id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-254950-y6kayxie	Morse, Stephen S.	Mouse thymic virus (MTLV; Murid Herpesvirus 3) infection in athymic nude mice: Evidence for a T lymphocyte requirement	1988-03-31		.txt	text/plain	2123	99	51	Abstract Mouse thymic virus (MTLV; murid herpesvirus 3) is a lymphotropic herpesvirus that cytolytically infects developing T lineage lymphocytes in the thymus of neonatal mice. In order to determine whether T lineage lymphocytes are required for infection, young adult athymic nude (nulnu) mice and euthymic littermates were infected with MTLV and tested for virus shedding. To determine whether MTLV infection requires thymus-derived lymphocytes, 4-week-old female ICR Swiss athymic nude (nulnu) and euthymic (+lnu) littermate controls (four each; Memorial Sloan-Kettering Cancer Center nude mouse breeding colony) were inoculated intraperitoneally with either 40 or 200 IDS0 of MTLV and virus shedding was tested by mouth swabs beginning 6 days after infection. litters available did not allow every negative sample to be tested, additional litters of normal newborn mice were inoculated with fresh homogenates (1 O-20%, w/v) of randomly selected negative thymuses and salivary glands, representing various test dates up to Day 48, from 14 assay litters that had received swab fluids from nude mice.	./cache/cord-254950-y6kayxie.txt	./txt/cord-254950-y6kayxie.txt