id	sid	tid	token	lemma	pos
cord-322904-9mta0aem	1	1	key	key	NN
cord-322904-9mta0aem	1	2	:	:	:
cord-322904-9mta0aem	2	1	cord-322904	cord-322904	NNP
cord-322904-9mta0aem	2	2	-	-	:
cord-322904-9mta0aem	2	3	9mta0aem	9mta0aem	CD
cord-322904-9mta0aem	2	4	authors	author	NNS
cord-322904-9mta0aem	2	5	:	:	:
cord-322904-9mta0aem	2	6	Neu	Neu	NNP
cord-322904-9mta0aem	2	7	,	,	,
cord-322904-9mta0aem	2	8	Ursula	Ursula	NNP
cord-322904-9mta0aem	2	9	;	;	:
cord-322904-9mta0aem	2	10	Stehle	Stehle	NNP
cord-322904-9mta0aem	2	11	,	,	,
cord-322904-9mta0aem	2	12	Thilo	Thilo	NNP
cord-322904-9mta0aem	2	13	;	;	:
cord-322904-9mta0aem	2	14	Atwood	Atwood	NNP
cord-322904-9mta0aem	2	15	,	,	,
cord-322904-9mta0aem	2	16	Walter	Walter	NNP
cord-322904-9mta0aem	2	17	J.	J.	NNP
cord-322904-9mta0aem	3	1	title	title	NN
cord-322904-9mta0aem	3	2	:	:	:
cord-322904-9mta0aem	4	1	The	the	DT
cord-322904-9mta0aem	4	2	Polyomaviridae	Polyomaviridae	NNP
cord-322904-9mta0aem	4	3	:	:	:
cord-322904-9mta0aem	4	4	Contributions	contribution	NNS
cord-322904-9mta0aem	4	5	of	of	IN
cord-322904-9mta0aem	4	6	virus	virus	NN
cord-322904-9mta0aem	4	7	structure	structure	NN
cord-322904-9mta0aem	4	8	to	to	IN
cord-322904-9mta0aem	4	9	our	-PRON-	PRP$
cord-322904-9mta0aem	4	10	understanding	understanding	NN
cord-322904-9mta0aem	4	11	of	of	IN
cord-322904-9mta0aem	4	12	virus	virus	NN
cord-322904-9mta0aem	4	13	receptors	receptor	NNS
cord-322904-9mta0aem	4	14	and	and	CC
cord-322904-9mta0aem	4	15	infectious	infectious	JJ
cord-322904-9mta0aem	4	16	entry	entry	NN
cord-322904-9mta0aem	4	17	date	date	NN
cord-322904-9mta0aem	4	18	:	:	:
cord-322904-9mta0aem	4	19	2009	2009	CD
cord-322904-9mta0aem	4	20	-	-	SYM
cord-322904-9mta0aem	4	21	02	02	CD
cord-322904-9mta0aem	4	22	-	-	HYPH
cord-322904-9mta0aem	4	23	01	01	CD
cord-322904-9mta0aem	4	24	journal	journal	NN
cord-322904-9mta0aem	4	25	:	:	:
cord-322904-9mta0aem	5	1	Virology	virology	NN
cord-322904-9mta0aem	5	2	DOI	DOI	NNP
cord-322904-9mta0aem	5	3	:	:	:
cord-322904-9mta0aem	5	4	10.1016/	10.1016/	CD
cord-322904-9mta0aem	6	1	j.virol.2008.12.021	j.virol.2008.12.021	NNP
cord-322904-9mta0aem	6	2	sha	sha	NNP
cord-322904-9mta0aem	6	3	:	:	:
cord-322904-9mta0aem	7	1	d935444a4e3a8af17406c536e5483e63a95bafd3	d935444a4e3a8af17406c536e5483e63a95bafd3	NNP
cord-322904-9mta0aem	7	2	doc_id	doc_id	CD
cord-322904-9mta0aem	7	3	:	:	:
cord-322904-9mta0aem	8	1	322904	322904	CD
cord-322904-9mta0aem	8	2	cord_uid	cord_uid	NN
cord-322904-9mta0aem	8	3	:	:	:
cord-322904-9mta0aem	8	4	9mta0aem	9mta0aem	CD
cord-322904-9mta0aem	9	1	This	this	DT
cord-322904-9mta0aem	9	2	review	review	NN
cord-322904-9mta0aem	9	3	summarizes	summarize	VBZ
cord-322904-9mta0aem	9	4	the	the	DT
cord-322904-9mta0aem	9	5	fields	field	NNS
cord-322904-9mta0aem	9	6	major	major	JJ
cord-322904-9mta0aem	9	7	findings	finding	NNS
cord-322904-9mta0aem	9	8	related	relate	VBN
cord-322904-9mta0aem	9	9	to	to	IN
cord-322904-9mta0aem	9	10	the	the	DT
cord-322904-9mta0aem	9	11	characterization	characterization	NN
cord-322904-9mta0aem	9	12	of	of	IN
cord-322904-9mta0aem	9	13	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	9	14	structures	structure	NNS
cord-322904-9mta0aem	9	15	and	and	CC
cord-322904-9mta0aem	9	16	to	to	IN
cord-322904-9mta0aem	9	17	the	the	DT
cord-322904-9mta0aem	9	18	characterization	characterization	NN
cord-322904-9mta0aem	9	19	of	of	IN
cord-322904-9mta0aem	9	20	virus	virus	NN
cord-322904-9mta0aem	9	21	receptors	receptor	NNS
cord-322904-9mta0aem	9	22	and	and	CC
cord-322904-9mta0aem	9	23	mechanisms	mechanism	NNS
cord-322904-9mta0aem	9	24	of	of	IN
cord-322904-9mta0aem	9	25	host	host	NN
cord-322904-9mta0aem	9	26	cell	cell	NN
cord-322904-9mta0aem	9	27	invasion	invasion	NN
cord-322904-9mta0aem	9	28	.	.	.
cord-322904-9mta0aem	10	1	Four	four	CD
cord-322904-9mta0aem	10	2	members	member	NNS
cord-322904-9mta0aem	10	3	of	of	IN
cord-322904-9mta0aem	10	4	the	the	DT
cord-322904-9mta0aem	10	5	family	family	NN
cord-322904-9mta0aem	10	6	that	that	WDT
cord-322904-9mta0aem	10	7	have	have	VBP
cord-322904-9mta0aem	10	8	received	receive	VBN
cord-322904-9mta0aem	10	9	the	the	DT
cord-322904-9mta0aem	10	10	most	most	JJS
cord-322904-9mta0aem	10	11	attention	attention	NN
cord-322904-9mta0aem	10	12	in	in	IN
cord-322904-9mta0aem	10	13	this	this	DT
cord-322904-9mta0aem	10	14	regard	regard	NN
cord-322904-9mta0aem	10	15	are	be	VBP
cord-322904-9mta0aem	10	16	the	the	DT
cord-322904-9mta0aem	10	17	mouse	mouse	NN
cord-322904-9mta0aem	10	18	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	10	19	(	(	-LRB-
cord-322904-9mta0aem	10	20	mPyV	mPyV	NNP
cord-322904-9mta0aem	10	21	)	)	-RRB-
cord-322904-9mta0aem	10	22	,	,	,
cord-322904-9mta0aem	10	23	the	the	DT
cord-322904-9mta0aem	10	24	monkey	monkey	NN
cord-322904-9mta0aem	10	25	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	10	26	SV40	SV40	NNP
cord-322904-9mta0aem	10	27	,	,	,
cord-322904-9mta0aem	10	28	and	and	CC
cord-322904-9mta0aem	10	29	the	the	DT
cord-322904-9mta0aem	10	30	two	two	CD
cord-322904-9mta0aem	10	31	human	human	JJ
cord-322904-9mta0aem	10	32	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	10	33	,	,	,
cord-322904-9mta0aem	10	34	JCV	JCV	NNP
cord-322904-9mta0aem	10	35	and	and	CC
cord-322904-9mta0aem	10	36	BKV	BKV	NNP
cord-322904-9mta0aem	10	37	.	.	.
cord-322904-9mta0aem	11	1	The	the	DT
cord-322904-9mta0aem	11	2	structures	structure	NNS
cord-322904-9mta0aem	11	3	of	of	IN
cord-322904-9mta0aem	11	4	both	both	CC
cord-322904-9mta0aem	11	5	the	the	DT
cord-322904-9mta0aem	11	6	mPyV	mPyV	NNP
cord-322904-9mta0aem	11	7	and	and	CC
cord-322904-9mta0aem	11	8	SV40	SV40	NNP
cord-322904-9mta0aem	11	9	alone	alone	RB
cord-322904-9mta0aem	11	10	and	and	CC
cord-322904-9mta0aem	11	11	in	in	IN
cord-322904-9mta0aem	11	12	complex	complex	NN
cord-322904-9mta0aem	11	13	with	with	IN
cord-322904-9mta0aem	11	14	receptor	receptor	NN
cord-322904-9mta0aem	11	15	fragments	fragment	NNS
cord-322904-9mta0aem	11	16	have	have	VBP
cord-322904-9mta0aem	11	17	been	be	VBN
cord-322904-9mta0aem	11	18	solved	solve	VBN
cord-322904-9mta0aem	11	19	to	to	IN
cord-322904-9mta0aem	11	20	high	high	JJ
cord-322904-9mta0aem	11	21	resolution	resolution	NN
cord-322904-9mta0aem	11	22	.	.	.
cord-322904-9mta0aem	12	1	The	the	DT
cord-322904-9mta0aem	12	2	majority	majority	NN
cord-322904-9mta0aem	12	3	of	of	IN
cord-322904-9mta0aem	12	4	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	12	5	recognize	recognize	VBP
cord-322904-9mta0aem	12	6	terminal	terminal	JJ
cord-322904-9mta0aem	12	7	sialic	sialic	NN
cord-322904-9mta0aem	12	8	acid	acid	NN
cord-322904-9mta0aem	12	9	in	in	IN
cord-322904-9mta0aem	12	10	either	either	CC
cord-322904-9mta0aem	12	11	an	an	DT
cord-322904-9mta0aem	12	12	α	α	NN
cord-322904-9mta0aem	12	13	2,3	2,3	CD
cord-322904-9mta0aem	12	14	linkage	linkage	NN
cord-322904-9mta0aem	12	15	or	or	CC
cord-322904-9mta0aem	12	16	an	an	DT
cord-322904-9mta0aem	12	17	α	α	NN
cord-322904-9mta0aem	12	18	2,6	2,6	CD
cord-322904-9mta0aem	12	19	linkage	linkage	NN
cord-322904-9mta0aem	12	20	to	to	IN
cord-322904-9mta0aem	12	21	the	the	DT
cord-322904-9mta0aem	12	22	underlying	underlying	JJ
cord-322904-9mta0aem	12	23	galactose	galactose	NN
cord-322904-9mta0aem	12	24	.	.	.
cord-322904-9mta0aem	13	1	Studies	study	NNS
cord-322904-9mta0aem	13	2	on	on	IN
cord-322904-9mta0aem	13	3	virus	virus	NN
cord-322904-9mta0aem	13	4	structure	structure	NN
cord-322904-9mta0aem	13	5	,	,	,
cord-322904-9mta0aem	13	6	receptor	receptor	NN
cord-322904-9mta0aem	13	7	utilization	utilization	NN
cord-322904-9mta0aem	13	8	and	and	CC
cord-322904-9mta0aem	13	9	mechanisms	mechanism	NNS
cord-322904-9mta0aem	13	10	of	of	IN
cord-322904-9mta0aem	13	11	entry	entry	NN
cord-322904-9mta0aem	13	12	have	have	VBP
cord-322904-9mta0aem	13	13	led	lead	VBN
cord-322904-9mta0aem	13	14	to	to	IN
cord-322904-9mta0aem	13	15	new	new	JJ
cord-322904-9mta0aem	13	16	insights	insight	NNS
cord-322904-9mta0aem	13	17	into	into	IN
cord-322904-9mta0aem	13	18	how	how	WRB
cord-322904-9mta0aem	13	19	these	these	DT
cord-322904-9mta0aem	13	20	viruses	virus	NNS
cord-322904-9mta0aem	13	21	interact	interact	VBP
cord-322904-9mta0aem	13	22	in	in	IN
cord-322904-9mta0aem	13	23	an	an	DT
cord-322904-9mta0aem	13	24	active	active	JJ
cord-322904-9mta0aem	13	25	way	way	NN
cord-322904-9mta0aem	13	26	with	with	IN
cord-322904-9mta0aem	13	27	cells	cell	NNS
cord-322904-9mta0aem	13	28	to	to	TO
cord-322904-9mta0aem	13	29	ensure	ensure	VB
cord-322904-9mta0aem	13	30	the	the	DT
cord-322904-9mta0aem	13	31	nuclear	nuclear	JJ
cord-322904-9mta0aem	13	32	delivery	delivery	NN
cord-322904-9mta0aem	13	33	and	and	CC
cord-322904-9mta0aem	13	34	expression	expression	NN
cord-322904-9mta0aem	13	35	of	of	IN
cord-322904-9mta0aem	13	36	their	-PRON-	PRP$
cord-322904-9mta0aem	13	37	genomes	genome	NNS
cord-322904-9mta0aem	13	38	.	.	.
cord-322904-9mta0aem	14	1	Critical	critical	JJ
cord-322904-9mta0aem	14	2	work	work	NN
cord-322904-9mta0aem	14	3	on	on	IN
cord-322904-9mta0aem	14	4	virus	virus	NN
cord-322904-9mta0aem	14	5	entry	entry	NN
cord-322904-9mta0aem	14	6	has	have	VBZ
cord-322904-9mta0aem	14	7	led	lead	VBN
cord-322904-9mta0aem	14	8	to	to	IN
cord-322904-9mta0aem	14	9	the	the	DT
cord-322904-9mta0aem	14	10	discovery	discovery	NN
cord-322904-9mta0aem	14	11	of	of	IN
cord-322904-9mta0aem	14	12	a	a	DT
cord-322904-9mta0aem	14	13	pH	pH	NNP
cord-322904-9mta0aem	14	14	neutral	neutral	JJ
cord-322904-9mta0aem	14	15	endocytic	endocytic	JJ
cord-322904-9mta0aem	14	16	compartment	compartment	NN
cord-322904-9mta0aem	14	17	that	that	WDT
cord-322904-9mta0aem	14	18	accepts	accept	VBZ
cord-322904-9mta0aem	14	19	cargo	cargo	NN
cord-322904-9mta0aem	14	20	from	from	IN
cord-322904-9mta0aem	14	21	caveolae	caveolae	NNP
cord-322904-9mta0aem	14	22	and	and	CC
cord-322904-9mta0aem	14	23	to	to	IN
cord-322904-9mta0aem	14	24	novel	novel	JJ
cord-322904-9mta0aem	14	25	roles	role	NNS
cord-322904-9mta0aem	14	26	for	for	IN
cord-322904-9mta0aem	14	27	endoplasmic	endoplasmic	NN
cord-322904-9mta0aem	14	28	reticulum	reticulum	NN
cord-322904-9mta0aem	14	29	(	(	-LRB-
cord-322904-9mta0aem	14	30	ER	ER	NNP
cord-322904-9mta0aem	14	31	)	)	-RRB-
cord-322904-9mta0aem	14	32	associated	associate	VBD
cord-322904-9mta0aem	14	33	factors	factor	NNS
cord-322904-9mta0aem	14	34	in	in	IN
cord-322904-9mta0aem	14	35	virus	virus	NN
cord-322904-9mta0aem	14	36	uncoating	uncoating	NN
cord-322904-9mta0aem	14	37	and	and	CC
cord-322904-9mta0aem	14	38	penetration	penetration	NN
cord-322904-9mta0aem	14	39	of	of	IN
cord-322904-9mta0aem	14	40	ER	ER	NNP
cord-322904-9mta0aem	14	41	membranes	membrane	NNS
cord-322904-9mta0aem	14	42	.	.	.
