id	sid	tid	token	lemma	pos
cord-273487-nfgjz6f9	1	1	key	key	JJ
cord-273487-nfgjz6f9	1	2	:	:	:
cord-273487-nfgjz6f9	1	3	cord-273487-nfgjz6f9	cord-273487-nfgjz6f9	NN
cord-273487-nfgjz6f9	1	4	authors	author	NNS
cord-273487-nfgjz6f9	1	5	:	:	:
cord-273487-nfgjz6f9	1	6	Xu	Xu	NNP
cord-273487-nfgjz6f9	1	7	,	,	,
cord-273487-nfgjz6f9	1	8	Zaikun	Zaikun	NNP
cord-273487-nfgjz6f9	1	9	;	;	:
cord-273487-nfgjz6f9	1	10	Hobman	Hobman	NNP
cord-273487-nfgjz6f9	1	11	,	,	,
cord-273487-nfgjz6f9	1	12	Tom	Tom	NNP
cord-273487-nfgjz6f9	1	13	C.	C.	NNP
cord-273487-nfgjz6f9	1	14	title	title	NN
cord-273487-nfgjz6f9	1	15	:	:	:
cord-273487-nfgjz6f9	2	1	The	the	DT
cord-273487-nfgjz6f9	2	2	helicase	helicase	NN
cord-273487-nfgjz6f9	2	3	activity	activity	NN
cord-273487-nfgjz6f9	2	4	of	of	IN
cord-273487-nfgjz6f9	2	5	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	2	6	is	be	VBZ
cord-273487-nfgjz6f9	2	7	required	require	VBN
cord-273487-nfgjz6f9	2	8	for	for	IN
cord-273487-nfgjz6f9	2	9	its	-PRON-	PRP$
cord-273487-nfgjz6f9	2	10	role	role	NN
cord-273487-nfgjz6f9	2	11	in	in	IN
cord-273487-nfgjz6f9	2	12	assembly	assembly	NN
cord-273487-nfgjz6f9	2	13	of	of	IN
cord-273487-nfgjz6f9	2	14	infectious	infectious	JJ
cord-273487-nfgjz6f9	2	15	West	West	NNP
cord-273487-nfgjz6f9	2	16	Nile	Nile	NNP
cord-273487-nfgjz6f9	2	17	virus	virus	NN
cord-273487-nfgjz6f9	2	18	particles	particle	NNS
cord-273487-nfgjz6f9	2	19	date	date	NN
cord-273487-nfgjz6f9	2	20	:	:	:
cord-273487-nfgjz6f9	2	21	2012	2012	CD
cord-273487-nfgjz6f9	2	22	-	-	SYM
cord-273487-nfgjz6f9	2	23	11	11	CD
cord-273487-nfgjz6f9	2	24	-	-	SYM
cord-273487-nfgjz6f9	2	25	10	10	CD
cord-273487-nfgjz6f9	2	26	journal	journal	NN
cord-273487-nfgjz6f9	2	27	:	:	:
cord-273487-nfgjz6f9	3	1	Virology	virology	NN
cord-273487-nfgjz6f9	3	2	DOI	DOI	NNP
cord-273487-nfgjz6f9	3	3	:	:	:
cord-273487-nfgjz6f9	3	4	10.1016	10.1016	CD
cord-273487-nfgjz6f9	3	5	/	/	SYM
cord-273487-nfgjz6f9	3	6	j.virol.2012.08.011	j.virol.2012.08.011	NNP
cord-273487-nfgjz6f9	3	7	sha	sha	NNP
cord-273487-nfgjz6f9	3	8	:	:	:
cord-273487-nfgjz6f9	4	1	380afa473441d4d993bcd07fe9b73452dc026b57	380afa473441d4d993bcd07fe9b73452dc026b57	LS
cord-273487-nfgjz6f9	4	2	doc_id	doc_id	CD
cord-273487-nfgjz6f9	4	3	:	:	:
cord-273487-nfgjz6f9	4	4	273487	273487	CD
cord-273487-nfgjz6f9	4	5	cord_uid	cord_uid	NNS
cord-273487-nfgjz6f9	4	6	:	:	:
cord-273487-nfgjz6f9	5	1	nfgjz6f9	nfgjz6f9	JJ
cord-273487-nfgjz6f9	6	1	Although	although	IN
cord-273487-nfgjz6f9	6	2	flaviviruses	flavivirus	NNS
cord-273487-nfgjz6f9	6	3	encode	encode	VBP
cord-273487-nfgjz6f9	6	4	their	-PRON-	PRP$
cord-273487-nfgjz6f9	6	5	own	own	JJ
cord-273487-nfgjz6f9	6	6	helicases	helicase	NNS
cord-273487-nfgjz6f9	6	7	,	,	,
cord-273487-nfgjz6f9	6	8	evidence	evidence	NN
cord-273487-nfgjz6f9	6	9	suggests	suggest	VBZ
cord-273487-nfgjz6f9	6	10	that	that	IN
cord-273487-nfgjz6f9	6	11	cellular	cellular	JJ
cord-273487-nfgjz6f9	6	12	helicases	helicase	NNS
cord-273487-nfgjz6f9	6	13	are	be	VBP
cord-273487-nfgjz6f9	6	14	also	also	RB
cord-273487-nfgjz6f9	6	15	required	require	VBN
cord-273487-nfgjz6f9	6	16	for	for	IN
cord-273487-nfgjz6f9	6	17	replication	replication	NN
cord-273487-nfgjz6f9	6	18	and/or	and/or	CC
cord-273487-nfgjz6f9	6	19	assembly	assembly	NN
cord-273487-nfgjz6f9	6	20	of	of	IN
cord-273487-nfgjz6f9	6	21	these	these	DT
cord-273487-nfgjz6f9	6	22	viruses	virus	NNS
cord-273487-nfgjz6f9	6	23	.	.	.
cord-273487-nfgjz6f9	7	1	By	by	IN
cord-273487-nfgjz6f9	7	2	and	and	CC
cord-273487-nfgjz6f9	7	3	large	large	JJ
cord-273487-nfgjz6f9	7	4	,	,	,
cord-273487-nfgjz6f9	7	5	the	the	DT
cord-273487-nfgjz6f9	7	6	mechanisms	mechanism	NNS
cord-273487-nfgjz6f9	7	7	of	of	IN
cord-273487-nfgjz6f9	7	8	action	action	NN
cord-273487-nfgjz6f9	7	9	for	for	IN
cord-273487-nfgjz6f9	7	10	viral	viral	JJ
cord-273487-nfgjz6f9	7	11	and	and	CC
cord-273487-nfgjz6f9	7	12	cellular	cellular	JJ
cord-273487-nfgjz6f9	7	13	helicases	helicase	NNS
cord-273487-nfgjz6f9	7	14	are	be	VBP
cord-273487-nfgjz6f9	7	15	not	not	RB
cord-273487-nfgjz6f9	7	16	known	know	VBN
cord-273487-nfgjz6f9	7	17	.	.	.
cord-273487-nfgjz6f9	8	1	Moreover	moreover	RB
cord-273487-nfgjz6f9	8	2	,	,	,
cord-273487-nfgjz6f9	8	3	in	in	IN
cord-273487-nfgjz6f9	8	4	some	some	DT
cord-273487-nfgjz6f9	8	5	cases	case	NNS
cord-273487-nfgjz6f9	8	6	,	,	,
cord-273487-nfgjz6f9	8	7	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	8	8	activity	activity	NN
cord-273487-nfgjz6f9	8	9	is	be	VBZ
cord-273487-nfgjz6f9	8	10	not	not	RB
cord-273487-nfgjz6f9	8	11	even	even	RB
cord-273487-nfgjz6f9	8	12	required	require	VBN
cord-273487-nfgjz6f9	8	13	for	for	IN
cord-273487-nfgjz6f9	8	14	their	-PRON-	PRP$
cord-273487-nfgjz6f9	8	15	roles	role	NNS
cord-273487-nfgjz6f9	8	16	in	in	IN
cord-273487-nfgjz6f9	8	17	virus	virus	NN
cord-273487-nfgjz6f9	8	18	biology	biology	NN
cord-273487-nfgjz6f9	8	19	.	.	.
cord-273487-nfgjz6f9	9	1	Recently	recently	RB
cord-273487-nfgjz6f9	9	2	,	,	,
cord-273487-nfgjz6f9	9	3	we	-PRON-	PRP
cord-273487-nfgjz6f9	9	4	showed	show	VBD
cord-273487-nfgjz6f9	9	5	that	that	IN
cord-273487-nfgjz6f9	9	6	expression	expression	NN
cord-273487-nfgjz6f9	9	7	of	of	IN
cord-273487-nfgjz6f9	9	8	the	the	DT
cord-273487-nfgjz6f9	9	9	host	host	NN
cord-273487-nfgjz6f9	9	10	nucleolar	nucleolar	NN
cord-273487-nfgjz6f9	9	11	helicase	helicase	NNP
cord-273487-nfgjz6f9	9	12	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	9	13	is	be	VBZ
cord-273487-nfgjz6f9	9	14	important	important	JJ
cord-273487-nfgjz6f9	9	15	for	for	IN
cord-273487-nfgjz6f9	9	16	infectivity	infectivity	NN
cord-273487-nfgjz6f9	9	17	of	of	IN
cord-273487-nfgjz6f9	9	18	West	West	NNP
cord-273487-nfgjz6f9	9	19	Nile	Nile	NNP
cord-273487-nfgjz6f9	9	20	virus	virus	NN
cord-273487-nfgjz6f9	9	21	(	(	-LRB-
cord-273487-nfgjz6f9	9	22	WNV	WNV	NNP
cord-273487-nfgjz6f9	9	23	)	)	-RRB-
cord-273487-nfgjz6f9	9	24	particles	particle	NNS
cord-273487-nfgjz6f9	9	25	.	.	.
cord-273487-nfgjz6f9	10	1	In	in	IN
cord-273487-nfgjz6f9	10	2	the	the	DT
cord-273487-nfgjz6f9	10	3	present	present	JJ
cord-273487-nfgjz6f9	10	4	study	study	NN
cord-273487-nfgjz6f9	10	5	,	,	,
cord-273487-nfgjz6f9	10	6	we	-PRON-	PRP
cord-273487-nfgjz6f9	10	7	demonstrate	demonstrate	VBP
cord-273487-nfgjz6f9	10	8	that	that	IN
cord-273487-nfgjz6f9	10	9	the	the	DT
cord-273487-nfgjz6f9	10	10	helicase	helicase	NN
cord-273487-nfgjz6f9	10	11	activity	activity	NN
cord-273487-nfgjz6f9	10	12	of	of	IN
cord-273487-nfgjz6f9	10	13	this	this	DT
cord-273487-nfgjz6f9	10	14	enzyme	enzyme	NN
cord-273487-nfgjz6f9	10	15	is	be	VBZ
cord-273487-nfgjz6f9	10	16	essential	essential	JJ
cord-273487-nfgjz6f9	10	17	for	for	IN
cord-273487-nfgjz6f9	10	18	its	-PRON-	PRP$
cord-273487-nfgjz6f9	10	19	role	role	NN
cord-273487-nfgjz6f9	10	20	in	in	IN
cord-273487-nfgjz6f9	10	21	assembly	assembly	NN
cord-273487-nfgjz6f9	10	22	of	of	IN
cord-273487-nfgjz6f9	10	23	infectious	infectious	JJ
cord-273487-nfgjz6f9	10	24	WNV	WNV	NNP
cord-273487-nfgjz6f9	10	25	virions	virion	NNS
cord-273487-nfgjz6f9	10	26	.	.	.
cord-273487-nfgjz6f9	11	1	Over	over	IN
cord-273487-nfgjz6f9	11	2	-	-	HYPH
cord-273487-nfgjz6f9	11	3	expression	expression	NN
cord-273487-nfgjz6f9	11	4	of	of	IN
cord-273487-nfgjz6f9	11	5	the	the	DT
cord-273487-nfgjz6f9	11	6	capsid	capsid	RB
cord-273487-nfgjz6f9	11	7	-	-	HYPH
cord-273487-nfgjz6f9	11	8	binding	bind	VBG
cord-273487-nfgjz6f9	11	9	region	region	NN
cord-273487-nfgjz6f9	11	10	of	of	IN
cord-273487-nfgjz6f9	11	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	11	12	also	also	RB
cord-273487-nfgjz6f9	11	13	reduces	reduce	VBZ
cord-273487-nfgjz6f9	11	14	infectivity	infectivity	NN
cord-273487-nfgjz6f9	11	15	of	of	IN
cord-273487-nfgjz6f9	11	16	WNV	WNV	NNP
cord-273487-nfgjz6f9	11	17	suggesting	suggest	VBG
cord-273487-nfgjz6f9	11	18	that	that	IN
cord-273487-nfgjz6f9	11	19	interaction	interaction	NN
cord-273487-nfgjz6f9	11	20	of	of	IN
cord-273487-nfgjz6f9	11	21	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	11	22	and	and	CC
cord-273487-nfgjz6f9	11	23	capsid	capsid	NN
cord-273487-nfgjz6f9	11	24	protein	protein	NN
cord-273487-nfgjz6f9	11	25	is	be	VBZ
cord-273487-nfgjz6f9	11	26	an	an	DT
cord-273487-nfgjz6f9	11	27	important	important	JJ
cord-273487-nfgjz6f9	11	28	step	step	NN
cord-273487-nfgjz6f9	11	29	in	in	IN
cord-273487-nfgjz6f9	11	30	the	the	DT
cord-273487-nfgjz6f9	11	31	virion	virion	NN
cord-273487-nfgjz6f9	11	32	assembly	assembly	NN
cord-273487-nfgjz6f9	11	33	pathway	pathway	NN
cord-273487-nfgjz6f9	11	34	.	.	.
cord-273487-nfgjz6f9	12	1	To	to	IN
cord-273487-nfgjz6f9	12	2	our	-PRON-	PRP$
cord-273487-nfgjz6f9	12	3	knowledge	knowledge	NN
cord-273487-nfgjz6f9	12	4	,	,	,
cord-273487-nfgjz6f9	12	5	this	this	DT
cord-273487-nfgjz6f9	12	6	is	be	VBZ
cord-273487-nfgjz6f9	12	7	the	the	DT
cord-273487-nfgjz6f9	12	8	first	first	JJ
cord-273487-nfgjz6f9	12	9	study	study	NN
cord-273487-nfgjz6f9	12	10	showing	show	VBG
cord-273487-nfgjz6f9	12	11	that	that	IN
cord-273487-nfgjz6f9	12	12	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	12	13	activity	activity	NN
cord-273487-nfgjz6f9	12	14	of	of	IN
cord-273487-nfgjz6f9	12	15	a	a	DT
cord-273487-nfgjz6f9	12	16	cellular	cellular	JJ
cord-273487-nfgjz6f9	12	17	helicase	helicase	NN
cord-273487-nfgjz6f9	12	18	is	be	VBZ
cord-273487-nfgjz6f9	12	19	critical	critical	JJ
cord-273487-nfgjz6f9	12	20	for	for	IN
cord-273487-nfgjz6f9	12	21	infectivity	infectivity	NN
cord-273487-nfgjz6f9	12	22	of	of	IN
cord-273487-nfgjz6f9	12	23	flaviviruses	flavivirus	NNS
cord-273487-nfgjz6f9	12	24	.	.	.
cord-273487-nfgjz6f9	13	1	West	West	NNP
cord-273487-nfgjz6f9	13	2	Nile	Nile	NNP
cord-273487-nfgjz6f9	13	3	virus	virus	NN
cord-273487-nfgjz6f9	13	4	(	(	-LRB-
cord-273487-nfgjz6f9	13	5	WNV	WNV	NNP
cord-273487-nfgjz6f9	13	6	)	)	-RRB-
cord-273487-nfgjz6f9	13	7	is	be	VBZ
cord-273487-nfgjz6f9	13	8	an	an	DT
cord-273487-nfgjz6f9	13	9	important	important	JJ
cord-273487-nfgjz6f9	13	10	human	human	JJ
cord-273487-nfgjz6f9	13	11	pathogen	pathogen	NN
cord-273487-nfgjz6f9	13	12	that	that	WDT
cord-273487-nfgjz6f9	13	13	can	can	MD
cord-273487-nfgjz6f9	13	14	cause	cause	VB
cord-273487-nfgjz6f9	13	15	severe	severe	JJ
cord-273487-nfgjz6f9	13	16	neurological	neurological	JJ
cord-273487-nfgjz6f9	13	17	disease	disease	NN
cord-273487-nfgjz6f9	13	18	(	(	-LRB-
cord-273487-nfgjz6f9	13	19	reviewed	review	VBN
cord-273487-nfgjz6f9	13	20	in	in	IN
cord-273487-nfgjz6f9	13	21	Brinton	Brinton	NNP
cord-273487-nfgjz6f9	13	22	,	,	,
cord-273487-nfgjz6f9	13	23	2002	2002	CD
cord-273487-nfgjz6f9	13	24	)	)	-RRB-
cord-273487-nfgjz6f9	13	25	.	.	.
cord-273487-nfgjz6f9	14	1	It	-PRON-	PRP
cord-273487-nfgjz6f9	14	2	is	be	VBZ
cord-273487-nfgjz6f9	14	3	wide	wide	JJ
cord-273487-nfgjz6f9	14	4	spread	spread	VBN
cord-273487-nfgjz6f9	14	5	throughout	throughout	IN
cord-273487-nfgjz6f9	14	6	the	the	DT
cord-273487-nfgjz6f9	14	7	globe	globe	NN
cord-273487-nfgjz6f9	14	8	and	and	CC
cord-273487-nfgjz6f9	14	9	is	be	VBZ
cord-273487-nfgjz6f9	14	10	maintained	maintain	VBN
cord-273487-nfgjz6f9	14	11	in	in	IN
cord-273487-nfgjz6f9	14	12	an	an	DT
cord-273487-nfgjz6f9	14	13	enzootic	enzootic	JJ
cord-273487-nfgjz6f9	14	14	cycle	cycle	NN
cord-273487-nfgjz6f9	14	15	with	with	IN
cord-273487-nfgjz6f9	14	16	birds	bird	NNS
cord-273487-nfgjz6f9	14	17	serving	serve	VBG
cord-273487-nfgjz6f9	14	18	as	as	IN
cord-273487-nfgjz6f9	14	19	the	the	DT
cord-273487-nfgjz6f9	14	20	main	main	JJ
cord-273487-nfgjz6f9	14	21	reservoir	reservoir	NN
cord-273487-nfgjz6f9	14	22	.	.	.
cord-273487-nfgjz6f9	15	1	Similar	similar	JJ
cord-273487-nfgjz6f9	15	2	to	to	IN
cord-273487-nfgjz6f9	15	3	most	most	JJS
cord-273487-nfgjz6f9	15	4	other	other	JJ
cord-273487-nfgjz6f9	15	5	flaviviruses	flavivirus	NNS
cord-273487-nfgjz6f9	15	6	,	,	,
cord-273487-nfgjz6f9	15	7	mosquito	mosquito	NN
cord-273487-nfgjz6f9	15	8	-	-	HYPH
cord-273487-nfgjz6f9	15	9	borne	bear	VBN
cord-273487-nfgjz6f9	15	10	transmission	transmission	NN
cord-273487-nfgjz6f9	15	11	is	be	VBZ
cord-273487-nfgjz6f9	15	12	the	the	DT
cord-273487-nfgjz6f9	15	13	main	main	JJ
cord-273487-nfgjz6f9	15	14	mode	mode	NN
cord-273487-nfgjz6f9	15	15	of	of	IN
cord-273487-nfgjz6f9	15	16	human	human	JJ
cord-273487-nfgjz6f9	15	17	infection	infection	NN
cord-273487-nfgjz6f9	15	18	.	.	.
cord-273487-nfgjz6f9	16	1	Currently	currently	RB
cord-273487-nfgjz6f9	16	2	,	,	,
cord-273487-nfgjz6f9	16	3	there	there	EX
cord-273487-nfgjz6f9	16	4	are	be	VBP
cord-273487-nfgjz6f9	16	5	no	no	DT
cord-273487-nfgjz6f9	16	6	WNV	WNV	NNP
cord-273487-nfgjz6f9	16	7	-	-	HYPH
cord-273487-nfgjz6f9	16	8	specific	specific	JJ
cord-273487-nfgjz6f9	16	9	vaccines	vaccine	NNS
cord-273487-nfgjz6f9	16	10	or	or	CC
cord-273487-nfgjz6f9	16	11	therapies	therapy	NNS
cord-273487-nfgjz6f9	16	12	that	that	WDT
cord-273487-nfgjz6f9	16	13	are	be	VBP
cord-273487-nfgjz6f9	16	14	approved	approve	VBN
cord-273487-nfgjz6f9	16	15	for	for	IN
cord-273487-nfgjz6f9	16	16	use	use	NN
cord-273487-nfgjz6f9	16	17	in	in	IN
cord-273487-nfgjz6f9	16	18	humans	human	NNS
cord-273487-nfgjz6f9	16	19	.	.	.
cord-273487-nfgjz6f9	17	1	As	as	IN
cord-273487-nfgjz6f9	17	2	with	with	IN
cord-273487-nfgjz6f9	17	3	all	all	DT
cord-273487-nfgjz6f9	17	4	viruses	virus	NNS
cord-273487-nfgjz6f9	17	5	,	,	,
cord-273487-nfgjz6f9	17	6	WNV	WNV	NNP
cord-273487-nfgjz6f9	17	7	is	be	VBZ
cord-273487-nfgjz6f9	17	8	an	an	DT
cord-273487-nfgjz6f9	17	9	obligate	obligate	JJ
cord-273487-nfgjz6f9	17	10	intracellular	intracellular	JJ
cord-273487-nfgjz6f9	17	11	parasite	parasite	NN
cord-273487-nfgjz6f9	17	12	that	that	WDT
cord-273487-nfgjz6f9	17	13	is	be	VBZ
cord-273487-nfgjz6f9	17	14	completely	completely	RB
cord-273487-nfgjz6f9	17	15	dependent	dependent	JJ
cord-273487-nfgjz6f9	17	16	upon	upon	IN
cord-273487-nfgjz6f9	17	17	the	the	DT
cord-273487-nfgjz6f9	17	18	host	host	NN
cord-273487-nfgjz6f9	17	19	cell	cell	NN
cord-273487-nfgjz6f9	17	20	for	for	IN
cord-273487-nfgjz6f9	17	21	viral	viral	JJ
cord-273487-nfgjz6f9	17	22	entry	entry	NN
cord-273487-nfgjz6f9	17	23	,	,	,
cord-273487-nfgjz6f9	17	24	replication	replication	NN
cord-273487-nfgjz6f9	17	25	,	,	,
cord-273487-nfgjz6f9	17	26	assembly	assembly	NN
cord-273487-nfgjz6f9	17	27	and	and	CC
cord-273487-nfgjz6f9	17	28	egress	egress	NN
cord-273487-nfgjz6f9	17	29	.	.	.
cord-273487-nfgjz6f9	18	1	A	a	DT
cord-273487-nfgjz6f9	18	2	recent	recent	JJ
cord-273487-nfgjz6f9	18	3	study	study	NN
cord-273487-nfgjz6f9	18	4	revealed	reveal	VBD
cord-273487-nfgjz6f9	18	5	that	that	IN
cord-273487-nfgjz6f9	18	6	more	more	JJR
cord-273487-nfgjz6f9	18	7	than	than	IN
cord-273487-nfgjz6f9	18	8	300	300	CD
cord-273487-nfgjz6f9	18	9	human	human	JJ
cord-273487-nfgjz6f9	18	10	genes	gene	NNS
cord-273487-nfgjz6f9	18	11	are	be	VBP
cord-273487-nfgjz6f9	18	12	required	require	VBN
cord-273487-nfgjz6f9	18	13	for	for	IN
cord-273487-nfgjz6f9	18	14	replication	replication	NN
cord-273487-nfgjz6f9	18	15	of	of	IN
cord-273487-nfgjz6f9	18	16	WNV	WNV	NNP
cord-273487-nfgjz6f9	18	17	and	and	CC
cord-273487-nfgjz6f9	18	18	the	the	DT
cord-273487-nfgjz6f9	18	19	closely	closely	RB
cord-273487-nfgjz6f9	18	20	related	relate	VBN
cord-273487-nfgjz6f9	18	21	flavivirus	flavivirus	NNP
cord-273487-nfgjz6f9	18	22	,	,	,
cord-273487-nfgjz6f9	18	23	Dengue	Dengue	NNP
cord-273487-nfgjz6f9	18	24	virus	virus	NN
cord-273487-nfgjz6f9	18	25	(	(	-LRB-
cord-273487-nfgjz6f9	18	26	Krishnan	Krishnan	NNP
cord-273487-nfgjz6f9	18	27	et	et	NNP
cord-273487-nfgjz6f9	18	28	al	al	NNP
cord-273487-nfgjz6f9	18	29	.	.	NNP
cord-273487-nfgjz6f9	18	30	,	,	,
cord-273487-nfgjz6f9	18	31	2008	2008	CD
cord-273487-nfgjz6f9	18	32	)	)	-RRB-
cord-273487-nfgjz6f9	18	33	.	.	.
cord-273487-nfgjz6f9	19	1	In	in	IN
cord-273487-nfgjz6f9	19	2	addition	addition	NN
cord-273487-nfgjz6f9	19	3	to	to	IN
cord-273487-nfgjz6f9	19	4	replication	replication	NN
cord-273487-nfgjz6f9	19	5	,	,	,
cord-273487-nfgjz6f9	19	6	we	-PRON-	PRP
cord-273487-nfgjz6f9	19	7	anticipate	anticipate	VBP
cord-273487-nfgjz6f9	19	8	that	that	IN
cord-273487-nfgjz6f9	19	9	many	many	JJ
cord-273487-nfgjz6f9	19	10	other	other	JJ
cord-273487-nfgjz6f9	19	11	human	human	JJ
cord-273487-nfgjz6f9	19	12	genes	gene	NNS
cord-273487-nfgjz6f9	19	13	are	be	VBP
cord-273487-nfgjz6f9	19	14	needed	need	VBN
cord-273487-nfgjz6f9	19	15	for	for	IN
cord-273487-nfgjz6f9	19	16	assembly	assembly	NN
cord-273487-nfgjz6f9	19	17	and	and	CC
cord-273487-nfgjz6f9	19	18	secretion	secretion	NN
cord-273487-nfgjz6f9	19	19	of	of	IN
cord-273487-nfgjz6f9	19	20	nascent	nascent	JJ
cord-273487-nfgjz6f9	19	21	WNV	WNV	NNP
cord-273487-nfgjz6f9	19	22	virions	virion	NNS
cord-273487-nfgjz6f9	19	23	.	.	.
cord-273487-nfgjz6f9	20	1	Rather	rather	RB
cord-273487-nfgjz6f9	20	2	than	than	IN
cord-273487-nfgjz6f9	20	3	conducting	conduct	VBG
cord-273487-nfgjz6f9	20	4	genome	genome	NN
cord-273487-nfgjz6f9	20	5	-	-	HYPH
cord-273487-nfgjz6f9	20	6	wide	wide	JJ
cord-273487-nfgjz6f9	20	7	screens	screen	NNS
cord-273487-nfgjz6f9	20	8	to	to	TO
cord-273487-nfgjz6f9	20	9	identify	identify	VB
cord-273487-nfgjz6f9	20	10	host	host	NN
cord-273487-nfgjz6f9	20	11	factors	factor	NNS
cord-273487-nfgjz6f9	20	12	that	that	WDT
cord-273487-nfgjz6f9	20	13	are	be	VBP
cord-273487-nfgjz6f9	20	14	involved	involve	VBN
cord-273487-nfgjz6f9	20	15	in	in	IN
cord-273487-nfgjz6f9	20	16	WNV	WNV	NNP
cord-273487-nfgjz6f9	20	17	biology	biology	NN
cord-273487-nfgjz6f9	20	18	,	,	,
cord-273487-nfgjz6f9	20	19	we	-PRON-	PRP
cord-273487-nfgjz6f9	20	20	focused	focus	VBD
cord-273487-nfgjz6f9	20	21	on	on	IN
cord-273487-nfgjz6f9	20	22	cellular	cellular	JJ
cord-273487-nfgjz6f9	20	23	proteins	protein	NNS
cord-273487-nfgjz6f9	20	24	that	that	WDT
cord-273487-nfgjz6f9	20	25	interact	interact	VBP
cord-273487-nfgjz6f9	20	26	with	with	IN
cord-273487-nfgjz6f9	20	27	the	the	DT
cord-273487-nfgjz6f9	20	28	capsid	capsid	JJ
cord-273487-nfgjz6f9	20	29	protein	protein	NN
cord-273487-nfgjz6f9	20	30	.	.	.
cord-273487-nfgjz6f9	21	1	In	in	IN
cord-273487-nfgjz6f9	21	2	addition	addition	NN
cord-273487-nfgjz6f9	21	3	to	to	IN
cord-273487-nfgjz6f9	21	4	performing	perform	VBG
cord-273487-nfgjz6f9	21	5	a	a	DT
cord-273487-nfgjz6f9	21	6	critical	critical	JJ
cord-273487-nfgjz6f9	21	7	structural	structural	JJ
cord-273487-nfgjz6f9	21	8	role	role	NN
cord-273487-nfgjz6f9	21	9	in	in	IN
cord-273487-nfgjz6f9	21	10	virus	virus	NN
cord-273487-nfgjz6f9	21	11	assembly	assembly	NN
cord-273487-nfgjz6f9	21	12	,	,	,
cord-273487-nfgjz6f9	21	13	our	-PRON-	PRP$
cord-273487-nfgjz6f9	21	14	data	datum	NNS
cord-273487-nfgjz6f9	21	15	indicate	indicate	VBP
cord-273487-nfgjz6f9	21	16	that	that	IN
cord-273487-nfgjz6f9	21	17	interactions	interaction	NNS
cord-273487-nfgjz6f9	21	18	between	between	IN
cord-273487-nfgjz6f9	21	19	this	this	DT
cord-273487-nfgjz6f9	21	20	viral	viral	JJ
cord-273487-nfgjz6f9	21	21	protein	protein	NN
cord-273487-nfgjz6f9	21	22	and	and	CC
cord-273487-nfgjz6f9	21	23	the	the	DT
cord-273487-nfgjz6f9	21	24	milieu	milieu	NN
cord-273487-nfgjz6f9	21	25	of	of	IN
cord-273487-nfgjz6f9	21	26	host	host	NN
cord-273487-nfgjz6f9	21	27	proteins	protein	NNS
cord-273487-nfgjz6f9	21	28	may	may	MD
cord-273487-nfgjz6f9	21	29	contribute	contribute	VB
cord-273487-nfgjz6f9	21	30	to	to	IN
cord-273487-nfgjz6f9	21	31	pathogenesis	pathogenesis	NN
cord-273487-nfgjz6f9	21	32	van	van	NNP
cord-273487-nfgjz6f9	21	33	Marle	Marle	NNP
cord-273487-nfgjz6f9	21	34	et	et	NNP
cord-273487-nfgjz6f9	21	35	al	al	NNP
cord-273487-nfgjz6f9	21	36	.	.	NNP
cord-273487-nfgjz6f9	21	37	,	,	,
cord-273487-nfgjz6f9	21	38	2007	2007	CD
cord-273487-nfgjz6f9	21	39	)	)	-RRB-
cord-273487-nfgjz6f9	21	40	.	.	.
cord-273487-nfgjz6f9	22	1	As	as	RB
cord-273487-nfgjz6f9	22	2	well	well	RB
cord-273487-nfgjz6f9	22	3	as	as	IN
cord-273487-nfgjz6f9	22	4	potentially	potentially	RB
cord-273487-nfgjz6f9	22	5	functioning	function	VBG
cord-273487-nfgjz6f9	22	6	in	in	IN
cord-273487-nfgjz6f9	22	7	a	a	DT
cord-273487-nfgjz6f9	22	8	negative	negative	JJ
cord-273487-nfgjz6f9	22	9	capacity	capacity	NN
cord-273487-nfgjz6f9	22	10	at	at	IN
cord-273487-nfgjz6f9	22	11	the	the	DT
cord-273487-nfgjz6f9	22	12	virus	virus	NN
cord-273487-nfgjz6f9	22	13	-	-	HYPH
cord-273487-nfgjz6f9	22	14	host	host	NN
cord-273487-nfgjz6f9	22	15	interface	interface	NN
cord-273487-nfgjz6f9	22	16	,	,	,
cord-273487-nfgjz6f9	22	17	interaction	interaction	NN
cord-273487-nfgjz6f9	22	18	of	of	IN
cord-273487-nfgjz6f9	22	19	WNV	WNV	NNP
cord-273487-nfgjz6f9	22	20	capsid	capsid	NN
cord-273487-nfgjz6f9	22	21	with	with	IN
cord-273487-nfgjz6f9	22	22	host	host	NN
cord-273487-nfgjz6f9	22	23	proteins	protein	NNS
cord-273487-nfgjz6f9	22	24	may	may	MD
cord-273487-nfgjz6f9	22	25	be	be	VB
cord-273487-nfgjz6f9	22	26	required	require	VBN
cord-273487-nfgjz6f9	22	27	for	for	IN
cord-273487-nfgjz6f9	22	28	replication	replication	NN
cord-273487-nfgjz6f9	22	29	and/or	and/or	CC
cord-273487-nfgjz6f9	22	30	virus	virus	NN
cord-273487-nfgjz6f9	22	31	assembly	assembly	NN
cord-273487-nfgjz6f9	22	32	.	.	.
cord-273487-nfgjz6f9	23	1	With	with	IN
cord-273487-nfgjz6f9	23	2	respect	respect	NN
cord-273487-nfgjz6f9	23	3	to	to	IN
cord-273487-nfgjz6f9	23	4	the	the	DT
cord-273487-nfgjz6f9	23	5	latter	latter	JJ
cord-273487-nfgjz6f9	23	6	,	,	,
cord-273487-nfgjz6f9	23	7	we	-PRON-	PRP
cord-273487-nfgjz6f9	23	8	recently	recently	RB
cord-273487-nfgjz6f9	23	9	identified	identify	VBD
cord-273487-nfgjz6f9	23	10	the	the	DT
cord-273487-nfgjz6f9	23	11	nucleolar	nucleolar	NN
cord-273487-nfgjz6f9	23	12	helicase	helicase	NNP
cord-273487-nfgjz6f9	23	13	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	23	14	as	as	IN
cord-273487-nfgjz6f9	23	15	a	a	DT
cord-273487-nfgjz6f9	23	16	WNV	WNV	NNP
cord-273487-nfgjz6f9	23	17	capsid	capsid	RB
cord-273487-nfgjz6f9	23	18	-	-	HYPH
cord-273487-nfgjz6f9	23	19	binding	bind	VBG
cord-273487-nfgjz6f9	23	20	protein	protein	NN
cord-273487-nfgjz6f9	23	21	(	(	-LRB-
cord-273487-nfgjz6f9	23	22	Xu	Xu	NNP
cord-273487-nfgjz6f9	23	23	et	et	NNP
cord-273487-nfgjz6f9	23	24	al	al	NNP
cord-273487-nfgjz6f9	23	25	.	.	NNP
cord-273487-nfgjz6f9	23	26	,	,	,
cord-273487-nfgjz6f9	23	27	2011	2011	CD
cord-273487-nfgjz6f9	23	28	)	)	-RRB-
cord-273487-nfgjz6f9	23	29	.	.	.
cord-273487-nfgjz6f9	24	1	Expression	expression	NN
cord-273487-nfgjz6f9	24	2	of	of	IN
cord-273487-nfgjz6f9	24	3	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	24	4	is	be	VBZ
cord-273487-nfgjz6f9	24	5	not	not	RB
cord-273487-nfgjz6f9	24	6	required	require	VBN
cord-273487-nfgjz6f9	24	7	for	for	IN
cord-273487-nfgjz6f9	24	8	virus	virus	NN
cord-273487-nfgjz6f9	24	9	replication	replication	NN
cord-273487-nfgjz6f9	24	10	and	and	CC
cord-273487-nfgjz6f9	24	11	thus	thus	RB
cord-273487-nfgjz6f9	24	12	could	could	MD
cord-273487-nfgjz6f9	24	13	not	not	RB
cord-273487-nfgjz6f9	24	14	have	have	VB
cord-273487-nfgjz6f9	24	15	been	be	VBN
cord-273487-nfgjz6f9	24	16	identified	identify	VBN
cord-273487-nfgjz6f9	24	17	in	in	IN
cord-273487-nfgjz6f9	24	18	an	an	DT
cord-273487-nfgjz6f9	24	19	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	24	20	screen	screen	NN
cord-273487-nfgjz6f9	24	21	designed	design	VBN
cord-273487-nfgjz6f9	24	22	to	to	TO
cord-273487-nfgjz6f9	24	23	identify	identify	VB
cord-273487-nfgjz6f9	24	24	host	host	NN
cord-273487-nfgjz6f9	24	25	factors	factor	NNS
cord-273487-nfgjz6f9	24	26	that	that	WDT
cord-273487-nfgjz6f9	24	27	function	function	VBP
cord-273487-nfgjz6f9	24	28	in	in	IN
cord-273487-nfgjz6f9	24	29	this	this	DT
cord-273487-nfgjz6f9	24	30	process	process	NN
cord-273487-nfgjz6f9	24	31	.	.	.
cord-273487-nfgjz6f9	25	1	However	however	RB
cord-273487-nfgjz6f9	25	2	,	,	,
cord-273487-nfgjz6f9	25	3	expression	expression	NN
cord-273487-nfgjz6f9	25	4	of	of	IN
cord-273487-nfgjz6f9	25	5	the	the	DT
cord-273487-nfgjz6f9	25	6	nucleolar	nucleolar	JJ
cord-273487-nfgjz6f9	25	7	helicase	helicase	NNP
cord-273487-nfgjz6f9	25	8	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	25	9	is	be	VBZ
cord-273487-nfgjz6f9	25	10	important	important	JJ
cord-273487-nfgjz6f9	25	11	for	for	IN
cord-273487-nfgjz6f9	25	12	infectivity	infectivity	NN
cord-273487-nfgjz6f9	25	13	of	of	IN
cord-273487-nfgjz6f9	25	14	WNV	WNV	NNP
cord-273487-nfgjz6f9	25	15	virions	virion	NNS
cord-273487-nfgjz6f9	25	16	(	(	-LRB-
cord-273487-nfgjz6f9	26	1	Xu	Xu	NNP
cord-273487-nfgjz6f9	26	2	et	et	NNP
cord-273487-nfgjz6f9	26	3	al	al	NNP
cord-273487-nfgjz6f9	26	4	.	.	.
cord-273487-nfgjz6f9	27	1	,	,	,
cord-273487-nfgjz6f9	27	2	2011	2011	CD
cord-273487-nfgjz6f9	27	3	)	)	-RRB-
cord-273487-nfgjz6f9	27	4	.	.	.
cord-273487-nfgjz6f9	28	1	Findings	finding	NNS
cord-273487-nfgjz6f9	28	2	from	from	IN
cord-273487-nfgjz6f9	28	3	other	other	JJ
cord-273487-nfgjz6f9	28	4	laboratories	laboratory	NNS
cord-273487-nfgjz6f9	28	5	indicate	indicate	VBP
cord-273487-nfgjz6f9	28	6	that	that	IN
cord-273487-nfgjz6f9	28	7	both	both	CC
cord-273487-nfgjz6f9	28	8	cellular	cellular	JJ
cord-273487-nfgjz6f9	28	9	and	and	CC
cord-273487-nfgjz6f9	28	10	viral	viral	JJ
cord-273487-nfgjz6f9	28	11	helicases	helicase	NNS
cord-273487-nfgjz6f9	28	12	play	play	VBP
cord-273487-nfgjz6f9	28	13	critical	critical	JJ
cord-273487-nfgjz6f9	28	14	roles	role	NNS
cord-273487-nfgjz6f9	28	15	in	in	IN
cord-273487-nfgjz6f9	28	16	the	the	DT
cord-273487-nfgjz6f9	28	17	biology	biology	NN
cord-273487-nfgjz6f9	28	18	of	of	IN
cord-273487-nfgjz6f9	28	19	flaviviruses	flavivirus	NNS
cord-273487-nfgjz6f9	29	1	(	(	-LRB-
cord-273487-nfgjz6f9	29	2	Ariumi	Ariumi	NNP
cord-273487-nfgjz6f9	29	3	et	et	FW
cord-273487-nfgjz6f9	29	4	al	al	NNP
cord-273487-nfgjz6f9	29	5	.	.	NNP
cord-273487-nfgjz6f9	29	6	,	,	,
cord-273487-nfgjz6f9	29	7	2007	2007	CD
cord-273487-nfgjz6f9	30	1	;	;	:
cord-273487-nfgjz6f9	30	2	Krishnan	Krishnan	NNP
cord-273487-nfgjz6f9	30	3	et	et	NNP
cord-273487-nfgjz6f9	30	4	al	al	NNP
cord-273487-nfgjz6f9	30	5	.	.	NNP
cord-273487-nfgjz6f9	30	6	,	,	,
cord-273487-nfgjz6f9	30	7	2008	2008	CD
cord-273487-nfgjz6f9	30	8	;	;	:
cord-273487-nfgjz6f9	30	9	Mamiya	Mamiya	NNP
cord-273487-nfgjz6f9	30	10	and	and	CC
cord-273487-nfgjz6f9	30	11	Worman	Worman	NNP
cord-273487-nfgjz6f9	30	12	,	,	,
cord-273487-nfgjz6f9	30	13	1999	1999	CD
cord-273487-nfgjz6f9	30	14	;	;	:
cord-273487-nfgjz6f9	30	15	Owsianka	Owsianka	NNP
cord-273487-nfgjz6f9	30	16	and	and	CC
cord-273487-nfgjz6f9	30	17	Patel	Patel	NNP
cord-273487-nfgjz6f9	30	18	,	,	,
cord-273487-nfgjz6f9	30	19	1999	1999	CD
cord-273487-nfgjz6f9	30	20	;	;	:
cord-273487-nfgjz6f9	30	21	You	-PRON-	PRP
cord-273487-nfgjz6f9	30	22	et	et	FW
cord-273487-nfgjz6f9	30	23	al	al	NNP
cord-273487-nfgjz6f9	30	24	.	.	NNP
cord-273487-nfgjz6f9	30	25	,	,	,
cord-273487-nfgjz6f9	30	26	1999	1999	CD
cord-273487-nfgjz6f9	30	27	)	)	-RRB-
cord-273487-nfgjz6f9	30	28	.	.	.
cord-273487-nfgjz6f9	31	1	Accordingly	accordingly	RB
cord-273487-nfgjz6f9	31	2	,	,	,
cord-273487-nfgjz6f9	31	3	considerable	considerable	JJ
cord-273487-nfgjz6f9	31	4	efforts	effort	NNS
cord-273487-nfgjz6f9	31	5	have	have	VBP
cord-273487-nfgjz6f9	31	6	been	be	VBN
cord-273487-nfgjz6f9	31	7	directed	direct	VBN
cord-273487-nfgjz6f9	31	8	toward	toward	IN
cord-273487-nfgjz6f9	31	9	determining	determine	VBG
cord-273487-nfgjz6f9	31	10	the	the	DT
cord-273487-nfgjz6f9	31	11	feasibility	feasibility	NN
cord-273487-nfgjz6f9	31	12	of	of	IN
cord-273487-nfgjz6f9	31	13	targeting	target	VBG
cord-273487-nfgjz6f9	31	14	cellular	cellular	JJ
cord-273487-nfgjz6f9	31	15	and	and	CC
cord-273487-nfgjz6f9	31	16	viral	viral	JJ
cord-273487-nfgjz6f9	31	17	helicases	helicase	NNS
cord-273487-nfgjz6f9	31	18	as	as	IN
cord-273487-nfgjz6f9	31	19	a	a	DT
cord-273487-nfgjz6f9	31	20	means	means	NN
cord-273487-nfgjz6f9	31	21	to	to	TO
cord-273487-nfgjz6f9	31	22	block	block	VB
cord-273487-nfgjz6f9	31	23	viral	viral	JJ
cord-273487-nfgjz6f9	31	24	infections	infection	NNS
cord-273487-nfgjz6f9	31	25	(	(	-LRB-
cord-273487-nfgjz6f9	31	26	Geiss	Geiss	NNP
cord-273487-nfgjz6f9	31	27	et	et	NNP
cord-273487-nfgjz6f9	31	28	al	al	NNP
cord-273487-nfgjz6f9	31	29	.	.	NNP
cord-273487-nfgjz6f9	31	30	,	,	,
cord-273487-nfgjz6f9	31	31	2009	2009	CD
cord-273487-nfgjz6f9	31	32	;	;	:
cord-273487-nfgjz6f9	31	33	Kwong	Kwong	NNP
cord-273487-nfgjz6f9	31	34	et	et	NNP
cord-273487-nfgjz6f9	31	35	al	al	NNP
cord-273487-nfgjz6f9	31	36	.	.	.
cord-273487-nfgjz6f9	32	1	,	,	,
cord-273487-nfgjz6f9	32	2	2005	2005	CD
cord-273487-nfgjz6f9	32	3	;	;	:
cord-273487-nfgjz6f9	32	4	Maga	Maga	NNP
cord-273487-nfgjz6f9	32	5	et	et	NNP
cord-273487-nfgjz6f9	32	6	al	al	NNP
cord-273487-nfgjz6f9	32	7	.	.	NNP
cord-273487-nfgjz6f9	32	8	,	,	,
cord-273487-nfgjz6f9	32	9	2011	2011	CD
cord-273487-nfgjz6f9	32	10	;	;	:
cord-273487-nfgjz6f9	33	1	Stankiewicz	Stankiewicz	NNP
cord-273487-nfgjz6f9	33	2	-	-	HYPH
cord-273487-nfgjz6f9	33	3	Drogon	Drogon	NNP
cord-273487-nfgjz6f9	33	4	et	et	NNP
cord-273487-nfgjz6f9	33	5	al	al	NNP
cord-273487-nfgjz6f9	33	6	.	.	NNP
cord-273487-nfgjz6f9	33	7	,	,	,
cord-273487-nfgjz6f9	33	8	2010	2010	CD
cord-273487-nfgjz6f9	33	9	)	)	-RRB-
cord-273487-nfgjz6f9	33	10	.	.	.
cord-273487-nfgjz6f9	34	1	To	to	TO
cord-273487-nfgjz6f9	34	2	aid	aid	VB
cord-273487-nfgjz6f9	34	3	in	in	IN
cord-273487-nfgjz6f9	34	4	development	development	NN
cord-273487-nfgjz6f9	34	5	of	of	IN
cord-273487-nfgjz6f9	34	6	anti	anti	JJ
cord-273487-nfgjz6f9	34	7	-	-	JJ
cord-273487-nfgjz6f9	34	8	viral	viral	JJ
cord-273487-nfgjz6f9	34	9	therapies	therapy	NNS
cord-273487-nfgjz6f9	34	10	that	that	WDT
cord-273487-nfgjz6f9	34	11	target	target	VBP
cord-273487-nfgjz6f9	34	12	RNA	RNA	NNP
cord-273487-nfgjz6f9	34	13	helicases	helicase	NNS
cord-273487-nfgjz6f9	34	14	which	which	WDT
cord-273487-nfgjz6f9	34	15	are	be	VBP
cord-273487-nfgjz6f9	34	16	integral	integral	JJ
cord-273487-nfgjz6f9	34	17	to	to	IN
cord-273487-nfgjz6f9	34	18	flavivirus	flavivirus	JJ
cord-273487-nfgjz6f9	34	19	biology	biology	NN
cord-273487-nfgjz6f9	34	20	,	,	,
cord-273487-nfgjz6f9	34	21	it	-PRON-	PRP
cord-273487-nfgjz6f9	34	22	is	be	VBZ
cord-273487-nfgjz6f9	34	23	critical	critical	JJ
cord-273487-nfgjz6f9	34	24	to	to	TO
cord-273487-nfgjz6f9	34	25	understand	understand	VB
cord-273487-nfgjz6f9	34	26	how	how	WRB
cord-273487-nfgjz6f9	34	27	these	these	DT
cord-273487-nfgjz6f9	34	28	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	34	29	function	function	VBP
cord-273487-nfgjz6f9	34	30	in	in	IN
cord-273487-nfgjz6f9	34	31	this	this	DT
cord-273487-nfgjz6f9	34	32	capacity	capacity	NN
cord-273487-nfgjz6f9	34	33	.	.	.
cord-273487-nfgjz6f9	35	1	Indeed	indeed	RB
cord-273487-nfgjz6f9	35	2	,	,	,
cord-273487-nfgjz6f9	35	3	evidence	evidence	NN
cord-273487-nfgjz6f9	35	4	suggests	suggest	VBZ
cord-273487-nfgjz6f9	35	5	that	that	IN
cord-273487-nfgjz6f9	35	6	some	some	DT
cord-273487-nfgjz6f9	35	7	RNA	RNA	NNP
cord-273487-nfgjz6f9	35	8	helicases	helicase	NNS
cord-273487-nfgjz6f9	35	9	are	be	VBP
cord-273487-nfgjz6f9	35	10	required	require	VBN
cord-273487-nfgjz6f9	35	11	for	for	IN
cord-273487-nfgjz6f9	35	12	replication	replication	NN
cord-273487-nfgjz6f9	35	13	of	of	IN
cord-273487-nfgjz6f9	35	14	viral	viral	JJ
cord-273487-nfgjz6f9	35	15	RNA	RNA	NNP
cord-273487-nfgjz6f9	35	16	whereas	whereas	IN
cord-273487-nfgjz6f9	35	17	others	other	NNS
cord-273487-nfgjz6f9	35	18	are	be	VBP
cord-273487-nfgjz6f9	35	19	needed	need	VBN
cord-273487-nfgjz6f9	35	20	for	for	IN
cord-273487-nfgjz6f9	35	21	assembly	assembly	NN
cord-273487-nfgjz6f9	35	22	of	of	IN
cord-273487-nfgjz6f9	35	23	infectious	infectious	JJ
cord-273487-nfgjz6f9	35	24	virus	virus	NN
cord-273487-nfgjz6f9	35	25	particles	particle	NNS
cord-273487-nfgjz6f9	35	26	.	.	.
cord-273487-nfgjz6f9	36	1	In	in	IN
cord-273487-nfgjz6f9	36	2	addition	addition	NN
cord-273487-nfgjz6f9	36	3	to	to	IN
cord-273487-nfgjz6f9	36	4	serving	serve	VBG
cord-273487-nfgjz6f9	36	5	as	as	IN
cord-273487-nfgjz6f9	36	6	co	co	NNS
cord-273487-nfgjz6f9	36	7	-	-	NNS
cord-273487-nfgjz6f9	36	8	factors	factor	NNS
cord-273487-nfgjz6f9	36	9	during	during	IN
cord-273487-nfgjz6f9	36	10	virus	virus	NN
cord-273487-nfgjz6f9	36	11	replication	replication	NN
cord-273487-nfgjz6f9	36	12	and	and	CC
cord-273487-nfgjz6f9	36	13	assembly	assembly	NN
cord-273487-nfgjz6f9	36	14	,	,	,
cord-273487-nfgjz6f9	36	15	the	the	DT
cord-273487-nfgjz6f9	36	16	mechanism	mechanism	NN
cord-273487-nfgjz6f9	36	17	by	by	IN
cord-273487-nfgjz6f9	36	18	which	which	WDT
cord-273487-nfgjz6f9	36	19	a	a	DT
cord-273487-nfgjz6f9	36	20	given	give	VBN
cord-273487-nfgjz6f9	36	21	helicase	helicase	NN
cord-273487-nfgjz6f9	36	22	functions	function	NNS
cord-273487-nfgjz6f9	36	23	in	in	IN
cord-273487-nfgjz6f9	36	24	these	these	DT
cord-273487-nfgjz6f9	36	25	processes	process	NNS
cord-273487-nfgjz6f9	36	26	may	may	MD
cord-273487-nfgjz6f9	36	27	vary	vary	VB
cord-273487-nfgjz6f9	36	28	considerably	considerably	RB
cord-273487-nfgjz6f9	36	29	.	.	.
cord-273487-nfgjz6f9	37	1	Moreover	moreover	RB
cord-273487-nfgjz6f9	37	2	,	,	,
cord-273487-nfgjz6f9	37	3	in	in	IN
cord-273487-nfgjz6f9	37	4	some	some	DT
cord-273487-nfgjz6f9	37	5	cases	case	NNS
cord-273487-nfgjz6f9	37	6	the	the	DT
cord-273487-nfgjz6f9	37	7	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	37	8	activity	activity	NN
cord-273487-nfgjz6f9	37	9	of	of	IN
cord-273487-nfgjz6f9	37	10	a	a	DT
cord-273487-nfgjz6f9	37	11	helicase	helicase	NN
cord-273487-nfgjz6f9	37	12	may	may	MD
cord-273487-nfgjz6f9	37	13	not	not	RB
cord-273487-nfgjz6f9	37	14	even	even	RB
cord-273487-nfgjz6f9	37	15	be	be	VB
cord-273487-nfgjz6f9	37	16	required	require	VBN
cord-273487-nfgjz6f9	37	17	for	for	IN
cord-273487-nfgjz6f9	37	18	its	-PRON-	PRP$
cord-273487-nfgjz6f9	37	19	role	role	NN
cord-273487-nfgjz6f9	37	20	in	in	IN
cord-273487-nfgjz6f9	37	21	the	the	DT
cord-273487-nfgjz6f9	37	22	infection	infection	NN
cord-273487-nfgjz6f9	37	23	pathway	pathway	NN
cord-273487-nfgjz6f9	37	24	.	.	.
