord-322166-ajolu2rh	155	24	al	al	NNP
cord-322166-ajolu2rh	155	25	.	.	NNP
cord-322166-ajolu2rh	155	26	,	,	,
cord-322166-ajolu2rh	155	27	2006	2006	CD
cord-322166-ajolu2rh	155	28	;	;	:
cord-322166-ajolu2rh	155	29	Hui	Hui	NNP
cord-322166-ajolu2rh	155	30	D	D	NNP
cord-322166-ajolu2rh	155	31	S	S	NNP
cord-322166-ajolu2rh	155	32	,	,	,
cord-322166-ajolu2rh	155	33	2008	2008	CD
cord-322166-ajolu2rh	155	34	)	)	-RRB-
cord-322166-ajolu2rh	155	35	.	.	.
cord-322166-ajolu2rh	156	1	Only	only	RB
cord-322166-ajolu2rh	156	2	rare	rare	JJ
cord-322166-ajolu2rh	156	3	H5N1	H5N1	NNP
cord-322166-ajolu2rh	156	4	cases	case	NNS
cord-322166-ajolu2rh	156	5	are	be	VBP
cord-322166-ajolu2rh	156	6	associated	associate	VBN
cord-322166-ajolu2rh	156	7	with	with	IN
cord-322166-ajolu2rh	156	8	secondary	secondary	JJ
cord-322166-ajolu2rh	156	9	bacterial	bacterial	JJ
cord-322166-ajolu2rh	156	10	infections	infection	NNS
cord-322166-ajolu2rh	156	11	,	,	,
cord-322166-ajolu2rh	156	12	which	which	WDT
cord-322166-ajolu2rh	156	13	are	be	VBP
cord-322166-ajolu2rh	156	14	commonly	commonly	RB
cord-322166-ajolu2rh	156	15	observed	observe	VBN
cord-322166-ajolu2rh	156	16	with	with	IN
cord-322166-ajolu2rh	156	17	H1N1	H1N1	NNP
cord-322166-ajolu2rh	156	18	infections	infection	NNS
cord-322166-ajolu2rh	156	19	however	however	RB
cord-322166-ajolu2rh	156	20	,	,	,
cord-322166-ajolu2rh	156	21	secondary	secondary	JJ
cord-322166-ajolu2rh	156	22	bacterial	bacterial	JJ
cord-322166-ajolu2rh	156	23	infections	infection	NNS
cord-322166-ajolu2rh	156	24	were	be	VBD
cord-322166-ajolu2rh	156	25	observed	observe	VBN
cord-322166-ajolu2rh	156	26	in	in	IN
cord-322166-ajolu2rh	156	27	H5N1	H5N1	NNP
cord-322166-ajolu2rh	156	28	cases	case	NNS
cord-322166-ajolu2rh	156	29	with	with	IN
cord-322166-ajolu2rh	156	30	hypercytokinemia	hypercytokinemia	NN
cord-322166-ajolu2rh	157	1	(	(	-LRB-
cord-322166-ajolu2rh	157	2	Gill	Gill	NNP
cord-322166-ajolu2rh	157	3	J	J	NNP
cord-322166-ajolu2rh	157	4	R	R	NNP
cord-322166-ajolu2rh	157	5	,	,	,
cord-322166-ajolu2rh	157	6	et	et	NNP
cord-322166-ajolu2rh	157	7	al	al	NNP
cord-322166-ajolu2rh	157	8	.	.	NNP
cord-322166-ajolu2rh	157	9	,	,	,
cord-322166-ajolu2rh	157	10	2010	2010	CD
cord-322166-ajolu2rh	157	11	;	;	:
cord-322166-ajolu2rh	157	12	Peiris	Peiris	NNP
cord-322166-ajolu2rh	157	13	J	J	NNP
cord-322166-ajolu2rh	157	14	S	S	NNP
cord-322166-ajolu2rh	157	15	,	,	,
cord-322166-ajolu2rh	157	16	et	et	NNP
cord-322166-ajolu2rh	157	17	al	al	NNP
cord-322166-ajolu2rh	157	18	.	.	NNP
cord-322166-ajolu2rh	157	19	,	,	,
cord-322166-ajolu2rh	157	20	2009	2009	CD
cord-322166-ajolu2rh	157	21	;	;	:
cord-322166-ajolu2rh	157	22	Peiris	Peiris	NNP
cord-322166-ajolu2rh	157	23	M	M	NNP
cord-322166-ajolu2rh	157	24	,	,	,
cord-322166-ajolu2rh	157	25	2006	2006	CD
cord-322166-ajolu2rh	157	26	)	)	-RRB-
cord-322166-ajolu2rh	157	27	.	.	.
cord-322166-ajolu2rh	158	1	Prominent	prominent	JJ
cord-322166-ajolu2rh	158	2	lymphopenia	lymphopenia	NN
cord-322166-ajolu2rh	158	3	,	,	,
cord-322166-ajolu2rh	158	4	and	and	CC
cord-322166-ajolu2rh	158	5	thrombocytopenia	thrombocytopenia	NN
cord-322166-ajolu2rh	158	6	have	have	VBP
cord-322166-ajolu2rh	158	7	also	also	RB
cord-322166-ajolu2rh	158	8	been	be	VBN
cord-322166-ajolu2rh	158	9	observed	observe	VBN
cord-322166-ajolu2rh	158	10	in	in	IN
cord-322166-ajolu2rh	158	11	H5N1-infected	h5n1-infected	JJ
cord-322166-ajolu2rh	158	12	patients	patient	NNS
cord-322166-ajolu2rh	158	13	(	(	-LRB-
cord-322166-ajolu2rh	158	14	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	158	15	M	M	NNP
cord-322166-ajolu2rh	158	16	J	J	NNP
cord-322166-ajolu2rh	158	17	,	,	,
cord-322166-ajolu2rh	158	18	2010	2010	CD
cord-322166-ajolu2rh	158	19	)	)	-RRB-
cord-322166-ajolu2rh	158	20	.	.	.
cord-322166-ajolu2rh	159	1	Laboratory	laboratory	NN
cord-322166-ajolu2rh	159	2	testing	testing	NN
cord-322166-ajolu2rh	159	3	has	have	VBZ
cord-322166-ajolu2rh	159	4	frequently	frequently	RB
cord-322166-ajolu2rh	159	5	revealed	reveal	VBN
cord-322166-ajolu2rh	159	6	8	8	CD
cord-322166-ajolu2rh	159	7	elevated	elevated	JJ
cord-322166-ajolu2rh	159	8	alanine	alanine	JJ
cord-322166-ajolu2rh	159	9	aminotransferase	aminotransferase	NN
cord-322166-ajolu2rh	159	10	,	,	,
cord-322166-ajolu2rh	159	11	aspartate	aspartate	NN
cord-322166-ajolu2rh	159	12	aminotransferase	aminotransferase	NN
cord-322166-ajolu2rh	159	13	,	,	,
cord-322166-ajolu2rh	159	14	creatinine	creatinine	NN
cord-322166-ajolu2rh	159	15	kinase	kinase	NN
cord-322166-ajolu2rh	159	16	,	,	,
cord-322166-ajolu2rh	159	17	and	and	CC
cord-322166-ajolu2rh	159	18	lactate	lactate	NN
cord-322166-ajolu2rh	159	19	dehydrogenase	dehydrogenase	NN
cord-322166-ajolu2rh	159	20	in	in	IN
cord-322166-ajolu2rh	159	21	H5N1	H5N1	NNP
cord-322166-ajolu2rh	159	22	infection	infection	NN
cord-322166-ajolu2rh	159	23	(	(	-LRB-
cord-322166-ajolu2rh	159	24	de	de	FW
cord-322166-ajolu2rh	159	25	Jong	Jong	NNP
cord-322166-ajolu2rh	159	26	M	M	NNP
cord-322166-ajolu2rh	159	27	D	D	NNP
cord-322166-ajolu2rh	159	28	,	,	,
cord-322166-ajolu2rh	159	29	et	et	NNP
cord-322166-ajolu2rh	159	30	al	al	NNP
cord-322166-ajolu2rh	159	31	.	.	NNP
cord-322166-ajolu2rh	159	32	,	,	,
cord-322166-ajolu2rh	159	33	2006	2006	CD
cord-322166-ajolu2rh	159	34	)	)	-RRB-
cord-322166-ajolu2rh	159	35	.	.	.
cord-322166-ajolu2rh	160	1	Increased	increase	VBN
cord-322166-ajolu2rh	160	2	levels	level	NNS
cord-322166-ajolu2rh	160	3	of	of	IN
cord-322166-ajolu2rh	160	4	lactate	lactate	NN
cord-322166-ajolu2rh	160	5	dehydrogenase	dehydrogenase	NN
cord-322166-ajolu2rh	160	6	and	and	CC
cord-322166-ajolu2rh	160	7	creatinine	creatinine	NN
cord-322166-ajolu2rh	160	8	phosphokinase	phosphokinase	NN
cord-322166-ajolu2rh	160	9	,	,	,
cord-322166-ajolu2rh	160	10	prolonged	prolonged	JJ
cord-322166-ajolu2rh	160	11	prothrombin	prothrombin	NN
cord-322166-ajolu2rh	160	12	time	time	NN
cord-322166-ajolu2rh	160	13	,	,	,
cord-322166-ajolu2rh	160	14	and	and	CC
cord-322166-ajolu2rh	160	15	activated	activate	VBD
cord-322166-ajolu2rh	160	16	partial	partial	JJ
cord-322166-ajolu2rh	160	17	thromboplastin	thromboplastin	NNP
cord-322166-ajolu2rh	160	18	time	time	NN
cord-322166-ajolu2rh	160	19	,	,	,
cord-322166-ajolu2rh	160	20	as	as	RB
cord-322166-ajolu2rh	160	21	well	well	RB
cord-322166-ajolu2rh	160	22	as	as	IN
cord-322166-ajolu2rh	160	23	hypo	hypo	NN
cord-322166-ajolu2rh	160	24	-	-	NN
cord-322166-ajolu2rh	160	25	albuminemia	albuminemia	JJ
cord-322166-ajolu2rh	160	26	,	,	,
cord-322166-ajolu2rh	160	27	are	be	VBP
cord-322166-ajolu2rh	160	28	also	also	RB
cord-322166-ajolu2rh	160	29	common	common	JJ
cord-322166-ajolu2rh	161	1	(	(	-LRB-
cord-322166-ajolu2rh	161	2	Hui	Hui	NNP
cord-322166-ajolu2rh	161	3	D	D	NNP
cord-322166-ajolu2rh	161	4	S	S	NNP
cord-322166-ajolu2rh	161	5	,	,	,
cord-322166-ajolu2rh	161	6	2008	2008	CD
cord-322166-ajolu2rh	161	7	)	)	-RRB-
cord-322166-ajolu2rh	161	8	.	.	.
cord-322166-ajolu2rh	162	1	In	in	IN
cord-322166-ajolu2rh	162	2	severe	severe	JJ
cord-322166-ajolu2rh	162	3	cases	case	NNS
cord-322166-ajolu2rh	162	4	,	,	,
cord-322166-ajolu2rh	162	5	insufficient	insufficient	JJ
cord-322166-ajolu2rh	162	6	expression	expression	NN
cord-322166-ajolu2rh	162	7	of	of	IN
cord-322166-ajolu2rh	162	8	perforin	perforin	NNP
cord-322166-ajolu2rh	162	9	in	in	IN
cord-322166-ajolu2rh	162	10	CD8	CD8	NNP
cord-322166-ajolu2rh	162	11	+	+	CC
cord-322166-ajolu2rh	162	12	T	T	NNP
cord-322166-ajolu2rh	162	13	cells	cell	NNS
cord-322166-ajolu2rh	162	14	and	and	CC
cord-322166-ajolu2rh	162	15	hyperproduction	hyperproduction	NN
cord-322166-ajolu2rh	162	16	of	of	IN
cord-322166-ajolu2rh	162	17	IFN	IFN	NNP
cord-322166-ajolu2rh	162	18	-	-	HYPH
cord-322166-ajolu2rh	162	19	γ	γ	NNP
cord-322166-ajolu2rh	162	20	has	have	VBZ
cord-322166-ajolu2rh	162	21	occurred	occur	VBN
cord-322166-ajolu2rh	162	22	,	,	,
cord-322166-ajolu2rh	162	23	leading	lead	VBG
cord-322166-ajolu2rh	162	24	to	to	IN
cord-322166-ajolu2rh	162	25	potential	potential	JJ
cord-322166-ajolu2rh	162	26	hyper	hyper	NN
cord-322166-ajolu2rh	162	27	-	-	NN
cord-322166-ajolu2rh	162	28	cytokinemia	cytokinemia	JJ
cord-322166-ajolu2rh	162	29	and	and	CC
cord-322166-ajolu2rh	162	30	hemophagocytosis	hemophagocytosis	NNP
cord-322166-ajolu2rh	163	1	(	(	-LRB-
cord-322166-ajolu2rh	163	2	Hsieh	Hsieh	NNP
cord-322166-ajolu2rh	163	3	S	S	NNP
cord-322166-ajolu2rh	163	4	M	M	NNP
cord-322166-ajolu2rh	163	5	,	,	,
cord-322166-ajolu2rh	163	6	et	et	NNP
cord-322166-ajolu2rh	163	7	al	al	NNP
cord-322166-ajolu2rh	163	8	.	.	NNP
cord-322166-ajolu2rh	163	9	,	,	,
cord-322166-ajolu2rh	163	10	2006	2006	CD
cord-322166-ajolu2rh	163	11	)	)	-RRB-
cord-322166-ajolu2rh	163	12	.	.	.
cord-322166-ajolu2rh	164	1	Finally	finally	RB
cord-322166-ajolu2rh	164	2	,	,	,
cord-322166-ajolu2rh	164	3	production	production	NN
cord-322166-ajolu2rh	164	4	of	of	IN
cord-322166-ajolu2rh	164	5	pulmonary	pulmonary	JJ
cord-322166-ajolu2rh	164	6	surfactant	surfactant	NN
cord-322166-ajolu2rh	164	7	protein	protein	NN
cord-322166-ajolu2rh	164	8	D	D	NNP
cord-322166-ajolu2rh	164	9	was	be	VBD
cord-322166-ajolu2rh	164	10	found	find	VBN
cord-322166-ajolu2rh	164	11	to	to	TO
cord-322166-ajolu2rh	164	12	be	be	VB
cord-322166-ajolu2rh	164	13	down	down	RB
cord-322166-ajolu2rh	164	14	-	-	HYPH
cord-322166-ajolu2rh	164	15	regulated	regulate	VBN
cord-322166-ajolu2rh	164	16	in	in	IN
cord-322166-ajolu2rh	164	17	H5N1	H5N1	NNP
cord-322166-ajolu2rh	164	18	infections	infection	NNS
cord-322166-ajolu2rh	165	1	(	(	-LRB-
cord-322166-ajolu2rh	165	2	Kongchanagul	Kongchanagul	NNP
cord-322166-ajolu2rh	165	3	A	A	NNP
cord-322166-ajolu2rh	165	4	,	,	,
cord-322166-ajolu2rh	165	5	et	et	NNP
cord-322166-ajolu2rh	165	6	al	al	NNP
cord-322166-ajolu2rh	165	7	.	.	NNP
cord-322166-ajolu2rh	165	8	,	,	,
cord-322166-ajolu2rh	165	9	2011	2011	CD
cord-322166-ajolu2rh	165	10	)	)	-RRB-
cord-322166-ajolu2rh	165	11	.	.	.
cord-322166-ajolu2rh	166	1	In	in	IN
cord-322166-ajolu2rh	166	2	humans	human	NNS
cord-322166-ajolu2rh	166	3	,	,	,
cord-322166-ajolu2rh	166	4	the	the	DT
cord-322166-ajolu2rh	166	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	166	6	virus	virus	NN
cord-322166-ajolu2rh	166	7	triggers	trigger	VBZ
cord-322166-ajolu2rh	166	8	a	a	DT
cord-322166-ajolu2rh	166	9	massive	massive	JJ
cord-322166-ajolu2rh	166	10	pro	pro	JJ
cord-322166-ajolu2rh	166	11	-	-	JJ
cord-322166-ajolu2rh	166	12	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	166	13	cytokine	cytokine	NN
cord-322166-ajolu2rh	166	14	and	and	CC
cord-322166-ajolu2rh	166	15	chemokine	chemokine	NN
cord-322166-ajolu2rh	166	16	response	response	NN
cord-322166-ajolu2rh	166	17	that	that	WDT
cord-322166-ajolu2rh	166	18	contributes	contribute	VBZ
cord-322166-ajolu2rh	166	19	to	to	IN
cord-322166-ajolu2rh	166	20	systemic	systemic	JJ
cord-322166-ajolu2rh	166	21	tissue	tissue	NN
cord-322166-ajolu2rh	166	22	damage	damage	NN
cord-322166-ajolu2rh	166	23	and	and	CC
cord-322166-ajolu2rh	166	24	morbidity	morbidity	NN
cord-322166-ajolu2rh	166	25	(	(	-LRB-
cord-322166-ajolu2rh	166	26	de	de	FW
cord-322166-ajolu2rh	166	27	Jong	Jong	NNP
cord-322166-ajolu2rh	166	28	M	M	NNP
cord-322166-ajolu2rh	166	29	D	D	NNP
cord-322166-ajolu2rh	166	30	,	,	,
cord-322166-ajolu2rh	166	31	et	et	NNP
cord-322166-ajolu2rh	166	32	al	al	NNP
cord-322166-ajolu2rh	166	33	.	.	NNP
cord-322166-ajolu2rh	166	34	,	,	,
cord-322166-ajolu2rh	166	35	2006	2006	CD
cord-322166-ajolu2rh	166	36	;	;	:
cord-322166-ajolu2rh	166	37	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	166	38	M	M	NNP
cord-322166-ajolu2rh	166	39	J	J	NNP
cord-322166-ajolu2rh	166	40	,	,	,
cord-322166-ajolu2rh	166	41	2010	2010	CD
cord-322166-ajolu2rh	166	42	;	;	:
cord-322166-ajolu2rh	166	43	Suksatu	Suksatu	NNP
cord-322166-ajolu2rh	166	44	A	A	NNP
cord-322166-ajolu2rh	166	45	,	,	,
cord-322166-ajolu2rh	166	46	et	et	NNP
cord-322166-ajolu2rh	166	47	al	al	NNP
cord-322166-ajolu2rh	166	48	.	.	NNP
cord-322166-ajolu2rh	166	49	,	,	,
cord-322166-ajolu2rh	166	50	2009	2009	CD
cord-322166-ajolu2rh	166	51	;	;	:
cord-322166-ajolu2rh	166	52	Szretter	Szretter	NNP
cord-322166-ajolu2rh	166	53	K	K	NNP
cord-322166-ajolu2rh	166	54	J	J	NNP
cord-322166-ajolu2rh	166	55	,	,	,
cord-322166-ajolu2rh	166	56	et	et	NNP
cord-322166-ajolu2rh	166	57	al	al	NNP
cord-322166-ajolu2rh	166	58	.	.	NNP
cord-322166-ajolu2rh	166	59	,	,	,
cord-322166-ajolu2rh	166	60	2007	2007	CD
cord-322166-ajolu2rh	166	61	)	)	-RRB-
cord-322166-ajolu2rh	166	62	.	.	.
cord-322166-ajolu2rh	167	1	Data	datum	NNS
cord-322166-ajolu2rh	167	2	show	show	VBP
cord-322166-ajolu2rh	167	3	that	that	IN
cord-322166-ajolu2rh	167	4	those	those	DT
cord-322166-ajolu2rh	167	5	who	who	WP
cord-322166-ajolu2rh	167	6	died	die	VBD
cord-322166-ajolu2rh	167	7	from	from	IN
cord-322166-ajolu2rh	167	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	167	9	infection	infection	NN
cord-322166-ajolu2rh	167	10	had	have	VBD
cord-322166-ajolu2rh	167	11	significantly	significantly	RB
cord-322166-ajolu2rh	167	12	higher	high	JJR
cord-322166-ajolu2rh	167	13	levels	level	NNS
cord-322166-ajolu2rh	167	14	of	of	IN
cord-322166-ajolu2rh	167	15	cytokine	cytokine	NN
cord-322166-ajolu2rh	167	16	and	and	CC
cord-322166-ajolu2rh	167	17	chemokine	chemokine	JJ
cord-322166-ajolu2rh	167	18	expression	expression	NN
cord-322166-ajolu2rh	167	19	than	than	IN
cord-322166-ajolu2rh	167	20	survivors	survivor	NNS
cord-322166-ajolu2rh	167	21	.	.	.
cord-322166-ajolu2rh	168	1	IFN	IFN	NNP
cord-322166-ajolu2rh	168	2	-	-	HYPH
cord-322166-ajolu2rh	168	3	αIFN	αIFN	NNP
cord-322166-ajolu2rh	168	4	-	-	HYPH
cord-322166-ajolu2rh	168	5	β	β	NN
cord-322166-ajolu2rh	168	6	,	,	,
cord-322166-ajolu2rh	168	7	IFN	IFN	NNP
cord-322166-ajolu2rh	168	8	-	-	HYPH
cord-322166-ajolu2rh	168	9	λ1	λ1	NNP
cord-322166-ajolu2rh	168	10	,	,	,
cord-322166-ajolu2rh	168	11	TNF	TNF	NNP
cord-322166-ajolu2rh	168	12	-	-	HYPH
cord-322166-ajolu2rh	168	13	α	α	NNP
cord-322166-ajolu2rh	168	14	,	,	,
cord-322166-ajolu2rh	168	15	and	and	CC
cord-322166-ajolu2rh	168	16	RANTES	RANTES	NNPS
cord-322166-ajolu2rh	168	17	were	be	VBD
cord-322166-ajolu2rh	168	18	the	the	DT
cord-322166-ajolu2rh	168	19	primary	primary	JJ
cord-322166-ajolu2rh	168	20	cytokines	cytokine	NNS
cord-322166-ajolu2rh	168	21	induced	induce	VBN
cord-322166-ajolu2rh	168	22	by	by	IN
cord-322166-ajolu2rh	168	23	the	the	DT
cord-322166-ajolu2rh	168	24	H5N1	H5N1	NNP
cord-322166-ajolu2rh	168	25	virus	virus	NN
cord-322166-ajolu2rh	168	26	in	in	IN
cord-322166-ajolu2rh	168	27	macrophages	macrophage	NNS
cord-322166-ajolu2rh	168	28	,	,	,
cord-322166-ajolu2rh	168	29	accompanied	accompany	VBN
cord-322166-ajolu2rh	168	30	by	by	IN
cord-322166-ajolu2rh	168	31	up	up	NN
cord-322166-ajolu2rh	168	32	-	-	HYPH
cord-322166-ajolu2rh	168	33	regulation	regulation	NN
cord-322166-ajolu2rh	168	34	of	of	IN
cord-322166-ajolu2rh	168	35	IRF3	IRF3	NNP
cord-322166-ajolu2rh	168	36	,	,	,
cord-322166-ajolu2rh	168	37	the	the	DT
cord-322166-ajolu2rh	168	38	key	key	JJ
cord-322166-ajolu2rh	168	39	transcription	transcription	NN
cord-322166-ajolu2rh	168	40	factor	factor	NN
cord-322166-ajolu2rh	168	41	for	for	IN
cord-322166-ajolu2rh	168	42	IFN	IFN	NNP
cord-322166-ajolu2rh	168	43	gene	gene	NN
cord-322166-ajolu2rh	168	44	regulation	regulation	NN
cord-322166-ajolu2rh	168	45	(	(	-LRB-
cord-322166-ajolu2rh	168	46	Lee	Lee	NNP
cord-322166-ajolu2rh	168	47	D	D	NNP
cord-322166-ajolu2rh	168	48	C	C	NNP
cord-322166-ajolu2rh	168	49	,	,	,
cord-322166-ajolu2rh	168	50	et	et	NNP
cord-322166-ajolu2rh	168	51	al	al	NNP
cord-322166-ajolu2rh	168	52	.	.	NNP
cord-322166-ajolu2rh	168	53	,	,	,
cord-322166-ajolu2rh	168	54	2005	2005	CD
cord-322166-ajolu2rh	168	55	;	;	:
cord-322166-ajolu2rh	168	56	Lee	Lee	NNP
cord-322166-ajolu2rh	168	57	D	D	NNP
cord-322166-ajolu2rh	168	58	C	C	NNP
cord-322166-ajolu2rh	168	59	,	,	,
cord-322166-ajolu2rh	168	60	et	et	NNP
cord-322166-ajolu2rh	168	61	al	al	NNP
cord-322166-ajolu2rh	168	62	.	.	NNP
cord-322166-ajolu2rh	168	63	,	,	,
cord-322166-ajolu2rh	168	64	2012	2012	CD
cord-322166-ajolu2rh	168	65	)	)	-RRB-
cord-322166-ajolu2rh	168	66	.	.	.
cord-322166-ajolu2rh	169	1	Further	further	RB
cord-322166-ajolu2rh	169	2	,	,	,
cord-322166-ajolu2rh	169	3	up	up	IN
cord-322166-ajolu2rh	169	4	-	-	HYPH
cord-322166-ajolu2rh	169	5	regulation	regulation	NN
cord-322166-ajolu2rh	169	6	of	of	IN
cord-322166-ajolu2rh	169	7	cyclooxygenase	cyclooxygenase	NN
cord-322166-ajolu2rh	169	8	2	2	CD
cord-322166-ajolu2rh	169	9	(	(	-LRB-
cord-322166-ajolu2rh	169	10	COX-2	COX-2	NNP
cord-322166-ajolu2rh	169	11	)	)	-RRB-
cord-322166-ajolu2rh	169	12	,	,	,
cord-322166-ajolu2rh	169	13	followed	follow	VBN
cord-322166-ajolu2rh	169	14	by	by	IN
cord-322166-ajolu2rh	169	15	IL-32	IL-32	NNP
cord-322166-ajolu2rh	169	16	,	,	,
cord-322166-ajolu2rh	170	1	inducible	inducible	JJ
cord-322166-ajolu2rh	170	2	nitric	nitric	NN
cord-322166-ajolu2rh	170	3	oxide	oxide	NN
cord-322166-ajolu2rh	170	4	synthase	synthase	NN
cord-322166-ajolu2rh	170	5	and	and	CC
cord-322166-ajolu2rh	170	6	prostaglandin	prostaglandin	NN
cord-322166-ajolu2rh	170	7	E2	E2	NNP
cord-322166-ajolu2rh	170	8	production	production	NN
cord-322166-ajolu2rh	170	9	and	and	CC
cord-322166-ajolu2rh	170	10	accumulation	accumulation	NN
cord-322166-ajolu2rh	170	11	were	be	VBD
cord-322166-ajolu2rh	170	12	have	have	VBP
cord-322166-ajolu2rh	170	13	been	be	VBN
cord-322166-ajolu2rh	170	14	observed	observe	VBN
cord-322166-ajolu2rh	170	15	in	in	IN
cord-322166-ajolu2rh	170	16	cell	cell	NN
cord-322166-ajolu2rh	170	17	cultures	culture	NNS
cord-322166-ajolu2rh	170	18	and	and	CC
cord-322166-ajolu2rh	170	19	in	in	IN
cord-322166-ajolu2rh	170	20	patients	patient	NNS
cord-322166-ajolu2rh	170	21	with	with	IN
cord-322166-ajolu2rh	170	22	H5N1	H5N1	NNP
cord-322166-ajolu2rh	170	23	infections	infection	NNS
cord-322166-ajolu2rh	170	24	(	(	-LRB-
cord-322166-ajolu2rh	170	25	Li	Li	NNP
cord-322166-ajolu2rh	170	26	W	W	NNP
cord-322166-ajolu2rh	170	27	,	,	,
cord-322166-ajolu2rh	170	28	et	et	NNP
cord-322166-ajolu2rh	170	29	al	al	NNP
cord-322166-ajolu2rh	170	30	.	.	NNP
cord-322166-ajolu2rh	170	31	,	,	,
cord-322166-ajolu2rh	170	32	2010	2010	CD
cord-322166-ajolu2rh	170	33	;	;	.
cord-322166-ajolu2rh	171	1	Li	Li	NNP
cord-322166-ajolu2rh	171	2	W	W	NNP
cord-322166-ajolu2rh	171	3	,	,	,
cord-322166-ajolu2rh	171	4	et	et	NNP
cord-322166-ajolu2rh	171	5	al	al	NNP
cord-322166-ajolu2rh	171	6	.	.	NNP
cord-322166-ajolu2rh	171	7	,	,	,
cord-322166-ajolu2rh	171	8	2009	2009	CD
cord-322166-ajolu2rh	171	9	;	;	:
cord-322166-ajolu2rh	171	10	Li	Li	NNP
cord-322166-ajolu2rh	171	11	W	W	NNP
cord-322166-ajolu2rh	171	12	,	,	,
cord-322166-ajolu2rh	171	13	et	et	NNP
cord-322166-ajolu2rh	171	14	al	al	NNP
cord-322166-ajolu2rh	171	15	.	.	NNP
cord-322166-ajolu2rh	171	16	,	,	,
cord-322166-ajolu2rh	171	17	2008	2008	CD
cord-322166-ajolu2rh	171	18	)	)	-RRB-
cord-322166-ajolu2rh	171	19	.	.	.
cord-322166-ajolu2rh	172	1	The	the	DT
cord-322166-ajolu2rh	172	2	stimulation	stimulation	NN
cord-322166-ajolu2rh	172	3	of	of	IN
cord-322166-ajolu2rh	172	4	COX-2	COX-2	NNP
cord-322166-ajolu2rh	172	5	,	,	,
cord-322166-ajolu2rh	172	6	an	an	DT
cord-322166-ajolu2rh	172	7	inducer	inducer	NN
cord-322166-ajolu2rh	172	8	of	of	IN
cord-322166-ajolu2rh	172	9	IL-27	IL-27	NNP
cord-322166-ajolu2rh	172	10	and	and	CC
cord-322166-ajolu2rh	172	11	IFN	IFN	NNP
cord-322166-ajolu2rh	172	12	-	-	HYPH
cord-322166-ajolu2rh	172	13	λ1	λ1	NNP
cord-322166-ajolu2rh	172	14	,	,	,
cord-322166-ajolu2rh	172	15	acts	act	VBZ
cord-322166-ajolu2rh	172	16	as	as	IN
cord-322166-ajolu2rh	172	17	an	an	DT
cord-322166-ajolu2rh	172	18	important	important	JJ
cord-322166-ajolu2rh	172	19	mediator	mediator	NN
cord-322166-ajolu2rh	172	20	of	of	IN
cord-322166-ajolu2rh	172	21	the	the	DT
cord-322166-ajolu2rh	172	22	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	172	23	response	response	NN
cord-322166-ajolu2rh	172	24	during	during	IN
cord-322166-ajolu2rh	172	25	influenza	influenza	NN
cord-322166-ajolu2rh	172	26	virus	virus	NN
cord-322166-ajolu2rh	172	27	infection	infection	NN
cord-322166-ajolu2rh	172	28	(	(	-LRB-
cord-322166-ajolu2rh	172	29	Fang	Fang	NNP
cord-322166-ajolu2rh	172	30	J	J	NNP
cord-322166-ajolu2rh	172	31	,	,	,
cord-322166-ajolu2rh	172	32	et	et	NNP
cord-322166-ajolu2rh	172	33	al	al	NNP
cord-322166-ajolu2rh	172	34	.	.	NNP
cord-322166-ajolu2rh	172	35	,	,	,
cord-322166-ajolu2rh	172	36	2011	2011	CD
cord-322166-ajolu2rh	172	37	;	;	:
cord-322166-ajolu2rh	172	38	Liu	Liu	NNP
cord-322166-ajolu2rh	172	39	L	L	NNP
cord-322166-ajolu2rh	172	40	,	,	,
cord-322166-ajolu2rh	172	41	et	et	NNP
cord-322166-ajolu2rh	172	42	al	al	NNP
cord-322166-ajolu2rh	172	43	.	.	NNP
cord-322166-ajolu2rh	172	44	,	,	,
cord-322166-ajolu2rh	172	45	2012	2012	CD
cord-322166-ajolu2rh	172	46	)	)	-RRB-
cord-322166-ajolu2rh	172	47	.	.	.