cord-322904-9mta0aem	15	1	This	this	DT
cord-322904-9mta0aem	15	2	review	review	NN
cord-322904-9mta0aem	15	3	will	will	MD
cord-322904-9mta0aem	15	4	summarize	summarize	VB
cord-322904-9mta0aem	15	5	the	the	DT
cord-322904-9mta0aem	15	6	major	major	JJ
cord-322904-9mta0aem	15	7	findings	finding	NNS
cord-322904-9mta0aem	15	8	and	and	CC
cord-322904-9mta0aem	15	9	compare	compare	VB
cord-322904-9mta0aem	15	10	and	and	CC
cord-322904-9mta0aem	15	11	contrast	contrast	VB
cord-322904-9mta0aem	15	12	the	the	DT
cord-322904-9mta0aem	15	13	mechanisms	mechanism	NNS
cord-322904-9mta0aem	15	14	used	use	VBN
cord-322904-9mta0aem	15	15	by	by	IN
cord-322904-9mta0aem	15	16	these	these	DT
cord-322904-9mta0aem	15	17	viruses	virus	NNS
cord-322904-9mta0aem	15	18	to	to	TO
cord-322904-9mta0aem	15	19	infect	infect	VB
cord-322904-9mta0aem	15	20	cells	cell	NNS
cord-322904-9mta0aem	15	21	.	.	.
cord-322904-9mta0aem	16	1	The	the	DT
cord-322904-9mta0aem	16	2	family	family	NN
cord-322904-9mta0aem	16	3	Polyomaviridae	Polyomaviridae	NNP
cord-322904-9mta0aem	16	4	are	be	VBP
cord-322904-9mta0aem	16	5	classified	classify	VBN
cord-322904-9mta0aem	16	6	as	as	IN
cord-322904-9mta0aem	16	7	group	group	NN
cord-322904-9mta0aem	16	8	1	1	CD
cord-322904-9mta0aem	16	9	viruses	virus	NNS
cord-322904-9mta0aem	16	10	in	in	IN
cord-322904-9mta0aem	16	11	the	the	DT
cord-322904-9mta0aem	16	12	Baltimore	Baltimore	NNP
cord-322904-9mta0aem	16	13	classification	classification	NN
cord-322904-9mta0aem	16	14	scheme	scheme	NN
cord-322904-9mta0aem	16	15	as	as	IN
cord-322904-9mta0aem	16	16	they	-PRON-	PRP
cord-322904-9mta0aem	16	17	contain	contain	VBP
cord-322904-9mta0aem	16	18	double	double	RB
cord-322904-9mta0aem	16	19	stranded	strand	VBN
cord-322904-9mta0aem	16	20	DNA	dna	NN
cord-322904-9mta0aem	16	21	genomes	genome	NNS
cord-322904-9mta0aem	16	22	.	.	.
cord-322904-9mta0aem	17	1	There	there	EX
cord-322904-9mta0aem	17	2	is	be	VBZ
cord-322904-9mta0aem	17	3	a	a	DT
cord-322904-9mta0aem	17	4	single	single	JJ
cord-322904-9mta0aem	17	5	genus	genus	NN
cord-322904-9mta0aem	17	6	designation	designation	NN
cord-322904-9mta0aem	17	7	within	within	IN
cord-322904-9mta0aem	17	8	the	the	DT
cord-322904-9mta0aem	17	9	virus	virus	NN
cord-322904-9mta0aem	17	10	family	family	NN
cord-322904-9mta0aem	17	11	(	(	-LRB-
cord-322904-9mta0aem	17	12	Polyomavirus	Polyomavirus	NNP
cord-322904-9mta0aem	17	13	)	)	-RRB-
cord-322904-9mta0aem	17	14	and	and	CC
cord-322904-9mta0aem	17	15	this	this	DT
cord-322904-9mta0aem	17	16	genus	genus	NN
cord-322904-9mta0aem	17	17	contains	contain	VBZ
cord-322904-9mta0aem	17	18	14	14	CD
cord-322904-9mta0aem	17	19	different	different	JJ
cord-322904-9mta0aem	17	20	species	specie	NNS
cord-322904-9mta0aem	17	21	that	that	WDT
cord-322904-9mta0aem	17	22	infect	infect	VBP
cord-322904-9mta0aem	17	23	at	at	IN
cord-322904-9mta0aem	17	24	least	least	JJS
cord-322904-9mta0aem	17	25	8	8	CD
cord-322904-9mta0aem	17	26	different	different	JJ
cord-322904-9mta0aem	17	27	mammalian	mammalian	JJ
cord-322904-9mta0aem	17	28	species	specie	NNS
cord-322904-9mta0aem	17	29	.	.	.
cord-322904-9mta0aem	18	1	In	in	IN
cord-322904-9mta0aem	18	2	addition	addition	NN
cord-322904-9mta0aem	18	3	to	to	IN
cord-322904-9mta0aem	18	4	containing	contain	VBG
cord-322904-9mta0aem	18	5	dsDNA	dsdna	RB
cord-322904-9mta0aem	18	6	genomes	genome	NNS
cord-322904-9mta0aem	18	7	all	all	DT
cord-322904-9mta0aem	18	8	members	member	NNS
cord-322904-9mta0aem	18	9	of	of	IN
cord-322904-9mta0aem	18	10	this	this	DT
cord-322904-9mta0aem	18	11	virus	virus	NN
cord-322904-9mta0aem	18	12	family	family	NN
cord-322904-9mta0aem	18	13	are	be	VBP
cord-322904-9mta0aem	18	14	non	non	JJ
cord-322904-9mta0aem	18	15	-	-	JJ
cord-322904-9mta0aem	18	16	enveloped	enveloped	JJ
cord-322904-9mta0aem	18	17	.	.	.
cord-322904-9mta0aem	19	1	The	the	DT
cord-322904-9mta0aem	19	2	members	member	NNS
cord-322904-9mta0aem	19	3	of	of	IN
cord-322904-9mta0aem	19	4	the	the	DT
cord-322904-9mta0aem	19	5	family	family	NN
cord-322904-9mta0aem	19	6	typically	typically	RB
cord-322904-9mta0aem	19	7	display	display	VBP
cord-322904-9mta0aem	19	8	restricted	restrict	VBN
cord-322904-9mta0aem	19	9	species	specie	NNS
cord-322904-9mta0aem	19	10	and	and	CC
cord-322904-9mta0aem	19	11	cell	cell	NN
cord-322904-9mta0aem	19	12	type	type	NN
cord-322904-9mta0aem	19	13	specificity	specificity	NN
cord-322904-9mta0aem	19	14	for	for	IN
cord-322904-9mta0aem	19	15	lytic	lytic	JJ
cord-322904-9mta0aem	19	16	infection	infection	NN
cord-322904-9mta0aem	19	17	but	but	CC
cord-322904-9mta0aem	19	18	many	many	JJ
cord-322904-9mta0aem	19	19	can	can	MD
cord-322904-9mta0aem	19	20	induce	induce	VB
cord-322904-9mta0aem	19	21	the	the	DT
cord-322904-9mta0aem	19	22	transformation	transformation	NN
cord-322904-9mta0aem	19	23	of	of	IN
cord-322904-9mta0aem	19	24	cells	cell	NNS
cord-322904-9mta0aem	19	25	that	that	WDT
cord-322904-9mta0aem	19	26	do	do	VBP
cord-322904-9mta0aem	19	27	not	not	RB
cord-322904-9mta0aem	19	28	support	support	VB
cord-322904-9mta0aem	19	29	lytic	lytic	JJ
cord-322904-9mta0aem	19	30	infection	infection	NN
cord-322904-9mta0aem	19	31	.	.	.
cord-322904-9mta0aem	20	1	Host	host	NN
cord-322904-9mta0aem	20	2	cell	cell	NN
cord-322904-9mta0aem	20	3	and	and	CC
cord-322904-9mta0aem	20	4	species	species	NN
cord-322904-9mta0aem	20	5	-	-	HYPH
cord-322904-9mta0aem	20	6	specific	specific	JJ
cord-322904-9mta0aem	20	7	transcription	transcription	NN
cord-322904-9mta0aem	20	8	and	and	CC
cord-322904-9mta0aem	20	9	replication	replication	NN
cord-322904-9mta0aem	20	10	factors	factor	NNS
cord-322904-9mta0aem	20	11	contribute	contribute	VBP
cord-322904-9mta0aem	20	12	significantly	significantly	RB
cord-322904-9mta0aem	20	13	to	to	IN
cord-322904-9mta0aem	20	14	the	the	DT
cord-322904-9mta0aem	20	15	restricted	restrict	VBN
cord-322904-9mta0aem	20	16	specificity	specificity	NN
cord-322904-9mta0aem	20	17	displayed	display	VBN
cord-322904-9mta0aem	20	18	by	by	IN
cord-322904-9mta0aem	20	19	these	these	DT
cord-322904-9mta0aem	20	20	viruses	virus	NNS
cord-322904-9mta0aem	20	21	(	(	-LRB-
cord-322904-9mta0aem	20	22	Feigenbaum	Feigenbaum	NNP
cord-322904-9mta0aem	20	23	et	et	NNP
cord-322904-9mta0aem	20	24	al	al	NNP
cord-322904-9mta0aem	20	25	.	.	NNP
cord-322904-9mta0aem	20	26	,	,	,
cord-322904-9mta0aem	20	27	1987	1987	CD
cord-322904-9mta0aem	20	28	;	;	:
cord-322904-9mta0aem	20	29	Lynch	Lynch	NNP
cord-322904-9mta0aem	20	30	and	and	CC
cord-322904-9mta0aem	20	31	Frisque	Frisque	NNP
cord-322904-9mta0aem	20	32	,	,	,
cord-322904-9mta0aem	20	33	1991	1991	CD
cord-322904-9mta0aem	20	34	;	;	:
cord-322904-9mta0aem	20	35	Tada	Tada	NNP
cord-322904-9mta0aem	20	36	et	et	NNP
cord-322904-9mta0aem	20	37	al	al	NNP
cord-322904-9mta0aem	20	38	.	.	NNP
cord-322904-9mta0aem	20	39	,	,	,
cord-322904-9mta0aem	20	40	1989	1989	CD
cord-322904-9mta0aem	20	41	)	)	-RRB-
cord-322904-9mta0aem	20	42	.	.	.
cord-322904-9mta0aem	21	1	Virus	virus	NN
cord-322904-9mta0aem	21	2	-	-	HYPH
cord-322904-9mta0aem	21	3	receptor	receptor	NN
cord-322904-9mta0aem	21	4	interactions	interaction	NNS
cord-322904-9mta0aem	21	5	are	be	VBP
cord-322904-9mta0aem	21	6	also	also	RB
cord-322904-9mta0aem	21	7	known	know	VBN
cord-322904-9mta0aem	21	8	to	to	TO
cord-322904-9mta0aem	21	9	contribute	contribute	VB
cord-322904-9mta0aem	21	10	to	to	IN
cord-322904-9mta0aem	21	11	cell	cell	NN
cord-322904-9mta0aem	21	12	type	type	NN
cord-322904-9mta0aem	21	13	specificity	specificity	NN
cord-322904-9mta0aem	21	14	and	and	CC
cord-322904-9mta0aem	21	15	more	more	RBR
cord-322904-9mta0aem	21	16	importantly	importantly	RB
cord-322904-9mta0aem	21	17	to	to	TO
cord-322904-9mta0aem	21	18	pathogenesis	pathogenesis	VB
cord-322904-9mta0aem	21	19	in	in	IN
cord-322904-9mta0aem	21	20	vivo	vivo	NN
cord-322904-9mta0aem	22	1	(	(	-LRB-
cord-322904-9mta0aem	22	2	Caruso	Caruso	NNP
cord-322904-9mta0aem	22	3	et	et	NNP
cord-322904-9mta0aem	22	4	al	al	NNP
cord-322904-9mta0aem	22	5	.	.	NNP
cord-322904-9mta0aem	22	6	,	,	,
cord-322904-9mta0aem	22	7	2007	2007	CD
cord-322904-9mta0aem	23	1	;	;	:
cord-322904-9mta0aem	23	2	Chen	Chen	NNP
cord-322904-9mta0aem	23	3	and	and	CC
cord-322904-9mta0aem	23	4	Atwood	Atwood	NNP
cord-322904-9mta0aem	23	5	,	,	,
cord-322904-9mta0aem	23	6	2002	2002	CD
cord-322904-9mta0aem	23	7	;	;	:
cord-322904-9mta0aem	23	8	Dubensky	Dubensky	NNP
cord-322904-9mta0aem	23	9	et	et	FW
cord-322904-9mta0aem	23	10	al	al	NNP
cord-322904-9mta0aem	23	11	.	.	NNP
cord-322904-9mta0aem	23	12	,	,	,
cord-322904-9mta0aem	23	13	1991	1991	CD
cord-322904-9mta0aem	23	14	;	;	:
cord-322904-9mta0aem	23	15	Freund	Freund	NNP
cord-322904-9mta0aem	23	16	et	et	NNP
cord-322904-9mta0aem	23	17	al	al	NNP
cord-322904-9mta0aem	23	18	.	.	NNP
cord-322904-9mta0aem	23	19	,	,	,
cord-322904-9mta0aem	23	20	1991a	1991a	CD
cord-322904-9mta0aem	23	21	;	;	:
cord-322904-9mta0aem	24	1	Freund	Freund	NNP
cord-322904-9mta0aem	24	2	et	et	NNP
cord-322904-9mta0aem	24	3	al	al	NNP
cord-322904-9mta0aem	24	4	.	.	NNP
cord-322904-9mta0aem	24	5	,	,	,
cord-322904-9mta0aem	24	6	1991b	1991b	CD
cord-322904-9mta0aem	24	7	;	;	:
cord-322904-9mta0aem	24	8	Fried	Fried	NNP
cord-322904-9mta0aem	24	9	et	et	FW
cord-322904-9mta0aem	24	10	al	al	NNP
cord-322904-9mta0aem	24	11	.	.	NNP
cord-322904-9mta0aem	24	12	,	,	,
cord-322904-9mta0aem	24	13	1981	1981	CD
cord-322904-9mta0aem	24	14	)	)	-RRB-
cord-322904-9mta0aem	24	15	.	.	.
cord-322904-9mta0aem	25	1	Like	like	IN
cord-322904-9mta0aem	25	2	many	many	JJ
cord-322904-9mta0aem	25	3	other	other	JJ
cord-322904-9mta0aem	25	4	virus	virus	NN
cord-322904-9mta0aem	25	5	families	family	NNS
cord-322904-9mta0aem	25	6	the	the	DT
cord-322904-9mta0aem	25	7	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	25	8	use	use	VBP
cord-322904-9mta0aem	25	9	multiple	multiple	NN
cord-322904-9mta0aem	25	10	and	and	CC
cord-322904-9mta0aem	25	11	often	often	RB
cord-322904-9mta0aem	25	12	distinct	distinct	JJ
cord-322904-9mta0aem	25	13	receptors	receptor	NNS
cord-322904-9mta0aem	25	14	and	and	CC
cord-322904-9mta0aem	25	15	entry	entry	NN
cord-322904-9mta0aem	25	16	mechanisms	mechanism	NNS
cord-322904-9mta0aem	25	17	to	to	TO
cord-322904-9mta0aem	25	18	infect	infect	VB
cord-322904-9mta0aem	25	19	cells	cell	NNS
cord-322904-9mta0aem	25	20	.	.	.