cord-273487-nfgjz6f9	38	1	For	for	IN
cord-273487-nfgjz6f9	38	2	example	example	NN
cord-273487-nfgjz6f9	38	3	,	,	,
cord-273487-nfgjz6f9	38	4	the	the	DT
cord-273487-nfgjz6f9	38	5	helicase	helicase	NN
cord-273487-nfgjz6f9	38	6	activity	activity	NN
cord-273487-nfgjz6f9	38	7	of	of	IN
cord-273487-nfgjz6f9	38	8	the	the	DT
cord-273487-nfgjz6f9	38	9	NS3	ns3	RB
cord-273487-nfgjz6f9	38	10	protein	protein	NN
cord-273487-nfgjz6f9	38	11	is	be	VBZ
cord-273487-nfgjz6f9	38	12	dispensable	dispensable	JJ
cord-273487-nfgjz6f9	38	13	for	for	IN
cord-273487-nfgjz6f9	38	14	its	-PRON-	PRP$
cord-273487-nfgjz6f9	38	15	function	function	NN
cord-273487-nfgjz6f9	38	16	assembly	assembly	NN
cord-273487-nfgjz6f9	38	17	of	of	IN
cord-273487-nfgjz6f9	38	18	infectious	infectious	JJ
cord-273487-nfgjz6f9	38	19	yellow	yellow	JJ
cord-273487-nfgjz6f9	38	20	fever	fever	NN
cord-273487-nfgjz6f9	38	21	virions	virion	NNS
cord-273487-nfgjz6f9	38	22	(	(	-LRB-
cord-273487-nfgjz6f9	38	23	Patkar	Patkar	NNP
cord-273487-nfgjz6f9	38	24	and	and	CC
cord-273487-nfgjz6f9	38	25	Kuhn	Kuhn	NNP
cord-273487-nfgjz6f9	38	26	,	,	,
cord-273487-nfgjz6f9	38	27	2008	2008	CD
cord-273487-nfgjz6f9	38	28	)	)	-RRB-
cord-273487-nfgjz6f9	38	29	.	.	.
cord-273487-nfgjz6f9	39	1	In	in	IN
cord-273487-nfgjz6f9	39	2	the	the	DT
cord-273487-nfgjz6f9	39	3	present	present	JJ
cord-273487-nfgjz6f9	39	4	study	study	NN
cord-273487-nfgjz6f9	39	5	,	,	,
cord-273487-nfgjz6f9	39	6	we	-PRON-	PRP
cord-273487-nfgjz6f9	39	7	investigated	investigate	VBD
cord-273487-nfgjz6f9	39	8	the	the	DT
cord-273487-nfgjz6f9	39	9	mechanism	mechanism	NN
cord-273487-nfgjz6f9	39	10	by	by	IN
cord-273487-nfgjz6f9	39	11	which	which	WDT
cord-273487-nfgjz6f9	39	12	the	the	DT
cord-273487-nfgjz6f9	39	13	nucleolar	nucleolar	NN
cord-273487-nfgjz6f9	39	14	helicase	helicase	NNP
cord-273487-nfgjz6f9	39	15	DDX56	ddx56	DT
cord-273487-nfgjz6f9	39	16	functions	function	NNS
cord-273487-nfgjz6f9	39	17	in	in	IN
cord-273487-nfgjz6f9	39	18	morphogenesis	morphogenesis	NN
cord-273487-nfgjz6f9	39	19	of	of	IN
cord-273487-nfgjz6f9	39	20	WNV	WNV	NNP
cord-273487-nfgjz6f9	39	21	virions	virion	NNS
cord-273487-nfgjz6f9	39	22	.	.	.
cord-273487-nfgjz6f9	40	1	Our	-PRON-	PRP$
cord-273487-nfgjz6f9	40	2	data	datum	NNS
cord-273487-nfgjz6f9	40	3	show	show	VBP
cord-273487-nfgjz6f9	40	4	that	that	IN
cord-273487-nfgjz6f9	40	5	inactivating	inactivate	VBG
cord-273487-nfgjz6f9	40	6	mutations	mutation	NNS
cord-273487-nfgjz6f9	40	7	in	in	IN
cord-273487-nfgjz6f9	40	8	the	the	DT
cord-273487-nfgjz6f9	40	9	DEAD	dead	JJ
cord-273487-nfgjz6f9	40	10	box	box	NN
cord-273487-nfgjz6f9	40	11	motif	motif	NN
cord-273487-nfgjz6f9	40	12	of	of	IN
cord-273487-nfgjz6f9	40	13	DDX56	ddx56	DT
cord-273487-nfgjz6f9	40	14	impair	impair	VB
cord-273487-nfgjz6f9	40	15	its	-PRON-	PRP$
cord-273487-nfgjz6f9	40	16	role	role	NN
cord-273487-nfgjz6f9	40	17	in	in	IN
cord-273487-nfgjz6f9	40	18	production	production	NN
cord-273487-nfgjz6f9	40	19	of	of	IN
cord-273487-nfgjz6f9	40	20	infectious	infectious	JJ
cord-273487-nfgjz6f9	40	21	WNV	WNV	NNP
cord-273487-nfgjz6f9	40	22	virions	virion	NNS
cord-273487-nfgjz6f9	40	23	.	.	.
cord-273487-nfgjz6f9	41	1	Similarly	similarly	RB
cord-273487-nfgjz6f9	41	2	,	,	,
cord-273487-nfgjz6f9	41	3	over	over	IN
cord-273487-nfgjz6f9	41	4	-	-	HYPH
cord-273487-nfgjz6f9	41	5	expression	expression	NN
cord-273487-nfgjz6f9	41	6	of	of	IN
cord-273487-nfgjz6f9	41	7	the	the	DT
cord-273487-nfgjz6f9	41	8	capsid	capsid	RB
cord-273487-nfgjz6f9	41	9	-	-	HYPH
cord-273487-nfgjz6f9	41	10	binding	bind	VBG
cord-273487-nfgjz6f9	41	11	region	region	NN
cord-273487-nfgjz6f9	41	12	of	of	IN
cord-273487-nfgjz6f9	41	13	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	41	14	has	have	VBZ
cord-273487-nfgjz6f9	41	15	a	a	DT
cord-273487-nfgjz6f9	41	16	negative	negative	JJ
cord-273487-nfgjz6f9	41	17	impact	impact	NN
cord-273487-nfgjz6f9	41	18	on	on	IN
cord-273487-nfgjz6f9	41	19	WNV	WNV	NNP
cord-273487-nfgjz6f9	41	20	infectivity	infectivity	NN
cord-273487-nfgjz6f9	41	21	.	.	.
cord-273487-nfgjz6f9	42	1	Together	together	RB
cord-273487-nfgjz6f9	42	2	,	,	,
cord-273487-nfgjz6f9	42	3	these	these	DT
cord-273487-nfgjz6f9	42	4	findings	finding	NNS
cord-273487-nfgjz6f9	42	5	are	be	VBP
cord-273487-nfgjz6f9	42	6	consistent	consistent	JJ
cord-273487-nfgjz6f9	42	7	with	with	IN
cord-273487-nfgjz6f9	42	8	a	a	DT
cord-273487-nfgjz6f9	42	9	scenario	scenario	NN
cord-273487-nfgjz6f9	42	10	in	in	IN
cord-273487-nfgjz6f9	42	11	which	which	WDT
cord-273487-nfgjz6f9	42	12	the	the	DT
cord-273487-nfgjz6f9	42	13	interaction	interaction	NN
cord-273487-nfgjz6f9	42	14	between	between	IN
cord-273487-nfgjz6f9	42	15	catalytically	catalytically	RB
cord-273487-nfgjz6f9	42	16	active	active	JJ
cord-273487-nfgjz6f9	42	17	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	42	18	and	and	CC
cord-273487-nfgjz6f9	42	19	the	the	DT
cord-273487-nfgjz6f9	42	20	WNV	WNV	NNP
cord-273487-nfgjz6f9	42	21	capsid	capsid	NN
cord-273487-nfgjz6f9	42	22	protein	protein	NN
cord-273487-nfgjz6f9	42	23	is	be	VBZ
cord-273487-nfgjz6f9	42	24	an	an	DT
cord-273487-nfgjz6f9	42	25	important	important	JJ
cord-273487-nfgjz6f9	42	26	step	step	NN
cord-273487-nfgjz6f9	42	27	during	during	IN
cord-273487-nfgjz6f9	42	28	packaging	package	VBG
cord-273487-nfgjz6f9	42	29	genomic	genomic	JJ
cord-273487-nfgjz6f9	42	30	RNA	RNA	NNP
cord-273487-nfgjz6f9	42	31	into	into	IN
cord-273487-nfgjz6f9	42	32	nascent	nascent	JJ
cord-273487-nfgjz6f9	42	33	virions	virion	NNS
cord-273487-nfgjz6f9	42	34	.	.	.
cord-273487-nfgjz6f9	43	1	As	as	IN
cord-273487-nfgjz6f9	43	2	a	a	DT
cord-273487-nfgjz6f9	43	3	first	first	JJ
cord-273487-nfgjz6f9	43	4	step	step	NN
cord-273487-nfgjz6f9	43	5	toward	toward	IN
cord-273487-nfgjz6f9	43	6	determining	determine	VBG
cord-273487-nfgjz6f9	43	7	whether	whether	IN
cord-273487-nfgjz6f9	43	8	the	the	DT
cord-273487-nfgjz6f9	43	9	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	43	10	activity	activity	NN
cord-273487-nfgjz6f9	43	11	of	of	IN
cord-273487-nfgjz6f9	43	12	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	43	13	is	be	VBZ
cord-273487-nfgjz6f9	43	14	required	require	VBN
cord-273487-nfgjz6f9	43	15	for	for	IN
cord-273487-nfgjz6f9	43	16	infectivity	infectivity	NN
cord-273487-nfgjz6f9	43	17	of	of	IN
cord-273487-nfgjz6f9	43	18	WNV	WNV	NNP
cord-273487-nfgjz6f9	43	19	particles	particle	NNS
cord-273487-nfgjz6f9	43	20	,	,	,
cord-273487-nfgjz6f9	43	21	we	-PRON-	PRP
cord-273487-nfgjz6f9	43	22	constructed	construct	VBD
cord-273487-nfgjz6f9	43	23	DDX56	ddx56	DT
cord-273487-nfgjz6f9	43	24	mutants	mutant	NNS
cord-273487-nfgjz6f9	43	25	that	that	WDT
cord-273487-nfgjz6f9	43	26	lack	lack	VBP
cord-273487-nfgjz6f9	43	27	helicase	helicase	NN
cord-273487-nfgjz6f9	43	28	function	function	NN
cord-273487-nfgjz6f9	43	29	.	.	.
cord-273487-nfgjz6f9	44	1	The	the	DT
cord-273487-nfgjz6f9	44	2	DEAD	dead	JJ
cord-273487-nfgjz6f9	44	3	box	box	NN
cord-273487-nfgjz6f9	44	4	motif	motif	NN
cord-273487-nfgjz6f9	44	5	is	be	VBZ
cord-273487-nfgjz6f9	44	6	highly	highly	RB
cord-273487-nfgjz6f9	44	7	conserved	conserve	VBN
cord-273487-nfgjz6f9	44	8	in	in	IN
cord-273487-nfgjz6f9	44	9	a	a	DT
cord-273487-nfgjz6f9	44	10	subgroup	subgroup	NN
cord-273487-nfgjz6f9	44	11	of	of	IN
cord-273487-nfgjz6f9	44	12	RNA	RNA	NNP
cord-273487-nfgjz6f9	44	13	helicases	helicase	NNS
cord-273487-nfgjz6f9	44	14	(	(	-LRB-
cord-273487-nfgjz6f9	44	15	Schmid	Schmid	NNP
cord-273487-nfgjz6f9	44	16	and	and	CC
cord-273487-nfgjz6f9	44	17	Linder	Linder	NNP
cord-273487-nfgjz6f9	44	18	,	,	,
cord-273487-nfgjz6f9	44	19	1992	1992	CD
cord-273487-nfgjz6f9	44	20	)	)	-RRB-
cord-273487-nfgjz6f9	44	21	and	and	CC
cord-273487-nfgjz6f9	44	22	mutagenesis	mutagenesis	NN
cord-273487-nfgjz6f9	44	23	studies	study	NNS
cord-273487-nfgjz6f9	44	24	have	have	VBP
cord-273487-nfgjz6f9	44	25	shown	show	VBN
cord-273487-nfgjz6f9	44	26	that	that	DT
cord-273487-nfgjz6f9	44	27	substitution	substitution	NN
cord-273487-nfgjz6f9	44	28	of	of	IN
cord-273487-nfgjz6f9	44	29	asparagine	asparagine	NN
cord-273487-nfgjz6f9	44	30	for	for	IN
cord-273487-nfgjz6f9	44	31	aspartate	aspartate	NN
cord-273487-nfgjz6f9	44	32	or	or	CC
cord-273487-nfgjz6f9	44	33	glutamine	glutamine	NN
cord-273487-nfgjz6f9	44	34	for	for	IN
cord-273487-nfgjz6f9	44	35	glutamate	glutamate	NN
cord-273487-nfgjz6f9	44	36	results	result	NNS
cord-273487-nfgjz6f9	44	37	in	in	IN
cord-273487-nfgjz6f9	44	38	complete	complete	JJ
cord-273487-nfgjz6f9	44	39	loss	loss	NN
cord-273487-nfgjz6f9	44	40	of	of	IN
cord-273487-nfgjz6f9	44	41	helicase	helicase	NN
cord-273487-nfgjz6f9	44	42	activity	activity	NN
cord-273487-nfgjz6f9	44	43	(	(	-LRB-
cord-273487-nfgjz6f9	44	44	Pause	pause	VB
cord-273487-nfgjz6f9	44	45	and	and	CC
cord-273487-nfgjz6f9	44	46	Sonenberg	Sonenberg	NNP
cord-273487-nfgjz6f9	44	47	,	,	,
cord-273487-nfgjz6f9	44	48	1992	1992	CD
cord-273487-nfgjz6f9	44	49	)	)	-RRB-
cord-273487-nfgjz6f9	44	50	.	.	.
cord-273487-nfgjz6f9	45	1	In	in	IN
cord-273487-nfgjz6f9	45	2	addition	addition	NN
cord-273487-nfgjz6f9	45	3	to	to	IN
cord-273487-nfgjz6f9	45	4	creating	create	VBG
cord-273487-nfgjz6f9	45	5	D166N	D166N	NNP
cord-273487-nfgjz6f9	45	6	and	and	CC
cord-273487-nfgjz6f9	45	7	E167Q	e167q	NN
cord-273487-nfgjz6f9	45	8	mutations	mutation	NNS
cord-273487-nfgjz6f9	45	9	in	in	IN
cord-273487-nfgjz6f9	45	10	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	45	11	,	,	,
cord-273487-nfgjz6f9	45	12	silent	silent	JJ
cord-273487-nfgjz6f9	45	13	mutations	mutation	NNS
cord-273487-nfgjz6f9	45	14	were	be	VBD
cord-273487-nfgjz6f9	45	15	introduced	introduce	VBN
cord-273487-nfgjz6f9	45	16	downstream	downstream	RB
cord-273487-nfgjz6f9	45	17	of	of	IN
cord-273487-nfgjz6f9	45	18	the	the	DT
cord-273487-nfgjz6f9	45	19	DEAD	dead	JJ
cord-273487-nfgjz6f9	45	20	box	box	NN
cord-273487-nfgjz6f9	45	21	motif	motif	NN
cord-273487-nfgjz6f9	45	22	in	in	IN
cord-273487-nfgjz6f9	45	23	an	an	DT
cord-273487-nfgjz6f9	45	24	shRNA	shrna	NN
cord-273487-nfgjz6f9	45	25	target	target	NN
cord-273487-nfgjz6f9	45	26	site	site	NN
cord-273487-nfgjz6f9	45	27	(	(	-LRB-
cord-273487-nfgjz6f9	45	28	Fig	Fig	NNP
cord-273487-nfgjz6f9	45	29	.	.	.
cord-273487-nfgjz6f9	45	30	1	1	CD
cord-273487-nfgjz6f9	45	31	)	)	-RRB-
cord-273487-nfgjz6f9	45	32	.	.	.
cord-273487-nfgjz6f9	46	1	The	the	DT
cord-273487-nfgjz6f9	46	2	latter	latter	JJ
cord-273487-nfgjz6f9	46	3	mutations	mutation	NNS
cord-273487-nfgjz6f9	46	4	allow	allow	VBP
cord-273487-nfgjz6f9	46	5	the	the	DT
cord-273487-nfgjz6f9	46	6	expression	expression	NN
cord-273487-nfgjz6f9	46	7	of	of	IN
cord-273487-nfgjz6f9	46	8	the	the	DT
cord-273487-nfgjz6f9	46	9	DEAD	dead	JJ
cord-273487-nfgjz6f9	46	10	box	box	NN
cord-273487-nfgjz6f9	46	11	mutants	mutant	NNS
cord-273487-nfgjz6f9	46	12	in	in	IN
cord-273487-nfgjz6f9	46	13	stable	stable	JJ
cord-273487-nfgjz6f9	46	14	cell	cell	NN
cord-273487-nfgjz6f9	46	15	lines	line	NNS
cord-273487-nfgjz6f9	46	16	in	in	IN
cord-273487-nfgjz6f9	46	17	which	which	WDT
cord-273487-nfgjz6f9	46	18	endogenous	endogenous	JJ
cord-273487-nfgjz6f9	46	19	levels	level	NNS
cord-273487-nfgjz6f9	46	20	of	of	IN
cord-273487-nfgjz6f9	46	21	DDX56	DDX56	NNS
cord-273487-nfgjz6f9	46	22	have	have	VBP
cord-273487-nfgjz6f9	46	23	been	be	VBN
cord-273487-nfgjz6f9	46	24	reduced	reduce	VBN
cord-273487-nfgjz6f9	46	25	by	by	IN
cord-273487-nfgjz6f9	46	26	RNA	RNA	NNP
cord-273487-nfgjz6f9	46	27	interference	interference	NN
cord-273487-nfgjz6f9	46	28	(	(	-LRB-
cord-273487-nfgjz6f9	46	29	Fig	Fig	NNP
cord-273487-nfgjz6f9	46	30	.	.	.
cord-273487-nfgjz6f9	46	31	2A	2a	CD
cord-273487-nfgjz6f9	46	32	)	)	-RRB-
cord-273487-nfgjz6f9	46	33	.	.	.
cord-273487-nfgjz6f9	47	1	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	47	2	T	t	NN
cord-273487-nfgjz6f9	47	3	cells	cell	NNS
cord-273487-nfgjz6f9	47	4	stably	stably	RB
cord-273487-nfgjz6f9	47	5	expressing	express	VBG
cord-273487-nfgjz6f9	47	6	DDX56-specific	DDX56-specific	NNS
cord-273487-nfgjz6f9	47	7	or	or	CC
cord-273487-nfgjz6f9	47	8	nonsilencing	nonsilence	VBG
cord-273487-nfgjz6f9	47	9	shRNAs	shRNAs	NNP
cord-273487-nfgjz6f9	47	10	were	be	VBD
cord-273487-nfgjz6f9	47	11	transduced	transduce	VBN
cord-273487-nfgjz6f9	47	12	with	with	IN
cord-273487-nfgjz6f9	47	13	lentiviruses	lentiviruse	NNS
cord-273487-nfgjz6f9	47	14	encoding	encode	VBG
cord-273487-nfgjz6f9	47	15	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	47	16	and	and	CC
cord-273487-nfgjz6f9	47	17	myc	myc	NNP
cord-273487-nfgjz6f9	47	18	-	-	HYPH
cord-273487-nfgjz6f9	47	19	tagged	tag	VBN
cord-273487-nfgjz6f9	47	20	wild	wild	JJ
cord-273487-nfgjz6f9	47	21	type	type	NN
cord-273487-nfgjz6f9	48	1	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	48	2	or	or	CC
cord-273487-nfgjz6f9	48	3	DEAD	dead	JJ
cord-273487-nfgjz6f9	48	4	box	box	NN
cord-273487-nfgjz6f9	48	5	mutants	mutant	NNS
cord-273487-nfgjz6f9	48	6	.	.	.
cord-273487-nfgjz6f9	49	1	Expression	expression	NN
cord-273487-nfgjz6f9	49	2	of	of	IN
cord-273487-nfgjz6f9	49	3	the	the	DT
cord-273487-nfgjz6f9	49	4	myc	myc	NNP
cord-273487-nfgjz6f9	49	5	-	-	HYPH
cord-273487-nfgjz6f9	49	6	tagged	tag	VBN
cord-273487-nfgjz6f9	49	7	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	49	8	proteins	protein	NNS
cord-273487-nfgjz6f9	49	9	was	be	VBD
cord-273487-nfgjz6f9	49	10	monitored	monitor	VBN
cord-273487-nfgjz6f9	49	11	by	by	IN
cord-273487-nfgjz6f9	49	12	immunoblot	immunoblot	NNP
cord-273487-nfgjz6f9	49	13	analyses	analysis	NNS
cord-273487-nfgjz6f9	49	14	at	at	IN
cord-273487-nfgjz6f9	49	15	48	48	CD
cord-273487-nfgjz6f9	49	16	h	h	NN
cord-273487-nfgjz6f9	49	17	post	post	NN
cord-273487-nfgjz6f9	49	18	-	-	NN
cord-273487-nfgjz6f9	49	19	transduction	transduction	NN
cord-273487-nfgjz6f9	49	20	.	.	.
cord-273487-nfgjz6f9	50	1	Immunoblot	immunoblot	NN
cord-273487-nfgjz6f9	50	2	analyses	analysis	NNS
cord-273487-nfgjz6f9	50	3	show	show	VBP
cord-273487-nfgjz6f9	50	4	that	that	IN
cord-273487-nfgjz6f9	50	5	compared	compare	VBD
cord-273487-nfgjz6f9	50	6	to	to	IN
cord-273487-nfgjz6f9	50	7	expression	expression	NN
cord-273487-nfgjz6f9	50	8	in	in	IN
cord-273487-nfgjz6f9	50	9	non	non	JJ
cord-273487-nfgjz6f9	50	10	-	-	JJ
cord-273487-nfgjz6f9	50	11	silencing	silencing	JJ
cord-273487-nfgjz6f9	50	12	(	(	-LRB-
cord-273487-nfgjz6f9	50	13	NS	NS	NNP
cord-273487-nfgjz6f9	50	14	)	)	-RRB-
cord-273487-nfgjz6f9	50	15	cells	cell	NNS
cord-273487-nfgjz6f9	50	16	,	,	,
cord-273487-nfgjz6f9	50	17	the	the	DT
cord-273487-nfgjz6f9	50	18	level	level	NN
cord-273487-nfgjz6f9	50	19	of	of	IN
cord-273487-nfgjz6f9	50	20	wild	wild	JJ
cord-273487-nfgjz6f9	50	21	type	type	NN
cord-273487-nfgjz6f9	50	22	myc	myc	NNP
cord-273487-nfgjz6f9	50	23	-	-	HYPH
cord-273487-nfgjz6f9	50	24	tagged	tag	VBN
cord-273487-nfgjz6f9	50	25	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	50	26	(	(	-LRB-
cord-273487-nfgjz6f9	50	27	WT	WT	NNP
cord-273487-nfgjz6f9	50	28	-	-	HYPH
cord-273487-nfgjz6f9	50	29	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	50	30	-	-	HYPH
cord-273487-nfgjz6f9	50	31	S	S	NNP
cord-273487-nfgjz6f9	50	32	)	)	-RRB-
cord-273487-nfgjz6f9	50	33	in	in	IN
cord-273487-nfgjz6f9	50	34	DDX56	ddx56	DT
cord-273487-nfgjz6f9	50	35	knockdown	knockdown	NN
cord-273487-nfgjz6f9	50	36	cells	cell	NNS
cord-273487-nfgjz6f9	50	37	was	be	VBD
cord-273487-nfgjz6f9	50	38	just	just	RB
cord-273487-nfgjz6f9	50	39	on	on	IN
cord-273487-nfgjz6f9	50	40	the	the	DT
cord-273487-nfgjz6f9	50	41	threshold	threshold	NN
cord-273487-nfgjz6f9	50	42	of	of	IN
cord-273487-nfgjz6f9	50	43	detection	detection	NN
cord-273487-nfgjz6f9	50	44	with	with	IN
cord-273487-nfgjz6f9	50	45	the	the	DT
cord-273487-nfgjz6f9	50	46	anti	anti	JJ
cord-273487-nfgjz6f9	50	47	-	-	JJ
cord-273487-nfgjz6f9	50	48	myc	myc	JJ
cord-273487-nfgjz6f9	50	49	antibody	antibody	NN
cord-273487-nfgjz6f9	50	50	(	(	-LRB-
cord-273487-nfgjz6f9	50	51	Fig	Fig	NNP
cord-273487-nfgjz6f9	50	52	.	.	.
cord-273487-nfgjz6f9	50	53	2B	2b	CD
cord-273487-nfgjz6f9	50	54	,	,	,
cord-273487-nfgjz6f9	50	55	lanes	lane	VBZ
cord-273487-nfgjz6f9	50	56	3	3	CD
cord-273487-nfgjz6f9	50	57	and	and	CC
cord-273487-nfgjz6f9	50	58	9	9	CD
cord-273487-nfgjz6f9	50	59	)	)	-RRB-
cord-273487-nfgjz6f9	50	60	.	.	.
cord-273487-nfgjz6f9	51	1	In	in	IN
cord-273487-nfgjz6f9	51	2	contrast	contrast	NN
cord-273487-nfgjz6f9	51	3	,	,	,
cord-273487-nfgjz6f9	51	4	the	the	DT
cord-273487-nfgjz6f9	51	5	myc	myc	NNP
cord-273487-nfgjz6f9	51	6	-	-	HYPH
cord-273487-nfgjz6f9	51	7	tagged	tag	VBN
cord-273487-nfgjz6f9	51	8	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	51	9	-	-	HYPH
cord-273487-nfgjz6f9	51	10	resistant	resistant	JJ
cord-273487-nfgjz6f9	51	11	forms	form	NNS
cord-273487-nfgjz6f9	51	12	of	of	IN
cord-273487-nfgjz6f9	51	13	wild	wild	JJ
cord-273487-nfgjz6f9	51	14	type	type	NN
cord-273487-nfgjz6f9	51	15	DDX56	ddx56	XX
cord-273487-nfgjz6f9	51	16	as	as	RB
cord-273487-nfgjz6f9	51	17	well	well	RB
cord-273487-nfgjz6f9	51	18	as	as	IN
cord-273487-nfgjz6f9	51	19	the	the	DT
cord-273487-nfgjz6f9	51	20	D166N	D166N	NNPS
cord-273487-nfgjz6f9	51	21	and	and	CC
cord-273487-nfgjz6f9	51	22	E167Q	e167q	NN
cord-273487-nfgjz6f9	51	23	mutants	mutant	NNS
cord-273487-nfgjz6f9	51	24	were	be	VBD
cord-273487-nfgjz6f9	51	25	robustly	robustly	RB
cord-273487-nfgjz6f9	51	26	expressed	express	VBN
cord-273487-nfgjz6f9	51	27	in	in	IN
cord-273487-nfgjz6f9	51	28	the	the	DT
cord-273487-nfgjz6f9	51	29	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	51	30	knockdown	knockdown	NN
cord-273487-nfgjz6f9	51	31	cells	cell	NNS
cord-273487-nfgjz6f9	51	32	(	(	-LRB-
cord-273487-nfgjz6f9	51	33	Fig	Fig	NNP
cord-273487-nfgjz6f9	51	34	.	.	.
cord-273487-nfgjz6f9	51	35	2B	2b	CD
cord-273487-nfgjz6f9	51	36	,	,	,
cord-273487-nfgjz6f9	51	37	lanes	lane	VBZ
cord-273487-nfgjz6f9	51	38	10	10	CD
cord-273487-nfgjz6f9	51	39	-	-	SYM
cord-273487-nfgjz6f9	51	40	12	12	CD
cord-273487-nfgjz6f9	51	41	)	)	-RRB-
cord-273487-nfgjz6f9	51	42	.	.	.
cord-273487-nfgjz6f9	52	1	These	these	DT
cord-273487-nfgjz6f9	52	2	data	datum	NNS
cord-273487-nfgjz6f9	52	3	demonstrate	demonstrate	VBP
cord-273487-nfgjz6f9	52	4	that	that	IN
cord-273487-nfgjz6f9	52	5	mutant	mutant	JJ
cord-273487-nfgjz6f9	52	6	versions	version	NNS
cord-273487-nfgjz6f9	52	7	of	of	IN
cord-273487-nfgjz6f9	52	8	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	52	9	are	be	VBP
cord-273487-nfgjz6f9	52	10	stable	stable	JJ
cord-273487-nfgjz6f9	52	11	in	in	IN
cord-273487-nfgjz6f9	52	12	a	a	DT
cord-273487-nfgjz6f9	52	13	cellular	cellular	JJ
cord-273487-nfgjz6f9	52	14	background	background	NN
cord-273487-nfgjz6f9	52	15	in	in	IN
cord-273487-nfgjz6f9	52	16	which	which	WDT
cord-273487-nfgjz6f9	52	17	endogenous	endogenous	JJ
cord-273487-nfgjz6f9	52	18	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	52	19	is	be	VBZ
cord-273487-nfgjz6f9	52	20	depleted	deplete	VBN
cord-273487-nfgjz6f9	52	21	by	by	IN
cord-273487-nfgjz6f9	52	22	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	52	23	.	.	.
cord-273487-nfgjz6f9	53	1	DEAD	dead	JJ
cord-273487-nfgjz6f9	53	2	box	box	NN
cord-273487-nfgjz6f9	53	3	mutants	mutant	NNS
cord-273487-nfgjz6f9	53	4	are	be	VBP
cord-273487-nfgjz6f9	53	5	correctly	correctly	RB
cord-273487-nfgjz6f9	53	6	targeted	target	VBN
cord-273487-nfgjz6f9	53	7	to	to	IN
cord-273487-nfgjz6f9	53	8	the	the	DT
cord-273487-nfgjz6f9	53	9	nucleolus	nucleolus	NN
cord-273487-nfgjz6f9	54	1	Next	next	RB
cord-273487-nfgjz6f9	54	2	,	,	,
cord-273487-nfgjz6f9	54	3	it	-PRON-	PRP
cord-273487-nfgjz6f9	54	4	was	be	VBD
cord-273487-nfgjz6f9	54	5	important	important	JJ
cord-273487-nfgjz6f9	54	6	to	to	TO
cord-273487-nfgjz6f9	54	7	demonstrate	demonstrate	VB
cord-273487-nfgjz6f9	54	8	that	that	IN
cord-273487-nfgjz6f9	54	9	the	the	DT
cord-273487-nfgjz6f9	54	10	DEAD	dead	JJ
cord-273487-nfgjz6f9	54	11	box	box	NN
cord-273487-nfgjz6f9	54	12	mutants	mutant	NNS
cord-273487-nfgjz6f9	54	13	were	be	VBD
cord-273487-nfgjz6f9	54	14	correctly	correctly	RB
cord-273487-nfgjz6f9	54	15	targeted	target	VBN
cord-273487-nfgjz6f9	54	16	to	to	IN
cord-273487-nfgjz6f9	54	17	the	the	DT
cord-273487-nfgjz6f9	54	18	nucleolus	nucleolus	NN
cord-273487-nfgjz6f9	54	19	similar	similar	JJ
cord-273487-nfgjz6f9	54	20	to	to	IN
cord-273487-nfgjz6f9	54	21	wild	wild	JJ
cord-273487-nfgjz6f9	54	22	type	type	NN
cord-273487-nfgjz6f9	55	1	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	55	2	(	(	-LRB-
cord-273487-nfgjz6f9	55	3	Zirwes	Zirwes	NNP
cord-273487-nfgjz6f9	55	4	et	et	FW
cord-273487-nfgjz6f9	55	5	al	al	NNP
cord-273487-nfgjz6f9	55	6	.	.	NNP
cord-273487-nfgjz6f9	55	7	,	,	,
cord-273487-nfgjz6f9	55	8	2000	2000	CD
cord-273487-nfgjz6f9	55	9	)	)	-RRB-
cord-273487-nfgjz6f9	55	10	.	.	.
cord-273487-nfgjz6f9	56	1	Mock	Mock	NNP
cord-273487-nfgjz6f9	56	2	-	-	:
cord-273487-nfgjz6f9	56	3	and	and	CC
cord-273487-nfgjz6f9	56	4	WNV	WNV	NNP
cord-273487-nfgjz6f9	56	5	-	-	HYPH
cord-273487-nfgjz6f9	56	6	infected	infect	VBN
cord-273487-nfgjz6f9	56	7	A549	a549	JJ
cord-273487-nfgjz6f9	56	8	cells	cell	NNS
cord-273487-nfgjz6f9	56	9	were	be	VBD
cord-273487-nfgjz6f9	56	10	transfected	transfecte	VBN
cord-273487-nfgjz6f9	56	11	with	with	IN
cord-273487-nfgjz6f9	56	12	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	56	13	encoding	encode	VBG
cord-273487-nfgjz6f9	56	14	wild	wild	JJ
cord-273487-nfgjz6f9	56	15	type	type	NN
cord-273487-nfgjz6f9	56	16	or	or	CC
cord-273487-nfgjz6f9	56	17	DEAD	dead	JJ
cord-273487-nfgjz6f9	56	18	box	box	NN
cord-273487-nfgjz6f9	56	19	mutants	mutant	NNS
cord-273487-nfgjz6f9	56	20	of	of	IN
cord-273487-nfgjz6f9	56	21	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	56	22	.	.	.
cord-273487-nfgjz6f9	57	1	As	as	IN
cord-273487-nfgjz6f9	57	2	evidenced	evidence	VBN
cord-273487-nfgjz6f9	57	3	by	by	IN
cord-273487-nfgjz6f9	57	4	colocalization	colocalization	NN
cord-273487-nfgjz6f9	57	5	with	with	IN
cord-273487-nfgjz6f9	57	6	nucleolin	nucleolin	NNP
cord-273487-nfgjz6f9	57	7	,	,	,
cord-273487-nfgjz6f9	57	8	both	both	DT
cord-273487-nfgjz6f9	57	9	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	57	10	-	-	HYPH
cord-273487-nfgjz6f9	57	11	sensitive	sensitive	JJ
cord-273487-nfgjz6f9	57	12	and	and	CC
cord-273487-nfgjz6f9	57	13	-resistant	-resistant	JJ
cord-273487-nfgjz6f9	57	14	forms	form	NNS
cord-273487-nfgjz6f9	57	15	of	of	IN
cord-273487-nfgjz6f9	57	16	myctagged	myctagge	VBN
cord-273487-nfgjz6f9	58	1	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	58	2	are	be	VBP
cord-273487-nfgjz6f9	58	3	targeted	target	VBN
cord-273487-nfgjz6f9	58	4	to	to	IN
cord-273487-nfgjz6f9	58	5	the	the	DT
cord-273487-nfgjz6f9	58	6	nucleoli	nucleoli	NNP
cord-273487-nfgjz6f9	59	1	(	(	-LRB-
cord-273487-nfgjz6f9	59	2	Fig	Fig	NNP
cord-273487-nfgjz6f9	59	3	.	.	.
cord-273487-nfgjz6f9	59	4	3	3	CD
cord-273487-nfgjz6f9	59	5	)	)	-RRB-
cord-273487-nfgjz6f9	59	6	.	.	.
cord-273487-nfgjz6f9	60	1	Similarly	similarly	RB
cord-273487-nfgjz6f9	60	2	,	,	,
cord-273487-nfgjz6f9	60	3	the	the	DT
cord-273487-nfgjz6f9	60	4	DEAD	dead	JJ
cord-273487-nfgjz6f9	60	5	box	box	NN
cord-273487-nfgjz6f9	60	6	mutants	mutant	NNS
cord-273487-nfgjz6f9	60	7	D166N	D166N	NNPS
cord-273487-nfgjz6f9	60	8	and	and	CC
cord-273487-nfgjz6f9	60	9	E167Q	E167Q	NNP
cord-273487-nfgjz6f9	60	10	localized	localize	VBN
cord-273487-nfgjz6f9	60	11	to	to	IN
cord-273487-nfgjz6f9	60	12	nuclei	nucleus	NNS
cord-273487-nfgjz6f9	60	13	of	of	IN
cord-273487-nfgjz6f9	60	14	A549	a549	JJ
cord-273487-nfgjz6f9	60	15	cells	cell	NNS
cord-273487-nfgjz6f9	60	16	.	.	.
cord-273487-nfgjz6f9	61	1	These	these	DT
cord-273487-nfgjz6f9	61	2	data	datum	NNS
cord-273487-nfgjz6f9	61	3	confirm	confirm	VBP
cord-273487-nfgjz6f9	61	4	that	that	IN
cord-273487-nfgjz6f9	61	5	mutations	mutation	NNS
cord-273487-nfgjz6f9	61	6	in	in	IN
cord-273487-nfgjz6f9	61	7	the	the	DT
cord-273487-nfgjz6f9	61	8	DEAD	dead	JJ
cord-273487-nfgjz6f9	61	9	box	box	NN
cord-273487-nfgjz6f9	61	10	motif	motif	NN
cord-273487-nfgjz6f9	61	11	or	or	CC
cord-273487-nfgjz6f9	61	12	shRNA	shrna	NN
cord-273487-nfgjz6f9	61	13	targeting	target	VBG
cord-273487-nfgjz6f9	61	14	sites	site	NNS
cord-273487-nfgjz6f9	61	15	within	within	IN
cord-273487-nfgjz6f9	61	16	the	the	DT
cord-273487-nfgjz6f9	61	17	DDX56	ddx56	DT
cord-273487-nfgjz6f9	61	18	open	open	JJ
cord-273487-nfgjz6f9	61	19	reading	reading	NN
cord-273487-nfgjz6f9	61	20	frame	frame	NN
cord-273487-nfgjz6f9	61	21	do	do	VBP
cord-273487-nfgjz6f9	61	22	not	not	RB
cord-273487-nfgjz6f9	61	23	alter	alter	VB
cord-273487-nfgjz6f9	61	24	targeting	targeting	NN
cord-273487-nfgjz6f9	61	25	of	of	IN
cord-273487-nfgjz6f9	61	26	the	the	DT
cord-273487-nfgjz6f9	61	27	helicase	helicase	NN
cord-273487-nfgjz6f9	61	28	.	.	.
cord-273487-nfgjz6f9	62	1	To	to	TO
cord-273487-nfgjz6f9	62	2	determine	determine	VB
cord-273487-nfgjz6f9	62	3	whether	whether	IN
cord-273487-nfgjz6f9	62	4	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	62	5	activity	activity	NN
cord-273487-nfgjz6f9	62	6	of	of	IN
cord-273487-nfgjz6f9	62	7	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	62	8	was	be	VBD
cord-273487-nfgjz6f9	62	9	important	important	JJ
cord-273487-nfgjz6f9	62	10	for	for	IN
cord-273487-nfgjz6f9	62	11	viral	viral	JJ
cord-273487-nfgjz6f9	62	12	gene	gene	NN
cord-273487-nfgjz6f9	62	13	expression	expression	NN
cord-273487-nfgjz6f9	62	14	and/or	and/or	CC
cord-273487-nfgjz6f9	62	15	infectivity	infectivity	NN
cord-273487-nfgjz6f9	62	16	of	of	IN
cord-273487-nfgjz6f9	62	17	WNV	WNV	NNP
cord-273487-nfgjz6f9	62	18	,	,	,
cord-273487-nfgjz6f9	62	19	DDX56	ddx56	DT
cord-273487-nfgjz6f9	62	20	knockdown	knockdown	NN
cord-273487-nfgjz6f9	62	21	cells	cell	NNS
cord-273487-nfgjz6f9	62	22	expressing	express	VBG
cord-273487-nfgjz6f9	62	23	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	62	24	-	-	HYPH
cord-273487-nfgjz6f9	62	25	sensitive	sensitive	JJ
cord-273487-nfgjz6f9	62	26	or	or	CC
cord-273487-nfgjz6f9	62	27	resistant	resistant	JJ
cord-273487-nfgjz6f9	62	28	forms	form	NNS
cord-273487-nfgjz6f9	62	29	of	of	IN
cord-273487-nfgjz6f9	62	30	myc	myc	NNP
cord-273487-nfgjz6f9	62	31	-	-	HYPH
cord-273487-nfgjz6f9	62	32	tagged	tag	VBN
cord-273487-nfgjz6f9	62	33	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	62	34	proteins	protein	NNS
cord-273487-nfgjz6f9	62	35	were	be	VBD
cord-273487-nfgjz6f9	62	36	infected	infect	VBN
cord-273487-nfgjz6f9	62	37	with	with	IN
cord-273487-nfgjz6f9	62	38	WNV	WNV	NNP
cord-273487-nfgjz6f9	62	39	.	.	.
cord-273487-nfgjz6f9	63	1	At	at	IN
cord-273487-nfgjz6f9	63	2	48	48	CD
cord-273487-nfgjz6f9	63	3	h	h	NN
cord-273487-nfgjz6f9	63	4	post	post	NN
cord-273487-nfgjz6f9	63	5	-	-	NN
cord-273487-nfgjz6f9	63	6	infection	infection	NN
cord-273487-nfgjz6f9	63	7	,	,	,
cord-273487-nfgjz6f9	63	8	cell	cell	NN
cord-273487-nfgjz6f9	63	9	lysates	lysate	NNS
cord-273487-nfgjz6f9	63	10	and	and	CC
cord-273487-nfgjz6f9	63	11	supernatants	supernatant	NNS
cord-273487-nfgjz6f9	63	12	were	be	VBD
cord-273487-nfgjz6f9	63	13	subjected	subject	VBN
cord-273487-nfgjz6f9	63	14	to	to	IN
cord-273487-nfgjz6f9	63	15	immunoblot	immunoblot	NNP
cord-273487-nfgjz6f9	63	16	analyses	analysis	NNS
cord-273487-nfgjz6f9	63	17	and	and	CC
cord-273487-nfgjz6f9	63	18	plaque	plaque	NN
cord-273487-nfgjz6f9	63	19	assays	assay	NNS
cord-273487-nfgjz6f9	63	20	,	,	,
cord-273487-nfgjz6f9	63	21	respectively	respectively	RB
cord-273487-nfgjz6f9	63	22	.	.	.
cord-273487-nfgjz6f9	64	1	The	the	DT
cord-273487-nfgjz6f9	64	2	immunoblot	immunoblot	NNS
cord-273487-nfgjz6f9	64	3	in	in	IN
cord-273487-nfgjz6f9	64	4	Fig	Fig	NNP
cord-273487-nfgjz6f9	64	5	.	.	.
cord-273487-nfgjz6f9	64	6	4A	4A	NNP
cord-273487-nfgjz6f9	64	7	shows	show	VBZ
cord-273487-nfgjz6f9	64	8	that	that	IN
cord-273487-nfgjz6f9	64	9	based	base	VBN
cord-273487-nfgjz6f9	64	10	on	on	IN
cord-273487-nfgjz6f9	64	11	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	64	12	expression	expression	NN
cord-273487-nfgjz6f9	64	13	,	,	,
cord-273487-nfgjz6f9	64	14	similar	similar	JJ
cord-273487-nfgjz6f9	64	15	levels	level	NNS
cord-273487-nfgjz6f9	64	16	of	of	IN
cord-273487-nfgjz6f9	64	17	transduction	transduction	NN
cord-273487-nfgjz6f9	64	18	efficiency	efficiency	NN
cord-273487-nfgjz6f9	64	19	were	be	VBD
cord-273487-nfgjz6f9	64	20	achieved	achieve	VBN
cord-273487-nfgjz6f9	64	21	for	for	IN
cord-273487-nfgjz6f9	64	22	all	all	DT
cord-273487-nfgjz6f9	64	23	of	of	IN
cord-273487-nfgjz6f9	64	24	the	the	DT
cord-273487-nfgjz6f9	64	25	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	64	26	constructs	construct	NNS
cord-273487-nfgjz6f9	64	27	.	.	.
cord-273487-nfgjz6f9	65	1	As	as	IN
cord-273487-nfgjz6f9	65	2	expected	expect	VBN
cord-273487-nfgjz6f9	65	3	,	,	,
cord-273487-nfgjz6f9	65	4	only	only	RB
cord-273487-nfgjz6f9	65	5	the	the	DT
cord-273487-nfgjz6f9	65	6	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	65	7	-	-	HYPH
cord-273487-nfgjz6f9	65	8	resistant	resistant	JJ
cord-273487-nfgjz6f9	65	9	forms	form	NNS
cord-273487-nfgjz6f9	65	10	of	of	IN
cord-273487-nfgjz6f9	65	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	65	12	were	be	VBD
cord-273487-nfgjz6f9	65	13	detected	detect	VBN
cord-273487-nfgjz6f9	65	14	by	by	IN
cord-273487-nfgjz6f9	65	15	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	65	16	with	with	IN
cord-273487-nfgjz6f9	65	17	antimyc	antimyc	NNP
cord-273487-nfgjz6f9	65	18	.	.	.
cord-273487-nfgjz6f9	66	1	In	in	IN
cord-273487-nfgjz6f9	66	2	agreement	agreement	NN
cord-273487-nfgjz6f9	66	3	with	with	IN
cord-273487-nfgjz6f9	66	4	a	a	DT
cord-273487-nfgjz6f9	66	5	recent	recent	JJ
cord-273487-nfgjz6f9	66	6	report	report	NN
cord-273487-nfgjz6f9	66	7	from	from	IN
cord-273487-nfgjz6f9	66	8	our	-PRON-	PRP$
cord-273487-nfgjz6f9	66	9	laboratory	laboratory	NN
cord-273487-nfgjz6f9	66	10	(	(	-LRB-
cord-273487-nfgjz6f9	66	11	Xu	Xu	NNP
cord-273487-nfgjz6f9	66	12	et	et	NNP
cord-273487-nfgjz6f9	66	13	al	al	NNP
cord-273487-nfgjz6f9	66	14	.	.	NNP
cord-273487-nfgjz6f9	66	15	,	,	,
cord-273487-nfgjz6f9	66	16	2011	2011	CD
cord-273487-nfgjz6f9	66	17	)	)	-RRB-
cord-273487-nfgjz6f9	66	18	,	,	,
cord-273487-nfgjz6f9	66	19	titers	titer	NNS
cord-273487-nfgjz6f9	66	20	of	of	IN
cord-273487-nfgjz6f9	66	21	WNV	WNV	NNP
cord-273487-nfgjz6f9	66	22	from	from	IN
cord-273487-nfgjz6f9	66	23	DDX56	ddx56	DT
cord-273487-nfgjz6f9	66	24	depleted	deplete	VBN
cord-273487-nfgjz6f9	66	25	cells	cell	NNS
cord-273487-nfgjz6f9	66	26	were	be	VBD
cord-273487-nfgjz6f9	66	27	reduced	reduce	VBN
cord-273487-nfgjz6f9	66	28	more	more	JJR
cord-273487-nfgjz6f9	66	29	than	than	IN
cord-273487-nfgjz6f9	66	30	100	100	CD
cord-273487-nfgjz6f9	66	31	fold	fold	NN
cord-273487-nfgjz6f9	66	32	compared	compare	VBN
cord-273487-nfgjz6f9	66	33	to	to	IN
cord-273487-nfgjz6f9	66	34	those	those	DT
cord-273487-nfgjz6f9	66	35	from	from	IN
cord-273487-nfgjz6f9	66	36	nonsilencing	nonsilence	VBG
cord-273487-nfgjz6f9	66	37	controls	control	NNS
cord-273487-nfgjz6f9	66	38	(	(	-LRB-
cord-273487-nfgjz6f9	66	39	Fig	Fig	NNP
cord-273487-nfgjz6f9	66	40	.	.	.
cord-273487-nfgjz6f9	66	41	4B	4b	CD
cord-273487-nfgjz6f9	66	42	)	)	-RRB-
cord-273487-nfgjz6f9	66	43	.	.	.
cord-273487-nfgjz6f9	67	1	However	however	RB
cord-273487-nfgjz6f9	67	2	,	,	,
cord-273487-nfgjz6f9	67	3	infection	infection	NN
cord-273487-nfgjz6f9	67	4	of	of	IN
cord-273487-nfgjz6f9	67	5	cells	cell	NNS
cord-273487-nfgjz6f9	67	6	expressing	express	VBG
cord-273487-nfgjz6f9	67	7	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	67	8	-	-	HYPH
cord-273487-nfgjz6f9	67	9	resistant	resistant	JJ
cord-273487-nfgjz6f9	67	10	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	67	11	resulted	result	VBD
cord-273487-nfgjz6f9	67	12	in	in	IN
cord-273487-nfgjz6f9	67	13	normal	normal	JJ
cord-273487-nfgjz6f9	67	14	viral	viral	JJ
cord-273487-nfgjz6f9	67	15	titers	titer	NNS
cord-273487-nfgjz6f9	67	16	,	,	,
cord-273487-nfgjz6f9	67	17	which	which	WDT
cord-273487-nfgjz6f9	67	18	were	be	VBD
cord-273487-nfgjz6f9	67	19	well	well	RB
cord-273487-nfgjz6f9	67	20	over	over	IN
cord-273487-nfgjz6f9	67	21	1	1	CD
cord-273487-nfgjz6f9	67	22	Â	â	CD
cord-273487-nfgjz6f9	67	23	10	10	CD
cord-273487-nfgjz6f9	67	24	8	8	CD
cord-273487-nfgjz6f9	67	25	pfu	pfu	NN
cord-273487-nfgjz6f9	67	26	/	/	SYM
cord-273487-nfgjz6f9	67	27	ml	ml	NN
cord-273487-nfgjz6f9	67	28	.	.	.
cord-273487-nfgjz6f9	68	1	In	in	IN
cord-273487-nfgjz6f9	68	2	contrast	contrast	NN
cord-273487-nfgjz6f9	68	3	,	,	,
cord-273487-nfgjz6f9	68	4	infection	infection	NN
cord-273487-nfgjz6f9	68	5	of	of	IN
cord-273487-nfgjz6f9	68	6	cells	cell	NNS
cord-273487-nfgjz6f9	68	7	expressing	express	VBG
cord-273487-nfgjz6f9	68	8	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	68	9	-	-	HYPH
cord-273487-nfgjz6f9	68	10	sensitive	sensitive	JJ
cord-273487-nfgjz6f9	68	11	DDX56	ddx56	XX
cord-273487-nfgjz6f9	68	12	or	or	CC
cord-273487-nfgjz6f9	68	13	DEAD	dead	JJ
cord-273487-nfgjz6f9	68	14	box	box	NN
cord-273487-nfgjz6f9	68	15	mutants	mutant	NNS
cord-273487-nfgjz6f9	68	16	produced	produce	VBD
cord-273487-nfgjz6f9	68	17	viral	viral	JJ
cord-273487-nfgjz6f9	68	18	titers	titer	NNS
cord-273487-nfgjz6f9	68	19	that	that	WDT
cord-273487-nfgjz6f9	68	20	were	be	VBD
cord-273487-nfgjz6f9	68	21	similar	similar	JJ
cord-273487-nfgjz6f9	68	22	to	to	IN
cord-273487-nfgjz6f9	68	23	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	68	24	knockdown	knockdown	NN
cord-273487-nfgjz6f9	68	25	cells	cell	NNS
cord-273487-nfgjz6f9	68	26	that	that	WDT
cord-273487-nfgjz6f9	68	27	had	have	VBD
cord-273487-nfgjz6f9	68	28	been	be	VBN
cord-273487-nfgjz6f9	68	29	transduced	transduce	VBN
cord-273487-nfgjz6f9	68	30	with	with	IN
cord-273487-nfgjz6f9	68	31	a	a	DT
cord-273487-nfgjz6f9	68	32	lentivirus	lentivirus	NN
cord-273487-nfgjz6f9	68	33	encoding	encode	VBG
cord-273487-nfgjz6f9	68	34	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	68	35	only	only	RB
cord-273487-nfgjz6f9	68	36	.	.	.
cord-273487-nfgjz6f9	69	1	Capsid	capsid	JJ
cord-273487-nfgjz6f9	69	2	protein	protein	NN
cord-273487-nfgjz6f9	69	3	was	be	VBD
cord-273487-nfgjz6f9	69	4	efficiently	efficiently	RB
cord-273487-nfgjz6f9	69	5	co	co	JJ
cord-273487-nfgjz6f9	69	6	-	-	JJ
cord-273487-nfgjz6f9	69	7	immunoprecipitated	immunoprecipitated	JJ
cord-273487-nfgjz6f9	69	8	with	with	IN
cord-273487-nfgjz6f9	69	9	D166N	D166N	NNP
cord-273487-nfgjz6f9	69	10	and	and	CC
cord-273487-nfgjz6f9	69	11	E167Q	e167q	NN
cord-273487-nfgjz6f9	69	12	mutants	mutant	NNS
cord-273487-nfgjz6f9	69	13	(	(	-LRB-
cord-273487-nfgjz6f9	69	14	Fig	Fig	NNP
cord-273487-nfgjz6f9	69	15	.	.	.