cord-322166-ajolu2rh	173	1	Although	although	IN
cord-322166-ajolu2rh	173	2	results	result	NNS
cord-322166-ajolu2rh	173	3	of	of	IN
cord-322166-ajolu2rh	173	4	previous	previous	JJ
cord-322166-ajolu2rh	173	5	studies	study	NNS
cord-322166-ajolu2rh	173	6	using	use	VBG
cord-322166-ajolu2rh	173	7	different	different	JJ
cord-322166-ajolu2rh	173	8	model	model	NN
cord-322166-ajolu2rh	173	9	systems	system	NNS
cord-322166-ajolu2rh	173	10	(	(	-LRB-
cord-322166-ajolu2rh	173	11	both	both	DT
cord-322166-ajolu2rh	173	12	animals	animal	NNS
cord-322166-ajolu2rh	173	13	and	and	CC
cord-322166-ajolu2rh	173	14	cultured	cultured	JJ
cord-322166-ajolu2rh	173	15	cells	cell	NNS
cord-322166-ajolu2rh	173	16	)	)	-RRB-
cord-322166-ajolu2rh	173	17	did	do	VBD
cord-322166-ajolu2rh	173	18	not	not	RB
cord-322166-ajolu2rh	173	19	completely	completely	RB
cord-322166-ajolu2rh	173	20	agree	agree	VB
cord-322166-ajolu2rh	173	21	,	,	,
cord-322166-ajolu2rh	173	22	they	-PRON-	PRP
cord-322166-ajolu2rh	173	23	did	do	VBD
cord-322166-ajolu2rh	173	24	lead	lead	VB
cord-322166-ajolu2rh	173	25	to	to	IN
cord-322166-ajolu2rh	173	26	a	a	DT
cord-322166-ajolu2rh	173	27	consensus	consensus	NN
cord-322166-ajolu2rh	173	28	that	that	WDT
cord-322166-ajolu2rh	173	29	H5N1	H5N1	NNP
cord-322166-ajolu2rh	173	30	virus	virus	NN
cord-322166-ajolu2rh	173	31	induces	induce	VBZ
cord-322166-ajolu2rh	173	32	a	a	DT
cord-322166-ajolu2rh	173	33	'	'	``
cord-322166-ajolu2rh	173	34	cytokine	cytokine	NN
cord-322166-ajolu2rh	173	35	storm	storm	NN
cord-322166-ajolu2rh	173	36	'	'	''
cord-322166-ajolu2rh	173	37	(	(	-LRB-
cord-322166-ajolu2rh	173	38	Yu	Yu	NNP
cord-322166-ajolu2rh	173	39	W	W	NNP
cord-322166-ajolu2rh	173	40	C	C	NNP
cord-322166-ajolu2rh	173	41	,	,	,
cord-322166-ajolu2rh	173	42	et	et	NNP
cord-322166-ajolu2rh	173	43	al	al	NNP
cord-322166-ajolu2rh	173	44	.	.	NNP
cord-322166-ajolu2rh	173	45	,	,	,
cord-322166-ajolu2rh	173	46	2011	2011	CD
cord-322166-ajolu2rh	173	47	)	)	-RRB-
cord-322166-ajolu2rh	173	48	.	.	.
cord-322166-ajolu2rh	174	1	Thus	thus	RB
cord-322166-ajolu2rh	174	2	,	,	,
cord-322166-ajolu2rh	174	3	patients	patient	NNS
cord-322166-ajolu2rh	174	4	with	with	IN
cord-322166-ajolu2rh	174	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	174	6	disease	disease	NN
cord-322166-ajolu2rh	174	7	typically	typically	RB
cord-322166-ajolu2rh	174	8	present	present	VBP
cord-322166-ajolu2rh	174	9	with	with	IN
cord-322166-ajolu2rh	174	10	a	a	DT
cord-322166-ajolu2rh	174	11	hyper	hyper	RB
cord-322166-ajolu2rh	174	12	-	-	JJ
cord-322166-ajolu2rh	174	13	induced	induced	JJ
cord-322166-ajolu2rh	174	14	systemic	systemic	JJ
cord-322166-ajolu2rh	174	15	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	174	16	response	response	NN
cord-322166-ajolu2rh	174	17	syndrome	syndrome	NN
cord-322166-ajolu2rh	174	18	and	and	CC
cord-322166-ajolu2rh	174	19	a	a	DT
cord-322166-ajolu2rh	174	20	higher	high	JJR
cord-322166-ajolu2rh	174	21	and	and	CC
cord-322166-ajolu2rh	174	22	a	a	DT
cord-322166-ajolu2rh	174	23	more	more	RBR
cord-322166-ajolu2rh	174	24	prolonged	prolonged	JJ
cord-322166-ajolu2rh	174	25	viral	viral	JJ
cord-322166-ajolu2rh	174	26	load	load	NN
cord-322166-ajolu2rh	174	27	in	in	IN
cord-322166-ajolu2rh	174	28	respiratory	respiratory	JJ
cord-322166-ajolu2rh	174	29	specimens	specimen	NNS
cord-322166-ajolu2rh	174	30	than	than	IN
cord-322166-ajolu2rh	174	31	other	other	JJ
cord-322166-ajolu2rh	174	32	seasonal	seasonal	JJ
cord-322166-ajolu2rh	174	33	influenza	influenza	NN
cord-322166-ajolu2rh	174	34	virus	virus	NN
cord-322166-ajolu2rh	174	35	like	like	IN
cord-322166-ajolu2rh	174	36	human	human	JJ
cord-322166-ajolu2rh	174	37	H1N1	H1N1	NNP
cord-322166-ajolu2rh	174	38	viruses	virus	NNS
cord-322166-ajolu2rh	175	1	(	(	-LRB-
cord-322166-ajolu2rh	175	2	Chan	Chan	NNP
cord-322166-ajolu2rh	175	3	M	M	NNP
cord-322166-ajolu2rh	175	4	C	C	NNP
cord-322166-ajolu2rh	175	5	,	,	,
cord-322166-ajolu2rh	175	6	et	et	NNP
cord-322166-ajolu2rh	175	7	al	al	NNP
cord-322166-ajolu2rh	175	8	.	.	NNP
cord-322166-ajolu2rh	175	9	,	,	,
cord-322166-ajolu2rh	175	10	2005	2005	CD
cord-322166-ajolu2rh	175	11	;	;	:
cord-322166-ajolu2rh	175	12	Kuiken	Kuiken	NNP
cord-322166-ajolu2rh	175	13	T	T	NNP
cord-322166-ajolu2rh	175	14	,	,	,
cord-322166-ajolu2rh	175	15	et	et	NNP
cord-322166-ajolu2rh	175	16	al	al	NNP
cord-322166-ajolu2rh	175	17	.	.	NNP
cord-322166-ajolu2rh	175	18	,	,	,
cord-322166-ajolu2rh	175	19	2010	2010	CD
cord-322166-ajolu2rh	175	20	;	;	:
cord-322166-ajolu2rh	175	21	Lee	Lee	NNP
cord-322166-ajolu2rh	175	22	D	D	NNP
cord-322166-ajolu2rh	175	23	C	C	NNP
cord-322166-ajolu2rh	175	24	,	,	,
cord-322166-ajolu2rh	175	25	et	et	NNP
cord-322166-ajolu2rh	175	26	al	al	NNP
cord-322166-ajolu2rh	175	27	.	.	NNP
cord-322166-ajolu2rh	175	28	,	,	,
cord-322166-ajolu2rh	175	29	2012	2012	CD
cord-322166-ajolu2rh	175	30	;	;	:
cord-322166-ajolu2rh	175	31	Peiris	Peiris	NNP
cord-322166-ajolu2rh	175	32	J	J	NNP
cord-322166-ajolu2rh	175	33	S	S	NNP
cord-322166-ajolu2rh	175	34	,	,	,
cord-322166-ajolu2rh	175	35	et	et	NNP
cord-322166-ajolu2rh	175	36	al	al	NNP
cord-322166-ajolu2rh	175	37	.	.	NNP
cord-322166-ajolu2rh	175	38	,	,	,
cord-322166-ajolu2rh	175	39	2010	2010	CD
cord-322166-ajolu2rh	175	40	;	;	:
cord-322166-ajolu2rh	175	41	Sandbulte	Sandbulte	NNP
cord-322166-ajolu2rh	175	42	M	M	NNP
cord-322166-ajolu2rh	175	43	R	R	NNP
cord-322166-ajolu2rh	175	44	,	,	,
cord-322166-ajolu2rh	175	45	et	et	NNP
cord-322166-ajolu2rh	175	46	al	al	NNP
cord-322166-ajolu2rh	175	47	.	.	NNP
cord-322166-ajolu2rh	175	48	,	,	,
cord-322166-ajolu2rh	175	49	2008	2008	CD
cord-322166-ajolu2rh	175	50	)	)	-RRB-
cord-322166-ajolu2rh	175	51	.	.	.
cord-322166-ajolu2rh	176	1	The	the	DT
cord-322166-ajolu2rh	176	2	outcomes	outcome	NNS
cord-322166-ajolu2rh	176	3	of	of	IN
cord-322166-ajolu2rh	176	4	this	this	DT
cord-322166-ajolu2rh	176	5	imbalance	imbalance	NN
cord-322166-ajolu2rh	176	6	are	be	VBP
cord-322166-ajolu2rh	176	7	always	always	RB
cord-322166-ajolu2rh	176	8	associated	associate	VBN
cord-322166-ajolu2rh	176	9	with	with	IN
cord-322166-ajolu2rh	176	10	fulminant	fulminant	JJ
cord-322166-ajolu2rh	176	11	viral	viral	JJ
cord-322166-ajolu2rh	176	12	pneumonia	pneumonia	NN
cord-322166-ajolu2rh	176	13	followed	follow	VBN
cord-322166-ajolu2rh	176	14	by	by	IN
cord-322166-ajolu2rh	176	15	acute	acute	JJ
cord-322166-ajolu2rh	176	16	respiratory	respiratory	JJ
cord-322166-ajolu2rh	176	17	distress	distress	NN
cord-322166-ajolu2rh	176	18	syndrome	syndrome	NN
cord-322166-ajolu2rh	176	19	,	,	,
cord-322166-ajolu2rh	176	20	multi	multi	JJ
cord-322166-ajolu2rh	176	21	-	-	JJ
cord-322166-ajolu2rh	176	22	organ	organ	JJ
cord-322166-ajolu2rh	176	23	failure	failure	NN
cord-322166-ajolu2rh	176	24	,	,	,
cord-322166-ajolu2rh	177	1	and/or	and/or	CC
cord-322166-ajolu2rh	178	1	often	often	RB
cord-322166-ajolu2rh	178	2	death	death	NN
cord-322166-ajolu2rh	178	3	(	(	-LRB-
cord-322166-ajolu2rh	178	4	de	de	FW
cord-322166-ajolu2rh	178	5	Jong	Jong	NNP
cord-322166-ajolu2rh	178	6	M	M	NNP
cord-322166-ajolu2rh	178	7	D	D	NNP
cord-322166-ajolu2rh	178	8	,	,	,
cord-322166-ajolu2rh	178	9	et	et	NNP
cord-322166-ajolu2rh	178	10	al	al	NNP
cord-322166-ajolu2rh	178	11	.	.	NNP
cord-322166-ajolu2rh	178	12	,	,	,
cord-322166-ajolu2rh	178	13	2006	2006	CD
cord-322166-ajolu2rh	178	14	;	;	:
cord-322166-ajolu2rh	178	15	Szretter	Szretter	NNP
cord-322166-ajolu2rh	178	16	K	K	NNP
cord-322166-ajolu2rh	178	17	J	J	NNP
cord-322166-ajolu2rh	178	18	,	,	,
cord-322166-ajolu2rh	178	19	et	et	NNP
cord-322166-ajolu2rh	178	20	al	al	NNP
cord-322166-ajolu2rh	178	21	.	.	NNP
cord-322166-ajolu2rh	178	22	,	,	,
cord-322166-ajolu2rh	178	23	2007	2007	CD
cord-322166-ajolu2rh	178	24	)	)	-RRB-
cord-322166-ajolu2rh	178	25	.	.	.
cord-322166-ajolu2rh	179	1	Most	Most	JJS
cord-322166-ajolu2rh	179	2	pro	pro	JJ
cord-322166-ajolu2rh	179	3	-	-	JJ
cord-322166-ajolu2rh	179	4	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	179	5	cytokines	cytokine	NNS
cord-322166-ajolu2rh	179	6	and	and	CC
cord-322166-ajolu2rh	179	7	chemokines	chemokine	NNS
cord-322166-ajolu2rh	179	8	reach	reach	VBP
cord-322166-ajolu2rh	179	9	higher	high	JJR
cord-322166-ajolu2rh	179	10	levels	level	NNS
cord-322166-ajolu2rh	179	11	in	in	IN
cord-322166-ajolu2rh	179	12	the	the	DT
cord-322166-ajolu2rh	179	13	serum	serum	NN
cord-322166-ajolu2rh	179	14	of	of	IN
cord-322166-ajolu2rh	179	15	H5N1-infected	h5n1-infected	JJ
cord-322166-ajolu2rh	179	16	individuals	individual	NNS
cord-322166-ajolu2rh	179	17	than	than	IN
cord-322166-ajolu2rh	179	18	comparable	comparable	JJ
cord-322166-ajolu2rh	179	19	samples	sample	NNS
cord-322166-ajolu2rh	179	20	from	from	IN
cord-322166-ajolu2rh	179	21	seasonal	seasonal	JJ
cord-322166-ajolu2rh	179	22	human	human	JJ
cord-322166-ajolu2rh	179	23	influenza	influenza	NN
cord-322166-ajolu2rh	179	24	virus	virus	NN
cord-322166-ajolu2rh	179	25	-	-	HYPH
cord-322166-ajolu2rh	179	26	infected	infect	VBN
cord-322166-ajolu2rh	179	27	individuals	individual	NNS
cord-322166-ajolu2rh	179	28	(	(	-LRB-
cord-322166-ajolu2rh	179	29	Lee	Lee	NNP
cord-322166-ajolu2rh	179	30	S	S	NNP
cord-322166-ajolu2rh	179	31	M	M	NNP
cord-322166-ajolu2rh	179	32	,	,	,
cord-322166-ajolu2rh	179	33	et	et	NNP
cord-322166-ajolu2rh	179	34	al	al	NNP
cord-322166-ajolu2rh	179	35	.	.	NNP
cord-322166-ajolu2rh	179	36	,	,	,
cord-322166-ajolu2rh	179	37	2009	2009	CD
cord-322166-ajolu2rh	179	38	)	)	-RRB-
cord-322166-ajolu2rh	179	39	.	.	.
cord-322166-ajolu2rh	180	1	In	in	IN
cord-322166-ajolu2rh	180	2	H5N1-infected	h5n1-infected	JJ
cord-322166-ajolu2rh	180	3	primary	primary	JJ
cord-322166-ajolu2rh	180	4	human	human	JJ
cord-322166-ajolu2rh	180	5	macrophages	macrophage	NNS
cord-322166-ajolu2rh	180	6	,	,	,
cord-322166-ajolu2rh	180	7	many	many	JJ
cord-322166-ajolu2rh	180	8	genes	gene	NNS
cord-322166-ajolu2rh	180	9	showed	show	VBD
cord-322166-ajolu2rh	180	10	at	at	IN
cord-322166-ajolu2rh	180	11	least	least	JJS
cord-322166-ajolu2rh	180	12	a	a	DT
cord-322166-ajolu2rh	180	13	1.5-fold	1.5-fold	CD
cord-322166-ajolu2rh	180	14	greater	great	JJR
cord-322166-ajolu2rh	180	15	response	response	NN
cord-322166-ajolu2rh	180	16	than	than	IN
cord-322166-ajolu2rh	180	17	the	the	DT
cord-322166-ajolu2rh	180	18	response	response	NN
cord-322166-ajolu2rh	180	19	observed	observe	VBN
cord-322166-ajolu2rh	180	20	in	in	IN
cord-322166-ajolu2rh	180	21	seasonal	seasonal	JJ
cord-322166-ajolu2rh	180	22	H1N1-infected	h1n1-infecte	VBN
cord-322166-ajolu2rh	180	23	cells	cell	NNS
cord-322166-ajolu2rh	180	24	at	at	IN
cord-322166-ajolu2rh	180	25	6	6	CD
cord-322166-ajolu2rh	180	26	hours	hour	NNS
cord-322166-ajolu2rh	180	27	post	post	NN
cord-322166-ajolu2rh	180	28	-	-	NN
cord-322166-ajolu2rh	180	29	infection	infection	NN
cord-322166-ajolu2rh	180	30	.	.	.
cord-322166-ajolu2rh	181	1	Of	of	IN
cord-322166-ajolu2rh	181	2	those	those	DT
cord-322166-ajolu2rh	181	3	genes	gene	NNS
cord-322166-ajolu2rh	181	4	,	,	,
cord-322166-ajolu2rh	181	5	TNF	TNF	NNP
cord-322166-ajolu2rh	181	6	,	,	,
cord-322166-ajolu2rh	181	7	CCL4L1	CCL4L1	NNP
cord-322166-ajolu2rh	181	8	,	,	,
cord-322166-ajolu2rh	181	9	IFIT2	IFIT2	NNP
cord-322166-ajolu2rh	181	10	,	,	,
cord-322166-ajolu2rh	181	11	and	and	CC
cord-322166-ajolu2rh	181	12	PMAIP1	PMAIP1	NNS
cord-322166-ajolu2rh	181	13	were	be	VBD
cord-322166-ajolu2rh	181	14	also	also	RB
cord-322166-ajolu2rh	181	15	up	up	RB
cord-322166-ajolu2rh	181	16	-	-	HYPH
cord-322166-ajolu2rh	181	17	regulated	regulate	VBN
cord-322166-ajolu2rh	181	18	to	to	IN
cord-322166-ajolu2rh	181	19	a	a	DT
cord-322166-ajolu2rh	181	20	greater	great	JJR
cord-322166-ajolu2rh	181	21	degree	degree	NN
cord-322166-ajolu2rh	181	22	at	at	IN
cord-322166-ajolu2rh	181	23	3	3	CD
cord-322166-ajolu2rh	181	24	hours	hour	NNS
cord-322166-ajolu2rh	181	25	post	post	NN
cord-322166-ajolu2rh	181	26	-	-	NN
cord-322166-ajolu2rh	181	27	infection	infection	JJ
cord-322166-ajolu2rh	182	1	(	(	-LRB-
cord-322166-ajolu2rh	182	2	Lee	Lee	NNP
cord-322166-ajolu2rh	182	3	S	S	NNP
cord-322166-ajolu2rh	182	4	M	M	NNP
cord-322166-ajolu2rh	182	5	,	,	,
cord-322166-ajolu2rh	182	6	et	et	NNP
cord-322166-ajolu2rh	182	7	al	al	NNP
cord-322166-ajolu2rh	182	8	.	.	NNP
cord-322166-ajolu2rh	182	9	,	,	,
cord-322166-ajolu2rh	182	10	2009	2009	CD
cord-322166-ajolu2rh	182	11	)	)	-RRB-
cord-322166-ajolu2rh	182	12	.	.	.
cord-322166-ajolu2rh	183	1	The	the	DT
cord-322166-ajolu2rh	183	2	negative	negative	JJ
cord-322166-ajolu2rh	183	3	effector	effector	NN
cord-322166-ajolu2rh	183	4	of	of	IN
cord-322166-ajolu2rh	183	5	Fas	Fas	NNP
cord-322166-ajolu2rh	183	6	(	(	-LRB-
cord-322166-ajolu2rh	183	7	Nef	Nef	NNP
cord-322166-ajolu2rh	183	8	)	)	-RRB-
cord-322166-ajolu2rh	183	9	and	and	CC
cord-322166-ajolu2rh	183	10	TNF	TNF	NNP
cord-322166-ajolu2rh	183	11	-	-	HYPH
cord-322166-ajolu2rh	183	12	α	α	NN
cord-322166-ajolu2rh	183	13	seem	seem	VBP
cord-322166-ajolu2rh	183	14	to	to	TO
cord-322166-ajolu2rh	183	15	be	be	VB
cord-322166-ajolu2rh	183	16	unique	unique	JJ
cord-322166-ajolu2rh	183	17	to	to	IN
cord-322166-ajolu2rh	183	18	H5N1	H5N1	NNP
cord-322166-ajolu2rh	183	19	infection	infection	NN
cord-322166-ajolu2rh	184	1	(	(	-LRB-
cord-322166-ajolu2rh	184	2	Lee	Lee	NNP
cord-322166-ajolu2rh	184	3	S	S	NNP
cord-322166-ajolu2rh	184	4	M	M	NNP
cord-322166-ajolu2rh	184	5	,	,	,
cord-322166-ajolu2rh	184	6	et	et	NNP
cord-322166-ajolu2rh	184	7	al	al	NNP
cord-322166-ajolu2rh	184	8	.	.	NNP
cord-322166-ajolu2rh	184	9	,	,	,
cord-322166-ajolu2rh	184	10	2009	2009	CD
cord-322166-ajolu2rh	184	11	)	)	-RRB-
cord-322166-ajolu2rh	184	12	.	.	.
cord-322166-ajolu2rh	185	1	Despite	despite	IN
cord-322166-ajolu2rh	185	2	the	the	DT
cord-322166-ajolu2rh	185	3	increased	increase	VBN
cord-322166-ajolu2rh	185	4	expression	expression	NN
cord-322166-ajolu2rh	185	5	of	of	IN
cord-322166-ajolu2rh	185	6	IFN	IFN	NNP
cord-322166-ajolu2rh	185	7	-	-	HYPH
cord-322166-ajolu2rh	185	8	α	α	NNP
cord-322166-ajolu2rh	185	9	and	and	CC
cord-322166-ajolu2rh	185	10	IFN	IFN	NNP
cord-322166-ajolu2rh	185	11	-	-	HYPH
cord-322166-ajolu2rh	185	12	β	β	NNP
cord-322166-ajolu2rh	185	13	,	,	,
cord-322166-ajolu2rh	185	14	an	an	DT
cord-322166-ajolu2rh	185	15	up	up	JJ
cord-322166-ajolu2rh	185	16	-	-	HYPH
cord-322166-ajolu2rh	185	17	regulation	regulation	NN
cord-322166-ajolu2rh	185	18	of	of	IN
cord-322166-ajolu2rh	185	19	IL-29	IL-29	NNP
cord-322166-ajolu2rh	185	20	,	,	,
cord-322166-ajolu2rh	185	21	which	which	WDT
cord-322166-ajolu2rh	185	22	was	be	VBD
cord-322166-ajolu2rh	185	23	not	not	RB
cord-322166-ajolu2rh	185	24	detected	detect	VBN
cord-322166-ajolu2rh	185	25	during	during	IN
cord-322166-ajolu2rh	185	26	H1N1	H1N1	NNP
cord-322166-ajolu2rh	185	27	infections	infection	NNS
cord-322166-ajolu2rh	185	28	,	,	,
cord-322166-ajolu2rh	185	29	has	have	VBZ
cord-322166-ajolu2rh	185	30	also	also	RB
cord-322166-ajolu2rh	185	31	been	be	VBN
cord-322166-ajolu2rh	185	32	observed	observe	VBN
cord-322166-ajolu2rh	185	33	following	follow	VBG
cord-322166-ajolu2rh	185	34	H5N1	H5N1	NNP
cord-322166-ajolu2rh	185	35	infection	infection	NN
cord-322166-ajolu2rh	185	36	,	,	,
cord-322166-ajolu2rh	185	37	leading	lead	VBG
cord-322166-ajolu2rh	185	38	to	to	IN
cord-322166-ajolu2rh	185	39	enhanced	enhanced	JJ
cord-322166-ajolu2rh	185	40	signaling	signaling	NN
cord-322166-ajolu2rh	185	41	through	through	IN
cord-322166-ajolu2rh	185	42	the	the	DT
cord-322166-ajolu2rh	185	43	Jak	Jak	NNP
cord-322166-ajolu2rh	185	44	-	-	HYPH
cord-322166-ajolu2rh	185	45	STAT	STAT	NNP
cord-322166-ajolu2rh	185	46	pathway	pathway	NN
cord-322166-ajolu2rh	185	47	(	(	-LRB-
cord-322166-ajolu2rh	185	48	Lee	Lee	NNP
cord-322166-ajolu2rh	185	49	S	S	NNP
cord-322166-ajolu2rh	185	50	M	M	NNP
cord-322166-ajolu2rh	185	51	,	,	,
cord-322166-ajolu2rh	185	52	et	et	NNP
cord-322166-ajolu2rh	185	53	al	al	NNP
cord-322166-ajolu2rh	185	54	.	.	NNP
cord-322166-ajolu2rh	185	55	,	,	,
cord-322166-ajolu2rh	185	56	2009	2009	CD
cord-322166-ajolu2rh	185	57	)	)	-RRB-
cord-322166-ajolu2rh	185	58	.	.	.
cord-322166-ajolu2rh	186	1	Further	further	RB
cord-322166-ajolu2rh	186	2	,	,	,
cord-322166-ajolu2rh	186	3	avian	avian	JJ
cord-322166-ajolu2rh	186	4	H5N1	H5N1	NNP
cord-322166-ajolu2rh	186	5	infection	infection	NN
cord-322166-ajolu2rh	186	6	triggered	trigger	VBD
cord-322166-ajolu2rh	186	7	a	a	DT
cord-322166-ajolu2rh	186	8	delayed	delay	VBN
cord-322166-ajolu2rh	186	9	onset	onset	NN
cord-322166-ajolu2rh	186	10	of	of	IN
cord-322166-ajolu2rh	186	11	caspaseand	caspaseand	NNP
cord-322166-ajolu2rh	186	12	poly	poly	JJ
cord-322166-ajolu2rh	186	13	(	(	-LRB-
cord-322166-ajolu2rh	186	14	ADP	ADP	NNP
cord-322166-ajolu2rh	186	15	-	-	HYPH
cord-322166-ajolu2rh	186	16	ribose	ribose	NN
cord-322166-ajolu2rh	186	17	)	)	-RRB-
cord-322166-ajolu2rh	186	18	polymerase	polymerase	NN
cord-322166-ajolu2rh	186	19	(	(	-LRB-
cord-322166-ajolu2rh	186	20	PARP)-mediated	parp)-mediated	CD
cord-322166-ajolu2rh	186	21	apoptotic	apoptotic	JJ
cord-322166-ajolu2rh	186	22	pathways	pathway	NNS
cord-322166-ajolu2rh	186	23	,	,	,
cord-322166-ajolu2rh	186	24	resulting	result	VBG
cord-322166-ajolu2rh	186	25	in	in	IN
cord-322166-ajolu2rh	186	26	a	a	DT
cord-322166-ajolu2rh	186	27	decreased	decreased	JJ
cord-322166-ajolu2rh	186	28	percentage	percentage	NN
cord-322166-ajolu2rh	186	29	of	of	IN
cord-322166-ajolu2rh	186	30	cell	cell	NN
cord-322166-ajolu2rh	186	31	death	death	NN
cord-322166-ajolu2rh	186	32	and	and	CC
cord-322166-ajolu2rh	186	33	expression	expression	NN
cord-322166-ajolu2rh	186	34	level	level	NN
cord-322166-ajolu2rh	186	35	of	of	IN
cord-322166-ajolu2rh	186	36	the	the	DT
cord-322166-ajolu2rh	186	37	PARP	PARP	NNP
cord-322166-ajolu2rh	186	38	fragment	fragment	NN
cord-322166-ajolu2rh	186	39	than	than	IN
cord-322166-ajolu2rh	186	40	that	that	DT
cord-322166-ajolu2rh	186	41	observed	observe	VBD
cord-322166-ajolu2rh	186	42	with	with	IN
cord-322166-ajolu2rh	186	43	the	the	DT
cord-322166-ajolu2rh	186	44	H1N1	H1N1	NNP
cord-322166-ajolu2rh	186	45	virus	virus	NN
cord-322166-ajolu2rh	186	46	(	(	-LRB-
cord-322166-ajolu2rh	186	47	Mok	Mok	NNP
cord-322166-ajolu2rh	186	48	C	C	NNP
cord-322166-ajolu2rh	186	49	K	K	NNP
cord-322166-ajolu2rh	186	50	,	,	,
cord-322166-ajolu2rh	186	51	et	et	NNP
cord-322166-ajolu2rh	186	52	al	al	NNP
cord-322166-ajolu2rh	186	53	.	.	NNP
cord-322166-ajolu2rh	186	54	,	,	,
cord-322166-ajolu2rh	186	55	2007	2007	CD
cord-322166-ajolu2rh	186	56	)	)	-RRB-
cord-322166-ajolu2rh	186	57	.	.	.
cord-322166-ajolu2rh	187	1	Similar	similar	JJ
cord-322166-ajolu2rh	187	2	results	result	NNS
cord-322166-ajolu2rh	187	3	have	have	VBP
cord-322166-ajolu2rh	187	4	also	also	RB
cord-322166-ajolu2rh	187	5	been	be	VBN
cord-322166-ajolu2rh	187	6	seen	see	VBN
cord-322166-ajolu2rh	187	7	in	in	IN
cord-322166-ajolu2rh	187	8	previous	previous	JJ
cord-322166-ajolu2rh	187	9	studies	study	NNS
cord-322166-ajolu2rh	187	10	using	use	VBG
cord-322166-ajolu2rh	187	11	other	other	JJ
cord-322166-ajolu2rh	187	12	types	type	NNS
cord-322166-ajolu2rh	187	13	of	of	IN
cord-322166-ajolu2rh	187	14	human	human	JJ
cord-322166-ajolu2rh	187	15	cells	cell	NNS
cord-322166-ajolu2rh	187	16	and	and	CC
cord-322166-ajolu2rh	187	17	animal	animal	NN
cord-322166-ajolu2rh	187	18	models	model	NNS
cord-322166-ajolu2rh	187	19	.	.	.
cord-322166-ajolu2rh	188	1	Much	much	RB
cord-322166-ajolu2rh	188	2	stronger	strong	JJR
cord-322166-ajolu2rh	188	3	natural	natural	JJ
cord-322166-ajolu2rh	188	4	killer	killer	NN
cord-322166-ajolu2rh	188	5	(	(	-LRB-
cord-322166-ajolu2rh	188	6	NK	NK	NNP
cord-322166-ajolu2rh	188	7	)	)	-RRB-
cord-322166-ajolu2rh	188	8	cell	cell	NN
cord-322166-ajolu2rh	188	9	activation	activation	NN
cord-322166-ajolu2rh	188	10	,	,	,
cord-322166-ajolu2rh	188	11	followed	follow	VBN
cord-322166-ajolu2rh	188	12	by	by	IN
cord-322166-ajolu2rh	188	13	up	up	NN
cord-322166-ajolu2rh	188	14	-	-	HYPH
cord-322166-ajolu2rh	188	15	regulation	regulation	NN
cord-322166-ajolu2rh	188	16	of	of	IN
cord-322166-ajolu2rh	188	17	CD69	CD69	NNP
cord-322166-ajolu2rh	188	18	and	and	CC
cord-322166-ajolu2rh	188	19	CD107a	CD107a	NNP
cord-322166-ajolu2rh	188	20	,	,	,
cord-322166-ajolu2rh	188	21	significantly	significantly	RB
cord-322166-ajolu2rh	188	22	enhanced	enhance	VBN
cord-322166-ajolu2rh	188	23	expression	expression	NN
cord-322166-ajolu2rh	188	24	of	of	IN
cord-322166-ajolu2rh	188	25	IFN	IFN	NNP
cord-322166-ajolu2rh	188	26	-	-	HYPH
cord-322166-ajolu2rh	188	27	γ	γ	NNP
cord-322166-ajolu2rh	188	28	production	production	NN
cord-322166-ajolu2rh	188	29	,	,	,
cord-322166-ajolu2rh	188	30	and	and	CC
cord-322166-ajolu2rh	188	31	down	down	JJ
cord-322166-ajolu2rh	188	32	-	-	HYPH
cord-322166-ajolu2rh	188	33	regulation	regulation	NN
cord-322166-ajolu2rh	188	34	of	of	IN
cord-322166-ajolu2rh	188	35	NKp46	NKp46	NNS
cord-322166-ajolu2rh	188	36	have	have	VBP
cord-322166-ajolu2rh	188	37	also	also	RB
cord-322166-ajolu2rh	188	38	been	be	VBN
cord-322166-ajolu2rh	188	39	observed	observe	VBN
cord-322166-ajolu2rh	188	40	in	in	IN
cord-322166-ajolu2rh	188	41	H5N1	H5N1	NNP
cord-322166-ajolu2rh	188	42	infection	infection	NN
cord-322166-ajolu2rh	189	1	(	(	-LRB-
cord-322166-ajolu2rh	189	2	Du	Du	NNP
cord-322166-ajolu2rh	189	3	N	N	NNP
cord-322166-ajolu2rh	189	4	,	,	,
cord-322166-ajolu2rh	189	5	et	et	NNP
cord-322166-ajolu2rh	189	6	al	al	NNP
cord-322166-ajolu2rh	189	7	.	.	NNP
cord-322166-ajolu2rh	189	8	,	,	,
cord-322166-ajolu2rh	189	9	2010	2010	CD
cord-322166-ajolu2rh	189	10	)	)	-RRB-
cord-322166-ajolu2rh	189	11	.	.	.
