id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280287-t7uozjml	Favier, Anne-Laure	Unique physicochemical properties of human enteric Ad41 responsible for its survival and replication in the gastrointestinal tract	2004-04-25		.txt	text/plain	6968	382	52	We show that Ad41 infectivity is not diminished by acid exposure, a condition limiting the infectivity of the respiratory Ad. This feature can be attributed to a large extent to the global basic charge of enteric Ad virions and to the stability of Ad41 fiber, a viral protein mediating virus attachment. During cell attachment, the distal C-terminal globular head domain of the fiber protein interacts with the primary receptor, which for some human Ad serotypes is the coxsackievirus and adenovirus receptor (CAR) (Bergelson et al., 1997; Roelvink et al., 1998) . In the first attempt to understand the survival mechanism of the human enteric Ad41 under acid conditions of the stomach, we compared the predicted pI values of external structural proteins of different Ad serotypes (Table 1) .	./cache/cord-280287-t7uozjml.txt	./txt/cord-280287-t7uozjml.txt