cord-273487-nfgjz6f9	69	16	4C	4c	CD
cord-273487-nfgjz6f9	69	17	)	)	-RRB-
cord-273487-nfgjz6f9	69	18	and	and	CC
cord-273487-nfgjz6f9	69	19	thus	thus	RB
cord-273487-nfgjz6f9	69	20	the	the	DT
cord-273487-nfgjz6f9	69	21	failure	failure	NN
cord-273487-nfgjz6f9	69	22	of	of	IN
cord-273487-nfgjz6f9	69	23	these	these	DT
cord-273487-nfgjz6f9	69	24	DEAD	dead	JJ
cord-273487-nfgjz6f9	69	25	box	box	NN
cord-273487-nfgjz6f9	69	26	mutants	mutant	NNS
cord-273487-nfgjz6f9	69	27	to	to	TO
cord-273487-nfgjz6f9	69	28	complement	complement	VB
cord-273487-nfgjz6f9	69	29	the	the	DT
cord-273487-nfgjz6f9	69	30	production	production	NN
cord-273487-nfgjz6f9	69	31	of	of	IN
cord-273487-nfgjz6f9	69	32	Fig	Fig	NNP
cord-273487-nfgjz6f9	69	33	.	.	.
cord-273487-nfgjz6f9	70	1	1	1	LS
cord-273487-nfgjz6f9	70	2	.	.	.
cord-273487-nfgjz6f9	71	1	Construction	construction	NN
cord-273487-nfgjz6f9	71	2	of	of	IN
cord-273487-nfgjz6f9	71	3	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	71	4	-	-	HYPH
cord-273487-nfgjz6f9	71	5	resistant	resistant	JJ
cord-273487-nfgjz6f9	71	6	forms	form	NNS
cord-273487-nfgjz6f9	71	7	of	of	IN
cord-273487-nfgjz6f9	71	8	DDX56	ddx56	DT
cord-273487-nfgjz6f9	71	9	with	with	IN
cord-273487-nfgjz6f9	71	10	mutations	mutation	NNS
cord-273487-nfgjz6f9	71	11	in	in	IN
cord-273487-nfgjz6f9	71	12	the	the	DT
cord-273487-nfgjz6f9	71	13	DEAD	dead	JJ
cord-273487-nfgjz6f9	71	14	box	box	NN
cord-273487-nfgjz6f9	71	15	motif	motif	NN
cord-273487-nfgjz6f9	71	16	.	.	.
cord-273487-nfgjz6f9	72	1	Aspartate	aspartate	NN
cord-273487-nfgjz6f9	72	2	(	(	-LRB-
cord-273487-nfgjz6f9	72	3	D	D	NNP
cord-273487-nfgjz6f9	72	4	)	)	-RRB-
cord-273487-nfgjz6f9	72	5	and	and	CC
cord-273487-nfgjz6f9	72	6	glutamate	glutamate	NN
cord-273487-nfgjz6f9	72	7	(	(	-LRB-
cord-273487-nfgjz6f9	72	8	E	e	NN
cord-273487-nfgjz6f9	72	9	)	)	-RRB-
cord-273487-nfgjz6f9	72	10	residues	residue	NNS
cord-273487-nfgjz6f9	72	11	in	in	IN
cord-273487-nfgjz6f9	72	12	the	the	DT
cord-273487-nfgjz6f9	72	13	DEAD	dead	JJ
cord-273487-nfgjz6f9	72	14	box	box	NN
cord-273487-nfgjz6f9	72	15	motif	motif	NN
cord-273487-nfgjz6f9	72	16	of	of	IN
cord-273487-nfgjz6f9	72	17	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	72	18	were	be	VBD
cord-273487-nfgjz6f9	72	19	changed	change	VBN
cord-273487-nfgjz6f9	72	20	to	to	IN
cord-273487-nfgjz6f9	72	21	asparagine	asparagine	NN
cord-273487-nfgjz6f9	72	22	(	(	-LRB-
cord-273487-nfgjz6f9	72	23	N	N	NNP
cord-273487-nfgjz6f9	72	24	)	)	-RRB-
cord-273487-nfgjz6f9	72	25	and	and	CC
cord-273487-nfgjz6f9	72	26	glutamine	glutamine	NN
cord-273487-nfgjz6f9	72	27	(	(	-LRB-
cord-273487-nfgjz6f9	72	28	Q	Q	NNP
cord-273487-nfgjz6f9	72	29	)	)	-RRB-
cord-273487-nfgjz6f9	72	30	to	to	TO
cord-273487-nfgjz6f9	72	31	produce	produce	VB
cord-273487-nfgjz6f9	72	32	D166N	D166N	NNP
cord-273487-nfgjz6f9	72	33	and	and	CC
cord-273487-nfgjz6f9	72	34	E167Q	e167q	NN
cord-273487-nfgjz6f9	72	35	mutants	mutant	NNS
cord-273487-nfgjz6f9	72	36	,	,	,
cord-273487-nfgjz6f9	72	37	respectively	respectively	RB
cord-273487-nfgjz6f9	72	38	.	.	.
cord-273487-nfgjz6f9	73	1	In	in	IN
cord-273487-nfgjz6f9	73	2	addition	addition	NN
cord-273487-nfgjz6f9	73	3	,	,	,
cord-273487-nfgjz6f9	73	4	silent	silent	JJ
cord-273487-nfgjz6f9	73	5	mutations	mutation	NNS
cord-273487-nfgjz6f9	73	6	were	be	VBD
cord-273487-nfgjz6f9	73	7	introduced	introduce	VBN
cord-273487-nfgjz6f9	73	8	into	into	IN
cord-273487-nfgjz6f9	73	9	siRNA	sirna	NN
cord-273487-nfgjz6f9	73	10	-	-	HYPH
cord-273487-nfgjz6f9	73	11	binding	bind	VBG
cord-273487-nfgjz6f9	73	12	sites	site	NNS
cord-273487-nfgjz6f9	73	13	to	to	TO
cord-273487-nfgjz6f9	73	14	make	make	VB
cord-273487-nfgjz6f9	73	15	the	the	DT
cord-273487-nfgjz6f9	73	16	resulting	result	VBG
cord-273487-nfgjz6f9	73	17	constructs	construct	NNS
cord-273487-nfgjz6f9	73	18	resistant	resistant	JJ
cord-273487-nfgjz6f9	73	19	to	to	IN
cord-273487-nfgjz6f9	73	20	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	73	21	.	.	.
cord-273487-nfgjz6f9	74	1	All	all	DT
cord-273487-nfgjz6f9	74	2	constructs	construct	NNS
cord-273487-nfgjz6f9	74	3	contain	contain	VBP
cord-273487-nfgjz6f9	74	4	a	a	DT
cord-273487-nfgjz6f9	74	5	myc	myc	NN
cord-273487-nfgjz6f9	74	6	tag	tag	NN
cord-273487-nfgjz6f9	74	7	at	at	IN
cord-273487-nfgjz6f9	74	8	the	the	DT
cord-273487-nfgjz6f9	74	9	C	c	NN
cord-273487-nfgjz6f9	74	10	-	-	HYPH
cord-273487-nfgjz6f9	74	11	terminus	terminus	NN
cord-273487-nfgjz6f9	74	12	.	.	.
cord-273487-nfgjz6f9	75	1	infectious	infectious	JJ
cord-273487-nfgjz6f9	75	2	WNV	WNV	NNP
cord-273487-nfgjz6f9	75	3	virions	virion	NNS
cord-273487-nfgjz6f9	75	4	was	be	VBD
cord-273487-nfgjz6f9	75	5	not	not	RB
cord-273487-nfgjz6f9	75	6	due	due	JJ
cord-273487-nfgjz6f9	75	7	to	to	IN
cord-273487-nfgjz6f9	75	8	an	an	DT
cord-273487-nfgjz6f9	75	9	inability	inability	NN
cord-273487-nfgjz6f9	75	10	to	to	TO
cord-273487-nfgjz6f9	75	11	bind	bind	VB
cord-273487-nfgjz6f9	75	12	capsid	capsid	NN
cord-273487-nfgjz6f9	75	13	.	.	.
cord-273487-nfgjz6f9	76	1	Despite	despite	IN
cord-273487-nfgjz6f9	76	2	the	the	DT
cord-273487-nfgjz6f9	76	3	large	large	JJ
cord-273487-nfgjz6f9	76	4	decrease	decrease	NN
cord-273487-nfgjz6f9	76	5	(	(	-LRB-
cord-273487-nfgjz6f9	76	6	4	4	CD
cord-273487-nfgjz6f9	76	7	100-fold	100-fold	CD
cord-273487-nfgjz6f9	76	8	)	)	-RRB-
cord-273487-nfgjz6f9	76	9	in	in	IN
cord-273487-nfgjz6f9	76	10	viral	viral	JJ
cord-273487-nfgjz6f9	76	11	titers	titer	NNS
cord-273487-nfgjz6f9	76	12	,	,	,
cord-273487-nfgjz6f9	76	13	expression	expression	NN
cord-273487-nfgjz6f9	76	14	of	of	IN
cord-273487-nfgjz6f9	76	15	DEAD	dead	JJ
cord-273487-nfgjz6f9	76	16	box	box	NN
cord-273487-nfgjz6f9	76	17	mutants	mutant	NNS
cord-273487-nfgjz6f9	76	18	did	do	VBD
cord-273487-nfgjz6f9	76	19	not	not	RB
cord-273487-nfgjz6f9	76	20	interfere	interfere	VB
cord-273487-nfgjz6f9	76	21	with	with	IN
cord-273487-nfgjz6f9	76	22	replication	replication	NN
cord-273487-nfgjz6f9	76	23	of	of	IN
cord-273487-nfgjz6f9	76	24	WNV	WNV	NNP
cord-273487-nfgjz6f9	76	25	.	.	.
cord-273487-nfgjz6f9	77	1	This	this	DT
cord-273487-nfgjz6f9	77	2	conclusion	conclusion	NN
cord-273487-nfgjz6f9	77	3	is	be	VBZ
cord-273487-nfgjz6f9	77	4	based	base	VBN
cord-273487-nfgjz6f9	77	5	on	on	IN
cord-273487-nfgjz6f9	77	6	the	the	DT
cord-273487-nfgjz6f9	77	7	observation	observation	NN
cord-273487-nfgjz6f9	77	8	that	that	IN
cord-273487-nfgjz6f9	77	9	levels	level	NNS
cord-273487-nfgjz6f9	77	10	of	of	IN
cord-273487-nfgjz6f9	77	11	WNV	WNV	NNP
cord-273487-nfgjz6f9	77	12	capsid	capsid	NN
cord-273487-nfgjz6f9	77	13	protein	protein	NN
cord-273487-nfgjz6f9	77	14	were	be	VBD
cord-273487-nfgjz6f9	77	15	normal	normal	JJ
cord-273487-nfgjz6f9	77	16	in	in	IN
cord-273487-nfgjz6f9	77	17	these	these	DT
cord-273487-nfgjz6f9	77	18	cells	cell	NNS
cord-273487-nfgjz6f9	77	19	(	(	-LRB-
cord-273487-nfgjz6f9	77	20	Fig	Fig	NNP
cord-273487-nfgjz6f9	77	21	.	.	.
cord-273487-nfgjz6f9	77	22	4A	4a	CD
cord-273487-nfgjz6f9	77	23	)	)	-RRB-
cord-273487-nfgjz6f9	77	24	.	.	.
cord-273487-nfgjz6f9	78	1	The	the	DT
cord-273487-nfgjz6f9	78	2	stable	stable	JJ
cord-273487-nfgjz6f9	78	3	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	78	4	T	t	NN
cord-273487-nfgjz6f9	78	5	cell	cell	NN
cord-273487-nfgjz6f9	78	6	lines	line	NNS
cord-273487-nfgjz6f9	78	7	were	be	VBD
cord-273487-nfgjz6f9	78	8	transduced	transduce	VBN
cord-273487-nfgjz6f9	78	9	with	with	IN
cord-273487-nfgjz6f9	78	10	lentiviruses	lentiviruse	NNS
cord-273487-nfgjz6f9	78	11	encoding	encode	VBG
cord-273487-nfgjz6f9	78	12	normal	normal	JJ
cord-273487-nfgjz6f9	78	13	(	(	-LRB-
cord-273487-nfgjz6f9	78	14	RNAi	rnai	NN
cord-273487-nfgjz6f9	78	15	-	-	HYPH
cord-273487-nfgjz6f9	78	16	sensitive	sensitive	JJ
cord-273487-nfgjz6f9	78	17	)	)	-RRB-
cord-273487-nfgjz6f9	78	18	or	or	CC
cord-273487-nfgjz6f9	78	19	RNAi	rnai	NN
cord-273487-nfgjz6f9	78	20	-	-	HYPH
cord-273487-nfgjz6f9	78	21	resistant	resistant	JJ
cord-273487-nfgjz6f9	78	22	versions	version	NNS
cord-273487-nfgjz6f9	78	23	of	of	IN
cord-273487-nfgjz6f9	78	24	myc	myc	NNP
cord-273487-nfgjz6f9	78	25	-	-	HYPH
cord-273487-nfgjz6f9	78	26	tagged	tagged	NNP
cord-273487-nfgjz6f9	78	27	WT	WT	NNP
cord-273487-nfgjz6f9	78	28	and	and	CC
cord-273487-nfgjz6f9	78	29	D166N	D166N	NNP
cord-273487-nfgjz6f9	78	30	and	and	CC
cord-273487-nfgjz6f9	78	31	E167Q	e167q	NN
cord-273487-nfgjz6f9	78	32	mutants	mutant	NNS
cord-273487-nfgjz6f9	78	33	.	.	.
cord-273487-nfgjz6f9	79	1	The	the	DT
cord-273487-nfgjz6f9	79	2	lentiviruses	lentiviruse	NNS
cord-273487-nfgjz6f9	79	3	also	also	RB
cord-273487-nfgjz6f9	79	4	encode	encode	VBP
cord-273487-nfgjz6f9	79	5	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	79	6	,	,	,
cord-273487-nfgjz6f9	79	7	which	which	WDT
cord-273487-nfgjz6f9	79	8	is	be	VBZ
cord-273487-nfgjz6f9	79	9	used	use	VBN
cord-273487-nfgjz6f9	79	10	to	to	TO
cord-273487-nfgjz6f9	79	11	monitor	monitor	VB
cord-273487-nfgjz6f9	79	12	transduction	transduction	NN
cord-273487-nfgjz6f9	79	13	of	of	IN
cord-273487-nfgjz6f9	79	14	cells	cell	NNS
cord-273487-nfgjz6f9	79	15	.	.	.
cord-273487-nfgjz6f9	80	1	Forty	forty	CD
cord-273487-nfgjz6f9	80	2	-	-	HYPH
cord-273487-nfgjz6f9	80	3	eight	eight	CD
cord-273487-nfgjz6f9	80	4	hours	hour	NNS
cord-273487-nfgjz6f9	80	5	post	post	NN
cord-273487-nfgjz6f9	80	6	-	-	NN
cord-273487-nfgjz6f9	80	7	transduction	transduction	JJ
cord-273487-nfgjz6f9	80	8	,	,	,
cord-273487-nfgjz6f9	80	9	levels	level	NNS
cord-273487-nfgjz6f9	80	10	of	of	IN
cord-273487-nfgjz6f9	80	11	endogenous	endogenous	JJ
cord-273487-nfgjz6f9	80	12	and	and	CC
cord-273487-nfgjz6f9	80	13	myc	myc	NNP
cord-273487-nfgjz6f9	80	14	-	-	HYPH
cord-273487-nfgjz6f9	80	15	tagged	tag	VBN
cord-273487-nfgjz6f9	81	1	DDX56	ddx56	DT
cord-273487-nfgjz6f9	81	2	proteins	protein	NNS
cord-273487-nfgjz6f9	81	3	were	be	VBD
cord-273487-nfgjz6f9	81	4	determined	determine	VBN
cord-273487-nfgjz6f9	81	5	by	by	IN
cord-273487-nfgjz6f9	81	6	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	81	7	.	.	.
cord-273487-nfgjz6f9	82	1	Fig	Fig	NNP
cord-273487-nfgjz6f9	82	2	.	.	.
cord-273487-nfgjz6f9	83	1	3	3	LS
cord-273487-nfgjz6f9	83	2	.	.	.
cord-273487-nfgjz6f9	84	1	Mutations	mutation	NNS
cord-273487-nfgjz6f9	84	2	in	in	IN
cord-273487-nfgjz6f9	84	3	the	the	DT
cord-273487-nfgjz6f9	84	4	DEAD	dead	JJ
cord-273487-nfgjz6f9	84	5	box	box	NN
cord-273487-nfgjz6f9	84	6	active	active	JJ
cord-273487-nfgjz6f9	84	7	site	site	NN
cord-273487-nfgjz6f9	84	8	of	of	IN
cord-273487-nfgjz6f9	84	9	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	84	10	do	do	VBP
cord-273487-nfgjz6f9	84	11	not	not	RB
cord-273487-nfgjz6f9	84	12	affect	affect	VB
cord-273487-nfgjz6f9	84	13	targeting	target	VBG
cord-273487-nfgjz6f9	84	14	to	to	IN
cord-273487-nfgjz6f9	84	15	the	the	DT
cord-273487-nfgjz6f9	84	16	nucleolus	nucleolus	NN
cord-273487-nfgjz6f9	84	17	.	.	.
cord-273487-nfgjz6f9	85	1	A549	a549	JJ
cord-273487-nfgjz6f9	85	2	cells	cell	NNS
cord-273487-nfgjz6f9	85	3	were	be	VBD
cord-273487-nfgjz6f9	85	4	transfected	transfecte	VBN
cord-273487-nfgjz6f9	85	5	with	with	IN
cord-273487-nfgjz6f9	85	6	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	85	7	encoding	encode	VBG
cord-273487-nfgjz6f9	85	8	myc	myc	NNP
cord-273487-nfgjz6f9	85	9	-	-	HYPH
cord-273487-nfgjz6f9	85	10	tagged	tag	VBN
cord-273487-nfgjz6f9	85	11	wild	wild	JJ
cord-273487-nfgjz6f9	85	12	type	type	NN
cord-273487-nfgjz6f9	85	13	(	(	-LRB-
cord-273487-nfgjz6f9	85	14	WT	WT	NNP
cord-273487-nfgjz6f9	85	15	)	)	-RRB-
cord-273487-nfgjz6f9	85	16	,	,	,
cord-273487-nfgjz6f9	85	17	D166N	D166N	NNP
cord-273487-nfgjz6f9	85	18	,	,	,
cord-273487-nfgjz6f9	85	19	and	and	CC
cord-273487-nfgjz6f9	85	20	E167Q	E167Q	JJS
cord-273487-nfgjz6f9	85	21	mutants	mutant	NNS
cord-273487-nfgjz6f9	85	22	as	as	RB
cord-273487-nfgjz6f9	85	23	well	well	RB
cord-273487-nfgjz6f9	85	24	as	as	IN
cord-273487-nfgjz6f9	85	25	a	a	DT
cord-273487-nfgjz6f9	85	26	vector	vector	NN
cord-273487-nfgjz6f9	85	27	.	.	.
cord-273487-nfgjz6f9	86	1	Twenty	twenty	CD
cord-273487-nfgjz6f9	86	2	-	-	HYPH
cord-273487-nfgjz6f9	86	3	four	four	CD
cord-273487-nfgjz6f9	86	4	hours	hour	NNS
cord-273487-nfgjz6f9	86	5	post	post	NN
cord-273487-nfgjz6f9	86	6	-	-	NN
cord-273487-nfgjz6f9	86	7	transfection	transfection	JJ
cord-273487-nfgjz6f9	86	8	,	,	,
cord-273487-nfgjz6f9	86	9	cells	cell	NNS
cord-273487-nfgjz6f9	86	10	were	be	VBD
cord-273487-nfgjz6f9	86	11	infected	infect	VBN
cord-273487-nfgjz6f9	86	12	with	with	IN
cord-273487-nfgjz6f9	86	13	WNV	WNV	NNP
cord-273487-nfgjz6f9	86	14	(	(	-LRB-
cord-273487-nfgjz6f9	86	15	MOI	MOI	NNP
cord-273487-nfgjz6f9	86	16	¼5	¼5	NNP
cord-273487-nfgjz6f9	86	17	)	)	-RRB-
cord-273487-nfgjz6f9	86	18	for	for	IN
cord-273487-nfgjz6f9	86	19	24	24	CD
cord-273487-nfgjz6f9	86	20	h	h	NN
cord-273487-nfgjz6f9	86	21	and	and	CC
cord-273487-nfgjz6f9	86	22	then	then	RB
cord-273487-nfgjz6f9	86	23	fixed	fix	VBN
cord-273487-nfgjz6f9	86	24	and	and	CC
cord-273487-nfgjz6f9	86	25	processed	process	VBN
cord-273487-nfgjz6f9	86	26	for	for	IN
cord-273487-nfgjz6f9	86	27	indirect	indirect	JJ
cord-273487-nfgjz6f9	86	28	immunofluorescence	immunofluorescence	NN
cord-273487-nfgjz6f9	86	29	using	use	VBG
cord-273487-nfgjz6f9	86	30	mouse	mouse	NN
cord-273487-nfgjz6f9	86	31	anti	anti	NNP
cord-273487-nfgjz6f9	86	32	-	-	NNP
cord-273487-nfgjz6f9	86	33	myc	myc	JJ
cord-273487-nfgjz6f9	86	34	,	,	,
cord-273487-nfgjz6f9	86	35	rabbit	rabbit	NN
cord-273487-nfgjz6f9	86	36	anti	anti	NNP
cord-273487-nfgjz6f9	86	37	-	-	JJ
cord-273487-nfgjz6f9	86	38	nucleolin	nucleolin	JJ
cord-273487-nfgjz6f9	86	39	,	,	,
cord-273487-nfgjz6f9	86	40	and	and	CC
cord-273487-nfgjz6f9	86	41	guinea	guinea	NNP
cord-273487-nfgjz6f9	86	42	pig	pig	NNP
cord-273487-nfgjz6f9	86	43	anti	anti	NNP
cord-273487-nfgjz6f9	86	44	-	-	NNP
cord-273487-nfgjz6f9	86	45	WNV	WNV	NNP
cord-273487-nfgjz6f9	86	46	capsid	capsid	NN
cord-273487-nfgjz6f9	86	47	antibodies	antibody	NNS
cord-273487-nfgjz6f9	86	48	.	.	.
cord-273487-nfgjz6f9	87	1	Primary	primary	JJ
cord-273487-nfgjz6f9	87	2	antibodies	antibody	NNS
cord-273487-nfgjz6f9	87	3	were	be	VBD
cord-273487-nfgjz6f9	87	4	detected	detect	VBN
cord-273487-nfgjz6f9	87	5	using	use	VBG
cord-273487-nfgjz6f9	87	6	donkey	donkey	NN
cord-273487-nfgjz6f9	87	7	anti	anti	JJ
cord-273487-nfgjz6f9	87	8	-	-	JJ
cord-273487-nfgjz6f9	87	9	mouse	mouse	NN
cord-273487-nfgjz6f9	87	10	Alexa546	Alexa546	NNP
cord-273487-nfgjz6f9	87	11	,	,	,
cord-273487-nfgjz6f9	87	12	donkey	donkey	JJ
cord-273487-nfgjz6f9	87	13	anti	anti	JJ
cord-273487-nfgjz6f9	87	14	-	-	JJ
cord-273487-nfgjz6f9	87	15	rabbit	rabbit	NN
cord-273487-nfgjz6f9	87	16	Alexa647	Alexa647	NNP
cord-273487-nfgjz6f9	87	17	and	and	CC
cord-273487-nfgjz6f9	87	18	goat	goat	NNP
cord-273487-nfgjz6f9	87	19	anti	anti	JJ
cord-273487-nfgjz6f9	87	20	-	-	JJ
cord-273487-nfgjz6f9	87	21	guinea	guinea	JJ
cord-273487-nfgjz6f9	87	22	pig	pig	NN
cord-273487-nfgjz6f9	87	23	Alexa488	Alexa488	NNP
cord-273487-nfgjz6f9	87	24	secondary	secondary	JJ
cord-273487-nfgjz6f9	87	25	antibodies	antibody	NNS
cord-273487-nfgjz6f9	87	26	.	.	.
cord-273487-nfgjz6f9	88	1	Arrowheads	arrowhead	NNS
cord-273487-nfgjz6f9	88	2	indicate	indicate	VBP
cord-273487-nfgjz6f9	88	3	colocalization	colocalization	NN
cord-273487-nfgjz6f9	88	4	between	between	IN
cord-273487-nfgjz6f9	88	5	capsid	capsid	NN
cord-273487-nfgjz6f9	88	6	,	,	,
cord-273487-nfgjz6f9	88	7	DDX56	ddx56	DT
cord-273487-nfgjz6f9	88	8	proteins	protein	NNS
cord-273487-nfgjz6f9	88	9	and	and	CC
cord-273487-nfgjz6f9	88	10	the	the	DT
cord-273487-nfgjz6f9	88	11	nucleolar	nucleolar	JJ
cord-273487-nfgjz6f9	88	12	resident	resident	NN
cord-273487-nfgjz6f9	88	13	protein	protein	NN
cord-273487-nfgjz6f9	88	14	nucleolin	nucleolin	NNP
cord-273487-nfgjz6f9	88	15	.	.	.
cord-273487-nfgjz6f9	89	1	Nuclei	nucleus	NNS
cord-273487-nfgjz6f9	89	2	were	be	VBD
cord-273487-nfgjz6f9	89	3	stained	stain	VBN
cord-273487-nfgjz6f9	89	4	with	with	IN
cord-273487-nfgjz6f9	89	5	DAPI	DAPI	NNP
cord-273487-nfgjz6f9	89	6	.	.	.
cord-273487-nfgjz6f9	90	1	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	90	2	-	-	HYPH
cord-273487-nfgjz6f9	90	3	sensitive	sensitive	JJ
cord-273487-nfgjz6f9	90	4	(	(	-LRB-
cord-273487-nfgjz6f9	90	5	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	90	6	-	-	HYPH
cord-273487-nfgjz6f9	90	7	S	S	NNP
cord-273487-nfgjz6f9	90	8	)	)	-RRB-
cord-273487-nfgjz6f9	90	9	and	and	CC
cord-273487-nfgjz6f9	90	10	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	90	11	-	-	HYPH
cord-273487-nfgjz6f9	90	12	resistant	resistant	JJ
cord-273487-nfgjz6f9	90	13	(	(	-LRB-
cord-273487-nfgjz6f9	90	14	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	90	15	-	-	HYPH
cord-273487-nfgjz6f9	90	16	R	R	NNP
cord-273487-nfgjz6f9	90	17	)	)	-RRB-
cord-273487-nfgjz6f9	90	18	forms	form	NNS
cord-273487-nfgjz6f9	90	19	of	of	IN
cord-273487-nfgjz6f9	90	20	WT	wt	NN
cord-273487-nfgjz6f9	90	21	and	and	CC
cord-273487-nfgjz6f9	91	1	DDX56	ddx56	DT
cord-273487-nfgjz6f9	91	2	mutants	mutant	NNS
cord-273487-nfgjz6f9	91	3	are	be	VBP
cord-273487-nfgjz6f9	91	4	indicated	indicate	VBN
cord-273487-nfgjz6f9	91	5	.	.	.
cord-273487-nfgjz6f9	92	1	Images	image	NNS
cord-273487-nfgjz6f9	92	2	were	be	VBD
cord-273487-nfgjz6f9	92	3	captured	capture	VBN
cord-273487-nfgjz6f9	92	4	using	use	VBG
cord-273487-nfgjz6f9	92	5	a	a	DT
cord-273487-nfgjz6f9	92	6	leica	leica	NNP
cord-273487-nfgjz6f9	92	7	TCS	TCS	NNP
cord-273487-nfgjz6f9	92	8	SP5	SP5	NNP
cord-273487-nfgjz6f9	92	9	confocal	confocal	JJ
cord-273487-nfgjz6f9	92	10	scanning	scanning	NN
cord-273487-nfgjz6f9	92	11	microscope	microscope	NN
cord-273487-nfgjz6f9	92	12	.	.	.
cord-273487-nfgjz6f9	93	1	Size	size	NN
cord-273487-nfgjz6f9	93	2	bar	bar	NN
cord-273487-nfgjz6f9	93	3	¼10	¼10	NN
cord-273487-nfgjz6f9	93	4	mm	mm	NN
cord-273487-nfgjz6f9	93	5	.	.	.
cord-273487-nfgjz6f9	94	1	Our	-PRON-	PRP$
cord-273487-nfgjz6f9	94	2	recent	recent	JJ
cord-273487-nfgjz6f9	94	3	studies	study	NNS
cord-273487-nfgjz6f9	94	4	suggest	suggest	VBP
cord-273487-nfgjz6f9	94	5	that	that	IN
cord-273487-nfgjz6f9	94	6	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	94	7	may	may	MD
cord-273487-nfgjz6f9	94	8	function	function	VB
cord-273487-nfgjz6f9	94	9	in	in	IN
cord-273487-nfgjz6f9	94	10	packaging	package	VBG
cord-273487-nfgjz6f9	94	11	viral	viral	JJ
cord-273487-nfgjz6f9	94	12	genomic	genomic	JJ
cord-273487-nfgjz6f9	94	13	RNA	RNA	NNP
cord-273487-nfgjz6f9	94	14	into	into	IN
cord-273487-nfgjz6f9	94	15	nascent	nascent	JJ
cord-273487-nfgjz6f9	94	16	virions	virion	NNS
cord-273487-nfgjz6f9	94	17	(	(	-LRB-
cord-273487-nfgjz6f9	94	18	Xu	Xu	NNP
cord-273487-nfgjz6f9	94	19	et	et	NNP
cord-273487-nfgjz6f9	94	20	al	al	NNP
cord-273487-nfgjz6f9	94	21	.	.	NNP
cord-273487-nfgjz6f9	94	22	,	,	,
cord-273487-nfgjz6f9	94	23	2011	2011	CD
cord-273487-nfgjz6f9	94	24	)	)	-RRB-
cord-273487-nfgjz6f9	94	25	.	.	.
cord-273487-nfgjz6f9	95	1	To	to	TO
cord-273487-nfgjz6f9	95	2	establish	establish	VB
cord-273487-nfgjz6f9	95	3	whether	whether	IN
cord-273487-nfgjz6f9	95	4	the	the	DT
cord-273487-nfgjz6f9	95	5	helicase	helicase	NN
cord-273487-nfgjz6f9	95	6	activity	activity	NN
cord-273487-nfgjz6f9	95	7	of	of	IN
cord-273487-nfgjz6f9	95	8	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	95	9	is	be	VBZ
cord-273487-nfgjz6f9	95	10	important	important	JJ
cord-273487-nfgjz6f9	95	11	for	for	IN
cord-273487-nfgjz6f9	95	12	this	this	DT
cord-273487-nfgjz6f9	95	13	process	process	NN
cord-273487-nfgjz6f9	95	14	,	,	,
cord-273487-nfgjz6f9	95	15	we	-PRON-	PRP
cord-273487-nfgjz6f9	95	16	assayed	assay	VBD
cord-273487-nfgjz6f9	95	17	the	the	DT
cord-273487-nfgjz6f9	95	18	relative	relative	JJ
cord-273487-nfgjz6f9	95	19	amounts	amount	NNS
cord-273487-nfgjz6f9	95	20	of	of	IN
cord-273487-nfgjz6f9	95	21	genomic	genomic	JJ
cord-273487-nfgjz6f9	95	22	RNA	RNA	NNP
cord-273487-nfgjz6f9	95	23	in	in	IN
cord-273487-nfgjz6f9	95	24	WNV	WNV	NNP
cord-273487-nfgjz6f9	95	25	particles	particle	NNS
cord-273487-nfgjz6f9	95	26	secreted	secrete	VBN
cord-273487-nfgjz6f9	95	27	from	from	IN
cord-273487-nfgjz6f9	95	28	cells	cell	NNS
cord-273487-nfgjz6f9	95	29	expressing	express	VBG
cord-273487-nfgjz6f9	95	30	D166N	D166N	NNP
cord-273487-nfgjz6f9	95	31	and	and	CC
cord-273487-nfgjz6f9	95	32	E167Q	e167q	NN
cord-273487-nfgjz6f9	95	33	mutants	mutant	NNS
cord-273487-nfgjz6f9	95	34	.	.	.
cord-273487-nfgjz6f9	96	1	Loss	loss	NN
cord-273487-nfgjz6f9	96	2	of	of	IN
cord-273487-nfgjz6f9	96	3	DDX56	ddx56	DT
cord-273487-nfgjz6f9	96	4	helicase	helicase	NN
cord-273487-nfgjz6f9	96	5	activity	activity	NN
cord-273487-nfgjz6f9	96	6	did	do	VBD
cord-273487-nfgjz6f9	96	7	not	not	RB
cord-273487-nfgjz6f9	96	8	affect	affect	VB
cord-273487-nfgjz6f9	96	9	expression	expression	NN
cord-273487-nfgjz6f9	96	10	of	of	IN
cord-273487-nfgjz6f9	96	11	WNV	WNV	NNP
cord-273487-nfgjz6f9	96	12	capsid	capsid	NN
cord-273487-nfgjz6f9	96	13	protein	protein	NN
cord-273487-nfgjz6f9	96	14	(	(	-LRB-
cord-273487-nfgjz6f9	96	15	Fig	Fig	NNP
cord-273487-nfgjz6f9	96	16	.	.	.
cord-273487-nfgjz6f9	96	17	4A	4a	LS
cord-273487-nfgjz6f9	96	18	)	)	-RRB-
cord-273487-nfgjz6f9	96	19	nor	nor	CC
cord-273487-nfgjz6f9	96	20	its	-PRON-	PRP$
cord-273487-nfgjz6f9	96	21	secretion	secretion	NN
cord-273487-nfgjz6f9	96	22	from	from	IN
cord-273487-nfgjz6f9	96	23	infected	infected	JJ
cord-273487-nfgjz6f9	96	24	cells	cell	NNS
cord-273487-nfgjz6f9	96	25	in	in	IN
cord-273487-nfgjz6f9	96	26	the	the	DT
cord-273487-nfgjz6f9	96	27	form	form	NN
cord-273487-nfgjz6f9	96	28	of	of	IN
cord-273487-nfgjz6f9	96	29	virus	virus	NN
cord-273487-nfgjz6f9	96	30	particles	particle	NNS
cord-273487-nfgjz6f9	96	31	(	(	-LRB-
cord-273487-nfgjz6f9	96	32	Fig	Fig	NNP
cord-273487-nfgjz6f9	96	33	.	.	.
cord-273487-nfgjz6f9	96	34	5A	5a	CD
cord-273487-nfgjz6f9	96	35	)	)	-RRB-
cord-273487-nfgjz6f9	96	36	.	.	.
cord-273487-nfgjz6f9	97	1	To	to	TO
cord-273487-nfgjz6f9	97	2	determine	determine	VB
cord-273487-nfgjz6f9	97	3	if	if	IN
cord-273487-nfgjz6f9	97	4	packaging	packaging	NN
cord-273487-nfgjz6f9	97	5	of	of	IN
cord-273487-nfgjz6f9	97	6	viral	viral	JJ
cord-273487-nfgjz6f9	97	7	RNA	RNA	NNP
cord-273487-nfgjz6f9	97	8	was	be	VBD
cord-273487-nfgjz6f9	97	9	affected	affect	VBN
cord-273487-nfgjz6f9	97	10	,	,	,
cord-273487-nfgjz6f9	97	11	total	total	JJ
cord-273487-nfgjz6f9	97	12	RNA	RNA	NNP
cord-273487-nfgjz6f9	97	13	was	be	VBD
cord-273487-nfgjz6f9	97	14	extracted	extract	VBN
cord-273487-nfgjz6f9	97	15	from	from	IN
cord-273487-nfgjz6f9	97	16	WNV	WNV	NNP
cord-273487-nfgjz6f9	97	17	particles	particle	NNS
cord-273487-nfgjz6f9	97	18	and	and	CC
cord-273487-nfgjz6f9	97	19	the	the	DT
cord-273487-nfgjz6f9	97	20	relative	relative	JJ
cord-273487-nfgjz6f9	97	21	amounts	amount	NNS
cord-273487-nfgjz6f9	97	22	of	of	IN
cord-273487-nfgjz6f9	97	23	genomic	genomic	JJ
cord-273487-nfgjz6f9	97	24	RNA	RNA	NNP
cord-273487-nfgjz6f9	97	25	(	(	-LRB-
cord-273487-nfgjz6f9	97	26	normalized	normalize	VBN
cord-273487-nfgjz6f9	97	27	to	to	IN
cord-273487-nfgjz6f9	97	28	capsid	capsid	NN
cord-273487-nfgjz6f9	97	29	protein	protein	NN
cord-273487-nfgjz6f9	97	30	)	)	-RRB-
cord-273487-nfgjz6f9	97	31	were	be	VBD
cord-273487-nfgjz6f9	97	32	determined	determine	VBN
cord-273487-nfgjz6f9	97	33	by	by	IN
cord-273487-nfgjz6f9	97	34	RT	RT	NNP
cord-273487-nfgjz6f9	97	35	-	-	HYPH
cord-273487-nfgjz6f9	97	36	PCR	PCR	NNP
cord-273487-nfgjz6f9	97	37	.	.	.
cord-273487-nfgjz6f9	98	1	Data	datum	NNS
cord-273487-nfgjz6f9	98	2	in	in	IN
cord-273487-nfgjz6f9	98	3	Fig	Fig	NNP
cord-273487-nfgjz6f9	98	4	.	.	.
cord-273487-nfgjz6f9	99	1	5B	5B	NNP
cord-273487-nfgjz6f9	99	2	show	show	VBP
cord-273487-nfgjz6f9	99	3	that	that	IN
cord-273487-nfgjz6f9	99	4	virus	virus	NN
cord-273487-nfgjz6f9	99	5	particles	particle	NNS
cord-273487-nfgjz6f9	99	6	isolated	isolate	VBN
cord-273487-nfgjz6f9	99	7	from	from	IN
cord-273487-nfgjz6f9	99	8	infected	infected	JJ
cord-273487-nfgjz6f9	99	9	cells	cell	NNS
cord-273487-nfgjz6f9	99	10	expressing	express	VBG
cord-273487-nfgjz6f9	99	11	helicase	helicase	NN
cord-273487-nfgjz6f9	99	12	dead	dead	JJ
cord-273487-nfgjz6f9	99	13	mutants	mutant	NNS
cord-273487-nfgjz6f9	99	14	D166N	D166N	NNPS
cord-273487-nfgjz6f9	99	15	and	and	CC
cord-273487-nfgjz6f9	99	16	E167Q	E167Q	NNP
cord-273487-nfgjz6f9	99	17	contained	contain	VBN
cord-273487-nfgjz6f9	99	18	3	3	CD
cord-273487-nfgjz6f9	99	19	-	-	SYM
cord-273487-nfgjz6f9	99	20	4	4	CD
cord-273487-nfgjz6f9	99	21	times	time	NNS
cord-273487-nfgjz6f9	99	22	less	less	RBR
cord-273487-nfgjz6f9	99	23	genomic	genomic	JJ
cord-273487-nfgjz6f9	99	24	RNA	RNA	NNP
cord-273487-nfgjz6f9	99	25	than	than	IN
cord-273487-nfgjz6f9	99	26	those	those	DT
cord-273487-nfgjz6f9	99	27	isolated	isolate	VBN
cord-273487-nfgjz6f9	99	28	from	from	IN
cord-273487-nfgjz6f9	99	29	non	non	JJ
cord-273487-nfgjz6f9	99	30	-	-	JJ
cord-273487-nfgjz6f9	99	31	silencing	silencing	JJ
cord-273487-nfgjz6f9	99	32	cells	cell	NNS
cord-273487-nfgjz6f9	99	33	or	or	CC
cord-273487-nfgjz6f9	99	34	cells	cell	NNS
cord-273487-nfgjz6f9	99	35	expressing	express	VBG
cord-273487-nfgjz6f9	99	36	RNAi	rnai	NN
cord-273487-nfgjz6f9	99	37	-	-	HYPH
cord-273487-nfgjz6f9	99	38	resistant	resistant	JJ
cord-273487-nfgjz6f9	99	39	wild	wild	JJ
cord-273487-nfgjz6f9	99	40	type	type	NN
cord-273487-nfgjz6f9	99	41	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	99	42	.	.	.
cord-273487-nfgjz6f9	100	1	These	these	DT
cord-273487-nfgjz6f9	100	2	data	datum	NNS
cord-273487-nfgjz6f9	100	3	indicate	indicate	VBP
cord-273487-nfgjz6f9	100	4	that	that	IN
cord-273487-nfgjz6f9	100	5	the	the	DT
cord-273487-nfgjz6f9	100	6	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	100	7	activity	activity	NN
cord-273487-nfgjz6f9	100	8	of	of	IN
cord-273487-nfgjz6f9	100	9	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	100	10	is	be	VBZ
cord-273487-nfgjz6f9	100	11	important	important	JJ
cord-273487-nfgjz6f9	100	12	for	for	IN
cord-273487-nfgjz6f9	100	13	packaging	package	VBG
cord-273487-nfgjz6f9	100	14	genomic	genomic	JJ
cord-273487-nfgjz6f9	100	15	RNA	RNA	NNP
cord-273487-nfgjz6f9	100	16	into	into	IN
cord-273487-nfgjz6f9	100	17	WNV	WNV	NNP
cord-273487-nfgjz6f9	100	18	virions	virion	NNS
cord-273487-nfgjz6f9	100	19	.	.	.
cord-273487-nfgjz6f9	101	1	Over	over	IN
cord-273487-nfgjz6f9	101	2	-	-	HYPH
cord-273487-nfgjz6f9	101	3	expression	expression	NN
cord-273487-nfgjz6f9	101	4	of	of	IN
cord-273487-nfgjz6f9	101	5	the	the	DT
cord-273487-nfgjz6f9	101	6	capsid	capsid	RB
cord-273487-nfgjz6f9	101	7	-	-	HYPH
cord-273487-nfgjz6f9	101	8	binding	bind	VBG
cord-273487-nfgjz6f9	101	9	region	region	NN
cord-273487-nfgjz6f9	101	10	of	of	IN
cord-273487-nfgjz6f9	101	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	101	12	reduces	reduce	VBZ
cord-273487-nfgjz6f9	101	13	infectivity	infectivity	NN
cord-273487-nfgjz6f9	101	14	of	of	IN
cord-273487-nfgjz6f9	101	15	WNV	WNV	NNP
cord-273487-nfgjz6f9	102	1	The	the	DT
cord-273487-nfgjz6f9	102	2	data	datum	NNS
cord-273487-nfgjz6f9	102	3	shown	show	VBN
cord-273487-nfgjz6f9	102	4	above	above	IN
cord-273487-nfgjz6f9	102	5	together	together	RB
cord-273487-nfgjz6f9	102	6	with	with	IN
cord-273487-nfgjz6f9	102	7	results	result	NNS
cord-273487-nfgjz6f9	102	8	from	from	IN
cord-273487-nfgjz6f9	102	9	our	-PRON-	PRP$
cord-273487-nfgjz6f9	102	10	previous	previous	JJ
cord-273487-nfgjz6f9	102	11	study	study	NN
cord-273487-nfgjz6f9	102	12	(	(	-LRB-
cord-273487-nfgjz6f9	102	13	Xu	Xu	NNP
cord-273487-nfgjz6f9	102	14	et	et	NNP
cord-273487-nfgjz6f9	102	15	al	al	NNP
cord-273487-nfgjz6f9	102	16	.	.	NNP
cord-273487-nfgjz6f9	102	17	,	,	,
cord-273487-nfgjz6f9	102	18	2011	2011	CD
cord-273487-nfgjz6f9	102	19	)	)	-RRB-
cord-273487-nfgjz6f9	102	20	are	be	VBP
cord-273487-nfgjz6f9	102	21	consistent	consistent	JJ
cord-273487-nfgjz6f9	102	22	with	with	IN
cord-273487-nfgjz6f9	102	23	a	a	DT
cord-273487-nfgjz6f9	102	24	scenario	scenario	NN
cord-273487-nfgjz6f9	102	25	in	in	IN
cord-273487-nfgjz6f9	102	26	which	which	WDT
cord-273487-nfgjz6f9	102	27	interaction	interaction	NN
cord-273487-nfgjz6f9	102	28	between	between	IN
cord-273487-nfgjz6f9	102	29	WNV	WNV	NNP
cord-273487-nfgjz6f9	102	30	and	and	CC
cord-273487-nfgjz6f9	102	31	catalytically	catalytically	RB
cord-273487-nfgjz6f9	102	32	active	active	JJ
cord-273487-nfgjz6f9	102	33	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	102	34	plays	play	VBZ
cord-273487-nfgjz6f9	102	35	an	an	DT
cord-273487-nfgjz6f9	102	36	important	important	JJ
cord-273487-nfgjz6f9	102	37	role	role	NN
cord-273487-nfgjz6f9	102	38	in	in	IN
cord-273487-nfgjz6f9	102	39	assembly	assembly	NN
cord-273487-nfgjz6f9	102	40	of	of	IN
cord-273487-nfgjz6f9	102	41	infectious	infectious	JJ
cord-273487-nfgjz6f9	102	42	virions	virion	NNS
cord-273487-nfgjz6f9	102	43	.	.	.
cord-273487-nfgjz6f9	103	1	If	if	IN
cord-273487-nfgjz6f9	103	2	this	this	DT
cord-273487-nfgjz6f9	103	3	is	be	VBZ
cord-273487-nfgjz6f9	103	4	indeed	indeed	RB
cord-273487-nfgjz6f9	103	5	the	the	DT
cord-273487-nfgjz6f9	103	6	case	case	NN
cord-273487-nfgjz6f9	103	7	,	,	,
cord-273487-nfgjz6f9	103	8	blocking	block	VBG
cord-273487-nfgjz6f9	103	9	interaction	interaction	NN
cord-273487-nfgjz6f9	103	10	between	between	IN
cord-273487-nfgjz6f9	103	11	capsid	capsid	NN
cord-273487-nfgjz6f9	103	12	and	and	CC
cord-273487-nfgjz6f9	103	13	DDX56	ddx56	DT
cord-273487-nfgjz6f9	103	14	should	should	MD
cord-273487-nfgjz6f9	103	15	also	also	RB
cord-273487-nfgjz6f9	103	16	reduce	reduce	VB
cord-273487-nfgjz6f9	103	17	the	the	DT
cord-273487-nfgjz6f9	103	18	yield	yield	NN
cord-273487-nfgjz6f9	103	19	of	of	IN
cord-273487-nfgjz6f9	103	20	infectious	infectious	JJ
cord-273487-nfgjz6f9	103	21	WNV	WNV	NNP
cord-273487-nfgjz6f9	103	22	.	.	.
cord-273487-nfgjz6f9	104	1	Our	-PRON-	PRP$
cord-273487-nfgjz6f9	104	2	approach	approach	NN
cord-273487-nfgjz6f9	104	3	was	be	VBD
cord-273487-nfgjz6f9	104	4	to	to	IN
cord-273487-nfgjz6f9	104	5	over	over	IN
cord-273487-nfgjz6f9	104	6	-	-	HYPH
cord-273487-nfgjz6f9	104	7	express	express	VB
cord-273487-nfgjz6f9	104	8	the	the	DT
cord-273487-nfgjz6f9	104	9	capsid	capsid	RB
cord-273487-nfgjz6f9	104	10	-	-	HYPH
cord-273487-nfgjz6f9	104	11	binding	bind	VBG
cord-273487-nfgjz6f9	104	12	region	region	NN
cord-273487-nfgjz6f9	104	13	of	of	IN
cord-273487-nfgjz6f9	104	14	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	104	15	in	in	IN
cord-273487-nfgjz6f9	104	16	order	order	NN
cord-273487-nfgjz6f9	104	17	to	to	TO
cord-273487-nfgjz6f9	104	18	prevent	prevent	VB
cord-273487-nfgjz6f9	104	19	interaction	interaction	NN
cord-273487-nfgjz6f9	104	20	of	of	IN
cord-273487-nfgjz6f9	104	21	endogenous	endogenous	JJ
cord-273487-nfgjz6f9	104	22	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	104	23	with	with	IN
cord-273487-nfgjz6f9	104	24	capsid	capsid	NN
cord-273487-nfgjz6f9	104	25	.	.	.
cord-273487-nfgjz6f9	105	1	To	to	TO
cord-273487-nfgjz6f9	105	2	identify	identify	VB
cord-273487-nfgjz6f9	105	3	the	the	DT
cord-273487-nfgjz6f9	105	4	region	region	NN
cord-273487-nfgjz6f9	105	5	of	of	IN
cord-273487-nfgjz6f9	105	6	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	105	7	that	that	WDT
cord-273487-nfgjz6f9	105	8	binds	bind	VBZ
cord-273487-nfgjz6f9	105	9	to	to	IN
cord-273487-nfgjz6f9	105	10	capsid	capsid	NN
cord-273487-nfgjz6f9	105	11	,	,	,
cord-273487-nfgjz6f9	105	12	myc	myc	NNP
cord-273487-nfgjz6f9	105	13	-	-	HYPH
cord-273487-nfgjz6f9	105	14	tagged	tag	VBN
cord-273487-nfgjz6f9	105	15	constructs	construct	NNS
cord-273487-nfgjz6f9	105	16	encoding	encode	VBG
cord-273487-nfgjz6f9	105	17	the	the	DT
cord-273487-nfgjz6f9	105	18	N	N	NNP
cord-273487-nfgjz6f9	105	19	-	-	HYPH
cord-273487-nfgjz6f9	105	20	and	and	CC
cord-273487-nfgjz6f9	105	21	C	c	NN
cord-273487-nfgjz6f9	105	22	-	-	HYPH
cord-273487-nfgjz6f9	105	23	terminal	terminal	NN
cord-273487-nfgjz6f9	105	24	regions	region	NNS
cord-273487-nfgjz6f9	105	25	of	of	IN
cord-273487-nfgjz6f9	105	26	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	105	27	were	be	VBD
cord-273487-nfgjz6f9	105	28	coexpressed	coexpresse	VBN
cord-273487-nfgjz6f9	105	29	with	with	IN
cord-273487-nfgjz6f9	105	30	WNV	WNV	NNP
cord-273487-nfgjz6f9	105	31	capsid	capsid	NN
cord-273487-nfgjz6f9	105	32	in	in	IN
cord-273487-nfgjz6f9	105	33	transfected	transfecte	VBN
cord-273487-nfgjz6f9	105	34	cells	cell	NNS
cord-273487-nfgjz6f9	105	35	followed	follow	VBN
cord-273487-nfgjz6f9	105	36	by	by	IN
cord-273487-nfgjz6f9	105	37	coimmunoprecipitation	coimmunoprecipitation	NN
cord-273487-nfgjz6f9	105	38	and	and	CC
cord-273487-nfgjz6f9	105	39	immunoblotting	immunoblotting	NN
cord-273487-nfgjz6f9	105	40	.	.	.
cord-273487-nfgjz6f9	106	1	Data	datum	NNS
cord-273487-nfgjz6f9	106	2	in	in	IN
cord-273487-nfgjz6f9	106	3	Fig	Fig	NNP
cord-273487-nfgjz6f9	106	4	.	.	.
cord-273487-nfgjz6f9	107	1	6	6	CD
cord-273487-nfgjz6f9	107	2	show	show	VBP
cord-273487-nfgjz6f9	107	3	that	that	IN
cord-273487-nfgjz6f9	107	4	in	in	IN
cord-273487-nfgjz6f9	107	5	transfected	transfecte	VBN
cord-273487-nfgjz6f9	107	6	or	or	CC
cord-273487-nfgjz6f9	107	7	infected	infected	JJ
cord-273487-nfgjz6f9	107	8	cells	cell	NNS
cord-273487-nfgjz6f9	107	9	,	,	,
cord-273487-nfgjz6f9	107	10	the	the	DT
cord-273487-nfgjz6f9	107	11	WNV	WNV	NNP
cord-273487-nfgjz6f9	107	12	capsid	capsid	NN
cord-273487-nfgjz6f9	107	13	does	do	VBZ
cord-273487-nfgjz6f9	107	14	not	not	RB
cord-273487-nfgjz6f9	107	15	bind	bind	VB
cord-273487-nfgjz6f9	107	16	to	to	IN
cord-273487-nfgjz6f9	107	17	the	the	DT
cord-273487-nfgjz6f9	107	18	DEAD	DEAD	NNP
cord-273487-nfgjz6f9	107	19	box	box	NN
cord-273487-nfgjz6f9	107	20	helicase	helicase	NN
cord-273487-nfgjz6f9	107	21	-	-	HYPH
cord-273487-nfgjz6f9	107	22	containing	contain	VBG
cord-273487-nfgjz6f9	107	23	region	region	NN
cord-273487-nfgjz6f9	107	24	of	of	IN
cord-273487-nfgjz6f9	107	25	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	107	26	(	(	-LRB-
cord-273487-nfgjz6f9	107	27	DDX56-NT	DDX56-NT	NNP
cord-273487-nfgjz6f9	107	28	-	-	HYPH
cord-273487-nfgjz6f9	107	29	myc	myc	NNP
cord-273487-nfgjz6f9	107	30	)	)	-RRB-
cord-273487-nfgjz6f9	107	31	,	,	,
cord-273487-nfgjz6f9	107	32	but	but	CC
cord-273487-nfgjz6f9	107	33	rather	rather	RB
cord-273487-nfgjz6f9	107	34	,	,	,
cord-273487-nfgjz6f9	107	35	the	the	DT
cord-273487-nfgjz6f9	107	36	C	C	NNP
cord-273487-nfgjz6f9	107	37	-	-	HYPH
cord-273487-nfgjz6f9	107	38	terminal	terminal	NN
cord-273487-nfgjz6f9	107	39	part	part	NN
cord-273487-nfgjz6f9	107	40	of	of	IN
cord-273487-nfgjz6f9	107	41	the	the	DT
cord-273487-nfgjz6f9	107	42	protein	protein	NN
cord-273487-nfgjz6f9	107	43	,	,	,
cord-273487-nfgjz6f9	107	44	which	which	WDT
cord-273487-nfgjz6f9	107	45	was	be	VBD
cord-273487-nfgjz6f9	107	46	produced	produce	VBN
cord-273487-nfgjz6f9	107	47	in	in	IN
cord-273487-nfgjz6f9	107	48	cells	cell	NNS
cord-273487-nfgjz6f9	107	49	expressing	express	VBG
cord-273487-nfgjz6f9	107	50	DDX56-CT	DDX56-CT	NNP
cord-273487-nfgjz6f9	107	51	-	-	HYPH
cord-273487-nfgjz6f9	107	52	myc	myc	NNP
cord-273487-nfgjz6f9	107	53	.	.	.