cord-322166-ajolu2rh	190	1	H5N1	H5N1	NNP
cord-322166-ajolu2rh	190	2	virus	virus	NN
cord-322166-ajolu2rh	190	3	can	can	MD
cord-322166-ajolu2rh	190	4	also	also	RB
cord-322166-ajolu2rh	190	5	hyper	hyper	VB
cord-322166-ajolu2rh	190	6	-	-	JJ
cord-322166-ajolu2rh	190	7	induce	induce	VB
cord-322166-ajolu2rh	190	8	pro	pro	JJ
cord-322166-ajolu2rh	190	9	-	-	JJ
cord-322166-ajolu2rh	190	10	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	190	11	cytokines	cytokine	NNS
cord-322166-ajolu2rh	190	12	including	include	VBG
cord-322166-ajolu2rh	190	13	TNF	TNF	NNP
cord-322166-ajolu2rh	190	14	-	-	HYPH
cord-322166-ajolu2rh	190	15	α	α	NNP
cord-322166-ajolu2rh	190	16	,	,	,
cord-322166-ajolu2rh	190	17	with	with	IN
cord-322166-ajolu2rh	190	18	enhanced	enhance	VBN
cord-322166-ajolu2rh	190	19	TNF	tnf	NN
cord-322166-ajolu2rh	190	20	-	-	HYPH
cord-322166-ajolu2rh	190	21	related	relate	VBN
cord-322166-ajolu2rh	190	22	apoptosis	apoptosis	NN
cord-322166-ajolu2rh	190	23	-	-	HYPH
cord-322166-ajolu2rh	190	24	inducing	induce	VBG
cord-322166-ajolu2rh	190	25	ligand	ligand	NN
cord-322166-ajolu2rh	190	26	-	-	HYPH
cord-322166-ajolu2rh	190	27	induced	induce	VBN
cord-322166-ajolu2rh	190	28	apoptosis	apoptosis	NN
cord-322166-ajolu2rh	190	29	in	in	IN
cord-322166-ajolu2rh	190	30	Jurkat	Jurkat	NNP
cord-322166-ajolu2rh	190	31	T	T	NNP
cord-322166-ajolu2rh	190	32	cells	cell	NNS
cord-322166-ajolu2rh	190	33	(	(	-LRB-
cord-322166-ajolu2rh	190	34	Lee	Lee	NNP
cord-322166-ajolu2rh	190	35	D	D	NNP
cord-322166-ajolu2rh	190	36	C	C	NNP
cord-322166-ajolu2rh	190	37	,	,	,
cord-322166-ajolu2rh	190	38	et	et	NNP
cord-322166-ajolu2rh	190	39	al	al	NNP
cord-322166-ajolu2rh	190	40	.	.	NNP
cord-322166-ajolu2rh	190	41	,	,	,
cord-322166-ajolu2rh	190	42	2005	2005	CD
cord-322166-ajolu2rh	190	43	;	;	:
cord-322166-ajolu2rh	190	44	Mok	Mok	NNP
cord-322166-ajolu2rh	190	45	C	C	NNP
cord-322166-ajolu2rh	190	46	K	K	NNP
cord-322166-ajolu2rh	190	47	,	,	,
cord-322166-ajolu2rh	190	48	et	et	NNP
cord-322166-ajolu2rh	190	49	al	al	NNP
cord-322166-ajolu2rh	190	50	.	.	NNP
cord-322166-ajolu2rh	190	51	,	,	,
cord-322166-ajolu2rh	190	52	2007	2007	CD
cord-322166-ajolu2rh	190	53	)	)	-RRB-
cord-322166-ajolu2rh	190	54	.	.	.
cord-322166-ajolu2rh	191	1	However	however	RB
cord-322166-ajolu2rh	191	2	,	,	,
cord-322166-ajolu2rh	191	3	in	in	IN
cord-322166-ajolu2rh	191	4	contrast	contrast	NN
cord-322166-ajolu2rh	191	5	with	with	IN
cord-322166-ajolu2rh	191	6	findings	finding	NNS
cord-322166-ajolu2rh	191	7	from	from	IN
cord-322166-ajolu2rh	191	8	human	human	JJ
cord-322166-ajolu2rh	191	9	macrophage	macrophage	NN
cord-322166-ajolu2rh	191	10	studies	study	NNS
cord-322166-ajolu2rh	191	11	,	,	,
cord-322166-ajolu2rh	191	12	differences	difference	NNS
cord-322166-ajolu2rh	191	13	between	between	IN
cord-322166-ajolu2rh	191	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	191	15	and	and	CC
cord-322166-ajolu2rh	191	16	H1N1	H1N1	NNP
cord-322166-ajolu2rh	191	17	induced	induce	VBD
cord-322166-ajolu2rh	191	18	secretion	secretion	NN
cord-322166-ajolu2rh	191	19	of	of	IN
cord-322166-ajolu2rh	191	20	pro	pro	JJ
cord-322166-ajolu2rh	191	21	-	-	JJ
cord-322166-ajolu2rh	191	22	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	191	23	cytokines	cytokine	NNS
cord-322166-ajolu2rh	191	24	TNF	TNF	NNP
cord-322166-ajolu2rh	191	25	-	-	HYPH
cord-322166-ajolu2rh	191	26	α	α	NNP
cord-322166-ajolu2rh	191	27	and	and	CC
cord-322166-ajolu2rh	191	28	IP-10	IP-10	NNP
cord-322166-ajolu2rh	191	29	were	be	VBD
cord-322166-ajolu2rh	191	30	less	less	RBR
cord-322166-ajolu2rh	191	31	pronounced	pronounced	JJ
cord-322166-ajolu2rh	191	32	in	in	IN
cord-322166-ajolu2rh	191	33	human	human	JJ
cord-322166-ajolu2rh	191	34	plasmacytoid	plasmacytoid	NN
cord-322166-ajolu2rh	191	35	dendritic	dendritic	JJ
cord-322166-ajolu2rh	191	36	cells	cell	NNS
cord-322166-ajolu2rh	191	37	,	,	,
cord-322166-ajolu2rh	191	38	although	although	IN
cord-322166-ajolu2rh	191	39	H5N1	H5N1	NNP
cord-322166-ajolu2rh	191	40	also	also	RB
cord-322166-ajolu2rh	191	41	showed	show	VBD
cord-322166-ajolu2rh	191	42	higher	high	JJR
cord-322166-ajolu2rh	191	43	expression	expression	NN
cord-322166-ajolu2rh	191	44	of	of	IN
cord-322166-ajolu2rh	191	45	IFN	IFN	NNP
cord-322166-ajolu2rh	191	46	-	-	HYPH
cord-322166-ajolu2rh	191	47	α	α	NNP
cord-322166-ajolu2rh	191	48	than	than	IN
cord-322166-ajolu2rh	191	49	did	do	VBD
cord-322166-ajolu2rh	191	50	H1N1	H1N1	NNP
cord-322166-ajolu2rh	191	51	and	and	CC
cord-322166-ajolu2rh	191	52	H3N2	H3N2	NNP
cord-322166-ajolu2rh	191	53	viruses	virus	NNS
cord-322166-ajolu2rh	192	1	(	(	-LRB-
cord-322166-ajolu2rh	192	2	Sandbulte	Sandbulte	NNP
cord-322166-ajolu2rh	192	3	M	M	NNP
cord-322166-ajolu2rh	192	4	R	R	NNP
cord-322166-ajolu2rh	192	5	,	,	,
cord-322166-ajolu2rh	192	6	et	et	NNP
cord-322166-ajolu2rh	192	7	al	al	NNP
cord-322166-ajolu2rh	192	8	.	.	NNP
cord-322166-ajolu2rh	192	9	,	,	,
cord-322166-ajolu2rh	192	10	2008	2008	CD
cord-322166-ajolu2rh	192	11	)	)	-RRB-
cord-322166-ajolu2rh	192	12	.	.	.
cord-322166-ajolu2rh	193	1	Despite	despite	IN
cord-322166-ajolu2rh	193	2	significant	significant	JJ
cord-322166-ajolu2rh	193	3	diversity	diversity	NN
cord-322166-ajolu2rh	193	4	in	in	IN
cord-322166-ajolu2rh	193	5	the	the	DT
cord-322166-ajolu2rh	193	6	induction	induction	NN
cord-322166-ajolu2rh	193	7	profile	profile	NN
cord-322166-ajolu2rh	193	8	of	of	IN
cord-322166-ajolu2rh	193	9	pro	pro	JJ
cord-322166-ajolu2rh	193	10	-	-	JJ
cord-322166-ajolu2rh	193	11	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	193	12	cytokines	cytokine	NNS
cord-322166-ajolu2rh	193	13	and	and	CC
cord-322166-ajolu2rh	193	14	chemokines	chemokine	NNS
cord-322166-ajolu2rh	193	15	in	in	IN
cord-322166-ajolu2rh	193	16	H5N1	H5N1	NNP
cord-322166-ajolu2rh	193	17	as	as	IN
cord-322166-ajolu2rh	193	18	compared	compare	VBN
cord-322166-ajolu2rh	193	19	with	with	IN
cord-322166-ajolu2rh	193	20	seasonal	seasonal	JJ
cord-322166-ajolu2rh	193	21	H1N1	H1N1	NNP
cord-322166-ajolu2rh	193	22	,	,	,
cord-322166-ajolu2rh	193	23	the	the	DT
cord-322166-ajolu2rh	193	24	magnitude	magnitude	NN
cord-322166-ajolu2rh	193	25	of	of	IN
cord-322166-ajolu2rh	193	26	the	the	DT
cord-322166-ajolu2rh	193	27	pro	pro	JJ
cord-322166-ajolu2rh	193	28	-	-	JJ
cord-322166-ajolu2rh	193	29	inflammatory	inflammatory	JJ
cord-322166-ajolu2rh	193	30	response	response	NN
cord-322166-ajolu2rh	193	31	triggered	trigger	VBN
cord-322166-ajolu2rh	193	32	by	by	IN
cord-322166-ajolu2rh	193	33	H5N1	H5N1	NNP
cord-322166-ajolu2rh	193	34	is	be	VBZ
cord-322166-ajolu2rh	193	35	also	also	RB
cord-322166-ajolu2rh	193	36	much	much	RB
cord-322166-ajolu2rh	193	37	stronger	strong	JJR
cord-322166-ajolu2rh	193	38	than	than	IN
cord-322166-ajolu2rh	193	39	that	that	DT
cord-322166-ajolu2rh	193	40	triggered	trigger	VBN
cord-322166-ajolu2rh	193	41	by	by	IN
cord-322166-ajolu2rh	193	42	other	other	JJ
cord-322166-ajolu2rh	193	43	human	human	JJ
cord-322166-ajolu2rh	193	44	influenza	influenza	NN
cord-322166-ajolu2rh	193	45	viruses	virus	NNS
cord-322166-ajolu2rh	193	46	(	(	-LRB-
cord-322166-ajolu2rh	193	47	Bel	Bel	NNP
cord-322166-ajolu2rh	193	48	M	M	NNP
cord-322166-ajolu2rh	193	49	,	,	,
cord-322166-ajolu2rh	193	50	et	et	NNP
cord-322166-ajolu2rh	193	51	al	al	NNP
cord-322166-ajolu2rh	193	52	.	.	NNP
cord-322166-ajolu2rh	193	53	,	,	,
cord-322166-ajolu2rh	193	54	2011	2011	CD
cord-322166-ajolu2rh	193	55	;	;	:
cord-322166-ajolu2rh	193	56	Sandbulte	Sandbulte	NNP
cord-322166-ajolu2rh	193	57	M	M	NNP
cord-322166-ajolu2rh	193	58	R	R	NNP
cord-322166-ajolu2rh	193	59	,	,	,
cord-322166-ajolu2rh	193	60	et	et	NNP
cord-322166-ajolu2rh	193	61	al	al	NNP
cord-322166-ajolu2rh	193	62	.	.	NNP
cord-322166-ajolu2rh	193	63	,	,	,
cord-322166-ajolu2rh	193	64	2008	2008	CD
cord-322166-ajolu2rh	193	65	;	;	:
cord-322166-ajolu2rh	193	66	Tolnay	Tolnay	NNP
cord-322166-ajolu2rh	193	67	A	A	NNP
cord-322166-ajolu2rh	193	68	E	e	NN
cord-322166-ajolu2rh	193	69	,	,	,
cord-322166-ajolu2rh	193	70	et	et	NNP
cord-322166-ajolu2rh	193	71	al	al	NNP
cord-322166-ajolu2rh	193	72	.	.	NNP
cord-322166-ajolu2rh	193	73	,	,	,
cord-322166-ajolu2rh	193	74	2010	2010	CD
cord-322166-ajolu2rh	193	75	;	;	:
cord-322166-ajolu2rh	193	76	Zeng	Zeng	NNP
cord-322166-ajolu2rh	193	77	H	H	NNP
cord-322166-ajolu2rh	193	78	,	,	,
cord-322166-ajolu2rh	193	79	et	et	NNP
cord-322166-ajolu2rh	193	80	al	al	NNP
cord-322166-ajolu2rh	193	81	.	.	NNP
cord-322166-ajolu2rh	193	82	,	,	,
cord-322166-ajolu2rh	193	83	2007	2007	CD
cord-322166-ajolu2rh	193	84	)	)	-RRB-
cord-322166-ajolu2rh	193	85	.	.	.
cord-322166-ajolu2rh	194	1	The	the	DT
cord-322166-ajolu2rh	194	2	cytokine	cytokine	NN
cord-322166-ajolu2rh	194	3	storm	storm	NN
cord-322166-ajolu2rh	194	4	caused	cause	VBN
cord-322166-ajolu2rh	194	5	by	by	IN
cord-322166-ajolu2rh	194	6	the	the	DT
cord-322166-ajolu2rh	194	7	induction	induction	NN
cord-322166-ajolu2rh	194	8	(	(	-LRB-
cord-322166-ajolu2rh	194	9	or	or	CC
cord-322166-ajolu2rh	194	10	suppression	suppression	NN
cord-322166-ajolu2rh	194	11	)	)	-RRB-
cord-322166-ajolu2rh	194	12	of	of	IN
cord-322166-ajolu2rh	194	13	gene	gene	NN
cord-322166-ajolu2rh	194	14	expression	expression	NN
cord-322166-ajolu2rh	194	15	and	and	CC
cord-322166-ajolu2rh	194	16	signaling	signal	VBG
cord-322166-ajolu2rh	194	17	pathways	pathway	NNS
cord-322166-ajolu2rh	194	18	9	9	CD
cord-322166-ajolu2rh	194	19	illustrates	illustrate	VBZ
cord-322166-ajolu2rh	194	20	the	the	DT
cord-322166-ajolu2rh	194	21	extreme	extreme	JJ
cord-322166-ajolu2rh	194	22	and	and	CC
cord-322166-ajolu2rh	194	23	serious	serious	JJ
cord-322166-ajolu2rh	194	24	consequences	consequence	NNS
cord-322166-ajolu2rh	194	25	of	of	IN
cord-322166-ajolu2rh	194	26	H5N1	H5N1	NNP
cord-322166-ajolu2rh	194	27	infection	infection	NN
cord-322166-ajolu2rh	194	28	.	.	.
cord-322166-ajolu2rh	195	1	Therefore	therefore	RB
cord-322166-ajolu2rh	195	2	,	,	,
cord-322166-ajolu2rh	195	3	identifying	identify	VBG
cord-322166-ajolu2rh	195	4	these	these	DT
cord-322166-ajolu2rh	195	5	pathways	pathway	NNS
cord-322166-ajolu2rh	195	6	will	will	MD
cord-322166-ajolu2rh	195	7	help	help	VB
cord-322166-ajolu2rh	195	8	to	to	TO
cord-322166-ajolu2rh	195	9	find	find	VB
cord-322166-ajolu2rh	195	10	effective	effective	JJ
cord-322166-ajolu2rh	195	11	methods	method	NNS
cord-322166-ajolu2rh	195	12	of	of	IN
cord-322166-ajolu2rh	195	13	fighting	fight	VBG
cord-322166-ajolu2rh	195	14	this	this	DT
cord-322166-ajolu2rh	195	15	highly	highly	RB
cord-322166-ajolu2rh	195	16	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	195	17	virus	virus	NN
cord-322166-ajolu2rh	195	18	.	.	.
cord-322166-ajolu2rh	196	1	Although	although	IN
cord-322166-ajolu2rh	196	2	high	high	JJ
cord-322166-ajolu2rh	196	3	virus	virus	NN
cord-322166-ajolu2rh	196	4	titers	titer	NNS
cord-322166-ajolu2rh	196	5	were	be	VBD
cord-322166-ajolu2rh	196	6	often	often	RB
cord-322166-ajolu2rh	196	7	detected	detect	VBN
cord-322166-ajolu2rh	196	8	in	in	IN
cord-322166-ajolu2rh	196	9	many	many	JJ
cord-322166-ajolu2rh	196	10	tissues	tissue	NNS
cord-322166-ajolu2rh	196	11	and	and	CC
cord-322166-ajolu2rh	196	12	blood	blood	NN
cord-322166-ajolu2rh	196	13	during	during	IN
cord-322166-ajolu2rh	196	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	196	15	infections	infection	NNS
cord-322166-ajolu2rh	196	16	,	,	,
cord-322166-ajolu2rh	196	17	throat	throat	NN
cord-322166-ajolu2rh	196	18	swabs	swab	NNS
cord-322166-ajolu2rh	196	19	and	and	CC
cord-322166-ajolu2rh	196	20	lower	low	JJR
cord-322166-ajolu2rh	196	21	respiratory	respiratory	JJ
cord-322166-ajolu2rh	196	22	samples	sample	NNS
cord-322166-ajolu2rh	196	23	are	be	VBP
cord-322166-ajolu2rh	196	24	the	the	DT
cord-322166-ajolu2rh	196	25	preferred	preferred	JJ
cord-322166-ajolu2rh	196	26	and	and	CC
cord-322166-ajolu2rh	196	27	recommended	recommend	VBN
cord-322166-ajolu2rh	196	28	specimen	specimen	NN
cord-322166-ajolu2rh	196	29	for	for	IN
cord-322166-ajolu2rh	196	30	virus	virus	NN
cord-322166-ajolu2rh	196	31	detection	detection	NN
cord-322166-ajolu2rh	196	32	.	.	.
cord-322166-ajolu2rh	197	1	H5N1	H5N1	NNP
cord-322166-ajolu2rh	197	2	virus	virus	NN
cord-322166-ajolu2rh	197	3	titers	titer	NNS
cord-322166-ajolu2rh	197	4	are	be	VBP
cord-322166-ajolu2rh	197	5	higher	high	JJR
cord-322166-ajolu2rh	197	6	in	in	IN
cord-322166-ajolu2rh	197	7	pharyngeal	pharyngeal	JJ
cord-322166-ajolu2rh	197	8	and	and	CC
cord-322166-ajolu2rh	197	9	bronchial	bronchial	JJ
cord-322166-ajolu2rh	197	10	alveolar	alveolar	NN
cord-322166-ajolu2rh	197	11	lavages	lavage	NNS
cord-322166-ajolu2rh	197	12	and	and	CC
cord-322166-ajolu2rh	197	13	tracheal	tracheal	JJ
cord-322166-ajolu2rh	197	14	aspirates	aspirate	NNS
cord-322166-ajolu2rh	197	15	than	than	IN
cord-322166-ajolu2rh	197	16	in	in	IN
cord-322166-ajolu2rh	197	17	nasal	nasal	JJ
cord-322166-ajolu2rh	197	18	epithelial	epithelial	JJ
cord-322166-ajolu2rh	197	19	cells	cell	NNS
cord-322166-ajolu2rh	197	20	or	or	CC
cord-322166-ajolu2rh	197	21	aspirates	aspirate	NNS
cord-322166-ajolu2rh	197	22	(	(	-LRB-
cord-322166-ajolu2rh	197	23	Beigel	Beigel	NNP
cord-322166-ajolu2rh	197	24	J	J	NNP
cord-322166-ajolu2rh	197	25	H	H	NNP
cord-322166-ajolu2rh	197	26	,	,	,
cord-322166-ajolu2rh	197	27	et	et	NNP
cord-322166-ajolu2rh	197	28	al	al	NNP
cord-322166-ajolu2rh	197	29	.	.	NNP
cord-322166-ajolu2rh	197	30	,	,	,
cord-322166-ajolu2rh	197	31	2005	2005	CD
cord-322166-ajolu2rh	197	32	;	;	:
cord-322166-ajolu2rh	197	33	de	de	NNP
cord-322166-ajolu2rh	197	34	Jong	Jong	NNP
cord-322166-ajolu2rh	197	35	M	M	NNP
cord-322166-ajolu2rh	197	36	D	D	NNP
cord-322166-ajolu2rh	197	37	,	,	,
cord-322166-ajolu2rh	197	38	et	et	NNP
cord-322166-ajolu2rh	197	39	al	al	NNP
cord-322166-ajolu2rh	197	40	.	.	NNP
cord-322166-ajolu2rh	197	41	,	,	,
cord-322166-ajolu2rh	197	42	2006	2006	CD
cord-322166-ajolu2rh	197	43	;	;	:
cord-322166-ajolu2rh	197	44	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	197	45	M	M	NNP
cord-322166-ajolu2rh	197	46	J	J	NNP
cord-322166-ajolu2rh	197	47	,	,	,
cord-322166-ajolu2rh	197	48	2011	2011	CD
cord-322166-ajolu2rh	197	49	;	;	:
cord-322166-ajolu2rh	197	50	Wang	Wang	NNP
cord-322166-ajolu2rh	197	51	H	H	NNP
cord-322166-ajolu2rh	197	52	,	,	,
cord-322166-ajolu2rh	197	53	et	et	NNP
cord-322166-ajolu2rh	197	54	al	al	NNP
cord-322166-ajolu2rh	197	55	.	.	NNP
cord-322166-ajolu2rh	197	56	,	,	,
cord-322166-ajolu2rh	197	57	2009	2009	CD
cord-322166-ajolu2rh	197	58	;	;	:
cord-322166-ajolu2rh	197	59	WHO	who	WP
cord-322166-ajolu2rh	197	60	,	,	,
cord-322166-ajolu2rh	197	61	2008	2008	CD
cord-322166-ajolu2rh	197	62	;	;	:
cord-322166-ajolu2rh	197	63	Yu	Yu	NNP
cord-322166-ajolu2rh	197	64	W	W	NNP
cord-322166-ajolu2rh	197	65	C	C	NNP
cord-322166-ajolu2rh	197	66	,	,	,
cord-322166-ajolu2rh	197	67	et	et	NNP
cord-322166-ajolu2rh	197	68	al	al	NNP
cord-322166-ajolu2rh	197	69	.	.	NNP
cord-322166-ajolu2rh	197	70	,	,	,
cord-322166-ajolu2rh	197	71	2011	2011	CD
cord-322166-ajolu2rh	197	72	)	)	-RRB-
cord-322166-ajolu2rh	197	73	.	.	.
cord-322166-ajolu2rh	198	1	Patient	patient	JJ
cord-322166-ajolu2rh	198	2	samples	sample	NNS
cord-322166-ajolu2rh	198	3	should	should	MD
cord-322166-ajolu2rh	198	4	be	be	VB
cord-322166-ajolu2rh	198	5	stored	store	VBN
cord-322166-ajolu2rh	198	6	carefully	carefully	RB
cord-322166-ajolu2rh	198	7	(	(	-LRB-
cord-322166-ajolu2rh	198	8	e.g.	e.g.	RB
cord-322166-ajolu2rh	198	9	,	,	,
cord-322166-ajolu2rh	198	10	kept	keep	VBD
cord-322166-ajolu2rh	198	11	on	on	IN
cord-322166-ajolu2rh	198	12	ice	ice	NN
cord-322166-ajolu2rh	198	13	)	)	-RRB-
cord-322166-ajolu2rh	198	14	before	before	IN
cord-322166-ajolu2rh	198	15	testing	testing	NN
cord-322166-ajolu2rh	199	1	and	and	CC
cord-322166-ajolu2rh	199	2	it	-PRON-	PRP
cord-322166-ajolu2rh	199	3	is	be	VBZ
cord-322166-ajolu2rh	199	4	recommended	recommend	VBN
cord-322166-ajolu2rh	199	5	to	to	TO
cord-322166-ajolu2rh	199	6	use	use	VB
cord-322166-ajolu2rh	199	7	the	the	DT
cord-322166-ajolu2rh	199	8	specimens	specimen	NNS
cord-322166-ajolu2rh	199	9	as	as	RB
cord-322166-ajolu2rh	199	10	soon	soon	RB
cord-322166-ajolu2rh	199	11	as	as	IN
cord-322166-ajolu2rh	199	12	possible	possible	JJ
cord-322166-ajolu2rh	199	13	(	(	-LRB-
cord-322166-ajolu2rh	199	14	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	199	15	M	M	NNP
cord-322166-ajolu2rh	199	16	J	J	NNP
cord-322166-ajolu2rh	199	17	,	,	,
cord-322166-ajolu2rh	199	18	2011	2011	CD
cord-322166-ajolu2rh	199	19	)	)	-RRB-
cord-322166-ajolu2rh	199	20	.	.	.
cord-322166-ajolu2rh	200	1	Diagnosis	diagnosis	NN
cord-322166-ajolu2rh	200	2	of	of	IN
cord-322166-ajolu2rh	200	3	H5N1	H5N1	NNP
cord-322166-ajolu2rh	200	4	influenza	influenza	NN
cord-322166-ajolu2rh	200	5	infection	infection	NN
cord-322166-ajolu2rh	200	6	requires	require	VBZ
cord-322166-ajolu2rh	200	7	a	a	DT
cord-322166-ajolu2rh	200	8	systematic	systematic	JJ
cord-322166-ajolu2rh	200	9	analysis	analysis	NN
cord-322166-ajolu2rh	200	10	.	.	.
cord-322166-ajolu2rh	201	1	A	a	DT
cord-322166-ajolu2rh	201	2	history	history	NN
cord-322166-ajolu2rh	201	3	of	of	IN
cord-322166-ajolu2rh	201	4	recent	recent	JJ
cord-322166-ajolu2rh	201	5	of	of	IN
cord-322166-ajolu2rh	201	6	travel	travel	NN
cord-322166-ajolu2rh	201	7	and	and	CC
cord-322166-ajolu2rh	201	8	personal	personal	JJ
cord-322166-ajolu2rh	201	9	contacts	contact	NNS
cord-322166-ajolu2rh	201	10	as	as	RB
cord-322166-ajolu2rh	201	11	well	well	RB
cord-322166-ajolu2rh	201	12	as	as	IN
cord-322166-ajolu2rh	201	13	clinical	clinical	JJ
cord-322166-ajolu2rh	201	14	symptoms	symptom	NNS
cord-322166-ajolu2rh	201	15	and	and	CC
cord-322166-ajolu2rh	201	16	many	many	JJ
cord-322166-ajolu2rh	201	17	other	other	JJ
cord-322166-ajolu2rh	201	18	factors	factor	NNS
cord-322166-ajolu2rh	201	19	should	should	MD
cord-322166-ajolu2rh	201	20	be	be	VB
cord-322166-ajolu2rh	201	21	considered	consider	VBN
cord-322166-ajolu2rh	201	22	(	(	-LRB-
cord-322166-ajolu2rh	201	23	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	201	24	M	M	NNP
cord-322166-ajolu2rh	201	25	J	J	NNP
cord-322166-ajolu2rh	201	26	,	,	,
cord-322166-ajolu2rh	201	27	2011	2011	CD
cord-322166-ajolu2rh	201	28	)	)	-RRB-
cord-322166-ajolu2rh	201	29	.	.	.
cord-322166-ajolu2rh	202	1	Many	many	JJ
cord-322166-ajolu2rh	202	2	rapid	rapid	JJ
cord-322166-ajolu2rh	202	3	diagnostic	diagnostic	JJ
cord-322166-ajolu2rh	202	4	techniques	technique	NNS
cord-322166-ajolu2rh	202	5	can	can	MD
cord-322166-ajolu2rh	202	6	detect	detect	VB
cord-322166-ajolu2rh	202	7	seasonal	seasonal	JJ
cord-322166-ajolu2rh	202	8	influenza	influenza	NN
cord-322166-ajolu2rh	202	9	in	in	IN
cord-322166-ajolu2rh	202	10	clinical	clinical	JJ
cord-322166-ajolu2rh	202	11	specimens	specimen	NNS
cord-322166-ajolu2rh	202	12	,	,	,
cord-322166-ajolu2rh	202	13	but	but	CC
cord-322166-ajolu2rh	202	14	the	the	DT
cord-322166-ajolu2rh	202	15	rapid	rapid	JJ
cord-322166-ajolu2rh	202	16	antigen	antigen	NN
cord-322166-ajolu2rh	202	17	tests	test	NNS
cord-322166-ajolu2rh	202	18	designed	design	VBN
cord-322166-ajolu2rh	202	19	to	to	TO
cord-322166-ajolu2rh	202	20	detect	detect	VB
cord-322166-ajolu2rh	202	21	seasonal	seasonal	JJ
cord-322166-ajolu2rh	202	22	strains	strain	NNS
cord-322166-ajolu2rh	202	23	of	of	IN
cord-322166-ajolu2rh	202	24	influenza	influenza	NN
cord-322166-ajolu2rh	202	25	are	be	VBP
cord-322166-ajolu2rh	202	26	less	less	RBR
cord-322166-ajolu2rh	202	27	effective	effective	JJ
cord-322166-ajolu2rh	202	28	for	for	IN
cord-322166-ajolu2rh	202	29	H5N1	H5N1	NNP
cord-322166-ajolu2rh	202	30	(	(	-LRB-
cord-322166-ajolu2rh	202	31	Beigel	Beigel	NNP
cord-322166-ajolu2rh	202	32	J	J	NNP
cord-322166-ajolu2rh	202	33	H	H	NNP
cord-322166-ajolu2rh	202	34	,	,	,
cord-322166-ajolu2rh	202	35	et	et	NNP
cord-322166-ajolu2rh	202	36	al	al	NNP
cord-322166-ajolu2rh	202	37	.	.	NNP
cord-322166-ajolu2rh	202	38	,	,	,
cord-322166-ajolu2rh	202	39	2005	2005	CD
cord-322166-ajolu2rh	202	40	)	)	-RRB-
cord-322166-ajolu2rh	202	41	.	.	.