cord-322904-9mta0aem	26	1	At	at	IN
cord-322904-9mta0aem	26	2	high	high	JJ
cord-322904-9mta0aem	26	3	enough	enough	JJ
cord-322904-9mta0aem	26	4	multiplicities	multiplicity	NNS
cord-322904-9mta0aem	26	5	many	many	JJ
cord-322904-9mta0aem	26	6	of	of	IN
cord-322904-9mta0aem	26	7	these	these	DT
cord-322904-9mta0aem	26	8	viruses	virus	NNS
cord-322904-9mta0aem	26	9	can	can	MD
cord-322904-9mta0aem	26	10	infect	infect	VB
cord-322904-9mta0aem	26	11	cells	cell	NNS
cord-322904-9mta0aem	26	12	using	use	VBG
cord-322904-9mta0aem	26	13	alternative	alternative	NN
cord-322904-9mta0aem	26	14	often	often	RB
cord-322904-9mta0aem	26	15	poorly	poorly	RB
cord-322904-9mta0aem	26	16	described	describe	VBN
cord-322904-9mta0aem	26	17	mechanisms	mechanism	NNS
cord-322904-9mta0aem	26	18	.	.	.
cord-322904-9mta0aem	27	1	The	the	DT
cord-322904-9mta0aem	27	2	structures	structure	NNS
cord-322904-9mta0aem	27	3	of	of	IN
cord-322904-9mta0aem	27	4	two	two	CD
cord-322904-9mta0aem	27	5	major	major	JJ
cord-322904-9mta0aem	27	6	members	member	NNS
cord-322904-9mta0aem	27	7	of	of	IN
cord-322904-9mta0aem	27	8	the	the	DT
cord-322904-9mta0aem	27	9	family	family	NN
cord-322904-9mta0aem	27	10	have	have	VBP
cord-322904-9mta0aem	27	11	been	be	VBN
cord-322904-9mta0aem	27	12	solved	solve	VBN
cord-322904-9mta0aem	27	13	in	in	IN
cord-322904-9mta0aem	27	14	complex	complex	NN
cord-322904-9mta0aem	27	15	with	with	IN
cord-322904-9mta0aem	27	16	receptor	receptor	NN
cord-322904-9mta0aem	27	17	fragments	fragment	NNS
cord-322904-9mta0aem	27	18	and	and	CC
cord-322904-9mta0aem	27	19	this	this	DT
cord-322904-9mta0aem	27	20	has	have	VBZ
cord-322904-9mta0aem	27	21	given	give	VBN
cord-322904-9mta0aem	27	22	insight	insight	NN
cord-322904-9mta0aem	27	23	into	into	IN
cord-322904-9mta0aem	27	24	how	how	WRB
cord-322904-9mta0aem	27	25	these	these	DT
cord-322904-9mta0aem	27	26	viruses	virus	NNS
cord-322904-9mta0aem	27	27	recognize	recognize	VBP
cord-322904-9mta0aem	27	28	host	host	NN
cord-322904-9mta0aem	27	29	cells	cell	NNS
cord-322904-9mta0aem	27	30	(	(	-LRB-
cord-322904-9mta0aem	27	31	Liddington	Liddington	NNP
cord-322904-9mta0aem	27	32	et	et	FW
cord-322904-9mta0aem	27	33	al	al	NNP
cord-322904-9mta0aem	27	34	.	.	NNP
cord-322904-9mta0aem	27	35	,	,	,
cord-322904-9mta0aem	27	36	1991	1991	CD
cord-322904-9mta0aem	27	37	;	;	:
cord-322904-9mta0aem	27	38	Neu	Neu	NNP
cord-322904-9mta0aem	27	39	et	et	FW
cord-322904-9mta0aem	27	40	al	al	NNP
cord-322904-9mta0aem	27	41	.	.	NNP
cord-322904-9mta0aem	27	42	,	,	,
cord-322904-9mta0aem	27	43	2008	2008	CD
cord-322904-9mta0aem	27	44	;	;	:
cord-322904-9mta0aem	27	45	Stehle	Stehle	NNP
cord-322904-9mta0aem	27	46	and	and	CC
cord-322904-9mta0aem	27	47	Harrison	Harrison	NNP
cord-322904-9mta0aem	27	48	,	,	,
cord-322904-9mta0aem	27	49	1997	1997	CD
cord-322904-9mta0aem	27	50	;	;	:
cord-322904-9mta0aem	27	51	Stehle	Stehle	NNP
cord-322904-9mta0aem	27	52	et	et	FW
cord-322904-9mta0aem	27	53	al	al	NNP
cord-322904-9mta0aem	27	54	.	.	NNP
cord-322904-9mta0aem	27	55	,	,	,
cord-322904-9mta0aem	27	56	1994	1994	CD
cord-322904-9mta0aem	27	57	)	)	-RRB-
cord-322904-9mta0aem	27	58	.	.	.
cord-322904-9mta0aem	28	1	A	a	DT
cord-322904-9mta0aem	28	2	major	major	JJ
cord-322904-9mta0aem	28	3	area	area	NN
cord-322904-9mta0aem	28	4	of	of	IN
cord-322904-9mta0aem	28	5	current	current	JJ
cord-322904-9mta0aem	28	6	investigation	investigation	NN
cord-322904-9mta0aem	28	7	by	by	IN
cord-322904-9mta0aem	28	8	several	several	JJ
cord-322904-9mta0aem	28	9	labs	lab	NNS
cord-322904-9mta0aem	28	10	is	be	VBZ
cord-322904-9mta0aem	28	11	focused	focus	VBN
cord-322904-9mta0aem	28	12	on	on	IN
cord-322904-9mta0aem	28	13	understanding	understand	VBG
cord-322904-9mta0aem	28	14	the	the	DT
cord-322904-9mta0aem	28	15	intracellular	intracellular	JJ
cord-322904-9mta0aem	28	16	trafficking	trafficking	NN
cord-322904-9mta0aem	28	17	of	of	IN
cord-322904-9mta0aem	28	18	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	28	19	in	in	IN
cord-322904-9mta0aem	28	20	host	host	NN
cord-322904-9mta0aem	28	21	cells	cell	NNS
cord-322904-9mta0aem	28	22	and	and	CC
cord-322904-9mta0aem	28	23	the	the	DT
cord-322904-9mta0aem	28	24	mechanisms	mechanism	NNS
cord-322904-9mta0aem	28	25	involved	involve	VBN
cord-322904-9mta0aem	28	26	in	in	IN
cord-322904-9mta0aem	28	27	virus	virus	NN
cord-322904-9mta0aem	28	28	uncoating	uncoating	NN
cord-322904-9mta0aem	28	29	and	and	CC
cord-322904-9mta0aem	28	30	delivery	delivery	NN
cord-322904-9mta0aem	28	31	of	of	IN
cord-322904-9mta0aem	28	32	the	the	DT
cord-322904-9mta0aem	28	33	dsDNA	dsdna	JJ
cord-322904-9mta0aem	28	34	genomes	genome	NNS
cord-322904-9mta0aem	28	35	to	to	IN
cord-322904-9mta0aem	28	36	the	the	DT
cord-322904-9mta0aem	28	37	nucleus	nucleus	NN
cord-322904-9mta0aem	28	38	.	.	.
cord-322904-9mta0aem	29	1	This	this	DT
cord-322904-9mta0aem	29	2	paper	paper	NN
cord-322904-9mta0aem	29	3	will	will	MD
cord-322904-9mta0aem	29	4	overview	overview	VB
cord-322904-9mta0aem	29	5	the	the	DT
cord-322904-9mta0aem	29	6	field	field	NN
cord-322904-9mta0aem	29	7	of	of	IN
cord-322904-9mta0aem	29	8	virus	virus	NN
cord-322904-9mta0aem	29	9	structure	structure	NN
cord-322904-9mta0aem	29	10	and	and	CC
cord-322904-9mta0aem	29	11	entry	entry	NN
cord-322904-9mta0aem	29	12	from	from	IN
cord-322904-9mta0aem	29	13	its	-PRON-	PRP$
cord-322904-9mta0aem	29	14	beginnings	beginning	NNS
cord-322904-9mta0aem	29	15	to	to	IN
cord-322904-9mta0aem	29	16	the	the	DT
cord-322904-9mta0aem	29	17	present	present	NN
cord-322904-9mta0aem	29	18	.	.	.
cord-322904-9mta0aem	30	1	The	the	DT
cord-322904-9mta0aem	30	2	focus	focus	NN
cord-322904-9mta0aem	30	3	will	will	MD
cord-322904-9mta0aem	30	4	be	be	VB
cord-322904-9mta0aem	30	5	on	on	IN
cord-322904-9mta0aem	30	6	the	the	DT
cord-322904-9mta0aem	30	7	mouse	mouse	NN
cord-322904-9mta0aem	30	8	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	30	9	,	,	,
cord-322904-9mta0aem	30	10	on	on	IN
cord-322904-9mta0aem	30	11	SV40	SV40	NNP
cord-322904-9mta0aem	30	12	,	,	,
cord-322904-9mta0aem	30	13	and	and	CC
cord-322904-9mta0aem	30	14	on	on	IN
cord-322904-9mta0aem	30	15	the	the	DT
cord-322904-9mta0aem	30	16	two	two	CD
cord-322904-9mta0aem	30	17	major	major	JJ
cord-322904-9mta0aem	30	18	human	human	JJ
cord-322904-9mta0aem	30	19	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	30	20	,	,	,
cord-322904-9mta0aem	30	21	JCV	JCV	NNP
cord-322904-9mta0aem	30	22	and	and	CC
cord-322904-9mta0aem	30	23	BKV	BKV	NNP
cord-322904-9mta0aem	30	24	.	.	.
cord-322904-9mta0aem	31	1	The	the	DT
cord-322904-9mta0aem	31	2	mouse	mouse	NN
cord-322904-9mta0aem	31	3	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	31	4	(	(	-LRB-
cord-322904-9mta0aem	31	5	mPyV	mPyV	NNP
cord-322904-9mta0aem	31	6	)	)	-RRB-
cord-322904-9mta0aem	31	7	was	be	VBD
cord-322904-9mta0aem	31	8	first	first	RB
cord-322904-9mta0aem	31	9	described	describe	VBN
cord-322904-9mta0aem	31	10	by	by	IN
cord-322904-9mta0aem	31	11	Ludwig	Ludwig	NNP
cord-322904-9mta0aem	31	12	Gross	Gross	NNP
cord-322904-9mta0aem	31	13	in	in	IN
cord-322904-9mta0aem	31	14	1953	1953	CD
cord-322904-9mta0aem	31	15	in	in	IN
cord-322904-9mta0aem	31	16	his	-PRON-	PRP$
cord-322904-9mta0aem	31	17	studies	study	NNS
cord-322904-9mta0aem	31	18	on	on	IN
cord-322904-9mta0aem	31	19	the	the	DT
cord-322904-9mta0aem	31	20	transmission	transmission	NN
cord-322904-9mta0aem	31	21	of	of	IN
cord-322904-9mta0aem	31	22	mouse	mouse	NN
cord-322904-9mta0aem	31	23	leukemias	leukemia	NNS
cord-322904-9mta0aem	31	24	(	(	-LRB-
cord-322904-9mta0aem	31	25	Gross	gross	JJ
cord-322904-9mta0aem	31	26	,	,	,
cord-322904-9mta0aem	31	27	1953	1953	CD
cord-322904-9mta0aem	31	28	)	)	-RRB-
cord-322904-9mta0aem	31	29	.	.	.
cord-322904-9mta0aem	32	1	He	-PRON-	PRP
cord-322904-9mta0aem	32	2	noticed	notice	VBD
cord-322904-9mta0aem	32	3	that	that	IN
cord-322904-9mta0aem	32	4	mice	mouse	NNS
cord-322904-9mta0aem	32	5	inoculated	inoculate	VBN
cord-322904-9mta0aem	32	6	with	with	IN
cord-322904-9mta0aem	32	7	cell	cell	NN
cord-322904-9mta0aem	32	8	free	free	JJ
cord-322904-9mta0aem	32	9	extracts	extract	NNS
cord-322904-9mta0aem	32	10	from	from	IN
cord-322904-9mta0aem	32	11	leukemias	leukemia	NNS
cord-322904-9mta0aem	32	12	were	be	VBD
cord-322904-9mta0aem	32	13	capable	capable	JJ
cord-322904-9mta0aem	32	14	of	of	IN
cord-322904-9mta0aem	32	15	not	not	RB
cord-322904-9mta0aem	32	16	only	only	RB
cord-322904-9mta0aem	32	17	transmitting	transmit	VBG
cord-322904-9mta0aem	32	18	leukemia	leukemia	NN
cord-322904-9mta0aem	32	19	to	to	IN
cord-322904-9mta0aem	32	20	naïve	naïve	JJ
cord-322904-9mta0aem	32	21	animals	animal	NNS
cord-322904-9mta0aem	32	22	but	but	CC
cord-322904-9mta0aem	32	23	that	that	IN
cord-322904-9mta0aem	32	24	some	some	DT
cord-322904-9mta0aem	32	25	of	of	IN
cord-322904-9mta0aem	32	26	the	the	DT
cord-322904-9mta0aem	32	27	animals	animal	NNS
cord-322904-9mta0aem	32	28	also	also	RB
cord-322904-9mta0aem	32	29	developed	develop	VBD
cord-322904-9mta0aem	32	30	parotid	parotid	JJ
cord-322904-9mta0aem	32	31	tumors	tumor	NNS
cord-322904-9mta0aem	32	32	.	.	.
cord-322904-9mta0aem	33	1	In	in	IN
cord-322904-9mta0aem	33	2	classic	classic	JJ
cord-322904-9mta0aem	33	3	experiments	experiment	NNS
cord-322904-9mta0aem	33	4	he	-PRON-	PRP
cord-322904-9mta0aem	33	5	found	find	VBD
cord-322904-9mta0aem	33	6	that	that	IN
cord-322904-9mta0aem	33	7	the	the	DT
cord-322904-9mta0aem	33	8	"	"	``
cord-322904-9mta0aem	33	9	parotid	parotid	JJ
cord-322904-9mta0aem	33	10	"	"	''
cord-322904-9mta0aem	33	11	agent	agent	NN
cord-322904-9mta0aem	33	12	could	could	MD
cord-322904-9mta0aem	33	13	be	be	VB
cord-322904-9mta0aem	33	14	distinguished	distinguish	VBN
cord-322904-9mta0aem	33	15	from	from	IN
cord-322904-9mta0aem	33	16	the	the	DT
cord-322904-9mta0aem	33	17	mouse	mouse	NN
cord-322904-9mta0aem	33	18	leukemia	leukemia	NN
cord-322904-9mta0aem	33	19	virus	virus	NN
cord-322904-9mta0aem	33	20	by	by	IN
cord-322904-9mta0aem	33	21	filtration	filtration	NN
cord-322904-9mta0aem	33	22	.	.	.