cord-273487-nfgjz6f9	108	1	This	this	DT
cord-273487-nfgjz6f9	108	2	region	region	NN
cord-273487-nfgjz6f9	108	3	of	of	IN
cord-273487-nfgjz6f9	108	4	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	108	5	also	also	RB
cord-273487-nfgjz6f9	108	6	contains	contain	VBZ
cord-273487-nfgjz6f9	108	7	the	the	DT
cord-273487-nfgjz6f9	108	8	targeting	target	VBG
cord-273487-nfgjz6f9	108	9	information	information	NN
cord-273487-nfgjz6f9	108	10	that	that	WDT
cord-273487-nfgjz6f9	108	11	is	be	VBZ
cord-273487-nfgjz6f9	108	12	required	require	VBN
cord-273487-nfgjz6f9	108	13	for	for	IN
cord-273487-nfgjz6f9	108	14	localization	localization	NN
cord-273487-nfgjz6f9	108	15	to	to	IN
cord-273487-nfgjz6f9	108	16	the	the	DT
cord-273487-nfgjz6f9	108	17	nucleolus	nucleolus	NN
cord-273487-nfgjz6f9	108	18	(	(	-LRB-
cord-273487-nfgjz6f9	108	19	Fig	Fig	NNP
cord-273487-nfgjz6f9	108	20	.	.	NNP
cord-273487-nfgjz6f9	108	21	7	7	CD
cord-273487-nfgjz6f9	108	22	)	)	-RRB-
cord-273487-nfgjz6f9	108	23	.	.	.
cord-273487-nfgjz6f9	109	1	Next	next	RB
cord-273487-nfgjz6f9	109	2	,	,	,
cord-273487-nfgjz6f9	109	3	lentiviruses	lentiviruses	NNP
cord-273487-nfgjz6f9	109	4	encoding	encode	VBG
cord-273487-nfgjz6f9	110	1	myc	myc	NNP
cord-273487-nfgjz6f9	110	2	-	-	HYPH
cord-273487-nfgjz6f9	110	3	tagged	tag	VBN
cord-273487-nfgjz6f9	110	4	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	110	5	N	N	NNP
cord-273487-nfgjz6f9	110	6	-	-	HYPH
cord-273487-nfgjz6f9	110	7	and	and	CC
cord-273487-nfgjz6f9	110	8	Cterminal	Cterminal	NNP
cord-273487-nfgjz6f9	110	9	regions	region	NNS
cord-273487-nfgjz6f9	110	10	were	be	VBD
cord-273487-nfgjz6f9	110	11	used	use	VBN
cord-273487-nfgjz6f9	110	12	to	to	TO
cord-273487-nfgjz6f9	110	13	transduce	transduce	VB
cord-273487-nfgjz6f9	110	14	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	110	15	T	t	NN
cord-273487-nfgjz6f9	110	16	cells	cell	NNS
cord-273487-nfgjz6f9	110	17	,	,	,
cord-273487-nfgjz6f9	110	18	which	which	WDT
cord-273487-nfgjz6f9	110	19	were	be	VBD
cord-273487-nfgjz6f9	110	20	then	then	RB
cord-273487-nfgjz6f9	110	21	infected	infect	VBN
cord-273487-nfgjz6f9	110	22	with	with	IN
cord-273487-nfgjz6f9	110	23	WNV	WNV	NNP
cord-273487-nfgjz6f9	110	24	.	.	.
cord-273487-nfgjz6f9	111	1	At	at	IN
cord-273487-nfgjz6f9	111	2	48	48	CD
cord-273487-nfgjz6f9	111	3	h	h	NN
cord-273487-nfgjz6f9	111	4	post	post	NN
cord-273487-nfgjz6f9	111	5	-	-	NN
cord-273487-nfgjz6f9	111	6	infection	infection	NN
cord-273487-nfgjz6f9	111	7	,	,	,
cord-273487-nfgjz6f9	111	8	cell	cell	NN
cord-273487-nfgjz6f9	111	9	lysates	lysate	NNS
cord-273487-nfgjz6f9	111	10	and	and	CC
cord-273487-nfgjz6f9	111	11	culture	culture	NN
cord-273487-nfgjz6f9	111	12	supernatants	supernatant	NNS
cord-273487-nfgjz6f9	111	13	were	be	VBD
cord-273487-nfgjz6f9	111	14	subjected	subject	VBN
cord-273487-nfgjz6f9	111	15	to	to	IN
cord-273487-nfgjz6f9	111	16	immunoblot	immunoblot	NNP
cord-273487-nfgjz6f9	111	17	and	and	CC
cord-273487-nfgjz6f9	111	18	plaque	plaque	NN
cord-273487-nfgjz6f9	111	19	assays	assay	NNS
cord-273487-nfgjz6f9	111	20	,	,	,
cord-273487-nfgjz6f9	111	21	respectively	respectively	RB
cord-273487-nfgjz6f9	111	22	.	.	.
cord-273487-nfgjz6f9	112	1	Data	datum	NNS
cord-273487-nfgjz6f9	112	2	in	in	IN
cord-273487-nfgjz6f9	112	3	Fig	Fig	NNP
cord-273487-nfgjz6f9	112	4	.	.	.
cord-273487-nfgjz6f9	113	1	8A	8A	NNP
cord-273487-nfgjz6f9	113	2	show	show	VBP
cord-273487-nfgjz6f9	113	3	that	that	IN
cord-273487-nfgjz6f9	113	4	expression	expression	NN
cord-273487-nfgjz6f9	113	5	of	of	IN
cord-273487-nfgjz6f9	113	6	full	full	JJ
cord-273487-nfgjz6f9	113	7	length	length	NN
cord-273487-nfgjz6f9	113	8	,	,	,
cord-273487-nfgjz6f9	113	9	N	n	CD
cord-273487-nfgjz6f9	113	10	-	-	HYPH
cord-273487-nfgjz6f9	113	11	or	or	CC
cord-273487-nfgjz6f9	113	12	C	c	NN
cord-273487-nfgjz6f9	113	13	-	-	HYPH
cord-273487-nfgjz6f9	113	14	terminal	terminal	NN
cord-273487-nfgjz6f9	113	15	regions	region	NNS
cord-273487-nfgjz6f9	113	16	of	of	IN
cord-273487-nfgjz6f9	113	17	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	113	18	do	do	VBP
cord-273487-nfgjz6f9	113	19	not	not	RB
cord-273487-nfgjz6f9	113	20	affect	affect	VB
cord-273487-nfgjz6f9	113	21	viral	viral	JJ
cord-273487-nfgjz6f9	113	22	gene	gene	NN
cord-273487-nfgjz6f9	113	23	expression	expression	NN
cord-273487-nfgjz6f9	113	24	based	base	VBN
cord-273487-nfgjz6f9	113	25	on	on	IN
cord-273487-nfgjz6f9	113	26	the	the	DT
cord-273487-nfgjz6f9	113	27	observation	observation	NN
cord-273487-nfgjz6f9	113	28	that	that	IN
cord-273487-nfgjz6f9	113	29	similar	similar	JJ
cord-273487-nfgjz6f9	113	30	levels	level	NNS
cord-273487-nfgjz6f9	113	31	of	of	IN
cord-273487-nfgjz6f9	113	32	capsid	capsid	NN
cord-273487-nfgjz6f9	113	33	protein	protein	NN
cord-273487-nfgjz6f9	113	34	were	be	VBD
cord-273487-nfgjz6f9	113	35	detected	detect	VBN
cord-273487-nfgjz6f9	113	36	in	in	IN
cord-273487-nfgjz6f9	113	37	all	all	DT
cord-273487-nfgjz6f9	113	38	of	of	IN
cord-273487-nfgjz6f9	113	39	the	the	DT
cord-273487-nfgjz6f9	113	40	infected	infected	JJ
cord-273487-nfgjz6f9	113	41	cell	cell	NN
cord-273487-nfgjz6f9	113	42	lysates	lysate	NNS
cord-273487-nfgjz6f9	113	43	.	.	.
cord-273487-nfgjz6f9	114	1	However	however	RB
cord-273487-nfgjz6f9	114	2	,	,	,
cord-273487-nfgjz6f9	114	3	expression	expression	NN
cord-273487-nfgjz6f9	114	4	of	of	IN
cord-273487-nfgjz6f9	114	5	DDX56-CT	DDX56-CT	NNP
cord-273487-nfgjz6f9	114	6	-	-	HYPH
cord-273487-nfgjz6f9	114	7	myc	myc	NNP
cord-273487-nfgjz6f9	114	8	reduced	reduce	VBN
cord-273487-nfgjz6f9	114	9	viral	viral	JJ
cord-273487-nfgjz6f9	114	10	titers	titer	NNS
cord-273487-nfgjz6f9	114	11	approximately	approximately	RB
cord-273487-nfgjz6f9	114	12	50-fold	50-fold	CD
cord-273487-nfgjz6f9	114	13	compared	compare	VBN
cord-273487-nfgjz6f9	114	14	to	to	IN
cord-273487-nfgjz6f9	114	15	expression	expression	NN
cord-273487-nfgjz6f9	114	16	of	of	IN
cord-273487-nfgjz6f9	114	17	full	full	JJ
cord-273487-nfgjz6f9	114	18	length	length	NN
cord-273487-nfgjz6f9	114	19	DDX56-myc	ddx56-myc	JJ
cord-273487-nfgjz6f9	114	20	or	or	CC
cord-273487-nfgjz6f9	114	21	NT	NT	NNP
cord-273487-nfgjz6f9	114	22	-	-	HYPH
cord-273487-nfgjz6f9	114	23	DDX56-myc	DDX56-myc	NNP
cord-273487-nfgjz6f9	114	24	(	(	-LRB-
cord-273487-nfgjz6f9	114	25	Fig	Fig	NNP
cord-273487-nfgjz6f9	114	26	.	.	.
cord-273487-nfgjz6f9	114	27	8B	8b	NN
cord-273487-nfgjz6f9	114	28	)	)	-RRB-
cord-273487-nfgjz6f9	114	29	.	.	.
cord-273487-nfgjz6f9	115	1	While	while	IN
cord-273487-nfgjz6f9	115	2	these	these	DT
cord-273487-nfgjz6f9	115	3	results	result	NNS
cord-273487-nfgjz6f9	115	4	suggest	suggest	VBP
cord-273487-nfgjz6f9	115	5	that	that	IN
cord-273487-nfgjz6f9	115	6	interaction	interaction	NN
cord-273487-nfgjz6f9	115	7	between	between	IN
cord-273487-nfgjz6f9	115	8	WNV	WNV	NNP
cord-273487-nfgjz6f9	115	9	capsid	capsid	NN
cord-273487-nfgjz6f9	115	10	and	and	CC
cord-273487-nfgjz6f9	115	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	115	12	is	be	VBZ
cord-273487-nfgjz6f9	115	13	important	important	JJ
cord-273487-nfgjz6f9	115	14	for	for	IN
cord-273487-nfgjz6f9	115	15	a	a	DT
cord-273487-nfgjz6f9	115	16	post	post	JJ
cord-273487-nfgjz6f9	115	17	-	-	JJ
cord-273487-nfgjz6f9	115	18	replication	replication	JJ
cord-273487-nfgjz6f9	115	19	step	step	NN
cord-273487-nfgjz6f9	115	20	in	in	IN
cord-273487-nfgjz6f9	115	21	the	the	DT
cord-273487-nfgjz6f9	115	22	WNV	WNV	NNP
cord-273487-nfgjz6f9	115	23	infection	infection	NN
cord-273487-nfgjz6f9	115	24	cycle	cycle	NN
cord-273487-nfgjz6f9	115	25	,	,	,
cord-273487-nfgjz6f9	115	26	assembly	assembly	NN
cord-273487-nfgjz6f9	115	27	and	and	CC
cord-273487-nfgjz6f9	115	28	secretion	secretion	NN
cord-273487-nfgjz6f9	115	29	of	of	IN
cord-273487-nfgjz6f9	115	30	WNV	WNV	NNP
cord-273487-nfgjz6f9	115	31	particles	particle	NNS
cord-273487-nfgjz6f9	115	32	was	be	VBD
cord-273487-nfgjz6f9	115	33	not	not	RB
cord-273487-nfgjz6f9	115	34	affected	affect	VBN
cord-273487-nfgjz6f9	115	35	(	(	-LRB-
cord-273487-nfgjz6f9	115	36	Fig	Fig	NNP
cord-273487-nfgjz6f9	115	37	.	.	.
cord-273487-nfgjz6f9	115	38	8C	8c	CD
cord-273487-nfgjz6f9	115	39	)	)	-RRB-
cord-273487-nfgjz6f9	115	40	.	.	.
cord-273487-nfgjz6f9	116	1	But	but	CC
cord-273487-nfgjz6f9	116	2	the	the	DT
cord-273487-nfgjz6f9	116	3	fact	fact	NN
cord-273487-nfgjz6f9	116	4	that	that	IN
cord-273487-nfgjz6f9	116	5	significantly	significantly	RB
cord-273487-nfgjz6f9	116	6	less	less	RBR
cord-273487-nfgjz6f9	116	7	viral	viral	JJ
cord-273487-nfgjz6f9	116	8	RNA	RNA	NNP
cord-273487-nfgjz6f9	116	9	was	be	VBD
cord-273487-nfgjz6f9	116	10	detected	detect	VBN
cord-273487-nfgjz6f9	116	11	in	in	IN
cord-273487-nfgjz6f9	116	12	the	the	DT
cord-273487-nfgjz6f9	116	13	virus	virus	NN
cord-273487-nfgjz6f9	116	14	particles	particle	NNS
cord-273487-nfgjz6f9	116	15	is	be	VBZ
cord-273487-nfgjz6f9	116	16	consistent	consistent	JJ
cord-273487-nfgjz6f9	116	17	with	with	IN
cord-273487-nfgjz6f9	116	18	our	-PRON-	PRP$
cord-273487-nfgjz6f9	116	19	hypothesis	hypothesis	NN
cord-273487-nfgjz6f9	116	20	that	that	IN
cord-273487-nfgjz6f9	116	21	capsid	capsid	RB
cord-273487-nfgjz6f9	116	22	-	-	HYPH
cord-273487-nfgjz6f9	116	23	DDX56	DDX56	VBG
cord-273487-nfgjz6f9	116	24	interactions	interaction	NNS
cord-273487-nfgjz6f9	116	25	are	be	VBP
cord-273487-nfgjz6f9	116	26	important	important	JJ
cord-273487-nfgjz6f9	116	27	for	for	IN
cord-273487-nfgjz6f9	116	28	incorporation	incorporation	NN
cord-273487-nfgjz6f9	116	29	packaging	packaging	NN
cord-273487-nfgjz6f9	116	30	viral	viral	JJ
cord-273487-nfgjz6f9	116	31	genome	genome	NN
cord-273487-nfgjz6f9	116	32	.	.	.
cord-273487-nfgjz6f9	117	1	Conventional	conventional	JJ
cord-273487-nfgjz6f9	117	2	antiviral	antiviral	JJ
cord-273487-nfgjz6f9	117	3	therapies	therapy	NNS
cord-273487-nfgjz6f9	117	4	involve	involve	VBP
cord-273487-nfgjz6f9	117	5	targeting	target	VBG
cord-273487-nfgjz6f9	117	6	virusencoded	virusencode	VBN
cord-273487-nfgjz6f9	117	7	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	117	8	that	that	WDT
cord-273487-nfgjz6f9	117	9	are	be	VBP
cord-273487-nfgjz6f9	117	10	required	require	VBN
cord-273487-nfgjz6f9	117	11	for	for	IN
cord-273487-nfgjz6f9	117	12	replication	replication	NN
cord-273487-nfgjz6f9	117	13	,	,	,
cord-273487-nfgjz6f9	117	14	processing	processing	NN
cord-273487-nfgjz6f9	117	15	of	of	IN
cord-273487-nfgjz6f9	117	16	polyproteins	polyprotein	NNS
cord-273487-nfgjz6f9	117	17	or	or	CC
cord-273487-nfgjz6f9	117	18	viral	viral	JJ
cord-273487-nfgjz6f9	117	19	egress	egress	NN
cord-273487-nfgjz6f9	117	20	from	from	IN
cord-273487-nfgjz6f9	117	21	host	host	NN
cord-273487-nfgjz6f9	117	22	cells	cell	NNS
cord-273487-nfgjz6f9	117	23	.	.	.
cord-273487-nfgjz6f9	118	1	While	while	IN
cord-273487-nfgjz6f9	118	2	there	there	EX
cord-273487-nfgjz6f9	118	3	have	have	VBP
cord-273487-nfgjz6f9	118	4	been	be	VBN
cord-273487-nfgjz6f9	118	5	In	in	IN
cord-273487-nfgjz6f9	118	6	the	the	DT
cord-273487-nfgjz6f9	118	7	right	right	JJ
cord-273487-nfgjz6f9	118	8	panel	panel	NN
cord-273487-nfgjz6f9	118	9	,	,	,
cord-273487-nfgjz6f9	118	10	cell	cell	NN
cord-273487-nfgjz6f9	118	11	lysates	lysate	NNS
cord-273487-nfgjz6f9	118	12	were	be	VBD
cord-273487-nfgjz6f9	118	13	subjected	subject	VBN
cord-273487-nfgjz6f9	118	14	to	to	IN
cord-273487-nfgjz6f9	118	15	immunoprecipitation	immunoprecipitation	NN
cord-273487-nfgjz6f9	118	16	followed	follow	VBN
cord-273487-nfgjz6f9	118	17	by	by	IN
cord-273487-nfgjz6f9	118	18	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	118	19	with	with	IN
cord-273487-nfgjz6f9	118	20	antibodies	antibody	NNS
cord-273487-nfgjz6f9	118	21	to	to	IN
cord-273487-nfgjz6f9	118	22	myc	myc	NNP
cord-273487-nfgjz6f9	118	23	and	and	CC
cord-273487-nfgjz6f9	118	24	capsid	capsid	NN
cord-273487-nfgjz6f9	118	25	.	.	.
cord-273487-nfgjz6f9	119	1	The	the	DT
cord-273487-nfgjz6f9	119	2	protein	protein	NN
cord-273487-nfgjz6f9	119	3	marked	mark	VBN
cord-273487-nfgjz6f9	119	4	by	by	IN
cord-273487-nfgjz6f9	119	5	n	n	NNP
cord-273487-nfgjz6f9	119	6	is	be	VBZ
cord-273487-nfgjz6f9	119	7	IgG	IgG	NNP
cord-273487-nfgjz6f9	119	8	light	light	NN
cord-273487-nfgjz6f9	119	9	chain	chain	NN
cord-273487-nfgjz6f9	119	10	.	.	.
cord-273487-nfgjz6f9	120	1	(	(	-LRB-
cord-273487-nfgjz6f9	120	2	C	C	NNP
cord-273487-nfgjz6f9	120	3	)	)	-RRB-
cord-273487-nfgjz6f9	121	1	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	121	2	T	t	NN
cord-273487-nfgjz6f9	121	3	cells	cell	NNS
cord-273487-nfgjz6f9	121	4	were	be	VBD
cord-273487-nfgjz6f9	121	5	co	co	JJ
cord-273487-nfgjz6f9	121	6	-	-	VBN
cord-273487-nfgjz6f9	121	7	transfected	transfecte	VBN
cord-273487-nfgjz6f9	121	8	with	with	IN
cord-273487-nfgjz6f9	121	9	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	121	10	encoding	encode	VBG
cord-273487-nfgjz6f9	121	11	GST	gst	NN
cord-273487-nfgjz6f9	121	12	-	-	HYPH
cord-273487-nfgjz6f9	121	13	capsid	capsid	NN
cord-273487-nfgjz6f9	121	14	together	together	RB
cord-273487-nfgjz6f9	121	15	with	with	IN
cord-273487-nfgjz6f9	121	16	WT	WT	NNP
cord-273487-nfgjz6f9	121	17	,	,	,
cord-273487-nfgjz6f9	121	18	NT	NT	NNP
cord-273487-nfgjz6f9	121	19	and	and	CC
cord-273487-nfgjz6f9	121	20	CT	CT	NNP
cord-273487-nfgjz6f9	121	21	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	121	22	constructs	construct	NNS
cord-273487-nfgjz6f9	121	23	or	or	CC
cord-273487-nfgjz6f9	121	24	vector	vector	VB
cord-273487-nfgjz6f9	121	25	alone	alone	RB
cord-273487-nfgjz6f9	121	26	.	.	.
cord-273487-nfgjz6f9	122	1	In	in	IN
cord-273487-nfgjz6f9	122	2	the	the	DT
cord-273487-nfgjz6f9	122	3	left	left	JJ
cord-273487-nfgjz6f9	122	4	panel	panel	NN
cord-273487-nfgjz6f9	122	5	,	,	,
cord-273487-nfgjz6f9	122	6	relative	relative	JJ
cord-273487-nfgjz6f9	122	7	levels	level	NNS
cord-273487-nfgjz6f9	122	8	of	of	IN
cord-273487-nfgjz6f9	122	9	myc	myc	NNP
cord-273487-nfgjz6f9	122	10	-	-	HYPH
cord-273487-nfgjz6f9	122	11	tagged	tag	VBN
cord-273487-nfgjz6f9	122	12	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	122	13	proteins	protein	NNS
cord-273487-nfgjz6f9	122	14	and	and	CC
cord-273487-nfgjz6f9	122	15	capsid	capsid	NN
cord-273487-nfgjz6f9	122	16	were	be	VBD
cord-273487-nfgjz6f9	122	17	determined	determine	VBN
cord-273487-nfgjz6f9	122	18	in	in	IN
cord-273487-nfgjz6f9	122	19	whole	whole	JJ
cord-273487-nfgjz6f9	122	20	cell	cell	NN
cord-273487-nfgjz6f9	122	21	lysates	lysate	NNS
cord-273487-nfgjz6f9	122	22	(	(	-LRB-
cord-273487-nfgjz6f9	122	23	WCL	WCL	NNP
cord-273487-nfgjz6f9	122	24	)	)	-RRB-
cord-273487-nfgjz6f9	122	25	by	by	IN
cord-273487-nfgjz6f9	122	26	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	122	27	with	with	IN
cord-273487-nfgjz6f9	122	28	antibodies	antibody	NNS
cord-273487-nfgjz6f9	122	29	to	to	IN
cord-273487-nfgjz6f9	122	30	the	the	DT
cord-273487-nfgjz6f9	122	31	myc	myc	NNP
cord-273487-nfgjz6f9	122	32	epitope	epitope	NNP
cord-273487-nfgjz6f9	122	33	and	and	CC
cord-273487-nfgjz6f9	122	34	GST	GST	NNP
cord-273487-nfgjz6f9	122	35	.	.	.
cord-273487-nfgjz6f9	123	1	In	in	IN
cord-273487-nfgjz6f9	123	2	the	the	DT
cord-273487-nfgjz6f9	123	3	right	right	JJ
cord-273487-nfgjz6f9	123	4	panel	panel	NN
cord-273487-nfgjz6f9	123	5	,	,	,
cord-273487-nfgjz6f9	123	6	cell	cell	NN
cord-273487-nfgjz6f9	123	7	lysates	lysate	NNS
cord-273487-nfgjz6f9	123	8	were	be	VBD
cord-273487-nfgjz6f9	123	9	subjected	subject	VBN
cord-273487-nfgjz6f9	123	10	to	to	IN
cord-273487-nfgjz6f9	123	11	GST	gst	NN
cord-273487-nfgjz6f9	123	12	-	-	HYPH
cord-273487-nfgjz6f9	123	13	pulldown	pulldown	NN
cord-273487-nfgjz6f9	123	14	followed	follow	VBN
cord-273487-nfgjz6f9	123	15	by	by	IN
cord-273487-nfgjz6f9	123	16	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	123	17	with	with	IN
cord-273487-nfgjz6f9	123	18	antibodies	antibody	NNS
cord-273487-nfgjz6f9	123	19	to	to	IN
cord-273487-nfgjz6f9	123	20	myc	myc	NNP
cord-273487-nfgjz6f9	123	21	and	and	CC
cord-273487-nfgjz6f9	123	22	GST	GST	NNP
cord-273487-nfgjz6f9	123	23	.	.	.
cord-273487-nfgjz6f9	124	1	(	(	-LRB-
cord-273487-nfgjz6f9	124	2	D	d	NN
cord-273487-nfgjz6f9	124	3	)	)	-RRB-
cord-273487-nfgjz6f9	125	1	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	125	2	T	t	NN
cord-273487-nfgjz6f9	125	3	cells	cell	NNS
cord-273487-nfgjz6f9	125	4	were	be	VBD
cord-273487-nfgjz6f9	125	5	co	co	JJ
cord-273487-nfgjz6f9	125	6	-	-	VBN
cord-273487-nfgjz6f9	125	7	transfected	transfecte	VBN
cord-273487-nfgjz6f9	125	8	with	with	IN
cord-273487-nfgjz6f9	125	9	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	125	10	encoding	encode	VBG
cord-273487-nfgjz6f9	125	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	125	12	constructs	construct	NNS
cord-273487-nfgjz6f9	125	13	and	and	CC
cord-273487-nfgjz6f9	125	14	then	then	RB
cord-273487-nfgjz6f9	125	15	infected	infect	VBN
cord-273487-nfgjz6f9	125	16	with	with	IN
cord-273487-nfgjz6f9	125	17	WNV	WNV	NNP
cord-273487-nfgjz6f9	125	18	.	.	.
cord-273487-nfgjz6f9	126	1	In	in	IN
cord-273487-nfgjz6f9	126	2	the	the	DT
cord-273487-nfgjz6f9	126	3	left	left	JJ
cord-273487-nfgjz6f9	126	4	panel	panel	NN
cord-273487-nfgjz6f9	126	5	,	,	,
cord-273487-nfgjz6f9	126	6	relative	relative	JJ
cord-273487-nfgjz6f9	126	7	levels	level	NNS
cord-273487-nfgjz6f9	126	8	of	of	IN
cord-273487-nfgjz6f9	126	9	myc	myc	NNP
cord-273487-nfgjz6f9	126	10	-	-	HYPH
cord-273487-nfgjz6f9	126	11	tagged	tag	VBN
cord-273487-nfgjz6f9	126	12	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	126	13	proteins	protein	NNS
cord-273487-nfgjz6f9	126	14	and	and	CC
cord-273487-nfgjz6f9	126	15	capsid	capsid	NN
cord-273487-nfgjz6f9	126	16	were	be	VBD
cord-273487-nfgjz6f9	126	17	determine	determine	NN
cord-273487-nfgjz6f9	126	18	in	in	IN
cord-273487-nfgjz6f9	126	19	whole	whole	JJ
cord-273487-nfgjz6f9	126	20	cell	cell	NN
cord-273487-nfgjz6f9	126	21	lysates	lysate	NNS
cord-273487-nfgjz6f9	126	22	(	(	-LRB-
cord-273487-nfgjz6f9	126	23	WCL	WCL	NNP
cord-273487-nfgjz6f9	126	24	)	)	-RRB-
cord-273487-nfgjz6f9	126	25	by	by	IN
cord-273487-nfgjz6f9	126	26	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	126	27	with	with	IN
cord-273487-nfgjz6f9	126	28	antibodies	antibody	NNS
cord-273487-nfgjz6f9	126	29	to	to	IN
cord-273487-nfgjz6f9	126	30	the	the	DT
cord-273487-nfgjz6f9	126	31	myc	myc	NNP
cord-273487-nfgjz6f9	126	32	epitope	epitope	NNP
cord-273487-nfgjz6f9	126	33	and	and	CC
cord-273487-nfgjz6f9	126	34	WNV	WNV	NNP
cord-273487-nfgjz6f9	126	35	capsid	capsid	NN
cord-273487-nfgjz6f9	126	36	protein	protein	NN
cord-273487-nfgjz6f9	126	37	.	.	.
cord-273487-nfgjz6f9	127	1	In	in	IN
cord-273487-nfgjz6f9	127	2	the	the	DT
cord-273487-nfgjz6f9	127	3	right	right	JJ
cord-273487-nfgjz6f9	127	4	panel	panel	NN
cord-273487-nfgjz6f9	127	5	,	,	,
cord-273487-nfgjz6f9	127	6	cell	cell	NN
cord-273487-nfgjz6f9	127	7	lysates	lysate	NNS
cord-273487-nfgjz6f9	127	8	were	be	VBD
cord-273487-nfgjz6f9	127	9	subjected	subject	VBN
cord-273487-nfgjz6f9	127	10	to	to	IN
cord-273487-nfgjz6f9	127	11	immunoprecipitation	immunoprecipitation	NN
cord-273487-nfgjz6f9	127	12	by	by	IN
cord-273487-nfgjz6f9	127	13	anti	anti	JJ
cord-273487-nfgjz6f9	127	14	-	-	JJ
cord-273487-nfgjz6f9	127	15	capsid	capsid	JJ
cord-273487-nfgjz6f9	127	16	antibody	antibody	NN
cord-273487-nfgjz6f9	127	17	followed	follow	VBN
cord-273487-nfgjz6f9	127	18	by	by	IN
cord-273487-nfgjz6f9	127	19	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	127	20	with	with	IN
cord-273487-nfgjz6f9	127	21	antibodies	antibody	NNS
cord-273487-nfgjz6f9	127	22	to	to	IN
cord-273487-nfgjz6f9	127	23	myc	myc	NNP
cord-273487-nfgjz6f9	127	24	and	and	CC
cord-273487-nfgjz6f9	127	25	capsid	capsid	NN
cord-273487-nfgjz6f9	127	26	.	.	.
cord-273487-nfgjz6f9	128	1	notable	notable	JJ
cord-273487-nfgjz6f9	128	2	successes	success	NNS
cord-273487-nfgjz6f9	128	3	using	use	VBG
cord-273487-nfgjz6f9	128	4	this	this	DT
cord-273487-nfgjz6f9	128	5	approach	approach	NN
cord-273487-nfgjz6f9	128	6	,	,	,
cord-273487-nfgjz6f9	128	7	it	-PRON-	PRP
cord-273487-nfgjz6f9	128	8	suffers	suffer	VBZ
cord-273487-nfgjz6f9	128	9	from	from	IN
cord-273487-nfgjz6f9	128	10	a	a	DT
cord-273487-nfgjz6f9	128	11	number	number	NN
cord-273487-nfgjz6f9	128	12	of	of	IN
cord-273487-nfgjz6f9	128	13	limitations	limitation	NNS
cord-273487-nfgjz6f9	128	14	.	.	.
cord-273487-nfgjz6f9	129	1	First	first	RB
cord-273487-nfgjz6f9	129	2	,	,	,
cord-273487-nfgjz6f9	129	3	viruses	virus	NNS
cord-273487-nfgjz6f9	129	4	almost	almost	RB
cord-273487-nfgjz6f9	129	5	invariably	invariably	RB
cord-273487-nfgjz6f9	129	6	develop	develop	VBP
cord-273487-nfgjz6f9	129	7	resistance	resistance	NN
cord-273487-nfgjz6f9	129	8	to	to	IN
cord-273487-nfgjz6f9	129	9	these	these	DT
cord-273487-nfgjz6f9	129	10	types	type	NNS
cord-273487-nfgjz6f9	129	11	of	of	IN
cord-273487-nfgjz6f9	129	12	drugs	drug	NNS
cord-273487-nfgjz6f9	129	13	.	.	.
cord-273487-nfgjz6f9	130	1	This	this	DT
cord-273487-nfgjz6f9	130	2	is	be	VBZ
cord-273487-nfgjz6f9	130	3	particularly	particularly	RB
cord-273487-nfgjz6f9	130	4	true	true	JJ
cord-273487-nfgjz6f9	130	5	of	of	IN
cord-273487-nfgjz6f9	130	6	RNA	RNA	NNP
cord-273487-nfgjz6f9	130	7	viruses	virus	NNS
cord-273487-nfgjz6f9	130	8	whose	whose	WP$
cord-273487-nfgjz6f9	130	9	polymerases	polymerase	NNS
cord-273487-nfgjz6f9	130	10	do	do	VBP
cord-273487-nfgjz6f9	130	11	not	not	RB
cord-273487-nfgjz6f9	130	12	possess	possess	VB
cord-273487-nfgjz6f9	130	13	proof	proof	JJ
cord-273487-nfgjz6f9	130	14	reading	read	VBG
cord-273487-nfgjz6f9	130	15	activity	activity	NN
cord-273487-nfgjz6f9	130	16	and	and	CC
cord-273487-nfgjz6f9	130	17	are	be	VBP
cord-273487-nfgjz6f9	130	18	therefore	therefore	RB
cord-273487-nfgjz6f9	130	19	by	by	IN
cord-273487-nfgjz6f9	130	20	nature	nature	NN
cord-273487-nfgjz6f9	130	21	,	,	,
cord-273487-nfgjz6f9	130	22	error	error	NN
cord-273487-nfgjz6f9	130	23	prone	prone	JJ
cord-273487-nfgjz6f9	130	24	and	and	CC
cord-273487-nfgjz6f9	130	25	mutable	mutable	JJ
cord-273487-nfgjz6f9	130	26	.	.	.
cord-273487-nfgjz6f9	131	1	Second	second	RB
cord-273487-nfgjz6f9	131	2	,	,	,
cord-273487-nfgjz6f9	131	3	the	the	DT
cord-273487-nfgjz6f9	131	4	choice	choice	NN
cord-273487-nfgjz6f9	131	5	of	of	IN
cord-273487-nfgjz6f9	131	6	targets	target	NNS
cord-273487-nfgjz6f9	131	7	is	be	VBZ
cord-273487-nfgjz6f9	131	8	very	very	RB
cord-273487-nfgjz6f9	131	9	limited	limited	JJ
cord-273487-nfgjz6f9	131	10	due	due	IN
cord-273487-nfgjz6f9	131	11	to	to	IN
cord-273487-nfgjz6f9	131	12	the	the	DT
cord-273487-nfgjz6f9	131	13	small	small	JJ
cord-273487-nfgjz6f9	131	14	number	number	NN
cord-273487-nfgjz6f9	131	15	of	of	IN
cord-273487-nfgjz6f9	131	16	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	131	17	encoded	encode	VBN
cord-273487-nfgjz6f9	131	18	by	by	IN
cord-273487-nfgjz6f9	131	19	most	most	JJS
cord-273487-nfgjz6f9	131	20	viruses	virus	NNS
cord-273487-nfgjz6f9	131	21	.	.	.
cord-273487-nfgjz6f9	132	1	In	in	IN
cord-273487-nfgjz6f9	132	2	contrast	contrast	NN
cord-273487-nfgjz6f9	132	3	,	,	,
cord-273487-nfgjz6f9	132	4	targeting	target	VBG
cord-273487-nfgjz6f9	132	5	host	host	NN
cord-273487-nfgjz6f9	132	6	factors	factor	NNS
cord-273487-nfgjz6f9	132	7	as	as	IN
cord-273487-nfgjz6f9	132	8	means	mean	VBZ
cord-273487-nfgjz6f9	132	9	to	to	TO
cord-273487-nfgjz6f9	132	10	control	control	VB
cord-273487-nfgjz6f9	132	11	viral	viral	JJ
cord-273487-nfgjz6f9	132	12	infection	infection	NN
cord-273487-nfgjz6f9	132	13	is	be	VBZ
cord-273487-nfgjz6f9	132	14	a	a	DT
cord-273487-nfgjz6f9	132	15	burgeoning	burgeon	VBG
cord-273487-nfgjz6f9	132	16	area	area	NN
cord-273487-nfgjz6f9	132	17	that	that	WDT
cord-273487-nfgjz6f9	132	18	has	have	VBZ
cord-273487-nfgjz6f9	132	19	shown	show	VBN
cord-273487-nfgjz6f9	132	20	promise	promise	NN
cord-273487-nfgjz6f9	132	21	,	,	,
cord-273487-nfgjz6f9	132	22	particularly	particularly	RB
cord-273487-nfgjz6f9	132	23	for	for	IN
cord-273487-nfgjz6f9	132	24	flaviviruses	flavivirus	NNS
cord-273487-nfgjz6f9	132	25	.	.	.
cord-273487-nfgjz6f9	133	1	Replication	replication	NN
cord-273487-nfgjz6f9	133	2	and	and	CC
cord-273487-nfgjz6f9	133	3	assembly	assembly	NN
cord-273487-nfgjz6f9	133	4	of	of	IN
cord-273487-nfgjz6f9	133	5	infectious	infectious	JJ
cord-273487-nfgjz6f9	133	6	flavivirus	flavivirus	NNP
cord-273487-nfgjz6f9	133	7	particles	particle	NNS
cord-273487-nfgjz6f9	133	8	requires	require	VBZ
cord-273487-nfgjz6f9	133	9	hundreds	hundred	NNS
cord-273487-nfgjz6f9	133	10	of	of	IN
cord-273487-nfgjz6f9	133	11	host	host	NN
cord-273487-nfgjz6f9	133	12	genes	gene	NNS
cord-273487-nfgjz6f9	133	13	(	(	-LRB-
cord-273487-nfgjz6f9	133	14	Krishnan	Krishnan	NNP
cord-273487-nfgjz6f9	133	15	et	et	NNP
cord-273487-nfgjz6f9	133	16	al	al	NNP
cord-273487-nfgjz6f9	133	17	.	.	NNP
cord-273487-nfgjz6f9	133	18	,	,	,
cord-273487-nfgjz6f9	133	19	2008	2008	CD
cord-273487-nfgjz6f9	133	20	)	)	-RRB-
cord-273487-nfgjz6f9	133	21	.	.	.
cord-273487-nfgjz6f9	134	1	Accordingly	accordingly	RB
cord-273487-nfgjz6f9	134	2	,	,	,
cord-273487-nfgjz6f9	134	3	it	-PRON-	PRP
cord-273487-nfgjz6f9	134	4	may	may	MD
cord-273487-nfgjz6f9	134	5	be	be	VB
cord-273487-nfgjz6f9	134	6	possible	possible	JJ
cord-273487-nfgjz6f9	134	7	to	to	TO
cord-273487-nfgjz6f9	134	8	target	target	VB
cord-273487-nfgjz6f9	134	9	a	a	DT
cord-273487-nfgjz6f9	134	10	variety	variety	NN
cord-273487-nfgjz6f9	134	11	of	of	IN
cord-273487-nfgjz6f9	134	12	host	host	NN
cord-273487-nfgjz6f9	134	13	proteins	protein	NNS
cord-273487-nfgjz6f9	134	14	,	,	,
cord-273487-nfgjz6f9	134	15	particularly	particularly	RB
cord-273487-nfgjz6f9	134	16	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	134	17	,	,	,
cord-273487-nfgjz6f9	134	18	as	as	IN
cord-273487-nfgjz6f9	134	19	a	a	DT
cord-273487-nfgjz6f9	134	20	means	means	NN
cord-273487-nfgjz6f9	134	21	to	to	TO
cord-273487-nfgjz6f9	134	22	control	control	VB
cord-273487-nfgjz6f9	134	23	viral	viral	JJ
cord-273487-nfgjz6f9	134	24	infection	infection	NN
cord-273487-nfgjz6f9	134	25	.	.	.
cord-273487-nfgjz6f9	135	1	Although	although	IN
cord-273487-nfgjz6f9	135	2	this	this	DT
cord-273487-nfgjz6f9	135	3	approach	approach	NN
cord-273487-nfgjz6f9	135	4	may	may	MD
cord-273487-nfgjz6f9	135	5	also	also	RB
cord-273487-nfgjz6f9	135	6	have	have	VB
cord-273487-nfgjz6f9	135	7	drawbacks	drawback	NNS
cord-273487-nfgjz6f9	135	8	,	,	,
cord-273487-nfgjz6f9	135	9	viral	viral	JJ
cord-273487-nfgjz6f9	135	10	resistance	resistance	NN
cord-273487-nfgjz6f9	135	11	to	to	IN
cord-273487-nfgjz6f9	135	12	small	small	JJ
cord-273487-nfgjz6f9	135	13	molecules	molecule	NNS
cord-273487-nfgjz6f9	135	14	that	that	WDT
cord-273487-nfgjz6f9	135	15	block	block	VBP
cord-273487-nfgjz6f9	135	16	host	host	NN
cord-273487-nfgjz6f9	135	17	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	135	18	should	should	MD
cord-273487-nfgjz6f9	135	19	be	be	VB
cord-273487-nfgjz6f9	135	20	minimal	minimal	JJ
cord-273487-nfgjz6f9	135	21	.	.	.
cord-273487-nfgjz6f9	136	1	RNA	RNA	NNP
cord-273487-nfgjz6f9	136	2	helicases	helicase	NNS
cord-273487-nfgjz6f9	136	3	are	be	VBP
cord-273487-nfgjz6f9	136	4	one	one	CD
cord-273487-nfgjz6f9	136	5	class	class	NN
cord-273487-nfgjz6f9	136	6	of	of	IN
cord-273487-nfgjz6f9	136	7	host	host	NN
cord-273487-nfgjz6f9	136	8	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	136	9	that	that	WDT
cord-273487-nfgjz6f9	136	10	have	have	VBP
cord-273487-nfgjz6f9	136	11	been	be	VBN
cord-273487-nfgjz6f9	136	12	proposed	propose	VBN
cord-273487-nfgjz6f9	136	13	as	as	IN
cord-273487-nfgjz6f9	136	14	anti	anti	JJ
cord-273487-nfgjz6f9	136	15	-	-	JJ
cord-273487-nfgjz6f9	136	16	viral	viral	JJ
cord-273487-nfgjz6f9	136	17	targets	target	NNS
cord-273487-nfgjz6f9	136	18	(	(	-LRB-
cord-273487-nfgjz6f9	136	19	Geiss	Geiss	NNP
cord-273487-nfgjz6f9	136	20	et	et	NNP
cord-273487-nfgjz6f9	136	21	al	al	NNP
cord-273487-nfgjz6f9	136	22	.	.	NNP
cord-273487-nfgjz6f9	136	23	,	,	,
cord-273487-nfgjz6f9	136	24	2009	2009	CD
cord-273487-nfgjz6f9	136	25	;	;	:
cord-273487-nfgjz6f9	136	26	Kwong	Kwong	NNP
cord-273487-nfgjz6f9	136	27	et	et	NNP
cord-273487-nfgjz6f9	136	28	al	al	NNP
cord-273487-nfgjz6f9	136	29	.	.	NNP
cord-273487-nfgjz6f9	136	30	,	,	,
cord-273487-nfgjz6f9	136	31	2005	2005	CD
cord-273487-nfgjz6f9	136	32	;	;	:
cord-273487-nfgjz6f9	137	1	Maga	Maga	NNP
cord-273487-nfgjz6f9	137	2	et	et	NNP
cord-273487-nfgjz6f9	137	3	al	al	NNP
cord-273487-nfgjz6f9	137	4	.	.	NNP
cord-273487-nfgjz6f9	137	5	,	,	,
cord-273487-nfgjz6f9	137	6	2011	2011	CD
cord-273487-nfgjz6f9	137	7	;	;	:
cord-273487-nfgjz6f9	137	8	Stankiewicz	Stankiewicz	NNP
cord-273487-nfgjz6f9	137	9	-	-	HYPH
cord-273487-nfgjz6f9	137	10	Drogon	Drogon	NNP
cord-273487-nfgjz6f9	137	11	et	et	NNP
cord-273487-nfgjz6f9	137	12	al	al	NNP
cord-273487-nfgjz6f9	137	13	.	.	NNP
cord-273487-nfgjz6f9	137	14	,	,	,
cord-273487-nfgjz6f9	137	15	2010	2010	CD
cord-273487-nfgjz6f9	137	16	)	)	-RRB-
cord-273487-nfgjz6f9	137	17	.	.	.
cord-273487-nfgjz6f9	138	1	Among	among	IN
cord-273487-nfgjz6f9	138	2	the	the	DT
cord-273487-nfgjz6f9	138	3	helicase	helicase	NN
cord-273487-nfgjz6f9	138	4	superfamily	superfamily	NN
cord-273487-nfgjz6f9	138	5	,	,	,
cord-273487-nfgjz6f9	138	6	DEAD	dead	JJ
cord-273487-nfgjz6f9	138	7	box	box	NN
cord-273487-nfgjz6f9	138	8	proteins	protein	NNS
cord-273487-nfgjz6f9	138	9	form	form	VBP
cord-273487-nfgjz6f9	138	10	the	the	DT
cord-273487-nfgjz6f9	138	11	largest	large	JJS
cord-273487-nfgjz6f9	138	12	group	group	NN
cord-273487-nfgjz6f9	138	13	of	of	IN
cord-273487-nfgjz6f9	138	14	these	these	DT
cord-273487-nfgjz6f9	138	15	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	138	16	.	.	.
cord-273487-nfgjz6f9	139	1	These	these	DT
cord-273487-nfgjz6f9	139	2	helicases	helicase	NNS
cord-273487-nfgjz6f9	139	3	are	be	VBP
cord-273487-nfgjz6f9	139	4	thought	think	VBN
cord-273487-nfgjz6f9	139	5	to	to	TO
cord-273487-nfgjz6f9	139	6	play	play	VB
cord-273487-nfgjz6f9	139	7	multiple	multiple	JJ
cord-273487-nfgjz6f9	139	8	roles	role	NNS
cord-273487-nfgjz6f9	139	9	in	in	IN
cord-273487-nfgjz6f9	139	10	RNA	RNA	NNP
cord-273487-nfgjz6f9	139	11	metabolism	metabolism	NN
cord-273487-nfgjz6f9	139	12	including	include	VBG
cord-273487-nfgjz6f9	139	13	mRNA	mrna	NN
cord-273487-nfgjz6f9	139	14	splicing	splicing	NN
cord-273487-nfgjz6f9	139	15	and	and	CC
cord-273487-nfgjz6f9	139	16	transport	transport	NN
cord-273487-nfgjz6f9	139	17	,	,	,
cord-273487-nfgjz6f9	139	18	transcription	transcription	NN
cord-273487-nfgjz6f9	139	19	,	,	,
cord-273487-nfgjz6f9	139	20	translation	translation	NN
cord-273487-nfgjz6f9	139	21	and	and	CC
cord-273487-nfgjz6f9	139	22	remodeling	remodeling	NN
cord-273487-nfgjz6f9	139	23	of	of	IN
cord-273487-nfgjz6f9	139	24	ribonucleoprotein	ribonucleoprotein	NN
cord-273487-nfgjz6f9	139	25	complexes	complex	NNS
cord-273487-nfgjz6f9	139	26	.	.	.
cord-273487-nfgjz6f9	140	1	In	in	IN
cord-273487-nfgjz6f9	140	2	most	most	JJS
cord-273487-nfgjz6f9	140	3	cases	case	NNS
cord-273487-nfgjz6f9	140	4	,	,	,
cord-273487-nfgjz6f9	140	5	the	the	DT
cord-273487-nfgjz6f9	140	6	physiological	physiological	JJ
cord-273487-nfgjz6f9	140	7	substrates	substrate	NNS
cord-273487-nfgjz6f9	140	8	of	of	IN
cord-273487-nfgjz6f9	140	9	DEAD	dead	JJ
cord-273487-nfgjz6f9	140	10	box	box	NN
cord-273487-nfgjz6f9	140	11	helicases	helicase	NNS
cord-273487-nfgjz6f9	140	12	have	have	VBP
cord-273487-nfgjz6f9	140	13	not	not	RB
cord-273487-nfgjz6f9	140	14	been	be	VBN
cord-273487-nfgjz6f9	140	15	defined	define	VBN
cord-273487-nfgjz6f9	140	16	but	but	CC
cord-273487-nfgjz6f9	140	17	it	-PRON-	PRP
cord-273487-nfgjz6f9	140	18	is	be	VBZ
cord-273487-nfgjz6f9	140	19	clear	clear	JJ
cord-273487-nfgjz6f9	140	20	that	that	IN
cord-273487-nfgjz6f9	140	21	a	a	DT
cord-273487-nfgjz6f9	140	22	number	number	NN
cord-273487-nfgjz6f9	140	23	of	of	IN
cord-273487-nfgjz6f9	140	24	pathogenic	pathogenic	JJ
cord-273487-nfgjz6f9	140	25	RNA	RNA	NNP
cord-273487-nfgjz6f9	140	26	viruses	virus	NNS
cord-273487-nfgjz6f9	140	27	require	require	VBP
cord-273487-nfgjz6f9	140	28	these	these	DT
cord-273487-nfgjz6f9	140	29	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	140	30	for	for	IN
cord-273487-nfgjz6f9	140	31	replication	replication	NN
cord-273487-nfgjz6f9	140	32	and/or	and/or	CC
cord-273487-nfgjz6f9	140	33	assembly	assembly	NN
cord-273487-nfgjz6f9	140	34	.	.	.
cord-273487-nfgjz6f9	141	1	For	for	IN
cord-273487-nfgjz6f9	141	2	example	example	NN
cord-273487-nfgjz6f9	141	3	,	,	,
cord-273487-nfgjz6f9	141	4	at	at	RB
cord-273487-nfgjz6f9	141	5	least	least	RBS
cord-273487-nfgjz6f9	141	6	two	two	CD
cord-273487-nfgjz6f9	141	7	cellular	cellular	JJ
cord-273487-nfgjz6f9	141	8	helicases	helicase	NNS
cord-273487-nfgjz6f9	141	9	,	,	,
cord-273487-nfgjz6f9	141	10	DDX1	DDX1	NNP
cord-273487-nfgjz6f9	141	11	and	and	CC
cord-273487-nfgjz6f9	141	12	DDX3	DDX3	NNP
cord-273487-nfgjz6f9	141	13	function	function	NN
cord-273487-nfgjz6f9	141	14	as	as	IN
cord-273487-nfgjz6f9	141	15	cofactors	cofactor	NNS
cord-273487-nfgjz6f9	141	16	that	that	WDT
cord-273487-nfgjz6f9	141	17	promote	promote	VBP
cord-273487-nfgjz6f9	141	18	replication	replication	NN
cord-273487-nfgjz6f9	141	19	of	of	IN
cord-273487-nfgjz6f9	141	20	HIV	HIV	NNP
cord-273487-nfgjz6f9	142	1	(	(	-LRB-
cord-273487-nfgjz6f9	142	2	Fang	Fang	NNP
cord-273487-nfgjz6f9	142	3	et	et	FW
cord-273487-nfgjz6f9	142	4	al	al	NNP
cord-273487-nfgjz6f9	142	5	.	.	NNP
cord-273487-nfgjz6f9	142	6	,	,	,
cord-273487-nfgjz6f9	142	7	2004	2004	CD
cord-273487-nfgjz6f9	142	8	;	;	:
cord-273487-nfgjz6f9	142	9	Yedavalli	Yedavalli	NNP
cord-273487-nfgjz6f9	142	10	et	et	NNP
cord-273487-nfgjz6f9	142	11	al	al	NNP
cord-273487-nfgjz6f9	142	12	.	.	NNP
cord-273487-nfgjz6f9	142	13	,	,	,
cord-273487-nfgjz6f9	142	14	2004	2004	CD
cord-273487-nfgjz6f9	142	15	)	)	-RRB-
cord-273487-nfgjz6f9	142	16	.	.	.