cord-322166-ajolu2rh	203	1	In	in	IN
cord-322166-ajolu2rh	203	2	addition	addition	NN
cord-322166-ajolu2rh	203	3	,	,	,
cord-322166-ajolu2rh	203	4	since	since	IN
cord-322166-ajolu2rh	203	5	the	the	DT
cord-322166-ajolu2rh	203	6	clinical	clinical	JJ
cord-322166-ajolu2rh	203	7	presentation	presentation	NN
cord-322166-ajolu2rh	203	8	of	of	IN
cord-322166-ajolu2rh	203	9	numerous	numerous	JJ
cord-322166-ajolu2rh	203	10	illnesses	illness	NNS
cord-322166-ajolu2rh	203	11	may	may	MD
cord-322166-ajolu2rh	203	12	resemble	resemble	VB
cord-322166-ajolu2rh	203	13	influenza	influenza	NN
cord-322166-ajolu2rh	203	14	,	,	,
cord-322166-ajolu2rh	203	15	and	and	CC
cord-322166-ajolu2rh	203	16	the	the	DT
cord-322166-ajolu2rh	203	17	many	many	JJ
cord-322166-ajolu2rh	203	18	different	different	JJ
cord-322166-ajolu2rh	203	19	influenza	influenza	NN
cord-322166-ajolu2rh	203	20	virus	virus	NN
cord-322166-ajolu2rh	203	21	share	share	VBP
cord-322166-ajolu2rh	203	22	a	a	DT
cord-322166-ajolu2rh	203	23	number	number	NN
cord-322166-ajolu2rh	203	24	of	of	IN
cord-322166-ajolu2rh	203	25	clinical	clinical	JJ
cord-322166-ajolu2rh	203	26	features	feature	NNS
cord-322166-ajolu2rh	203	27	,	,	,
cord-322166-ajolu2rh	203	28	diagnosis	diagnosis	NN
cord-322166-ajolu2rh	203	29	of	of	IN
cord-322166-ajolu2rh	203	30	a	a	DT
cord-322166-ajolu2rh	203	31	particular	particular	JJ
cord-322166-ajolu2rh	203	32	subtype	subtype	NN
cord-322166-ajolu2rh	203	33	can	can	MD
cord-322166-ajolu2rh	203	34	only	only	RB
cord-322166-ajolu2rh	203	35	be	be	VB
cord-322166-ajolu2rh	203	36	accurately	accurately	RB
cord-322166-ajolu2rh	203	37	identified	identify	VBN
cord-322166-ajolu2rh	203	38	by	by	IN
cord-322166-ajolu2rh	203	39	laboratory	laboratory	NN
cord-322166-ajolu2rh	203	40	tests	test	NNS
cord-322166-ajolu2rh	203	41	(	(	-LRB-
cord-322166-ajolu2rh	203	42	Shaw	Shaw	NNP
cord-322166-ajolu2rh	203	43	M	M	NNP
cord-322166-ajolu2rh	203	44	,	,	,
cord-322166-ajolu2rh	203	45	et	et	NNP
cord-322166-ajolu2rh	203	46	al	al	NNP
cord-322166-ajolu2rh	203	47	.	.	NNP
cord-322166-ajolu2rh	203	48	,	,	,
cord-322166-ajolu2rh	203	49	1992	1992	CD
cord-322166-ajolu2rh	203	50	)	)	-RRB-
cord-322166-ajolu2rh	203	51	.	.	.
cord-322166-ajolu2rh	204	1	Sensitive	sensitive	JJ
cord-322166-ajolu2rh	204	2	and	and	CC
cord-322166-ajolu2rh	204	3	specific	specific	JJ
cord-322166-ajolu2rh	204	4	tests	test	NNS
cord-322166-ajolu2rh	204	5	are	be	VBP
cord-322166-ajolu2rh	204	6	needed	need	VBN
cord-322166-ajolu2rh	204	7	,	,	,
cord-322166-ajolu2rh	204	8	but	but	CC
cord-322166-ajolu2rh	204	9	remain	remain	VB
cord-322166-ajolu2rh	204	10	to	to	TO
cord-322166-ajolu2rh	204	11	be	be	VB
cord-322166-ajolu2rh	204	12	developed	develop	VBN
cord-322166-ajolu2rh	204	13	.	.	.
cord-322166-ajolu2rh	205	1	At	at	IN
cord-322166-ajolu2rh	205	2	this	this	DT
cord-322166-ajolu2rh	205	3	time	time	NN
cord-322166-ajolu2rh	205	4	,	,	,
cord-322166-ajolu2rh	205	5	laboratory	laboratory	NN
cord-322166-ajolu2rh	205	6	diagnosis	diagnosis	NN
cord-322166-ajolu2rh	205	7	for	for	IN
cord-322166-ajolu2rh	205	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	205	9	includes	include	VBZ
cord-322166-ajolu2rh	205	10	virus	virus	NN
cord-322166-ajolu2rh	205	11	culture	culture	NN
cord-322166-ajolu2rh	205	12	,	,	,
cord-322166-ajolu2rh	205	13	rapid	rapid	JJ
cord-322166-ajolu2rh	205	14	antigen	antigen	NN
cord-322166-ajolu2rh	205	15	detection	detection	NN
cord-322166-ajolu2rh	205	16	,	,	,
cord-322166-ajolu2rh	205	17	and	and	CC
cord-322166-ajolu2rh	205	18	viral	viral	JJ
cord-322166-ajolu2rh	205	19	nucleic	nucleic	JJ
cord-322166-ajolu2rh	205	20	acid	acid	NN
cord-322166-ajolu2rh	205	21	amplification	amplification	NN
cord-322166-ajolu2rh	205	22	methods	method	NNS
cord-322166-ajolu2rh	205	23	in	in	IN
cord-322166-ajolu2rh	205	24	addition	addition	NN
cord-322166-ajolu2rh	205	25	to	to	IN
cord-322166-ajolu2rh	205	26	serology	serology	NN
cord-322166-ajolu2rh	205	27	(	(	-LRB-
cord-322166-ajolu2rh	205	28	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	205	29	M	M	NNP
cord-322166-ajolu2rh	205	30	J	J	NNP
cord-322166-ajolu2rh	205	31	,	,	,
cord-322166-ajolu2rh	205	32	2011	2011	CD
cord-322166-ajolu2rh	205	33	)	)	-RRB-
cord-322166-ajolu2rh	205	34	.	.	.
cord-322166-ajolu2rh	206	1	All	all	PDT
cord-322166-ajolu2rh	206	2	these	these	DT
cord-322166-ajolu2rh	206	3	methods	method	NNS
cord-322166-ajolu2rh	206	4	have	have	VBP
cord-322166-ajolu2rh	206	5	advantages	advantage	NNS
cord-322166-ajolu2rh	206	6	and	and	CC
cord-322166-ajolu2rh	206	7	disadvantages	disadvantage	NNS
cord-322166-ajolu2rh	206	8	.	.	.
cord-322166-ajolu2rh	207	1	For	for	IN
cord-322166-ajolu2rh	207	2	effective	effective	JJ
cord-322166-ajolu2rh	207	3	surveillance	surveillance	NN
cord-322166-ajolu2rh	207	4	,	,	,
cord-322166-ajolu2rh	207	5	the	the	DT
cord-322166-ajolu2rh	207	6	proper	proper	JJ
cord-322166-ajolu2rh	207	7	time	time	NN
cord-322166-ajolu2rh	207	8	to	to	TO
cord-322166-ajolu2rh	207	9	apply	apply	VB
cord-322166-ajolu2rh	207	10	a	a	DT
cord-322166-ajolu2rh	207	11	particular	particular	JJ
cord-322166-ajolu2rh	207	12	diagnostic	diagnostic	JJ
cord-322166-ajolu2rh	207	13	methods	method	NNS
cord-322166-ajolu2rh	207	14	or	or	CC
cord-322166-ajolu2rh	207	15	combination	combination	NN
cord-322166-ajolu2rh	207	16	of	of	IN
cord-322166-ajolu2rh	207	17	methods	method	NNS
cord-322166-ajolu2rh	207	18	must	must	MD
cord-322166-ajolu2rh	207	19	be	be	VB
cord-322166-ajolu2rh	207	20	carefully	carefully	RB
cord-322166-ajolu2rh	207	21	considered	consider	VBN
cord-322166-ajolu2rh	207	22	,	,	,
cord-322166-ajolu2rh	207	23	particularly	particularly	RB
cord-322166-ajolu2rh	207	24	at	at	IN
cord-322166-ajolu2rh	207	25	the	the	DT
cord-322166-ajolu2rh	207	26	pre	pre	JJ
cord-322166-ajolu2rh	207	27	-	-	JJ
cord-322166-ajolu2rh	207	28	pandemic	pandemic	JJ
cord-322166-ajolu2rh	207	29	period	period	NN
cord-322166-ajolu2rh	207	30	of	of	IN
cord-322166-ajolu2rh	207	31	H5N1	H5N1	NNP
cord-322166-ajolu2rh	207	32	spread	spread	VBD
cord-322166-ajolu2rh	207	33	.	.	.
cord-322166-ajolu2rh	208	1	Viral	viral	JJ
cord-322166-ajolu2rh	208	2	nucleic	nucleic	JJ
cord-322166-ajolu2rh	208	3	acid	acid	NN
cord-322166-ajolu2rh	208	4	amplification	amplification	NN
cord-322166-ajolu2rh	208	5	,	,	,
cord-322166-ajolu2rh	208	6	for	for	IN
cord-322166-ajolu2rh	208	7	example	example	NN
cord-322166-ajolu2rh	208	8	reversetranscription	reversetranscription	NN
cord-322166-ajolu2rh	208	9	polymerase	polymerase	NN
cord-322166-ajolu2rh	208	10	chain	chain	NN
cord-322166-ajolu2rh	208	11	reaction	reaction	NN
cord-322166-ajolu2rh	208	12	(	(	-LRB-
cord-322166-ajolu2rh	208	13	RT	RT	NNP
cord-322166-ajolu2rh	208	14	-	-	HYPH
cord-322166-ajolu2rh	208	15	PCR	PCR	NNP
cord-322166-ajolu2rh	208	16	)	)	-RRB-
cord-322166-ajolu2rh	208	17	,	,	,
cord-322166-ajolu2rh	208	18	is	be	VBZ
cord-322166-ajolu2rh	208	19	highly	highly	RB
cord-322166-ajolu2rh	208	20	sensitive	sensitive	JJ
cord-322166-ajolu2rh	208	21	.	.	.
cord-322166-ajolu2rh	209	1	The	the	DT
cord-322166-ajolu2rh	209	2	human	human	JJ
cord-322166-ajolu2rh	209	3	H5N1	H5N1	NNP
cord-322166-ajolu2rh	209	4	virus	virus	NN
cord-322166-ajolu2rh	209	5	outbreaks	outbreak	NNS
cord-322166-ajolu2rh	209	6	in	in	IN
cord-322166-ajolu2rh	209	7	Hong	Hong	NNP
cord-322166-ajolu2rh	209	8	Kong	Kong	NNP
cord-322166-ajolu2rh	209	9	were	be	VBD
cord-322166-ajolu2rh	209	10	the	the	DT
cord-322166-ajolu2rh	209	11	first	first	JJ
cord-322166-ajolu2rh	209	12	time	time	NN
cord-322166-ajolu2rh	209	13	that	that	WDT
cord-322166-ajolu2rh	209	14	the	the	DT
cord-322166-ajolu2rh	209	15	RT	RT	NNP
cord-322166-ajolu2rh	209	16	-	-	HYPH
cord-322166-ajolu2rh	209	17	PCR	PCR	NNP
cord-322166-ajolu2rh	209	18	method	method	NN
cord-322166-ajolu2rh	209	19	was	be	VBD
cord-322166-ajolu2rh	209	20	used	use	VBN
cord-322166-ajolu2rh	209	21	for	for	IN
cord-322166-ajolu2rh	209	22	specific	specific	JJ
cord-322166-ajolu2rh	209	23	detection	detection	NN
cord-322166-ajolu2rh	209	24	of	of	IN
cord-322166-ajolu2rh	209	25	the	the	DT
cord-322166-ajolu2rh	209	26	H5	H5	NNP
cord-322166-ajolu2rh	209	27	gene	gene	NN
cord-322166-ajolu2rh	209	28	segment	segment	NN
cord-322166-ajolu2rh	209	29	.	.	.
cord-322166-ajolu2rh	210	1	It	-PRON-	PRP
cord-322166-ajolu2rh	210	2	proved	prove	VBD
cord-322166-ajolu2rh	210	3	to	to	TO
cord-322166-ajolu2rh	210	4	be	be	VB
cord-322166-ajolu2rh	210	5	a	a	DT
cord-322166-ajolu2rh	210	6	valuable	valuable	JJ
cord-322166-ajolu2rh	210	7	diagnostic	diagnostic	JJ
cord-322166-ajolu2rh	210	8	tool	tool	NN
cord-322166-ajolu2rh	210	9	when	when	WRB
cord-322166-ajolu2rh	210	10	used	use	VBN
cord-322166-ajolu2rh	210	11	in	in	IN
cord-322166-ajolu2rh	210	12	association	association	NN
cord-322166-ajolu2rh	210	13	with	with	IN
cord-322166-ajolu2rh	210	14	identification	identification	NN
cord-322166-ajolu2rh	210	15	of	of	IN
cord-322166-ajolu2rh	210	16	clinical	clinical	JJ
cord-322166-ajolu2rh	210	17	features	feature	NNS
cord-322166-ajolu2rh	211	1	(	(	-LRB-
cord-322166-ajolu2rh	211	2	Yuen	Yuen	NNP
cord-322166-ajolu2rh	211	3	K	K	NNP
cord-322166-ajolu2rh	211	4	Y	Y	NNP
cord-322166-ajolu2rh	211	5	,	,	,
cord-322166-ajolu2rh	211	6	et	et	NNP
cord-322166-ajolu2rh	211	7	al	al	NNP
cord-322166-ajolu2rh	211	8	.	.	NNP
cord-322166-ajolu2rh	211	9	,	,	,
cord-322166-ajolu2rh	211	10	1998	1998	CD
cord-322166-ajolu2rh	211	11	)	)	-RRB-
cord-322166-ajolu2rh	211	12	.	.	.
cord-322166-ajolu2rh	212	1	The	the	DT
cord-322166-ajolu2rh	212	2	more	more	RBR
cord-322166-ajolu2rh	212	3	recently	recently	RB
cord-322166-ajolu2rh	212	4	developed	develop	VBN
cord-322166-ajolu2rh	212	5	real	real	JJ
cord-322166-ajolu2rh	212	6	-	-	HYPH
cord-322166-ajolu2rh	212	7	time	time	NN
cord-322166-ajolu2rh	212	8	RT	RT	NNP
cord-322166-ajolu2rh	212	9	-	-	HYPH
cord-322166-ajolu2rh	212	10	PCR	PCR	NNP
cord-322166-ajolu2rh	212	11	(	(	-LRB-
cord-322166-ajolu2rh	212	12	RRT	RRT	NNP
cord-322166-ajolu2rh	212	13	-	-	HYPH
cord-322166-ajolu2rh	212	14	PCR	PCR	NNP
cord-322166-ajolu2rh	212	15	)	)	-RRB-
cord-322166-ajolu2rh	212	16	is	be	VBZ
cord-322166-ajolu2rh	212	17	more	more	RBR
cord-322166-ajolu2rh	212	18	efficient	efficient	JJ
cord-322166-ajolu2rh	212	19	and	and	CC
cord-322166-ajolu2rh	212	20	accurate	accurate	JJ
cord-322166-ajolu2rh	212	21	than	than	IN
cord-322166-ajolu2rh	212	22	the	the	DT
cord-322166-ajolu2rh	212	23	standard	standard	JJ
cord-322166-ajolu2rh	212	24	RT	RT	NNP
cord-322166-ajolu2rh	212	25	-	-	HYPH
cord-322166-ajolu2rh	212	26	PCR	PCR	NNP
cord-322166-ajolu2rh	212	27	method	method	NN
cord-322166-ajolu2rh	212	28	(	(	-LRB-
cord-322166-ajolu2rh	212	29	Das	Das	NNP
cord-322166-ajolu2rh	212	30	A	A	NNP
cord-322166-ajolu2rh	212	31	,	,	,
cord-322166-ajolu2rh	212	32	et	et	NNP
cord-322166-ajolu2rh	212	33	al	al	NNP
cord-322166-ajolu2rh	212	34	.	.	NNP
cord-322166-ajolu2rh	212	35	,	,	,
cord-322166-ajolu2rh	212	36	2006	2006	CD
cord-322166-ajolu2rh	212	37	)	)	-RRB-
cord-322166-ajolu2rh	212	38	.	.	.
cord-322166-ajolu2rh	213	1	Other	other	JJ
cord-322166-ajolu2rh	213	2	assays	assay	NNS
cord-322166-ajolu2rh	213	3	such	such	JJ
cord-322166-ajolu2rh	213	4	as	as	IN
cord-322166-ajolu2rh	213	5	nucleic	nucleic	JJ
cord-322166-ajolu2rh	213	6	acid	acid	NN
cord-322166-ajolu2rh	213	7	sequence	sequence	NN
cord-322166-ajolu2rh	213	8	-	-	HYPH
cord-322166-ajolu2rh	213	9	based	base	VBN
cord-322166-ajolu2rh	213	10	amplification	amplification	NN
cord-322166-ajolu2rh	213	11	,	,	,
cord-322166-ajolu2rh	213	12	TaqMan	TaqMan	NNP
cord-322166-ajolu2rh	213	13	,	,	,
cord-322166-ajolu2rh	213	14	and	and	CC
cord-322166-ajolu2rh	213	15	fluorescence	fluorescence	NN
cord-322166-ajolu2rh	213	16	resonance	resonance	NN
cord-322166-ajolu2rh	213	17	energy	energy	NN
cord-322166-ajolu2rh	213	18	transfer	transfer	NN
cord-322166-ajolu2rh	213	19	have	have	VBP
cord-322166-ajolu2rh	213	20	also	also	RB
cord-322166-ajolu2rh	213	21	been	be	VBN
cord-322166-ajolu2rh	213	22	studied	study	VBN
cord-322166-ajolu2rh	213	23	.	.	.
cord-322166-ajolu2rh	214	1	These	these	DT
cord-322166-ajolu2rh	214	2	molecular	molecular	JJ
cord-322166-ajolu2rh	214	3	assays	assay	NNS
cord-322166-ajolu2rh	214	4	are	be	VBP
cord-322166-ajolu2rh	214	5	highly	highly	RB
cord-322166-ajolu2rh	214	6	specific	specific	JJ
cord-322166-ajolu2rh	214	7	for	for	IN
cord-322166-ajolu2rh	214	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	214	9	,	,	,
cord-322166-ajolu2rh	214	10	and	and	CC
cord-322166-ajolu2rh	214	11	can	can	MD
cord-322166-ajolu2rh	214	12	be	be	VB
cord-322166-ajolu2rh	214	13	used	use	VBN
cord-322166-ajolu2rh	214	14	to	to	TO
cord-322166-ajolu2rh	214	15	detect	detect	VB
cord-322166-ajolu2rh	214	16	H5N1	H5N1	NNP
cord-322166-ajolu2rh	214	17	from	from	IN
cord-322166-ajolu2rh	214	18	a	a	DT
cord-322166-ajolu2rh	214	19	wide	wide	JJ
cord-322166-ajolu2rh	214	20	range	range	NN
cord-322166-ajolu2rh	214	21	of	of	IN
cord-322166-ajolu2rh	214	22	hosts	host	NNS
cord-322166-ajolu2rh	215	1	(	(	-LRB-
cord-322166-ajolu2rh	215	2	Chantratita	Chantratita	NNP
cord-322166-ajolu2rh	215	3	W	W	NNP
cord-322166-ajolu2rh	215	4	,	,	,
cord-322166-ajolu2rh	215	5	et	et	NNP
cord-322166-ajolu2rh	215	6	al	al	NNP
cord-322166-ajolu2rh	215	7	.	.	NNP
cord-322166-ajolu2rh	215	8	,	,	,
cord-322166-ajolu2rh	215	9	2008	2008	CD
cord-322166-ajolu2rh	215	10	)	)	-RRB-
cord-322166-ajolu2rh	215	11	.	.	.
cord-322166-ajolu2rh	216	1	The	the	DT
cord-322166-ajolu2rh	216	2	disadvantage	disadvantage	NN
cord-322166-ajolu2rh	216	3	of	of	IN
cord-322166-ajolu2rh	216	4	all	all	DT
cord-322166-ajolu2rh	216	5	nucleic	nucleic	JJ
cord-322166-ajolu2rh	216	6	acid	acid	NN
cord-322166-ajolu2rh	216	7	-	-	HYPH
cord-322166-ajolu2rh	216	8	based	base	VBN
cord-322166-ajolu2rh	216	9	methods	method	NNS
cord-322166-ajolu2rh	216	10	is	be	VBZ
cord-322166-ajolu2rh	216	11	the	the	DT
cord-322166-ajolu2rh	216	12	need	need	NN
cord-322166-ajolu2rh	216	13	for	for	IN
cord-322166-ajolu2rh	216	14	sequence	sequence	NN
cord-322166-ajolu2rh	216	15	information	information	NN
cord-322166-ajolu2rh	216	16	for	for	IN
cord-322166-ajolu2rh	216	17	specific	specific	JJ
cord-322166-ajolu2rh	216	18	genes	gene	NNS
cord-322166-ajolu2rh	216	19	such	such	JJ
cord-322166-ajolu2rh	216	20	as	as	IN
cord-322166-ajolu2rh	216	21	HA	HA	NNP
cord-322166-ajolu2rh	216	22	and	and	CC
cord-322166-ajolu2rh	216	23	NA	NA	NNP
cord-322166-ajolu2rh	216	24	,	,	,
cord-322166-ajolu2rh	216	25	as	as	RB
cord-322166-ajolu2rh	216	26	well	well	RB
cord-322166-ajolu2rh	216	27	as	as	IN
cord-322166-ajolu2rh	216	28	NP	NP	NNP
cord-322166-ajolu2rh	216	29	.	.	.
cord-322166-ajolu2rh	217	1	The	the	DT
cord-322166-ajolu2rh	217	2	existence	existence	NN
cord-322166-ajolu2rh	217	3	of	of	IN
cord-322166-ajolu2rh	217	4	several	several	JJ
cord-322166-ajolu2rh	217	5	distinct	distinct	JJ
cord-322166-ajolu2rh	217	6	sub	sub	NN
cord-322166-ajolu2rh	217	7	-	-	HYPH
cord-322166-ajolu2rh	217	8	lineages	lineage	NNS
cord-322166-ajolu2rh	217	9	and	and	CC
cord-322166-ajolu2rh	217	10	the	the	DT
cord-322166-ajolu2rh	217	11	high	high	JJ
cord-322166-ajolu2rh	217	12	mutability	mutability	NN
cord-322166-ajolu2rh	217	13	of	of	IN
cord-322166-ajolu2rh	217	14	H5N1	H5N1	NNP
cord-322166-ajolu2rh	217	15	viruses	virus	NNS
cord-322166-ajolu2rh	217	16	may	may	MD
cord-322166-ajolu2rh	217	17	then	then	RB
cord-322166-ajolu2rh	217	18	lead	lead	VB
cord-322166-ajolu2rh	217	19	to	to	IN
cord-322166-ajolu2rh	217	20	increasing	increase	VBG
cord-322166-ajolu2rh	217	21	difficulties	difficulty	NNS
cord-322166-ajolu2rh	217	22	in	in	IN
cord-322166-ajolu2rh	217	23	identifying	identify	VBG
cord-322166-ajolu2rh	217	24	the	the	DT
cord-322166-ajolu2rh	217	25	virus	virus	NN
cord-322166-ajolu2rh	217	26	in	in	IN
cord-322166-ajolu2rh	217	27	patient	patient	NN
cord-322166-ajolu2rh	217	28	isolates	isolate	NNS
cord-322166-ajolu2rh	217	29	(	(	-LRB-
cord-322166-ajolu2rh	217	30	Cattoli	Cattoli	NNP
cord-322166-ajolu2rh	217	31	G	G	NNP
cord-322166-ajolu2rh	217	32	,	,	,
cord-322166-ajolu2rh	217	33	et	et	NNP
cord-322166-ajolu2rh	217	34	al	al	NNP
cord-322166-ajolu2rh	217	35	.	.	NNP
cord-322166-ajolu2rh	217	36	,	,	,
cord-322166-ajolu2rh	217	37	2009	2009	CD
cord-322166-ajolu2rh	217	38	;	;	:
cord-322166-ajolu2rh	217	39	Loeffelholz	Loeffelholz	NNP
cord-322166-ajolu2rh	217	40	M	M	NNP
cord-322166-ajolu2rh	217	41	J	J	NNP
cord-322166-ajolu2rh	217	42	,	,	,
cord-322166-ajolu2rh	217	43	2010	2010	CD
cord-322166-ajolu2rh	217	44	)	)	-RRB-
cord-322166-ajolu2rh	217	45	.	.	.
cord-322166-ajolu2rh	218	1	Hemagglutination	hemagglutination	NN
cord-322166-ajolu2rh	218	2	inhibition	inhibition	NN
cord-322166-ajolu2rh	218	3	and	and	CC
cord-322166-ajolu2rh	218	4	micro	micro	NN
cord-322166-ajolu2rh	218	5	-	-	NN
cord-322166-ajolu2rh	218	6	neutralization	neutralization	NN
cord-322166-ajolu2rh	218	7	are	be	VBP
cord-322166-ajolu2rh	218	8	sensitive	sensitive	JJ
cord-322166-ajolu2rh	218	9	serological	serological	JJ
cord-322166-ajolu2rh	218	10	assays	assay	NNS
cord-322166-ajolu2rh	218	11	for	for	IN
cord-322166-ajolu2rh	218	12	virus	virus	NN
cord-322166-ajolu2rh	218	13	detection	detection	NN
cord-322166-ajolu2rh	218	14	,	,	,
cord-322166-ajolu2rh	218	15	and	and	CC
cord-322166-ajolu2rh	218	16	are	be	VBP
cord-322166-ajolu2rh	218	17	considered	consider	VBN
cord-322166-ajolu2rh	218	18	the	the	DT
cord-322166-ajolu2rh	218	19	gold	gold	NN
cord-322166-ajolu2rh	218	20	standards	standard	NNS
cord-322166-ajolu2rh	218	21	for	for	IN
cord-322166-ajolu2rh	218	22	detection	detection	NN
cord-322166-ajolu2rh	218	23	of	of	IN
cord-322166-ajolu2rh	218	24	anti	anti	JJ
cord-322166-ajolu2rh	218	25	-	-	JJ
cord-322166-ajolu2rh	218	26	H5-specific	h5-specific	JJ
cord-322166-ajolu2rh	218	27	antibodies	antibody	NNS
cord-322166-ajolu2rh	218	28	in	in	IN
cord-322166-ajolu2rh	218	29	humans	human	NNS
cord-322166-ajolu2rh	219	1	(	(	-LRB-
cord-322166-ajolu2rh	219	2	Noah	Noah	NNP
cord-322166-ajolu2rh	219	3	D	D	NNP
cord-322166-ajolu2rh	219	4	L	L	NNP
cord-322166-ajolu2rh	219	5	,	,	,
cord-322166-ajolu2rh	219	6	et	et	NNP
cord-322166-ajolu2rh	219	7	al	al	NNP
cord-322166-ajolu2rh	219	8	.	.	NNP
cord-322166-ajolu2rh	219	9	,	,	,
cord-322166-ajolu2rh	219	10	2009	2009	CD
cord-322166-ajolu2rh	219	11	;	;	:
cord-322166-ajolu2rh	219	12	Ohnishi	Ohnishi	NNP
cord-322166-ajolu2rh	219	13	K	K	NNP
cord-322166-ajolu2rh	219	14	,	,	,
cord-322166-ajolu2rh	219	15	et	et	NNP
cord-322166-ajolu2rh	219	16	al	al	NNP
cord-322166-ajolu2rh	219	17	.	.	NNP
cord-322166-ajolu2rh	219	18	,	,	,
cord-322166-ajolu2rh	219	19	2012	2012	CD
cord-322166-ajolu2rh	219	20	;	;	:
cord-322166-ajolu2rh	219	21	Stelzer	Stelzer	NNP
cord-322166-ajolu2rh	219	22	-	-	HYPH
cord-322166-ajolu2rh	219	23	Braid	Braid	NNP
cord-322166-ajolu2rh	219	24	S	S	NNP
cord-322166-ajolu2rh	219	25	,	,	,
cord-322166-ajolu2rh	219	26	et	et	NNP
cord-322166-ajolu2rh	219	27	al	al	NNP
cord-322166-ajolu2rh	219	28	.	.	NNP
cord-322166-ajolu2rh	219	29	,	,	,
cord-322166-ajolu2rh	219	30	2008	2008	CD
cord-322166-ajolu2rh	219	31	)	)	-RRB-
cord-322166-ajolu2rh	219	32	.	.	.
cord-322166-ajolu2rh	220	1	These	these	DT
cord-322166-ajolu2rh	220	2	assays	assay	NNS
cord-322166-ajolu2rh	220	3	are	be	VBP
cord-322166-ajolu2rh	220	4	essential	essential	JJ
cord-322166-ajolu2rh	220	5	to	to	IN
cord-322166-ajolu2rh	220	6	providing	provide	VBG
cord-322166-ajolu2rh	220	7	a	a	DT
cord-322166-ajolu2rh	220	8	retrospective	retrospective	JJ
cord-322166-ajolu2rh	220	9	diagnosis	diagnosis	NN
cord-322166-ajolu2rh	220	10	to	to	TO
cord-322166-ajolu2rh	220	11	avoid	avoid	VB
cord-322166-ajolu2rh	220	12	potential	potential	JJ
cord-322166-ajolu2rh	220	13	false	false	JJ
cord-322166-ajolu2rh	220	14	-	-	HYPH
cord-322166-ajolu2rh	220	15	negatives	negative	NNS
cord-322166-ajolu2rh	220	16	and	and	CC
cord-322166-ajolu2rh	220	17	are	be	VBP
cord-322166-ajolu2rh	220	18	essential	essential	JJ
cord-322166-ajolu2rh	220	19	for	for	IN
cord-322166-ajolu2rh	220	20	epidemiological	epidemiological	JJ
cord-322166-ajolu2rh	220	21	investigations	investigation	NNS
cord-322166-ajolu2rh	220	22	.	.	.
cord-322166-ajolu2rh	221	1	The	the	DT
cord-322166-ajolu2rh	221	2	major	major	JJ
cord-322166-ajolu2rh	221	3	disadvantage	disadvantage	NN
cord-322166-ajolu2rh	221	4	of	of	IN
cord-322166-ajolu2rh	221	5	these	these	DT
cord-322166-ajolu2rh	221	6	methods	method	NNS
cord-322166-ajolu2rh	221	7	is	be	VBZ
cord-322166-ajolu2rh	221	8	that	that	IN
cord-322166-ajolu2rh	221	9	paired	pair	VBN
cord-322166-ajolu2rh	221	10	specimens	specimen	NNS
cord-322166-ajolu2rh	221	11	and	and	CC
cord-322166-ajolu2rh	221	12	H5-specific	h5-specific	JJ
cord-322166-ajolu2rh	221	13	reagents	reagent	NNS
cord-322166-ajolu2rh	221	14	for	for	IN
cord-322166-ajolu2rh	221	15	the	the	DT
cord-322166-ajolu2rh	221	16	subtypespecific	subtypespecific	NNP
cord-322166-ajolu2rh	221	17	antibodies	antibody	NNS
cord-322166-ajolu2rh	221	18	are	be	VBP
cord-322166-ajolu2rh	221	19	always	always	RB
cord-322166-ajolu2rh	221	20	not	not	RB
cord-322166-ajolu2rh	221	21	widely	widely	RB
cord-322166-ajolu2rh	221	22	available	available	JJ
cord-322166-ajolu2rh	221	23	and/or	and/or	CC
cord-322166-ajolu2rh	221	24	are	be	VBP
cord-322166-ajolu2rh	221	25	difficult	difficult	JJ
cord-322166-ajolu2rh	221	26	to	to	TO
cord-322166-ajolu2rh	221	27	detect	detect	VB
cord-322166-ajolu2rh	221	28	(	(	-LRB-
cord-322166-ajolu2rh	221	29	Ohnishi	Ohnishi	NNP
cord-322166-ajolu2rh	221	30	K	K	NNP
cord-322166-ajolu2rh	221	31	,	,	,
cord-322166-ajolu2rh	221	32	et	et	NNP
cord-322166-ajolu2rh	221	33	al	al	NNP
cord-322166-ajolu2rh	221	34	.	.	NNP
cord-322166-ajolu2rh	221	35	,	,	,
cord-322166-ajolu2rh	221	36	2012	2012	CD
cord-322166-ajolu2rh	221	37	)	)	-RRB-
cord-322166-ajolu2rh	221	38	.	.	.