cord-322904-9mta0aem	34	1	Filters	filter	NNS
cord-322904-9mta0aem	34	2	with	with	IN
cord-322904-9mta0aem	34	3	larger	large	JJR
cord-322904-9mta0aem	34	4	pore	pore	NN
cord-322904-9mta0aem	34	5	sizes	size	NNS
cord-322904-9mta0aem	34	6	allowed	allow	VBD
cord-322904-9mta0aem	34	7	both	both	DT
cord-322904-9mta0aem	34	8	viruses	virus	NNS
cord-322904-9mta0aem	34	9	to	to	TO
cord-322904-9mta0aem	34	10	pass	pass	VB
cord-322904-9mta0aem	34	11	but	but	CC
cord-322904-9mta0aem	34	12	filters	filter	NNS
cord-322904-9mta0aem	34	13	of	of	IN
cord-322904-9mta0aem	34	14	smaller	small	JJR
cord-322904-9mta0aem	34	15	pore	pore	NN
cord-322904-9mta0aem	34	16	size	size	NN
cord-322904-9mta0aem	34	17	selectively	selectively	RB
cord-322904-9mta0aem	34	18	trapped	trap	VBD
cord-322904-9mta0aem	34	19	the	the	DT
cord-322904-9mta0aem	34	20	leukemia	leukemia	NN
cord-322904-9mta0aem	34	21	agent	agent	NN
cord-322904-9mta0aem	34	22	indicating	indicate	VBG
cord-322904-9mta0aem	34	23	Virology	Virology	NNP
cord-322904-9mta0aem	34	24	384	384	CD
cord-322904-9mta0aem	34	25	(	(	-LRB-
cord-322904-9mta0aem	34	26	2009	2009	CD
cord-322904-9mta0aem	34	27	)	)	-RRB-
cord-322904-9mta0aem	35	1	[	[	-LRB-
cord-322904-9mta0aem	35	2	389	389	CD
cord-322904-9mta0aem	35	3	]	]	-RRB-
cord-322904-9mta0aem	35	4	[	[	-LRB-
cord-322904-9mta0aem	35	5	390	390	CD
cord-322904-9mta0aem	35	6	]	]	-RRB-
cord-322904-9mta0aem	35	7	[	[	-LRB-
cord-322904-9mta0aem	35	8	391	391	CD
cord-322904-9mta0aem	35	9	]	]	-RRB-
cord-322904-9mta0aem	35	10	[	[	-LRB-
cord-322904-9mta0aem	35	11	392	392	CD
cord-322904-9mta0aem	35	12	]	]	-RRB-
cord-322904-9mta0aem	35	13	[	[	-LRB-
cord-322904-9mta0aem	35	14	393	393	CD
cord-322904-9mta0aem	35	15	]	]	-RRB-
cord-322904-9mta0aem	35	16	[	[	-LRB-
cord-322904-9mta0aem	35	17	394	394	CD
cord-322904-9mta0aem	35	18	]	]	-RRB-
cord-322904-9mta0aem	35	19	[	[	-LRB-
cord-322904-9mta0aem	35	20	395	395	CD
cord-322904-9mta0aem	35	21	]	]	-RRB-
cord-322904-9mta0aem	35	22	[	[	-LRB-
cord-322904-9mta0aem	35	23	396	396	CD
cord-322904-9mta0aem	35	24	]	]	-RRB-
cord-322904-9mta0aem	35	25	[	[	-LRB-
cord-322904-9mta0aem	35	26	397	397	CD
cord-322904-9mta0aem	35	27	]	]	-RRB-
cord-322904-9mta0aem	35	28	[	[	-LRB-
cord-322904-9mta0aem	35	29	398	398	CD
cord-322904-9mta0aem	35	30	]	]	-RRB-
cord-322904-9mta0aem	35	31	[	[	-LRB-
cord-322904-9mta0aem	35	32	399	399	CD
cord-322904-9mta0aem	35	33	]	]	-RRB-
cord-322904-9mta0aem	35	34	that	that	IN
cord-322904-9mta0aem	35	35	the	the	DT
cord-322904-9mta0aem	35	36	parotid	parotid	JJ
cord-322904-9mta0aem	35	37	agent	agent	NN
cord-322904-9mta0aem	35	38	was	be	VBD
cord-322904-9mta0aem	35	39	smaller	small	JJR
cord-322904-9mta0aem	35	40	than	than	IN
cord-322904-9mta0aem	35	41	the	the	DT
cord-322904-9mta0aem	35	42	leukemia	leukemia	NN
cord-322904-9mta0aem	35	43	virus	virus	NN
cord-322904-9mta0aem	35	44	.	.	.
cord-322904-9mta0aem	36	1	In	in	IN
cord-322904-9mta0aem	36	2	the	the	DT
cord-322904-9mta0aem	36	3	mid	mid	NN
cord-322904-9mta0aem	36	4	to	to	IN
cord-322904-9mta0aem	36	5	late	late	JJ
cord-322904-9mta0aem	36	6	1950s	1950	NNS
cord-322904-9mta0aem	36	7	Stewart	Stewart	NNP
cord-322904-9mta0aem	36	8	and	and	CC
cord-322904-9mta0aem	36	9	Eddy	Eddy	NNP
cord-322904-9mta0aem	36	10	followed	follow	VBD
cord-322904-9mta0aem	36	11	up	up	RP
cord-322904-9mta0aem	36	12	on	on	IN
cord-322904-9mta0aem	36	13	these	these	DT
cord-322904-9mta0aem	36	14	observations	observation	NNS
cord-322904-9mta0aem	36	15	and	and	CC
cord-322904-9mta0aem	36	16	found	find	VBD
cord-322904-9mta0aem	36	17	that	that	IN
cord-322904-9mta0aem	36	18	the	the	DT
cord-322904-9mta0aem	36	19	"	"	``
cord-322904-9mta0aem	36	20	parotid	parotid	JJ
cord-322904-9mta0aem	36	21	"	"	''
cord-322904-9mta0aem	36	22	agent	agent	NN
cord-322904-9mta0aem	36	23	was	be	VBD
cord-322904-9mta0aem	36	24	capable	capable	JJ
cord-322904-9mta0aem	36	25	of	of	IN
cord-322904-9mta0aem	36	26	inducing	induce	VBG
cord-322904-9mta0aem	36	27	many	many	JJ
cord-322904-9mta0aem	36	28	different	different	JJ
cord-322904-9mta0aem	36	29	types	type	NNS
cord-322904-9mta0aem	36	30	of	of	IN
cord-322904-9mta0aem	36	31	tumors	tumor	NNS
cord-322904-9mta0aem	36	32	when	when	WRB
cord-322904-9mta0aem	36	33	inoculated	inoculate	VBN
cord-322904-9mta0aem	36	34	into	into	IN
cord-322904-9mta0aem	36	35	mice	mouse	NNS
cord-322904-9mta0aem	36	36	and	and	CC
cord-322904-9mta0aem	36	37	renamed	rename	VBD
cord-322904-9mta0aem	36	38	the	the	DT
cord-322904-9mta0aem	36	39	virus	virus	NN
cord-322904-9mta0aem	36	40	"	"	``
cord-322904-9mta0aem	36	41	poly"oma	poly"oma	NNP
cord-322904-9mta0aem	36	42	from	from	IN
cord-322904-9mta0aem	36	43	the	the	DT
cord-322904-9mta0aem	36	44	Greek	Greek	NNP
cord-322904-9mta0aem	36	45	for	for	IN
cord-322904-9mta0aem	36	46	many	many	JJ
cord-322904-9mta0aem	36	47	tumors	tumor	NNS
cord-322904-9mta0aem	36	48	Stewart	Stewart	NNP
cord-322904-9mta0aem	36	49	et	et	NNP
cord-322904-9mta0aem	36	50	al	al	NNP
cord-322904-9mta0aem	36	51	.	.	NNP
cord-322904-9mta0aem	36	52	,	,	,
cord-322904-9mta0aem	36	53	1958	1958	CD
cord-322904-9mta0aem	36	54	)	)	-RRB-
cord-322904-9mta0aem	36	55	.	.	.
cord-322904-9mta0aem	37	1	SV40	SV40	NNP
cord-322904-9mta0aem	37	2	was	be	VBD
cord-322904-9mta0aem	37	3	discovered	discover	VBN
cord-322904-9mta0aem	37	4	as	as	IN
cord-322904-9mta0aem	37	5	a	a	DT
cord-322904-9mta0aem	37	6	contaminant	contaminant	NN
cord-322904-9mta0aem	37	7	of	of	IN
cord-322904-9mta0aem	37	8	formalin	formalin	NN
cord-322904-9mta0aem	37	9	inactivated	inactivate	VBN
cord-322904-9mta0aem	37	10	polioviruses	poliovirus	NNS
cord-322904-9mta0aem	37	11	that	that	WDT
cord-322904-9mta0aem	37	12	were	be	VBD
cord-322904-9mta0aem	37	13	grown	grow	VBN
cord-322904-9mta0aem	37	14	in	in	IN
cord-322904-9mta0aem	37	15	Rhesus	Rhesus	NNP
cord-322904-9mta0aem	37	16	monkey	monkey	NN
cord-322904-9mta0aem	37	17	kidney	kidney	NN
cord-322904-9mta0aem	37	18	cells	cell	NNS
cord-322904-9mta0aem	37	19	(	(	-LRB-
cord-322904-9mta0aem	37	20	Sweet	Sweet	NNP
cord-322904-9mta0aem	37	21	and	and	CC
cord-322904-9mta0aem	37	22	Hilleman	Hilleman	NNP
cord-322904-9mta0aem	37	23	,	,	,
cord-322904-9mta0aem	37	24	1960	1960	CD
cord-322904-9mta0aem	37	25	)	)	-RRB-
cord-322904-9mta0aem	37	26	.	.	.
cord-322904-9mta0aem	38	1	The	the	DT
cord-322904-9mta0aem	38	2	subsequent	subsequent	JJ
cord-322904-9mta0aem	38	3	characterization	characterization	NN
cord-322904-9mta0aem	38	4	of	of	IN
cord-322904-9mta0aem	38	5	this	this	DT
cord-322904-9mta0aem	38	6	virus	virus	NN
cord-322904-9mta0aem	38	7	as	as	IN
cord-322904-9mta0aem	38	8	a	a	DT
cord-322904-9mta0aem	38	9	papovavirus	papovavirus	NN
cord-322904-9mta0aem	38	10	capable	capable	JJ
cord-322904-9mta0aem	38	11	of	of	IN
cord-322904-9mta0aem	38	12	transforming	transform	VBG
cord-322904-9mta0aem	38	13	cells	cell	NNS
cord-322904-9mta0aem	38	14	in	in	IN
cord-322904-9mta0aem	38	15	vitro	vitro	FW
cord-322904-9mta0aem	38	16	and	and	CC
cord-322904-9mta0aem	38	17	inducing	induce	VBG
cord-322904-9mta0aem	38	18	tumors	tumor	NNS
cord-322904-9mta0aem	38	19	in	in	IN
cord-322904-9mta0aem	38	20	experimental	experimental	JJ
cord-322904-9mta0aem	38	21	animals	animal	NNS
cord-322904-9mta0aem	38	22	was	be	VBD
cord-322904-9mta0aem	38	23	a	a	DT
cord-322904-9mta0aem	38	24	cause	cause	NN
cord-322904-9mta0aem	38	25	for	for	IN
cord-322904-9mta0aem	38	26	great	great	JJ
cord-322904-9mta0aem	38	27	concern	concern	NN
cord-322904-9mta0aem	38	28	as	as	IN
cord-322904-9mta0aem	38	29	several	several	JJ
cord-322904-9mta0aem	38	30	hundred	hundred	CD
cord-322904-9mta0aem	38	31	thousand	thousand	CD
cord-322904-9mta0aem	38	32	individuals	individual	NNS
cord-322904-9mta0aem	38	33	were	be	VBD
cord-322904-9mta0aem	38	34	inoculated	inoculate	VBN
cord-322904-9mta0aem	38	35	with	with	IN
cord-322904-9mta0aem	38	36	the	the	DT
cord-322904-9mta0aem	38	37	contaminated	contaminate	VBN
cord-322904-9mta0aem	38	38	vaccine	vaccine	NN
cord-322904-9mta0aem	38	39	(	(	-LRB-
cord-322904-9mta0aem	38	40	Girardi	Girardi	NNP
cord-322904-9mta0aem	38	41	et	et	NNP
cord-322904-9mta0aem	38	42	al	al	NNP
cord-322904-9mta0aem	38	43	.	.	NNP
cord-322904-9mta0aem	38	44	,	,	,
cord-322904-9mta0aem	38	45	1962	1962	CD
cord-322904-9mta0aem	38	46	)	)	-RRB-
cord-322904-9mta0aem	38	47	.	.	.
cord-322904-9mta0aem	39	1	This	this	DT
cord-322904-9mta0aem	39	2	launched	launch	VBD
cord-322904-9mta0aem	39	3	several	several	JJ
cord-322904-9mta0aem	39	4	decades	decade	NNS
cord-322904-9mta0aem	39	5	of	of	IN
cord-322904-9mta0aem	39	6	intensive	intensive	JJ
cord-322904-9mta0aem	39	7	research	research	NN
cord-322904-9mta0aem	39	8	on	on	IN
cord-322904-9mta0aem	39	9	SV40	SV40	NNP
cord-322904-9mta0aem	39	10	.	.	.
cord-322904-9mta0aem	40	1	This	this	DT
cord-322904-9mta0aem	40	2	work	work	NN
cord-322904-9mta0aem	40	3	on	on	IN
cord-322904-9mta0aem	40	4	SV40	SV40	NNP
cord-322904-9mta0aem	40	5	led	lead	VBD
cord-322904-9mta0aem	40	6	to	to	IN
cord-322904-9mta0aem	40	7	the	the	DT
cord-322904-9mta0aem	40	8	discovery	discovery	NN
cord-322904-9mta0aem	40	9	of	of	IN
cord-322904-9mta0aem	40	10	many	many	JJ
cord-322904-9mta0aem	40	11	important	important	JJ
cord-322904-9mta0aem	40	12	cellular	cellular	JJ
cord-322904-9mta0aem	40	13	processes	process	NNS
cord-322904-9mta0aem	40	14	described	describe	VBN
cord-322904-9mta0aem	40	15	elsewhere	elsewhere	RB
cord-322904-9mta0aem	40	16	in	in	IN
cord-322904-9mta0aem	40	17	this	this	DT
cord-322904-9mta0aem	40	18	issue	issue	NN
cord-322904-9mta0aem	40	19	of	of	IN
cord-322904-9mta0aem	40	20	the	the	DT
cord-322904-9mta0aem	40	21	journal	journal	NN
cord-322904-9mta0aem	40	22	.	.	.
cord-322904-9mta0aem	41	1	JCV	JCV	NNP
cord-322904-9mta0aem	41	2	and	and	CC
cord-322904-9mta0aem	41	3	BKV	BKV	NNP
cord-322904-9mta0aem	41	4	were	be	VBD
cord-322904-9mta0aem	41	5	both	both	DT
cord-322904-9mta0aem	41	6	identified	identify	VBN
cord-322904-9mta0aem	41	7	in	in	IN
cord-322904-9mta0aem	41	8	1971	1971	CD
cord-322904-9mta0aem	41	9	from	from	IN
cord-322904-9mta0aem	41	10	immunosuppressed	immunosuppressed	JJ
cord-322904-9mta0aem	41	11	patients	patient	NNS
cord-322904-9mta0aem	41	12	.	.	.