cord-273487-nfgjz6f9	143	1	DDX1	DDX1	NNP
cord-273487-nfgjz6f9	143	2	and	and	CC
cord-273487-nfgjz6f9	143	3	DDX3	DDX3	NNP
cord-273487-nfgjz6f9	143	4	both	both	DT
cord-273487-nfgjz6f9	143	5	appear	appear	VBP
cord-273487-nfgjz6f9	143	6	to	to	TO
cord-273487-nfgjz6f9	143	7	facilitate	facilitate	VB
cord-273487-nfgjz6f9	143	8	export	export	NN
cord-273487-nfgjz6f9	143	9	of	of	IN
cord-273487-nfgjz6f9	143	10	HIV	HIV	NNP
cord-273487-nfgjz6f9	143	11	RNA	RNA	NNP
cord-273487-nfgjz6f9	143	12	from	from	IN
cord-273487-nfgjz6f9	143	13	the	the	DT
cord-273487-nfgjz6f9	143	14	nucleus	nucleus	NN
cord-273487-nfgjz6f9	143	15	to	to	IN
cord-273487-nfgjz6f9	143	16	the	the	DT
cord-273487-nfgjz6f9	143	17	cytoplasm	cytoplasm	NN
cord-273487-nfgjz6f9	143	18	through	through	IN
cord-273487-nfgjz6f9	143	19	interaction	interaction	NN
cord-273487-nfgjz6f9	143	20	with	with	IN
cord-273487-nfgjz6f9	143	21	Rev.	Rev.	NNP
cord-273487-nfgjz6f9	143	22	DDX1	DDX1	NNP
cord-273487-nfgjz6f9	144	1	also	also	RB
cord-273487-nfgjz6f9	144	2	stimulates	stimulate	VBZ
cord-273487-nfgjz6f9	144	3	replication	replication	NN
cord-273487-nfgjz6f9	144	4	of	of	IN
cord-273487-nfgjz6f9	144	5	coronavirus	coronavirus	NN
cord-273487-nfgjz6f9	144	6	RNA	RNA	NNP
cord-273487-nfgjz6f9	144	7	(	(	-LRB-
cord-273487-nfgjz6f9	144	8	Xu	Xu	NNP
cord-273487-nfgjz6f9	144	9	et	et	NNP
cord-273487-nfgjz6f9	144	10	al	al	NNP
cord-273487-nfgjz6f9	144	11	.	.	NNP
cord-273487-nfgjz6f9	144	12	,	,	,
cord-273487-nfgjz6f9	144	13	2010	2010	CD
cord-273487-nfgjz6f9	144	14	)	)	-RRB-
cord-273487-nfgjz6f9	144	15	.	.	.
cord-273487-nfgjz6f9	145	1	However	however	RB
cord-273487-nfgjz6f9	145	2	,	,	,
cord-273487-nfgjz6f9	145	3	because	because	IN
cord-273487-nfgjz6f9	145	4	coronaviruses	coronaviruse	NNS
cord-273487-nfgjz6f9	145	5	replicate	replicate	VBP
cord-273487-nfgjz6f9	145	6	in	in	IN
cord-273487-nfgjz6f9	145	7	the	the	DT
cord-273487-nfgjz6f9	145	8	cytoplasm	cytoplasm	NN
cord-273487-nfgjz6f9	145	9	,	,	,
cord-273487-nfgjz6f9	145	10	it	-PRON-	PRP
cord-273487-nfgjz6f9	145	11	would	would	MD
cord-273487-nfgjz6f9	145	12	appear	appear	VB
cord-273487-nfgjz6f9	145	13	that	that	IN
cord-273487-nfgjz6f9	145	14	the	the	DT
cord-273487-nfgjz6f9	145	15	role	role	NN
cord-273487-nfgjz6f9	145	16	DDX1	DDX1	NNP
cord-273487-nfgjz6f9	145	17	plays	play	VBZ
cord-273487-nfgjz6f9	145	18	in	in	IN
cord-273487-nfgjz6f9	145	19	replication	replication	NN
cord-273487-nfgjz6f9	145	20	of	of	IN
cord-273487-nfgjz6f9	145	21	these	these	DT
cord-273487-nfgjz6f9	145	22	large	large	JJ
cord-273487-nfgjz6f9	145	23	RNA	RNA	NNP
cord-273487-nfgjz6f9	145	24	viruses	virus	NNS
cord-273487-nfgjz6f9	145	25	is	be	VBZ
cord-273487-nfgjz6f9	145	26	distinct	distinct	JJ
cord-273487-nfgjz6f9	145	27	from	from	IN
cord-273487-nfgjz6f9	145	28	its	-PRON-	PRP$
cord-273487-nfgjz6f9	145	29	function	function	NN
cord-273487-nfgjz6f9	145	30	as	as	IN
cord-273487-nfgjz6f9	145	31	a	a	DT
cord-273487-nfgjz6f9	145	32	cofactor	cofactor	NN
cord-273487-nfgjz6f9	145	33	for	for	IN
cord-273487-nfgjz6f9	145	34	HIV	HIV	NNP
cord-273487-nfgjz6f9	145	35	.	.	.
cord-273487-nfgjz6f9	146	1	Yeast	yeast	NN
cord-273487-nfgjz6f9	146	2	two	two	CD
cord-273487-nfgjz6f9	146	3	hybrid	hybrid	NN
cord-273487-nfgjz6f9	146	4	and	and	CC
cord-273487-nfgjz6f9	146	5	RNA	RNA	NNP
cord-273487-nfgjz6f9	146	6	interference	interference	NN
cord-273487-nfgjz6f9	146	7	screens	screen	NNS
cord-273487-nfgjz6f9	146	8	have	have	VBP
cord-273487-nfgjz6f9	146	9	also	also	RB
cord-273487-nfgjz6f9	146	10	identified	identify	VBN
cord-273487-nfgjz6f9	146	11	DEAD	dead	JJ
cord-273487-nfgjz6f9	146	12	box	box	NN
cord-273487-nfgjz6f9	146	13	helicases	helicase	NNS
cord-273487-nfgjz6f9	146	14	that	that	WDT
cord-273487-nfgjz6f9	146	15	play	play	VBP
cord-273487-nfgjz6f9	146	16	significant	significant	JJ
cord-273487-nfgjz6f9	146	17	roles	role	NNS
cord-273487-nfgjz6f9	146	18	in	in	IN
cord-273487-nfgjz6f9	146	19	the	the	DT
cord-273487-nfgjz6f9	146	20	biology	biology	NN
cord-273487-nfgjz6f9	146	21	of	of	IN
cord-273487-nfgjz6f9	146	22	flavivirus	flavivirus	JJ
cord-273487-nfgjz6f9	146	23	infections	infection	NNS
cord-273487-nfgjz6f9	147	1	(	(	-LRB-
cord-273487-nfgjz6f9	147	2	Ariumi	Ariumi	NNP
cord-273487-nfgjz6f9	147	3	et	et	FW
cord-273487-nfgjz6f9	147	4	al	al	NNP
cord-273487-nfgjz6f9	147	5	.	.	.
cord-273487-nfgjz6f9	148	1	,	,	,
cord-273487-nfgjz6f9	148	2	2007	2007	CD
cord-273487-nfgjz6f9	148	3	;	;	:
cord-273487-nfgjz6f9	148	4	Krishnan	Krishnan	NNP
cord-273487-nfgjz6f9	148	5	et	et	NNP
cord-273487-nfgjz6f9	148	6	al	al	NNP
cord-273487-nfgjz6f9	148	7	.	.	NNP
cord-273487-nfgjz6f9	148	8	,	,	,
cord-273487-nfgjz6f9	148	9	2008	2008	CD
cord-273487-nfgjz6f9	148	10	;	;	:
cord-273487-nfgjz6f9	148	11	Mamiya	Mamiya	NNP
cord-273487-nfgjz6f9	148	12	and	and	CC
cord-273487-nfgjz6f9	148	13	Worman	Worman	NNP
cord-273487-nfgjz6f9	148	14	,	,	,
cord-273487-nfgjz6f9	148	15	1999	1999	CD
cord-273487-nfgjz6f9	148	16	)	)	-RRB-
cord-273487-nfgjz6f9	148	17	.	.	.
cord-273487-nfgjz6f9	149	1	Many	many	JJ
cord-273487-nfgjz6f9	149	2	of	of	IN
cord-273487-nfgjz6f9	149	3	these	these	DT
cord-273487-nfgjz6f9	149	4	enzymes	enzyme	NNS
cord-273487-nfgjz6f9	149	5	likely	likely	JJ
cord-273487-nfgjz6f9	149	6	function	function	VBP
cord-273487-nfgjz6f9	149	7	in	in	IN
cord-273487-nfgjz6f9	149	8	replication	replication	NN
cord-273487-nfgjz6f9	149	9	of	of	IN
cord-273487-nfgjz6f9	149	10	viral	viral	JJ
cord-273487-nfgjz6f9	149	11	RNA	RNA	NNP
cord-273487-nfgjz6f9	149	12	however	however	RB
cord-273487-nfgjz6f9	149	13	recent	recent	JJ
cord-273487-nfgjz6f9	149	14	evidence	evidence	NN
cord-273487-nfgjz6f9	149	15	suggests	suggest	VBZ
cord-273487-nfgjz6f9	149	16	that	that	IN
cord-273487-nfgjz6f9	149	17	helicases	helicase	NNS
cord-273487-nfgjz6f9	149	18	are	be	VBP
cord-273487-nfgjz6f9	149	19	needed	need	VBN
cord-273487-nfgjz6f9	149	20	for	for	IN
cord-273487-nfgjz6f9	149	21	efficient	efficient	JJ
cord-273487-nfgjz6f9	149	22	virus	virus	NN
cord-273487-nfgjz6f9	149	23	assembly	assembly	NN
cord-273487-nfgjz6f9	149	24	too	too	RB
cord-273487-nfgjz6f9	149	25	.	.	.
cord-273487-nfgjz6f9	150	1	For	for	IN
cord-273487-nfgjz6f9	150	2	example	example	NN
cord-273487-nfgjz6f9	150	3	,	,	,
cord-273487-nfgjz6f9	150	4	we	-PRON-	PRP
cord-273487-nfgjz6f9	150	5	recently	recently	RB
cord-273487-nfgjz6f9	150	6	determined	determine	VBD
cord-273487-nfgjz6f9	150	7	that	that	IN
cord-273487-nfgjz6f9	150	8	the	the	DT
cord-273487-nfgjz6f9	150	9	nucleolar	nucleolar	NN
cord-273487-nfgjz6f9	150	10	helicase	helicase	NNP
cord-273487-nfgjz6f9	150	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	150	12	is	be	VBZ
cord-273487-nfgjz6f9	150	13	needed	need	VBN
cord-273487-nfgjz6f9	150	14	for	for	IN
cord-273487-nfgjz6f9	150	15	a	a	DT
cord-273487-nfgjz6f9	150	16	critical	critical	JJ
cord-273487-nfgjz6f9	150	17	post	post	JJ
cord-273487-nfgjz6f9	150	18	-	-	JJ
cord-273487-nfgjz6f9	150	19	replication	replication	JJ
cord-273487-nfgjz6f9	150	20	step	step	NN
cord-273487-nfgjz6f9	150	21	in	in	IN
cord-273487-nfgjz6f9	150	22	WNV	WNV	NNP
cord-273487-nfgjz6f9	150	23	morphogenesis	morphogenesis	NN
cord-273487-nfgjz6f9	150	24	(	(	-LRB-
cord-273487-nfgjz6f9	150	25	Xu	Xu	NNP
cord-273487-nfgjz6f9	150	26	et	et	NNP
cord-273487-nfgjz6f9	150	27	al	al	NNP
cord-273487-nfgjz6f9	150	28	.	.	NNP
cord-273487-nfgjz6f9	150	29	,	,	,
cord-273487-nfgjz6f9	150	30	2011	2011	CD
cord-273487-nfgjz6f9	150	31	)	)	-RRB-
cord-273487-nfgjz6f9	150	32	.	.	.
cord-273487-nfgjz6f9	151	1	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	151	2	appears	appear	VBZ
cord-273487-nfgjz6f9	151	3	to	to	TO
cord-273487-nfgjz6f9	151	4	function	function	VB
cord-273487-nfgjz6f9	151	5	in	in	IN
cord-273487-nfgjz6f9	151	6	assembly	assembly	NN
cord-273487-nfgjz6f9	151	7	of	of	IN
cord-273487-nfgjz6f9	151	8	pre	pre	JJ
cord-273487-nfgjz6f9	151	9	-	-	JJ
cord-273487-nfgjz6f9	151	10	ribosomal	ribosomal	JJ
cord-273487-nfgjz6f9	151	11	particles	particle	NNS
cord-273487-nfgjz6f9	151	12	,	,	,
cord-273487-nfgjz6f9	151	13	but	but	CC
cord-273487-nfgjz6f9	151	14	it	-PRON-	PRP
cord-273487-nfgjz6f9	151	15	is	be	VBZ
cord-273487-nfgjz6f9	151	16	not	not	RB
cord-273487-nfgjz6f9	151	17	associated	associate	VBN
cord-273487-nfgjz6f9	151	18	with	with	IN
cord-273487-nfgjz6f9	151	19	mature	mature	JJ
cord-273487-nfgjz6f9	151	20	ribosomes	ribosome	NNS
cord-273487-nfgjz6f9	151	21	(	(	-LRB-
cord-273487-nfgjz6f9	151	22	Zirwes	Zirwes	NNP
cord-273487-nfgjz6f9	151	23	et	et	FW
cord-273487-nfgjz6f9	151	24	al	al	NNP
cord-273487-nfgjz6f9	151	25	.	.	NNP
cord-273487-nfgjz6f9	151	26	,	,	,
cord-273487-nfgjz6f9	151	27	2000	2000	CD
cord-273487-nfgjz6f9	151	28	)	)	-RRB-
cord-273487-nfgjz6f9	151	29	.	.	.
cord-273487-nfgjz6f9	152	1	By	by	IN
cord-273487-nfgjz6f9	152	2	analogy	analogy	NN
cord-273487-nfgjz6f9	152	3	,	,	,
cord-273487-nfgjz6f9	152	4	it	-PRON-	PRP
cord-273487-nfgjz6f9	152	5	is	be	VBZ
cord-273487-nfgjz6f9	152	6	tempting	tempt	VBG
cord-273487-nfgjz6f9	152	7	to	to	TO
cord-273487-nfgjz6f9	152	8	speculate	speculate	VB
cord-273487-nfgjz6f9	152	9	that	that	IN
cord-273487-nfgjz6f9	152	10	DDX56	ddx56	DT
cord-273487-nfgjz6f9	152	11	functions	function	NNS
cord-273487-nfgjz6f9	152	12	similarly	similarly	RB
cord-273487-nfgjz6f9	152	13	in	in	IN
cord-273487-nfgjz6f9	152	14	assembly	assembly	NN
cord-273487-nfgjz6f9	152	15	of	of	IN
cord-273487-nfgjz6f9	152	16	other	other	JJ
cord-273487-nfgjz6f9	152	17	large	large	JJ
cord-273487-nfgjz6f9	152	18	ribonucleoprotein	ribonucleoprotein	NN
cord-273487-nfgjz6f9	152	19	particles	particle	NNS
cord-273487-nfgjz6f9	152	20	such	such	JJ
cord-273487-nfgjz6f9	152	21	as	as	IN
cord-273487-nfgjz6f9	152	22	viral	viral	JJ
cord-273487-nfgjz6f9	152	23	nucleocapsids	nucleocapsid	NNS
cord-273487-nfgjz6f9	152	24	.	.	.
cord-273487-nfgjz6f9	153	1	The	the	DT
cord-273487-nfgjz6f9	153	2	fact	fact	NN
cord-273487-nfgjz6f9	153	3	that	that	IN
cord-273487-nfgjz6f9	153	4	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	153	5	is	be	VBZ
cord-273487-nfgjz6f9	153	6	not	not	RB
cord-273487-nfgjz6f9	153	7	detected	detect	VBN
cord-273487-nfgjz6f9	153	8	in	in	IN
cord-273487-nfgjz6f9	153	9	mature	mature	JJ
cord-273487-nfgjz6f9	153	10	WNV	WNV	NNP
cord-273487-nfgjz6f9	153	11	virions	virion	NNS
cord-273487-nfgjz6f9	153	12	(	(	-LRB-
cord-273487-nfgjz6f9	153	13	Xu	Xu	NNP
cord-273487-nfgjz6f9	153	14	et	et	NNP
cord-273487-nfgjz6f9	153	15	al	al	NNP
cord-273487-nfgjz6f9	153	16	.	.	NNP
cord-273487-nfgjz6f9	153	17	,	,	,
cord-273487-nfgjz6f9	153	18	2011	2011	CD
cord-273487-nfgjz6f9	153	19	)	)	-RRB-
cord-273487-nfgjz6f9	153	20	is	be	VBZ
cord-273487-nfgjz6f9	153	21	consistent	consistent	JJ
cord-273487-nfgjz6f9	153	22	with	with	IN
cord-273487-nfgjz6f9	153	23	this	this	DT
cord-273487-nfgjz6f9	153	24	scenario	scenario	NN
cord-273487-nfgjz6f9	153	25	.	.	.
cord-273487-nfgjz6f9	154	1	A	a	DT
cord-273487-nfgjz6f9	154	2	related	related	JJ
cord-273487-nfgjz6f9	154	3	study	study	NN
cord-273487-nfgjz6f9	154	4	by	by	IN
cord-273487-nfgjz6f9	154	5	another	another	DT
cord-273487-nfgjz6f9	154	6	laboratory	laboratory	NN
cord-273487-nfgjz6f9	154	7	revealed	reveal	VBD
cord-273487-nfgjz6f9	154	8	that	that	IN
cord-273487-nfgjz6f9	154	9	DDX24	DDX24	NNP
cord-273487-nfgjz6f9	154	10	performs	perform	VBZ
cord-273487-nfgjz6f9	154	11	a	a	DT
cord-273487-nfgjz6f9	154	12	similar	similar	JJ
cord-273487-nfgjz6f9	154	13	function	function	NN
cord-273487-nfgjz6f9	154	14	during	during	IN
cord-273487-nfgjz6f9	154	15	assembly	assembly	NN
cord-273487-nfgjz6f9	154	16	of	of	IN
cord-273487-nfgjz6f9	154	17	HIV	HIV	NNP
cord-273487-nfgjz6f9	154	18	virions	virion	NNS
cord-273487-nfgjz6f9	154	19	(	(	-LRB-
cord-273487-nfgjz6f9	154	20	Ma	Ma	NNP
cord-273487-nfgjz6f9	154	21	et	et	NNP
cord-273487-nfgjz6f9	154	22	al	al	NNP
cord-273487-nfgjz6f9	154	23	.	.	NNP
cord-273487-nfgjz6f9	154	24	,	,	,
cord-273487-nfgjz6f9	154	25	2008	2008	CD
cord-273487-nfgjz6f9	154	26	)	)	-RRB-
cord-273487-nfgjz6f9	154	27	.	.	.
cord-273487-nfgjz6f9	155	1	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	155	2	is	be	VBZ
cord-273487-nfgjz6f9	155	3	not	not	RB
cord-273487-nfgjz6f9	155	4	required	require	VBN
cord-273487-nfgjz6f9	155	5	for	for	IN
cord-273487-nfgjz6f9	155	6	viability	viability	NN
cord-273487-nfgjz6f9	155	7	of	of	IN
cord-273487-nfgjz6f9	155	8	cells	cell	NNS
cord-273487-nfgjz6f9	155	9	in	in	IN
cord-273487-nfgjz6f9	155	10	vitro	vitro	FW
cord-273487-nfgjz6f9	155	11	(	(	-LRB-
cord-273487-nfgjz6f9	156	1	Xu	Xu	NNP
cord-273487-nfgjz6f9	156	2	et	et	NNP
cord-273487-nfgjz6f9	156	3	al	al	NNP
cord-273487-nfgjz6f9	156	4	.	.	NNP
cord-273487-nfgjz6f9	156	5	,	,	,
cord-273487-nfgjz6f9	156	6	2011	2011	CD
cord-273487-nfgjz6f9	156	7	)	)	-RRB-
cord-273487-nfgjz6f9	156	8	and	and	CC
cord-273487-nfgjz6f9	157	1	therefore	therefore	RB
cord-273487-nfgjz6f9	157	2	,	,	,
cord-273487-nfgjz6f9	157	3	targeting	target	VBG
cord-273487-nfgjz6f9	157	4	the	the	DT
cord-273487-nfgjz6f9	157	5	activity	activity	NN
cord-273487-nfgjz6f9	157	6	of	of	IN
cord-273487-nfgjz6f9	157	7	this	this	DT
cord-273487-nfgjz6f9	157	8	enzyme	enzyme	NN
cord-273487-nfgjz6f9	157	9	could	could	MD
cord-273487-nfgjz6f9	157	10	prove	prove	VB
cord-273487-nfgjz6f9	157	11	beneficial	beneficial	JJ
cord-273487-nfgjz6f9	157	12	in	in	IN
cord-273487-nfgjz6f9	157	13	controlling	control	VBG
cord-273487-nfgjz6f9	157	14	WNV	WNV	NNP
cord-273487-nfgjz6f9	157	15	and	and	CC
cord-273487-nfgjz6f9	157	16	potentially	potentially	RB
cord-273487-nfgjz6f9	157	17	other	other	JJ
cord-273487-nfgjz6f9	157	18	flavivirus	flavivirus	JJ
cord-273487-nfgjz6f9	157	19	infections	infection	NNS
cord-273487-nfgjz6f9	157	20	.	.	.
cord-273487-nfgjz6f9	158	1	Rather	rather	RB
cord-273487-nfgjz6f9	158	2	than	than	IN
cord-273487-nfgjz6f9	158	3	using	use	VBG
cord-273487-nfgjz6f9	158	4	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	158	5	to	to	IN
cord-273487-nfgjz6f9	158	6	down	down	RB
cord-273487-nfgjz6f9	158	7	-	-	HYPH
cord-273487-nfgjz6f9	158	8	regulate	regulate	VB
cord-273487-nfgjz6f9	158	9	expression	expression	NN
cord-273487-nfgjz6f9	158	10	of	of	IN
cord-273487-nfgjz6f9	158	11	DDX56	ddx56	DT
cord-273487-nfgjz6f9	158	12	in	in	IN
cord-273487-nfgjz6f9	158	13	cells	cell	NNS
cord-273487-nfgjz6f9	158	14	,	,	,
cord-273487-nfgjz6f9	158	15	it	-PRON-	PRP
cord-273487-nfgjz6f9	158	16	would	would	MD
cord-273487-nfgjz6f9	158	17	be	be	VB
cord-273487-nfgjz6f9	158	18	advantageous	advantageous	JJ
cord-273487-nfgjz6f9	158	19	to	to	TO
cord-273487-nfgjz6f9	158	20	use	use	VB
cord-273487-nfgjz6f9	158	21	small	small	JJ
cord-273487-nfgjz6f9	158	22	molecule	molecule	NN
cord-273487-nfgjz6f9	158	23	inhibitors	inhibitor	NNS
cord-273487-nfgjz6f9	158	24	that	that	WDT
cord-273487-nfgjz6f9	158	25	target	target	VBP
cord-273487-nfgjz6f9	158	26	the	the	DT
cord-273487-nfgjz6f9	158	27	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	158	28	activity	activity	NN
cord-273487-nfgjz6f9	158	29	of	of	IN
cord-273487-nfgjz6f9	158	30	this	this	DT
cord-273487-nfgjz6f9	158	31	Fig	Fig	NNP
cord-273487-nfgjz6f9	158	32	.	.	NNP
cord-273487-nfgjz6f9	158	33	7	7	CD
cord-273487-nfgjz6f9	158	34	.	.	.
cord-273487-nfgjz6f9	159	1	Nucleolar	Nucleolar	NNP
cord-273487-nfgjz6f9	159	2	targeting	target	VBG
cord-273487-nfgjz6f9	159	3	information	information	NN
cord-273487-nfgjz6f9	159	4	of	of	IN
cord-273487-nfgjz6f9	159	5	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	159	6	is	be	VBZ
cord-273487-nfgjz6f9	159	7	contained	contain	VBN
cord-273487-nfgjz6f9	159	8	in	in	IN
cord-273487-nfgjz6f9	159	9	the	the	DT
cord-273487-nfgjz6f9	159	10	C	C	NNP
cord-273487-nfgjz6f9	159	11	-	-	HYPH
cord-273487-nfgjz6f9	159	12	terminal	terminal	NN
cord-273487-nfgjz6f9	159	13	329	329	CD
cord-273487-nfgjz6f9	159	14	amino	amino	NN
cord-273487-nfgjz6f9	159	15	acid	acid	NN
cord-273487-nfgjz6f9	159	16	residues	residue	NNS
cord-273487-nfgjz6f9	159	17	.	.	.
cord-273487-nfgjz6f9	160	1	A549	a549	JJ
cord-273487-nfgjz6f9	160	2	cells	cell	NNS
cord-273487-nfgjz6f9	160	3	were	be	VBD
cord-273487-nfgjz6f9	160	4	transfected	transfecte	VBN
cord-273487-nfgjz6f9	160	5	with	with	IN
cord-273487-nfgjz6f9	160	6	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	160	7	encoding	encode	VBG
cord-273487-nfgjz6f9	160	8	myc	myc	NNP
cord-273487-nfgjz6f9	160	9	-	-	HYPH
cord-273487-nfgjz6f9	160	10	tagged	tag	VBN
cord-273487-nfgjz6f9	160	11	wild	wild	JJ
cord-273487-nfgjz6f9	160	12	type	type	NN
cord-273487-nfgjz6f9	160	13	(	(	-LRB-
cord-273487-nfgjz6f9	160	14	WT	WT	NNP
cord-273487-nfgjz6f9	160	15	)	)	-RRB-
cord-273487-nfgjz6f9	161	1	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	161	2	,	,	,
cord-273487-nfgjz6f9	161	3	DDX56-NT	DDX56-NT	NNP
cord-273487-nfgjz6f9	161	4	or	or	CC
cord-273487-nfgjz6f9	161	5	DDX56-CT	DDX56-CT	NNP
cord-273487-nfgjz6f9	161	6	.	.	.
cord-273487-nfgjz6f9	162	1	Twenty	twenty	CD
cord-273487-nfgjz6f9	162	2	-	-	HYPH
cord-273487-nfgjz6f9	162	3	four	four	CD
cord-273487-nfgjz6f9	162	4	hours	hour	NNS
cord-273487-nfgjz6f9	162	5	post	post	NN
cord-273487-nfgjz6f9	162	6	-	-	NN
cord-273487-nfgjz6f9	162	7	transfection	transfection	JJ
cord-273487-nfgjz6f9	162	8	,	,	,
cord-273487-nfgjz6f9	162	9	cells	cell	NNS
cord-273487-nfgjz6f9	162	10	were	be	VBD
cord-273487-nfgjz6f9	162	11	infected	infect	VBN
cord-273487-nfgjz6f9	162	12	with	with	IN
cord-273487-nfgjz6f9	162	13	WNV	WNV	NNP
cord-273487-nfgjz6f9	162	14	(	(	-LRB-
cord-273487-nfgjz6f9	162	15	MOI	MOI	NNP
cord-273487-nfgjz6f9	162	16	¼	¼	NNP
cord-273487-nfgjz6f9	162	17	5	5	CD
cord-273487-nfgjz6f9	162	18	)	)	-RRB-
cord-273487-nfgjz6f9	162	19	for	for	IN
cord-273487-nfgjz6f9	162	20	24	24	CD
cord-273487-nfgjz6f9	162	21	h	h	NN
cord-273487-nfgjz6f9	162	22	and	and	CC
cord-273487-nfgjz6f9	162	23	then	then	RB
cord-273487-nfgjz6f9	162	24	fixed	fix	VBN
cord-273487-nfgjz6f9	162	25	and	and	CC
cord-273487-nfgjz6f9	162	26	processed	process	VBN
cord-273487-nfgjz6f9	162	27	for	for	IN
cord-273487-nfgjz6f9	162	28	indirect	indirect	JJ
cord-273487-nfgjz6f9	162	29	immunofluorescence	immunofluorescence	NN
cord-273487-nfgjz6f9	162	30	using	use	VBG
cord-273487-nfgjz6f9	162	31	mouse	mouse	NN
cord-273487-nfgjz6f9	162	32	anti	anti	NNP
cord-273487-nfgjz6f9	162	33	-	-	NNP
cord-273487-nfgjz6f9	162	34	myc	myc	JJ
cord-273487-nfgjz6f9	162	35	,	,	,
cord-273487-nfgjz6f9	162	36	rabbit	rabbit	NN
cord-273487-nfgjz6f9	162	37	anti	anti	NNP
cord-273487-nfgjz6f9	162	38	-	-	JJ
cord-273487-nfgjz6f9	162	39	nucleolin	nucleolin	JJ
cord-273487-nfgjz6f9	162	40	,	,	,
cord-273487-nfgjz6f9	162	41	and	and	CC
cord-273487-nfgjz6f9	162	42	guinea	guinea	NNP
cord-273487-nfgjz6f9	162	43	pig	pig	NNP
cord-273487-nfgjz6f9	162	44	anti	anti	NNP
cord-273487-nfgjz6f9	162	45	-	-	NNP
cord-273487-nfgjz6f9	162	46	WNV	WNV	NNP
cord-273487-nfgjz6f9	162	47	capsid	capsid	NN
cord-273487-nfgjz6f9	162	48	antibodies	antibody	NNS
cord-273487-nfgjz6f9	162	49	.	.	.
cord-273487-nfgjz6f9	163	1	Primary	primary	JJ
cord-273487-nfgjz6f9	163	2	antibodies	antibody	NNS
cord-273487-nfgjz6f9	163	3	were	be	VBD
cord-273487-nfgjz6f9	163	4	detected	detect	VBN
cord-273487-nfgjz6f9	163	5	using	use	VBG
cord-273487-nfgjz6f9	163	6	donkey	donkey	NN
cord-273487-nfgjz6f9	163	7	anti	anti	JJ
cord-273487-nfgjz6f9	163	8	-	-	JJ
cord-273487-nfgjz6f9	163	9	mouse	mouse	NN
cord-273487-nfgjz6f9	163	10	Alexa546	Alexa546	NNP
cord-273487-nfgjz6f9	163	11	,	,	,
cord-273487-nfgjz6f9	163	12	donkey	donkey	JJ
cord-273487-nfgjz6f9	163	13	anti	anti	JJ
cord-273487-nfgjz6f9	163	14	-	-	JJ
cord-273487-nfgjz6f9	163	15	rabbit	rabbit	NN
cord-273487-nfgjz6f9	163	16	Alexa647	Alexa647	NNP
cord-273487-nfgjz6f9	163	17	and	and	CC
cord-273487-nfgjz6f9	163	18	goat	goat	NNP
cord-273487-nfgjz6f9	163	19	anti	anti	JJ
cord-273487-nfgjz6f9	163	20	-	-	JJ
cord-273487-nfgjz6f9	163	21	guinea	guinea	JJ
cord-273487-nfgjz6f9	163	22	pig	pig	NN
cord-273487-nfgjz6f9	163	23	Alexa488	Alexa488	NNP
cord-273487-nfgjz6f9	163	24	secondary	secondary	JJ
cord-273487-nfgjz6f9	163	25	antibodies	antibody	NNS
cord-273487-nfgjz6f9	163	26	.	.	.
cord-273487-nfgjz6f9	164	1	Arrowheads	arrowhead	NNS
cord-273487-nfgjz6f9	164	2	indicate	indicate	VBP
cord-273487-nfgjz6f9	164	3	colocalization	colocalization	NN
cord-273487-nfgjz6f9	164	4	between	between	IN
cord-273487-nfgjz6f9	164	5	capsid	capsid	NN
cord-273487-nfgjz6f9	164	6	,	,	,
cord-273487-nfgjz6f9	164	7	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	164	8	constructs	construct	NNS
cord-273487-nfgjz6f9	164	9	and	and	CC
cord-273487-nfgjz6f9	164	10	the	the	DT
cord-273487-nfgjz6f9	164	11	nucleolar	nucleolar	JJ
cord-273487-nfgjz6f9	164	12	resident	resident	NN
cord-273487-nfgjz6f9	164	13	protein	protein	NN
cord-273487-nfgjz6f9	164	14	nucleolin	nucleolin	NNP
cord-273487-nfgjz6f9	164	15	.	.	.
cord-273487-nfgjz6f9	165	1	Nuclei	nucleus	NNS
cord-273487-nfgjz6f9	165	2	are	be	VBP
cord-273487-nfgjz6f9	165	3	stained	stain	VBN
cord-273487-nfgjz6f9	165	4	with	with	IN
cord-273487-nfgjz6f9	165	5	DAPI	DAPI	NNP
cord-273487-nfgjz6f9	165	6	.	.	.
cord-273487-nfgjz6f9	166	1	Images	image	NNS
cord-273487-nfgjz6f9	166	2	were	be	VBD
cord-273487-nfgjz6f9	166	3	captured	capture	VBN
cord-273487-nfgjz6f9	166	4	using	use	VBG
cord-273487-nfgjz6f9	166	5	a	a	DT
cord-273487-nfgjz6f9	166	6	leica	leica	NNP
cord-273487-nfgjz6f9	166	7	TCS	TCS	NNP
cord-273487-nfgjz6f9	166	8	SP5	SP5	NNP
cord-273487-nfgjz6f9	166	9	confocal	confocal	JJ
cord-273487-nfgjz6f9	166	10	scanning	scanning	NN
cord-273487-nfgjz6f9	166	11	microscope	microscope	NN
cord-273487-nfgjz6f9	166	12	.	.	.
cord-273487-nfgjz6f9	167	1	Size	size	NN
cord-273487-nfgjz6f9	167	2	bar	bar	NN
cord-273487-nfgjz6f9	167	3	¼10	¼10	NN
cord-273487-nfgjz6f9	167	4	mm	mm	NN
cord-273487-nfgjz6f9	167	5	.	.	.
cord-273487-nfgjz6f9	168	1	protein	protein	NNP
cord-273487-nfgjz6f9	168	2	.	.	.
cord-273487-nfgjz6f9	169	1	If	if	IN
cord-273487-nfgjz6f9	169	2	this	this	DT
cord-273487-nfgjz6f9	169	3	is	be	VBZ
cord-273487-nfgjz6f9	169	4	to	to	TO
cord-273487-nfgjz6f9	169	5	be	be	VB
cord-273487-nfgjz6f9	169	6	a	a	DT
cord-273487-nfgjz6f9	169	7	feasible	feasible	JJ
cord-273487-nfgjz6f9	169	8	approach	approach	NN
cord-273487-nfgjz6f9	169	9	,	,	,
cord-273487-nfgjz6f9	169	10	it	-PRON-	PRP
cord-273487-nfgjz6f9	169	11	was	be	VBD
cord-273487-nfgjz6f9	169	12	important	important	JJ
cord-273487-nfgjz6f9	169	13	to	to	TO
cord-273487-nfgjz6f9	169	14	demonstrate	demonstrate	VB
cord-273487-nfgjz6f9	169	15	that	that	IN
cord-273487-nfgjz6f9	169	16	the	the	DT
cord-273487-nfgjz6f9	169	17	helicase	helicase	NN
cord-273487-nfgjz6f9	169	18	activity	activity	NN
cord-273487-nfgjz6f9	169	19	of	of	IN
cord-273487-nfgjz6f9	169	20	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	169	21	is	be	VBZ
cord-273487-nfgjz6f9	169	22	in	in	IN
cord-273487-nfgjz6f9	169	23	fact	fact	NN
cord-273487-nfgjz6f9	169	24	required	require	VBN
cord-273487-nfgjz6f9	169	25	for	for	IN
cord-273487-nfgjz6f9	169	26	its	-PRON-	PRP$
cord-273487-nfgjz6f9	169	27	role	role	NN
cord-273487-nfgjz6f9	169	28	in	in	IN
cord-273487-nfgjz6f9	169	29	WNV	WNV	NNP
cord-273487-nfgjz6f9	169	30	infectivity	infectivity	NN
cord-273487-nfgjz6f9	169	31	.	.	.
cord-273487-nfgjz6f9	170	1	While	while	IN
cord-273487-nfgjz6f9	170	2	this	this	DT
cord-273487-nfgjz6f9	170	3	may	may	MD
cord-273487-nfgjz6f9	170	4	seem	seem	VB
cord-273487-nfgjz6f9	170	5	intuitive	intuitive	JJ
cord-273487-nfgjz6f9	170	6	,	,	,
cord-273487-nfgjz6f9	170	7	the	the	DT
cord-273487-nfgjz6f9	170	8	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	170	9	function	function	NN
cord-273487-nfgjz6f9	170	10	of	of	IN
cord-273487-nfgjz6f9	170	11	a	a	DT
cord-273487-nfgjz6f9	170	12	'	'	''
cord-273487-nfgjz6f9	170	13	'	'	``
cord-273487-nfgjz6f9	170	14	helicase	helicase	NN
cord-273487-nfgjz6f9	170	15	'	'	''
cord-273487-nfgjz6f9	170	16	'	'	''
cord-273487-nfgjz6f9	170	17	is	be	VBZ
cord-273487-nfgjz6f9	170	18	not	not	RB
cord-273487-nfgjz6f9	170	19	always	always	RB
cord-273487-nfgjz6f9	170	20	required	require	VBN
cord-273487-nfgjz6f9	170	21	for	for	IN
cord-273487-nfgjz6f9	170	22	its	-PRON-	PRP$
cord-273487-nfgjz6f9	170	23	role	role	NN
cord-273487-nfgjz6f9	170	24	in	in	IN
cord-273487-nfgjz6f9	170	25	virus	virus	NN
cord-273487-nfgjz6f9	170	26	biology	biology	NN
cord-273487-nfgjz6f9	170	27	.	.	.
cord-273487-nfgjz6f9	171	1	Indeed	indeed	RB
cord-273487-nfgjz6f9	171	2	,	,	,
cord-273487-nfgjz6f9	171	3	among	among	IN
cord-273487-nfgjz6f9	171	4	highly	highly	RB
cord-273487-nfgjz6f9	171	5	related	related	JJ
cord-273487-nfgjz6f9	171	6	viral	viral	JJ
cord-273487-nfgjz6f9	171	7	helicases	helicase	NNS
cord-273487-nfgjz6f9	171	8	,	,	,
cord-273487-nfgjz6f9	171	9	the	the	DT
cord-273487-nfgjz6f9	171	10	mode	mode	NN
cord-273487-nfgjz6f9	171	11	of	of	IN
cord-273487-nfgjz6f9	171	12	action	action	NN
cord-273487-nfgjz6f9	171	13	during	during	IN
cord-273487-nfgjz6f9	171	14	virus	virus	NN
cord-273487-nfgjz6f9	171	15	assembly	assembly	NN
cord-273487-nfgjz6f9	171	16	can	can	MD
cord-273487-nfgjz6f9	171	17	vary	vary	VB
cord-273487-nfgjz6f9	171	18	greatly	greatly	RB
cord-273487-nfgjz6f9	171	19	.	.	.
cord-273487-nfgjz6f9	172	1	For	for	IN
cord-273487-nfgjz6f9	172	2	example	example	NN
cord-273487-nfgjz6f9	172	3	,	,	,
cord-273487-nfgjz6f9	172	4	assembly	assembly	NN
cord-273487-nfgjz6f9	172	5	of	of	IN
cord-273487-nfgjz6f9	172	6	infectious	infectious	JJ
cord-273487-nfgjz6f9	172	7	Kunjin	Kunjin	NNP
cord-273487-nfgjz6f9	172	8	virus	virus	NN
cord-273487-nfgjz6f9	172	9	,	,	,
cord-273487-nfgjz6f9	172	10	a	a	DT
cord-273487-nfgjz6f9	172	11	close	close	JJ
cord-273487-nfgjz6f9	172	12	relative	relative	NN
cord-273487-nfgjz6f9	172	13	of	of	IN
cord-273487-nfgjz6f9	172	14	WNV	WNV	NNP
cord-273487-nfgjz6f9	172	15	,	,	,
cord-273487-nfgjz6f9	172	16	requires	require	VBZ
cord-273487-nfgjz6f9	172	17	expression	expression	NN
cord-273487-nfgjz6f9	172	18	of	of	IN
cord-273487-nfgjz6f9	172	19	the	the	DT
cord-273487-nfgjz6f9	172	20	viral	viral	JJ
cord-273487-nfgjz6f9	172	21	NS3	ns3	RB
cord-273487-nfgjz6f9	172	22	protein	protein	VBP
cord-273487-nfgjz6f9	172	23	in	in	IN
cord-273487-nfgjz6f9	172	24	cis	cis	NNP
cord-273487-nfgjz6f9	172	25	(	(	-LRB-
cord-273487-nfgjz6f9	172	26	Liu	Liu	NNP
cord-273487-nfgjz6f9	172	27	et	et	NNP
cord-273487-nfgjz6f9	172	28	al	al	NNP
cord-273487-nfgjz6f9	172	29	.	.	NNP
cord-273487-nfgjz6f9	172	30	,	,	,
cord-273487-nfgjz6f9	172	31	2002	2002	CD
cord-273487-nfgjz6f9	172	32	)	)	-RRB-
cord-273487-nfgjz6f9	172	33	.	.	.
cord-273487-nfgjz6f9	173	1	In	in	IN
cord-273487-nfgjz6f9	173	2	contrast	contrast	NN
cord-273487-nfgjz6f9	173	3	,	,	,
cord-273487-nfgjz6f9	173	4	during	during	IN
cord-273487-nfgjz6f9	173	5	assembly	assembly	NN
cord-273487-nfgjz6f9	173	6	of	of	IN
cord-273487-nfgjz6f9	173	7	yellow	yellow	JJ
cord-273487-nfgjz6f9	173	8	fever	fever	NN
cord-273487-nfgjz6f9	173	9	virus	virus	NN
cord-273487-nfgjz6f9	173	10	particles	particle	NNS
cord-273487-nfgjz6f9	173	11	,	,	,
cord-273487-nfgjz6f9	173	12	the	the	DT
cord-273487-nfgjz6f9	173	13	helicase	helicase	NN
cord-273487-nfgjz6f9	173	14	activity	activity	NN
cord-273487-nfgjz6f9	173	15	of	of	IN
cord-273487-nfgjz6f9	173	16	NS3	ns3	RB
cord-273487-nfgjz6f9	173	17	is	be	VBZ
cord-273487-nfgjz6f9	173	18	not	not	RB
cord-273487-nfgjz6f9	173	19	required	require	VBN
cord-273487-nfgjz6f9	173	20	for	for	IN
cord-273487-nfgjz6f9	173	21	this	this	DT
cord-273487-nfgjz6f9	173	22	process	process	NN
cord-273487-nfgjz6f9	173	23	(	(	-LRB-
cord-273487-nfgjz6f9	173	24	Patkar	Patkar	NNP
cord-273487-nfgjz6f9	173	25	and	and	CC
cord-273487-nfgjz6f9	173	26	Kuhn	Kuhn	NNP
cord-273487-nfgjz6f9	173	27	,	,	,
cord-273487-nfgjz6f9	173	28	2008	2008	CD
cord-273487-nfgjz6f9	173	29	)	)	-RRB-
cord-273487-nfgjz6f9	173	30	.	.	.
cord-273487-nfgjz6f9	174	1	Moreover	moreover	RB
cord-273487-nfgjz6f9	174	2	,	,	,
cord-273487-nfgjz6f9	174	3	yellow	yellow	JJ
cord-273487-nfgjz6f9	174	4	fever	fever	NN
cord-273487-nfgjz6f9	174	5	virus	virus	NN
cord-273487-nfgjz6f9	174	6	NS3	ns3	RB
cord-273487-nfgjz6f9	174	7	can	can	MD
cord-273487-nfgjz6f9	174	8	perform	perform	VB
cord-273487-nfgjz6f9	174	9	its	-PRON-	PRP$
cord-273487-nfgjz6f9	174	10	virus	virus	NN
cord-273487-nfgjz6f9	174	11	assembly	assembly	NN
cord-273487-nfgjz6f9	174	12	function	function	NN
cord-273487-nfgjz6f9	174	13	when	when	WRB
cord-273487-nfgjz6f9	174	14	expressed	express	VBN
cord-273487-nfgjz6f9	174	15	in	in	IN
cord-273487-nfgjz6f9	174	16	trans	trans	NNP
cord-273487-nfgjz6f9	174	17	unlike	unlike	IN
cord-273487-nfgjz6f9	174	18	Kunjin	Kunjin	NNP
cord-273487-nfgjz6f9	174	19	virus	virus	NN
cord-273487-nfgjz6f9	174	20	NS3	ns3	RB
cord-273487-nfgjz6f9	174	21	which	which	WDT
cord-273487-nfgjz6f9	174	22	must	must	MD
cord-273487-nfgjz6f9	174	23	be	be	VB
cord-273487-nfgjz6f9	174	24	expressed	express	VBN
cord-273487-nfgjz6f9	174	25	in	in	IN
cord-273487-nfgjz6f9	174	26	cis	cis	NNP
cord-273487-nfgjz6f9	174	27	.	.	.
cord-273487-nfgjz6f9	175	1	The	the	DT
cord-273487-nfgjz6f9	175	2	helicase	helicase	NN
cord-273487-nfgjz6f9	175	3	activity	activity	NN
cord-273487-nfgjz6f9	175	4	of	of	IN
cord-273487-nfgjz6f9	175	5	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	175	6	is	be	VBZ
cord-273487-nfgjz6f9	175	7	not	not	RB
cord-273487-nfgjz6f9	175	8	essential	essential	JJ
cord-273487-nfgjz6f9	175	9	for	for	IN
cord-273487-nfgjz6f9	175	10	replication	replication	NN
cord-273487-nfgjz6f9	175	11	or	or	CC
cord-273487-nfgjz6f9	175	12	assembly	assembly	NN
cord-273487-nfgjz6f9	175	13	of	of	IN
cord-273487-nfgjz6f9	175	14	WNV	WNV	NNP
cord-273487-nfgjz6f9	175	15	virions	virion	NNS
cord-273487-nfgjz6f9	175	16	per	per	IN
cord-273487-nfgjz6f9	175	17	se	se	FW
cord-273487-nfgjz6f9	175	18	but	but	CC
cord-273487-nfgjz6f9	175	19	our	-PRON-	PRP$
cord-273487-nfgjz6f9	175	20	data	datum	NNS
cord-273487-nfgjz6f9	175	21	indicate	indicate	VBP
cord-273487-nfgjz6f9	175	22	that	that	IN
cord-273487-nfgjz6f9	175	23	it	-PRON-	PRP
cord-273487-nfgjz6f9	175	24	is	be	VBZ
cord-273487-nfgjz6f9	175	25	critical	critical	JJ
cord-273487-nfgjz6f9	175	26	for	for	IN
cord-273487-nfgjz6f9	175	27	infectivity	infectivity	NN
cord-273487-nfgjz6f9	175	28	of	of	IN
cord-273487-nfgjz6f9	175	29	virus	virus	NN
cord-273487-nfgjz6f9	175	30	particles	particle	NNS
cord-273487-nfgjz6f9	175	31	.	.	.
cord-273487-nfgjz6f9	176	1	Moreover	moreover	RB
cord-273487-nfgjz6f9	176	2	,	,	,
cord-273487-nfgjz6f9	176	3	because	because	IN
cord-273487-nfgjz6f9	176	4	overexpression	overexpression	NN
cord-273487-nfgjz6f9	176	5	of	of	IN
cord-273487-nfgjz6f9	176	6	the	the	DT
cord-273487-nfgjz6f9	176	7	capsid	capsid	RB
cord-273487-nfgjz6f9	176	8	-	-	HYPH
cord-273487-nfgjz6f9	176	9	binding	bind	VBG
cord-273487-nfgjz6f9	176	10	region	region	NN
cord-273487-nfgjz6f9	176	11	of	of	IN
cord-273487-nfgjz6f9	176	12	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	176	13	has	have	VBZ
cord-273487-nfgjz6f9	176	14	a	a	DT
cord-273487-nfgjz6f9	176	15	similar	similar	JJ
cord-273487-nfgjz6f9	176	16	effect	effect	NN
cord-273487-nfgjz6f9	176	17	as	as	IN
cord-273487-nfgjz6f9	176	18	reducing	reduce	VBG
cord-273487-nfgjz6f9	176	19	expression	expression	NN
cord-273487-nfgjz6f9	176	20	of	of	IN
cord-273487-nfgjz6f9	176	21	DDX56	ddx56	DT
cord-273487-nfgjz6f9	176	22	or	or	CC
cord-273487-nfgjz6f9	176	23	knocking	knock	VBG
cord-273487-nfgjz6f9	176	24	out	out	RP
cord-273487-nfgjz6f9	176	25	its	-PRON-	PRP$
cord-273487-nfgjz6f9	176	26	helicase	helicase	NN
cord-273487-nfgjz6f9	176	27	activity	activity	NN
cord-273487-nfgjz6f9	176	28	,	,	,
cord-273487-nfgjz6f9	176	29	we	-PRON-	PRP
cord-273487-nfgjz6f9	176	30	hypothesize	hypothesize	VBP
cord-273487-nfgjz6f9	176	31	that	that	IN
cord-273487-nfgjz6f9	176	32	interaction	interaction	NN
cord-273487-nfgjz6f9	176	33	between	between	IN
cord-273487-nfgjz6f9	176	34	capsid	capsid	NN
cord-273487-nfgjz6f9	176	35	and	and	CC
cord-273487-nfgjz6f9	176	36	this	this	DT
cord-273487-nfgjz6f9	176	37	host	host	NN
cord-273487-nfgjz6f9	176	38	enzyme	enzyme	NN
cord-273487-nfgjz6f9	176	39	facilitate	facilitate	VBP
cord-273487-nfgjz6f9	176	40	loading	loading	NN
cord-273487-nfgjz6f9	176	41	and/or	and/or	CC
cord-273487-nfgjz6f9	176	42	organization	organization	NN
cord-273487-nfgjz6f9	176	43	of	of	IN
cord-273487-nfgjz6f9	176	44	viral	viral	JJ
cord-273487-nfgjz6f9	176	45	RNA	RNA	NNP
cord-273487-nfgjz6f9	176	46	during	during	IN
cord-273487-nfgjz6f9	176	47	virus	virus	NN
cord-273487-nfgjz6f9	176	48	assembly	assembly	NN
cord-273487-nfgjz6f9	176	49	.	.	.
cord-273487-nfgjz6f9	177	1	Through	through	IN
cord-273487-nfgjz6f9	177	2	an	an	DT
cord-273487-nfgjz6f9	177	3	unknown	unknown	JJ
cord-273487-nfgjz6f9	177	4	mechanism	mechanism	NN
cord-273487-nfgjz6f9	177	5	,	,	,
cord-273487-nfgjz6f9	177	6	WNV	WNV	NNP
cord-273487-nfgjz6f9	177	7	infection	infection	NN
cord-273487-nfgjz6f9	177	8	causes	cause	VBZ
cord-273487-nfgjz6f9	177	9	relocalization	relocalization	NN
cord-273487-nfgjz6f9	177	10	of	of	IN
cord-273487-nfgjz6f9	177	11	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	177	12	from	from	IN
cord-273487-nfgjz6f9	177	13	the	the	DT
cord-273487-nfgjz6f9	177	14	nucleolus	nucleolus	NN
cord-273487-nfgjz6f9	177	15	to	to	IN
cord-273487-nfgjz6f9	177	16	cytoplasmic	cytoplasmic	JJ
cord-273487-nfgjz6f9	177	17	structures	structure	NNS
cord-273487-nfgjz6f9	177	18	that	that	WDT
cord-273487-nfgjz6f9	177	19	are	be	VBP
cord-273487-nfgjz6f9	177	20	enriched	enrich	VBN
cord-273487-nfgjz6f9	177	21	in	in	IN
cord-273487-nfgjz6f9	177	22	capsid	capsid	NN
cord-273487-nfgjz6f9	177	23	protein	protein	NN
cord-273487-nfgjz6f9	177	24	(	(	-LRB-
cord-273487-nfgjz6f9	177	25	Xu	Xu	NNP
cord-273487-nfgjz6f9	177	26	et	et	NNP
cord-273487-nfgjz6f9	177	27	al	al	NNP
cord-273487-nfgjz6f9	177	28	.	.	NNP
cord-273487-nfgjz6f9	177	29	,	,	,
cord-273487-nfgjz6f9	177	30	2011	2011	CD
cord-273487-nfgjz6f9	177	31	)	)	-RRB-
cord-273487-nfgjz6f9	177	32	.	.	.
cord-273487-nfgjz6f9	178	1	It	-PRON-	PRP
cord-273487-nfgjz6f9	178	2	is	be	VBZ
cord-273487-nfgjz6f9	178	3	likely	likely	JJ
cord-273487-nfgjz6f9	178	4	that	that	IN
cord-273487-nfgjz6f9	178	5	these	these	DT
cord-273487-nfgjz6f9	178	6	capsid	capsid	RB
cord-273487-nfgjz6f9	178	7	-	-	HYPH
cord-273487-nfgjz6f9	178	8	positive	positive	JJ
cord-273487-nfgjz6f9	178	9	cytoplasmic	cytoplasmic	JJ
cord-273487-nfgjz6f9	178	10	elements	element	NNS
cord-273487-nfgjz6f9	178	11	are	be	VBP
cord-273487-nfgjz6f9	178	12	virus	virus	NN
cord-273487-nfgjz6f9	178	13	assembly	assembly	NN
cord-273487-nfgjz6f9	178	14	sites	site	NNS
cord-273487-nfgjz6f9	178	15	on	on	IN
cord-273487-nfgjz6f9	178	16	the	the	DT
cord-273487-nfgjz6f9	178	17	endoplasmic	endoplasmic	NN
cord-273487-nfgjz6f9	178	18	reticulum	reticulum	NN
cord-273487-nfgjz6f9	178	19	.	.	.