cord-322166-ajolu2rh	222	1	As	as	IN
cord-322166-ajolu2rh	222	2	such	such	JJ
cord-322166-ajolu2rh	222	3	,	,	,
cord-322166-ajolu2rh	222	4	results	result	NNS
cord-322166-ajolu2rh	222	5	from	from	IN
cord-322166-ajolu2rh	222	6	these	these	DT
cord-322166-ajolu2rh	222	7	assays	assay	NNS
cord-322166-ajolu2rh	222	8	may	may	MD
cord-322166-ajolu2rh	222	9	only	only	RB
cord-322166-ajolu2rh	222	10	serve	serve	VB
cord-322166-ajolu2rh	222	11	as	as	IN
cord-322166-ajolu2rh	222	12	additional	additional	JJ
cord-322166-ajolu2rh	222	13	,	,	,
cord-322166-ajolu2rh	222	14	but	but	CC
cord-322166-ajolu2rh	222	15	not	not	RB
cord-322166-ajolu2rh	222	16	necessarily	necessarily	RB
cord-322166-ajolu2rh	222	17	preferential	preferential	JJ
cord-322166-ajolu2rh	222	18	,	,	,
cord-322166-ajolu2rh	222	19	methods	method	NNS
cord-322166-ajolu2rh	222	20	for	for	IN
cord-322166-ajolu2rh	222	21	laboratory	laboratory	NN
cord-322166-ajolu2rh	222	22	diagnosis	diagnosis	NN
cord-322166-ajolu2rh	222	23	.	.	.
cord-322166-ajolu2rh	223	1	Other	other	JJ
cord-322166-ajolu2rh	223	2	methods	method	NNS
cord-322166-ajolu2rh	223	3	such	such	JJ
cord-322166-ajolu2rh	223	4	as	as	IN
cord-322166-ajolu2rh	223	5	rapid	rapid	JJ
cord-322166-ajolu2rh	223	6	antigen	antigen	NN
cord-322166-ajolu2rh	223	7	detection	detection	NN
cord-322166-ajolu2rh	223	8	tests	test	NNS
cord-322166-ajolu2rh	223	9	(	(	-LRB-
cord-322166-ajolu2rh	223	10	e.g.	e.g.	RB
cord-322166-ajolu2rh	223	11	,	,	,
cord-322166-ajolu2rh	223	12	immunofluorescence	immunofluorescence	NN
cord-322166-ajolu2rh	223	13	)	)	-RRB-
cord-322166-ajolu2rh	223	14	are	be	VBP
cord-322166-ajolu2rh	223	15	simple	simple	JJ
cord-322166-ajolu2rh	223	16	and	and	CC
cord-322166-ajolu2rh	223	17	rapid	rapid	JJ
cord-322166-ajolu2rh	223	18	,	,	,
cord-322166-ajolu2rh	223	19	but	but	CC
cord-322166-ajolu2rh	223	20	suffer	suffer	VB
cord-322166-ajolu2rh	223	21	from	from	IN
cord-322166-ajolu2rh	223	22	a	a	DT
cord-322166-ajolu2rh	223	23	lack	lack	NN
cord-322166-ajolu2rh	223	24	of	of	IN
cord-322166-ajolu2rh	223	25	sensitivity	sensitivity	NN
cord-322166-ajolu2rh	223	26	(	(	-LRB-
cord-322166-ajolu2rh	223	27	Clementi	Clementi	NNP
cord-322166-ajolu2rh	223	28	N	N	NNP
cord-322166-ajolu2rh	223	29	,	,	,
cord-322166-ajolu2rh	223	30	et	et	NNP
cord-322166-ajolu2rh	223	31	al	al	NNP
cord-322166-ajolu2rh	223	32	.	.	NNP
cord-322166-ajolu2rh	223	33	,	,	,
cord-322166-ajolu2rh	223	34	2011	2011	CD
cord-322166-ajolu2rh	223	35	)	)	-RRB-
cord-322166-ajolu2rh	223	36	.	.	.
cord-322166-ajolu2rh	224	1	The	the	DT
cord-322166-ajolu2rh	224	2	rapid	rapid	JJ
cord-322166-ajolu2rh	224	3	antigen	antigen	NN
cord-322166-ajolu2rh	224	4	test	test	NN
cord-322166-ajolu2rh	224	5	usually	usually	RB
cord-322166-ajolu2rh	224	6	fails	fail	VBZ
cord-322166-ajolu2rh	224	7	to	to	TO
cord-322166-ajolu2rh	224	8	distinguish	distinguish	VB
cord-322166-ajolu2rh	224	9	between	between	IN
cord-322166-ajolu2rh	224	10	type	type	NN
cord-322166-ajolu2rh	224	11	A	a	NN
cord-322166-ajolu2rh	224	12	and	and	CC
cord-322166-ajolu2rh	224	13	type	type	NN
cord-322166-ajolu2rh	224	14	B	b	NN
cord-322166-ajolu2rh	224	15	viruses	virus	NNS
cord-322166-ajolu2rh	224	16	,	,	,
cord-322166-ajolu2rh	224	17	and	and	CC
cord-322166-ajolu2rh	224	18	can	can	MD
cord-322166-ajolu2rh	224	19	not	not	RB
cord-322166-ajolu2rh	224	20	distinguish	distinguish	VB
cord-322166-ajolu2rh	224	21	among	among	IN
cord-322166-ajolu2rh	224	22	AIV	AIV	NNP
cord-322166-ajolu2rh	224	23	subtypes	subtype	NNS
cord-322166-ajolu2rh	224	24	(	(	-LRB-
cord-322166-ajolu2rh	224	25	Clementi	Clementi	NNP
cord-322166-ajolu2rh	224	26	N	N	NNP
cord-322166-ajolu2rh	224	27	,	,	,
cord-322166-ajolu2rh	224	28	et	et	NNP
cord-322166-ajolu2rh	224	29	al	al	NNP
cord-322166-ajolu2rh	224	30	.	.	NNP
cord-322166-ajolu2rh	224	31	,	,	,
cord-322166-ajolu2rh	224	32	2011	2011	CD
cord-322166-ajolu2rh	224	33	)	)	-RRB-
cord-322166-ajolu2rh	224	34	.	.	.
cord-322166-ajolu2rh	225	1	Two	two	CD
cord-322166-ajolu2rh	225	2	classes	class	NNS
cord-322166-ajolu2rh	225	3	of	of	IN
cord-322166-ajolu2rh	225	4	antiviral	antiviral	JJ
cord-322166-ajolu2rh	225	5	drugs	drug	NNS
cord-322166-ajolu2rh	225	6	that	that	WDT
cord-322166-ajolu2rh	225	7	target	target	VBP
cord-322166-ajolu2rh	225	8	influenza	influenza	NN
cord-322166-ajolu2rh	225	9	virus	virus	NN
cord-322166-ajolu2rh	225	10	M2	M2	NNP
cord-322166-ajolu2rh	225	11	or	or	CC
cord-322166-ajolu2rh	225	12	NA	NA	NNP
cord-322166-ajolu2rh	225	13	are	be	VBP
cord-322166-ajolu2rh	225	14	commonly	commonly	RB
cord-322166-ajolu2rh	225	15	used	use	VBN
cord-322166-ajolu2rh	225	16	for	for	IN
cord-322166-ajolu2rh	225	17	prophylaxis	prophylaxis	NN
cord-322166-ajolu2rh	225	18	and	and	CC
cord-322166-ajolu2rh	225	19	treatment	treatment	NN
cord-322166-ajolu2rh	225	20	of	of	IN
cord-322166-ajolu2rh	225	21	influenza	influenza	NN
cord-322166-ajolu2rh	225	22	virus	virus	NN
cord-322166-ajolu2rh	225	23	infection	infection	NN
cord-322166-ajolu2rh	225	24	(	(	-LRB-
cord-322166-ajolu2rh	225	25	Sambhara	Sambhara	NNP
cord-322166-ajolu2rh	225	26	S	S	NNP
cord-322166-ajolu2rh	225	27	,	,	,
cord-322166-ajolu2rh	225	28	et	et	NNP
cord-322166-ajolu2rh	225	29	al	al	NNP
cord-322166-ajolu2rh	225	30	.	.	NNP
cord-322166-ajolu2rh	225	31	,	,	,
cord-322166-ajolu2rh	225	32	2010	2010	CD
cord-322166-ajolu2rh	225	33	)	)	-RRB-
cord-322166-ajolu2rh	225	34	.	.	.
cord-322166-ajolu2rh	226	1	Both	both	CC
cord-322166-ajolu2rh	226	2	amantadine	amantadine	NNP
cord-322166-ajolu2rh	226	3	and	and	CC
cord-322166-ajolu2rh	226	4	rimantadine	rimantadine	NNP
cord-322166-ajolu2rh	226	5	block	block	VBP
cord-322166-ajolu2rh	226	6	the	the	DT
cord-322166-ajolu2rh	226	7	ion	ion	NN
cord-322166-ajolu2rh	226	8	channel	channel	NN
cord-322166-ajolu2rh	226	9	formed	form	VBN
cord-322166-ajolu2rh	226	10	by	by	IN
cord-322166-ajolu2rh	226	11	the	the	DT
cord-322166-ajolu2rh	226	12	M2	M2	NNP
cord-322166-ajolu2rh	226	13	protein	protein	NN
cord-322166-ajolu2rh	226	14	,	,	,
cord-322166-ajolu2rh	226	15	thus	thus	RB
cord-322166-ajolu2rh	226	16	inhibiting	inhibit	VBG
cord-322166-ajolu2rh	226	17	viral	viral	JJ
cord-322166-ajolu2rh	226	18	entry	entry	NN
cord-322166-ajolu2rh	226	19	and	and	CC
cord-322166-ajolu2rh	226	20	replication	replication	NN
cord-322166-ajolu2rh	226	21	(	(	-LRB-
cord-322166-ajolu2rh	226	22	Couch	couch	NN
cord-322166-ajolu2rh	226	23	R	r	NN
cord-322166-ajolu2rh	226	24	B	b	NN
cord-322166-ajolu2rh	226	25	,	,	,
cord-322166-ajolu2rh	226	26	2000	2000	CD
cord-322166-ajolu2rh	226	27	;	;	:
cord-322166-ajolu2rh	226	28	Sambhara	Sambhara	NNP
cord-322166-ajolu2rh	226	29	S	S	NNP
cord-322166-ajolu2rh	226	30	,	,	,
cord-322166-ajolu2rh	226	31	et	et	NNP
cord-322166-ajolu2rh	226	32	al	al	NNP
cord-322166-ajolu2rh	226	33	.	.	NNP
cord-322166-ajolu2rh	226	34	,	,	,
cord-322166-ajolu2rh	226	35	2010	2010	CD
cord-322166-ajolu2rh	226	36	)	)	-RRB-
cord-322166-ajolu2rh	226	37	.	.	.
cord-322166-ajolu2rh	227	1	The	the	DT
cord-322166-ajolu2rh	227	2	second	second	JJ
cord-322166-ajolu2rh	227	3	class	class	NN
cord-322166-ajolu2rh	227	4	of	of	IN
cord-322166-ajolu2rh	227	5	antiviral	antiviral	JJ
cord-322166-ajolu2rh	227	6	drug	drug	NN
cord-322166-ajolu2rh	227	7	,	,	,
cord-322166-ajolu2rh	227	8	including	include	VBG
cord-322166-ajolu2rh	227	9	zanamivir	zanamivir	NNP
cord-322166-ajolu2rh	227	10	and	and	CC
cord-322166-ajolu2rh	227	11	oseltamivir	oseltamivir	NNP
cord-322166-ajolu2rh	227	12	,	,	,
cord-322166-ajolu2rh	227	13	acts	act	VBZ
cord-322166-ajolu2rh	227	14	on	on	IN
cord-322166-ajolu2rh	227	15	NA	NA	NNP
cord-322166-ajolu2rh	227	16	to	to	TO
cord-322166-ajolu2rh	227	17	prevent	prevent	VB
cord-322166-ajolu2rh	227	18	virus	virus	NN
cord-322166-ajolu2rh	227	19	release	release	NN
cord-322166-ajolu2rh	227	20	from	from	IN
cord-322166-ajolu2rh	227	21	infected	infected	JJ
cord-322166-ajolu2rh	227	22	cells	cell	NNS
cord-322166-ajolu2rh	227	23	(	(	-LRB-
cord-322166-ajolu2rh	227	24	de	de	FW
cord-322166-ajolu2rh	227	25	Jong	Jong	NNP
cord-322166-ajolu2rh	227	26	M	M	NNP
cord-322166-ajolu2rh	227	27	D	D	NNP
cord-322166-ajolu2rh	227	28	,	,	,
cord-322166-ajolu2rh	227	29	et	et	NNP
cord-322166-ajolu2rh	227	30	al	al	NNP
cord-322166-ajolu2rh	227	31	.	.	NNP
cord-322166-ajolu2rh	227	32	,	,	,
cord-322166-ajolu2rh	227	33	2006	2006	CD
cord-322166-ajolu2rh	227	34	)	)	-RRB-
cord-322166-ajolu2rh	227	35	.	.	.
cord-322166-ajolu2rh	228	1	However	however	RB
cord-322166-ajolu2rh	228	2	,	,	,
cord-322166-ajolu2rh	228	3	there	there	EX
cord-322166-ajolu2rh	228	4	appear	appear	VBP
cord-322166-ajolu2rh	228	5	to	to	TO
cord-322166-ajolu2rh	228	6	be	be	VB
cord-322166-ajolu2rh	228	7	several	several	JJ
cord-322166-ajolu2rh	228	8	virus	virus	NN
cord-322166-ajolu2rh	228	9	clades	clade	NNS
cord-322166-ajolu2rh	228	10	that	that	WDT
cord-322166-ajolu2rh	228	11	are	be	VBP
cord-322166-ajolu2rh	228	12	resistant	resistant	JJ
cord-322166-ajolu2rh	228	13	to	to	IN
cord-322166-ajolu2rh	228	14	these	these	DT
cord-322166-ajolu2rh	228	15	drugs	drug	NNS
cord-322166-ajolu2rh	229	1	(	(	-LRB-
cord-322166-ajolu2rh	229	2	Le	Le	NNP
cord-322166-ajolu2rh	229	3	Q	Q	NNP
cord-322166-ajolu2rh	229	4	M	M	NNP
cord-322166-ajolu2rh	229	5	,	,	,
cord-322166-ajolu2rh	229	6	et	et	NNP
cord-322166-ajolu2rh	229	7	al	al	NNP
cord-322166-ajolu2rh	229	8	.	.	NNP
cord-322166-ajolu2rh	229	9	,	,	,
cord-322166-ajolu2rh	229	10	2005	2005	CD
cord-322166-ajolu2rh	229	11	)	)	-RRB-
cord-322166-ajolu2rh	229	12	.	.	.
cord-322166-ajolu2rh	230	1	The	the	DT
cord-322166-ajolu2rh	230	2	emergence	emergence	NN
cord-322166-ajolu2rh	230	3	of	of	IN
cord-322166-ajolu2rh	230	4	oseltamivir	oseltamivir	NN
cord-322166-ajolu2rh	230	5	-	-	,
cord-322166-ajolu2rh	230	6	or	or	CC
cord-322166-ajolu2rh	230	7	amantadine	amantadine	NN
cord-322166-ajolu2rh	230	8	-	-	HYPH
cord-322166-ajolu2rh	230	9	resistant	resistant	JJ
cord-322166-ajolu2rh	230	10	strains	strain	NNS
cord-322166-ajolu2rh	230	11	10	10	CD
cord-322166-ajolu2rh	230	12	restricts	restrict	VBZ
cord-322166-ajolu2rh	230	13	the	the	DT
cord-322166-ajolu2rh	230	14	ability	ability	NN
cord-322166-ajolu2rh	230	15	to	to	TO
cord-322166-ajolu2rh	230	16	prevent	prevent	VB
cord-322166-ajolu2rh	230	17	influenza	influenza	NN
cord-322166-ajolu2rh	230	18	infections	infection	NNS
cord-322166-ajolu2rh	230	19	and	and	CC
cord-322166-ajolu2rh	230	20	treat	treat	VB
cord-322166-ajolu2rh	230	21	patients	patient	NNS
cord-322166-ajolu2rh	230	22	effectively	effectively	RB
cord-322166-ajolu2rh	230	23	(	(	-LRB-
cord-322166-ajolu2rh	230	24	Cheung	Cheung	NNP
cord-322166-ajolu2rh	230	25	C	C	NNP
cord-322166-ajolu2rh	230	26	L	L	NNP
cord-322166-ajolu2rh	230	27	,	,	,
cord-322166-ajolu2rh	230	28	et	et	NNP
cord-322166-ajolu2rh	230	29	al	al	NNP
cord-322166-ajolu2rh	230	30	.	.	NNP
cord-322166-ajolu2rh	230	31	,	,	,
cord-322166-ajolu2rh	230	32	2006	2006	CD
cord-322166-ajolu2rh	230	33	;	;	:
cord-322166-ajolu2rh	230	34	de	de	NNP
cord-322166-ajolu2rh	230	35	Jong	Jong	NNP
cord-322166-ajolu2rh	230	36	M	M	NNP
cord-322166-ajolu2rh	230	37	D	D	NNP
cord-322166-ajolu2rh	230	38	,	,	,
cord-322166-ajolu2rh	230	39	et	et	NNP
cord-322166-ajolu2rh	230	40	al	al	NNP
cord-322166-ajolu2rh	230	41	.	.	NNP
cord-322166-ajolu2rh	230	42	,	,	,
cord-322166-ajolu2rh	230	43	2005	2005	CD
cord-322166-ajolu2rh	230	44	;	;	:
cord-322166-ajolu2rh	230	45	Le	Le	NNP
cord-322166-ajolu2rh	230	46	Q	Q	NNP
cord-322166-ajolu2rh	230	47	M	M	NNP
cord-322166-ajolu2rh	230	48	,	,	,
cord-322166-ajolu2rh	230	49	et	et	NNP
cord-322166-ajolu2rh	230	50	al	al	NNP
cord-322166-ajolu2rh	230	51	.	.	NNP
cord-322166-ajolu2rh	230	52	,	,	,
cord-322166-ajolu2rh	230	53	2005	2005	CD
cord-322166-ajolu2rh	230	54	;	;	:
cord-322166-ajolu2rh	230	55	Malaisree	Malaisree	NNP
cord-322166-ajolu2rh	230	56	M	M	NNP
cord-322166-ajolu2rh	230	57	,	,	,
cord-322166-ajolu2rh	230	58	et	et	NNP
cord-322166-ajolu2rh	230	59	al	al	NNP
cord-322166-ajolu2rh	230	60	.	.	NNP
cord-322166-ajolu2rh	230	61	,	,	,
cord-322166-ajolu2rh	230	62	2009	2009	CD
cord-322166-ajolu2rh	230	63	)	)	-RRB-
cord-322166-ajolu2rh	230	64	.	.	.
cord-322166-ajolu2rh	231	1	Following	follow	VBG
cord-322166-ajolu2rh	231	2	analysis	analysis	NN
cord-322166-ajolu2rh	231	3	of	of	IN
cord-322166-ajolu2rh	231	4	the	the	DT
cord-322166-ajolu2rh	231	5	three	three	CD
cord-322166-ajolu2rh	231	6	-	-	HYPH
cord-322166-ajolu2rh	231	7	dimensional	dimensional	JJ
cord-322166-ajolu2rh	231	8	structure	structure	NN
cord-322166-ajolu2rh	231	9	of	of	IN
cord-322166-ajolu2rh	231	10	NA	NA	NNP
cord-322166-ajolu2rh	231	11	from	from	IN
cord-322166-ajolu2rh	231	12	oseltamivir	oseltamivir	NN
cord-322166-ajolu2rh	231	13	-	-	HYPH
cord-322166-ajolu2rh	231	14	resistant	resistant	JJ
cord-322166-ajolu2rh	231	15	influenza	influenza	NN
cord-322166-ajolu2rh	231	16	strains	strain	NNS
cord-322166-ajolu2rh	231	17	,	,	,
cord-322166-ajolu2rh	231	18	six	six	CD
cord-322166-ajolu2rh	231	19	additional	additional	JJ
cord-322166-ajolu2rh	231	20	drug	drug	NN
cord-322166-ajolu2rh	231	21	analogs	analog	NNS
cord-322166-ajolu2rh	231	22	have	have	VBP
cord-322166-ajolu2rh	231	23	been	be	VBN
cord-322166-ajolu2rh	231	24	proposed	propose	VBN
cord-322166-ajolu2rh	231	25	to	to	TO
cord-322166-ajolu2rh	231	26	fight	fight	VB
cord-322166-ajolu2rh	231	27	H5N1	H5N1	NNP
cord-322166-ajolu2rh	231	28	(	(	-LRB-
cord-322166-ajolu2rh	231	29	Du	Du	NNP
cord-322166-ajolu2rh	231	30	Q	Q	NNP
cord-322166-ajolu2rh	231	31	S	S	NNP
cord-322166-ajolu2rh	231	32	,	,	,
cord-322166-ajolu2rh	231	33	et	et	NNP
cord-322166-ajolu2rh	231	34	al	al	NNP
cord-322166-ajolu2rh	231	35	.	.	NNP
cord-322166-ajolu2rh	231	36	,	,	,
cord-322166-ajolu2rh	231	37	2007	2007	CD
cord-322166-ajolu2rh	231	38	)	)	-RRB-
cord-322166-ajolu2rh	231	39	.	.	.
cord-322166-ajolu2rh	232	1	Including	include	VBG
cord-322166-ajolu2rh	232	2	inhibitors	inhibitor	NNS
cord-322166-ajolu2rh	232	3	of	of	IN
cord-322166-ajolu2rh	232	4	inflammation	inflammation	NN
cord-322166-ajolu2rh	232	5	,	,	,
cord-322166-ajolu2rh	232	6	such	such	JJ
cord-322166-ajolu2rh	232	7	as	as	IN
cord-322166-ajolu2rh	232	8	the	the	DT
cord-322166-ajolu2rh	232	9	combination	combination	NN
cord-322166-ajolu2rh	232	10	of	of	IN
cord-322166-ajolu2rh	232	11	celecoxib	celecoxib	NNS
cord-322166-ajolu2rh	232	12	or	or	CC
cord-322166-ajolu2rh	232	13	mesalazine	mesalazine	NN
cord-322166-ajolu2rh	232	14	to	to	IN
cord-322166-ajolu2rh	232	15	zanamivir	zanamivir	NNP
cord-322166-ajolu2rh	232	16	treatment	treatment	NN
cord-322166-ajolu2rh	232	17	has	have	VBZ
cord-322166-ajolu2rh	232	18	been	be	VBN
cord-322166-ajolu2rh	232	19	shown	show	VBN
cord-322166-ajolu2rh	232	20	to	to	TO
cord-322166-ajolu2rh	232	21	greatly	greatly	RB
cord-322166-ajolu2rh	232	22	reduce	reduce	VB
cord-322166-ajolu2rh	232	23	cell	cell	NN
cord-322166-ajolu2rh	232	24	death	death	NN
cord-322166-ajolu2rh	232	25	and	and	CC
cord-322166-ajolu2rh	232	26	host	host	NN
cord-322166-ajolu2rh	232	27	tissue	tissue	NN
cord-322166-ajolu2rh	232	28	damage	damage	NN
cord-322166-ajolu2rh	232	29	with	with	IN
cord-322166-ajolu2rh	232	30	a	a	DT
cord-322166-ajolu2rh	232	31	similar	similar	JJ
cord-322166-ajolu2rh	232	32	viral	viral	JJ
cord-322166-ajolu2rh	232	33	load	load	NN
cord-322166-ajolu2rh	232	34	compared	compare	VBN
cord-322166-ajolu2rh	232	35	to	to	IN
cord-322166-ajolu2rh	232	36	zanamivir	zanamivir	NNP
cord-322166-ajolu2rh	232	37	alone	alone	RB
cord-322166-ajolu2rh	233	1	(	(	-LRB-
cord-322166-ajolu2rh	233	2	Zheng	Zheng	NNP
cord-322166-ajolu2rh	233	3	B	B	NNP
cord-322166-ajolu2rh	233	4	J	J	NNP
cord-322166-ajolu2rh	233	5	,	,	,
cord-322166-ajolu2rh	233	6	et	et	NNP
cord-322166-ajolu2rh	233	7	al	al	NNP
cord-322166-ajolu2rh	233	8	.	.	NNP
cord-322166-ajolu2rh	233	9	,	,	,
cord-322166-ajolu2rh	233	10	2008	2008	CD
cord-322166-ajolu2rh	233	11	)	)	-RRB-
cord-322166-ajolu2rh	233	12	.	.	.
cord-322166-ajolu2rh	234	1	In	in	IN
cord-322166-ajolu2rh	234	2	addition	addition	NN
cord-322166-ajolu2rh	234	3	to	to	IN
cord-322166-ajolu2rh	234	4	antiviral	antiviral	JJ
cord-322166-ajolu2rh	234	5	drugs	drug	NNS
cord-322166-ajolu2rh	234	6	that	that	WDT
cord-322166-ajolu2rh	234	7	target	target	VBP
cord-322166-ajolu2rh	234	8	influenza	influenza	NN
cord-322166-ajolu2rh	234	9	virus	virus	NN
cord-322166-ajolu2rh	234	10	M2	M2	NNP
cord-322166-ajolu2rh	234	11	or	or	CC
cord-322166-ajolu2rh	234	12	NA	NA	NNP
cord-322166-ajolu2rh	234	13	,	,	,
cord-322166-ajolu2rh	234	14	various	various	JJ
cord-322166-ajolu2rh	234	15	molecules	molecule	NNS
cord-322166-ajolu2rh	234	16	with	with	IN
cord-322166-ajolu2rh	234	17	pharmacological	pharmacological	JJ
cord-322166-ajolu2rh	234	18	activity	activity	NN
cord-322166-ajolu2rh	234	19	,	,	,
cord-322166-ajolu2rh	234	20	such	such	JJ
cord-322166-ajolu2rh	234	21	as	as	IN
cord-322166-ajolu2rh	234	22	isopentenyl	isopentenyl	NNP
cord-322166-ajolu2rh	234	23	pyrophosphate	pyrophosphate	NNP
cord-322166-ajolu2rh	234	24	and	and	CC
cord-322166-ajolu2rh	234	25	aminobisphosphonates	aminobisphosphonates	NNP
cord-322166-ajolu2rh	234	26	like	like	IN
cord-322166-ajolu2rh	234	27	pamidronate	pamidronate	NNP
cord-322166-ajolu2rh	234	28	(	(	-LRB-
cord-322166-ajolu2rh	234	29	PAM	PAM	NNP
cord-322166-ajolu2rh	234	30	)	)	-RRB-
cord-322166-ajolu2rh	234	31	,	,	,
cord-322166-ajolu2rh	234	32	were	be	VBD
cord-322166-ajolu2rh	234	33	able	able	JJ
cord-322166-ajolu2rh	234	34	to	to	TO
cord-322166-ajolu2rh	234	35	activate	activate	VB
cord-322166-ajolu2rh	234	36	and	and	CC
cord-322166-ajolu2rh	234	37	expand	expand	VB
cord-322166-ajolu2rh	234	38	human	human	NN
cord-322166-ajolu2rh	234	39	γδ	γδ	IN
cord-322166-ajolu2rh	234	40	T	t	NN
cord-322166-ajolu2rh	234	41	cells	cell	NNS
cord-322166-ajolu2rh	234	42	(	(	-LRB-
cord-322166-ajolu2rh	234	43	Qin	Qin	NNP
cord-322166-ajolu2rh	234	44	G	G	NNP
cord-322166-ajolu2rh	234	45	,	,	,
cord-322166-ajolu2rh	234	46	et	et	NNP
cord-322166-ajolu2rh	234	47	al	al	NNP
cord-322166-ajolu2rh	234	48	.	.	NNP
cord-322166-ajolu2rh	234	49	,	,	,
cord-322166-ajolu2rh	234	50	2009	2009	CD
cord-322166-ajolu2rh	234	51	;	;	:
cord-322166-ajolu2rh	234	52	Tu	Tu	NNP
cord-322166-ajolu2rh	234	53	W	W	NNP
cord-322166-ajolu2rh	234	54	,	,	,
cord-322166-ajolu2rh	234	55	et	et	NNP
cord-322166-ajolu2rh	234	56	al	al	NNP
cord-322166-ajolu2rh	234	57	.	.	NNP
cord-322166-ajolu2rh	234	58	,	,	,
cord-322166-ajolu2rh	234	59	2011	2011	CD
cord-322166-ajolu2rh	234	60	)	)	-RRB-
cord-322166-ajolu2rh	234	61	,	,	,
cord-322166-ajolu2rh	234	62	suggesting	suggest	VBG
cord-322166-ajolu2rh	234	63	activation	activation	NN
cord-322166-ajolu2rh	234	64	of	of	IN
cord-322166-ajolu2rh	234	65	γδ	γδ	NNP
cord-322166-ajolu2rh	234	66	T	t	NN
cord-322166-ajolu2rh	234	67	-	-	HYPH
cord-322166-ajolu2rh	234	68	cell	cell	NN
cord-322166-ajolu2rh	234	69	-	-	HYPH
cord-322166-ajolu2rh	234	70	based	base	VBN
cord-322166-ajolu2rh	234	71	immunotherapy	immunotherapy	NN
cord-322166-ajolu2rh	234	72	as	as	IN
cord-322166-ajolu2rh	234	73	an	an	DT
cord-322166-ajolu2rh	234	74	alternative	alternative	JJ
cord-322166-ajolu2rh	234	75	strategy	strategy	NN
cord-322166-ajolu2rh	234	76	for	for	IN
cord-322166-ajolu2rh	234	77	treating	treat	VBG
cord-322166-ajolu2rh	234	78	influenza	influenza	NN
cord-322166-ajolu2rh	234	79	A	a	DT
cord-322166-ajolu2rh	234	80	infection	infection	NN
cord-322166-ajolu2rh	234	81	.	.	.
