id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313906-fh85fzq9	Maruyama, Junki	Characterization of the glycoproteins of bat-derived influenza viruses	2016-01-15		.txt	text/plain	4241	232	51	We found that VSVs pseudotyped with BatIV HAs and NAs efficiently infected particular bat cell lines but not those derived from primates, and that proteolytic cleavage with a trypsin-like protease was necessary for HA-mediated virus entry. Treatment of the susceptible bat cells with some enzymes and inhibitors revealed that BatIV HAs might recognize some cellular glycoproteins as receptors rather than the sialic acids used for the other known influenza viruses. To obtain information on the biological characteristics of cellular receptors for BatIVs, IndFSPT1 cells were pretreated with tunicamycin, pronase, or neuraminidase (i.e., an N-linked glycosylation inhibitor, mixture of proteases, and sialidase, respectively), and then infected with pseudotyped VSVs (Fig. 4B-D) . IndFSPT1 should also have such molecules since it showed the highest susceptibility to BatIV HA-pseudotyped VSVs. It was noted that VSVΔG*-H17N10 and -H18N11 also infected MDCK cells, although less efficiently than these bat cell lines.	./cache/cord-313906-fh85fzq9.txt	./txt/cord-313906-fh85fzq9.txt