cord-273487-nfgjz6f9	179	1	Next	next	RB
cord-273487-nfgjz6f9	179	2	,	,	,
cord-273487-nfgjz6f9	179	3	it	-PRON-	PRP
cord-273487-nfgjz6f9	179	4	will	will	MD
cord-273487-nfgjz6f9	179	5	be	be	VB
cord-273487-nfgjz6f9	179	6	of	of	IN
cord-273487-nfgjz6f9	179	7	interest	interest	NN
cord-273487-nfgjz6f9	179	8	to	to	TO
cord-273487-nfgjz6f9	179	9	develop	develop	VB
cord-273487-nfgjz6f9	179	10	small	small	JJ
cord-273487-nfgjz6f9	179	11	molecule	molecule	NN
cord-273487-nfgjz6f9	179	12	inhibitors	inhibitor	NNS
cord-273487-nfgjz6f9	179	13	that	that	WDT
cord-273487-nfgjz6f9	179	14	can	can	MD
cord-273487-nfgjz6f9	179	15	be	be	VB
cord-273487-nfgjz6f9	179	16	used	use	VBN
cord-273487-nfgjz6f9	179	17	to	to	TO
cord-273487-nfgjz6f9	179	18	target	target	VB
cord-273487-nfgjz6f9	179	19	the	the	DT
cord-273487-nfgjz6f9	179	20	helicase	helicase	NN
cord-273487-nfgjz6f9	179	21	activity	activity	NN
cord-273487-nfgjz6f9	179	22	of	of	IN
cord-273487-nfgjz6f9	179	23	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	179	24	.	.	.
cord-273487-nfgjz6f9	180	1	These	these	DT
cord-273487-nfgjz6f9	180	2	inhibitors	inhibitor	NNS
cord-273487-nfgjz6f9	180	3	would	would	MD
cord-273487-nfgjz6f9	180	4	not	not	RB
cord-273487-nfgjz6f9	180	5	be	be	VB
cord-273487-nfgjz6f9	180	6	expected	expect	VBN
cord-273487-nfgjz6f9	180	7	to	to	TO
cord-273487-nfgjz6f9	180	8	block	block	VB
cord-273487-nfgjz6f9	180	9	replication	replication	NN
cord-273487-nfgjz6f9	180	10	of	of	IN
cord-273487-nfgjz6f9	180	11	WNV	WNV	NNP
cord-273487-nfgjz6f9	180	12	,	,	,
cord-273487-nfgjz6f9	180	13	but	but	CC
cord-273487-nfgjz6f9	180	14	by	by	IN
cord-273487-nfgjz6f9	180	15	reducing	reduce	VBG
cord-273487-nfgjz6f9	180	16	the	the	DT
cord-273487-nfgjz6f9	180	17	infectivity	infectivity	NN
cord-273487-nfgjz6f9	180	18	of	of	IN
cord-273487-nfgjz6f9	180	19	nascent	nascent	JJ
cord-273487-nfgjz6f9	180	20	virions	virion	NNS
cord-273487-nfgjz6f9	180	21	,	,	,
cord-273487-nfgjz6f9	180	22	viral	viral	JJ
cord-273487-nfgjz6f9	180	23	spread	spread	NN
cord-273487-nfgjz6f9	180	24	would	would	MD
cord-273487-nfgjz6f9	180	25	be	be	VB
cord-273487-nfgjz6f9	180	26	minimized	minimize	VBN
cord-273487-nfgjz6f9	180	27	thereby	thereby	RB
cord-273487-nfgjz6f9	180	28	allowing	allow	VBG
cord-273487-nfgjz6f9	180	29	the	the	DT
cord-273487-nfgjz6f9	180	30	immune	immune	JJ
cord-273487-nfgjz6f9	180	31	system	system	NN
cord-273487-nfgjz6f9	180	32	to	to	TO
cord-273487-nfgjz6f9	180	33	contain	contain	VB
cord-273487-nfgjz6f9	180	34	the	the	DT
cord-273487-nfgjz6f9	180	35	infection	infection	NN
cord-273487-nfgjz6f9	180	36	.	.	.
cord-273487-nfgjz6f9	181	1	Laboratory	laboratory	NN
cord-273487-nfgjz6f9	181	2	reagents	reagent	NNS
cord-273487-nfgjz6f9	181	3	were	be	VBD
cord-273487-nfgjz6f9	181	4	purchased	purchase	VBN
cord-273487-nfgjz6f9	181	5	from	from	IN
cord-273487-nfgjz6f9	181	6	the	the	DT
cord-273487-nfgjz6f9	181	7	following	follow	VBG
cord-273487-nfgjz6f9	181	8	sources	source	NNS
cord-273487-nfgjz6f9	181	9	:	:	:
cord-273487-nfgjz6f9	181	10	Complete	complete	VB
cord-273487-nfgjz6f9	181	11	TM	TM	NNP
cord-273487-nfgjz6f9	181	12	EDTA	edta	NN
cord-273487-nfgjz6f9	181	13	-	-	HYPH
cord-273487-nfgjz6f9	181	14	free	free	JJ
cord-273487-nfgjz6f9	181	15	protease	protease	NN
cord-273487-nfgjz6f9	181	16	inhibitor	inhibitor	NN
cord-273487-nfgjz6f9	181	17	cocktail	cocktail	NN
cord-273487-nfgjz6f9	181	18	from	from	IN
cord-273487-nfgjz6f9	181	19	Roche	Roche	NNP
cord-273487-nfgjz6f9	181	20	Diagnostics	Diagnostics	NNP
cord-273487-nfgjz6f9	181	21	(	(	-LRB-
cord-273487-nfgjz6f9	181	22	Laval	Laval	NNP
cord-273487-nfgjz6f9	181	23	,	,	,
cord-273487-nfgjz6f9	181	24	Quebec	Quebec	NNP
cord-273487-nfgjz6f9	181	25	)	)	-RRB-
cord-273487-nfgjz6f9	181	26	;	;	:
cord-273487-nfgjz6f9	181	27	Protein	Protein	NNP
cord-273487-nfgjz6f9	181	28	G	G	NNP
cord-273487-nfgjz6f9	181	29	-	-	HYPH
cord-273487-nfgjz6f9	181	30	sepharose	sepharose	NNP
cord-273487-nfgjz6f9	181	31	from	from	IN
cord-273487-nfgjz6f9	181	32	GE	GE	NNP
cord-273487-nfgjz6f9	181	33	Healthcare	Healthcare	NNP
cord-273487-nfgjz6f9	181	34	Bio	Bio	NNP
cord-273487-nfgjz6f9	181	35	-	-	HYPH
cord-273487-nfgjz6f9	181	36	Sciences	Sciences	NNP
cord-273487-nfgjz6f9	181	37	AB	AB	NNP
cord-273487-nfgjz6f9	181	38	(	(	-LRB-
cord-273487-nfgjz6f9	181	39	Piscataway	Piscataway	NNP
cord-273487-nfgjz6f9	181	40	,	,	,
cord-273487-nfgjz6f9	181	41	NJ	NJ	NNP
cord-273487-nfgjz6f9	181	42	)	)	-RRB-
cord-273487-nfgjz6f9	182	1	;	;	:
cord-273487-nfgjz6f9	182	2	Per	per	IN
cord-273487-nfgjz6f9	182	3	-	-	HYPH
cord-273487-nfgjz6f9	182	4	Fectin	Fectin	NNP
cord-273487-nfgjz6f9	182	5	transfection	transfection	NN
cord-273487-nfgjz6f9	182	6	reagent	reagent	NN
cord-273487-nfgjz6f9	182	7	from	from	IN
cord-273487-nfgjz6f9	182	8	Genlantis	Genlantis	NNP
cord-273487-nfgjz6f9	182	9	(	(	-LRB-
cord-273487-nfgjz6f9	182	10	San	San	NNP
cord-273487-nfgjz6f9	182	11	Diego	Diego	NNP
cord-273487-nfgjz6f9	182	12	,	,	,
cord-273487-nfgjz6f9	182	13	CA	CA	NNP
cord-273487-nfgjz6f9	182	14	)	)	-RRB-
cord-273487-nfgjz6f9	182	15	;	;	:
cord-273487-nfgjz6f9	182	16	TransIT	TransIT	NNP
cord-273487-nfgjz6f9	182	17	s	s	NNP
cord-273487-nfgjz6f9	182	18	-293	-293	NNP
cord-273487-nfgjz6f9	182	19	transfection	transfection	NN
cord-273487-nfgjz6f9	182	20	regent	regent	NN
cord-273487-nfgjz6f9	182	21	from	from	IN
cord-273487-nfgjz6f9	182	22	MirusBio	MirusBio	NNP
cord-273487-nfgjz6f9	182	23	(	(	-LRB-
cord-273487-nfgjz6f9	182	24	Madison	Madison	NNP
cord-273487-nfgjz6f9	182	25	,	,	,
cord-273487-nfgjz6f9	182	26	WI	WI	NNP
cord-273487-nfgjz6f9	182	27	)	)	-RRB-
cord-273487-nfgjz6f9	182	28	;	;	:
cord-273487-nfgjz6f9	182	29	Pierce	Pierce	NNP
cord-273487-nfgjz6f9	182	30	BCA	BCA	NNP
cord-273487-nfgjz6f9	182	31	Protein	Protein	NNP
cord-273487-nfgjz6f9	182	32	Assay	Assay	NNP
cord-273487-nfgjz6f9	182	33	Kit	kit	NN
cord-273487-nfgjz6f9	182	34	from	from	IN
cord-273487-nfgjz6f9	182	35	Thermo	Thermo	NNP
cord-273487-nfgjz6f9	182	36	Scientific	Scientific	NNP
cord-273487-nfgjz6f9	182	37	(	(	-LRB-
cord-273487-nfgjz6f9	182	38	Rockford	Rockford	NNP
cord-273487-nfgjz6f9	182	39	,	,	,
cord-273487-nfgjz6f9	182	40	IL	IL	NNP
cord-273487-nfgjz6f9	182	41	)	)	-RRB-
cord-273487-nfgjz6f9	182	42	;	;	:
cord-273487-nfgjz6f9	182	43	human	human	JJ
cord-273487-nfgjz6f9	182	44	full	full	JJ
cord-273487-nfgjz6f9	182	45	-	-	HYPH
cord-273487-nfgjz6f9	182	46	length	length	NN
cord-273487-nfgjz6f9	182	47	verified	verify	VBN
cord-273487-nfgjz6f9	182	48	DDX56	ddx56	DT
cord-273487-nfgjz6f9	182	49	cDNA	cdna	NN
cord-273487-nfgjz6f9	183	1	(	(	-LRB-
cord-273487-nfgjz6f9	183	2	Clone	clone	NN
cord-273487-nfgjz6f9	183	3	i	-PRON-	PRP
cord-273487-nfgjz6f9	183	4	d	d	NN
cord-273487-nfgjz6f9	183	5	3456547	3456547	CD
cord-273487-nfgjz6f9	183	6	)	)	-RRB-
cord-273487-nfgjz6f9	183	7	and	and	CC
cord-273487-nfgjz6f9	183	8	human	human	JJ
cord-273487-nfgjz6f9	183	9	GIPZ	GIPZ	NNP
cord-273487-nfgjz6f9	183	10	lentiviral	lentiviral	NNP
cord-273487-nfgjz6f9	183	11	shRNAmir	shRNAmir	NNP
cord-273487-nfgjz6f9	183	12	individual	individual	JJ
cord-273487-nfgjz6f9	183	13	clone	clone	NN
cord-273487-nfgjz6f9	184	1	(	(	-LRB-
cord-273487-nfgjz6f9	184	2	Clone	clone	NN
cord-273487-nfgjz6f9	184	3	i	i	PRP
cord-273487-nfgjz6f9	185	1	d	d	LS
cord-273487-nfgjz6f9	185	2	V3LHS_353980	V3LHS_353980	NNP
cord-273487-nfgjz6f9	185	3	)	)	-RRB-
cord-273487-nfgjz6f9	186	1	targeting	target	VBG
cord-273487-nfgjz6f9	186	2	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	186	3	mRNA	mrna	NN
cord-273487-nfgjz6f9	186	4	from	from	IN
cord-273487-nfgjz6f9	186	5	Open	Open	NNP
cord-273487-nfgjz6f9	186	6	Biosystems	Biosystems	NNP
cord-273487-nfgjz6f9	186	7	(	(	-LRB-
cord-273487-nfgjz6f9	186	8	Huntsville	Huntsville	NNP
cord-273487-nfgjz6f9	186	9	,	,	,
cord-273487-nfgjz6f9	186	10	AL	AL	NNP
cord-273487-nfgjz6f9	186	11	)	)	-RRB-
cord-273487-nfgjz6f9	187	1	;	;	:
cord-273487-nfgjz6f9	187	2	HEK	HEK	NNP
cord-273487-nfgjz6f9	187	3	293	293	CD
cord-273487-nfgjz6f9	187	4	T	T	NNP
cord-273487-nfgjz6f9	187	5	,	,	,
cord-273487-nfgjz6f9	187	6	A549	A549	NNP
cord-273487-nfgjz6f9	187	7	and	and	CC
cord-273487-nfgjz6f9	187	8	BHK21	BHK21	NNP
cord-273487-nfgjz6f9	187	9	cells	cell	NNS
cord-273487-nfgjz6f9	187	10	from	from	IN
cord-273487-nfgjz6f9	187	11	the	the	DT
cord-273487-nfgjz6f9	187	12	American	American	NNP
cord-273487-nfgjz6f9	187	13	Type	Type	NNP
cord-273487-nfgjz6f9	187	14	Culture	Culture	NNP
cord-273487-nfgjz6f9	187	15	Collection	Collection	NNP
cord-273487-nfgjz6f9	187	16	(	(	-LRB-
cord-273487-nfgjz6f9	187	17	Manassas	Manassas	NNP
cord-273487-nfgjz6f9	187	18	,	,	,
cord-273487-nfgjz6f9	187	19	VA	VA	NNP
cord-273487-nfgjz6f9	187	20	)	)	-RRB-
cord-273487-nfgjz6f9	188	1	;	;	:
cord-273487-nfgjz6f9	188	2	PerfeCTa	PerfeCTa	NNP
cord-273487-nfgjz6f9	188	3	TM	TM	NNP
cord-273487-nfgjz6f9	188	4	SYBR	SYBR	NNP
cord-273487-nfgjz6f9	188	5	s	s	POS
cord-273487-nfgjz6f9	189	1	Green	Green	NNP
cord-273487-nfgjz6f9	189	2	Supermix	Supermix	NNP
cord-273487-nfgjz6f9	189	3	Low	Low	NNP
cord-273487-nfgjz6f9	189	4	ROX	ROX	NNP
cord-273487-nfgjz6f9	189	5	from	from	IN
cord-273487-nfgjz6f9	189	6	Quanta	Quanta	NNP
cord-273487-nfgjz6f9	189	7	Biosciences	Biosciences	NNP
cord-273487-nfgjz6f9	189	8	(	(	-LRB-
cord-273487-nfgjz6f9	189	9	Gaithersville	Gaithersville	NNP
cord-273487-nfgjz6f9	189	10	,	,	,
cord-273487-nfgjz6f9	189	11	MD	MD	NNP
cord-273487-nfgjz6f9	189	12	)	)	-RRB-
cord-273487-nfgjz6f9	189	13	;	;	:
cord-273487-nfgjz6f9	190	1	SuperScript	SuperScript	NNP
cord-273487-nfgjz6f9	190	2	III	III	NNP
cord-273487-nfgjz6f9	190	3	reverse	reverse	NN
cord-273487-nfgjz6f9	190	4	transcriptase	transcriptase	NN
cord-273487-nfgjz6f9	190	5	cDNA	cdna	NN
cord-273487-nfgjz6f9	190	6	synthesis	synthesis	NN
cord-273487-nfgjz6f9	190	7	kit	kit	NN
cord-273487-nfgjz6f9	190	8	,	,	,
cord-273487-nfgjz6f9	190	9	random	random	JJ
cord-273487-nfgjz6f9	190	10	primers	primer	NNS
cord-273487-nfgjz6f9	190	11	,	,	,
cord-273487-nfgjz6f9	191	1	ProLong	ProLong	NNP
cord-273487-nfgjz6f9	191	2	s	s	NNP
cord-273487-nfgjz6f9	192	1	Gold	Gold	NNP
cord-273487-nfgjz6f9	192	2	Anti	Anti	NNP
cord-273487-nfgjz6f9	192	3	-	-	JJ
cord-273487-nfgjz6f9	192	4	fade	fade	VB
cord-273487-nfgjz6f9	192	5	reagent	reagent	NN
cord-273487-nfgjz6f9	192	6	with	with	IN
cord-273487-nfgjz6f9	192	7	4	4	CD
cord-273487-nfgjz6f9	192	8	0	0	CD
cord-273487-nfgjz6f9	192	9	-6-diamidino-2-phenylindole	-6-diamidino-2-phenylindole	:
cord-273487-nfgjz6f9	192	10	(	(	-LRB-
cord-273487-nfgjz6f9	192	11	DAPI	DAPI	NNP
cord-273487-nfgjz6f9	192	12	)	)	-RRB-
cord-273487-nfgjz6f9	192	13	and	and	CC
cord-273487-nfgjz6f9	192	14	all	all	DT
cord-273487-nfgjz6f9	192	15	other	other	JJ
cord-273487-nfgjz6f9	192	16	reagents	reagent	NNS
cord-273487-nfgjz6f9	192	17	for	for	IN
cord-273487-nfgjz6f9	192	18	mammalian	mammalian	JJ
cord-273487-nfgjz6f9	192	19	cell	cell	NN
cord-273487-nfgjz6f9	192	20	culture	culture	NN
cord-273487-nfgjz6f9	192	21	were	be	VBD
cord-273487-nfgjz6f9	192	22	obtained	obtain	VBN
cord-273487-nfgjz6f9	192	23	from	from	IN
cord-273487-nfgjz6f9	192	24	Invitrogen	Invitrogen	NNP
cord-273487-nfgjz6f9	192	25	(	(	-LRB-
cord-273487-nfgjz6f9	192	26	Carlsbad	Carlsbad	NNP
cord-273487-nfgjz6f9	192	27	,	,	,
cord-273487-nfgjz6f9	192	28	CA	CA	NNP
cord-273487-nfgjz6f9	192	29	)	)	-RRB-
cord-273487-nfgjz6f9	192	30	.	.	.
cord-273487-nfgjz6f9	193	1	Antibodies	antibody	NNS
cord-273487-nfgjz6f9	193	2	were	be	VBD
cord-273487-nfgjz6f9	193	3	obtained	obtain	VBN
cord-273487-nfgjz6f9	193	4	from	from	IN
cord-273487-nfgjz6f9	193	5	the	the	DT
cord-273487-nfgjz6f9	193	6	following	follow	VBG
cord-273487-nfgjz6f9	193	7	sources	source	NNS
cord-273487-nfgjz6f9	193	8	:	:	:
cord-273487-nfgjz6f9	193	9	DDX56specific	DDX56specific	NNP
cord-273487-nfgjz6f9	193	10	mouse	mouse	NN
cord-273487-nfgjz6f9	193	11	monoclonal	monoclonal	JJ
cord-273487-nfgjz6f9	193	12	from	from	IN
cord-273487-nfgjz6f9	193	13	PROGEN	PROGEN	NNP
cord-273487-nfgjz6f9	194	1	Biotechnik	Biotechnik	NNP
cord-273487-nfgjz6f9	194	2	(	(	-LRB-
cord-273487-nfgjz6f9	194	3	Heidelberg	Heidelberg	NNP
cord-273487-nfgjz6f9	194	4	,	,	,
cord-273487-nfgjz6f9	194	5	Germany	Germany	NNP
cord-273487-nfgjz6f9	194	6	)	)	-RRB-
cord-273487-nfgjz6f9	194	7	;	;	:
cord-273487-nfgjz6f9	195	1	rabbit	rabbit	NNP
cord-273487-nfgjz6f9	195	2	and	and	CC
cord-273487-nfgjz6f9	195	3	guinea	guinea	NNP
cord-273487-nfgjz6f9	195	4	pig	pig	NN
cord-273487-nfgjz6f9	195	5	polyclonal	polyclonal	JJ
cord-273487-nfgjz6f9	195	6	antibodies	antibody	NNS
cord-273487-nfgjz6f9	195	7	to	to	IN
cord-273487-nfgjz6f9	195	8	WNV	WNV	NNP
cord-273487-nfgjz6f9	195	9	capsid	capsid	NN
cord-273487-nfgjz6f9	195	10	protein	protein	NN
cord-273487-nfgjz6f9	195	11	were	be	VBD
cord-273487-nfgjz6f9	195	12	generated	generate	VBN
cord-273487-nfgjz6f9	195	13	in	in	IN
cord-273487-nfgjz6f9	195	14	this	this	DT
cord-273487-nfgjz6f9	195	15	laboratory	laboratory	NN
cord-273487-nfgjz6f9	195	16	Xu	Xu	NNP
cord-273487-nfgjz6f9	195	17	et	et	NNP
cord-273487-nfgjz6f9	195	18	al	al	NNP
cord-273487-nfgjz6f9	195	19	.	.	NNP
cord-273487-nfgjz6f9	195	20	,	,	,
cord-273487-nfgjz6f9	195	21	2012	2012	CD
cord-273487-nfgjz6f9	195	22	)	)	-RRB-
cord-273487-nfgjz6f9	195	23	;	;	:
cord-273487-nfgjz6f9	195	24	myc	myc	NN
cord-273487-nfgjz6f9	195	25	-	-	HYPH
cord-273487-nfgjz6f9	195	26	specific	specific	JJ
cord-273487-nfgjz6f9	195	27	mouse	mouse	NN
cord-273487-nfgjz6f9	195	28	monoclonal	monoclonal	JJ
cord-273487-nfgjz6f9	195	29	antibodies	antibody	NNS
cord-273487-nfgjz6f9	195	30	were	be	VBD
cord-273487-nfgjz6f9	195	31	purified	purify	VBN
cord-273487-nfgjz6f9	195	32	from	from	IN
cord-273487-nfgjz6f9	195	33	9E10	9e10	CD
cord-273487-nfgjz6f9	195	34	hybridoma	hybridoma	NN
cord-273487-nfgjz6f9	195	35	cells	cell	NNS
cord-273487-nfgjz6f9	195	36	from	from	IN
cord-273487-nfgjz6f9	195	37	ATCC	ATCC	NNP
cord-273487-nfgjz6f9	195	38	(	(	-LRB-
cord-273487-nfgjz6f9	195	39	Manassas	Manassas	NNP
cord-273487-nfgjz6f9	195	40	,	,	,
cord-273487-nfgjz6f9	195	41	VA	VA	NNP
cord-273487-nfgjz6f9	195	42	)	)	-RRB-
cord-273487-nfgjz6f9	195	43	;	;	:
cord-273487-nfgjz6f9	196	1	b	b	LS
cord-273487-nfgjz6f9	196	2	-	-	HYPH
cord-273487-nfgjz6f9	196	3	actin	actin	NN
cord-273487-nfgjz6f9	196	4	-	-	HYPH
cord-273487-nfgjz6f9	196	5	specific	specific	JJ
cord-273487-nfgjz6f9	196	6	mouse	mouse	NN
cord-273487-nfgjz6f9	196	7	monoclonal	monoclonal	JJ
cord-273487-nfgjz6f9	196	8	antibody	antibody	NN
cord-273487-nfgjz6f9	196	9	,	,	,
cord-273487-nfgjz6f9	196	10	GST	gst	NN
cord-273487-nfgjz6f9	196	11	-	-	HYPH
cord-273487-nfgjz6f9	196	12	specific	specific	JJ
cord-273487-nfgjz6f9	196	13	rabbit	rabbit	NN
cord-273487-nfgjz6f9	196	14	polyclonal	polyclonal	JJ
cord-273487-nfgjz6f9	196	15	antibody	antibody	NN
cord-273487-nfgjz6f9	196	16	and	and	CC
cord-273487-nfgjz6f9	196	17	nucleolin	nucleolin	JJ
cord-273487-nfgjz6f9	196	18	-	-	HYPH
cord-273487-nfgjz6f9	196	19	specific	specific	JJ
cord-273487-nfgjz6f9	196	20	rabbit	rabbit	NN
cord-273487-nfgjz6f9	196	21	antibodies	antibody	NNS
cord-273487-nfgjz6f9	196	22	from	from	IN
cord-273487-nfgjz6f9	196	23	Abcam	Abcam	NNP
cord-273487-nfgjz6f9	196	24	(	(	-LRB-
cord-273487-nfgjz6f9	196	25	Cambridge	Cambridge	NNP
cord-273487-nfgjz6f9	196	26	,	,	,
cord-273487-nfgjz6f9	196	27	MA	MA	NNP
cord-273487-nfgjz6f9	196	28	)	)	-RRB-
cord-273487-nfgjz6f9	196	29	;	;	:
cord-273487-nfgjz6f9	196	30	green	green	JJ
cord-273487-nfgjz6f9	196	31	fluorescent	fluorescent	NN
cord-273487-nfgjz6f9	196	32	protein	protein	NN
cord-273487-nfgjz6f9	196	33	(	(	-LRB-
cord-273487-nfgjz6f9	196	34	GFP)-specific	gfp)-specific	JJ
cord-273487-nfgjz6f9	196	35	rabbit	rabbit	NN
cord-273487-nfgjz6f9	196	36	polyclonal	polyclonal	JJ
cord-273487-nfgjz6f9	196	37	antibody	antibody	NN
cord-273487-nfgjz6f9	196	38	from	from	IN
cord-273487-nfgjz6f9	196	39	Dr.	Dr.	NNP
cord-273487-nfgjz6f9	196	40	L.	L.	NNP
cord-273487-nfgjz6f9	196	41	Berthiaume	Berthiaume	NNP
cord-273487-nfgjz6f9	196	42	(	(	-LRB-
cord-273487-nfgjz6f9	196	43	University	University	NNP
cord-273487-nfgjz6f9	196	44	of	of	IN
cord-273487-nfgjz6f9	196	45	Alberta	Alberta	NNP
cord-273487-nfgjz6f9	196	46	,	,	,
cord-273487-nfgjz6f9	196	47	Edmonton	Edmonton	NNP
cord-273487-nfgjz6f9	196	48	,	,	,
cord-273487-nfgjz6f9	196	49	Canada	Canada	NNP
cord-273487-nfgjz6f9	196	50	)	)	-RRB-
cord-273487-nfgjz6f9	196	51	;	;	:
cord-273487-nfgjz6f9	196	52	goat	goat	NNP
cord-273487-nfgjz6f9	196	53	anti	anti	JJ
cord-273487-nfgjz6f9	196	54	-	-	JJ
cord-273487-nfgjz6f9	196	55	rabbit	rabbit	JJ
cord-273487-nfgjz6f9	196	56	and	and	CC
cord-273487-nfgjz6f9	196	57	goat	goat	NN
cord-273487-nfgjz6f9	196	58	anti	anti	JJ
cord-273487-nfgjz6f9	196	59	-	-	JJ
cord-273487-nfgjz6f9	196	60	mouse	mouse	JJ
cord-273487-nfgjz6f9	196	61	IgG	igg	NN
cord-273487-nfgjz6f9	196	62	conjugated	conjugate	VBN
cord-273487-nfgjz6f9	196	63	to	to	IN
cord-273487-nfgjz6f9	196	64	horseradish	horseradish	NN
cord-273487-nfgjz6f9	196	65	peroxidase	peroxidase	NN
cord-273487-nfgjz6f9	196	66	from	from	IN
cord-273487-nfgjz6f9	196	67	Jackson	Jackson	NNP
cord-273487-nfgjz6f9	196	68	Immuno	Immuno	NNP
cord-273487-nfgjz6f9	196	69	-	-	HYPH
cord-273487-nfgjz6f9	196	70	Research	Research	NNP
cord-273487-nfgjz6f9	196	71	Laboratories	Laboratories	NNP
cord-273487-nfgjz6f9	196	72	(	(	-LRB-
cord-273487-nfgjz6f9	196	73	West	West	NNP
cord-273487-nfgjz6f9	196	74	Grove	Grove	NNP
cord-273487-nfgjz6f9	196	75	,	,	,
cord-273487-nfgjz6f9	196	76	PA	PA	NNP
cord-273487-nfgjz6f9	196	77	)	)	-RRB-
cord-273487-nfgjz6f9	196	78	;	;	:
cord-273487-nfgjz6f9	197	1	donkey	donkey	NNP
cord-273487-nfgjz6f9	197	2	anti	anti	JJ
cord-273487-nfgjz6f9	197	3	-	-	JJ
cord-273487-nfgjz6f9	197	4	mouse	mouse	JJ
cord-273487-nfgjz6f9	197	5	IgG	igg	NN
cord-273487-nfgjz6f9	197	6	conjugated	conjugate	VBN
cord-273487-nfgjz6f9	197	7	to	to	IN
cord-273487-nfgjz6f9	197	8	Alexa	Alexa	NNP
cord-273487-nfgjz6f9	197	9	Fluor	Fluor	NNP
cord-273487-nfgjz6f9	197	10	546	546	CD
cord-273487-nfgjz6f9	197	11	,	,	,
cord-273487-nfgjz6f9	197	12	donkey	donkey	JJ
cord-273487-nfgjz6f9	197	13	anti	anti	JJ
cord-273487-nfgjz6f9	197	14	-	-	JJ
cord-273487-nfgjz6f9	197	15	rabbit	rabbit	JJ
cord-273487-nfgjz6f9	197	16	IgG	igg	NN
cord-273487-nfgjz6f9	197	17	conjugated	conjugate	VBN
cord-273487-nfgjz6f9	197	18	to	to	IN
cord-273487-nfgjz6f9	197	19	Alexa	Alexa	NNP
cord-273487-nfgjz6f9	197	20	Fluor	Fluor	NNP
cord-273487-nfgjz6f9	197	21	647	647	CD
cord-273487-nfgjz6f9	197	22	and	and	CC
cord-273487-nfgjz6f9	197	23	goat	goat	NNP
cord-273487-nfgjz6f9	197	24	anti	anti	JJ
cord-273487-nfgjz6f9	197	25	-	-	JJ
cord-273487-nfgjz6f9	197	26	guinea	guinea	JJ
cord-273487-nfgjz6f9	197	27	pig	pig	NN
cord-273487-nfgjz6f9	197	28	IgG	IgG	NNP
cord-273487-nfgjz6f9	197	29	conjugated	conjugate	VBN
cord-273487-nfgjz6f9	197	30	to	to	IN
cord-273487-nfgjz6f9	197	31	Alexa	Alexa	NNP
cord-273487-nfgjz6f9	197	32	Fluor	Fluor	NNP
cord-273487-nfgjz6f9	197	33	488	488	CD
cord-273487-nfgjz6f9	197	34	from	from	IN
cord-273487-nfgjz6f9	197	35	Invitrogen	Invitrogen	NNP
cord-273487-nfgjz6f9	197	36	(	(	-LRB-
cord-273487-nfgjz6f9	197	37	Carlsbad	Carlsbad	NNP
cord-273487-nfgjz6f9	197	38	,	,	,
cord-273487-nfgjz6f9	197	39	CA	CA	NNP
cord-273487-nfgjz6f9	197	40	)	)	-RRB-
cord-273487-nfgjz6f9	197	41	.	.	.
cord-273487-nfgjz6f9	198	1	All	all	DT
cord-273487-nfgjz6f9	198	2	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	198	3	were	be	VBD
cord-273487-nfgjz6f9	198	4	constructed	construct	VBN
cord-273487-nfgjz6f9	198	5	using	use	VBG
cord-273487-nfgjz6f9	198	6	PCR	PCR	NNP
cord-273487-nfgjz6f9	198	7	and	and	CC
cord-273487-nfgjz6f9	198	8	standard	standard	JJ
cord-273487-nfgjz6f9	198	9	subcloning	subcloning	NN
cord-273487-nfgjz6f9	198	10	techniques	technique	NNS
cord-273487-nfgjz6f9	198	11	.	.	.
cord-273487-nfgjz6f9	199	1	Prior	prior	RB
cord-273487-nfgjz6f9	199	2	to	to	TO
cord-273487-nfgjz6f9	199	3	use	use	VB
cord-273487-nfgjz6f9	199	4	in	in	IN
cord-273487-nfgjz6f9	199	5	experiments	experiment	NNS
cord-273487-nfgjz6f9	199	6	,	,	,
cord-273487-nfgjz6f9	199	7	the	the	DT
cord-273487-nfgjz6f9	199	8	newly	newly	RB
cord-273487-nfgjz6f9	199	9	constructed	construct	VBN
cord-273487-nfgjz6f9	199	10	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	199	11	were	be	VBD
cord-273487-nfgjz6f9	199	12	verified	verify	VBN
cord-273487-nfgjz6f9	199	13	by	by	IN
cord-273487-nfgjz6f9	199	14	diagnostic	diagnostic	JJ
cord-273487-nfgjz6f9	199	15	restriction	restriction	NN
cord-273487-nfgjz6f9	199	16	endonuclease	endonuclease	NN
cord-273487-nfgjz6f9	199	17	digestion	digestion	NN
cord-273487-nfgjz6f9	199	18	and	and	CC
cord-273487-nfgjz6f9	199	19	DNA	dna	NN
cord-273487-nfgjz6f9	199	20	sequencing	sequencing	NN
cord-273487-nfgjz6f9	199	21	.	.	.
cord-273487-nfgjz6f9	200	1	Constructs	construct	NNS
cord-273487-nfgjz6f9	200	2	encoding	encode	VBG
cord-273487-nfgjz6f9	200	3	myc	myc	NNP
cord-273487-nfgjz6f9	200	4	-	-	HYPH
cord-273487-nfgjz6f9	200	5	tagged	tag	VBN
cord-273487-nfgjz6f9	200	6	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	200	7	resistant	resistant	JJ
cord-273487-nfgjz6f9	200	8	forms	form	NNS
cord-273487-nfgjz6f9	200	9	of	of	IN
cord-273487-nfgjz6f9	200	10	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	200	11	were	be	VBD
cord-273487-nfgjz6f9	200	12	generated	generate	VBN
cord-273487-nfgjz6f9	200	13	using	use	VBG
cord-273487-nfgjz6f9	200	14	the	the	DT
cord-273487-nfgjz6f9	200	15	overlap	overlap	NN
cord-273487-nfgjz6f9	200	16	extension	extension	NN
cord-273487-nfgjz6f9	200	17	PCR	pcr	NN
cord-273487-nfgjz6f9	200	18	method	method	NN
cord-273487-nfgjz6f9	200	19	.	.	.
cord-273487-nfgjz6f9	201	1	For	for	IN
cord-273487-nfgjz6f9	201	2	the	the	DT
cord-273487-nfgjz6f9	201	3	first	first	JJ
cord-273487-nfgjz6f9	201	4	PCR	PCR	NNP
cord-273487-nfgjz6f9	201	5	,	,	,
cord-273487-nfgjz6f9	201	6	the	the	DT
cord-273487-nfgjz6f9	201	7	plasmid	plasmid	NN
cord-273487-nfgjz6f9	201	8	pcDNA3.1(-)-DDX56-myc	pcDNA3.1(-)-DDX56-myc	NNP
cord-273487-nfgjz6f9	201	9	(	(	-LRB-
cord-273487-nfgjz6f9	201	10	Xu	Xu	NNP
cord-273487-nfgjz6f9	201	11	,	,	,
cord-273487-nfgjz6f9	201	12	Anderson	Anderson	NNP
cord-273487-nfgjz6f9	201	13	,	,	,
cord-273487-nfgjz6f9	201	14	and	and	CC
cord-273487-nfgjz6f9	201	15	Hobman	Hobman	NNP
cord-273487-nfgjz6f9	201	16	,	,	,
cord-273487-nfgjz6f9	201	17	2011	2011	CD
cord-273487-nfgjz6f9	201	18	)	)	-RRB-
cord-273487-nfgjz6f9	201	19	served	serve	VBD
cord-273487-nfgjz6f9	201	20	as	as	IN
cord-273487-nfgjz6f9	201	21	the	the	DT
cord-273487-nfgjz6f9	201	22	template	template	NN
cord-273487-nfgjz6f9	201	23	.	.	.
cord-273487-nfgjz6f9	202	1	Primer	primer	NN
cord-273487-nfgjz6f9	202	2	pairs	pair	NNS
cord-273487-nfgjz6f9	202	3	used	use	VBN
cord-273487-nfgjz6f9	202	4	for	for	IN
cord-273487-nfgjz6f9	202	5	the	the	DT
cord-273487-nfgjz6f9	202	6	first	first	JJ
cord-273487-nfgjz6f9	202	7	PCR	PCR	NNP
cord-273487-nfgjz6f9	202	8	were	be	VBD
cord-273487-nfgjz6f9	202	9	NotI	NotI	NNP
cord-273487-nfgjz6f9	202	10	-	-	HYPH
cord-273487-nfgjz6f9	202	11	F	F	NNP
cord-273487-nfgjz6f9	202	12	and	and	CC
cord-273487-nfgjz6f9	202	13	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	202	14	-	-	HYPH
cord-273487-nfgjz6f9	202	15	resistant	resistant	JJ
cord-273487-nfgjz6f9	202	16	-	-	HYPH
cord-273487-nfgjz6f9	202	17	R	r	NN
cord-273487-nfgjz6f9	202	18	and	and	CC
cord-273487-nfgjz6f9	202	19	MluI	MluI	NNP
cord-273487-nfgjz6f9	202	20	-	-	HYPH
cord-273487-nfgjz6f9	202	21	R	R	NNP
cord-273487-nfgjz6f9	202	22	and	and	CC
cord-273487-nfgjz6f9	202	23	RNAi	rnai	NN
cord-273487-nfgjz6f9	202	24	-	-	HYPH
cord-273487-nfgjz6f9	202	25	resistant	resistant	JJ
cord-273487-nfgjz6f9	202	26	-	-	HYPH
cord-273487-nfgjz6f9	202	27	F	f	NN
cord-273487-nfgjz6f9	202	28	(	(	-LRB-
cord-273487-nfgjz6f9	202	29	Table	Table	NNP
cord-273487-nfgjz6f9	202	30	1	1	CD
cord-273487-nfgjz6f9	202	31	)	)	-RRB-
cord-273487-nfgjz6f9	202	32	.	.	.
cord-273487-nfgjz6f9	203	1	The	the	DT
cord-273487-nfgjz6f9	203	2	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	203	3	-	-	HYPH
cord-273487-nfgjz6f9	203	4	resistant	resistant	JJ
cord-273487-nfgjz6f9	203	5	mutations	mutation	NNS
cord-273487-nfgjz6f9	203	6	were	be	VBD
cord-273487-nfgjz6f9	203	7	designed	design	VBN
cord-273487-nfgjz6f9	203	8	based	base	VBN
cord-273487-nfgjz6f9	203	9	on	on	IN
cord-273487-nfgjz6f9	203	10	the	the	DT
cord-273487-nfgjz6f9	203	11	target	target	NN
cord-273487-nfgjz6f9	203	12	sequence	sequence	NN
cord-273487-nfgjz6f9	203	13	recognized	recognize	VBN
cord-273487-nfgjz6f9	203	14	by	by	IN
cord-273487-nfgjz6f9	203	15	the	the	DT
cord-273487-nfgjz6f9	203	16	DDX56specific	DDX56specific	NNP
cord-273487-nfgjz6f9	203	17	shRNAmir-353980	shRNAmir-353980	NNP
cord-273487-nfgjz6f9	203	18	targeting	targeting	NN
cord-273487-nfgjz6f9	203	19	sequence	sequence	NN
cord-273487-nfgjz6f9	203	20	as	as	IN
cord-273487-nfgjz6f9	203	21	shown	show	VBN
cord-273487-nfgjz6f9	203	22	in	in	IN
cord-273487-nfgjz6f9	203	23	Fig	Fig	NNP
cord-273487-nfgjz6f9	203	24	.	.	.
cord-273487-nfgjz6f9	204	1	1	1	LS
cord-273487-nfgjz6f9	204	2	.	.	.
cord-273487-nfgjz6f9	205	1	The	the	DT
cord-273487-nfgjz6f9	205	2	product	product	NN
cord-273487-nfgjz6f9	205	3	of	of	IN
cord-273487-nfgjz6f9	205	4	the	the	DT
cord-273487-nfgjz6f9	205	5	overlap	overlap	NN
cord-273487-nfgjz6f9	205	6	PCR	PCR	NNP
cord-273487-nfgjz6f9	205	7	which	which	WDT
cord-273487-nfgjz6f9	205	8	was	be	VBD
cord-273487-nfgjz6f9	205	9	amplified	amplify	VBN
cord-273487-nfgjz6f9	205	10	using	use	VBG
cord-273487-nfgjz6f9	205	11	primers	primer	NNS
cord-273487-nfgjz6f9	205	12	NotI	NotI	NNP
cord-273487-nfgjz6f9	205	13	-	-	HYPH
cord-273487-nfgjz6f9	205	14	F	F	NNP
cord-273487-nfgjz6f9	205	15	and	and	CC
cord-273487-nfgjz6f9	205	16	MluI	MluI	NNP
cord-273487-nfgjz6f9	205	17	-	-	HYPH
cord-273487-nfgjz6f9	205	18	R	R	NNP
cord-273487-nfgjz6f9	205	19	was	be	VBD
cord-273487-nfgjz6f9	205	20	subcloned	subclone	VBN
cord-273487-nfgjz6f9	205	21	into	into	IN
cord-273487-nfgjz6f9	205	22	the	the	DT
cord-273487-nfgjz6f9	205	23	Not	not	RB
cord-273487-nfgjz6f9	205	24	I	-PRON-	PRP
cord-273487-nfgjz6f9	205	25	and	and	CC
cord-273487-nfgjz6f9	206	1	Mlu	Mlu	NNP
cord-273487-nfgjz6f9	206	2	I	-PRON-	PRP
cord-273487-nfgjz6f9	206	3	sites	site	NNS
cord-273487-nfgjz6f9	206	4	of	of	IN
cord-273487-nfgjz6f9	206	5	pLVX	plvx	JJ
cord-273487-nfgjz6f9	206	6	-	-	HYPH
cord-273487-nfgjz6f9	206	7	Tight	Tight	NNP
cord-273487-nfgjz6f9	206	8	-	-	HYPH
cord-273487-nfgjz6f9	206	9	Puro	Puro	NNP
cord-273487-nfgjz6f9	206	10	to	to	TO
cord-273487-nfgjz6f9	206	11	produce	produce	VB
cord-273487-nfgjz6f9	207	1	pLVX	plvx	LS
cord-273487-nfgjz6f9	207	2	-	-	JJ
cord-273487-nfgjz6f9	207	3	DDX56-wt	ddx56-wt	JJ
cord-273487-nfgjz6f9	207	4	-	-	HYPH
cord-273487-nfgjz6f9	207	5	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	207	6	-	-	HYPH
cord-273487-nfgjz6f9	207	7	R.	R.	NNP
cord-273487-nfgjz6f9	207	8	To	to	TO
cord-273487-nfgjz6f9	207	9	generate	generate	VB
cord-273487-nfgjz6f9	207	10	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	207	11	-	-	HYPH
cord-273487-nfgjz6f9	207	12	resistant	resistant	JJ
cord-273487-nfgjz6f9	207	13	DEAD	dead	JJ
cord-273487-nfgjz6f9	207	14	box	box	NN
cord-273487-nfgjz6f9	207	15	mutants	mutant	NNS
cord-273487-nfgjz6f9	207	16	of	of	IN
cord-273487-nfgjz6f9	207	17	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	207	18	,	,	,
cord-273487-nfgjz6f9	207	19	the	the	DT
cord-273487-nfgjz6f9	207	20	wild	wild	JJ
cord-273487-nfgjz6f9	207	21	type	type	NN
cord-273487-nfgjz6f9	207	22	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	207	23	resistant	resistant	JJ
cord-273487-nfgjz6f9	207	24	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	207	25	cDNA	cdna	NN
cord-273487-nfgjz6f9	207	26	produced	produce	VBN
cord-273487-nfgjz6f9	207	27	as	as	IN
cord-273487-nfgjz6f9	207	28	described	describe	VBN
cord-273487-nfgjz6f9	207	29	above	above	RB
cord-273487-nfgjz6f9	207	30	was	be	VBD
cord-273487-nfgjz6f9	207	31	subjected	subject	VBN
cord-273487-nfgjz6f9	207	32	to	to	IN
cord-273487-nfgjz6f9	207	33	PCR	PCR	NNP
cord-273487-nfgjz6f9	207	34	using	use	VBG
cord-273487-nfgjz6f9	207	35	the	the	DT
cord-273487-nfgjz6f9	207	36	primer	primer	NN
cord-273487-nfgjz6f9	207	37	pair	pair	NN
cord-273487-nfgjz6f9	207	38	NotI	NotI	NNP
cord-273487-nfgjz6f9	207	39	-	-	HYPH
cord-273487-nfgjz6f9	207	40	F	F	NNP
cord-273487-nfgjz6f9	207	41	/	/	SYM
cord-273487-nfgjz6f9	207	42	MluI	MluI	NNP
cord-273487-nfgjz6f9	207	43	-	-	HYPH
cord-273487-nfgjz6f9	207	44	R	R	NNP
cord-273487-nfgjz6f9	207	45	together	together	RB
cord-273487-nfgjz6f9	207	46	with	with	IN
cord-273487-nfgjz6f9	207	47	primers	primer	NNS
cord-273487-nfgjz6f9	207	48	that	that	WDT
cord-273487-nfgjz6f9	207	49	introduce	introduce	VBP
cord-273487-nfgjz6f9	207	50	mutations	mutation	NNS
cord-273487-nfgjz6f9	207	51	into	into	IN
cord-273487-nfgjz6f9	207	52	the	the	DT
cord-273487-nfgjz6f9	207	53	DEAD	dead	JJ
cord-273487-nfgjz6f9	207	54	box	box	NN
cord-273487-nfgjz6f9	207	55	motif	motif	NN
cord-273487-nfgjz6f9	207	56	(	(	-LRB-
cord-273487-nfgjz6f9	207	57	D166N	D166N	NNP
cord-273487-nfgjz6f9	207	58	-	-	HYPH
cord-273487-nfgjz6f9	207	59	F	F	NNP
cord-273487-nfgjz6f9	207	60	and	and	CC
cord-273487-nfgjz6f9	207	61	D166N	D166N	NNP
cord-273487-nfgjz6f9	207	62	-	-	HYPH
cord-273487-nfgjz6f9	207	63	R	R	NNP
cord-273487-nfgjz6f9	207	64	;	;	,
cord-273487-nfgjz6f9	207	65	E167Q	e167q	NN
cord-273487-nfgjz6f9	207	66	-	-	HYPH
cord-273487-nfgjz6f9	207	67	F	f	NN
cord-273487-nfgjz6f9	207	68	and	and	CC
cord-273487-nfgjz6f9	207	69	E167Q	E167Q	NNP
cord-273487-nfgjz6f9	207	70	-	-	HYPH
cord-273487-nfgjz6f9	207	71	R	r	NN
cord-273487-nfgjz6f9	207	72	)	)	-RRB-
cord-273487-nfgjz6f9	207	73	.	.	.
cord-273487-nfgjz6f9	208	1	The	the	DT
cord-273487-nfgjz6f9	208	2	resulting	result	VBG
cord-273487-nfgjz6f9	208	3	cDNAs	cDNAs	.
cord-273487-nfgjz6f9	209	1	(	(	-LRB-
cord-273487-nfgjz6f9	209	2	D166N	D166N	NNP
cord-273487-nfgjz6f9	209	3	and	and	CC
cord-273487-nfgjz6f9	209	4	E167Q	E167Q	NNP
cord-273487-nfgjz6f9	209	5	)	)	-RRB-
cord-273487-nfgjz6f9	209	6	were	be	VBD
cord-273487-nfgjz6f9	209	7	then	then	RB
cord-273487-nfgjz6f9	209	8	subcloned	subclone	VBN
cord-273487-nfgjz6f9	209	9	into	into	IN
cord-273487-nfgjz6f9	209	10	the	the	DT
cord-273487-nfgjz6f9	209	11	Not	not	RB
cord-273487-nfgjz6f9	209	12	I	-PRON-	PRP
cord-273487-nfgjz6f9	209	13	and	and	CC
cord-273487-nfgjz6f9	210	1	Mlu	Mlu	NNP
cord-273487-nfgjz6f9	210	2	I	-PRON-	PRP
cord-273487-nfgjz6f9	210	3	sites	site	NNS
cord-273487-nfgjz6f9	210	4	of	of	IN
cord-273487-nfgjz6f9	210	5	pLVX	plvx	JJ
cord-273487-nfgjz6f9	210	6	-	-	HYPH
cord-273487-nfgjz6f9	210	7	Tight	Tight	NNP
cord-273487-nfgjz6f9	210	8	-	-	HYPH
cord-273487-nfgjz6f9	210	9	Puro	Puro	NNP
cord-273487-nfgjz6f9	210	10	to	to	TO
cord-273487-nfgjz6f9	210	11	produce	produce	VB
cord-273487-nfgjz6f9	210	12	pLVX	pLVX	VBN
cord-273487-nfgjz6f9	210	13	-	-	JJ
cord-273487-nfgjz6f9	210	14	DDX56-D166N	DDX56-D166N	NNP
cord-273487-nfgjz6f9	210	15	-	-	HYPH
cord-273487-nfgjz6f9	210	16	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	210	17	-	-	HYPH
cord-273487-nfgjz6f9	210	18	R	R	NNP
cord-273487-nfgjz6f9	210	19	and	and	CC
cord-273487-nfgjz6f9	210	20	pLVX	plvx	JJ
cord-273487-nfgjz6f9	210	21	-	-	JJ
cord-273487-nfgjz6f9	210	22	DDX56-E167Q	DDX56-E167Q	NNP
cord-273487-nfgjz6f9	210	23	-	-	HYPH
cord-273487-nfgjz6f9	210	24	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	210	25	-	-	HYPH
cord-273487-nfgjz6f9	210	26	R	R	NNP
cord-273487-nfgjz6f9	210	27	,	,	,
cord-273487-nfgjz6f9	210	28	respectively	respectively	RB
cord-273487-nfgjz6f9	210	29	.	.	.
cord-273487-nfgjz6f9	211	1	The	the	DT
cord-273487-nfgjz6f9	211	2	cDNAs	cdna	NNS
cord-273487-nfgjz6f9	211	3	encoding	encode	VBG
cord-273487-nfgjz6f9	211	4	RNAi	rnai	NN
cord-273487-nfgjz6f9	211	5	-	-	HYPH
cord-273487-nfgjz6f9	211	6	resistant	resistant	JJ
cord-273487-nfgjz6f9	211	7	wild	wild	JJ
cord-273487-nfgjz6f9	211	8	type	type	NN
cord-273487-nfgjz6f9	211	9	,	,	,
cord-273487-nfgjz6f9	211	10	D166N	d166n	NN
cord-273487-nfgjz6f9	211	11	and	and	CC
cord-273487-nfgjz6f9	211	12	E167Q	E167Q	MD
cord-273487-nfgjz6f9	211	13	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	211	14	were	be	VBD
cord-273487-nfgjz6f9	211	15	excised	excise	VBN
cord-273487-nfgjz6f9	211	16	from	from	IN
cord-273487-nfgjz6f9	211	17	the	the	DT
cord-273487-nfgjz6f9	211	18	pLVX	pLVX	NNP
cord-273487-nfgjz6f9	211	19	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	211	20	and	and	CC
cord-273487-nfgjz6f9	211	21	subcloned	subclone	VBN
cord-273487-nfgjz6f9	211	22	into	into	IN
cord-273487-nfgjz6f9	211	23	the	the	DT
cord-273487-nfgjz6f9	211	24	Spe	Spe	NNP
cord-273487-nfgjz6f9	211	25	I	i	NN
cord-273487-nfgjz6f9	211	26	and	and	CC
cord-273487-nfgjz6f9	211	27	Xho	Xho	NNP
cord-273487-nfgjz6f9	212	1	I	-PRON-	PRP
cord-273487-nfgjz6f9	212	2	sites	site	NNS
cord-273487-nfgjz6f9	212	3	of	of	IN
cord-273487-nfgjz6f9	212	4	the	the	DT
cord-273487-nfgjz6f9	212	5	lentiviral	lentiviral	JJ
cord-273487-nfgjz6f9	212	6	vector	vector	NN
cord-273487-nfgjz6f9	212	7	pTRIP	pTRIP	NNP
cord-273487-nfgjz6f9	212	8	-	-	HYPH
cord-273487-nfgjz6f9	212	9	CMV	CMV	NNP
cord-273487-nfgjz6f9	212	10	-	-	HYPH
cord-273487-nfgjz6f9	212	11	MCS	MCS	NNP
cord-273487-nfgjz6f9	212	12	-	-	HYPH
cord-273487-nfgjz6f9	212	13	IRES	IRES	NNP
cord-273487-nfgjz6f9	212	14	-	-	HYPH
cord-273487-nfgjz6f9	212	15	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	212	16	.	.	.
