id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-289045-vft163v0	Thackray, Larissa B.	Substitutions of conserved amino acids in the receptor-binding domain of the spike glycoprotein affect utilization of murine CEACAM1a by the murine coronavirus MHV-A59	2005-03-30		.txt	text/plain	7779	345	56	Cell lines from host species that are normally resistant to MHV, porcine coronavirus [transmissible gastroenteritis virus (TGEV)] or human coronavirus strain 229E (HCoV-229E) are rendered susceptible to infection by transfection with cDNA encoding the specific coronavirus receptors mCEACAM1a, porcine aminopeptidase N (pAPN) (Delmas et al., 1992; Dveksler et al., 1991; Yeager et al., 1992) . Since some of the aa substitutions in the RBD of S were chosen to reflect residues found in S330 of related rat, bovine or human coronaviruses in group II (Fig. 1A) , we examined the ability of the SA59 B, S33R A, S33G C, T62S A, T62A A, L65H C, L65A C, L79M/T82M A, L79A/ T82A B, Y162F A, K183R A and K183G A viruses to infect non-murine cells lines that are normally resistant to MHV-A59 infection.	./cache/cord-289045-vft163v0.txt	./txt/cord-289045-vft163v0.txt