cord-322904-9mta0aem	42	1	JCV	JCV	NNP
cord-322904-9mta0aem	42	2	was	be	VBD
cord-322904-9mta0aem	42	3	islolated	islolate	VBN
cord-322904-9mta0aem	42	4	in	in	IN
cord-322904-9mta0aem	42	5	human	human	JJ
cord-322904-9mta0aem	42	6	fetal	fetal	JJ
cord-322904-9mta0aem	42	7	brain	brain	NN
cord-322904-9mta0aem	42	8	cultures	culture	NNS
cord-322904-9mta0aem	42	9	following	follow	VBG
cord-322904-9mta0aem	42	10	transfer	transfer	NN
cord-322904-9mta0aem	42	11	from	from	IN
cord-322904-9mta0aem	42	12	the	the	DT
cord-322904-9mta0aem	42	13	brain	brain	NN
cord-322904-9mta0aem	42	14	of	of	IN
cord-322904-9mta0aem	42	15	a	a	DT
cord-322904-9mta0aem	42	16	patient	patient	NN
cord-322904-9mta0aem	42	17	with	with	IN
cord-322904-9mta0aem	42	18	PML	PML	NNP
cord-322904-9mta0aem	42	19	(	(	-LRB-
cord-322904-9mta0aem	42	20	Padgett	Padgett	NNP
cord-322904-9mta0aem	42	21	et	et	FW
cord-322904-9mta0aem	42	22	al	al	NNP
cord-322904-9mta0aem	42	23	.	.	NNP
cord-322904-9mta0aem	42	24	,	,	,
cord-322904-9mta0aem	42	25	1971	1971	CD
cord-322904-9mta0aem	42	26	)	)	-RRB-
cord-322904-9mta0aem	42	27	.	.	.
cord-322904-9mta0aem	43	1	It	-PRON-	PRP
cord-322904-9mta0aem	43	2	was	be	VBD
cord-322904-9mta0aem	43	3	given	give	VBN
cord-322904-9mta0aem	43	4	the	the	DT
cord-322904-9mta0aem	43	5	name	name	NN
cord-322904-9mta0aem	43	6	JCV	JCV	NNP
cord-322904-9mta0aem	43	7	after	after	IN
cord-322904-9mta0aem	43	8	the	the	DT
cord-322904-9mta0aem	43	9	patient	patient	NN
cord-322904-9mta0aem	43	10	's	's	POS
cord-322904-9mta0aem	43	11	initials	initial	NNS
cord-322904-9mta0aem	43	12	.	.	.
cord-322904-9mta0aem	44	1	BKV	BKV	NNP
cord-322904-9mta0aem	44	2	was	be	VBD
cord-322904-9mta0aem	44	3	isolated	isolate	VBN
cord-322904-9mta0aem	44	4	in	in	IN
cord-322904-9mta0aem	44	5	VERO	VERO	NNP
cord-322904-9mta0aem	44	6	cells	cell	NNS
cord-322904-9mta0aem	44	7	(	(	-LRB-
cord-322904-9mta0aem	44	8	African	african	JJ
cord-322904-9mta0aem	44	9	green	green	JJ
cord-322904-9mta0aem	44	10	monkey	monkey	NN
cord-322904-9mta0aem	44	11	kidney	kidney	NN
cord-322904-9mta0aem	44	12	cells	cell	NNS
cord-322904-9mta0aem	44	13	)	)	-RRB-
cord-322904-9mta0aem	44	14	from	from	IN
cord-322904-9mta0aem	44	15	the	the	DT
cord-322904-9mta0aem	44	16	urine	urine	NN
cord-322904-9mta0aem	44	17	of	of	IN
cord-322904-9mta0aem	44	18	a	a	DT
cord-322904-9mta0aem	44	19	renal	renal	JJ
cord-322904-9mta0aem	44	20	transplant	transplant	NN
cord-322904-9mta0aem	44	21	recipient	recipient	NN
cord-322904-9mta0aem	44	22	(	(	-LRB-
cord-322904-9mta0aem	44	23	Gardner	Gardner	NNP
cord-322904-9mta0aem	44	24	et	et	NNP
cord-322904-9mta0aem	44	25	al	al	NNP
cord-322904-9mta0aem	44	26	.	.	NNP
cord-322904-9mta0aem	44	27	,	,	,
cord-322904-9mta0aem	44	28	1971	1971	CD
cord-322904-9mta0aem	44	29	)	)	-RRB-
cord-322904-9mta0aem	44	30	.	.	.
cord-322904-9mta0aem	45	1	It	-PRON-	PRP
cord-322904-9mta0aem	45	2	was	be	VBD
cord-322904-9mta0aem	45	3	also	also	RB
cord-322904-9mta0aem	45	4	named	name	VBN
cord-322904-9mta0aem	45	5	after	after	IN
cord-322904-9mta0aem	45	6	the	the	DT
cord-322904-9mta0aem	45	7	initials	initial	NNS
cord-322904-9mta0aem	45	8	of	of	IN
cord-322904-9mta0aem	45	9	the	the	DT
cord-322904-9mta0aem	45	10	patient	patient	NN
cord-322904-9mta0aem	45	11	from	from	IN
cord-322904-9mta0aem	45	12	whom	whom	WP
cord-322904-9mta0aem	45	13	it	-PRON-	PRP
cord-322904-9mta0aem	45	14	was	be	VBD
cord-322904-9mta0aem	45	15	isolated	isolate	VBN
cord-322904-9mta0aem	45	16	.	.	.
cord-322904-9mta0aem	46	1	The	the	DT
cord-322904-9mta0aem	46	2	first	first	JJ
cord-322904-9mta0aem	46	3	studies	study	NNS
cord-322904-9mta0aem	46	4	of	of	IN
cord-322904-9mta0aem	46	5	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	46	6	host	host	NN
cord-322904-9mta0aem	46	7	-	-	HYPH
cord-322904-9mta0aem	46	8	cell	cell	NN
cord-322904-9mta0aem	46	9	interactions	interaction	NNS
cord-322904-9mta0aem	46	10	followed	follow	VBD
cord-322904-9mta0aem	46	11	closely	closely	RB
cord-322904-9mta0aem	46	12	behind	behind	IN
cord-322904-9mta0aem	46	13	their	-PRON-	PRP$
cord-322904-9mta0aem	46	14	initial	initial	JJ
cord-322904-9mta0aem	46	15	discovery	discovery	NN
cord-322904-9mta0aem	46	16	and	and	CC
cord-322904-9mta0aem	46	17	isolation	isolation	NN
cord-322904-9mta0aem	46	18	in	in	IN
cord-322904-9mta0aem	46	19	mammalian	mammalian	JJ
cord-322904-9mta0aem	46	20	tissue	tissue	NN
cord-322904-9mta0aem	46	21	culture	culture	NN
cord-322904-9mta0aem	46	22	.	.	.
cord-322904-9mta0aem	47	1	Shortly	shortly	RB
cord-322904-9mta0aem	47	2	after	after	IN
cord-322904-9mta0aem	47	3	virus	virus	NN
cord-322904-9mta0aem	47	4	cultivation	cultivation	NN
cord-322904-9mta0aem	47	5	a	a	DT
cord-322904-9mta0aem	47	6	number	number	NN
cord-322904-9mta0aem	47	7	of	of	IN
cord-322904-9mta0aem	47	8	groups	group	NNS
cord-322904-9mta0aem	47	9	began	begin	VBD
cord-322904-9mta0aem	47	10	examining	examine	VBG
cord-322904-9mta0aem	47	11	the	the	DT
cord-322904-9mta0aem	47	12	interaction	interaction	NN
cord-322904-9mta0aem	47	13	of	of	IN
cord-322904-9mta0aem	47	14	mPyV	mPyV	NNP
cord-322904-9mta0aem	47	15	with	with	IN
cord-322904-9mta0aem	47	16	host	host	NN
cord-322904-9mta0aem	47	17	cells	cell	NNS
cord-322904-9mta0aem	47	18	using	use	VBG
cord-322904-9mta0aem	47	19	both	both	CC
cord-322904-9mta0aem	47	20	biochemical	biochemical	JJ
cord-322904-9mta0aem	47	21	and	and	CC
cord-322904-9mta0aem	47	22	electron	electron	NN
cord-322904-9mta0aem	47	23	microscopy	microscopy	NNS
cord-322904-9mta0aem	47	24	(	(	-LRB-
cord-322904-9mta0aem	47	25	EM	EM	NNP
cord-322904-9mta0aem	47	26	)	)	-RRB-
cord-322904-9mta0aem	47	27	techniques	technique	NNS
cord-322904-9mta0aem	47	28	.	.	.
cord-322904-9mta0aem	48	1	Infection	infection	NN
cord-322904-9mta0aem	48	2	of	of	IN
cord-322904-9mta0aem	48	3	cells	cell	NNS
cord-322904-9mta0aem	48	4	by	by	IN
cord-322904-9mta0aem	48	5	the	the	DT
cord-322904-9mta0aem	48	6	mPyV	mpyv	NN
cord-322904-9mta0aem	48	7	was	be	VBD
cord-322904-9mta0aem	48	8	envisioned	envision	VBN
cord-322904-9mta0aem	48	9	as	as	IN
cord-322904-9mta0aem	48	10	a	a	DT
cord-322904-9mta0aem	48	11	multi	multi	JJ
cord-322904-9mta0aem	48	12	-	-	JJ
cord-322904-9mta0aem	48	13	step	step	JJ
cord-322904-9mta0aem	48	14	process	process	NN
cord-322904-9mta0aem	48	15	that	that	WDT
cord-322904-9mta0aem	48	16	included	include	VBD
cord-322904-9mta0aem	48	17	virus	virus	NN
cord-322904-9mta0aem	48	18	adsorption	adsorption	NN
cord-322904-9mta0aem	48	19	,	,	,
cord-322904-9mta0aem	48	20	virus	virus	NN
cord-322904-9mta0aem	48	21	penetration	penetration	NN
cord-322904-9mta0aem	48	22	,	,	,
cord-322904-9mta0aem	48	23	and	and	CC
cord-322904-9mta0aem	48	24	virus	virus	NN
cord-322904-9mta0aem	48	25	uncoating	uncoating	NN
cord-322904-9mta0aem	48	26	.	.	.
cord-322904-9mta0aem	49	1	Morphological	morphological	JJ
cord-322904-9mta0aem	49	2	studies	study	NNS
cord-322904-9mta0aem	49	3	documented	document	VBD
cord-322904-9mta0aem	49	4	that	that	IN
cord-322904-9mta0aem	49	5	whole	whole	JJ
cord-322904-9mta0aem	49	6	virions	virion	NNS
cord-322904-9mta0aem	49	7	were	be	VBD
cord-322904-9mta0aem	49	8	taken	take	VBN
cord-322904-9mta0aem	49	9	up	up	RP
cord-322904-9mta0aem	49	10	into	into	IN
cord-322904-9mta0aem	49	11	cells	cell	NNS
cord-322904-9mta0aem	49	12	by	by	IN
cord-322904-9mta0aem	49	13	phagocytosis	phagocytosis	NN
cord-322904-9mta0aem	49	14	as	as	IN
cord-322904-9mta0aem	49	15	membrane	membrane	NN
cord-322904-9mta0aem	49	16	bound	bind	VBD
cord-322904-9mta0aem	49	17	single	single	JJ
cord-322904-9mta0aem	49	18	particles	particle	NNS
cord-322904-9mta0aem	49	19	and	and	CC
cord-322904-9mta0aem	49	20	membrane	membrane	NN
cord-322904-9mta0aem	49	21	bound	bind	VBN
cord-322904-9mta0aem	49	22	aggregates	aggregate	NNS
cord-322904-9mta0aem	50	1	(	(	-LRB-
cord-322904-9mta0aem	50	2	Mattern	Mattern	NNP
cord-322904-9mta0aem	50	3	et	et	NNP
cord-322904-9mta0aem	50	4	al	al	NNP
cord-322904-9mta0aem	50	5	.	.	NNP
cord-322904-9mta0aem	50	6	,	,	,
cord-322904-9mta0aem	50	7	1966	1966	CD
cord-322904-9mta0aem	50	8	;	;	:
cord-322904-9mta0aem	50	9	Mattern	Mattern	NNP
cord-322904-9mta0aem	50	10	et	et	NNP
cord-322904-9mta0aem	50	11	al	al	NNP
cord-322904-9mta0aem	50	12	.	.	NNP
cord-322904-9mta0aem	50	13	,	,	,
cord-322904-9mta0aem	50	14	1967	1967	CD
cord-322904-9mta0aem	50	15	)	)	-RRB-
cord-322904-9mta0aem	50	16	.	.	.
cord-322904-9mta0aem	51	1	Virus	virus	NN
cord-322904-9mta0aem	51	2	particles	particle	NNS
cord-322904-9mta0aem	51	3	then	then	RB
cord-322904-9mta0aem	51	4	appeared	appear	VBD
cord-322904-9mta0aem	51	5	between	between	IN
cord-322904-9mta0aem	51	6	the	the	DT
cord-322904-9mta0aem	51	7	nuclear	nuclear	JJ
cord-322904-9mta0aem	51	8	membrane	membrane	NN
cord-322904-9mta0aem	51	9	but	but	CC
cord-322904-9mta0aem	51	10	viral	viral	JJ
cord-322904-9mta0aem	51	11	particles	particle	NNS
cord-322904-9mta0aem	51	12	were	be	VBD
cord-322904-9mta0aem	51	13	not	not	RB
cord-322904-9mta0aem	51	14	seen	see	VBN
cord-322904-9mta0aem	51	15	within	within	IN
cord-322904-9mta0aem	51	16	the	the	DT
cord-322904-9mta0aem	51	17	nucleus	nucleus	NN
cord-322904-9mta0aem	51	18	at	at	IN
cord-322904-9mta0aem	51	19	these	these	DT
cord-322904-9mta0aem	51	20	early	early	JJ
cord-322904-9mta0aem	51	21	times	time	NNS
cord-322904-9mta0aem	51	22	.	.	.
