id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344515-e0g911le	Voss, Kelsey	Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells	2014-11-30		.txt	text/plain	9184	499	54	title: Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells Our previous studies have indicated that host kinases including IKK-β and GSK-3β were modulated in VEEV-infected cells and that inhibition of these kinases with small molecule inhibitors resulted in decreased viral multiplication (Amaya et al., 2014; Kehn-Hall et al., 2012) . Cumulatively, the data included in Fig. 1 suggest that infection of U87MGs with the attenuated TC-83 strain of VEEV results in an activation of the ERK signaling cascade and phosphorylation of ERK1/2 at early time points after infection. Therefore, to confirm that Ag-126 treatment indeed resulted in decreased phosphorylation of ERK1/2 in U87MG cells, we investigated the intracellular p-ERK1/2 localization during VEEV infection in the presence or absence of Ag-126 at different time points using confocal microscopy as described previously (Amaya et al., 2014) .	./cache/cord-344515-e0g911le.txt	./txt/cord-344515-e0g911le.txt