cord-322166-ajolu2rh	235	1	Recent	recent	JJ
cord-322166-ajolu2rh	235	2	studies	study	NNS
cord-322166-ajolu2rh	235	3	have	have	VBP
cord-322166-ajolu2rh	235	4	also	also	RB
cord-322166-ajolu2rh	235	5	identified	identify	VBN
cord-322166-ajolu2rh	235	6	several	several	JJ
cord-322166-ajolu2rh	235	7	additional	additional	JJ
cord-322166-ajolu2rh	235	8	candidate	candidate	NN
cord-322166-ajolu2rh	235	9	therapeutic	therapeutic	JJ
cord-322166-ajolu2rh	235	10	agents	agent	NNS
cord-322166-ajolu2rh	235	11	,	,	,
cord-322166-ajolu2rh	235	12	such	such	JJ
cord-322166-ajolu2rh	235	13	as	as	IN
cord-322166-ajolu2rh	235	14	a	a	DT
cord-322166-ajolu2rh	235	15	RIG	rig	NN
cord-322166-ajolu2rh	235	16	-	-	:
cord-322166-ajolu2rh	235	17	I	-PRON-	PRP
cord-322166-ajolu2rh	235	18	pathway	pathway	NN
cord-322166-ajolu2rh	235	19	activator	activator	NN
cord-322166-ajolu2rh	235	20	and	and	CC
cord-322166-ajolu2rh	235	21	IFNs	ifn	NNS
cord-322166-ajolu2rh	235	22	,	,	,
cord-322166-ajolu2rh	235	23	that	that	WDT
cord-322166-ajolu2rh	235	24	inhibit	inhibit	VBP
cord-322166-ajolu2rh	235	25	influenza	influenza	NN
cord-322166-ajolu2rh	235	26	viral	viral	JJ
cord-322166-ajolu2rh	235	27	replication	replication	NN
cord-322166-ajolu2rh	235	28	,	,	,
cord-322166-ajolu2rh	235	29	DAS181	DAS181	NNP
cord-322166-ajolu2rh	235	30	and	and	CC
cord-322166-ajolu2rh	235	31	its	-PRON-	PRP$
cord-322166-ajolu2rh	235	32	analogs	analog	NNS
cord-322166-ajolu2rh	235	33	that	that	IN
cord-322166-ajolu2rh	235	34	down	down	RB
cord-322166-ajolu2rh	235	35	-	-	HYPH
cord-322166-ajolu2rh	235	36	regulate	regulate	VB
cord-322166-ajolu2rh	235	37	receptor	receptor	NN
cord-322166-ajolu2rh	235	38	expression	expression	NN
cord-322166-ajolu2rh	235	39	on	on	IN
cord-322166-ajolu2rh	235	40	the	the	DT
cord-322166-ajolu2rh	235	41	surface	surface	NN
cord-322166-ajolu2rh	235	42	of	of	IN
cord-322166-ajolu2rh	235	43	the	the	DT
cord-322166-ajolu2rh	235	44	host	host	NN
cord-322166-ajolu2rh	235	45	cell	cell	NN
cord-322166-ajolu2rh	235	46	,	,	,
cord-322166-ajolu2rh	235	47	and	and	CC
cord-322166-ajolu2rh	235	48	antiviral	antiviral	JJ
cord-322166-ajolu2rh	235	49	siRNAs	siRNAs	NNP
cord-322166-ajolu2rh	235	50	that	that	WDT
cord-322166-ajolu2rh	235	51	target	target	VBP
cord-322166-ajolu2rh	235	52	viral	viral	JJ
cord-322166-ajolu2rh	235	53	genes	gene	NNS
cord-322166-ajolu2rh	235	54	that	that	WDT
cord-322166-ajolu2rh	235	55	inhibit	inhibit	VBP
cord-322166-ajolu2rh	235	56	H5N1	H5N1	NNP
cord-322166-ajolu2rh	235	57	infection	infection	NN
cord-322166-ajolu2rh	235	58	in	in	IN
cord-322166-ajolu2rh	235	59	vitro	vitro	FW
cord-322166-ajolu2rh	235	60	and	and	CC
cord-322166-ajolu2rh	235	61	in	in	IN
cord-322166-ajolu2rh	235	62	animal	animal	NN
cord-322166-ajolu2rh	235	63	models	model	NNS
cord-322166-ajolu2rh	236	1	(	(	-LRB-
cord-322166-ajolu2rh	236	2	Chan	Chan	NNP
cord-322166-ajolu2rh	236	3	R	R	NNP
cord-322166-ajolu2rh	236	4	W	W	NNP
cord-322166-ajolu2rh	236	5	,	,	,
cord-322166-ajolu2rh	236	6	et	et	NNP
cord-322166-ajolu2rh	236	7	al	al	NNP
cord-322166-ajolu2rh	236	8	.	.	NNP
cord-322166-ajolu2rh	236	9	,	,	,
cord-322166-ajolu2rh	236	10	2009	2009	CD
cord-322166-ajolu2rh	236	11	;	;	:
cord-322166-ajolu2rh	236	12	Luke	Luke	NNP
cord-322166-ajolu2rh	236	13	J	J	NNP
cord-322166-ajolu2rh	236	14	M	M	NNP
cord-322166-ajolu2rh	236	15	,	,	,
cord-322166-ajolu2rh	236	16	et	et	NNP
cord-322166-ajolu2rh	236	17	al	al	NNP
cord-322166-ajolu2rh	236	18	.	.	NNP
cord-322166-ajolu2rh	236	19	,	,	,
cord-322166-ajolu2rh	236	20	2011	2011	CD
cord-322166-ajolu2rh	236	21	;	;	:
cord-322166-ajolu2rh	236	22	Sambhara	Sambhara	NNP
cord-322166-ajolu2rh	236	23	S	S	NNP
cord-322166-ajolu2rh	236	24	,	,	,
cord-322166-ajolu2rh	236	25	et	et	NNP
cord-322166-ajolu2rh	236	26	al	al	NNP
cord-322166-ajolu2rh	236	27	.	.	NNP
cord-322166-ajolu2rh	236	28	,	,	,
cord-322166-ajolu2rh	236	29	2010	2010	CD
cord-322166-ajolu2rh	236	30	;	;	:
cord-322166-ajolu2rh	236	31	Stewart	Stewart	NNP
cord-322166-ajolu2rh	236	32	C	C	NNP
cord-322166-ajolu2rh	236	33	R	R	NNP
cord-322166-ajolu2rh	236	34	,	,	,
cord-322166-ajolu2rh	236	35	et	et	NNP
cord-322166-ajolu2rh	236	36	al	al	NNP
cord-322166-ajolu2rh	236	37	.	.	NNP
cord-322166-ajolu2rh	236	38	,	,	,
cord-322166-ajolu2rh	236	39	2011	2011	CD
cord-322166-ajolu2rh	236	40	;	;	:
cord-322166-ajolu2rh	236	41	Szretter	Szretter	NNP
cord-322166-ajolu2rh	236	42	K	K	NNP
cord-322166-ajolu2rh	236	43	J	J	NNP
cord-322166-ajolu2rh	236	44	,	,	,
cord-322166-ajolu2rh	236	45	et	et	NNP
cord-322166-ajolu2rh	236	46	al	al	NNP
cord-322166-ajolu2rh	236	47	.	.	NNP
cord-322166-ajolu2rh	236	48	,	,	,
cord-322166-ajolu2rh	236	49	2009	2009	CD
cord-322166-ajolu2rh	236	50	)	)	-RRB-
cord-322166-ajolu2rh	236	51	.	.	.
cord-322166-ajolu2rh	237	1	Other	other	JJ
cord-322166-ajolu2rh	237	2	candidate	candidate	NN
cord-322166-ajolu2rh	237	3	drugs	drug	NNS
cord-322166-ajolu2rh	237	4	such	such	JJ
cord-322166-ajolu2rh	237	5	as	as	IN
cord-322166-ajolu2rh	237	6	saponin	saponin	NN
cord-322166-ajolu2rh	237	7	derivatives	derivative	NNS
cord-322166-ajolu2rh	237	8	or	or	CC
cord-322166-ajolu2rh	237	9	other	other	JJ
cord-322166-ajolu2rh	237	10	active	active	JJ
cord-322166-ajolu2rh	237	11	compounds	compound	NNS
cord-322166-ajolu2rh	237	12	that	that	WDT
cord-322166-ajolu2rh	237	13	have	have	VBP
cord-322166-ajolu2rh	237	14	a	a	DT
cord-322166-ajolu2rh	237	15	chacotriosyl	chacotriosyl	JJ
cord-322166-ajolu2rh	237	16	residue	residue	NN
cord-322166-ajolu2rh	237	17	and	and	CC
cord-322166-ajolu2rh	237	18	chlorogenin	chlorogenin	NN
cord-322166-ajolu2rh	237	19	moiety	moiety	NN
cord-322166-ajolu2rh	237	20	may	may	MD
cord-322166-ajolu2rh	237	21	also	also	RB
cord-322166-ajolu2rh	237	22	serve	serve	VB
cord-322166-ajolu2rh	237	23	as	as	IN
cord-322166-ajolu2rh	237	24	host	host	NN
cord-322166-ajolu2rh	237	25	cell	cell	NN
cord-322166-ajolu2rh	237	26	entry	entry	NN
cord-322166-ajolu2rh	237	27	inhibitors	inhibitor	NNS
cord-322166-ajolu2rh	237	28	for	for	IN
cord-322166-ajolu2rh	237	29	highly	highly	RB
cord-322166-ajolu2rh	237	30	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	237	31	H5N1	H5N1	NNP
cord-322166-ajolu2rh	237	32	influenza	influenza	NN
cord-322166-ajolu2rh	237	33	virus	virus	NN
cord-322166-ajolu2rh	237	34	(	(	-LRB-
cord-322166-ajolu2rh	237	35	Ding	Ding	NNP
cord-322166-ajolu2rh	237	36	N	N	NNP
cord-322166-ajolu2rh	237	37	,	,	,
cord-322166-ajolu2rh	237	38	et	et	NNP
cord-322166-ajolu2rh	237	39	al	al	NNP
cord-322166-ajolu2rh	237	40	.	.	NNP
cord-322166-ajolu2rh	237	41	,	,	,
cord-322166-ajolu2rh	237	42	2012	2012	CD
cord-322166-ajolu2rh	237	43	)	)	-RRB-
cord-322166-ajolu2rh	237	44	.	.	.
cord-322166-ajolu2rh	238	1	Development	development	NN
cord-322166-ajolu2rh	238	2	of	of	IN
cord-322166-ajolu2rh	238	3	an	an	DT
cord-322166-ajolu2rh	238	4	effective	effective	JJ
cord-322166-ajolu2rh	238	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	238	6	vaccine	vaccine	NN
cord-322166-ajolu2rh	238	7	poses	pose	VBZ
cord-322166-ajolu2rh	238	8	a	a	DT
cord-322166-ajolu2rh	238	9	number	number	NN
cord-322166-ajolu2rh	238	10	of	of	IN
cord-322166-ajolu2rh	238	11	substantial	substantial	JJ
cord-322166-ajolu2rh	238	12	challenges	challenge	NNS
cord-322166-ajolu2rh	238	13	.	.	.
cord-322166-ajolu2rh	239	1	Newly	newly	RB
cord-322166-ajolu2rh	239	2	emerging	emerge	VBG
cord-322166-ajolu2rh	239	3	virus	virus	NN
cord-322166-ajolu2rh	239	4	strains	strain	NNS
cord-322166-ajolu2rh	239	5	make	make	VBP
cord-322166-ajolu2rh	239	6	the	the	DT
cord-322166-ajolu2rh	239	7	choice	choice	NN
cord-322166-ajolu2rh	239	8	of	of	IN
cord-322166-ajolu2rh	239	9	vaccine	vaccine	NN
cord-322166-ajolu2rh	239	10	strains	strain	NNS
cord-322166-ajolu2rh	239	11	problematic	problematic	JJ
cord-322166-ajolu2rh	239	12	.	.	.
cord-322166-ajolu2rh	240	1	As	as	IN
cord-322166-ajolu2rh	240	2	a	a	DT
cord-322166-ajolu2rh	240	3	result	result	NN
cord-322166-ajolu2rh	240	4	,	,	,
cord-322166-ajolu2rh	240	5	production	production	NN
cord-322166-ajolu2rh	240	6	and	and	CC
cord-322166-ajolu2rh	240	7	deployment	deployment	NN
cord-322166-ajolu2rh	240	8	of	of	IN
cord-322166-ajolu2rh	240	9	vaccine	vaccine	NN
cord-322166-ajolu2rh	240	10	are	be	VBP
cord-322166-ajolu2rh	240	11	of	of	IN
cord-322166-ajolu2rh	240	12	vital	vital	JJ
cord-322166-ajolu2rh	240	13	importance	importance	NN
cord-322166-ajolu2rh	240	14	.	.	.
cord-322166-ajolu2rh	241	1	To	to	IN
cord-322166-ajolu2rh	241	2	date	date	NN
cord-322166-ajolu2rh	241	3	,	,	,
cord-322166-ajolu2rh	241	4	there	there	EX
cord-322166-ajolu2rh	241	5	are	be	VBP
cord-322166-ajolu2rh	241	6	at	at	RB
cord-322166-ajolu2rh	241	7	least	least	RBS
cord-322166-ajolu2rh	241	8	23	23	CD
cord-322166-ajolu2rh	241	9	candidate	candidate	NN
cord-322166-ajolu2rh	241	10	vaccine	vaccine	NN
cord-322166-ajolu2rh	241	11	viruses	virus	NNS
cord-322166-ajolu2rh	241	12	that	that	WDT
cord-322166-ajolu2rh	241	13	can	can	MD
cord-322166-ajolu2rh	241	14	be	be	VB
cord-322166-ajolu2rh	241	15	used	use	VBN
cord-322166-ajolu2rh	241	16	in	in	IN
cord-322166-ajolu2rh	241	17	clinical	clinical	JJ
cord-322166-ajolu2rh	241	18	trials	trial	NNS
cord-322166-ajolu2rh	241	19	and	and	CC
cord-322166-ajolu2rh	241	20	in	in	IN
cord-322166-ajolu2rh	241	21	model	model	NN
cord-322166-ajolu2rh	241	22	systems	system	NNS
cord-322166-ajolu2rh	241	23	of	of	IN
cord-322166-ajolu2rh	241	24	pandemic	pandemic	JJ
cord-322166-ajolu2rh	241	25	vaccine	vaccine	NN
cord-322166-ajolu2rh	241	26	production	production	NN
cord-322166-ajolu2rh	242	1	(	(	-LRB-
cord-322166-ajolu2rh	242	2	Nduati	Nduati	NNP
cord-322166-ajolu2rh	242	3	R	R	NNP
cord-322166-ajolu2rh	242	4	,	,	,
cord-322166-ajolu2rh	242	5	et	et	NNP
cord-322166-ajolu2rh	242	6	al	al	NNP
cord-322166-ajolu2rh	242	7	.	.	NNP
cord-322166-ajolu2rh	242	8	,	,	,
cord-322166-ajolu2rh	242	9	2001	2001	CD
cord-322166-ajolu2rh	242	10	)	)	-RRB-
cord-322166-ajolu2rh	242	11	.	.	.
cord-322166-ajolu2rh	243	1	Based	base	VBN
cord-322166-ajolu2rh	243	2	on	on	IN
cord-322166-ajolu2rh	243	3	specific	specific	JJ
cord-322166-ajolu2rh	243	4	properties	property	NNS
cord-322166-ajolu2rh	243	5	of	of	IN
cord-322166-ajolu2rh	243	6	the	the	DT
cord-322166-ajolu2rh	243	7	H5N1	H5N1	NNP
cord-322166-ajolu2rh	243	8	viruses	virus	NNS
cord-322166-ajolu2rh	243	9	in	in	IN
cord-322166-ajolu2rh	243	10	particular	particular	JJ
cord-322166-ajolu2rh	243	11	geographic	geographic	JJ
cord-322166-ajolu2rh	243	12	areas	area	NNS
cord-322166-ajolu2rh	243	13	,	,	,
cord-322166-ajolu2rh	243	14	using	use	VBG
cord-322166-ajolu2rh	243	15	one	one	CD
cord-322166-ajolu2rh	243	16	or	or	CC
cord-322166-ajolu2rh	243	17	more	more	JJR
cord-322166-ajolu2rh	243	18	of	of	IN
cord-322166-ajolu2rh	243	19	these	these	DT
cord-322166-ajolu2rh	243	20	candidate	candidate	NN
cord-322166-ajolu2rh	243	21	viruses	virus	NNS
cord-322166-ajolu2rh	243	22	for	for	IN
cord-322166-ajolu2rh	243	23	vaccine	vaccine	NN
cord-322166-ajolu2rh	243	24	production	production	NN
cord-322166-ajolu2rh	243	25	should	should	MD
cord-322166-ajolu2rh	243	26	be	be	VB
cord-322166-ajolu2rh	243	27	considered	consider	VBN
cord-322166-ajolu2rh	243	28	.	.	.
cord-322166-ajolu2rh	244	1	Unlike	unlike	IN
cord-322166-ajolu2rh	244	2	seasonal	seasonal	JJ
cord-322166-ajolu2rh	244	3	influenza	influenza	NN
cord-322166-ajolu2rh	244	4	virus	virus	NN
cord-322166-ajolu2rh	244	5	vaccine	vaccine	NN
cord-322166-ajolu2rh	244	6	production	production	NN
cord-322166-ajolu2rh	244	7	,	,	,
cord-322166-ajolu2rh	244	8	using	use	VBG
cord-322166-ajolu2rh	244	9	the	the	DT
cord-322166-ajolu2rh	244	10	wild	wild	JJ
cord-322166-ajolu2rh	244	11	-	-	HYPH
cord-322166-ajolu2rh	244	12	type	type	NN
cord-322166-ajolu2rh	244	13	H5N1	H5N1	NNP
cord-322166-ajolu2rh	244	14	virus	virus	NN
cord-322166-ajolu2rh	244	15	for	for	IN
cord-322166-ajolu2rh	244	16	vaccine	vaccine	NN
cord-322166-ajolu2rh	244	17	production	production	NN
cord-322166-ajolu2rh	244	18	in	in	IN
cord-322166-ajolu2rh	244	19	eggs	egg	NNS
cord-322166-ajolu2rh	244	20	is	be	VBZ
cord-322166-ajolu2rh	244	21	not	not	RB
cord-322166-ajolu2rh	244	22	practical	practical	JJ
cord-322166-ajolu2rh	244	23	due	due	IN
cord-322166-ajolu2rh	244	24	to	to	IN
cord-322166-ajolu2rh	244	25	its	-PRON-	PRP$
cord-322166-ajolu2rh	244	26	high	high	JJ
cord-322166-ajolu2rh	244	27	virulence	virulence	NN
cord-322166-ajolu2rh	244	28	.	.	.
cord-322166-ajolu2rh	245	1	Recent	recent	JJ
cord-322166-ajolu2rh	245	2	data	datum	NNS
cord-322166-ajolu2rh	245	3	also	also	RB
cord-322166-ajolu2rh	245	4	showed	show	VBD
cord-322166-ajolu2rh	245	5	that	that	IN
cord-322166-ajolu2rh	245	6	the	the	DT
cord-322166-ajolu2rh	245	7	prototype	prototype	NN
cord-322166-ajolu2rh	245	8	H5N1	H5N1	NNP
cord-322166-ajolu2rh	245	9	vaccine	vaccine	NN
cord-322166-ajolu2rh	245	10	,	,	,
cord-322166-ajolu2rh	245	11	which	which	WDT
cord-322166-ajolu2rh	245	12	used	use	VBD
cord-322166-ajolu2rh	245	13	a	a	DT
cord-322166-ajolu2rh	245	14	plasmid	plasmid	NN
cord-322166-ajolu2rh	245	15	-	-	HYPH
cord-322166-ajolu2rh	245	16	based	base	VBN
cord-322166-ajolu2rh	245	17	reverse	reverse	JJ
cord-322166-ajolu2rh	245	18	genetics	genetics	NN
cord-322166-ajolu2rh	245	19	system	system	NN
cord-322166-ajolu2rh	245	20	,	,	,
cord-322166-ajolu2rh	245	21	was	be	VBD
cord-322166-ajolu2rh	245	22	poorly	poorly	RB
cord-322166-ajolu2rh	245	23	immunogenic	immunogenic	JJ
cord-322166-ajolu2rh	245	24	(	(	-LRB-
cord-322166-ajolu2rh	245	25	Cheung	Cheung	NNP
cord-322166-ajolu2rh	245	26	C	C	NNP
cord-322166-ajolu2rh	245	27	L	L	NNP
cord-322166-ajolu2rh	245	28	,	,	,
cord-322166-ajolu2rh	245	29	et	et	NNP
cord-322166-ajolu2rh	245	30	al	al	NNP
cord-322166-ajolu2rh	245	31	.	.	NNP
cord-322166-ajolu2rh	245	32	,	,	,
cord-322166-ajolu2rh	245	33	2006	2006	CD
cord-322166-ajolu2rh	245	34	;	;	:
cord-322166-ajolu2rh	245	35	Harvey	Harvey	NNP
cord-322166-ajolu2rh	245	36	R	R	NNP
cord-322166-ajolu2rh	245	37	,	,	,
cord-322166-ajolu2rh	245	38	et	et	NNP
cord-322166-ajolu2rh	245	39	al	al	NNP
cord-322166-ajolu2rh	245	40	.	.	NNP
cord-322166-ajolu2rh	245	41	,	,	,
cord-322166-ajolu2rh	245	42	2008	2008	CD
cord-322166-ajolu2rh	245	43	)	)	-RRB-
cord-322166-ajolu2rh	245	44	.	.	.
cord-322166-ajolu2rh	246	1	Luckily	luckily	RB
cord-322166-ajolu2rh	246	2	,	,	,
cord-322166-ajolu2rh	246	3	it	-PRON-	PRP
cord-322166-ajolu2rh	246	4	was	be	VBD
cord-322166-ajolu2rh	246	5	discovered	discover	VBN
cord-322166-ajolu2rh	246	6	that	that	IN
cord-322166-ajolu2rh	246	7	the	the	DT
cord-322166-ajolu2rh	246	8	addition	addition	NN
cord-322166-ajolu2rh	246	9	of	of	IN
cord-322166-ajolu2rh	246	10	an	an	DT
cord-322166-ajolu2rh	246	11	adjuvant	adjuvant	NN
cord-322166-ajolu2rh	246	12	(	(	-LRB-
cord-322166-ajolu2rh	246	13	e.g.	e.g.	RB
cord-322166-ajolu2rh	246	14	,	,	,
cord-322166-ajolu2rh	246	15	AlPO	AlPO	NNP
cord-322166-ajolu2rh	246	16	4	4	CD
cord-322166-ajolu2rh	246	17	or	or	CC
cord-322166-ajolu2rh	246	18	Iscomatrix	Iscomatrix	NNP
cord-322166-ajolu2rh	246	19	)	)	-RRB-
cord-322166-ajolu2rh	246	20	to	to	IN
cord-322166-ajolu2rh	246	21	this	this	DT
cord-322166-ajolu2rh	246	22	prototype	prototype	NN
cord-322166-ajolu2rh	246	23	vaccine	vaccine	NN
cord-322166-ajolu2rh	246	24	could	could	MD
cord-322166-ajolu2rh	246	25	induce	induce	VB
cord-322166-ajolu2rh	246	26	a	a	DT
cord-322166-ajolu2rh	246	27	clinically	clinically	RB
cord-322166-ajolu2rh	246	28	significant	significant	JJ
cord-322166-ajolu2rh	246	29	protection	protection	NN
cord-322166-ajolu2rh	246	30	in	in	IN
cord-322166-ajolu2rh	246	31	animal	animal	NN
cord-322166-ajolu2rh	246	32	models	model	NNS
cord-322166-ajolu2rh	246	33	(	(	-LRB-
cord-322166-ajolu2rh	246	34	Nolan	Nolan	NNP
cord-322166-ajolu2rh	246	35	T	T	NNP
cord-322166-ajolu2rh	246	36	,	,	,
cord-322166-ajolu2rh	246	37	et	et	NNP
cord-322166-ajolu2rh	246	38	al	al	NNP
cord-322166-ajolu2rh	246	39	.	.	NNP
cord-322166-ajolu2rh	246	40	,	,	,
cord-322166-ajolu2rh	246	41	2008	2008	CD
cord-322166-ajolu2rh	246	42	;	;	:
cord-322166-ajolu2rh	246	43	Rockman	Rockman	NNP
cord-322166-ajolu2rh	246	44	S	S	NNP
cord-322166-ajolu2rh	246	45	,	,	,
cord-322166-ajolu2rh	246	46	et	et	NNP
cord-322166-ajolu2rh	246	47	al	al	NNP
cord-322166-ajolu2rh	246	48	.	.	NNP
cord-322166-ajolu2rh	246	49	,	,	,
cord-322166-ajolu2rh	246	50	2010	2010	CD
cord-322166-ajolu2rh	246	51	)	)	-RRB-
cord-322166-ajolu2rh	246	52	.	.	.
cord-322166-ajolu2rh	247	1	Beyond	beyond	IN
cord-322166-ajolu2rh	247	2	recombinant	recombinant	JJ
cord-322166-ajolu2rh	247	3	or	or	CC
cord-322166-ajolu2rh	247	4	attenuated	attenuated	JJ
cord-322166-ajolu2rh	247	5	vaccines	vaccine	NNS
cord-322166-ajolu2rh	247	6	,	,	,
cord-322166-ajolu2rh	247	7	whole	whole	JJ
cord-322166-ajolu2rh	247	8	inactivated	inactivate	VBN
cord-322166-ajolu2rh	247	9	virus	virus	NN
cord-322166-ajolu2rh	247	10	influenza	influenza	NN
cord-322166-ajolu2rh	247	11	vaccine	vaccine	NN
cord-322166-ajolu2rh	247	12	can	can	MD
cord-322166-ajolu2rh	247	13	also	also	RB
cord-322166-ajolu2rh	247	14	provide	provide	VB
cord-322166-ajolu2rh	247	15	heterosubtypic	heterosubtypic	NNP
cord-322166-ajolu2rh	247	16	cross	cross	NN
cord-322166-ajolu2rh	247	17	-	-	NN
cord-322166-ajolu2rh	247	18	protection	protection	NN
cord-322166-ajolu2rh	247	19	against	against	IN
cord-322166-ajolu2rh	247	20	influenza	influenza	NN
cord-322166-ajolu2rh	247	21	infection	infection	NN
cord-322166-ajolu2rh	247	22	(	(	-LRB-
cord-322166-ajolu2rh	247	23	Budimir	Budimir	NNP
cord-322166-ajolu2rh	247	24	N	N	NNP
cord-322166-ajolu2rh	247	25	,	,	,
cord-322166-ajolu2rh	247	26	et	et	NNP
cord-322166-ajolu2rh	247	27	al	al	NNP
cord-322166-ajolu2rh	247	28	.	.	NNP
cord-322166-ajolu2rh	247	29	,	,	,
cord-322166-ajolu2rh	247	30	2012	2012	CD
cord-322166-ajolu2rh	247	31	)	)	-RRB-
cord-322166-ajolu2rh	247	32	.	.	.
cord-322166-ajolu2rh	248	1	Other	other	JJ
cord-322166-ajolu2rh	248	2	options	option	NNS
cord-322166-ajolu2rh	248	3	that	that	WDT
cord-322166-ajolu2rh	248	4	use	use	VBP
cord-322166-ajolu2rh	248	5	newly	newly	RB
cord-322166-ajolu2rh	248	6	established	establish	VBN
cord-322166-ajolu2rh	248	7	recombinant	recombinant	JJ
cord-322166-ajolu2rh	248	8	adenoviral	adenoviral	JJ
cord-322166-ajolu2rh	248	9	-	-	HYPH
cord-322166-ajolu2rh	248	10	vector	vector	NN
cord-322166-ajolu2rh	248	11	-	-	HYPH
cord-322166-ajolu2rh	248	12	based	base	VBN
cord-322166-ajolu2rh	248	13	vaccines	vaccine	NNS
cord-322166-ajolu2rh	248	14	to	to	TO
cord-322166-ajolu2rh	248	15	express	express	VB
cord-322166-ajolu2rh	248	16	H5	H5	NNP
cord-322166-ajolu2rh	248	17	HA	HA	NNP
cord-322166-ajolu2rh	248	18	or	or	CC
cord-322166-ajolu2rh	248	19	a	a	DT
cord-322166-ajolu2rh	248	20	polyvalent	polyvalent	JJ
cord-322166-ajolu2rh	248	21	DNA	dna	NN
cord-322166-ajolu2rh	248	22	vaccine	vaccine	NN
cord-322166-ajolu2rh	248	23	expressing	express	VBG
cord-322166-ajolu2rh	248	24	HA	HA	NNP
cord-322166-ajolu2rh	248	25	antigens	antigen	NNS
cord-322166-ajolu2rh	248	26	from	from	IN
cord-322166-ajolu2rh	248	27	H5N1	H5N1	NNP
cord-322166-ajolu2rh	248	28	viruses	virus	NNS
cord-322166-ajolu2rh	248	29	have	have	VBP
cord-322166-ajolu2rh	248	30	achieved	achieve	VBN
cord-322166-ajolu2rh	248	31	protective	protective	JJ
cord-322166-ajolu2rh	248	32	antibody	antibody	NN
cord-322166-ajolu2rh	248	33	responses	response	NNS
cord-322166-ajolu2rh	248	34	in	in	IN
cord-322166-ajolu2rh	248	35	animals	animal	NNS
cord-322166-ajolu2rh	248	36	(	(	-LRB-
cord-322166-ajolu2rh	248	37	Hoelscher	Hoelscher	NNP
cord-322166-ajolu2rh	248	38	M	M	NNP
cord-322166-ajolu2rh	248	39	A	A	NNP
cord-322166-ajolu2rh	248	40	,	,	,
cord-322166-ajolu2rh	248	41	et	et	NNP
cord-322166-ajolu2rh	248	42	al	al	NNP
cord-322166-ajolu2rh	248	43	.	.	NNP
cord-322166-ajolu2rh	248	44	,	,	,
cord-322166-ajolu2rh	248	45	2006	2006	CD
cord-322166-ajolu2rh	248	46	;	;	:
cord-322166-ajolu2rh	248	47	Wang	Wang	NNP
cord-322166-ajolu2rh	248	48	S	S	NNP
cord-322166-ajolu2rh	248	49	,	,	,
cord-322166-ajolu2rh	248	50	et	et	NNP
cord-322166-ajolu2rh	248	51	al	al	NNP
cord-322166-ajolu2rh	248	52	.	.	NNP
cord-322166-ajolu2rh	248	53	,	,	,
cord-322166-ajolu2rh	248	54	2011	2011	CD
cord-322166-ajolu2rh	248	55	)	)	-RRB-
cord-322166-ajolu2rh	248	56	.	.	.
cord-322166-ajolu2rh	249	1	Nevertheless	nevertheless	RB
cord-322166-ajolu2rh	249	2	,	,	,
cord-322166-ajolu2rh	249	3	the	the	DT
cord-322166-ajolu2rh	249	4	high	high	JJ
cord-322166-ajolu2rh	249	5	mortality	mortality	NN
cord-322166-ajolu2rh	249	6	and	and	CC
cord-322166-ajolu2rh	249	7	pathogenicity	pathogenicity	NN
cord-322166-ajolu2rh	249	8	of	of	IN
cord-322166-ajolu2rh	249	9	H5N1	H5N1	NNP
cord-322166-ajolu2rh	249	10	viruses	virus	NNS
cord-322166-ajolu2rh	249	11	,	,	,
cord-322166-ajolu2rh	249	12	additional	additional	JJ
cord-322166-ajolu2rh	249	13	development	development	NN
cord-322166-ajolu2rh	249	14	of	of	IN
cord-322166-ajolu2rh	249	15	antiviral	antiviral	JJ
cord-322166-ajolu2rh	249	16	drugs	drug	NNS
cord-322166-ajolu2rh	249	17	and	and	CC
cord-322166-ajolu2rh	249	18	vaccines	vaccine	NNS
cord-322166-ajolu2rh	249	19	,	,	,
cord-322166-ajolu2rh	249	20	and	and	CC
cord-322166-ajolu2rh	249	21	novel	novel	NN
cord-322166-ajolu2rh	249	22	preventive	preventive	JJ
cord-322166-ajolu2rh	249	23	and	and	CC
cord-322166-ajolu2rh	249	24	therapeutic	therapeutic	JJ
cord-322166-ajolu2rh	249	25	strategies	strategy	NNS
cord-322166-ajolu2rh	249	26	are	be	VBP
cord-322166-ajolu2rh	249	27	needed	need	VBN
cord-322166-ajolu2rh	249	28	to	to	TO
cord-322166-ajolu2rh	249	29	protect	protect	VB
cord-322166-ajolu2rh	249	30	the	the	DT
cord-322166-ajolu2rh	249	31	world	world	NN
cord-322166-ajolu2rh	249	32	from	from	IN
cord-322166-ajolu2rh	249	33	a	a	DT
cord-322166-ajolu2rh	249	34	potential	potential	JJ
cord-322166-ajolu2rh	249	35	pandemic	pandemic	NN
cord-322166-ajolu2rh	249	36	.	.	.