cord-322904-9mta0aem	52	1	This	this	DT
cord-322904-9mta0aem	52	2	led	lead	VBD
cord-322904-9mta0aem	52	3	to	to	IN
cord-322904-9mta0aem	52	4	the	the	DT
cord-322904-9mta0aem	52	5	conclusion	conclusion	NN
cord-322904-9mta0aem	52	6	that	that	IN
cord-322904-9mta0aem	52	7	viral	viral	JJ
cord-322904-9mta0aem	52	8	particles	particle	NNS
cord-322904-9mta0aem	52	9	uncoat	uncoat	RB
cord-322904-9mta0aem	52	10	between	between	IN
cord-322904-9mta0aem	52	11	the	the	DT
cord-322904-9mta0aem	52	12	nuclear	nuclear	JJ
cord-322904-9mta0aem	52	13	membranes	membrane	NNS
cord-322904-9mta0aem	52	14	and	and	CC
cord-322904-9mta0aem	52	15	before	before	IN
cord-322904-9mta0aem	52	16	they	-PRON-	PRP
cord-322904-9mta0aem	52	17	reach	reach	VBP
cord-322904-9mta0aem	52	18	the	the	DT
cord-322904-9mta0aem	52	19	nucleus	nucleus	NN
cord-322904-9mta0aem	52	20	(	(	-LRB-
cord-322904-9mta0aem	52	21	as	as	IN
cord-322904-9mta0aem	52	22	we	-PRON-	PRP
cord-322904-9mta0aem	52	23	will	will	MD
cord-322904-9mta0aem	52	24	see	see	VB
cord-322904-9mta0aem	52	25	later	later	RB
cord-322904-9mta0aem	52	26	this	this	DT
cord-322904-9mta0aem	52	27	interpretation	interpretation	NN
cord-322904-9mta0aem	52	28	is	be	VBZ
cord-322904-9mta0aem	52	29	largely	largely	RB
cord-322904-9mta0aem	52	30	correct	correct	JJ
cord-322904-9mta0aem	52	31	with	with	IN
cord-322904-9mta0aem	52	32	some	some	DT
cord-322904-9mta0aem	52	33	minor	minor	JJ
cord-322904-9mta0aem	52	34	modifications	modification	NNS
cord-322904-9mta0aem	52	35	)	)	-RRB-
cord-322904-9mta0aem	52	36	.	.	.
cord-322904-9mta0aem	53	1	In	in	IN
cord-322904-9mta0aem	53	2	the	the	DT
cord-322904-9mta0aem	53	3	early	early	JJ
cord-322904-9mta0aem	53	4	1970s	1970	NNS
cord-322904-9mta0aem	53	5	it	-PRON-	PRP
cord-322904-9mta0aem	53	6	became	become	VBD
cord-322904-9mta0aem	53	7	apparent	apparent	JJ
cord-322904-9mta0aem	53	8	that	that	IN
cord-322904-9mta0aem	53	9	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	53	10	preparations	preparation	NNS
cord-322904-9mta0aem	53	11	contained	contain	VBD
cord-322904-9mta0aem	53	12	significant	significant	JJ
cord-322904-9mta0aem	53	13	numbers	number	NNS
cord-322904-9mta0aem	53	14	of	of	IN
cord-322904-9mta0aem	53	15	defective	defective	JJ
cord-322904-9mta0aem	53	16	interfering	interfere	VBG
cord-322904-9mta0aem	53	17	particles	particle	NNS
cord-322904-9mta0aem	53	18	.	.	.
cord-322904-9mta0aem	54	1	The	the	DT
cord-322904-9mta0aem	54	2	ability	ability	NN
cord-322904-9mta0aem	54	3	to	to	TO
cord-322904-9mta0aem	54	4	plaque	plaque	NN
cord-322904-9mta0aem	54	5	purify	purify	VB
cord-322904-9mta0aem	54	6	virus	virus	NN
cord-322904-9mta0aem	54	7	preparations	preparation	NNS
cord-322904-9mta0aem	54	8	allowed	allow	VBN
cord-322904-9mta0aem	54	9	for	for	IN
cord-322904-9mta0aem	54	10	an	an	DT
cord-322904-9mta0aem	54	11	enrichment	enrichment	NN
cord-322904-9mta0aem	54	12	of	of	IN
cord-322904-9mta0aem	54	13	infectious	infectious	JJ
cord-322904-9mta0aem	54	14	virions	virion	NNS
cord-322904-9mta0aem	54	15	and	and	CC
cord-322904-9mta0aem	54	16	for	for	IN
cord-322904-9mta0aem	54	17	their	-PRON-	PRP$
cord-322904-9mta0aem	54	18	separation	separation	NN
cord-322904-9mta0aem	54	19	from	from	IN
cord-322904-9mta0aem	54	20	empty	empty	JJ
cord-322904-9mta0aem	54	21	capsids	capsid	NNS
cord-322904-9mta0aem	54	22	by	by	IN
cord-322904-9mta0aem	54	23	density	density	NN
cord-322904-9mta0aem	54	24	gradient	gradient	NN
cord-322904-9mta0aem	54	25	centrifugation	centrifugation	NN
cord-322904-9mta0aem	54	26	.	.	.
cord-322904-9mta0aem	55	1	Detailed	detailed	JJ
cord-322904-9mta0aem	55	2	analyses	analysis	NNS
cord-322904-9mta0aem	55	3	of	of	IN
cord-322904-9mta0aem	55	4	these	these	DT
cord-322904-9mta0aem	55	5	individual	individual	JJ
cord-322904-9mta0aem	55	6	populations	population	NNS
cord-322904-9mta0aem	55	7	by	by	IN
cord-322904-9mta0aem	55	8	EM	EM	NNP
cord-322904-9mta0aem	55	9	indicated	indicate	VBD
cord-322904-9mta0aem	55	10	that	that	IN
cord-322904-9mta0aem	55	11	empty	empty	JJ
cord-322904-9mta0aem	55	12	capsids	capsid	NNS
cord-322904-9mta0aem	55	13	and	and	CC
cord-322904-9mta0aem	55	14	light	light	JJ
cord-322904-9mta0aem	55	15	populations	population	NNS
cord-322904-9mta0aem	55	16	of	of	IN
cord-322904-9mta0aem	55	17	virions	virion	NNS
cord-322904-9mta0aem	55	18	(	(	-LRB-
cord-322904-9mta0aem	55	19	pseudovirions	pseudovirion	NNS
cord-322904-9mta0aem	55	20	)	)	-RRB-
cord-322904-9mta0aem	55	21	were	be	VBD
cord-322904-9mta0aem	55	22	endocytosed	endocytose	VBN
cord-322904-9mta0aem	55	23	by	by	IN
cord-322904-9mta0aem	55	24	two	two	CD
cord-322904-9mta0aem	55	25	different	different	JJ
cord-322904-9mta0aem	55	26	pathways	pathway	NNS
cord-322904-9mta0aem	55	27	(	(	-LRB-
cord-322904-9mta0aem	55	28	Bolen	Bolen	NNP
cord-322904-9mta0aem	55	29	and	and	CC
cord-322904-9mta0aem	55	30	Consigli	Consigli	NNP
cord-322904-9mta0aem	55	31	,	,	,
cord-322904-9mta0aem	55	32	1979	1979	CD
cord-322904-9mta0aem	55	33	;	;	:
cord-322904-9mta0aem	55	34	Mackay	Mackay	NNP
cord-322904-9mta0aem	55	35	and	and	CC
cord-322904-9mta0aem	55	36	Consigli	Consigli	NNP
cord-322904-9mta0aem	55	37	,	,	,
cord-322904-9mta0aem	55	38	1976	1976	CD
cord-322904-9mta0aem	55	39	)	)	-RRB-
cord-322904-9mta0aem	55	40	.	.	.
cord-322904-9mta0aem	56	1	Virions	virion	NNS
cord-322904-9mta0aem	56	2	and	and	CC
cord-322904-9mta0aem	56	3	pseudovirions	pseudovirion	NNS
cord-322904-9mta0aem	56	4	were	be	VBD
cord-322904-9mta0aem	56	5	predominantly	predominantly	RB
cord-322904-9mta0aem	56	6	endocytosed	endocytose	VBN
cord-322904-9mta0aem	56	7	as	as	IN
cord-322904-9mta0aem	56	8	single	single	JJ
cord-322904-9mta0aem	56	9	membrane	membrane	NN
cord-322904-9mta0aem	56	10	-	-	HYPH
cord-322904-9mta0aem	56	11	bound	bind	VBN
cord-322904-9mta0aem	56	12	particles	particle	NNS
cord-322904-9mta0aem	56	13	that	that	WDT
cord-322904-9mta0aem	56	14	trafficked	traffic	VBD
cord-322904-9mta0aem	56	15	intact	intact	JJ
cord-322904-9mta0aem	56	16	to	to	IN
cord-322904-9mta0aem	56	17	the	the	DT
cord-322904-9mta0aem	56	18	nucleus	nucleus	NN
cord-322904-9mta0aem	56	19	.	.	.
cord-322904-9mta0aem	57	1	Empty	empty	JJ
cord-322904-9mta0aem	57	2	capsids	capsid	NNS
cord-322904-9mta0aem	57	3	were	be	VBD
cord-322904-9mta0aem	57	4	endocytosed	endocytose	VBN
cord-322904-9mta0aem	57	5	as	as	IN
cord-322904-9mta0aem	57	6	aggregates	aggregate	NNS
cord-322904-9mta0aem	57	7	into	into	IN
cord-322904-9mta0aem	57	8	large	large	JJ
cord-322904-9mta0aem	57	9	vesicles	vesicle	NNS
cord-322904-9mta0aem	57	10	that	that	WDT
cord-322904-9mta0aem	57	11	later	later	RB
cord-322904-9mta0aem	57	12	appeared	appear	VBD
cord-322904-9mta0aem	57	13	to	to	TO
cord-322904-9mta0aem	57	14	fuse	fuse	VB
cord-322904-9mta0aem	57	15	with	with	IN
cord-322904-9mta0aem	57	16	lysosomes	lysosome	NNS
cord-322904-9mta0aem	57	17	,	,	,
cord-322904-9mta0aem	57	18	apparently	apparently	RB
cord-322904-9mta0aem	57	19	destined	destine	VBN
cord-322904-9mta0aem	57	20	for	for	IN
cord-322904-9mta0aem	57	21	degradation	degradation	NN
cord-322904-9mta0aem	57	22	.	.	.
cord-322904-9mta0aem	58	1	A	a	DT
cord-322904-9mta0aem	58	2	model	model	NN
cord-322904-9mta0aem	58	3	was	be	VBD
cord-322904-9mta0aem	58	4	developed	develop	VBN
cord-322904-9mta0aem	58	5	showing	show	VBG
cord-322904-9mta0aem	58	6	these	these	DT
cord-322904-9mta0aem	58	7	two	two	CD
cord-322904-9mta0aem	58	8	opposing	oppose	VBG
cord-322904-9mta0aem	58	9	endocytic	endocytic	JJ
cord-322904-9mta0aem	58	10	routes	route	NNS
cord-322904-9mta0aem	58	11	in	in	IN
cord-322904-9mta0aem	58	12	the	the	DT
cord-322904-9mta0aem	58	13	cell	cell	NN
cord-322904-9mta0aem	58	14	(	(	-LRB-
cord-322904-9mta0aem	58	15	Fig	Fig	NNP
cord-322904-9mta0aem	58	16	.	.	.
cord-322904-9mta0aem	58	17	1	1	CD
cord-322904-9mta0aem	58	18	)	)	-RRB-
cord-322904-9mta0aem	58	19	.	.	.
cord-322904-9mta0aem	59	1	The	the	DT
cord-322904-9mta0aem	59	2	fact	fact	NN
cord-322904-9mta0aem	59	3	that	that	IN
cord-322904-9mta0aem	59	4	virions	virion	NNS
cord-322904-9mta0aem	59	5	and	and	CC
cord-322904-9mta0aem	59	6	pseudovirions	pseudovirion	NNS
cord-322904-9mta0aem	59	7	behaved	behave	VBD
cord-322904-9mta0aem	59	8	differently	differently	RB
cord-322904-9mta0aem	59	9	than	than	IN
cord-322904-9mta0aem	59	10	empty	empty	JJ
cord-322904-9mta0aem	59	11	capsids	capsid	NNS
cord-322904-9mta0aem	59	12	led	lead	VBD
cord-322904-9mta0aem	59	13	Consigli	Consigli	NNP
cord-322904-9mta0aem	59	14	and	and	CC
cord-322904-9mta0aem	59	15	colleagues	colleague	NNS
cord-322904-9mta0aem	59	16	to	to	TO
cord-322904-9mta0aem	59	17	carefully	carefully	RB
cord-322904-9mta0aem	59	18	examine	examine	VB
cord-322904-9mta0aem	59	19	the	the	DT
cord-322904-9mta0aem	59	20	viral	viral	JJ
cord-322904-9mta0aem	59	21	particles	particle	NNS
cord-322904-9mta0aem	59	22	for	for	IN
cord-322904-9mta0aem	59	23	subtle	subtle	JJ
cord-322904-9mta0aem	59	24	differences	difference	NNS
cord-322904-9mta0aem	59	25	in	in	IN
cord-322904-9mta0aem	59	26	protein	protein	NN
cord-322904-9mta0aem	59	27	composition	composition	NN
cord-322904-9mta0aem	59	28	.	.	.
cord-322904-9mta0aem	60	1	Using	use	VBG
cord-322904-9mta0aem	60	2	radiolabeled	radiolabele	VBN
cord-322904-9mta0aem	60	3	preparations	preparation	NNS
cord-322904-9mta0aem	60	4	they	-PRON-	PRP
cord-322904-9mta0aem	60	5	identified	identify	VBD
cord-322904-9mta0aem	60	6	six	six	CD
cord-322904-9mta0aem	60	7	species	specie	NNS
cord-322904-9mta0aem	60	8	of	of	IN
cord-322904-9mta0aem	60	9	VP1	VP1	NNP
cord-322904-9mta0aem	60	10	(	(	-LRB-
cord-322904-9mta0aem	60	11	A	A	NNP
cord-322904-9mta0aem	60	12	-	-	HYPH
cord-322904-9mta0aem	60	13	F	F	NNP
cord-322904-9mta0aem	60	14	)	)	-RRB-
cord-322904-9mta0aem	60	15	by	by	IN
cord-322904-9mta0aem	60	16	isolelectric	isolelectric	NNP
cord-322904-9mta0aem	60	17	focusing	focus	VBG
cord-322904-9mta0aem	61	1	(	(	-LRB-
cord-322904-9mta0aem	61	2	Bolen	Bolen	NNP
cord-322904-9mta0aem	61	3	et	et	NNP
cord-322904-9mta0aem	61	4	al	al	NNP
cord-322904-9mta0aem	61	5	.	.	NNP
cord-322904-9mta0aem	61	6	,	,	,
cord-322904-9mta0aem	61	7	1981	1981	CD
cord-322904-9mta0aem	61	8	)	)	-RRB-
cord-322904-9mta0aem	61	9	.	.	.
cord-322904-9mta0aem	62	1	Only	only	JJ
cord-322904-9mta0aem	62	2	virions	virion	NNS
cord-322904-9mta0aem	62	3	and	and	CC
cord-322904-9mta0aem	62	4	pseudovirions	pseudovirion	NNS
cord-322904-9mta0aem	62	5	were	be	VBD
cord-322904-9mta0aem	62	6	found	find	VBN
cord-322904-9mta0aem	62	7	to	to	TO
cord-322904-9mta0aem	62	8	contain	contain	VB
cord-322904-9mta0aem	62	9	species	specie	NNS
cord-322904-9mta0aem	62	10	E	e	NN
cord-322904-9mta0aem	62	11	leading	lead	VBG
cord-322904-9mta0aem	62	12	the	the	DT
cord-322904-9mta0aem	62	13	group	group	NN
cord-322904-9mta0aem	62	14	to	to	TO
cord-322904-9mta0aem	62	15	hypothesize	hypothesize	VB
cord-322904-9mta0aem	62	16	that	that	IN
cord-322904-9mta0aem	62	17	species	species	NN
cord-322904-9mta0aem	62	18	E	E	NNP
cord-322904-9mta0aem	62	19	was	be	VBD
cord-322904-9mta0aem	62	20	critical	critical	JJ
cord-322904-9mta0aem	62	21	for	for	IN
cord-322904-9mta0aem	62	22	delivering	deliver	VBG
cord-322904-9mta0aem	62	23	virions	virion	NNS
cord-322904-9mta0aem	62	24	and	and	CC
cord-322904-9mta0aem	62	25	pseudovirions	pseudovirion	NNS
cord-322904-9mta0aem	62	26	to	to	IN
cord-322904-9mta0aem	62	27	the	the	DT
cord-322904-9mta0aem	62	28	nucleus	nucleus	NN
cord-322904-9mta0aem	62	29	.	.	.
