id author title date pages extension mime words sentences flesch summary cache txt cord-279813-mrei5kih Temeeyasen, G. Differential gene modulation of pattern-recognition receptor TLR and RIG-I-like and downstream mediators on intestinal mucosa of pigs infected with PEDV non S-INDEL and PEDV S-INDEL strains 2017-12-14 .txt text/plain 6657 337 49 authors: Temeeyasen, G.; Sinha, A.; Gimenez-Lirola, L.G.; Zhang, J.Q.; PiƱeyro, P.E. title: Differential gene modulation of pattern-recognition receptor TLR and RIG-I-like and downstream mediators on intestinal mucosa of pigs infected with PEDV non S-INDEL and PEDV S-INDEL strains The aim of this study was to investigate the differential gene modulation of pattern recognition TLR and RIG-I-like receptors and downstream mediators on the intestinal mucosa of neonatal pigs infected with PEDV non-S-INDEL and PEDV S-INDEL strains. We evaluated whether the differential modulatory effect observed in PRRs and downstream mediators in response to infection with the PEDV S-INDEL versus the non-S-INDEL strain was also translated into a differential modulation in the expression of gene coding for pro-inflammatory cytokines and type I interferons. Changes in TNF receptor associated factor (TRAF) 6 and interferon regulatory factor 7 (IRF7) genes mRNA expression induced by porcine epidemic diarrhea virus (PEDV) non S-INDEL and PEDV S-INDEL strains in intestinal mucosa (A-B). ./cache/cord-279813-mrei5kih.txt ./txt/cord-279813-mrei5kih.txt