id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265156-u1re7983	de Wilde, Adriaan H.	Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture	2017-12-15		.txt	text/plain	6306	327	53	Here, we investigated the CypA dependence of three distantly related nidoviruses that can all replicate in Huh7 cells: the arterivirus equine arteritis virus (EAV), the alphacoronavirus human coronavirus 229E (HCoV-229E), and the betacoronavirus Middle East respiratory syndrome coronavirus (MERS-CoV). The replication in cell culture of the arterivirus equine arteritis virus (EAV; de Wilde et al., 2013a) and the alphacoronaviruses feline coronavirus (FCoV; Tanaka et al., 2017) , human coronavirus (HCoV) NL63 (Carbajo-Lozoya et al., 2014), and HCoV-229E (von Brunn et al., 2015) was reported to be affected by CypA knockdown (KD) or knockout (KO), although the level of CypA dependence of these viruses, which was not compared directly, appeared to be quite different. Using different cell lines, the replication of two of these viruses, the arterivirus EAV (de Wilde et al., 2013a) and the alphacoronavirus HCoV-229E , was previously concluded to depend on CypA.	./cache/cord-265156-u1re7983.txt	./txt/cord-265156-u1re7983.txt