cord-322904-9mta0aem	63	1	Antibodies	antibody	NNS
cord-322904-9mta0aem	63	2	raised	raise	VBD
cord-322904-9mta0aem	63	3	against	against	IN
cord-322904-9mta0aem	63	4	virions	virion	NNS
cord-322904-9mta0aem	63	5	that	that	WDT
cord-322904-9mta0aem	63	6	were	be	VBD
cord-322904-9mta0aem	63	7	found	find	VBN
cord-322904-9mta0aem	63	8	to	to	TO
cord-322904-9mta0aem	63	9	be	be	VB
cord-322904-9mta0aem	63	10	neutralizing	neutralize	VBG
cord-322904-9mta0aem	63	11	specifically	specifically	RB
cord-322904-9mta0aem	63	12	recognized	recognize	VBN
cord-322904-9mta0aem	63	13	species	specie	NNS
cord-322904-9mta0aem	63	14	D	d	NN
cord-322904-9mta0aem	63	15	,	,	,
cord-322904-9mta0aem	63	16	E	E	NNP
cord-322904-9mta0aem	63	17	,	,	,
cord-322904-9mta0aem	63	18	and	and	CC
cord-322904-9mta0aem	63	19	F	F	NNP
cord-322904-9mta0aem	63	20	supporting	support	VBG
cord-322904-9mta0aem	63	21	this	this	DT
cord-322904-9mta0aem	63	22	hypothesis	hypothesis	NN
cord-322904-9mta0aem	63	23	(	(	-LRB-
cord-322904-9mta0aem	63	24	Bolen	Bolen	NNP
cord-322904-9mta0aem	63	25	et	et	NNP
cord-322904-9mta0aem	63	26	al	al	NNP
cord-322904-9mta0aem	63	27	.	.	NNP
cord-322904-9mta0aem	63	28	,	,	,
cord-322904-9mta0aem	63	29	1981	1981	CD
cord-322904-9mta0aem	63	30	)	)	-RRB-
cord-322904-9mta0aem	63	31	.	.	.
cord-322904-9mta0aem	64	1	The	the	DT
cord-322904-9mta0aem	64	2	group	group	NN
cord-322904-9mta0aem	64	3	then	then	RB
cord-322904-9mta0aem	64	4	went	go	VBD
cord-322904-9mta0aem	64	5	on	on	RP
cord-322904-9mta0aem	64	6	to	to	TO
cord-322904-9mta0aem	64	7	attempt	attempt	VB
cord-322904-9mta0aem	64	8	isolation	isolation	NN
cord-322904-9mta0aem	64	9	of	of	IN
cord-322904-9mta0aem	64	10	cellular	cellular	JJ
cord-322904-9mta0aem	64	11	receptors	receptor	NNS
cord-322904-9mta0aem	64	12	for	for	IN
cord-322904-9mta0aem	64	13	mPyV	mPyV	NNP
cord-322904-9mta0aem	64	14	by	by	IN
cord-322904-9mta0aem	64	15	preparing	prepare	VBG
cord-322904-9mta0aem	64	16	anti	anti	JJ
cord-322904-9mta0aem	64	17	-	-	JJ
cord-322904-9mta0aem	64	18	idiotypic	idiotypic	JJ
cord-322904-9mta0aem	64	19	antibodies	antibody	NNS
cord-322904-9mta0aem	64	20	to	to	IN
cord-322904-9mta0aem	64	21	VP1	VP1	NNP
cord-322904-9mta0aem	64	22	(	(	-LRB-
cord-322904-9mta0aem	64	23	Marriott	Marriott	NNP
cord-322904-9mta0aem	64	24	and	and	CC
cord-322904-9mta0aem	64	25	Consigli	Consigli	NNP
cord-322904-9mta0aem	64	26	,	,	,
cord-322904-9mta0aem	64	27	1985	1985	CD
cord-322904-9mta0aem	64	28	;	;	:
cord-322904-9mta0aem	64	29	Marriott	Marriott	NNP
cord-322904-9mta0aem	64	30	et	et	NNP
cord-322904-9mta0aem	64	31	al	al	NNP
cord-322904-9mta0aem	64	32	.	.	NNP
cord-322904-9mta0aem	64	33	,	,	,
cord-322904-9mta0aem	64	34	1987	1987	CD
cord-322904-9mta0aem	64	35	)	)	-RRB-
cord-322904-9mta0aem	64	36	.	.	.
cord-322904-9mta0aem	65	1	These	these	DT
cord-322904-9mta0aem	65	2	antibodies	antibody	NNS
cord-322904-9mta0aem	65	3	blocked	block	VBD
cord-322904-9mta0aem	65	4	infection	infection	NN
cord-322904-9mta0aem	65	5	and	and	CC
cord-322904-9mta0aem	65	6	pulled	pull	VBD
cord-322904-9mta0aem	65	7	down	down	RP
cord-322904-9mta0aem	65	8	several	several	JJ
cord-322904-9mta0aem	65	9	proteins	protein	NNS
cord-322904-9mta0aem	65	10	associated	associate	VBN
cord-322904-9mta0aem	65	11	with	with	IN
cord-322904-9mta0aem	65	12	cell	cell	NN
cord-322904-9mta0aem	65	13	surfaces	surface	NNS
cord-322904-9mta0aem	65	14	.	.	.
cord-322904-9mta0aem	66	1	The	the	DT
cord-322904-9mta0aem	66	2	identities	identity	NNS
cord-322904-9mta0aem	66	3	of	of	IN
cord-322904-9mta0aem	66	4	these	these	DT
cord-322904-9mta0aem	66	5	proteins	protein	NNS
cord-322904-9mta0aem	66	6	were	be	VBD
cord-322904-9mta0aem	66	7	never	never	RB
cord-322904-9mta0aem	66	8	determined	determine	VBN
cord-322904-9mta0aem	66	9	and	and	CC
cord-322904-9mta0aem	66	10	none	none	NN
cord-322904-9mta0aem	66	11	were	be	VBD
cord-322904-9mta0aem	66	12	found	find	VBN
cord-322904-9mta0aem	66	13	to	to	TO
cord-322904-9mta0aem	66	14	act	act	VB
cord-322904-9mta0aem	66	15	as	as	IN
cord-322904-9mta0aem	66	16	receptors	receptor	NNS
cord-322904-9mta0aem	66	17	for	for	IN
cord-322904-9mta0aem	66	18	the	the	DT
cord-322904-9mta0aem	66	19	virus	virus	NN
cord-322904-9mta0aem	66	20	.	.	.
cord-322904-9mta0aem	67	1	The	the	DT
cord-322904-9mta0aem	67	2	mPyV	mpyv	NN
cord-322904-9mta0aem	67	3	and	and	CC
cord-322904-9mta0aem	67	4	the	the	DT
cord-322904-9mta0aem	67	5	two	two	CD
cord-322904-9mta0aem	67	6	human	human	JJ
cord-322904-9mta0aem	67	7	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	67	8	,	,	,
cord-322904-9mta0aem	67	9	JCV	JCV	NNP
cord-322904-9mta0aem	67	10	and	and	CC
cord-322904-9mta0aem	67	11	BKV	BKV	NNP
cord-322904-9mta0aem	67	12	are	be	VBP
cord-322904-9mta0aem	67	13	known	know	VBN
cord-322904-9mta0aem	67	14	to	to	TO
cord-322904-9mta0aem	67	15	require	require	VB
cord-322904-9mta0aem	67	16	sialic	sialic	JJ
cord-322904-9mta0aem	67	17	acid	acid	NN
cord-322904-9mta0aem	67	18	for	for	IN
cord-322904-9mta0aem	67	19	binding	bind	VBG
cord-322904-9mta0aem	67	20	to	to	IN
cord-322904-9mta0aem	67	21	host	host	NN
cord-322904-9mta0aem	67	22	cells	cell	NNS
cord-322904-9mta0aem	67	23	as	as	IN
cord-322904-9mta0aem	67	24	"	"	``
cord-322904-9mta0aem	67	25	receptor	receptor	NN
cord-322904-9mta0aem	67	26	destroying	destroy	VBG
cord-322904-9mta0aem	67	27	enzyme	enzyme	NN
cord-322904-9mta0aem	67	28	"	"	''
cord-322904-9mta0aem	67	29	or	or	CC
cord-322904-9mta0aem	67	30	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	67	31	inhibits	inhibit	VBZ
cord-322904-9mta0aem	67	32	the	the	DT
cord-322904-9mta0aem	67	33	viruses	virus	NNS
cord-322904-9mta0aem	67	34	'	'	POS
cord-322904-9mta0aem	67	35	ability	ability	NN
cord-322904-9mta0aem	67	36	to	to	TO
cord-322904-9mta0aem	67	37	agglutinate	agglutinate	VB
cord-322904-9mta0aem	67	38	red	red	JJ
cord-322904-9mta0aem	67	39	blood	blood	NN
cord-322904-9mta0aem	67	40	cells	cell	NNS
cord-322904-9mta0aem	67	41	and	and	CC
cord-322904-9mta0aem	67	42	to	to	TO
cord-322904-9mta0aem	67	43	infect	infect	VB
cord-322904-9mta0aem	67	44	cells	cell	NNS
cord-322904-9mta0aem	67	45	(	(	-LRB-
cord-322904-9mta0aem	67	46	Table	table	NN
cord-322904-9mta0aem	67	47	1	1	CD
cord-322904-9mta0aem	67	48	)	)	-RRB-
cord-322904-9mta0aem	67	49	.	.	.
cord-322904-9mta0aem	68	1	SV40	SV40	NNP
cord-322904-9mta0aem	68	2	was	be	VBD
cord-322904-9mta0aem	68	3	thought	think	VBN
cord-322904-9mta0aem	68	4	not	not	RB
cord-322904-9mta0aem	68	5	to	to	TO
cord-322904-9mta0aem	68	6	attach	attach	VB
cord-322904-9mta0aem	68	7	to	to	IN
cord-322904-9mta0aem	68	8	sialic	sialic	JJ
cord-322904-9mta0aem	68	9	acid	acid	NN
cord-322904-9mta0aem	68	10	as	as	IN
cord-322904-9mta0aem	68	11	it	-PRON-	PRP
cord-322904-9mta0aem	68	12	did	do	VBD
cord-322904-9mta0aem	68	13	not	not	RB
cord-322904-9mta0aem	68	14	agglutinate	agglutinate	VB
cord-322904-9mta0aem	68	15	red	red	JJ
cord-322904-9mta0aem	68	16	blood	blood	NN
cord-322904-9mta0aem	68	17	cells	cell	NNS
cord-322904-9mta0aem	68	18	and	and	CC
cord-322904-9mta0aem	68	19	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	68	20	treatment	treatment	NN
cord-322904-9mta0aem	68	21	of	of	IN
cord-322904-9mta0aem	68	22	host	host	NN
cord-322904-9mta0aem	68	23	cells	cell	NNS
cord-322904-9mta0aem	68	24	did	do	VBD
cord-322904-9mta0aem	68	25	not	not	RB
cord-322904-9mta0aem	68	26	reduce	reduce	VB
cord-322904-9mta0aem	68	27	infectivity	infectivity	NN
cord-322904-9mta0aem	68	28	(	(	-LRB-
cord-322904-9mta0aem	68	29	Clayson	Clayson	NNP
cord-322904-9mta0aem	68	30	and	and	CC
cord-322904-9mta0aem	68	31	Compans	Compans	NNP
cord-322904-9mta0aem	68	32	,	,	,
cord-322904-9mta0aem	68	33	1989	1989	CD
cord-322904-9mta0aem	68	34	)	)	-RRB-
cord-322904-9mta0aem	68	35	.	.	.
cord-322904-9mta0aem	69	1	However	however	RB
cord-322904-9mta0aem	69	2	,	,	,
cord-322904-9mta0aem	69	3	SV40	SV40	NNP
cord-322904-9mta0aem	69	4	does	do	VBZ
cord-322904-9mta0aem	69	5	attach	attach	VB
cord-322904-9mta0aem	69	6	to	to	IN
cord-322904-9mta0aem	69	7	a	a	DT
cord-322904-9mta0aem	69	8	sialic	sialic	JJ
cord-322904-9mta0aem	69	9	acid	acid	NN
cord-322904-9mta0aem	69	10	containing	contain	VBG
cord-322904-9mta0aem	69	11	receptor	receptor	NN
cord-322904-9mta0aem	69	12	,	,	,
cord-322904-9mta0aem	69	13	ganglioside	ganglioside	NNP
cord-322904-9mta0aem	69	14	GM1	GM1	NNP
cord-322904-9mta0aem	69	15	,	,	,
cord-322904-9mta0aem	69	16	with	with	IN
cord-322904-9mta0aem	69	17	sialic	sialic	JJ
cord-322904-9mta0aem	69	18	acid	acid	NN
cord-322904-9mta0aem	69	19	being	be	VBG
cord-322904-9mta0aem	69	20	the	the	DT
cord-322904-9mta0aem	69	21	major	major	JJ
cord-322904-9mta0aem	69	22	contact	contact	NN
cord-322904-9mta0aem	69	23	point	point	NN
cord-322904-9mta0aem	69	24	,	,	,
cord-322904-9mta0aem	69	25	but	but	CC
cord-322904-9mta0aem	69	26	the	the	DT
cord-322904-9mta0aem	69	27	narrow	narrow	JJ
cord-322904-9mta0aem	69	28	specificity	specificity	NN
cord-322904-9mta0aem	69	29	of	of	IN
cord-322904-9mta0aem	69	30	SV40	SV40	NNP
cord-322904-9mta0aem	69	31	for	for	IN
cord-322904-9mta0aem	69	32	GM1	GM1	NNP
cord-322904-9mta0aem	69	33	prevents	prevent	VBZ
cord-322904-9mta0aem	69	34	it	-PRON-	PRP
cord-322904-9mta0aem	69	35	from	from	IN
cord-322904-9mta0aem	69	36	binding	bind	VBG
cord-322904-9mta0aem	69	37	to	to	IN
cord-322904-9mta0aem	69	38	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	69	39	on	on	IN
cord-322904-9mta0aem	69	40	red	red	JJ
cord-322904-9mta0aem	69	41	blood	blood	NN
cord-322904-9mta0aem	69	42	cells	cell	NNS
cord-322904-9mta0aem	69	43	.	.	.
cord-322904-9mta0aem	70	1	In	in	IN
cord-322904-9mta0aem	70	2	Fig	Fig	NNP
cord-322904-9mta0aem	70	3	.	.	.
cord-322904-9mta0aem	71	1	1	1	LS
cord-322904-9mta0aem	71	2	.	.	.
cord-322904-9mta0aem	72	1	Early	early	JJ
cord-322904-9mta0aem	72	2	model	model	NN
cord-322904-9mta0aem	72	3	of	of	IN
cord-322904-9mta0aem	72	4	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	72	5	attachment	attachment	NN
cord-322904-9mta0aem	72	6	,	,	,
cord-322904-9mta0aem	72	7	penetration	penetration	NN
cord-322904-9mta0aem	72	8	,	,	,
cord-322904-9mta0aem	72	9	and	and	CC
cord-322904-9mta0aem	72	10	nuclear	nuclear	JJ
cord-322904-9mta0aem	72	11	entry	entry	NN
cord-322904-9mta0aem	72	12	.	.	.