cord-322166-ajolu2rh	250	1	History	history	NN
cord-322166-ajolu2rh	250	2	witnessed	witness	VBD
cord-322166-ajolu2rh	250	3	three	three	CD
cord-322166-ajolu2rh	250	4	major	major	JJ
cord-322166-ajolu2rh	250	5	influenza	influenza	NN
cord-322166-ajolu2rh	250	6	pandemics	pandemic	NNS
cord-322166-ajolu2rh	250	7	in	in	IN
cord-322166-ajolu2rh	250	8	the	the	DT
cord-322166-ajolu2rh	250	9	20	20	CD
cord-322166-ajolu2rh	250	10	th	th	XX
cord-322166-ajolu2rh	250	11	century	century	NN
cord-322166-ajolu2rh	250	12	:	:	:
cord-322166-ajolu2rh	251	1	The	the	DT
cord-322166-ajolu2rh	251	2	1918	1918	CD
cord-322166-ajolu2rh	251	3	H1N1	H1N1	NNP
cord-322166-ajolu2rh	251	4	Spanish	Spanish	NNP
cord-322166-ajolu2rh	251	5	Flu	Flu	NNP
cord-322166-ajolu2rh	251	6	,	,	,
cord-322166-ajolu2rh	251	7	1957	1957	CD
cord-322166-ajolu2rh	251	8	H2N2	H2N2	NNP
cord-322166-ajolu2rh	251	9	Asian	Asian	NNP
cord-322166-ajolu2rh	251	10	Flu	Flu	NNP
cord-322166-ajolu2rh	251	11	,	,	,
cord-322166-ajolu2rh	251	12	and	and	CC
cord-322166-ajolu2rh	251	13	1968	1968	CD
cord-322166-ajolu2rh	251	14	Collectively	collectively	RB
cord-322166-ajolu2rh	251	15	,	,	,
cord-322166-ajolu2rh	251	16	these	these	DT
cord-322166-ajolu2rh	251	17	pandemics	pandemic	NNS
cord-322166-ajolu2rh	251	18	caused	cause	VBD
cord-322166-ajolu2rh	251	19	millions	million	NNS
cord-322166-ajolu2rh	251	20	of	of	IN
cord-322166-ajolu2rh	251	21	deaths	death	NNS
cord-322166-ajolu2rh	251	22	and	and	CC
cord-322166-ajolu2rh	251	23	countless	countless	JJ
cord-322166-ajolu2rh	251	24	more	more	JJR
cord-322166-ajolu2rh	251	25	infections	infection	NNS
cord-322166-ajolu2rh	251	26	.	.	.
cord-322166-ajolu2rh	252	1	The	the	DT
cord-322166-ajolu2rh	252	2	highly	highly	RB
cord-322166-ajolu2rh	252	3	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	252	4	influenza	influenza	NN
cord-322166-ajolu2rh	252	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	252	6	,	,	,
cord-322166-ajolu2rh	252	7	despite	despite	IN
cord-322166-ajolu2rh	252	8	its	-PRON-	PRP$
cord-322166-ajolu2rh	252	9	low	low	JJ
cord-322166-ajolu2rh	252	10	morbidity	morbidity	NN
cord-322166-ajolu2rh	252	11	(	(	-LRB-
cord-322166-ajolu2rh	252	12	i.e.	i.e.	FW
cord-322166-ajolu2rh	252	13	,	,	,
cord-322166-ajolu2rh	252	14	low	low	JJ
cord-322166-ajolu2rh	252	15	case	case	NN
cord-322166-ajolu2rh	252	16	incidence	incidence	NN
cord-322166-ajolu2rh	252	17	rate	rate	NN
cord-322166-ajolu2rh	252	18	)	)	-RRB-
cord-322166-ajolu2rh	252	19	and	and	CC
cord-322166-ajolu2rh	252	20	inefficient	inefficient	JJ
cord-322166-ajolu2rh	252	21	human	human	NN
cord-322166-ajolu2rh	252	22	-	-	HYPH
cord-322166-ajolu2rh	252	23	to	to	IN
cord-322166-ajolu2rh	252	24	-	-	HYPH
cord-322166-ajolu2rh	252	25	human	human	JJ
cord-322166-ajolu2rh	252	26	transmission	transmission	NN
cord-322166-ajolu2rh	252	27	,	,	,
cord-322166-ajolu2rh	252	28	remains	remain	VBZ
cord-322166-ajolu2rh	252	29	an	an	DT
cord-322166-ajolu2rh	252	30	important	important	JJ
cord-322166-ajolu2rh	252	31	public	public	JJ
cord-322166-ajolu2rh	252	32	health	health	NN
cord-322166-ajolu2rh	252	33	threat	threat	NN
cord-322166-ajolu2rh	252	34	because	because	IN
cord-322166-ajolu2rh	252	35	of	of	IN
cord-322166-ajolu2rh	252	36	its	-PRON-	PRP$
cord-322166-ajolu2rh	252	37	high	high	JJ
cord-322166-ajolu2rh	252	38	mortality	mortality	NN
cord-322166-ajolu2rh	252	39	.	.	.
cord-322166-ajolu2rh	253	1	Control	control	NN
cord-322166-ajolu2rh	253	2	efforts	effort	NNS
cord-322166-ajolu2rh	253	3	should	should	MD
cord-322166-ajolu2rh	253	4	be	be	VB
cord-322166-ajolu2rh	253	5	coordinated	coordinate	VBN
cord-322166-ajolu2rh	253	6	before	before	IN
cord-322166-ajolu2rh	253	7	this	this	DT
cord-322166-ajolu2rh	253	8	potentially	potentially	RB
cord-322166-ajolu2rh	253	9	dangerous	dangerous	JJ
cord-322166-ajolu2rh	253	10	virus	virus	NN
cord-322166-ajolu2rh	253	11	becomes	become	VBZ
cord-322166-ajolu2rh	253	12	the	the	DT
cord-322166-ajolu2rh	253	13	next	next	JJ
cord-322166-ajolu2rh	253	14	pandemic	pandemic	NN
cord-322166-ajolu2rh	253	15	.	.	.
cord-322166-ajolu2rh	254	1	The	the	DT
cord-322166-ajolu2rh	254	2	last	last	JJ
cord-322166-ajolu2rh	254	3	16	16	CD
cord-322166-ajolu2rh	254	4	years	year	NNS
cord-322166-ajolu2rh	254	5	have	have	VBP
cord-322166-ajolu2rh	254	6	resulted	result	VBN
cord-322166-ajolu2rh	254	7	in	in	IN
cord-322166-ajolu2rh	254	8	a	a	DT
cord-322166-ajolu2rh	254	9	huge	huge	JJ
cord-322166-ajolu2rh	254	10	influx	influx	NN
cord-322166-ajolu2rh	254	11	of	of	IN
cord-322166-ajolu2rh	254	12	research	research	NN
cord-322166-ajolu2rh	254	13	into	into	IN
cord-322166-ajolu2rh	254	14	the	the	DT
cord-322166-ajolu2rh	254	15	replication	replication	NN
cord-322166-ajolu2rh	254	16	and	and	CC
cord-322166-ajolu2rh	254	17	pathogenicity	pathogenicity	NN
cord-322166-ajolu2rh	254	18	of	of	IN
cord-322166-ajolu2rh	254	19	H5N1	H5N1	NNP
cord-322166-ajolu2rh	254	20	,	,	,
cord-322166-ajolu2rh	254	21	but	but	CC
cord-322166-ajolu2rh	254	22	our	-PRON-	PRP$
cord-322166-ajolu2rh	254	23	understanding	understanding	NN
cord-322166-ajolu2rh	254	24	of	of	IN
cord-322166-ajolu2rh	254	25	H5N1	H5N1	NNP
cord-322166-ajolu2rh	254	26	remains	remain	VBZ
cord-322166-ajolu2rh	254	27	incomplete	incomplete	JJ
cord-322166-ajolu2rh	254	28	.	.	.
cord-322166-ajolu2rh	255	1	The	the	DT
cord-322166-ajolu2rh	255	2	recent	recent	JJ
cord-322166-ajolu2rh	255	3	emergence	emergence	NN
cord-322166-ajolu2rh	255	4	of	of	IN
cord-322166-ajolu2rh	255	5	the	the	DT
cord-322166-ajolu2rh	255	6	2009	2009	CD
cord-322166-ajolu2rh	255	7	swine	swine	NN
cord-322166-ajolu2rh	255	8	-	-	HYPH
cord-322166-ajolu2rh	255	9	origin	origin	NN
cord-322166-ajolu2rh	255	10	H1N1	H1N1	NNP
cord-322166-ajolu2rh	255	11	influenza	influenza	NN
cord-322166-ajolu2rh	255	12	underlines	underline	VBZ
cord-322166-ajolu2rh	255	13	the	the	DT
cord-322166-ajolu2rh	255	14	challenges	challenge	NNS
cord-322166-ajolu2rh	255	15	remaining	remain	VBG
cord-322166-ajolu2rh	255	16	to	to	TO
cord-322166-ajolu2rh	255	17	establish	establish	VB
cord-322166-ajolu2rh	255	18	a	a	DT
cord-322166-ajolu2rh	255	19	control	control	NN
cord-322166-ajolu2rh	255	20	network	network	NN
cord-322166-ajolu2rh	255	21	to	to	TO
cord-322166-ajolu2rh	255	22	contain	contain	VB
cord-322166-ajolu2rh	255	23	virus	virus	NN
cord-322166-ajolu2rh	255	24	pandemics	pandemic	NNS
cord-322166-ajolu2rh	255	25	.	.	.
cord-322166-ajolu2rh	256	1	Controlling	control	VBG
cord-322166-ajolu2rh	256	2	the	the	DT
cord-322166-ajolu2rh	256	3	spread	spread	NN
cord-322166-ajolu2rh	256	4	of	of	IN
cord-322166-ajolu2rh	256	5	the	the	DT
cord-322166-ajolu2rh	256	6	influenza	influenza	NN
cord-322166-ajolu2rh	256	7	virus	virus	NN
cord-322166-ajolu2rh	256	8	requires	require	VBZ
cord-322166-ajolu2rh	256	9	a	a	DT
cord-322166-ajolu2rh	256	10	modern	modern	JJ
cord-322166-ajolu2rh	256	11	,	,	,
cord-322166-ajolu2rh	256	12	global	global	JJ
cord-322166-ajolu2rh	256	13	,	,	,
cord-322166-ajolu2rh	256	14	and	and	CC
cord-322166-ajolu2rh	256	15	interlinked	interlink	VBN
cord-322166-ajolu2rh	256	16	cooperative	cooperative	JJ
cord-322166-ajolu2rh	256	17	effort	effort	NN
cord-322166-ajolu2rh	256	18	.	.	.
cord-322166-ajolu2rh	257	1	H5N1	H5N1	NNP
cord-322166-ajolu2rh	257	2	)	)	-RRB-
cord-322166-ajolu2rh	257	3	:	:	:
cord-322166-ajolu2rh	257	4	a	a	DT
cord-322166-ajolu2rh	257	5	threat	threat	NN
cord-322166-ajolu2rh	257	6	to	to	IN
cord-322166-ajolu2rh	257	7	human	human	JJ
cord-322166-ajolu2rh	257	8	health	health	NN
cord-322166-ajolu2rh	257	9	Host	Host	NNP
cord-322166-ajolu2rh	257	10	response	response	NN
cord-322166-ajolu2rh	257	11	to	to	IN
cord-322166-ajolu2rh	257	12	influenza	influenza	NNP
cord-322166-ajolu2rh	257	13	virus	virus	NN
cord-322166-ajolu2rh	257	14	:	:	:
cord-322166-ajolu2rh	257	15	protection	protection	NN
cord-322166-ajolu2rh	257	16	versus	versus	IN
cord-322166-ajolu2rh	257	17	immunopathology	immunopathology	VBG
cord-322166-ajolu2rh	257	18	Innate	innate	JJ
cord-322166-ajolu2rh	257	19	immune	immune	JJ
cord-322166-ajolu2rh	257	20	responses	response	NNS
cord-322166-ajolu2rh	257	21	to	to	TO
cord-322166-ajolu2rh	257	22	influenza	influenza	VB
cord-322166-ajolu2rh	257	23	A	a	DT
cord-322166-ajolu2rh	257	24	H5N1	H5N1	NNP
cord-322166-ajolu2rh	257	25	:	:	:
cord-322166-ajolu2rh	257	26	friend	friend	NN
cord-322166-ajolu2rh	257	27	or	or	CC
cord-322166-ajolu2rh	257	28	foe	foe	NN
cord-322166-ajolu2rh	257	29	?	?	.
cord-322166-ajolu2rh	258	1	Pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	258	2	of	of	IN
cord-322166-ajolu2rh	258	3	avian	avian	JJ
cord-322166-ajolu2rh	258	4	flu	flu	NN
cord-322166-ajolu2rh	258	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	258	6	and	and	CC
cord-322166-ajolu2rh	258	7	SARS	SARS	NNP
cord-322166-ajolu2rh	258	8	Implications	Implications	NNPS
cord-322166-ajolu2rh	258	9	of	of	IN
cord-322166-ajolu2rh	258	10	global	global	JJ
cord-322166-ajolu2rh	258	11	and	and	CC
cord-322166-ajolu2rh	258	12	regional	regional	JJ
cord-322166-ajolu2rh	258	13	patterns	pattern	NNS
cord-322166-ajolu2rh	258	14	of	of	IN
cord-322166-ajolu2rh	258	15	highly	highly	RB
cord-322166-ajolu2rh	258	16	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	258	17	avian	avian	JJ
cord-322166-ajolu2rh	258	18	influenza	influenza	NN
cord-322166-ajolu2rh	258	19	virus	virus	NN
cord-322166-ajolu2rh	258	20	H5N1	H5N1	NNP
cord-322166-ajolu2rh	258	21	clades	clade	NNS
cord-322166-ajolu2rh	258	22	for	for	IN
cord-322166-ajolu2rh	258	23	risk	risk	NN
cord-322166-ajolu2rh	258	24	management	management	NN
cord-322166-ajolu2rh	258	25	Phosphoantigen	Phosphoantigen	NNP
cord-322166-ajolu2rh	258	26	-	-	HYPH
cord-322166-ajolu2rh	258	27	expanded	expand	VBN
cord-322166-ajolu2rh	258	28	human	human	JJ
cord-322166-ajolu2rh	258	29	gammadelta	gammadelta	NNS
cord-322166-ajolu2rh	258	30	T	T	NNP
cord-322166-ajolu2rh	258	31	cells	cell	NNS
cord-322166-ajolu2rh	258	32	display	display	VBP
cord-322166-ajolu2rh	258	33	potent	potent	JJ
cord-322166-ajolu2rh	258	34	cytotoxicity	cytotoxicity	NN
cord-322166-ajolu2rh	258	35	against	against	IN
cord-322166-ajolu2rh	258	36	monocyte	monocyte	NNP
cord-322166-ajolu2rh	258	37	-	-	HYPH
cord-322166-ajolu2rh	258	38	derived	derive	VBN
cord-322166-ajolu2rh	258	39	macrophages	macrophage	NNS
cord-322166-ajolu2rh	258	40	infected	infect	VBN
cord-322166-ajolu2rh	258	41	with	with	IN
cord-322166-ajolu2rh	258	42	human	human	JJ
cord-322166-ajolu2rh	258	43	and	and	CC
cord-322166-ajolu2rh	258	44	avian	avian	JJ
cord-322166-ajolu2rh	258	45	influenza	influenza	NN
cord-322166-ajolu2rh	258	46	viruses	virus	NNS
cord-322166-ajolu2rh	258	47	Vgamma9Vdelta2	Vgamma9Vdelta2	VBZ
cord-322166-ajolu2rh	258	48	T	T	NNP
cord-322166-ajolu2rh	258	49	cells	cell	NNS
cord-322166-ajolu2rh	258	50	to	to	IN
cord-322166-ajolu2rh	258	51	influenza	influenza	VB
cord-322166-ajolu2rh	258	52	A	a	DT
cord-322166-ajolu2rh	258	53	viruses	virus	NNS
cord-322166-ajolu2rh	258	54	Effects	effect	NNS
cord-322166-ajolu2rh	258	55	of	of	IN
cord-322166-ajolu2rh	258	56	receptor	receptor	NN
cord-322166-ajolu2rh	258	57	binding	bind	VBG
cord-322166-ajolu2rh	258	58	specificity	specificity	NN
cord-322166-ajolu2rh	258	59	of	of	IN
cord-322166-ajolu2rh	258	60	avian	avian	JJ
cord-322166-ajolu2rh	258	61	influenza	influenza	NN
cord-322166-ajolu2rh	258	62	virus	virus	NN
cord-322166-ajolu2rh	258	63	on	on	IN
cord-322166-ajolu2rh	258	64	the	the	DT
cord-322166-ajolu2rh	258	65	human	human	JJ
cord-322166-ajolu2rh	258	66	innate	innate	JJ
cord-322166-ajolu2rh	258	67	immune	immune	JJ
cord-322166-ajolu2rh	258	68	response	response	NN
cord-322166-ajolu2rh	258	69	Highly	highly	RB
cord-322166-ajolu2rh	258	70	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	258	71	avian	avian	JJ
cord-322166-ajolu2rh	258	72	influenza	influenza	NN
cord-322166-ajolu2rh	258	73	virus	virus	NN
cord-322166-ajolu2rh	258	74	H5N1	H5N1	NNP
cord-322166-ajolu2rh	258	75	infection	infection	NN
cord-322166-ajolu2rh	258	76	in	in	IN
cord-322166-ajolu2rh	258	77	a	a	DT
cord-322166-ajolu2rh	258	78	long	long	JJ
cord-322166-ajolu2rh	258	79	-	-	HYPH
cord-322166-ajolu2rh	258	80	distance	distance	NN
cord-322166-ajolu2rh	258	81	migrant	migrant	JJ
cord-322166-ajolu2rh	258	82	shorebird	shorebird	NN
cord-322166-ajolu2rh	258	83	under	under	IN
cord-322166-ajolu2rh	258	84	migratory	migratory	JJ
cord-322166-ajolu2rh	258	85	and	and	CC
cord-322166-ajolu2rh	258	86	non	non	JJ
cord-322166-ajolu2rh	258	87	-	-	JJ
cord-322166-ajolu2rh	258	88	migratory	migratory	JJ
cord-322166-ajolu2rh	258	89	states	state	NNS
cord-322166-ajolu2rh	258	90	Pathogenesis	Pathogenesis	NNP
cord-322166-ajolu2rh	258	91	of	of	IN
cord-322166-ajolu2rh	258	92	influenza	influenza	NN
cord-322166-ajolu2rh	258	93	A	a	NN
cord-322166-ajolu2rh	259	1	(	(	-LRB-
cord-322166-ajolu2rh	259	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	259	3	)	)	-RRB-
cord-322166-ajolu2rh	259	4	virus	virus	NN
cord-322166-ajolu2rh	259	5	infection	infection	NN
cord-322166-ajolu2rh	259	6	in	in	IN
cord-322166-ajolu2rh	259	7	a	a	DT
cord-322166-ajolu2rh	259	8	primate	primate	JJ
cord-322166-ajolu2rh	259	9	model	model	NN
cord-322166-ajolu2rh	260	1	The	the	DT
cord-322166-ajolu2rh	260	2	accumulation	accumulation	NN
cord-322166-ajolu2rh	260	3	of	of	IN
cord-322166-ajolu2rh	260	4	influenza	influenza	NN
cord-322166-ajolu2rh	260	5	A	a	DT
cord-322166-ajolu2rh	260	6	virus	virus	NN
cord-322166-ajolu2rh	260	7	segment	segment	NN
cord-322166-ajolu2rh	260	8	7	7	CD
cord-322166-ajolu2rh	260	9	spliced	spliced	JJ
cord-322166-ajolu2rh	260	10	mRNAs	mRNAs	NNPS
cord-322166-ajolu2rh	260	11	is	be	VBZ
cord-322166-ajolu2rh	260	12	regulated	regulate	VBN
cord-322166-ajolu2rh	260	13	by	by	IN
cord-322166-ajolu2rh	260	14	the	the	DT
cord-322166-ajolu2rh	260	15	NS1	ns1	NN
cord-322166-ajolu2rh	260	16	protein	protein	NN
cord-322166-ajolu2rh	260	17	Pre	pre	NN
cord-322166-ajolu2rh	260	18	-	-	JJ
cord-322166-ajolu2rh	260	19	pandemic	pandemic	JJ
cord-322166-ajolu2rh	260	20	and	and	CC
cord-322166-ajolu2rh	260	21	pandemic	pandemic	NN
cord-322166-ajolu2rh	260	22	influenza	influenza	NN
cord-322166-ajolu2rh	260	23	vaccines	vaccine	NNS
cord-322166-ajolu2rh	260	24	H5N1	H5N1	NNP
cord-322166-ajolu2rh	260	25	Avian	avian	JJ
cord-322166-ajolu2rh	260	26	influenza	influenza	NN
cord-322166-ajolu2rh	260	27	:	:	:
cord-322166-ajolu2rh	260	28	preventive	preventive	JJ
cord-322166-ajolu2rh	260	29	and	and	CC
cord-322166-ajolu2rh	260	30	therapeutic	therapeutic	JJ
cord-322166-ajolu2rh	260	31	strategies	strategy	NNS
cord-322166-ajolu2rh	260	32	against	against	IN
cord-322166-ajolu2rh	260	33	a	a	DT
cord-322166-ajolu2rh	260	34	pandemic	pandemic	NN
cord-322166-ajolu2rh	260	35	Analysis	analysis	NN
cord-322166-ajolu2rh	260	36	of	of	IN
cord-322166-ajolu2rh	260	37	cytokine	cytokine	JJ
cord-322166-ajolu2rh	260	38	secretion	secretion	NN
cord-322166-ajolu2rh	260	39	from	from	IN
cord-322166-ajolu2rh	260	40	human	human	JJ
cord-322166-ajolu2rh	260	41	plasmacytoid	plasmacytoid	NNP
cord-322166-ajolu2rh	260	42	dendritic	dendritic	JJ
cord-322166-ajolu2rh	260	43	cells	cell	NNS
cord-322166-ajolu2rh	260	44	infected	infect	VBN
cord-322166-ajolu2rh	260	45	with	with	IN
cord-322166-ajolu2rh	260	46	H5N1	H5N1	NNP
cord-322166-ajolu2rh	260	47	or	or	CC
cord-322166-ajolu2rh	260	48	low	low	JJ
cord-322166-ajolu2rh	260	49	-	-	HYPH
cord-322166-ajolu2rh	260	50	pathogenicity	pathogenicity	NN
cord-322166-ajolu2rh	260	51	influenza	influenza	NN
cord-322166-ajolu2rh	260	52	viruses	virus	NNS
cord-322166-ajolu2rh	261	1	Lethal	lethal	JJ
cord-322166-ajolu2rh	261	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	261	3	influenza	influenza	NN
cord-322166-ajolu2rh	261	4	viruses	virus	NNS
cord-322166-ajolu2rh	261	5	escape	escape	VBP
cord-322166-ajolu2rh	261	6	host	host	NN
cord-322166-ajolu2rh	261	7	anti	anti	JJ
cord-322166-ajolu2rh	261	8	-	-	JJ
cord-322166-ajolu2rh	261	9	viral	viral	JJ
cord-322166-ajolu2rh	261	10	cytokine	cytokine	NN
cord-322166-ajolu2rh	261	11	responses	response	NNS
cord-322166-ajolu2rh	261	12	New	New	NNP
cord-322166-ajolu2rh	261	13	Aspect	aspect	NN
cord-322166-ajolu2rh	261	14	of	of	IN
cord-322166-ajolu2rh	261	15	Influenza	Influenza	NNP
cord-322166-ajolu2rh	261	16	Viruses	virus	NNS
cord-322166-ajolu2rh	262	1	Lethal	lethal	JJ
cord-322166-ajolu2rh	263	1	avian	avian	JJ
cord-322166-ajolu2rh	263	2	influenza	influenza	NN
cord-322166-ajolu2rh	263	3	A	A	NNP
cord-322166-ajolu2rh	263	4	(	(	-LRB-
cord-322166-ajolu2rh	263	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	263	6	)	)	-RRB-
cord-322166-ajolu2rh	263	7	infection	infection	NN
cord-322166-ajolu2rh	263	8	in	in	IN
cord-322166-ajolu2rh	263	9	a	a	DT
cord-322166-ajolu2rh	263	10	pregnant	pregnant	JJ
cord-322166-ajolu2rh	263	11	woman	woman	NN
cord-322166-ajolu2rh	263	12	in	in	IN
cord-322166-ajolu2rh	263	13	Anhui	Anhui	NNP
cord-322166-ajolu2rh	263	14	Province	Province	NNP
cord-322166-ajolu2rh	263	15	,	,	,
cord-322166-ajolu2rh	263	16	China	China	NNP
cord-322166-ajolu2rh	263	17	Airway	Airway	NNP
cord-322166-ajolu2rh	263	18	immune	immune	JJ
cord-322166-ajolu2rh	263	19	homeostasis	homeostasis	NN
cord-322166-ajolu2rh	263	20	and	and	CC
cord-322166-ajolu2rh	263	21	implications	implication	NNS
cord-322166-ajolu2rh	263	22	for	for	IN
cord-322166-ajolu2rh	263	23	influenza	influenza	NN
cord-322166-ajolu2rh	263	24	-	-	HYPH
cord-322166-ajolu2rh	263	25	induced	induce	VBN
cord-322166-ajolu2rh	263	26	inflammation	inflammation	NN
cord-322166-ajolu2rh	264	1	A	a	DT
cord-322166-ajolu2rh	264	2	commercial	commercial	JJ
cord-322166-ajolu2rh	264	3	ELISA	ELISA	NNP
cord-322166-ajolu2rh	264	4	detects	detect	VBZ
cord-322166-ajolu2rh	264	5	high	high	JJ
cord-322166-ajolu2rh	264	6	levels	level	NNS
cord-322166-ajolu2rh	264	7	of	of	IN
cord-322166-ajolu2rh	264	8	human	human	JJ
cord-322166-ajolu2rh	264	9	H5	H5	NNP
cord-322166-ajolu2rh	264	10	antibody	antibody	NN
cord-322166-ajolu2rh	264	11	but	but	CC
cord-322166-ajolu2rh	264	12	cross	cross	NN
cord-322166-ajolu2rh	264	13	-	-	JJ
cord-322166-ajolu2rh	264	14	reacts	react	VBZ
cord-322166-ajolu2rh	264	15	with	with	IN
cord-322166-ajolu2rh	264	16	influenza	influenza	NN
cord-322166-ajolu2rh	264	17	A	a	DT
cord-322166-ajolu2rh	264	18	antibodies	antibody	NNS
cord-322166-ajolu2rh	264	19	Structure	structure	NN
cord-322166-ajolu2rh	264	20	and	and	CC
cord-322166-ajolu2rh	264	21	receptor	receptor	NN
cord-322166-ajolu2rh	264	22	specificity	specificity	NN
cord-322166-ajolu2rh	264	23	of	of	IN
cord-322166-ajolu2rh	264	24	the	the	DT
cord-322166-ajolu2rh	264	25	hemagglutinin	hemagglutinin	NN
cord-322166-ajolu2rh	264	26	from	from	IN
cord-322166-ajolu2rh	264	27	an	an	DT
cord-322166-ajolu2rh	264	28	H5N1	H5N1	NNP
cord-322166-ajolu2rh	264	29	influenza	influenza	NN
cord-322166-ajolu2rh	264	30	virus	virus	NN
cord-322166-ajolu2rh	264	31	Immunostimulatory	Immunostimulatory	NNP
cord-322166-ajolu2rh	264	32	motifs	motif	NNS
cord-322166-ajolu2rh	264	33	enhance	enhance	VBP
cord-322166-ajolu2rh	264	34	antiviral	antiviral	JJ
cord-322166-ajolu2rh	264	35	siRNAs	siRNAs	NNP
cord-322166-ajolu2rh	264	36	targeting	target	VBG
cord-322166-ajolu2rh	264	37	highly	highly	RB
cord-322166-ajolu2rh	264	38	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	264	39	avian	avian	JJ
cord-322166-ajolu2rh	264	40	influenza	influenza	NN
cord-322166-ajolu2rh	264	41	H5N1	H5N1	NNP
cord-322166-ajolu2rh	264	42	Avian	avian	JJ
cord-322166-ajolu2rh	264	43	influenza	influenza	NN
cord-322166-ajolu2rh	264	44	:	:	:
cord-322166-ajolu2rh	264	45	our	-PRON-	PRP$
cord-322166-ajolu2rh	264	46	current	current	JJ
cord-322166-ajolu2rh	264	47	understanding	understanding	NN
cord-322166-ajolu2rh	264	48	Immunology	Immunology	NNP
cord-322166-ajolu2rh	264	49	of	of	IN
cord-322166-ajolu2rh	264	50	avian	avian	JJ
cord-322166-ajolu2rh	264	51	influenza	influenza	NN
cord-322166-ajolu2rh	264	52	virus	virus	NN
cord-322166-ajolu2rh	264	53	:	:	:
cord-322166-ajolu2rh	264	54	a	a	DT
cord-322166-ajolu2rh	264	55	review	review	NN
cord-322166-ajolu2rh	265	1	A	a	DT
cord-322166-ajolu2rh	265	2	single	single	JJ
cord-322166-ajolu2rh	265	3	amino	amino	NN
cord-322166-ajolu2rh	265	4	acid	acid	NN
cord-322166-ajolu2rh	265	5	in	in	IN
cord-322166-ajolu2rh	265	6	the	the	DT
cord-322166-ajolu2rh	265	7	PB2	PB2	NNP
cord-322166-ajolu2rh	265	8	gene	gene	NN
cord-322166-ajolu2rh	265	9	of	of	IN
cord-322166-ajolu2rh	265	10	influenza	influenza	NN
cord-322166-ajolu2rh	265	11	A	a	DT
cord-322166-ajolu2rh	265	12	virus	virus	NN
cord-322166-ajolu2rh	265	13	is	be	VBZ
cord-322166-ajolu2rh	265	14	a	a	DT
cord-322166-ajolu2rh	265	15	determinant	determinant	NN
cord-322166-ajolu2rh	265	16	of	of	IN
cord-322166-ajolu2rh	265	17	host	host	NN
cord-322166-ajolu2rh	265	18	range	range	NN
cord-322166-ajolu2rh	265	19	Characterization	characterization	NN
cord-322166-ajolu2rh	265	20	of	of	IN
cord-322166-ajolu2rh	265	21	an	an	DT
cord-322166-ajolu2rh	265	22	avian	avian	JJ
cord-322166-ajolu2rh	265	23	influenza	influenza	NN
cord-322166-ajolu2rh	265	24	A	a	NN
cord-322166-ajolu2rh	265	25	(	(	-LRB-
cord-322166-ajolu2rh	265	26	H5N1	H5N1	NNP
cord-322166-ajolu2rh	265	27	)	)	-RRB-
cord-322166-ajolu2rh	265	28	virus	virus	NN
cord-322166-ajolu2rh	265	29	isolated	isolate	VBN
cord-322166-ajolu2rh	265	30	from	from	IN
cord-322166-ajolu2rh	265	31	a	a	DT
cord-322166-ajolu2rh	265	32	child	child	NN
cord-322166-ajolu2rh	265	33	with	with	IN
cord-322166-ajolu2rh	265	34	a	a	DT
cord-322166-ajolu2rh	265	35	fatal	fatal	JJ
cord-322166-ajolu2rh	265	36	respiratory	respiratory	JJ
cord-322166-ajolu2rh	265	37	illness	illness	NN
cord-322166-ajolu2rh	265	38	Characteristics	characteristic	NNS
cord-322166-ajolu2rh	265	39	of	of	IN