cord-273487-nfgjz6f9	213	1	The	the	DT
cord-273487-nfgjz6f9	213	2	resulting	result	VBG
cord-273487-nfgjz6f9	213	3	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	214	1	pTRIP	ptrip	JJ
cord-273487-nfgjz6f9	214	2	-	-	HYPH
cord-273487-nfgjz6f9	214	3	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	214	4	-	-	HYPH
cord-273487-nfgjz6f9	214	5	DDX56-wt	DDX56-wt	NNP
cord-273487-nfgjz6f9	214	6	,	,	,
cord-273487-nfgjz6f9	214	7	D166N	D166N	NNP
cord-273487-nfgjz6f9	214	8	,	,	,
cord-273487-nfgjz6f9	214	9	and	and	CC
cord-273487-nfgjz6f9	214	10	E167Q	E167Q	NNP
cord-273487-nfgjz6f9	214	11	-	-	HYPH
cord-273487-nfgjz6f9	214	12	RNAi	RNAi	NNS
cord-273487-nfgjz6f9	214	13	-	-	HYPH
cord-273487-nfgjz6f9	214	14	R	R	NNP
cord-273487-nfgjz6f9	214	15	,	,	,
cord-273487-nfgjz6f9	214	16	respectively	respectively	RB
cord-273487-nfgjz6f9	214	17	,	,	,
cord-273487-nfgjz6f9	214	18	direct	direct	JJ
cord-273487-nfgjz6f9	214	19	independent	independent	JJ
cord-273487-nfgjz6f9	214	20	expression	expression	NN
cord-273487-nfgjz6f9	214	21	of	of	IN
cord-273487-nfgjz6f9	214	22	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	214	23	and	and	CC
cord-273487-nfgjz6f9	214	24	DDX56	ddx56	DT
cord-273487-nfgjz6f9	214	25	wild	wild	JJ
cord-273487-nfgjz6f9	214	26	type	type	NN
cord-273487-nfgjz6f9	214	27	and	and	CC
cord-273487-nfgjz6f9	214	28	mutants	mutant	NNS
cord-273487-nfgjz6f9	214	29	.	.	.
cord-273487-nfgjz6f9	215	1	The	the	DT
cord-273487-nfgjz6f9	215	2	plasmid	plasmid	JJ
cord-273487-nfgjz6f9	215	3	pTRIP	ptrip	JJ
cord-273487-nfgjz6f9	215	4	-	-	HYPH
cord-273487-nfgjz6f9	215	5	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	215	6	-	-	HYPH
cord-273487-nfgjz6f9	215	7	DDX56-wt	DDX56-wt	NNP
cord-273487-nfgjz6f9	215	8	-	-	HYPH
cord-273487-nfgjz6f9	215	9	RNAi	RNAi	NNP
cord-273487-nfgjz6f9	215	10	-	-	HYPH
cord-273487-nfgjz6f9	215	11	S	S	NNP
cord-273487-nfgjz6f9	215	12	(	(	-LRB-
cord-273487-nfgjz6f9	215	13	sensitive	sensitive	JJ
cord-273487-nfgjz6f9	215	14	)	)	-RRB-
cord-273487-nfgjz6f9	215	15	was	be	VBD
cord-273487-nfgjz6f9	215	16	created	create	VBN
cord-273487-nfgjz6f9	215	17	by	by	IN
cord-273487-nfgjz6f9	215	18	ligation	ligation	NN
cord-273487-nfgjz6f9	215	19	of	of	IN
cord-273487-nfgjz6f9	215	20	a	a	DT
cord-273487-nfgjz6f9	215	21	cDNA	cdna	NN
cord-273487-nfgjz6f9	215	22	encoding	encode	VBG
cord-273487-nfgjz6f9	215	23	wild	wild	JJ
cord-273487-nfgjz6f9	215	24	type	type	NN
cord-273487-nfgjz6f9	215	25	myc	myc	NNP
cord-273487-nfgjz6f9	215	26	-	-	HYPH
cord-273487-nfgjz6f9	215	27	tagged	tag	VBN
cord-273487-nfgjz6f9	215	28	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	215	29	into	into	IN
cord-273487-nfgjz6f9	215	30	the	the	DT
cord-273487-nfgjz6f9	215	31	Spe	Spe	NNP
cord-273487-nfgjz6f9	215	32	I	i	NN
cord-273487-nfgjz6f9	215	33	and	and	CC
cord-273487-nfgjz6f9	215	34	Xho	Xho	NNP
cord-273487-nfgjz6f9	216	1	I	-PRON-	PRP
cord-273487-nfgjz6f9	216	2	sites	site	NNS
cord-273487-nfgjz6f9	216	3	of	of	IN
cord-273487-nfgjz6f9	216	4	pTRIP	ptrip	JJ
cord-273487-nfgjz6f9	216	5	-	-	HYPH
cord-273487-nfgjz6f9	216	6	IRES	IRES	NNP
cord-273487-nfgjz6f9	216	7	-	-	HYPH
cord-273487-nfgjz6f9	216	8	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	216	9	.	.	.
cord-273487-nfgjz6f9	217	1	DNA	dna	NN
cord-273487-nfgjz6f9	217	2	fragments	fragment	NNS
cord-273487-nfgjz6f9	217	3	encoding	encode	VBG
cord-273487-nfgjz6f9	217	4	myc	myc	NNP
cord-273487-nfgjz6f9	217	5	-	-	HYPH
cord-273487-nfgjz6f9	217	6	tagged	tag	VBN
cord-273487-nfgjz6f9	217	7	amino	amino	NN
cord-273487-nfgjz6f9	217	8	acid	acid	NN
cord-273487-nfgjz6f9	217	9	residues	residue	NNS
cord-273487-nfgjz6f9	217	10	1	1	CD
cord-273487-nfgjz6f9	217	11	-	-	SYM
cord-273487-nfgjz6f9	217	12	218	218	CD
cord-273487-nfgjz6f9	217	13	and	and	CC
cord-273487-nfgjz6f9	217	14	219	219	CD
cord-273487-nfgjz6f9	217	15	-	-	SYM
cord-273487-nfgjz6f9	217	16	547	547	CD
cord-273487-nfgjz6f9	217	17	of	of	IN
cord-273487-nfgjz6f9	217	18	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	217	19	were	be	VBD
cord-273487-nfgjz6f9	217	20	generated	generate	VBN
cord-273487-nfgjz6f9	217	21	by	by	IN
cord-273487-nfgjz6f9	217	22	PCR	PCR	NNP
cord-273487-nfgjz6f9	217	23	with	with	IN
cord-273487-nfgjz6f9	217	24	primers	primer	NNS
cord-273487-nfgjz6f9	217	25	pairs	pair	NNS
cord-273487-nfgjz6f9	217	26	DDX56-F	ddx56-f	NN
cord-273487-nfgjz6f9	217	27	/	/	SYM
cord-273487-nfgjz6f9	217	28	DDX56-NT	DDX56-NT	NNP
cord-273487-nfgjz6f9	217	29	-	-	HYPH
cord-273487-nfgjz6f9	217	30	R	R	NNP
cord-273487-nfgjz6f9	217	31	and	and	CC
cord-273487-nfgjz6f9	217	32	DDX56-CT	DDX56-CT	NNP
cord-273487-nfgjz6f9	217	33	-	-	HYPH
cord-273487-nfgjz6f9	217	34	F	F	NNP
cord-273487-nfgjz6f9	217	35	/	/	SYM
cord-273487-nfgjz6f9	217	36	DDX56-R	ddx56-r	NN
cord-273487-nfgjz6f9	217	37	,	,	,
cord-273487-nfgjz6f9	217	38	respectively	respectively	RB
cord-273487-nfgjz6f9	217	39	,	,	,
cord-273487-nfgjz6f9	217	40	using	use	VBG
cord-273487-nfgjz6f9	217	41	the	the	DT
cord-273487-nfgjz6f9	217	42	plasmid	plasmid	NN
cord-273487-nfgjz6f9	217	43	pcDNA3.1(-)-DDX56-myc	pcDNA3.1(-)-DDX56-myc	NNP
cord-273487-nfgjz6f9	217	44	(	(	-LRB-
cord-273487-nfgjz6f9	217	45	Xu	Xu	NNP
cord-273487-nfgjz6f9	217	46	,	,	,
cord-273487-nfgjz6f9	217	47	Anderson	Anderson	NNP
cord-273487-nfgjz6f9	217	48	,	,	,
cord-273487-nfgjz6f9	217	49	and	and	CC
cord-273487-nfgjz6f9	217	50	Hobman	Hobman	NNP
cord-273487-nfgjz6f9	217	51	,	,	,
cord-273487-nfgjz6f9	217	52	2011	2011	CD
cord-273487-nfgjz6f9	217	53	)	)	-RRB-
cord-273487-nfgjz6f9	217	54	as	as	IN
cord-273487-nfgjz6f9	217	55	template	template	NN
cord-273487-nfgjz6f9	217	56	.	.	.
cord-273487-nfgjz6f9	218	1	The	the	DT
cord-273487-nfgjz6f9	218	2	resulting	result	VBG
cord-273487-nfgjz6f9	218	3	cDNAs	cdna	NNS
cord-273487-nfgjz6f9	218	4	were	be	VBD
cord-273487-nfgjz6f9	218	5	ligated	ligate	VBN
cord-273487-nfgjz6f9	218	6	into	into	IN
cord-273487-nfgjz6f9	218	7	the	the	DT
cord-273487-nfgjz6f9	218	8	EcoR	EcoR	NNP
cord-273487-nfgjz6f9	218	9	I	-PRON-	PRP
cord-273487-nfgjz6f9	218	10	and	and	CC
cord-273487-nfgjz6f9	218	11	BamH	BamH	NNP
cord-273487-nfgjz6f9	218	12	I	-PRON-	PRP
cord-273487-nfgjz6f9	218	13	sites	site	NNS
cord-273487-nfgjz6f9	218	14	of	of	IN
cord-273487-nfgjz6f9	218	15	the	the	DT
cord-273487-nfgjz6f9	218	16	mammalian	mammalian	JJ
cord-273487-nfgjz6f9	218	17	expression	expression	NN
cord-273487-nfgjz6f9	218	18	vector	vector	NN
cord-273487-nfgjz6f9	218	19	pcDNA3.1(-)-myc	pcDNA3.1(-)-myc	NNP
cord-273487-nfgjz6f9	218	20	.	.	.
cord-273487-nfgjz6f9	219	1	Myc	Myc	NNP
cord-273487-nfgjz6f9	219	2	-	-	HYPH
cord-273487-nfgjz6f9	219	3	tagged	tag	VBN
cord-273487-nfgjz6f9	219	4	DDX56-NT	DDX56-NT	NNP
cord-273487-nfgjz6f9	219	5	and	and	CC
cord-273487-nfgjz6f9	219	6	DDX56-CT	DDX56-CT	NNP
cord-273487-nfgjz6f9	219	7	cDNAs	cdna	NNS
cord-273487-nfgjz6f9	219	8	produced	produce	VBN
cord-273487-nfgjz6f9	219	9	by	by	IN
cord-273487-nfgjz6f9	219	10	PCR	PCR	NNP
cord-273487-nfgjz6f9	220	1	using	use	VBG
cord-273487-nfgjz6f9	220	2	primers	primer	NNS
cord-273487-nfgjz6f9	220	3	SpeI	SpeI	NNP
cord-273487-nfgjz6f9	220	4	-	-	HYPH
cord-273487-nfgjz6f9	220	5	EcoRV	EcoRV	NNP
cord-273487-nfgjz6f9	220	6	-	-	HYPH
cord-273487-nfgjz6f9	220	7	F	F	NNP
cord-273487-nfgjz6f9	220	8	and	and	CC
cord-273487-nfgjz6f9	220	9	XhoI	XhoI	NNP
cord-273487-nfgjz6f9	220	10	-	-	HYPH
cord-273487-nfgjz6f9	220	11	R	R	NNP
cord-273487-nfgjz6f9	220	12	were	be	VBD
cord-273487-nfgjz6f9	220	13	also	also	RB
cord-273487-nfgjz6f9	220	14	ligated	ligate	VBN
cord-273487-nfgjz6f9	220	15	into	into	IN
cord-273487-nfgjz6f9	220	16	the	the	DT
cord-273487-nfgjz6f9	220	17	Spe	Spe	NNP
cord-273487-nfgjz6f9	220	18	I	i	NN
cord-273487-nfgjz6f9	220	19	and	and	CC
cord-273487-nfgjz6f9	220	20	Xho	Xho	NNP
cord-273487-nfgjz6f9	221	1	I	-PRON-	PRP
cord-273487-nfgjz6f9	221	2	sites	site	NNS
cord-273487-nfgjz6f9	221	3	of	of	IN
cord-273487-nfgjz6f9	221	4	the	the	DT
cord-273487-nfgjz6f9	221	5	lentiviral	lentiviral	JJ
cord-273487-nfgjz6f9	221	6	vector	vector	NN
cord-273487-nfgjz6f9	221	7	pTRIP	pTRIP	NNP
cord-273487-nfgjz6f9	221	8	-	-	HYPH
cord-273487-nfgjz6f9	221	9	CMV	CMV	NNP
cord-273487-nfgjz6f9	221	10	-	-	HYPH
cord-273487-nfgjz6f9	221	11	MCS	MCS	NNP
cord-273487-nfgjz6f9	221	12	-	-	HYPH
cord-273487-nfgjz6f9	221	13	IRES	IRES	NNP
cord-273487-nfgjz6f9	221	14	-	-	HYPH
cord-273487-nfgjz6f9	221	15	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	221	16	.	.	.
cord-273487-nfgjz6f9	222	1	Construction	construction	NN
cord-273487-nfgjz6f9	222	2	of	of	IN
cord-273487-nfgjz6f9	222	3	the	the	DT
cord-273487-nfgjz6f9	222	4	mammalian	mammalian	JJ
cord-273487-nfgjz6f9	222	5	expression	expression	NN
cord-273487-nfgjz6f9	222	6	plasmid	plasmid	NN
cord-273487-nfgjz6f9	222	7	encoding	encode	VBG
cord-273487-nfgjz6f9	222	8	the	the	DT
cord-273487-nfgjz6f9	222	9	105	105	CD
cord-273487-nfgjz6f9	222	10	amino	amino	NN
cord-273487-nfgjz6f9	222	11	acid	acid	NN
cord-273487-nfgjz6f9	222	12	isoform	isoform	NN
cord-273487-nfgjz6f9	222	13	of	of	IN
cord-273487-nfgjz6f9	222	14	WNV	WNV	NNP
cord-273487-nfgjz6f9	222	15	capsid	capsid	NN
cord-273487-nfgjz6f9	222	16	,	,	,
cord-273487-nfgjz6f9	222	17	pCMV5-Capsid	pCMV5-Capsid	NNP
cord-273487-nfgjz6f9	222	18	,	,	,
cord-273487-nfgjz6f9	222	19	has	have	VBZ
cord-273487-nfgjz6f9	222	20	been	be	VBN
cord-273487-nfgjz6f9	222	21	described	describe	VBN
cord-273487-nfgjz6f9	222	22	previously	previously	RB
cord-273487-nfgjz6f9	222	23	.	.	.
cord-273487-nfgjz6f9	223	1	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	224	1	T	T	NNP
cord-273487-nfgjz6f9	224	2	and	and	CC
cord-273487-nfgjz6f9	224	3	A549	a549	JJ
cord-273487-nfgjz6f9	224	4	cells	cell	NNS
cord-273487-nfgjz6f9	224	5	were	be	VBD
cord-273487-nfgjz6f9	224	6	cultured	culture	VBN
cord-273487-nfgjz6f9	224	7	in	in	IN
cord-273487-nfgjz6f9	224	8	DMEM	DMEM	NNP
cord-273487-nfgjz6f9	224	9	supplemented	supplement	VBD
cord-273487-nfgjz6f9	224	10	with	with	IN
cord-273487-nfgjz6f9	224	11	100	100	CD
cord-273487-nfgjz6f9	224	12	U	u	NN
cord-273487-nfgjz6f9	224	13	/	/	SYM
cord-273487-nfgjz6f9	224	14	ml	ml	NN
cord-273487-nfgjz6f9	224	15	penicillin	penicillin	NN
cord-273487-nfgjz6f9	224	16	/	/	SYM
cord-273487-nfgjz6f9	224	17	streptomycin	streptomycin	NNS
cord-273487-nfgjz6f9	224	18	,	,	,
cord-273487-nfgjz6f9	224	19	10	10	CD
cord-273487-nfgjz6f9	224	20	%	%	NN
cord-273487-nfgjz6f9	224	21	heat	heat	NN
cord-273487-nfgjz6f9	224	22	-	-	HYPH
cord-273487-nfgjz6f9	224	23	inactivated	inactivate	VBN
cord-273487-nfgjz6f9	224	24	fetal	fetal	JJ
cord-273487-nfgjz6f9	224	25	bovine	bovine	JJ
cord-273487-nfgjz6f9	224	26	serum	serum	NN
cord-273487-nfgjz6f9	224	27	and	and	CC
cord-273487-nfgjz6f9	224	28	10	10	CD
cord-273487-nfgjz6f9	224	29	mM	mm	CD
cord-273487-nfgjz6f9	224	30	HEPES	HEPES	NNP
cord-273487-nfgjz6f9	224	31	,	,	,
cord-273487-nfgjz6f9	224	32	pH	pH	NNP
cord-273487-nfgjz6f9	224	33	7.4	7.4	CD
cord-273487-nfgjz6f9	224	34	,	,	,
cord-273487-nfgjz6f9	224	35	at	at	IN
cord-273487-nfgjz6f9	224	36	37	37	CD
cord-273487-nfgjz6f9	224	37	1C	1c	NN
cord-273487-nfgjz6f9	224	38	and	and	CC
cord-273487-nfgjz6f9	224	39	5	5	CD
cord-273487-nfgjz6f9	224	40	%	%	NN
cord-273487-nfgjz6f9	224	41	CO	co	NN
cord-273487-nfgjz6f9	224	42	2	2	CD
cord-273487-nfgjz6f9	224	43	.	.	.
cord-273487-nfgjz6f9	225	1	DNA	DNA	NNP
cord-273487-nfgjz6f9	225	2	transfections	transfection	NNS
cord-273487-nfgjz6f9	225	3	were	be	VBD
cord-273487-nfgjz6f9	225	4	performed	perform	VBN
cord-273487-nfgjz6f9	225	5	using	use	VBG
cord-273487-nfgjz6f9	225	6	Perfectin	Perfectin	NNP
cord-273487-nfgjz6f9	225	7	or	or	CC
cord-273487-nfgjz6f9	225	8	TransIT	TransIT	NNP
cord-273487-nfgjz6f9	225	9	s	s	NNP
cord-273487-nfgjz6f9	225	10	-293	-293	NN
cord-273487-nfgjz6f9	225	11	transfection	transfection	NN
cord-273487-nfgjz6f9	225	12	reagent	reagent	NN
cord-273487-nfgjz6f9	225	13	as	as	IN
cord-273487-nfgjz6f9	225	14	described	describe	VBN
cord-273487-nfgjz6f9	225	15	by	by	IN
cord-273487-nfgjz6f9	225	16	the	the	DT
cord-273487-nfgjz6f9	225	17	manufacturers	manufacturer	NNS
cord-273487-nfgjz6f9	225	18	.	.	.
cord-273487-nfgjz6f9	226	1	A549	a549	JJ
cord-273487-nfgjz6f9	226	2	cells	cell	NNS
cord-273487-nfgjz6f9	226	3	grown	grow	VBN
cord-273487-nfgjz6f9	226	4	on	on	IN
cord-273487-nfgjz6f9	226	5	coverslips	coverslip	NNS
cord-273487-nfgjz6f9	226	6	were	be	VBD
cord-273487-nfgjz6f9	226	7	transfected	transfecte	VBN
cord-273487-nfgjz6f9	226	8	with	with	IN
cord-273487-nfgjz6f9	226	9	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	226	10	encoding	encode	VBG
cord-273487-nfgjz6f9	226	11	myc	myc	NNP
cord-273487-nfgjz6f9	226	12	-	-	HYPH
cord-273487-nfgjz6f9	226	13	tagged	tag	VBN
cord-273487-nfgjz6f9	226	14	full	full	JJ
cord-273487-nfgjz6f9	226	15	length	length	NN
cord-273487-nfgjz6f9	226	16	and	and	CC
cord-273487-nfgjz6f9	226	17	truncation	truncation	NN
cord-273487-nfgjz6f9	226	18	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	226	19	constructs	construct	NNS
cord-273487-nfgjz6f9	226	20	.	.	.
cord-273487-nfgjz6f9	227	1	At	at	IN
cord-273487-nfgjz6f9	227	2	24	24	CD
cord-273487-nfgjz6f9	227	3	h	h	NN
cord-273487-nfgjz6f9	227	4	post	post	NN
cord-273487-nfgjz6f9	227	5	-	-	NN
cord-273487-nfgjz6f9	227	6	transfection	transfection	JJ
cord-273487-nfgjz6f9	227	7	,	,	,
cord-273487-nfgjz6f9	227	8	cells	cell	NNS
cord-273487-nfgjz6f9	227	9	were	be	VBD
cord-273487-nfgjz6f9	227	10	infected	infect	VBN
cord-273487-nfgjz6f9	227	11	with	with	IN
cord-273487-nfgjz6f9	227	12	WNV	WNV	NNP
cord-273487-nfgjz6f9	227	13	(	(	-LRB-
cord-273487-nfgjz6f9	227	14	MOI¼5	MOI¼5	NNP
cord-273487-nfgjz6f9	227	15	)	)	-RRB-
cord-273487-nfgjz6f9	227	16	for	for	IN
cord-273487-nfgjz6f9	227	17	24	24	CD
cord-273487-nfgjz6f9	227	18	h	h	NN
cord-273487-nfgjz6f9	227	19	and	and	CC
cord-273487-nfgjz6f9	227	20	then	then	RB
cord-273487-nfgjz6f9	227	21	fixed	fix	VBN
cord-273487-nfgjz6f9	227	22	and	and	CC
cord-273487-nfgjz6f9	227	23	processed	process	VBN
cord-273487-nfgjz6f9	227	24	for	for	IN
cord-273487-nfgjz6f9	227	25	indirect	indirect	JJ
cord-273487-nfgjz6f9	227	26	immunofluorescence	immunofluorescence	NN
cord-273487-nfgjz6f9	227	27	microscopy	microscopy	NN
cord-273487-nfgjz6f9	227	28	.	.	.
cord-273487-nfgjz6f9	228	1	Coverslips	coverslip	NNS
cord-273487-nfgjz6f9	228	2	were	be	VBD
cord-273487-nfgjz6f9	228	3	mounted	mount	VBN
cord-273487-nfgjz6f9	228	4	onto	onto	IN
cord-273487-nfgjz6f9	228	5	microscope	microscope	NN
cord-273487-nfgjz6f9	228	6	slides	slide	NNS
cord-273487-nfgjz6f9	228	7	using	use	VBG
cord-273487-nfgjz6f9	228	8	ProLong	ProLong	NNP
cord-273487-nfgjz6f9	228	9	Gold	Gold	NNP
cord-273487-nfgjz6f9	228	10	antifade	antifade	NN
cord-273487-nfgjz6f9	228	11	reagent	reagent	NN
cord-273487-nfgjz6f9	228	12	with	with	IN
cord-273487-nfgjz6f9	228	13	DAPI	DAPI	NNP
cord-273487-nfgjz6f9	228	14	,	,	,
cord-273487-nfgjz6f9	228	15	after	after	IN
cord-273487-nfgjz6f9	228	16	which	which	WDT
cord-273487-nfgjz6f9	228	17	the	the	DT
cord-273487-nfgjz6f9	228	18	samples	sample	NNS
cord-273487-nfgjz6f9	228	19	were	be	VBD
cord-273487-nfgjz6f9	228	20	examined	examine	VBN
cord-273487-nfgjz6f9	228	21	using	use	VBG
cord-273487-nfgjz6f9	228	22	a	a	DT
cord-273487-nfgjz6f9	228	23	Leica	Leica	NNP
cord-273487-nfgjz6f9	228	24	TCS	TCS	NNP
cord-273487-nfgjz6f9	228	25	SP5	SP5	NNP
cord-273487-nfgjz6f9	228	26	confocal	confocal	JJ
cord-273487-nfgjz6f9	228	27	microscope	microscope	NN
cord-273487-nfgjz6f9	228	28	.	.	.
cord-273487-nfgjz6f9	229	1	In	in	IN
cord-273487-nfgjz6f9	229	2	all	all	DT
cord-273487-nfgjz6f9	229	3	cases	case	NNS
cord-273487-nfgjz6f9	229	4	,	,	,
cord-273487-nfgjz6f9	229	5	samples	sample	NNS
cord-273487-nfgjz6f9	229	6	were	be	VBD
cord-273487-nfgjz6f9	229	7	viewed	view	VBN
cord-273487-nfgjz6f9	229	8	using	use	VBG
cord-273487-nfgjz6f9	229	9	63	63	CD
cord-273487-nfgjz6f9	229	10	Â	â	CD
cord-273487-nfgjz6f9	229	11	objective	objective	JJ
cord-273487-nfgjz6f9	229	12	lens	lens	NN
cord-273487-nfgjz6f9	229	13	and	and	CC
cord-273487-nfgjz6f9	229	14	images	image	NNS
cord-273487-nfgjz6f9	229	15	were	be	VBD
cord-273487-nfgjz6f9	229	16	acquired	acquire	VBN
cord-273487-nfgjz6f9	229	17	using	use	VBG
cord-273487-nfgjz6f9	229	18	identical	identical	JJ
cord-273487-nfgjz6f9	229	19	TCT	TCT	NNP
cord-273487-nfgjz6f9	229	20	TCT	TCT	NNP
cord-273487-nfgjz6f9	229	21	TGC	TGC	NNP
cord-273487-nfgjz6f9	229	22	TGG	TGG	NNP
cord-273487-nfgjz6f9	229	23	TCT	TCT	NNP
cord-273487-nfgjz6f9	229	24	TGC	TGC	NNP
cord-273487-nfgjz6f9	229	25	CAT	cat	NN
cord-273487-nfgjz6f9	230	1	TCC-3	TCC-3	NNP
cord-273487-nfgjz6f9	231	1	qRT	qRT	NNP
cord-273487-nfgjz6f9	231	2	-	-	HYPH
cord-273487-nfgjz6f9	231	3	PCR	PCR	NNP
cord-273487-nfgjz6f9	231	4	exposure	exposure	NN
cord-273487-nfgjz6f9	231	5	times	time	NNS
cord-273487-nfgjz6f9	231	6	for	for	IN
cord-273487-nfgjz6f9	231	7	each	each	DT
cord-273487-nfgjz6f9	231	8	channel	channel	NN
cord-273487-nfgjz6f9	231	9	.	.	.
cord-273487-nfgjz6f9	232	1	Images	image	NNS
cord-273487-nfgjz6f9	232	2	were	be	VBD
cord-273487-nfgjz6f9	232	3	processed	process	VBN
cord-273487-nfgjz6f9	232	4	using	use	VBG
cord-273487-nfgjz6f9	232	5	Image	Image	NNP
cord-273487-nfgjz6f9	232	6	J	J	NNP
cord-273487-nfgjz6f9	232	7	and	and	CC
cord-273487-nfgjz6f9	232	8	LAS	LAS	NNP
cord-273487-nfgjz6f9	232	9	AF	AF	NNP
cord-273487-nfgjz6f9	232	10	Lite	Lite	NNP
cord-273487-nfgjz6f9	232	11	software	software	NN
cord-273487-nfgjz6f9	232	12	.	.	.
cord-273487-nfgjz6f9	233	1	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	233	2	T	t	NN
cord-273487-nfgjz6f9	233	3	cells	cell	NNS
cord-273487-nfgjz6f9	233	4	(	(	-LRB-
cord-273487-nfgjz6f9	233	5	1.2	1.2	CD
cord-273487-nfgjz6f9	233	6	Â	â	CD
cord-273487-nfgjz6f9	233	7	10	10	CD
cord-273487-nfgjz6f9	233	8	6	6	CD
cord-273487-nfgjz6f9	233	9	)	)	-RRB-
cord-273487-nfgjz6f9	233	10	were	be	VBD
cord-273487-nfgjz6f9	233	11	seeded	seed	VBN
cord-273487-nfgjz6f9	233	12	into	into	IN
cord-273487-nfgjz6f9	233	13	100-mm	100-mm	CD
cord-273487-nfgjz6f9	233	14	-	-	HYPH
cord-273487-nfgjz6f9	233	15	diameter	diameter	NN
cord-273487-nfgjz6f9	233	16	dishes	dish	NNS
cord-273487-nfgjz6f9	233	17	and	and	CC
cord-273487-nfgjz6f9	233	18	the	the	DT
cord-273487-nfgjz6f9	233	19	next	next	JJ
cord-273487-nfgjz6f9	233	20	day	day	NN
cord-273487-nfgjz6f9	233	21	,	,	,
cord-273487-nfgjz6f9	233	22	were	be	VBD
cord-273487-nfgjz6f9	233	23	transfected	transfecte	VBN
cord-273487-nfgjz6f9	233	24	with	with	IN
cord-273487-nfgjz6f9	233	25	expression	expression	NN
cord-273487-nfgjz6f9	233	26	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	233	27	(	(	-LRB-
cord-273487-nfgjz6f9	233	28	8	8	CD
cord-273487-nfgjz6f9	233	29	mg	mg	CD
cord-273487-nfgjz6f9	233	30	)	)	-RRB-
cord-273487-nfgjz6f9	233	31	using	use	VBG
cord-273487-nfgjz6f9	233	32	PerFectin	PerFectin	NNP
cord-273487-nfgjz6f9	233	33	.	.	.
cord-273487-nfgjz6f9	234	1	After	after	IN
cord-273487-nfgjz6f9	234	2	48	48	CD
cord-273487-nfgjz6f9	234	3	h	h	NN
cord-273487-nfgjz6f9	234	4	,	,	,
cord-273487-nfgjz6f9	234	5	cells	cell	NNS
cord-273487-nfgjz6f9	234	6	were	be	VBD
cord-273487-nfgjz6f9	234	7	washed	wash	VBN
cord-273487-nfgjz6f9	234	8	with	with	IN
cord-273487-nfgjz6f9	234	9	phosphate	phosphate	NN
cord-273487-nfgjz6f9	234	10	-	-	HYPH
cord-273487-nfgjz6f9	234	11	buffered	buffer	VBN
cord-273487-nfgjz6f9	234	12	saline	saline	NN
cord-273487-nfgjz6f9	234	13	(	(	-LRB-
cord-273487-nfgjz6f9	234	14	PBS	PBS	NNP
cord-273487-nfgjz6f9	234	15	)	)	-RRB-
cord-273487-nfgjz6f9	234	16	and	and	CC
cord-273487-nfgjz6f9	234	17	then	then	RB
cord-273487-nfgjz6f9	234	18	lysed	lyse	VBN
cord-273487-nfgjz6f9	234	19	with	with	IN
cord-273487-nfgjz6f9	234	20	NP-40	NP-40	NNP
cord-273487-nfgjz6f9	234	21	lysis	lysis	NN
cord-273487-nfgjz6f9	234	22	buffer	buffer	NN
cord-273487-nfgjz6f9	234	23	(	(	-LRB-
cord-273487-nfgjz6f9	234	24	150	150	CD
cord-273487-nfgjz6f9	234	25	mM	mm	CD
cord-273487-nfgjz6f9	234	26	NaCl	nacl	NN
cord-273487-nfgjz6f9	234	27	,	,	,
cord-273487-nfgjz6f9	234	28	2	2	CD
cord-273487-nfgjz6f9	234	29	mM	mm	CD
cord-273487-nfgjz6f9	234	30	EDTA	EDTA	NNP
cord-273487-nfgjz6f9	234	31	,	,	,
cord-273487-nfgjz6f9	234	32	1	1	CD
cord-273487-nfgjz6f9	234	33	%	%	NN
cord-273487-nfgjz6f9	234	34	non	non	JJ
cord-273487-nfgjz6f9	234	35	-	-	JJ
cord-273487-nfgjz6f9	234	36	idet	idet	JJ
cord-273487-nfgjz6f9	234	37	P-40	P-40	NNP
cord-273487-nfgjz6f9	234	38	,	,	,
cord-273487-nfgjz6f9	234	39	50	50	CD
cord-273487-nfgjz6f9	234	40	mM	mm	CD
cord-273487-nfgjz6f9	234	41	Tris	Tris	NNP
cord-273487-nfgjz6f9	234	42	-	-	HYPH
cord-273487-nfgjz6f9	234	43	HCl	HCl	NNP
cord-273487-nfgjz6f9	234	44	[	[	-LRB-
cord-273487-nfgjz6f9	234	45	pH	pH	NNP
cord-273487-nfgjz6f9	234	46	7.2	7.2	CD
cord-273487-nfgjz6f9	234	47	]	]	-RRB-
cord-273487-nfgjz6f9	234	48	,	,	,
cord-273487-nfgjz6f9	234	49	1	1	CD
cord-273487-nfgjz6f9	234	50	mM	mm	CD
cord-273487-nfgjz6f9	234	51	fresh	fresh	JJ
cord-273487-nfgjz6f9	234	52	dithiothreitol	dithiothreitol	NN
cord-273487-nfgjz6f9	234	53	)	)	-RRB-
cord-273487-nfgjz6f9	234	54	containing	contain	VBG
cord-273487-nfgjz6f9	234	55	protease	protease	NN
cord-273487-nfgjz6f9	234	56	inhibitors	inhibitor	NNS
cord-273487-nfgjz6f9	234	57	on	on	IN
cord-273487-nfgjz6f9	234	58	ice	ice	NN
cord-273487-nfgjz6f9	234	59	for	for	IN
cord-273487-nfgjz6f9	234	60	30	30	CD
cord-273487-nfgjz6f9	234	61	min	min	NN
cord-273487-nfgjz6f9	234	62	.	.	.
cord-273487-nfgjz6f9	235	1	Lysates	Lysates	NNP
cord-273487-nfgjz6f9	235	2	were	be	VBD
cord-273487-nfgjz6f9	235	3	clarified	clarify	VBN
cord-273487-nfgjz6f9	235	4	by	by	IN
cord-273487-nfgjz6f9	235	5	centrifugation	centrifugation	NN
cord-273487-nfgjz6f9	235	6	for	for	IN
cord-273487-nfgjz6f9	235	7	10	10	CD
cord-273487-nfgjz6f9	235	8	min	min	NN
cord-273487-nfgjz6f9	235	9	at	at	IN
cord-273487-nfgjz6f9	235	10	14,000	14,000	CD
cord-273487-nfgjz6f9	235	11	rpm	rpm	NN
cord-273487-nfgjz6f9	235	12	in	in	IN
cord-273487-nfgjz6f9	235	13	a	a	DT
cord-273487-nfgjz6f9	235	14	microcentrifuge	microcentrifuge	NN
cord-273487-nfgjz6f9	235	15	at	at	IN
cord-273487-nfgjz6f9	235	16	4	4	CD
cord-273487-nfgjz6f9	235	17	1C.	1c.	CD
cord-273487-nfgjz6f9	235	18	Small	small	JJ
cord-273487-nfgjz6f9	235	19	aliquots	aliquot	NNS
cord-273487-nfgjz6f9	235	20	of	of	IN
cord-273487-nfgjz6f9	235	21	the	the	DT
cord-273487-nfgjz6f9	235	22	clarified	clarify	VBN
cord-273487-nfgjz6f9	235	23	lysates	lysate	NNS
cord-273487-nfgjz6f9	235	24	were	be	VBD
cord-273487-nfgjz6f9	235	25	kept	keep	VBN
cord-273487-nfgjz6f9	235	26	for	for	IN
cord-273487-nfgjz6f9	235	27	loading	loading	NN
cord-273487-nfgjz6f9	235	28	controls	control	NNS
cord-273487-nfgjz6f9	235	29	.	.	.
cord-273487-nfgjz6f9	236	1	The	the	DT
cord-273487-nfgjz6f9	236	2	remaining	remain	VBG
cord-273487-nfgjz6f9	236	3	lysates	lysate	NNS
cord-273487-nfgjz6f9	236	4	were	be	VBD
cord-273487-nfgjz6f9	236	5	precleared	precleare	VBN
cord-273487-nfgjz6f9	236	6	with	with	IN
cord-273487-nfgjz6f9	236	7	Protein	Protein	NNP
cord-273487-nfgjz6f9	236	8	A	A	NNP
cord-273487-nfgjz6f9	236	9	-	-	:
cord-273487-nfgjz6f9	236	10	or	or	CC
cord-273487-nfgjz6f9	236	11	G	g	NN
cord-273487-nfgjz6f9	236	12	-	-	HYPH
cord-273487-nfgjz6f9	236	13	Sepharose	Sepharose	NNP
cord-273487-nfgjz6f9	236	14	beads	bead	NNS
cord-273487-nfgjz6f9	236	15	for	for	IN
cord-273487-nfgjz6f9	236	16	1	1	CD
cord-273487-nfgjz6f9	236	17	h	h	NN
cord-273487-nfgjz6f9	236	18	at	at	IN
cord-273487-nfgjz6f9	236	19	4	4	CD
cord-273487-nfgjz6f9	236	20	1C	1c	NN
cord-273487-nfgjz6f9	236	21	before	before	IN
cord-273487-nfgjz6f9	236	22	sequential	sequential	JJ
cord-273487-nfgjz6f9	236	23	incubation	incubation	NN
cord-273487-nfgjz6f9	236	24	with	with	IN
cord-273487-nfgjz6f9	236	25	mouse	mouse	NN
cord-273487-nfgjz6f9	236	26	anti	anti	JJ
cord-273487-nfgjz6f9	236	27	-	-	JJ
cord-273487-nfgjz6f9	236	28	myc	myc	JJ
cord-273487-nfgjz6f9	236	29	antibodies	antibody	NNS
cord-273487-nfgjz6f9	236	30	for	for	IN
cord-273487-nfgjz6f9	236	31	3	3	CD
cord-273487-nfgjz6f9	236	32	h	h	NN
cord-273487-nfgjz6f9	236	33	and	and	CC
cord-273487-nfgjz6f9	236	34	then	then	RB
cord-273487-nfgjz6f9	236	35	Protein	Protein	NNP
cord-273487-nfgjz6f9	236	36	A	A	NNP
cord-273487-nfgjz6f9	236	37	-	-	:
cord-273487-nfgjz6f9	236	38	or	or	CC
cord-273487-nfgjz6f9	236	39	G	g	NN
cord-273487-nfgjz6f9	236	40	-	-	HYPH
cord-273487-nfgjz6f9	236	41	Sepharose	Sepharose	NNP
cord-273487-nfgjz6f9	236	42	beads	bead	NNS
cord-273487-nfgjz6f9	236	43	for	for	IN
cord-273487-nfgjz6f9	236	44	2	2	CD
cord-273487-nfgjz6f9	236	45	h	h	NN
cord-273487-nfgjz6f9	236	46	at	at	IN
cord-273487-nfgjz6f9	236	47	4	4	CD
cord-273487-nfgjz6f9	236	48	1C.	1c.	CD
cord-273487-nfgjz6f9	237	1	For	for	IN
cord-273487-nfgjz6f9	237	2	the	the	DT
cord-273487-nfgjz6f9	237	3	GST	GST	NNP
cord-273487-nfgjz6f9	237	4	pull	pull	VB
cord-273487-nfgjz6f9	237	5	-	-	HYPH
cord-273487-nfgjz6f9	237	6	down	down	RP
cord-273487-nfgjz6f9	237	7	experiments	experiment	NNS
cord-273487-nfgjz6f9	237	8	,	,	,
cord-273487-nfgjz6f9	237	9	cleared	clear	VBN
cord-273487-nfgjz6f9	237	10	lysates	lysate	NNS
cord-273487-nfgjz6f9	237	11	were	be	VBD
cord-273487-nfgjz6f9	237	12	incubated	incubate	VBN
cord-273487-nfgjz6f9	237	13	with	with	IN
cord-273487-nfgjz6f9	237	14	glutathione	glutathione	NN
cord-273487-nfgjz6f9	237	15	-	-	:
cord-273487-nfgjz6f9	237	16	Sepharose	Sepharose	NNP
cord-273487-nfgjz6f9	237	17	4B	4b	NN
cord-273487-nfgjz6f9	237	18	beads	bead	NNS
cord-273487-nfgjz6f9	237	19	for	for	IN
cord-273487-nfgjz6f9	237	20	2	2	CD
cord-273487-nfgjz6f9	237	21	h	h	NN
cord-273487-nfgjz6f9	237	22	at	at	IN
cord-273487-nfgjz6f9	237	23	4	4	CD
cord-273487-nfgjz6f9	237	24	1C.	1c.	CD
cord-273487-nfgjz6f9	237	25	Immunoprecipitates	Immunoprecipitates	NNPS
cord-273487-nfgjz6f9	237	26	and	and	CC
cord-273487-nfgjz6f9	237	27	GST	GST	NNP
cord-273487-nfgjz6f9	237	28	pull	pull	NN
cord-273487-nfgjz6f9	237	29	-	-	HYPH
cord-273487-nfgjz6f9	237	30	downs	down	NNS
cord-273487-nfgjz6f9	237	31	were	be	VBD
cord-273487-nfgjz6f9	237	32	washed	wash	VBN
cord-273487-nfgjz6f9	237	33	three	three	CD
cord-273487-nfgjz6f9	237	34	times	time	NNS
cord-273487-nfgjz6f9	237	35	with	with	IN
cord-273487-nfgjz6f9	237	36	lysis	lysis	NN
cord-273487-nfgjz6f9	237	37	buffer	buffer	NN
cord-273487-nfgjz6f9	237	38	before	before	IN
cord-273487-nfgjz6f9	237	39	the	the	DT
cord-273487-nfgjz6f9	237	40	bound	bind	VBN
cord-273487-nfgjz6f9	237	41	proteins	protein	NNS
cord-273487-nfgjz6f9	237	42	were	be	VBD
cord-273487-nfgjz6f9	237	43	eluted	elute	VBN
cord-273487-nfgjz6f9	237	44	by	by	IN
cord-273487-nfgjz6f9	237	45	boiling	boil	VBG
cord-273487-nfgjz6f9	237	46	in	in	IN
cord-273487-nfgjz6f9	237	47	protein	protein	NN
cord-273487-nfgjz6f9	237	48	sample	sample	NN
cord-273487-nfgjz6f9	237	49	buffer	buffer	NN
cord-273487-nfgjz6f9	237	50	.	.	.
cord-273487-nfgjz6f9	238	1	Proteins	protein	NNS
cord-273487-nfgjz6f9	238	2	were	be	VBD
cord-273487-nfgjz6f9	238	3	separated	separate	VBN
cord-273487-nfgjz6f9	238	4	by	by	IN
cord-273487-nfgjz6f9	238	5	SDS	SDS	NNP
cord-273487-nfgjz6f9	238	6	-	-	HYPH
cord-273487-nfgjz6f9	238	7	PAGE	PAGE	NNP
cord-273487-nfgjz6f9	238	8	and	and	CC
cord-273487-nfgjz6f9	238	9	transferred	transfer	VBD
cord-273487-nfgjz6f9	238	10	to	to	IN
cord-273487-nfgjz6f9	238	11	polyvinylidene	polyvinylidene	NN
cord-273487-nfgjz6f9	238	12	difluoride	difluoride	NN
cord-273487-nfgjz6f9	238	13	membranes	membrane	NNS
cord-273487-nfgjz6f9	238	14	for	for	IN
cord-273487-nfgjz6f9	238	15	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	238	16	.	.	.
cord-273487-nfgjz6f9	239	1	Stable	stable	JJ
cord-273487-nfgjz6f9	239	2	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	239	3	T	t	NN
cord-273487-nfgjz6f9	239	4	cell	cell	NN
cord-273487-nfgjz6f9	239	5	lines	line	NNS
cord-273487-nfgjz6f9	239	6	expressing	express	VBG
cord-273487-nfgjz6f9	239	7	a	a	DT
cord-273487-nfgjz6f9	239	8	DDX56-specific	ddx56-specific	NN
cord-273487-nfgjz6f9	240	1	(	(	-LRB-
cord-273487-nfgjz6f9	240	2	Clone	clone	NN
cord-273487-nfgjz6f9	241	1	i	i	PRP
cord-273487-nfgjz6f9	242	1	d	d	LS
cord-273487-nfgjz6f9	242	2	V3LHS_353980	V3LHS_353980	NNP
cord-273487-nfgjz6f9	242	3	Open	Open	NNP
cord-273487-nfgjz6f9	242	4	Biosystems	Biosystems	NNP
cord-273487-nfgjz6f9	242	5	)	)	-RRB-
cord-273487-nfgjz6f9	242	6	or	or	CC
cord-273487-nfgjz6f9	242	7	a	a	DT
cord-273487-nfgjz6f9	242	8	non	non	NN
cord-273487-nfgjz6f9	242	9	-	-	JJ
cord-273487-nfgjz6f9	242	10	silencing	silencing	JJ
cord-273487-nfgjz6f9	242	11	shRNAmir	shrnamir	NN
cord-273487-nfgjz6f9	242	12	(	(	-LRB-
cord-273487-nfgjz6f9	242	13	catalog	catalog	NN
cord-273487-nfgjz6f9	242	14	number	number	NN
cord-273487-nfgjz6f9	242	15	RHS4346	RHS4346	NNP
cord-273487-nfgjz6f9	242	16	;	;	:
cord-273487-nfgjz6f9	242	17	Open	Open	NNP
cord-273487-nfgjz6f9	242	18	Biosystems	Biosystems	NNP
cord-273487-nfgjz6f9	242	19	)	)	-RRB-
cord-273487-nfgjz6f9	242	20	were	be	VBD
cord-273487-nfgjz6f9	242	21	created	create	VBN
cord-273487-nfgjz6f9	242	22	by	by	IN
cord-273487-nfgjz6f9	242	23	lentiviral	lentiviral	NNP
cord-273487-nfgjz6f9	242	24	transduction	transduction	NN
cord-273487-nfgjz6f9	242	25	followed	follow	VBN
cord-273487-nfgjz6f9	242	26	by	by	IN
cord-273487-nfgjz6f9	242	27	puromycin	puromycin	NNS
cord-273487-nfgjz6f9	242	28	selection	selection	NN
cord-273487-nfgjz6f9	242	29	(	(	-LRB-
cord-273487-nfgjz6f9	242	30	1	1	CD
cord-273487-nfgjz6f9	242	31	mg	mg	NNP
cord-273487-nfgjz6f9	242	32	/	/	SYM
cord-273487-nfgjz6f9	242	33	ml	ml	NNP
cord-273487-nfgjz6f9	242	34	)	)	-RRB-
cord-273487-nfgjz6f9	242	35	as	as	IN
cord-273487-nfgjz6f9	242	36	described	describe	VBN
cord-273487-nfgjz6f9	242	37	(	(	-LRB-
cord-273487-nfgjz6f9	242	38	Xu	Xu	NNP
cord-273487-nfgjz6f9	242	39	et	et	NNP
cord-273487-nfgjz6f9	242	40	al	al	NNP
cord-273487-nfgjz6f9	242	41	.	.	NNP
cord-273487-nfgjz6f9	242	42	,	,	,
cord-273487-nfgjz6f9	242	43	2011	2011	CD
cord-273487-nfgjz6f9	242	44	)	)	-RRB-
cord-273487-nfgjz6f9	242	45	.	.	.
cord-273487-nfgjz6f9	243	1	After	after	IN
cord-273487-nfgjz6f9	243	2	selection	selection	NN
cord-273487-nfgjz6f9	243	3	,	,	,
cord-273487-nfgjz6f9	243	4	the	the	DT
cord-273487-nfgjz6f9	243	5	resulting	result	VBG
cord-273487-nfgjz6f9	243	6	polyclonal	polyclonal	JJ
cord-273487-nfgjz6f9	243	7	cell	cell	NN
cord-273487-nfgjz6f9	243	8	lines	line	NNS
cord-273487-nfgjz6f9	243	9	were	be	VBD
cord-273487-nfgjz6f9	243	10	maintained	maintain	VBN
cord-273487-nfgjz6f9	243	11	in	in	IN
cord-273487-nfgjz6f9	243	12	media	medium	NNS
cord-273487-nfgjz6f9	243	13	containing	contain	VBG
cord-273487-nfgjz6f9	243	14	0.25	0.25	CD
cord-273487-nfgjz6f9	243	15	mg	mg	NNP
cord-273487-nfgjz6f9	243	16	/	/	SYM
cord-273487-nfgjz6f9	243	17	ml	ml	NN
cord-273487-nfgjz6f9	243	18	puromycin	puromycin	NNS
cord-273487-nfgjz6f9	243	19	.	.	.
cord-273487-nfgjz6f9	244	1	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	244	2	T	t	NN
cord-273487-nfgjz6f9	244	3	cells	cell	NNS
cord-273487-nfgjz6f9	244	4	(	(	-LRB-
cord-273487-nfgjz6f9	244	5	2.5	2.5	CD
cord-273487-nfgjz6f9	244	6	Â	â	CD
cord-273487-nfgjz6f9	244	7	10	10	CD
cord-273487-nfgjz6f9	244	8	6	6	CD
cord-273487-nfgjz6f9	244	9	)	)	-RRB-
cord-273487-nfgjz6f9	244	10	in	in	IN
cord-273487-nfgjz6f9	244	11	100	100	CD
cord-273487-nfgjz6f9	244	12	mm	mm	NNS
cord-273487-nfgjz6f9	244	13	dishes	dish	NNS
cord-273487-nfgjz6f9	244	14	were	be	VBD
cord-273487-nfgjz6f9	244	15	cotransfected	cotransfecte	VBN
cord-273487-nfgjz6f9	244	16	with	with	IN
cord-273487-nfgjz6f9	244	17	pTRIP	ptrip	JJ
cord-273487-nfgjz6f9	244	18	-	-	HYPH
cord-273487-nfgjz6f9	244	19	AcGFP	AcGFP	NNP
cord-273487-nfgjz6f9	244	20	plasmids	plasmid	NNS
cord-273487-nfgjz6f9	244	21	encoding	encode	VBG
cord-273487-nfgjz6f9	244	22	myc	myc	NNP
cord-273487-nfgjz6f9	244	23	-	-	HYPH
cord-273487-nfgjz6f9	244	24	tagged	tag	VBN
cord-273487-nfgjz6f9	244	25	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	244	26	cDNAs	cDNAs	.
cord-273487-nfgjz6f9	245	1	(	(	-LRB-
cord-273487-nfgjz6f9	245	2	WT	WT	NNP
cord-273487-nfgjz6f9	245	3	,	,	,
cord-273487-nfgjz6f9	245	4	D166N	D166N	NNP
cord-273487-nfgjz6f9	245	5	,	,	,
cord-273487-nfgjz6f9	245	6	E167Q	E167Q	NNP
cord-273487-nfgjz6f9	245	7	,	,	,
cord-273487-nfgjz6f9	245	8	NT	NT	NNP
cord-273487-nfgjz6f9	245	9	or	or	CC
cord-273487-nfgjz6f9	245	10	CT	CT	NNP
cord-273487-nfgjz6f9	245	11	)	)	-RRB-
cord-273487-nfgjz6f9	245	12	,	,	,
cord-273487-nfgjz6f9	245	13	pGag	pgag	JJ
cord-273487-nfgjz6f9	245	14	-	-	HYPH
cord-273487-nfgjz6f9	245	15	Pol	pol	NN
cord-273487-nfgjz6f9	245	16	(	(	-LRB-
cord-273487-nfgjz6f9	245	17	5.6	5.6	CD
cord-273487-nfgjz6f9	245	18	mg	mg	NNP
cord-273487-nfgjz6f9	245	19	)	)	-RRB-
cord-273487-nfgjz6f9	245	20	and	and	CC
cord-273487-nfgjz6f9	245	21	pHCMV	phcmv	NN
cord-273487-nfgjz6f9	245	22	-	-	HYPH
cord-273487-nfgjz6f9	245	23	VSVG	VSVG	NNP
cord-273487-nfgjz6f9	245	24	(	(	-LRB-
cord-273487-nfgjz6f9	245	25	1.6	1.6	CD
cord-273487-nfgjz6f9	245	26	mg	mg	NN
cord-273487-nfgjz6f9	245	27	)	)	-RRB-
cord-273487-nfgjz6f9	246	1	using	use	VBG
cord-273487-nfgjz6f9	246	2	TransIT	TransIT	NNP
cord-273487-nfgjz6f9	246	3	s	s	NNP
cord-273487-nfgjz6f9	246	4	-293	-293	NN
cord-273487-nfgjz6f9	246	5	transfection	transfection	NN
cord-273487-nfgjz6f9	246	6	reagent	reagent	NN
cord-273487-nfgjz6f9	246	7	.	.	.
cord-273487-nfgjz6f9	247	1	Forty	forty	CD
cord-273487-nfgjz6f9	247	2	-	-	HYPH
cord-273487-nfgjz6f9	247	3	eight	eight	CD
cord-273487-nfgjz6f9	247	4	hours	hour	NNS
cord-273487-nfgjz6f9	247	5	later	later	RB
cord-273487-nfgjz6f9	247	6	,	,	,
cord-273487-nfgjz6f9	247	7	polybrene	polybrene	NNP
cord-273487-nfgjz6f9	247	8	(	(	-LRB-
cord-273487-nfgjz6f9	247	9	4	4	CD
cord-273487-nfgjz6f9	247	10	mg	mg	NNP
cord-273487-nfgjz6f9	247	11	/	/	SYM
cord-273487-nfgjz6f9	247	12	ml	ml	NNP
cord-273487-nfgjz6f9	247	13	)	)	-RRB-
cord-273487-nfgjz6f9	247	14	and	and	CC
cord-273487-nfgjz6f9	247	15	HEPES	HEPES	NNP
cord-273487-nfgjz6f9	247	16	(	(	-LRB-
cord-273487-nfgjz6f9	247	17	20	20	CD
cord-273487-nfgjz6f9	247	18	mM	mm	CD
cord-273487-nfgjz6f9	247	19	)	)	-RRB-
cord-273487-nfgjz6f9	247	20	were	be	VBD
cord-273487-nfgjz6f9	247	21	added	add	VBN
cord-273487-nfgjz6f9	247	22	to	to	IN
cord-273487-nfgjz6f9	247	23	the	the	DT
cord-273487-nfgjz6f9	247	24	lentivirus	lentivirus	NN
cord-273487-nfgjz6f9	247	25	-	-	HYPH
cord-273487-nfgjz6f9	247	26	containing	contain	VBG
cord-273487-nfgjz6f9	247	27	culture	culture	NN
cord-273487-nfgjz6f9	247	28	supernatants	supernatant	NNS
cord-273487-nfgjz6f9	247	29	which	which	WDT
cord-273487-nfgjz6f9	247	30	were	be	VBD
cord-273487-nfgjz6f9	247	31	then	then	RB
cord-273487-nfgjz6f9	247	32	passed	pass	VBN
cord-273487-nfgjz6f9	247	33	through	through	IN
cord-273487-nfgjz6f9	247	34	0.45	0.45	CD
cord-273487-nfgjz6f9	247	35	mm	mm	NN
cord-273487-nfgjz6f9	247	36	filter	filter	NN
cord-273487-nfgjz6f9	247	37	before	before	IN
cord-273487-nfgjz6f9	247	38	aliquotting	aliquotting	NN
cord-273487-nfgjz6f9	247	39	.	.	.
cord-273487-nfgjz6f9	248	1	Stocks	stock	NNS
cord-273487-nfgjz6f9	248	2	were	be	VBD
cord-273487-nfgjz6f9	248	3	stored	store	VBN
cord-273487-nfgjz6f9	248	4	at	at	IN
cord-273487-nfgjz6f9	248	5	À	à	NN
cord-273487-nfgjz6f9	248	6	80	80	CD
cord-273487-nfgjz6f9	248	7	1C	1c	NN
cord-273487-nfgjz6f9	248	8	or	or	CC
cord-273487-nfgjz6f9	248	9	used	use	VBD
cord-273487-nfgjz6f9	248	10	immediately	immediately	RB
cord-273487-nfgjz6f9	248	11	to	to	TO
cord-273487-nfgjz6f9	248	12	transduce	transduce	VB
cord-273487-nfgjz6f9	248	13	HEK293	HEK293	NNP
cord-273487-nfgjz6f9	248	14	T	t	NN
cord-273487-nfgjz6f9	248	15	or	or	CC
cord-273487-nfgjz6f9	248	16	A549	a549	JJ
cord-273487-nfgjz6f9	248	17	cells	cell	NNS
cord-273487-nfgjz6f9	248	18	.	.	.
cord-273487-nfgjz6f9	249	1	Typically	typically	RB
cord-273487-nfgjz6f9	249	2	,	,	,
cord-273487-nfgjz6f9	249	3	lentiviral	lentiviral	JJ
cord-273487-nfgjz6f9	249	4	stocks	stock	NNS
cord-273487-nfgjz6f9	249	5	were	be	VBD
cord-273487-nfgjz6f9	249	6	diluted	dilute	VBN
cord-273487-nfgjz6f9	249	7	1:10	1:10	CD
cord-273487-nfgjz6f9	249	8	in	in	IN
cord-273487-nfgjz6f9	249	9	DMEM	DMEM	NNP
cord-273487-nfgjz6f9	249	10	containing	contain	VBG
cord-273487-nfgjz6f9	249	11	3	3	CD
cord-273487-nfgjz6f9	249	12	%	%	NN
cord-273487-nfgjz6f9	249	13	FBS	FBS	NNP
cord-273487-nfgjz6f9	249	14	,	,	,
cord-273487-nfgjz6f9	249	15	polybrene	polybrene	NN
cord-273487-nfgjz6f9	249	16	(	(	-LRB-
cord-273487-nfgjz6f9	249	17	4	4	CD
cord-273487-nfgjz6f9	249	18	mg	mg	NNP
cord-273487-nfgjz6f9	249	19	/	/	SYM
cord-273487-nfgjz6f9	249	20	ml	ml	NNP
cord-273487-nfgjz6f9	249	21	)	)	-RRB-
cord-273487-nfgjz6f9	249	22	and	and	CC
cord-273487-nfgjz6f9	249	23	HEPES	HEPES	NNP
cord-273487-nfgjz6f9	249	24	(	(	-LRB-
cord-273487-nfgjz6f9	249	25	20	20	CD
cord-273487-nfgjz6f9	249	26	mM	mm	CD
cord-273487-nfgjz6f9	249	27	)	)	-RRB-
cord-273487-nfgjz6f9	249	28	.	.	.
cord-273487-nfgjz6f9	250	1	Cells	cell	NNS
cord-273487-nfgjz6f9	250	2	were	be	VBD
cord-273487-nfgjz6f9	250	3	then	then	RB
cord-273487-nfgjz6f9	250	4	spinoculated	spinoculate	VBN
cord-273487-nfgjz6f9	250	5	by	by	IN
cord-273487-nfgjz6f9	250	6	centrifugation	centrifugation	NN
cord-273487-nfgjz6f9	250	7	at	at	IN
cord-273487-nfgjz6f9	250	8	1200	1200	CD
cord-273487-nfgjz6f9	250	9	rpm	rpm	NN
cord-273487-nfgjz6f9	250	10	in	in	IN
cord-273487-nfgjz6f9	250	11	an	an	DT
cord-273487-nfgjz6f9	250	12	Eppendorf	Eppendorf	NNP
cord-273487-nfgjz6f9	250	13	A-4	A-4	NNP
cord-273487-nfgjz6f9	250	14	-	-	HYPH
cord-273487-nfgjz6f9	250	15	62	62	CD
cord-273487-nfgjz6f9	250	16	rotor	rotor	NN
cord-273487-nfgjz6f9	250	17	for	for	IN
cord-273487-nfgjz6f9	250	18	1	1	CD
cord-273487-nfgjz6f9	250	19	h	h	NN
cord-273487-nfgjz6f9	250	20	at	at	IN
cord-273487-nfgjz6f9	250	21	37	37	CD
cord-273487-nfgjz6f9	250	22	1C	1c	NN
cord-273487-nfgjz6f9	250	23	after	after	IN
cord-273487-nfgjz6f9	250	24	which	which	WDT
cord-273487-nfgjz6f9	250	25	the	the	DT
cord-273487-nfgjz6f9	250	26	plates	plate	NNS
cord-273487-nfgjz6f9	250	27	were	be	VBD
cord-273487-nfgjz6f9	250	28	transferred	transfer	VBN
cord-273487-nfgjz6f9	250	29	to	to	IN
cord-273487-nfgjz6f9	250	30	a	a	DT
cord-273487-nfgjz6f9	250	31	37	37	CD
cord-273487-nfgjz6f9	250	32	1C	1c	NN
cord-273487-nfgjz6f9	250	33	incubator	incubator	NN
cord-273487-nfgjz6f9	250	34	.	.	.
cord-273487-nfgjz6f9	251	1	After	after	IN
cord-273487-nfgjz6f9	251	2	6	6	CD
cord-273487-nfgjz6f9	251	3	h	h	NN
cord-273487-nfgjz6f9	251	4	,	,	,
cord-273487-nfgjz6f9	251	5	the	the	DT
cord-273487-nfgjz6f9	251	6	media	medium	NNS
cord-273487-nfgjz6f9	251	7	were	be	VBD
cord-273487-nfgjz6f9	251	8	replaced	replace	VBN
cord-273487-nfgjz6f9	251	9	with	with	IN
cord-273487-nfgjz6f9	251	10	DMEM	DMEM	NNP
cord-273487-nfgjz6f9	251	11	containing	contain	VBG
cord-273487-nfgjz6f9	251	12	10	10	CD
cord-273487-nfgjz6f9	251	13	%	%	NN
cord-273487-nfgjz6f9	251	14	FBS	FBS	NNP
cord-273487-nfgjz6f9	251	15	.	.	.
cord-273487-nfgjz6f9	252	1	Unless	unless	IN
cord-273487-nfgjz6f9	252	2	otherwise	otherwise	RB
cord-273487-nfgjz6f9	252	3	indicated	indicate	VBN
cord-273487-nfgjz6f9	252	4	,	,	,
cord-273487-nfgjz6f9	252	5	transduced	transduce	VBN
cord-273487-nfgjz6f9	252	6	cells	cell	NNS
cord-273487-nfgjz6f9	252	7	were	be	VBD
cord-273487-nfgjz6f9	252	8	analyzed	analyze	VBN
cord-273487-nfgjz6f9	252	9	48	48	CD
cord-273487-nfgjz6f9	252	10	h	h	NN
cord-273487-nfgjz6f9	252	11	posttransduction	posttransduction	NN
cord-273487-nfgjz6f9	252	12	.	.	.
cord-273487-nfgjz6f9	253	1	WNV	WNV	NNP
cord-273487-nfgjz6f9	253	2	strain	strain	NN
cord-273487-nfgjz6f9	254	1	NY99	NY99	NNP
cord-273487-nfgjz6f9	254	2	was	be	VBD
cord-273487-nfgjz6f9	254	3	kindly	kindly	RB
cord-273487-nfgjz6f9	254	4	provided	provide	VBN
cord-273487-nfgjz6f9	254	5	by	by	IN
cord-273487-nfgjz6f9	254	6	Mike	Mike	NNP
cord-273487-nfgjz6f9	254	7	Drebot	Drebot	NNP
cord-273487-nfgjz6f9	254	8	(	(	-LRB-
cord-273487-nfgjz6f9	254	9	Public	Public	NNP
cord-273487-nfgjz6f9	254	10	Health	Health	NNP
cord-273487-nfgjz6f9	254	11	Agency	Agency	NNP
cord-273487-nfgjz6f9	254	12	of	of	IN
cord-273487-nfgjz6f9	254	13	Canada	Canada	NNP
cord-273487-nfgjz6f9	254	14	,	,	,
cord-273487-nfgjz6f9	254	15	Winnipeg	Winnipeg	NNP
cord-273487-nfgjz6f9	254	16	,	,	,
cord-273487-nfgjz6f9	254	17	MB	MB	NNP
cord-273487-nfgjz6f9	254	18	)	)	-RRB-
cord-273487-nfgjz6f9	254	19	.	.	.
cord-273487-nfgjz6f9	255	1	All	all	DT
cord-273487-nfgjz6f9	255	2	virus	virus	NN
cord-273487-nfgjz6f9	255	3	manipulations	manipulation	NNS
cord-273487-nfgjz6f9	255	4	were	be	VBD
cord-273487-nfgjz6f9	255	5	performed	perform	VBN
cord-273487-nfgjz6f9	255	6	under	under	IN
cord-273487-nfgjz6f9	255	7	level	level	NN
cord-273487-nfgjz6f9	255	8	3	3	CD
cord-273487-nfgjz6f9	255	9	containment	containment	NN
cord-273487-nfgjz6f9	255	10	conditions	condition	NNS
cord-273487-nfgjz6f9	255	11	.	.	.
cord-273487-nfgjz6f9	256	1	Unless	unless	IN
cord-273487-nfgjz6f9	256	2	otherwise	otherwise	RB
cord-273487-nfgjz6f9	256	3	indicated	indicate	VBN
cord-273487-nfgjz6f9	256	4	,	,	,
cord-273487-nfgjz6f9	256	5	cultured	cultured	JJ
cord-273487-nfgjz6f9	256	6	cells	cell	NNS
cord-273487-nfgjz6f9	256	7	were	be	VBD
cord-273487-nfgjz6f9	256	8	infected	infect	VBN
cord-273487-nfgjz6f9	256	9	using	use	VBG
cord-273487-nfgjz6f9	256	10	an	an	DT
cord-273487-nfgjz6f9	256	11	MOI	MOI	NNP
cord-273487-nfgjz6f9	256	12	of	of	IN
cord-273487-nfgjz6f9	256	13	5	5	CD
cord-273487-nfgjz6f9	256	14	.	.	.
cord-273487-nfgjz6f9	257	1	Plaque	plaque	NN
cord-273487-nfgjz6f9	257	2	assays	assay	NNS
cord-273487-nfgjz6f9	257	3	were	be	VBD
cord-273487-nfgjz6f9	257	4	conducted	conduct	VBN
cord-273487-nfgjz6f9	257	5	using	use	VBG
cord-273487-nfgjz6f9	257	6	BHK21	BHK21	NNP
cord-273487-nfgjz6f9	257	7	cells	cell	NNS
cord-273487-nfgjz6f9	257	8	as	as	IN
cord-273487-nfgjz6f9	257	9	described	describe	VBN
cord-273487-nfgjz6f9	257	10	(	(	-LRB-
cord-273487-nfgjz6f9	257	11	Xu	Xu	NNP
cord-273487-nfgjz6f9	257	12	et	et	NNP
cord-273487-nfgjz6f9	257	13	al	al	NNP
cord-273487-nfgjz6f9	257	14	.	.	NNP
cord-273487-nfgjz6f9	257	15	,	,	,
cord-273487-nfgjz6f9	257	16	2011	2011	CD
cord-273487-nfgjz6f9	257	17	)	)	-RRB-
cord-273487-nfgjz6f9	257	18	.	.	.
cord-273487-nfgjz6f9	258	1	To	to	TO
cord-273487-nfgjz6f9	258	2	recover	recover	VB
cord-273487-nfgjz6f9	258	3	WNV	WNV	NNP
cord-273487-nfgjz6f9	258	4	particles	particle	NNS
cord-273487-nfgjz6f9	258	5	from	from	IN
cord-273487-nfgjz6f9	258	6	infected	infected	JJ
cord-273487-nfgjz6f9	258	7	cells	cell	NNS
cord-273487-nfgjz6f9	258	8	,	,	,
cord-273487-nfgjz6f9	258	9	medium	medium	NN
cord-273487-nfgjz6f9	258	10	from	from	IN
cord-273487-nfgjz6f9	258	11	infected	infected	JJ
cord-273487-nfgjz6f9	258	12	cells	cell	NNS
cord-273487-nfgjz6f9	258	13	was	be	VBD
cord-273487-nfgjz6f9	258	14	precleared	precleare	VBN
cord-273487-nfgjz6f9	258	15	of	of	IN
cord-273487-nfgjz6f9	258	16	cell	cell	NN
cord-273487-nfgjz6f9	258	17	debris	debris	NN
cord-273487-nfgjz6f9	258	18	by	by	IN
cord-273487-nfgjz6f9	258	19	centrifugation	centrifugation	NN
cord-273487-nfgjz6f9	258	20	for	for	IN
cord-273487-nfgjz6f9	258	21	10	10	CD
cord-273487-nfgjz6f9	258	22	min	min	NN
cord-273487-nfgjz6f9	258	23	at	at	IN
cord-273487-nfgjz6f9	258	24	2500	2500	CD
cord-273487-nfgjz6f9	258	25	Â	â	NN
cord-273487-nfgjz6f9	258	26	g	g	NN
cord-273487-nfgjz6f9	258	27	,	,	,
cord-273487-nfgjz6f9	258	28	after	after	IN
cord-273487-nfgjz6f9	258	29	which	which	WDT
cord-273487-nfgjz6f9	258	30	the	the	DT
cord-273487-nfgjz6f9	258	31	resulting	result	VBG
cord-273487-nfgjz6f9	258	32	supernatants	supernatant	NNS
cord-273487-nfgjz6f9	258	33	were	be	VBD
cord-273487-nfgjz6f9	258	34	passed	pass	VBN
cord-273487-nfgjz6f9	258	35	through	through	IN
cord-273487-nfgjz6f9	258	36	0.45-mm	0.45-mm	CD
cord-273487-nfgjz6f9	258	37	filters	filter	NNS
cord-273487-nfgjz6f9	258	38	.	.	.
cord-273487-nfgjz6f9	259	1	Virus	virus	NN
cord-273487-nfgjz6f9	259	2	was	be	VBD
cord-273487-nfgjz6f9	259	3	inactivated	inactivate	VBN
cord-273487-nfgjz6f9	259	4	by	by	IN
cord-273487-nfgjz6f9	259	5	exposure	exposure	NN
cord-273487-nfgjz6f9	259	6	to	to	IN
cord-273487-nfgjz6f9	259	7	ultraviolet	ultraviolet	JJ
cord-273487-nfgjz6f9	259	8	light	light	NN
cord-273487-nfgjz6f9	259	9	in	in	IN
cord-273487-nfgjz6f9	259	10	a	a	DT
cord-273487-nfgjz6f9	259	11	biosafety	biosafety	NN
cord-273487-nfgjz6f9	259	12	cabinet	cabinet	NN
cord-273487-nfgjz6f9	259	13	for	for	IN
cord-273487-nfgjz6f9	259	14	1	1	CD
cord-273487-nfgjz6f9	259	15	h	h	NN
cord-273487-nfgjz6f9	259	16	prior	prior	RB
cord-273487-nfgjz6f9	259	17	to	to	IN
cord-273487-nfgjz6f9	259	18	removal	removal	NN
cord-273487-nfgjz6f9	259	19	of	of	IN
cord-273487-nfgjz6f9	259	20	the	the	DT
cord-273487-nfgjz6f9	259	21	material	material	NN
cord-273487-nfgjz6f9	259	22	out	out	IN
cord-273487-nfgjz6f9	259	23	of	of	IN
cord-273487-nfgjz6f9	259	24	the	the	DT
cord-273487-nfgjz6f9	259	25	level	level	NN
cord-273487-nfgjz6f9	259	26	3	3	CD
cord-273487-nfgjz6f9	259	27	facility	facility	NN
cord-273487-nfgjz6f9	259	28	.	.	.
cord-273487-nfgjz6f9	260	1	WNV	WNV	NNP
cord-273487-nfgjz6f9	260	2	virions	virion	NNS
cord-273487-nfgjz6f9	260	3	were	be	VBD
cord-273487-nfgjz6f9	260	4	then	then	RB
cord-273487-nfgjz6f9	260	5	recovered	recover	VBN
cord-273487-nfgjz6f9	260	6	from	from	IN
cord-273487-nfgjz6f9	260	7	the	the	DT
cord-273487-nfgjz6f9	260	8	clarified	clarify	VBN
cord-273487-nfgjz6f9	260	9	medium	medium	NN
cord-273487-nfgjz6f9	260	10	by	by	IN
cord-273487-nfgjz6f9	260	11	centrifugation	centrifugation	NN
cord-273487-nfgjz6f9	260	12	at	at	IN
cord-273487-nfgjz6f9	260	13	100,000	100,000	CD
cord-273487-nfgjz6f9	260	14	Â	â	NN
cord-273487-nfgjz6f9	260	15	g	g	NN
cord-273487-nfgjz6f9	260	16	for	for	IN
cord-273487-nfgjz6f9	260	17	1	1	CD
cord-273487-nfgjz6f9	260	18	h.	h.	NNP
cord-273487-nfgjz6f9	260	19	Total	Total	NNP
cord-273487-nfgjz6f9	260	20	RNA	RNA	NNP
cord-273487-nfgjz6f9	260	21	from	from	IN
cord-273487-nfgjz6f9	260	22	crude	crude	JJ
cord-273487-nfgjz6f9	260	23	WNV	WNV	NNP
cord-273487-nfgjz6f9	260	24	virion	virion	NN
cord-273487-nfgjz6f9	260	25	preparations	preparation	NNS
cord-273487-nfgjz6f9	260	26	was	be	VBD
cord-273487-nfgjz6f9	260	27	isolated	isolate	VBN
cord-273487-nfgjz6f9	260	28	with	with	IN
cord-273487-nfgjz6f9	260	29	TRIzol	TRIzol	NNP
cord-273487-nfgjz6f9	260	30	s	s	NNP
cord-273487-nfgjz6f9	260	31	reagent	reagent	NN
cord-273487-nfgjz6f9	260	32	(	(	-LRB-
cord-273487-nfgjz6f9	260	33	Invitrogen	Invitrogen	NNP
cord-273487-nfgjz6f9	260	34	)	)	-RRB-
cord-273487-nfgjz6f9	260	35	according	accord	VBG
cord-273487-nfgjz6f9	260	36	to	to	IN
cord-273487-nfgjz6f9	260	37	the	the	DT
cord-273487-nfgjz6f9	260	38	manufacturer	manufacturer	NN
cord-273487-nfgjz6f9	260	39	's	's	POS
cord-273487-nfgjz6f9	260	40	instructions	instruction	NNS
cord-273487-nfgjz6f9	260	41	.	.	.
cord-273487-nfgjz6f9	261	1	Reverse	reverse	JJ
cord-273487-nfgjz6f9	261	2	transcription	transcription	NN
cord-273487-nfgjz6f9	261	3	and	and	CC
cord-273487-nfgjz6f9	261	4	quantitative	quantitative	JJ
cord-273487-nfgjz6f9	261	5	PCR	PCR	NNP
cord-273487-nfgjz6f9	261	6	analyses	analysis	NNS
cord-273487-nfgjz6f9	261	7	of	of	IN
cord-273487-nfgjz6f9	261	8	WNV	WNV	NNP
cord-273487-nfgjz6f9	261	9	genomic	genomic	JJ
cord-273487-nfgjz6f9	261	10	RNA	RNA	NNP
cord-273487-nfgjz6f9	261	11	was	be	VBD
cord-273487-nfgjz6f9	261	12	performed	perform	VBN
cord-273487-nfgjz6f9	261	13	as	as	IN
cord-273487-nfgjz6f9	261	14	described	describe	VBN
cord-273487-nfgjz6f9	261	15	(	(	-LRB-
cord-273487-nfgjz6f9	261	16	Xu	Xu	NNP
cord-273487-nfgjz6f9	261	17	et	et	NNP
cord-273487-nfgjz6f9	261	18	al	al	NNP
cord-273487-nfgjz6f9	261	19	.	.	NNP
cord-273487-nfgjz6f9	261	20	,	,	,
cord-273487-nfgjz6f9	261	21	2011	2011	CD
cord-273487-nfgjz6f9	261	22	)	)	-RRB-
cord-273487-nfgjz6f9	261	23	.	.	.
cord-273487-nfgjz6f9	262	1	The	the	DT
cord-273487-nfgjz6f9	262	2	relative	relative	JJ
cord-273487-nfgjz6f9	262	3	amount	amount	NN
cord-273487-nfgjz6f9	262	4	of	of	IN
cord-273487-nfgjz6f9	262	5	WNV	WNV	NNP
cord-273487-nfgjz6f9	262	6	genomic	genomic	JJ
cord-273487-nfgjz6f9	262	7	RNA	RNA	NNP
cord-273487-nfgjz6f9	262	8	in	in	IN
cord-273487-nfgjz6f9	262	9	each	each	DT
cord-273487-nfgjz6f9	262	10	sample	sample	NN
cord-273487-nfgjz6f9	262	11	was	be	VBD
cord-273487-nfgjz6f9	262	12	normalized	normalize	VBN
cord-273487-nfgjz6f9	262	13	to	to	IN
cord-273487-nfgjz6f9	262	14	the	the	DT
cord-273487-nfgjz6f9	262	15	amount	amount	NN
cord-273487-nfgjz6f9	262	16	of	of	IN
cord-273487-nfgjz6f9	262	17	capsid	capsid	NN
cord-273487-nfgjz6f9	262	18	protein	protein	NN
cord-273487-nfgjz6f9	262	19	which	which	WDT
cord-273487-nfgjz6f9	262	20	was	be	VBD
cord-273487-nfgjz6f9	262	21	determined	determine	VBN
cord-273487-nfgjz6f9	262	22	by	by	IN
cord-273487-nfgjz6f9	262	23	immunoblotting	immunoblotte	VBG
cord-273487-nfgjz6f9	262	24	.	.	.
cord-273487-nfgjz6f9	263	1	DDX3	DDX3	NNP
cord-273487-nfgjz6f9	263	2	DEAD	DEAD	NNP
cord-273487-nfgjz6f9	263	3	-	-	HYPH
cord-273487-nfgjz6f9	263	4	box	box	NN
cord-273487-nfgjz6f9	263	5	RNA	RNA	NNP
cord-273487-nfgjz6f9	263	6	helicase	helicase	NNP
cord-273487-nfgjz6f9	263	7	is	be	VBZ
cord-273487-nfgjz6f9	263	8	required	require	VBN
cord-273487-nfgjz6f9	263	9	for	for	IN
cord-273487-nfgjz6f9	263	10	hepatitis	hepatitis	NNP
cord-273487-nfgjz6f9	263	11	C	C	NNP
cord-273487-nfgjz6f9	263	12	virus	virus	NN
cord-273487-nfgjz6f9	263	13	RNA	RNA	NNP
cord-273487-nfgjz6f9	263	14	replication	replication	NN
cord-273487-nfgjz6f9	264	1	The	the	DT
cord-273487-nfgjz6f9	264	2	molecular	molecular	JJ
cord-273487-nfgjz6f9	264	3	biology	biology	NN
cord-273487-nfgjz6f9	264	4	of	of	IN
cord-273487-nfgjz6f9	264	5	West	West	NNP
cord-273487-nfgjz6f9	264	6	Nile	Nile	NNP
cord-273487-nfgjz6f9	264	7	virus	virus	NN
cord-273487-nfgjz6f9	264	8	:	:	:
cord-273487-nfgjz6f9	264	9	a	a	DT
cord-273487-nfgjz6f9	264	10	new	new	JJ
cord-273487-nfgjz6f9	264	11	invader	invader	NN
cord-273487-nfgjz6f9	264	12	of	of	IN
cord-273487-nfgjz6f9	264	13	the	the	DT
cord-273487-nfgjz6f9	264	14	western	western	JJ
cord-273487-nfgjz6f9	264	15	hemisphere	hemisphere	NN
cord-273487-nfgjz6f9	265	1	A	a	DT
cord-273487-nfgjz6f9	265	2	DEAD	dead	JJ
cord-273487-nfgjz6f9	265	3	box	box	NN
cord-273487-nfgjz6f9	265	4	protein	protein	NN
cord-273487-nfgjz6f9	265	5	facilitates	facilitate	VBZ
cord-273487-nfgjz6f9	265	6	HIV-1	HIV-1	NNP
cord-273487-nfgjz6f9	265	7	replication	replication	NN
cord-273487-nfgjz6f9	265	8	as	as	IN
cord-273487-nfgjz6f9	265	9	a	a	DT
cord-273487-nfgjz6f9	265	10	cellular	cellular	JJ
cord-273487-nfgjz6f9	265	11	co	co	NN
cord-273487-nfgjz6f9	265	12	-	-	NN
cord-273487-nfgjz6f9	265	13	factor	factor	NN
cord-273487-nfgjz6f9	265	14	of	of	IN
cord-273487-nfgjz6f9	265	15	Rev	Rev	NNP
cord-273487-nfgjz6f9	265	16	Focus	Focus	NNP
cord-273487-nfgjz6f9	265	17	on	on	IN
cord-273487-nfgjz6f9	265	18	flaviviruses	flavivirus	NNS
cord-273487-nfgjz6f9	265	19	:	:	:
cord-273487-nfgjz6f9	265	20	current	current	JJ
cord-273487-nfgjz6f9	265	21	and	and	CC
cord-273487-nfgjz6f9	265	22	future	future	JJ
cord-273487-nfgjz6f9	265	23	drug	drug	NN
cord-273487-nfgjz6f9	265	24	targets	target	NNS
cord-273487-nfgjz6f9	265	25	Interactions	interaction	NNS
cord-273487-nfgjz6f9	265	26	between	between	IN
cord-273487-nfgjz6f9	265	27	the	the	DT
cord-273487-nfgjz6f9	265	28	West	West	NNP
cord-273487-nfgjz6f9	265	29	Nile	Nile	NNP
cord-273487-nfgjz6f9	265	30	virus	virus	NN
cord-273487-nfgjz6f9	265	31	capsid	capsid	NN
cord-273487-nfgjz6f9	265	32	protein	protein	NN
cord-273487-nfgjz6f9	265	33	and	and	CC
cord-273487-nfgjz6f9	265	34	the	the	DT
cord-273487-nfgjz6f9	265	35	host	host	NN
cord-273487-nfgjz6f9	265	36	cell	cell	NN
cord-273487-nfgjz6f9	265	37	-	-	HYPH
cord-273487-nfgjz6f9	265	38	encoded	encode	VBN
cord-273487-nfgjz6f9	265	39	phosphatase	phosphatase	NN
cord-273487-nfgjz6f9	265	40	inhibitor	inhibitor	NN
cord-273487-nfgjz6f9	265	41	RNA	RNA	NNP
cord-273487-nfgjz6f9	265	42	interference	interference	NN
cord-273487-nfgjz6f9	265	43	screen	screen	NN
cord-273487-nfgjz6f9	265	44	for	for	IN
cord-273487-nfgjz6f9	265	45	human	human	JJ
cord-273487-nfgjz6f9	265	46	genes	gene	NNS
cord-273487-nfgjz6f9	265	47	associated	associate	VBN
cord-273487-nfgjz6f9	265	48	with	with	IN
cord-273487-nfgjz6f9	265	49	West	West	NNP
cord-273487-nfgjz6f9	265	50	Nile	Nile	NNP
cord-273487-nfgjz6f9	265	51	virus	virus	NN
cord-273487-nfgjz6f9	265	52	infection	infection	NN
cord-273487-nfgjz6f9	265	53	Viral	viral	JJ
cord-273487-nfgjz6f9	265	54	and	and	CC
cord-273487-nfgjz6f9	265	55	cellular	cellular	JJ
cord-273487-nfgjz6f9	265	56	RNA	RNA	NNP
cord-273487-nfgjz6f9	265	57	helicases	helicase	NNS
cord-273487-nfgjz6f9	265	58	as	as	IN
cord-273487-nfgjz6f9	265	59	antiviral	antiviral	JJ
cord-273487-nfgjz6f9	265	60	targets	target	NNS
cord-273487-nfgjz6f9	265	61	Complementation	Complementation	NNP
cord-273487-nfgjz6f9	265	62	analysis	analysis	NN
cord-273487-nfgjz6f9	265	63	of	of	IN
cord-273487-nfgjz6f9	265	64	the	the	DT
cord-273487-nfgjz6f9	265	65	flavivirus	flavivirus	NNP
cord-273487-nfgjz6f9	265	66	Kunjin	Kunjin	NNP
cord-273487-nfgjz6f9	265	67	NS3	NS3	NNP
cord-273487-nfgjz6f9	265	68	and	and	CC
cord-273487-nfgjz6f9	265	69	NS5	ns5	JJ
cord-273487-nfgjz6f9	265	70	proteins	protein	NNS
cord-273487-nfgjz6f9	265	71	defines	define	VBZ
cord-273487-nfgjz6f9	265	72	the	the	DT
cord-273487-nfgjz6f9	265	73	minimal	minimal	JJ
cord-273487-nfgjz6f9	265	74	regions	region	NNS
cord-273487-nfgjz6f9	265	75	essential	essential	JJ
cord-273487-nfgjz6f9	265	76	for	for	IN
cord-273487-nfgjz6f9	265	77	formation	formation	NN
cord-273487-nfgjz6f9	265	78	of	of	IN
cord-273487-nfgjz6f9	265	79	a	a	DT
cord-273487-nfgjz6f9	265	80	replication	replication	NN
cord-273487-nfgjz6f9	265	81	complex	complex	NN
cord-273487-nfgjz6f9	265	82	and	and	CC
cord-273487-nfgjz6f9	265	83	shows	show	VBZ
cord-273487-nfgjz6f9	265	84	a	a	DT
cord-273487-nfgjz6f9	265	85	requirement	requirement	NN
cord-273487-nfgjz6f9	265	86	of	of	IN
cord-273487-nfgjz6f9	265	87	NS3	ns3	RB
cord-273487-nfgjz6f9	265	88	in	in	IN
cord-273487-nfgjz6f9	265	89	cis	cis	NNP
cord-273487-nfgjz6f9	265	90	for	for	IN
cord-273487-nfgjz6f9	265	91	virus	virus	NNP
cord-273487-nfgjz6f9	265	92	assembly	assembly	NNP
cord-273487-nfgjz6f9	266	1	The	the	DT
cord-273487-nfgjz6f9	266	2	requirement	requirement	NN
cord-273487-nfgjz6f9	266	3	of	of	IN
cord-273487-nfgjz6f9	266	4	the	the	DT
cord-273487-nfgjz6f9	266	5	DEAD	DEAD	NNP
cord-273487-nfgjz6f9	266	6	-	-	HYPH
cord-273487-nfgjz6f9	266	7	box	box	NN
cord-273487-nfgjz6f9	266	8	protein	protein	NN
cord-273487-nfgjz6f9	266	9	DDX24	ddx24	NN
cord-273487-nfgjz6f9	266	10	for	for	IN
cord-273487-nfgjz6f9	266	11	the	the	DT
cord-273487-nfgjz6f9	266	12	packaging	packaging	NN
cord-273487-nfgjz6f9	266	13	of	of	IN
cord-273487-nfgjz6f9	266	14	human	human	JJ
cord-273487-nfgjz6f9	266	15	immunodeficiency	immunodeficiency	NN
cord-273487-nfgjz6f9	266	16	virus	virus	NN
cord-273487-nfgjz6f9	266	17	type	type	NN
cord-273487-nfgjz6f9	266	18	1	1	CD
cord-273487-nfgjz6f9	266	19	RNA	RNA	NNP
cord-273487-nfgjz6f9	266	20	Toward	toward	IN
cord-273487-nfgjz6f9	266	21	the	the	DT
cord-273487-nfgjz6f9	266	22	discovery	discovery	NN
cord-273487-nfgjz6f9	266	23	of	of	IN
cord-273487-nfgjz6f9	266	24	novel	novel	JJ
cord-273487-nfgjz6f9	266	25	anti	anti	JJ
cord-273487-nfgjz6f9	266	26	-	-	JJ
cord-273487-nfgjz6f9	266	27	HIV	hiv	JJ
cord-273487-nfgjz6f9	266	28	drugs	drug	NNS
cord-273487-nfgjz6f9	266	29	.	.	.
cord-273487-nfgjz6f9	267	1	Second	second	JJ
cord-273487-nfgjz6f9	267	2	-	-	HYPH
cord-273487-nfgjz6f9	267	3	generation	generation	NN
cord-273487-nfgjz6f9	267	4	inhibitors	inhibitor	NNS
cord-273487-nfgjz6f9	267	5	of	of	IN
cord-273487-nfgjz6f9	267	6	the	the	DT
cord-273487-nfgjz6f9	267	7	cellular	cellular	JJ
cord-273487-nfgjz6f9	267	8	ATPase	ATPase	NNP
cord-273487-nfgjz6f9	267	9	DDX3	DDX3	NNP
cord-273487-nfgjz6f9	267	10	with	with	IN
cord-273487-nfgjz6f9	267	11	improved	improved	JJ
cord-273487-nfgjz6f9	267	12	anti	anti	JJ
cord-273487-nfgjz6f9	267	13	-	-	JJ
cord-273487-nfgjz6f9	267	14	HIV	hiv	JJ
cord-273487-nfgjz6f9	267	15	activity	activity	NN
cord-273487-nfgjz6f9	267	16	:	:	:
cord-273487-nfgjz6f9	267	17	synthesis	synthesis	NN
cord-273487-nfgjz6f9	267	18	,	,	,
cord-273487-nfgjz6f9	267	19	structure	structure	NN
cord-273487-nfgjz6f9	267	20	-	-	HYPH
cord-273487-nfgjz6f9	267	21	activity	activity	NN
cord-273487-nfgjz6f9	267	22	relationship	relationship	NN
cord-273487-nfgjz6f9	267	23	analysis	analysis	NN
cord-273487-nfgjz6f9	267	24	,	,	,
cord-273487-nfgjz6f9	267	25	cytotoxicity	cytotoxicity	NN
cord-273487-nfgjz6f9	267	26	studies	study	NNS
cord-273487-nfgjz6f9	267	27	,	,	,
cord-273487-nfgjz6f9	267	28	and	and	CC
cord-273487-nfgjz6f9	267	29	target	target	VB
cord-273487-nfgjz6f9	267	30	validation	validation	NN
cord-273487-nfgjz6f9	267	31	Hepatitis	Hepatitis	NNP
cord-273487-nfgjz6f9	267	32	C	C	NNP
cord-273487-nfgjz6f9	267	33	virus	virus	NN
cord-273487-nfgjz6f9	267	34	core	core	NN
cord-273487-nfgjz6f9	267	35	protein	protein	NN
cord-273487-nfgjz6f9	267	36	binds	bind	VBZ
cord-273487-nfgjz6f9	267	37	to	to	IN
cord-273487-nfgjz6f9	267	38	a	a	DT
cord-273487-nfgjz6f9	267	39	DEAD	dead	JJ
cord-273487-nfgjz6f9	267	40	box	box	NN
cord-273487-nfgjz6f9	267	41	RNA	rna	NN
cord-273487-nfgjz6f9	267	42	helicase	helicase	NN
cord-273487-nfgjz6f9	267	43	Hepatitis	Hepatitis	NNP
cord-273487-nfgjz6f9	267	44	C	C	NNP
cord-273487-nfgjz6f9	267	45	virus	virus	NN
cord-273487-nfgjz6f9	267	46	core	core	NN
cord-273487-nfgjz6f9	267	47	protein	protein	NN
cord-273487-nfgjz6f9	267	48	interacts	interact	VBZ
cord-273487-nfgjz6f9	267	49	with	with	IN
cord-273487-nfgjz6f9	267	50	a	a	DT
cord-273487-nfgjz6f9	267	51	human	human	JJ
cord-273487-nfgjz6f9	267	52	DEAD	DEAD	NNP
cord-273487-nfgjz6f9	267	53	box	box	NN
cord-273487-nfgjz6f9	267	54	protein	protein	NN
cord-273487-nfgjz6f9	267	55	DDX3	DDX3	NNP
cord-273487-nfgjz6f9	267	56	Yellow	Yellow	NNP
cord-273487-nfgjz6f9	267	57	Fever	Fever	NNP
cord-273487-nfgjz6f9	267	58	virus	virus	NN
cord-273487-nfgjz6f9	268	1	NS3	ns3	RB
cord-273487-nfgjz6f9	268	2	plays	play	VBZ
cord-273487-nfgjz6f9	268	3	an	an	DT
cord-273487-nfgjz6f9	268	4	essential	essential	JJ
cord-273487-nfgjz6f9	268	5	role	role	NN
cord-273487-nfgjz6f9	268	6	in	in	IN
cord-273487-nfgjz6f9	268	7	virus	virus	NN
cord-273487-nfgjz6f9	268	8	assembly	assembly	NN
cord-273487-nfgjz6f9	268	9	independent	independent	JJ
cord-273487-nfgjz6f9	268	10	of	of	IN
cord-273487-nfgjz6f9	268	11	its	-PRON-	PRP$
cord-273487-nfgjz6f9	268	12	known	know	VBN
cord-273487-nfgjz6f9	268	13	enzymatic	enzymatic	JJ
cord-273487-nfgjz6f9	268	14	functions	function	NNS
cord-273487-nfgjz6f9	269	1	Mutational	mutational	JJ
cord-273487-nfgjz6f9	269	2	analysis	analysis	NN
cord-273487-nfgjz6f9	269	3	of	of	IN
cord-273487-nfgjz6f9	269	4	a	a	DT
cord-273487-nfgjz6f9	269	5	DEAD	DEAD	NNP
cord-273487-nfgjz6f9	269	6	box	box	NN
cord-273487-nfgjz6f9	269	7	RNA	RNA	NNP
cord-273487-nfgjz6f9	269	8	helicase	helicase	NNP
cord-273487-nfgjz6f9	269	9	:	:	:
cord-273487-nfgjz6f9	269	10	the	the	DT
cord-273487-nfgjz6f9	269	11	mammalian	mammalian	JJ
cord-273487-nfgjz6f9	269	12	translation	translation	NN
cord-273487-nfgjz6f9	269	13	initiation	initiation	NN
cord-273487-nfgjz6f9	269	14	factor	factor	NN
cord-273487-nfgjz6f9	269	15	eIF-4A	eif-4a	XX
cord-273487-nfgjz6f9	269	16	D	D	NNP
cord-273487-nfgjz6f9	269	17	-	-	HYPH
cord-273487-nfgjz6f9	269	18	E	e	NN
cord-273487-nfgjz6f9	269	19	-	-	HYPH
cord-273487-nfgjz6f9	269	20	A	a	NN
cord-273487-nfgjz6f9	269	21	-	-	HYPH
cord-273487-nfgjz6f9	269	22	D	d	NN
cord-273487-nfgjz6f9	269	23	protein	protein	NN
cord-273487-nfgjz6f9	269	24	family	family	NN
cord-273487-nfgjz6f9	269	25	of	of	IN
cord-273487-nfgjz6f9	269	26	putative	putative	JJ
cord-273487-nfgjz6f9	269	27	RNA	RNA	NNP
cord-273487-nfgjz6f9	269	28	helicases	helicase	NNS
cord-273487-nfgjz6f9	269	29	Synthesis	Synthesis	NNP
cord-273487-nfgjz6f9	269	30	of	of	IN
cord-273487-nfgjz6f9	269	31	new	new	JJ
cord-273487-nfgjz6f9	269	32	acridone	acridone	NNP
cord-273487-nfgjz6f9	269	33	derivatives	derivative	NNS
cord-273487-nfgjz6f9	269	34	,	,	,
cord-273487-nfgjz6f9	269	35	inhibitors	inhibitor	NNS
cord-273487-nfgjz6f9	269	36	of	of	IN
cord-273487-nfgjz6f9	269	37	NS3	NS3	NNP
cord-273487-nfgjz6f9	269	38	helicase	helicase	NNP
cord-273487-nfgjz6f9	269	39	,	,	,
cord-273487-nfgjz6f9	269	40	which	which	WDT
cord-273487-nfgjz6f9	269	41	efficiently	efficiently	RB
cord-273487-nfgjz6f9	269	42	and	and	CC
cord-273487-nfgjz6f9	269	43	specifically	specifically	RB
cord-273487-nfgjz6f9	269	44	inhibit	inhibit	VB
cord-273487-nfgjz6f9	269	45	subgenomic	subgenomic	JJ
cord-273487-nfgjz6f9	269	46	HCV	HCV	NNP
cord-273487-nfgjz6f9	269	47	replication	replication	NN
cord-273487-nfgjz6f9	269	48	West	West	NNP
cord-273487-nfgjz6f9	269	49	Nile	Nile	NNP
cord-273487-nfgjz6f9	269	50	virus	virus	NN
cord-273487-nfgjz6f9	269	51	-	-	HYPH
cord-273487-nfgjz6f9	269	52	induced	induce	VBN
cord-273487-nfgjz6f9	269	53	neuroinflammation	neuroinflammation	NN
cord-273487-nfgjz6f9	269	54	:	:	:
cord-273487-nfgjz6f9	270	1	glial	glial	JJ
cord-273487-nfgjz6f9	270	2	infection	infection	NN
cord-273487-nfgjz6f9	270	3	and	and	CC
cord-273487-nfgjz6f9	270	4	capsid	capsid	NN
cord-273487-nfgjz6f9	270	5	proteinmediated	proteinmediate	VBN
cord-273487-nfgjz6f9	270	6	neurovirulence	neurovirulence	NNP
cord-273487-nfgjz6f9	271	1	The	the	DT
cord-273487-nfgjz6f9	271	2	cellular	cellular	JJ
cord-273487-nfgjz6f9	271	3	RNA	rna	NN
cord-273487-nfgjz6f9	271	4	helicase	helicase	NN
cord-273487-nfgjz6f9	271	5	DDX1	DDX1	NNP
cord-273487-nfgjz6f9	271	6	interacts	interact	VBZ
cord-273487-nfgjz6f9	271	7	with	with	IN
cord-273487-nfgjz6f9	271	8	coronavirus	coronavirus	NN
cord-273487-nfgjz6f9	271	9	nonstructural	nonstructural	JJ
cord-273487-nfgjz6f9	271	10	protein	protein	NN
cord-273487-nfgjz6f9	271	11	14	14	CD
cord-273487-nfgjz6f9	271	12	and	and	CC
cord-273487-nfgjz6f9	271	13	enhances	enhance	VBZ
cord-273487-nfgjz6f9	271	14	viral	viral	JJ
cord-273487-nfgjz6f9	271	15	replication	replication	NN
cord-273487-nfgjz6f9	272	1	The	the	DT
cord-273487-nfgjz6f9	272	2	capsid	capsid	RB
cord-273487-nfgjz6f9	272	3	-	-	HYPH
cord-273487-nfgjz6f9	272	4	binding	bind	VBG
cord-273487-nfgjz6f9	272	5	nucleolar	nucleolar	NN
cord-273487-nfgjz6f9	272	6	helicase	helicase	NNP
cord-273487-nfgjz6f9	272	7	DDX56	DDX56	NNP
cord-273487-nfgjz6f9	272	8	is	be	VBZ
cord-273487-nfgjz6f9	272	9	important	important	JJ
cord-273487-nfgjz6f9	272	10	for	for	IN
cord-273487-nfgjz6f9	272	11	infectivity	infectivity	NN
cord-273487-nfgjz6f9	272	12	of	of	IN
cord-273487-nfgjz6f9	272	13	West	West	NNP
cord-273487-nfgjz6f9	272	14	Nile	Nile	NNP
cord-273487-nfgjz6f9	272	15	virus	virus	NN
cord-273487-nfgjz6f9	272	16	West	West	NNP
cord-273487-nfgjz6f9	272	17	Nile	Nile	NNP
cord-273487-nfgjz6f9	272	18	virus	virus	NN
cord-273487-nfgjz6f9	272	19	infection	infection	NN
cord-273487-nfgjz6f9	272	20	causes	cause	VBZ
cord-273487-nfgjz6f9	272	21	endocytosis	endocytosis	NN
cord-273487-nfgjz6f9	272	22	of	of	IN
cord-273487-nfgjz6f9	272	23	a	a	DT
cord-273487-nfgjz6f9	272	24	specific	specific	JJ
cord-273487-nfgjz6f9	272	25	subset	subset	NN
cord-273487-nfgjz6f9	272	26	of	of	IN
cord-273487-nfgjz6f9	272	27	tight	tight	JJ
cord-273487-nfgjz6f9	272	28	junction	junction	NN
cord-273487-nfgjz6f9	272	29	membrane	membrane	NN
cord-273487-nfgjz6f9	272	30	proteins	protein	NNS
cord-273487-nfgjz6f9	272	31	Requirement	Requirement	NNP
cord-273487-nfgjz6f9	272	32	of	of	IN
cord-273487-nfgjz6f9	272	33	DDX3	DDX3	NNP
cord-273487-nfgjz6f9	272	34	DEAD	DEAD	NNP
cord-273487-nfgjz6f9	272	35	box	box	NN
cord-273487-nfgjz6f9	272	36	RNA	RNA	NNP
cord-273487-nfgjz6f9	272	37	helicase	helicase	NN
cord-273487-nfgjz6f9	272	38	for	for	IN
cord-273487-nfgjz6f9	272	39	HIV-1	HIV-1	NNP
cord-273487-nfgjz6f9	272	40	Rev	Rev	NNP
cord-273487-nfgjz6f9	272	41	-	-	HYPH
cord-273487-nfgjz6f9	272	42	RRE	RRE	NNP
cord-273487-nfgjz6f9	272	43	export	export	NN
cord-273487-nfgjz6f9	272	44	function	function	NN
cord-273487-nfgjz6f9	273	1	Hepatitis	Hepatitis	NNP
cord-273487-nfgjz6f9	273	2	C	C	NNP
cord-273487-nfgjz6f9	273	3	virus	virus	NN
cord-273487-nfgjz6f9	273	4	core	core	NN
cord-273487-nfgjz6f9	273	5	protein	protein	NN
cord-273487-nfgjz6f9	273	6	enhances	enhance	VBZ
cord-273487-nfgjz6f9	273	7	NF	NF	NNP
cord-273487-nfgjz6f9	273	8	-	-	HYPH
cord-273487-nfgjz6f9	273	9	kappaB	kappaB	NNP
cord-273487-nfgjz6f9	273	10	signal	signal	NN
cord-273487-nfgjz6f9	273	11	pathway	pathway	NN
cord-273487-nfgjz6f9	273	12	triggering	trigger	VBG
cord-273487-nfgjz6f9	273	13	by	by	IN
cord-273487-nfgjz6f9	273	14	lymphotoxin	lymphotoxin	NN
cord-273487-nfgjz6f9	273	15	-	-	HYPH
cord-273487-nfgjz6f9	273	16	beta	beta	NN
cord-273487-nfgjz6f9	273	17	receptor	receptor	NN
cord-273487-nfgjz6f9	273	18	ligand	ligand	NN
cord-273487-nfgjz6f9	273	19	and	and	CC
cord-273487-nfgjz6f9	273	20	tumor	tumor	NN
cord-273487-nfgjz6f9	273	21	necrosis	necrosis	NN
cord-273487-nfgjz6f9	273	22	factor	factor	NN
cord-273487-nfgjz6f9	274	1	alpha	alpha	NNP
cord-273487-nfgjz6f9	274	2	A	a	DT
cord-273487-nfgjz6f9	274	3	novel	novel	JJ
cord-273487-nfgjz6f9	274	4	helicasetype	helicasetype	NN
cord-273487-nfgjz6f9	274	5	protein	protein	NN
cord-273487-nfgjz6f9	274	6	in	in	IN
cord-273487-nfgjz6f9	274	7	the	the	DT
cord-273487-nfgjz6f9	274	8	nucleolus	nucleolus	NN
cord-273487-nfgjz6f9	274	9	:	:	:
cord-273487-nfgjz6f9	275	1	protein	protein	NNP
cord-273487-nfgjz6f9	276	1	NOH61	noh61	UH
cord-273487-nfgjz6f9	277	1	We	-PRON-	PRP
cord-273487-nfgjz6f9	277	2	thank	thank	VBP
cord-273487-nfgjz6f9	277	3	Eileen	Eileen	NNP
cord-273487-nfgjz6f9	277	4	Reklow	Reklow	NNP
cord-273487-nfgjz6f9	277	5	and	and	CC
cord-273487-nfgjz6f9	277	6	Valeria	Valeria	NNP
cord-273487-nfgjz6f9	277	7	Mancinelli	Mancinelli	NNP
cord-273487-nfgjz6f9	277	8	for	for	IN
cord-273487-nfgjz6f9	277	9	technical	technical	JJ
cord-273487-nfgjz6f9	277	10	support	support	NN
cord-273487-nfgjz6f9	277	11	.	.	.
cord-273487-nfgjz6f9	278	1	Z.X.	Z.X.	NNP
cord-273487-nfgjz6f9	278	2	is	be	VBZ
cord-273487-nfgjz6f9	278	3	the	the	DT
cord-273487-nfgjz6f9	278	4	recipient	recipient	NN
cord-273487-nfgjz6f9	278	5	of	of	IN
cord-273487-nfgjz6f9	278	6	a	a	DT
cord-273487-nfgjz6f9	278	7	graduate	graduate	NN
cord-273487-nfgjz6f9	278	8	studentship	studentship	NN
cord-273487-nfgjz6f9	278	9	award	award	NN
cord-273487-nfgjz6f9	278	10	from	from	IN
cord-273487-nfgjz6f9	278	11	Alberta	Alberta	NNP
cord-273487-nfgjz6f9	278	12	Innovates	innovate	VBZ
cord-273487-nfgjz6f9	278	13	Health	Health	NNP
cord-273487-nfgjz6f9	278	14	Solutions	Solutions	NNPS
cord-273487-nfgjz6f9	278	15	(	(	-LRB-
cord-273487-nfgjz6f9	278	16	AIHS	AIHS	NNP
cord-273487-nfgjz6f9	278	17	)	)	-RRB-
cord-273487-nfgjz6f9	278	18	.	.	.
cord-273487-nfgjz6f9	279	1	T.C.H.	T.C.H.	NNP
cord-273487-nfgjz6f9	279	2	holds	hold	VBZ
cord-273487-nfgjz6f9	279	3	a	a	DT
cord-273487-nfgjz6f9	279	4	Scientist	Scientist	NNP
cord-273487-nfgjz6f9	279	5	award	award	NN
cord-273487-nfgjz6f9	279	6	from	from	IN
cord-273487-nfgjz6f9	279	7	AIHS	AIHS	NNP
cord-273487-nfgjz6f9	279	8	and	and	CC
cord-273487-nfgjz6f9	279	9	is	be	VBZ
cord-273487-nfgjz6f9	279	10	a	a	DT
cord-273487-nfgjz6f9	279	11	Canada	Canada	NNP
cord-273487-nfgjz6f9	279	12	Research	Research	NNP
cord-273487-nfgjz6f9	279	13	Chair	Chair	NNP
cord-273487-nfgjz6f9	279	14	.	.	.
cord-273487-nfgjz6f9	280	1	This	this	DT
cord-273487-nfgjz6f9	280	2	work	work	NN
cord-273487-nfgjz6f9	280	3	was	be	VBD
cord-273487-nfgjz6f9	280	4	supported	support	VBN
cord-273487-nfgjz6f9	280	5	by	by	IN
cord-273487-nfgjz6f9	280	6	operating	operate	VBG
cord-273487-nfgjz6f9	280	7	funds	fund	NNS
cord-273487-nfgjz6f9	280	8	from	from	IN
cord-273487-nfgjz6f9	280	9	the	the	DT
cord-273487-nfgjz6f9	280	10	Canadian	Canadian	NNP
cord-273487-nfgjz6f9	280	11	Institutes	Institutes	NNPS
cord-273487-nfgjz6f9	280	12	of	of	IN
cord-273487-nfgjz6f9	280	13	Health	Health	NNP
cord-273487-nfgjz6f9	280	14	Research	Research	NNP
cord-273487-nfgjz6f9	280	15	.	.	.