cord-322166-ajolu2rh	265	40	stork	stork	NN
cord-322166-ajolu2rh	265	41	feces	fece	NNS
cord-322166-ajolu2rh	265	42	-	-	:
cord-322166-ajolu2rh	265	43	derived	derive	VBN
cord-322166-ajolu2rh	265	44	H5N1	H5N1	NNP
cord-322166-ajolu2rh	265	45	viruses	virus	NNS
cord-322166-ajolu2rh	265	46	that	that	WDT
cord-322166-ajolu2rh	265	47	are	be	VBP
cord-322166-ajolu2rh	265	48	preferentially	preferentially	RB
cord-322166-ajolu2rh	265	49	transmitted	transmit	VBN
cord-322166-ajolu2rh	265	50	to	to	IN
cord-322166-ajolu2rh	265	51	primary	primary	JJ
cord-322166-ajolu2rh	265	52	human	human	JJ
cord-322166-ajolu2rh	265	53	airway	airway	NN
cord-322166-ajolu2rh	265	54	epithelial	epithelial	JJ
cord-322166-ajolu2rh	265	55	cells	cell	NNS
cord-322166-ajolu2rh	266	1	Inhibition	inhibition	NN
cord-322166-ajolu2rh	266	2	of	of	IN
cord-322166-ajolu2rh	266	3	autophagy	autophagy	NN
cord-322166-ajolu2rh	266	4	ameliorates	ameliorate	VBZ
cord-322166-ajolu2rh	266	5	acute	acute	JJ
cord-322166-ajolu2rh	266	6	lung	lung	NN
cord-322166-ajolu2rh	266	7	injury	injury	NN
cord-322166-ajolu2rh	266	8	caused	cause	VBN
cord-322166-ajolu2rh	266	9	by	by	IN
cord-322166-ajolu2rh	266	10	avian	avian	JJ
cord-322166-ajolu2rh	266	11	influenza	influenza	NN
cord-322166-ajolu2rh	266	12	A	a	DT
cord-322166-ajolu2rh	266	13	H5N1	H5N1	NNP
cord-322166-ajolu2rh	266	14	infection	infection	NN
cord-322166-ajolu2rh	266	15	Role	role	NN
cord-322166-ajolu2rh	266	16	of	of	IN
cord-322166-ajolu2rh	266	17	host	host	NN
cord-322166-ajolu2rh	266	18	cytokine	cytokine	NN
cord-322166-ajolu2rh	266	19	responses	response	NNS
cord-322166-ajolu2rh	266	20	in	in	IN
cord-322166-ajolu2rh	266	21	the	the	DT
cord-322166-ajolu2rh	266	22	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	266	23	of	of	IN
cord-322166-ajolu2rh	266	24	avian	avian	JJ
cord-322166-ajolu2rh	266	25	H5N1	H5N1	NNP
cord-322166-ajolu2rh	266	26	influenza	influenza	NN
cord-322166-ajolu2rh	266	27	viruses	virus	NNS
cord-322166-ajolu2rh	266	28	in	in	IN
cord-322166-ajolu2rh	266	29	mice	mouse	NNS
cord-322166-ajolu2rh	267	1	An	an	DT
cord-322166-ajolu2rh	267	2	Overview	Overview	NNP
cord-322166-ajolu2rh	267	3	of	of	IN
cord-322166-ajolu2rh	267	4	the	the	DT
cord-322166-ajolu2rh	267	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	267	6	Virus	Virus	NNP
cord-322166-ajolu2rh	267	7	Virologica	Virologica	NNP
cord-322166-ajolu2rh	268	1	Sinica|www	Sinica|www	NNP
cord-322166-ajolu2rh	268	2	Early	early	JJ
cord-322166-ajolu2rh	268	3	control	control	NN
cord-322166-ajolu2rh	268	4	of	of	IN
cord-322166-ajolu2rh	268	5	H5N1	H5N1	NNP
cord-322166-ajolu2rh	268	6	influenza	influenza	NN
cord-322166-ajolu2rh	268	7	virus	virus	NN
cord-322166-ajolu2rh	268	8	replication	replication	NN
cord-322166-ajolu2rh	268	9	by	by	IN
cord-322166-ajolu2rh	268	10	the	the	DT
cord-322166-ajolu2rh	268	11	type	type	NN
cord-322166-ajolu2rh	269	1	I	-PRON-	PRP
cord-322166-ajolu2rh	270	1	interferon	interferon	NNP
cord-322166-ajolu2rh	270	2	response	response	NN
cord-322166-ajolu2rh	270	3	in	in	IN
cord-322166-ajolu2rh	270	4	mice	mouse	NNS
cord-322166-ajolu2rh	270	5	Generation	generation	NN
cord-322166-ajolu2rh	270	6	and	and	CC
cord-322166-ajolu2rh	270	7	comprehensive	comprehensive	JJ
cord-322166-ajolu2rh	270	8	analysis	analysis	NN
cord-322166-ajolu2rh	270	9	of	of	IN
cord-322166-ajolu2rh	270	10	an	an	DT
cord-322166-ajolu2rh	270	11	influenza	influenza	NN
cord-322166-ajolu2rh	270	12	virus	virus	NN
cord-322166-ajolu2rh	270	13	polymerase	polymerase	NN
cord-322166-ajolu2rh	270	14	cellular	cellular	JJ
cord-322166-ajolu2rh	270	15	interaction	interaction	NN
cord-322166-ajolu2rh	270	16	network	network	NN
cord-322166-ajolu2rh	270	17	Human	Human	NNP
cord-322166-ajolu2rh	270	18	H5N1	H5N1	NNP
cord-322166-ajolu2rh	270	19	influenza	influenza	NN
cord-322166-ajolu2rh	270	20	:	:	:
cord-322166-ajolu2rh	270	21	current	current	JJ
cord-322166-ajolu2rh	270	22	insight	insight	NN
cord-322166-ajolu2rh	270	23	into	into	IN
cord-322166-ajolu2rh	270	24	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	270	25	Highly	highly	RB
cord-322166-ajolu2rh	270	26	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	270	27	avian	avian	JJ
cord-322166-ajolu2rh	270	28	influenza	influenza	NN
cord-322166-ajolu2rh	270	29	H5N1	H5N1	NNP
cord-322166-ajolu2rh	270	30	virus	virus	NN
cord-322166-ajolu2rh	270	31	in	in	IN
cord-322166-ajolu2rh	270	32	cats	cat	NNS
cord-322166-ajolu2rh	270	33	and	and	CC
cord-322166-ajolu2rh	270	34	other	other	JJ
cord-322166-ajolu2rh	270	35	carnivores	carnivore	NNS
cord-322166-ajolu2rh	271	1	Extrapulmonary	extrapulmonary	JJ
cord-322166-ajolu2rh	271	2	tissue	tissue	NN
cord-322166-ajolu2rh	271	3	responses	response	NNS
cord-322166-ajolu2rh	271	4	in	in	IN
cord-322166-ajolu2rh	271	5	cynomolgus	cynomolgus	JJ
cord-322166-ajolu2rh	271	6	macaques	macaque	NNS
cord-322166-ajolu2rh	271	7	(	(	-LRB-
cord-322166-ajolu2rh	271	8	Macaca	Macaca	NNP
cord-322166-ajolu2rh	271	9	fascicularis	fascicularis	NNP
cord-322166-ajolu2rh	271	10	)	)	-RRB-
cord-322166-ajolu2rh	271	11	infected	infect	VBN
cord-322166-ajolu2rh	271	12	with	with	IN
cord-322166-ajolu2rh	271	13	highly	highly	RB
cord-322166-ajolu2rh	271	14	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	271	15	avian	avian	JJ
cord-322166-ajolu2rh	271	16	influenza	influenza	NN
cord-322166-ajolu2rh	271	17	A	a	NN
cord-322166-ajolu2rh	271	18	(	(	-LRB-
cord-322166-ajolu2rh	271	19	H5N1	H5N1	NNP
cord-322166-ajolu2rh	271	20	)	)	-RRB-
cord-322166-ajolu2rh	271	21	virus	virus	NN
cord-322166-ajolu2rh	272	1	The	the	DT
cord-322166-ajolu2rh	272	2	aminobisphosphonate	aminobisphosphonate	NN
cord-322166-ajolu2rh	272	3	pamidronate	pamidronate	NNP
cord-322166-ajolu2rh	272	4	controls	control	NNS
cord-322166-ajolu2rh	272	5	influenza	influenza	NN
cord-322166-ajolu2rh	272	6	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	272	7	by	by	IN
cord-322166-ajolu2rh	272	8	expanding	expand	VBG
cord-322166-ajolu2rh	272	9	a	a	DT
cord-322166-ajolu2rh	272	10	gammadelta	gammadelta	NNP
cord-322166-ajolu2rh	272	11	T	t	NN
cord-322166-ajolu2rh	272	12	cell	cell	NN
cord-322166-ajolu2rh	272	13	population	population	NN
cord-322166-ajolu2rh	272	14	in	in	IN
cord-322166-ajolu2rh	272	15	humanized	humanized	JJ
cord-322166-ajolu2rh	272	16	mice	mouse	NNS
cord-322166-ajolu2rh	273	1	Probable	probable	JJ
cord-322166-ajolu2rh	273	2	person	person	NN
cord-322166-ajolu2rh	273	3	-	-	HYPH
cord-322166-ajolu2rh	273	4	toperson	toperson	NN
cord-322166-ajolu2rh	273	5	transmission	transmission	NN
cord-322166-ajolu2rh	273	6	of	of	IN
cord-322166-ajolu2rh	273	7	avian	avian	JJ
cord-322166-ajolu2rh	273	8	influenza	influenza	NN
cord-322166-ajolu2rh	273	9	A	a	NN
cord-322166-ajolu2rh	273	10	(	(	-LRB-
cord-322166-ajolu2rh	273	11	H5N1	H5N1	NNP
cord-322166-ajolu2rh	273	12	)	)	-RRB-
cord-322166-ajolu2rh	273	13	Highly	highly	RB
cord-322166-ajolu2rh	273	14	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	273	15	avian	avian	JJ
cord-322166-ajolu2rh	273	16	influenza	influenza	NN
cord-322166-ajolu2rh	273	17	(	(	-LRB-
cord-322166-ajolu2rh	273	18	H5N1	H5N1	NNP
cord-322166-ajolu2rh	273	19	)	)	-RRB-
cord-322166-ajolu2rh	273	20	:	:	:
cord-322166-ajolu2rh	274	1	pathways	pathway	NNS
cord-322166-ajolu2rh	274	2	of	of	IN
cord-322166-ajolu2rh	274	3	exposure	exposure	NN
cord-322166-ajolu2rh	274	4	at	at	IN
cord-322166-ajolu2rh	274	5	the	the	DT
cord-322166-ajolu2rh	274	6	animal	animal	NN
cord-322166-ajolu2rh	274	7	-	-	HYPH
cord-322166-ajolu2rh	274	8	human	human	NN
cord-322166-ajolu2rh	274	9	interface	interface	NN
cord-322166-ajolu2rh	274	10	,	,	,
cord-322166-ajolu2rh	274	11	a	a	DT
cord-322166-ajolu2rh	274	12	systematic	systematic	JJ
cord-322166-ajolu2rh	274	13	review	review	NN
cord-322166-ajolu2rh	275	1	H5N1	H5N1	NNP
cord-322166-ajolu2rh	275	2	Virus	Virus	NNP
cord-322166-ajolu2rh	275	3	Attachment	Attachment	NNP
cord-322166-ajolu2rh	275	4	to	to	IN
cord-322166-ajolu2rh	275	5	Lower	lower	VB
cord-322166-ajolu2rh	275	6	Respiratory	respiratory	JJ
cord-322166-ajolu2rh	275	7	Tract	tract	NN
cord-322166-ajolu2rh	275	8	Human	Human	NNP
cord-322166-ajolu2rh	275	9	and	and	CC
cord-322166-ajolu2rh	275	10	avian	avian	JJ
cord-322166-ajolu2rh	275	11	influenza	influenza	NN
cord-322166-ajolu2rh	275	12	viruses	virus	NNS
cord-322166-ajolu2rh	275	13	target	target	VBP
cord-322166-ajolu2rh	275	14	different	different	JJ
cord-322166-ajolu2rh	275	15	cells	cell	NNS
cord-322166-ajolu2rh	275	16	in	in	IN
cord-322166-ajolu2rh	275	17	the	the	DT
cord-322166-ajolu2rh	275	18	lower	low	JJR
cord-322166-ajolu2rh	275	19	respiratory	respiratory	JJ
cord-322166-ajolu2rh	275	20	tract	tract	NN
cord-322166-ajolu2rh	275	21	of	of	IN
cord-322166-ajolu2rh	275	22	humans	human	NNS
cord-322166-ajolu2rh	275	23	and	and	CC
cord-322166-ajolu2rh	275	24	other	other	JJ
cord-322166-ajolu2rh	275	25	mammals	mammal	NNS
cord-322166-ajolu2rh	275	26	Ecology	Ecology	NNP
cord-322166-ajolu2rh	275	27	of	of	IN
cord-322166-ajolu2rh	275	28	avian	avian	JJ
cord-322166-ajolu2rh	275	29	influenza	influenza	NN
cord-322166-ajolu2rh	275	30	viruses	virus	NNS
cord-322166-ajolu2rh	275	31	in	in	IN
cord-322166-ajolu2rh	275	32	a	a	DT
cord-322166-ajolu2rh	275	33	changing	change	VBG
cord-322166-ajolu2rh	275	34	world	world	NN
cord-322166-ajolu2rh	275	35	Quail	Quail	NNP
cord-322166-ajolu2rh	275	36	carry	carry	VB
cord-322166-ajolu2rh	275	37	sialic	sialic	JJ
cord-322166-ajolu2rh	275	38	acid	acid	NN
cord-322166-ajolu2rh	275	39	receptors	receptor	NNS
cord-322166-ajolu2rh	275	40	compatible	compatible	JJ
cord-322166-ajolu2rh	275	41	with	with	IN
cord-322166-ajolu2rh	275	42	binding	binding	NN
cord-322166-ajolu2rh	275	43	of	of	IN
cord-322166-ajolu2rh	275	44	avian	avian	JJ
cord-322166-ajolu2rh	275	45	and	and	CC
cord-322166-ajolu2rh	275	46	human	human	JJ
cord-322166-ajolu2rh	275	47	influenza	influenza	NN
cord-322166-ajolu2rh	275	48	viruses	viruse	VBZ
cord-322166-ajolu2rh	275	49	Avian	avian	JJ
cord-322166-ajolu2rh	275	50	influenza	influenza	NN
cord-322166-ajolu2rh	275	51	H5N1	H5N1	NNP
cord-322166-ajolu2rh	276	1	an	an	DT
cord-322166-ajolu2rh	276	2	update	update	NN
cord-322166-ajolu2rh	276	3	on	on	IN
cord-322166-ajolu2rh	276	4	molecular	molecular	JJ
cord-322166-ajolu2rh	276	5	pathogensis	pathogensis	NNP
cord-322166-ajolu2rh	276	6	Differentiated	Differentiated	NNP
cord-322166-ajolu2rh	276	7	human	human	JJ
cord-322166-ajolu2rh	276	8	alveolar	alveolar	NN
cord-322166-ajolu2rh	276	9	type	type	NN
cord-322166-ajolu2rh	276	10	II	ii	CD
cord-322166-ajolu2rh	276	11	cells	cell	NNS
cord-322166-ajolu2rh	276	12	secrete	secrete	VBP
cord-322166-ajolu2rh	276	13	antiviral	antiviral	JJ
cord-322166-ajolu2rh	277	1	IL-29	IL-29	NNP
cord-322166-ajolu2rh	277	2	(	(	-LRB-
cord-322166-ajolu2rh	277	3	IFN	IFN	NNP
cord-322166-ajolu2rh	277	4	-	-	HYPH
cord-322166-ajolu2rh	277	5	lambda	lambda	NNP
cord-322166-ajolu2rh	277	6	1	1	CD
cord-322166-ajolu2rh	277	7	)	)	-RRB-
cord-322166-ajolu2rh	277	8	in	in	IN
cord-322166-ajolu2rh	277	9	response	response	NN
cord-322166-ajolu2rh	277	10	to	to	TO
cord-322166-ajolu2rh	277	11	influenza	influenza	VB
cord-322166-ajolu2rh	277	12	A	a	DT
cord-322166-ajolu2rh	277	13	infection	infection	NN
cord-322166-ajolu2rh	277	14	Polyvalent	Polyvalent	NNP
cord-322166-ajolu2rh	277	15	DNA	DNA	NNP
cord-322166-ajolu2rh	278	1	vaccines	vaccine	NNS
cord-322166-ajolu2rh	278	2	expressing	express	VBG
cord-322166-ajolu2rh	278	3	HA	HA	NNP
cord-322166-ajolu2rh	278	4	antigens	antigen	NNS
cord-322166-ajolu2rh	278	5	of	of	IN
cord-322166-ajolu2rh	278	6	H5N1	H5N1	NNP
cord-322166-ajolu2rh	278	7	influenza	influenza	NN
cord-322166-ajolu2rh	278	8	viruses	viruse	VBZ
cord-322166-ajolu2rh	278	9	with	with	IN
cord-322166-ajolu2rh	278	10	an	an	DT
cord-322166-ajolu2rh	278	11	optimized	optimize	VBN
cord-322166-ajolu2rh	278	12	leader	leader	NN
cord-322166-ajolu2rh	278	13	sequence	sequence	NN
cord-322166-ajolu2rh	278	14	elicit	elicit	VB
cord-322166-ajolu2rh	278	15	cross	cross	JJ
cord-322166-ajolu2rh	278	16	-	-	JJ
cord-322166-ajolu2rh	278	17	protective	protective	JJ
cord-322166-ajolu2rh	278	18	antibody	antibody	NN
cord-322166-ajolu2rh	278	19	responses	response	NNS
cord-322166-ajolu2rh	278	20	NP	NP	NNP
cord-322166-ajolu2rh	278	21	,	,	,
cord-322166-ajolu2rh	278	22	PB1	pb1	NN
cord-322166-ajolu2rh	278	23	and	and	CC
cord-322166-ajolu2rh	278	24	PB2	PB2	NNP
cord-322166-ajolu2rh	278	25	viral	viral	JJ
cord-322166-ajolu2rh	278	26	genes	gene	NNS
cord-322166-ajolu2rh	278	27	contribute	contribute	VBP
cord-322166-ajolu2rh	278	28	to	to	IN
cord-322166-ajolu2rh	278	29	altered	alter	VBN
cord-322166-ajolu2rh	278	30	replication	replication	NN
cord-322166-ajolu2rh	278	31	of	of	IN
cord-322166-ajolu2rh	278	32	H5N1	H5N1	NNP
cord-322166-ajolu2rh	278	33	avian	avian	JJ
cord-322166-ajolu2rh	278	34	influenza	influenza	NN
cord-322166-ajolu2rh	278	35	viruses	virus	NNS
cord-322166-ajolu2rh	278	36	in	in	IN
cord-322166-ajolu2rh	278	37	chickens	chicken	NNS
cord-322166-ajolu2rh	278	38	The	the	DT
cord-322166-ajolu2rh	278	39	changing	change	VBG
cord-322166-ajolu2rh	278	40	nature	nature	NN
cord-322166-ajolu2rh	278	41	of	of	IN
cord-322166-ajolu2rh	278	42	avian	avian	JJ
cord-322166-ajolu2rh	278	43	influenza	influenza	NN
cord-322166-ajolu2rh	278	44	A	a	DT
cord-322166-ajolu2rh	278	45	virus	virus	NN
cord-322166-ajolu2rh	278	46	(	(	-LRB-
cord-322166-ajolu2rh	278	47	H5N1	H5N1	NNP
cord-322166-ajolu2rh	278	48	)	)	-RRB-
cord-322166-ajolu2rh	278	49	Evolution	evolution	NN
cord-322166-ajolu2rh	278	50	and	and	CC
cord-322166-ajolu2rh	278	51	ecology	ecology	NN
cord-322166-ajolu2rh	278	52	of	of	IN
cord-322166-ajolu2rh	278	53	influenza	influenza	NN
cord-322166-ajolu2rh	278	54	A	a	DT
cord-322166-ajolu2rh	278	55	viruses	virus	NNS
cord-322166-ajolu2rh	279	1	A	a	DT
cord-322166-ajolu2rh	279	2	complicated	complicated	JJ
cord-322166-ajolu2rh	279	3	message	message	NN
cord-322166-ajolu2rh	279	4	:	:	:
cord-322166-ajolu2rh	279	5	Identification	identification	NN
cord-322166-ajolu2rh	279	6	of	of	IN
cord-322166-ajolu2rh	279	7	a	a	DT
cord-322166-ajolu2rh	279	8	novel	novel	NN
cord-322166-ajolu2rh	279	9	PB1-related	pb1-relate	VBN
cord-322166-ajolu2rh	279	10	protein	protein	NN
cord-322166-ajolu2rh	279	11	translated	translate	VBN
cord-322166-ajolu2rh	279	12	from	from	IN
cord-322166-ajolu2rh	279	13	influenza	influenza	NN
cord-322166-ajolu2rh	279	14	A	a	DT
cord-322166-ajolu2rh	279	15	virus	virus	NN
cord-322166-ajolu2rh	279	16	segment	segment	NN
cord-322166-ajolu2rh	279	17	2	2	CD
cord-322166-ajolu2rh	279	18	mRNA	mRNA	NNP
cord-322166-ajolu2rh	279	19	Writing	Writing	NNP
cord-322166-ajolu2rh	279	20	Committee	Committee	NNP
cord-322166-ajolu2rh	279	21	of	of	IN
cord-322166-ajolu2rh	279	22	the	the	DT
cord-322166-ajolu2rh	279	23	Second	Second	NNP
cord-322166-ajolu2rh	279	24	World	World	NNP
cord-322166-ajolu2rh	279	25	Health	Health	NNP
cord-322166-ajolu2rh	279	26	Organization	Organization	NNP
cord-322166-ajolu2rh	279	27	Consultation	Consultation	NNP
cord-322166-ajolu2rh	279	28	on	on	IN
cord-322166-ajolu2rh	279	29	Clinical	clinical	JJ
cord-322166-ajolu2rh	279	30	Aspects	aspect	NNS
cord-322166-ajolu2rh	279	31	of	of	IN
cord-322166-ajolu2rh	279	32	Human	human	JJ
cord-322166-ajolu2rh	279	33	Infection	Infection	NNP
cord-322166-ajolu2rh	279	34	with	with	IN
cord-322166-ajolu2rh	279	35	Avian	Avian	NNP
cord-322166-ajolu2rh	279	36	Influenza	Influenza	NNP
cord-322166-ajolu2rh	279	37	A	A	NNP
cord-322166-ajolu2rh	279	38	(	(	-LRB-
cord-322166-ajolu2rh	279	39	H5N1	H5N1	NNP
cord-322166-ajolu2rh	279	40	)	)	-RRB-
cord-322166-ajolu2rh	279	41	V.	V.	NNP
cord-322166-ajolu2rh	279	42	2008	2008	CD
cord-322166-ajolu2rh	279	43	.	.	.
cord-322166-ajolu2rh	280	1	Update	update	NN
cord-322166-ajolu2rh	280	2	on	on	IN
cord-322166-ajolu2rh	280	3	avian	avian	JJ
cord-322166-ajolu2rh	280	4	influenza	influenza	NN
cord-322166-ajolu2rh	280	5	A	a	NN
cord-322166-ajolu2rh	281	1	(	(	-LRB-
cord-322166-ajolu2rh	281	2	H5N1	H5N1	NNP
cord-322166-ajolu2rh	281	3	)	)	-RRB-
cord-322166-ajolu2rh	281	4	virus	virus	NN
cord-322166-ajolu2rh	281	5	infection	infection	NN
cord-322166-ajolu2rh	281	6	in	in	IN
cord-322166-ajolu2rh	281	7	humans	human	NNS
cord-322166-ajolu2rh	282	1	Viral	viral	JJ
cord-322166-ajolu2rh	282	2	replication	replication	NN
cord-322166-ajolu2rh	282	3	and	and	CC
cord-322166-ajolu2rh	282	4	innate	innate	JJ
cord-322166-ajolu2rh	282	5	host	host	NN
cord-322166-ajolu2rh	282	6	responses	response	NNS
cord-322166-ajolu2rh	282	7	in	in	IN
cord-322166-ajolu2rh	282	8	primary	primary	JJ
cord-322166-ajolu2rh	282	9	human	human	JJ
cord-322166-ajolu2rh	282	10	alveolar	alveolar	NN
cord-322166-ajolu2rh	282	11	epithelial	epithelial	JJ
cord-322166-ajolu2rh	282	12	cells	cell	NNS
cord-322166-ajolu2rh	282	13	and	and	CC
cord-322166-ajolu2rh	282	14	alveolar	alveolar	NN
cord-322166-ajolu2rh	282	15	macrophages	macrophage	NNS
cord-322166-ajolu2rh	282	16	infected	infect	VBN
cord-322166-ajolu2rh	282	17	with	with	IN
cord-322166-ajolu2rh	282	18	influenza	influenza	NN
cord-322166-ajolu2rh	282	19	H5N1	H5N1	NNP
cord-322166-ajolu2rh	282	20	and	and	CC
cord-322166-ajolu2rh	282	21	H1N1	H1N1	NNP
cord-322166-ajolu2rh	282	22	viruses	viruse	VBZ
cord-322166-ajolu2rh	282	23	Clinical	clinical	JJ
cord-322166-ajolu2rh	282	24	features	feature	NNS
cord-322166-ajolu2rh	282	25	and	and	CC
cord-322166-ajolu2rh	282	26	rapid	rapid	JJ
cord-322166-ajolu2rh	282	27	viral	viral	JJ
cord-322166-ajolu2rh	282	28	diagnosis	diagnosis	NN
cord-322166-ajolu2rh	282	29	of	of	IN
cord-322166-ajolu2rh	282	30	human	human	JJ
cord-322166-ajolu2rh	282	31	disease	disease	NN
cord-322166-ajolu2rh	282	32	associated	associate	VBN
cord-322166-ajolu2rh	282	33	with	with	IN
cord-322166-ajolu2rh	282	34	avian	avian	JJ
cord-322166-ajolu2rh	282	35	influenza	influenza	NN
cord-322166-ajolu2rh	282	36	A	a	DT
cord-322166-ajolu2rh	282	37	H5N1	H5N1	NNP
cord-322166-ajolu2rh	282	38	virus	virus	NN
cord-322166-ajolu2rh	282	39	Influenza	Influenza	NNP
cord-322166-ajolu2rh	282	40	A	a	DT
cord-322166-ajolu2rh	282	41	virus	virus	NN
cord-322166-ajolu2rh	282	42	PB1-F2	PB1-F2	NNP
cord-322166-ajolu2rh	282	43	protein	protein	NN
cord-322166-ajolu2rh	282	44	contributes	contribute	VBZ
cord-322166-ajolu2rh	282	45	to	to	IN
cord-322166-ajolu2rh	282	46	viral	viral	JJ
cord-322166-ajolu2rh	282	47	pathogenesis	pathogenesis	NN
cord-322166-ajolu2rh	282	48	in	in	IN
cord-322166-ajolu2rh	282	49	mice	mouse	NNS
cord-322166-ajolu2rh	282	50	Influenza	Influenza	NNP
cord-322166-ajolu2rh	282	51	virus	virus	NN
cord-322166-ajolu2rh	283	1	PB1-F2	pb1-f2	JJ
cord-322166-ajolu2rh	283	2	protein	protein	NN
cord-322166-ajolu2rh	283	3	induces	induce	VBZ
cord-322166-ajolu2rh	283	4	cell	cell	NN
cord-322166-ajolu2rh	283	5	death	death	NN
cord-322166-ajolu2rh	283	6	through	through	IN
cord-322166-ajolu2rh	283	7	mitochondrial	mitochondrial	JJ
cord-322166-ajolu2rh	283	8	ANT3	ANT3	NNP
cord-322166-ajolu2rh	283	9	and	and	CC
cord-322166-ajolu2rh	283	10	VDAC1	vdac1	NN
cord-322166-ajolu2rh	283	11	Highly	highly	RB
cord-322166-ajolu2rh	283	12	pathogenic	pathogenic	JJ
cord-322166-ajolu2rh	283	13	avian	avian	JJ
cord-322166-ajolu2rh	283	14	influenza	influenza	NN
cord-322166-ajolu2rh	283	15	H5N1	H5N1	NNP
cord-322166-ajolu2rh	283	16	viruses	virus	NNS
cord-322166-ajolu2rh	283	17	elicit	elicit	VBP
cord-322166-ajolu2rh	283	18	an	an	DT
cord-322166-ajolu2rh	283	19	attenuated	attenuated	JJ
cord-322166-ajolu2rh	283	20	type	type	NN
cord-322166-ajolu2rh	283	21	i	i	PRP
cord-322166-ajolu2rh	283	22	interferon	interferon	VBD
cord-322166-ajolu2rh	283	23	response	response	NN
cord-322166-ajolu2rh	283	24	in	in	IN
cord-322166-ajolu2rh	283	25	polarized	polarized	JJ
cord-322166-ajolu2rh	283	26	human	human	JJ
cord-322166-ajolu2rh	283	27	bronchial	bronchial	JJ
cord-322166-ajolu2rh	283	28	epithelial	epithelial	JJ
cord-322166-ajolu2rh	283	29	cells	cell	NNS
cord-322166-ajolu2rh	283	30	Delayed	delay	VBN
cord-322166-ajolu2rh	283	31	antiviral	antiviral	JJ
cord-322166-ajolu2rh	283	32	plus	plus	CC
cord-322166-ajolu2rh	283	33	immunomodulator	immunomodulator	NNP
cord-322166-ajolu2rh	283	34	treatment	treatment	NN
cord-322166-ajolu2rh	283	35	still	still	RB
cord-322166-ajolu2rh	283	36	reduces	reduce	VBZ
cord-322166-ajolu2rh	283	37	mortality	mortality	NN
cord-322166-ajolu2rh	283	38	in	in	IN
cord-322166-ajolu2rh	283	39	mice	mouse	NNS
cord-322166-ajolu2rh	283	40	infected	infect	VBN
cord-322166-ajolu2rh	283	41	by	by	IN
cord-322166-ajolu2rh	283	42	high	high	JJ
cord-322166-ajolu2rh	283	43	inoculum	inoculum	NN
cord-322166-ajolu2rh	283	44	of	of	IN
cord-322166-ajolu2rh	283	45	influenza	influenza	NN
cord-322166-ajolu2rh	283	46	A	A	NNP
cord-322166-ajolu2rh	283	47	/	/	SYM
cord-322166-ajolu2rh	283	48	H5N1	H5N1	NNP
cord-322166-ajolu2rh	283	49	virus	virus	NN
cord-322166-ajolu2rh	284	1	A	a	DT
cord-322166-ajolu2rh	284	2	naturally	naturally	RB
cord-322166-ajolu2rh	284	3	occurring	occur	VBG
cord-322166-ajolu2rh	284	4	deletion	deletion	NN
cord-322166-ajolu2rh	284	5	in	in	IN
cord-322166-ajolu2rh	284	6	its	-PRON-	PRP$
cord-322166-ajolu2rh	284	7	NS	NS	NNP
cord-322166-ajolu2rh	284	8	gene	gene	NN
cord-322166-ajolu2rh	284	9	contributes	contribute	VBZ
cord-322166-ajolu2rh	284	10	to	to	IN
cord-322166-ajolu2rh	284	11	the	the	DT
cord-322166-ajolu2rh	284	12	attenuation	attenuation	NN
cord-322166-ajolu2rh	284	13	of	of	IN
cord-322166-ajolu2rh	284	14	an	an	DT
cord-322166-ajolu2rh	284	15	H5N1	H5N1	NNP
cord-322166-ajolu2rh	284	16	swine	swine	NN
cord-322166-ajolu2rh	284	17	influenza	influenza	NN
cord-322166-ajolu2rh	284	18	virus	virus	NN
cord-322166-ajolu2rh	284	19	in	in	IN
cord-322166-ajolu2rh	284	20	chickens	chicken	NNS