cord-322904-9mta0aem	73	1	Open	open	JJ
cord-322904-9mta0aem	73	2	virions	virion	NNS
cord-322904-9mta0aem	73	3	represent	represent	VBP
cord-322904-9mta0aem	73	4	empty	empty	JJ
cord-322904-9mta0aem	73	5	capsids	capsid	NNS
cord-322904-9mta0aem	73	6	that	that	WDT
cord-322904-9mta0aem	73	7	are	be	VBP
cord-322904-9mta0aem	73	8	found	find	VBN
cord-322904-9mta0aem	73	9	to	to	TO
cord-322904-9mta0aem	73	10	be	be	VB
cord-322904-9mta0aem	73	11	internalized	internalize	VBN
cord-322904-9mta0aem	73	12	in	in	IN
cord-322904-9mta0aem	73	13	large	large	JJ
cord-322904-9mta0aem	73	14	endosomal	endosomal	JJ
cord-322904-9mta0aem	73	15	vesicles	vesicle	NNS
cord-322904-9mta0aem	73	16	that	that	WDT
cord-322904-9mta0aem	73	17	presumably	presumably	RB
cord-322904-9mta0aem	73	18	lead	lead	VBP
cord-322904-9mta0aem	73	19	to	to	IN
cord-322904-9mta0aem	73	20	degradation	degradation	NN
cord-322904-9mta0aem	73	21	.	.	.
cord-322904-9mta0aem	74	1	Closed	closed	JJ
cord-322904-9mta0aem	74	2	virions	virion	NNS
cord-322904-9mta0aem	74	3	represent	represent	VBP
cord-322904-9mta0aem	74	4	infectious	infectious	JJ
cord-322904-9mta0aem	74	5	particles	particle	NNS
cord-322904-9mta0aem	74	6	and	and	CC
cord-322904-9mta0aem	74	7	unlike	unlike	IN
cord-322904-9mta0aem	74	8	empty	empty	JJ
cord-322904-9mta0aem	74	9	capsids	capsid	NNS
cord-322904-9mta0aem	74	10	these	these	DT
cord-322904-9mta0aem	74	11	are	be	VBP
cord-322904-9mta0aem	74	12	internalized	internalize	VBN
cord-322904-9mta0aem	74	13	into	into	IN
cord-322904-9mta0aem	74	14	monopinocytotic	monopinocytotic	JJ
cord-322904-9mta0aem	74	15	vesicles	vesicle	NNS
cord-322904-9mta0aem	74	16	.	.	.
cord-322904-9mta0aem	75	1	Some	some	DT
cord-322904-9mta0aem	75	2	virions	virion	NNS
cord-322904-9mta0aem	75	3	were	be	VBD
cord-322904-9mta0aem	75	4	found	find	VBN
cord-322904-9mta0aem	75	5	in	in	IN
cord-322904-9mta0aem	75	6	large	large	JJ
cord-322904-9mta0aem	75	7	tubular	tubular	JJ
cord-322904-9mta0aem	75	8	structures	structure	NNS
cord-322904-9mta0aem	75	9	that	that	WDT
cord-322904-9mta0aem	75	10	likely	likely	RB
cord-322904-9mta0aem	75	11	represent	represent	VBP
cord-322904-9mta0aem	75	12	the	the	DT
cord-322904-9mta0aem	75	13	pinching	pinching	NN
cord-322904-9mta0aem	75	14	off	off	RP
cord-322904-9mta0aem	75	15	of	of	IN
cord-322904-9mta0aem	75	16	these	these	DT
cord-322904-9mta0aem	75	17	structures	structure	NNS
cord-322904-9mta0aem	75	18	from	from	IN
cord-322904-9mta0aem	75	19	caveosomes	caveosome	NNS
cord-322904-9mta0aem	75	20	described	describe	VBN
cord-322904-9mta0aem	75	21	years	year	NNS
cord-322904-9mta0aem	75	22	later	later	RB
cord-322904-9mta0aem	75	23	by	by	IN
cord-322904-9mta0aem	75	24	Helenius	Helenius	NNP
cord-322904-9mta0aem	75	25	(	(	-LRB-
cord-322904-9mta0aem	75	26	see	see	VB
cord-322904-9mta0aem	75	27	text	text	NN
cord-322904-9mta0aem	75	28	for	for	IN
cord-322904-9mta0aem	75	29	detailed	detailed	JJ
cord-322904-9mta0aem	75	30	descriptions	description	NNS
cord-322904-9mta0aem	75	31	)	)	-RRB-
cord-322904-9mta0aem	75	32	.	.	.
cord-322904-9mta0aem	76	1	Modified	modify	VBN
cord-322904-9mta0aem	76	2	from	from	IN
cord-322904-9mta0aem	76	3	information	information	NN
cord-322904-9mta0aem	76	4	in	in	IN
cord-322904-9mta0aem	76	5	Mackay	Mackay	NNP
cord-322904-9mta0aem	76	6	and	and	CC
cord-322904-9mta0aem	76	7	Consigli	Consigli	NNP
cord-322904-9mta0aem	76	8	,	,	,
cord-322904-9mta0aem	76	9	1976	1976	CD
cord-322904-9mta0aem	76	10	and	and	CC
cord-322904-9mta0aem	76	11	Maul	Maul	NNP
cord-322904-9mta0aem	76	12	et	et	FW
cord-322904-9mta0aem	76	13	al	al	NNP
cord-322904-9mta0aem	76	14	.	.	NNP
cord-322904-9mta0aem	76	15	,	,	,
cord-322904-9mta0aem	76	16	1978	1978	CD
cord-322904-9mta0aem	76	17	.	.	.
cord-322904-9mta0aem	77	1	addition	addition	NN
cord-322904-9mta0aem	77	2	,	,	,
cord-322904-9mta0aem	77	3	the	the	DT
cord-322904-9mta0aem	77	4	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	77	5	used	use	VBN
cord-322904-9mta0aem	77	6	for	for	IN
cord-322904-9mta0aem	77	7	treating	treat	VBG
cord-322904-9mta0aem	77	8	cells	cell	NNS
cord-322904-9mta0aem	77	9	before	before	IN
cord-322904-9mta0aem	77	10	challenge	challenge	NN
cord-322904-9mta0aem	77	11	with	with	IN
cord-322904-9mta0aem	77	12	SV40	SV40	NNP
cord-322904-9mta0aem	77	13	does	do	VBZ
cord-322904-9mta0aem	77	14	not	not	RB
cord-322904-9mta0aem	77	15	cleave	cleave	VB
cord-322904-9mta0aem	77	16	the	the	DT
cord-322904-9mta0aem	77	17	sialic	sialic	JJ
cord-322904-9mta0aem	77	18	acid	acid	NN
cord-322904-9mta0aem	77	19	off	off	IN
cord-322904-9mta0aem	77	20	GM1	GM1	NNP
cord-322904-9mta0aem	77	21	so	so	IN
cord-322904-9mta0aem	77	22	that	that	IN
cord-322904-9mta0aem	77	23	it	-PRON-	PRP
cord-322904-9mta0aem	77	24	leaves	leave	VBZ
cord-322904-9mta0aem	77	25	the	the	DT
cord-322904-9mta0aem	77	26	receptor	receptor	NN
cord-322904-9mta0aem	77	27	intact	intact	JJ
cord-322904-9mta0aem	78	1	(	(	-LRB-
cord-322904-9mta0aem	78	2	Miller	Miller	NNP
cord-322904-9mta0aem	78	3	-	-	HYPH
cord-322904-9mta0aem	78	4	Podraza	Podraza	NNP
cord-322904-9mta0aem	78	5	et	et	NNP
cord-322904-9mta0aem	78	6	al	al	NNP
cord-322904-9mta0aem	78	7	.	.	NNP
cord-322904-9mta0aem	78	8	,	,	,
cord-322904-9mta0aem	78	9	1982	1982	CD
cord-322904-9mta0aem	78	10	)	)	-RRB-
cord-322904-9mta0aem	78	11	.	.	.
cord-322904-9mta0aem	79	1	It	-PRON-	PRP
cord-322904-9mta0aem	79	2	can	can	MD
cord-322904-9mta0aem	79	3	even	even	RB
cord-322904-9mta0aem	79	4	cleave	cleave	VB
cord-322904-9mta0aem	79	5	sialic	sialic	NN
cord-322904-9mta0aem	79	6	acid	acid	NN
cord-322904-9mta0aem	79	7	off	off	IN
cord-322904-9mta0aem	79	8	higher	high	JJR
cord-322904-9mta0aem	79	9	order	order	NN
cord-322904-9mta0aem	79	10	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	79	11	to	to	TO
cord-322904-9mta0aem	79	12	yield	yield	VB
cord-322904-9mta0aem	79	13	GM1	GM1	NNP
cord-322904-9mta0aem	79	14	.	.	.
cord-322904-9mta0aem	80	1	Therefore	therefore	RB
cord-322904-9mta0aem	80	2	,	,	,
cord-322904-9mta0aem	80	3	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	80	4	treatment	treatment	NN
cord-322904-9mta0aem	80	5	did	do	VBD
cord-322904-9mta0aem	80	6	not	not	RB
cord-322904-9mta0aem	80	7	reduce	reduce	VB
cord-322904-9mta0aem	80	8	SV40	SV40	NNP
cord-322904-9mta0aem	80	9	receptors	receptor	NNS
cord-322904-9mta0aem	80	10	on	on	IN
cord-322904-9mta0aem	80	11	cells	cell	NNS
cord-322904-9mta0aem	80	12	and	and	CC
cord-322904-9mta0aem	80	13	did	do	VBD
cord-322904-9mta0aem	80	14	not	not	RB
cord-322904-9mta0aem	80	15	abolish	abolish	VB
cord-322904-9mta0aem	80	16	infectivity	infectivity	NN
cord-322904-9mta0aem	80	17	.	.	.
cord-322904-9mta0aem	81	1	Early	early	JJ
cord-322904-9mta0aem	81	2	reports	report	NNS
cord-322904-9mta0aem	81	3	in	in	IN
cord-322904-9mta0aem	81	4	the	the	DT
cord-322904-9mta0aem	81	5	mPyV	mpyv	NN
cord-322904-9mta0aem	81	6	system	system	NN
cord-322904-9mta0aem	81	7	suggested	suggest	VBD
cord-322904-9mta0aem	81	8	that	that	IN
cord-322904-9mta0aem	81	9	the	the	DT
cord-322904-9mta0aem	81	10	sialic	sialic	JJ
cord-322904-9mta0aem	81	11	acid	acid	NN
cord-322904-9mta0aem	81	12	interactions	interaction	NNS
cord-322904-9mta0aem	81	13	were	be	VBD
cord-322904-9mta0aem	81	14	largely	largely	RB
cord-322904-9mta0aem	81	15	due	due	JJ
cord-322904-9mta0aem	81	16	to	to	IN
cord-322904-9mta0aem	81	17	non	non	JJ
cord-322904-9mta0aem	81	18	-	-	JJ
cord-322904-9mta0aem	81	19	specific	specific	JJ
cord-322904-9mta0aem	81	20	electrostatic	electrostatic	JJ
cord-322904-9mta0aem	81	21	interactions	interaction	NNS
cord-322904-9mta0aem	81	22	between	between	IN
cord-322904-9mta0aem	81	23	the	the	DT
cord-322904-9mta0aem	81	24	virus	virus	NN
cord-322904-9mta0aem	81	25	and	and	CC
cord-322904-9mta0aem	81	26	these	these	DT
cord-322904-9mta0aem	81	27	negatively	negatively	RB
cord-322904-9mta0aem	81	28	charged	charge	VBN
cord-322904-9mta0aem	81	29	cell	cell	NN
cord-322904-9mta0aem	81	30	surface	surface	NN
cord-322904-9mta0aem	81	31	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	81	32	.	.	.
cord-322904-9mta0aem	82	1	Subsequent	subsequent	JJ
cord-322904-9mta0aem	82	2	studies	study	NNS
cord-322904-9mta0aem	82	3	by	by	IN
cord-322904-9mta0aem	82	4	the	the	DT
cord-322904-9mta0aem	82	5	Paulson	Paulson	NNP
cord-322904-9mta0aem	82	6	group	group	NN
cord-322904-9mta0aem	82	7	proved	prove	VBD
cord-322904-9mta0aem	82	8	this	this	DT
cord-322904-9mta0aem	82	9	hypothesis	hypothesis	NN
cord-322904-9mta0aem	82	10	to	to	TO
cord-322904-9mta0aem	82	11	be	be	VB
cord-322904-9mta0aem	82	12	incorrect	incorrect	JJ
cord-322904-9mta0aem	82	13	(	(	-LRB-
cord-322904-9mta0aem	82	14	Cahan	Cahan	NNP
cord-322904-9mta0aem	82	15	and	and	CC
cord-322904-9mta0aem	82	16	Paulson	Paulson	NNP
cord-322904-9mta0aem	82	17	,	,	,
cord-322904-9mta0aem	82	18	1980	1980	CD
cord-322904-9mta0aem	82	19	;	;	:
cord-322904-9mta0aem	82	20	Fried	Fried	NNP
cord-322904-9mta0aem	82	21	et	et	FW
cord-322904-9mta0aem	82	22	al	al	NNP
cord-322904-9mta0aem	82	23	.	.	NNP
cord-322904-9mta0aem	82	24	,	,	,
cord-322904-9mta0aem	82	25	1981	1981	CD
cord-322904-9mta0aem	82	26	)	)	-RRB-
cord-322904-9mta0aem	82	27	.	.	.
cord-322904-9mta0aem	83	1	They	-PRON-	PRP
cord-322904-9mta0aem	83	2	showed	show	VBD
cord-322904-9mta0aem	83	3	that	that	IN
cord-322904-9mta0aem	83	4	mPyV	mPyV	NNP
cord-322904-9mta0aem	83	5	recognized	recognize	VBD
cord-322904-9mta0aem	83	6	specific	specific	JJ
cord-322904-9mta0aem	83	7	sialic	sialic	JJ
cord-322904-9mta0aem	83	8	acid	acid	NN
cord-322904-9mta0aem	83	9	structures	structure	NNS
cord-322904-9mta0aem	83	10	on	on	IN
cord-322904-9mta0aem	83	11	red	red	JJ
cord-322904-9mta0aem	83	12	blood	blood	NN
cord-322904-9mta0aem	83	13	cells	cell	NNS
cord-322904-9mta0aem	83	14	and	and	CC
cord-322904-9mta0aem	83	15	on	on	IN
cord-322904-9mta0aem	83	16	mouse	mouse	NN
cord-322904-9mta0aem	83	17	cells	cell	NNS
cord-322904-9mta0aem	83	18	containing	contain	VBG
cord-322904-9mta0aem	83	19	α2,3linked	α2,3linked	JJ
cord-322904-9mta0aem	83	20	sialic	sialic	NN
cord-322904-9mta0aem	83	21	acid	acid	NN
cord-322904-9mta0aem	83	22	.	.	.
cord-322904-9mta0aem	84	1	Small	small	JJ
cord-322904-9mta0aem	84	2	and	and	CC
cord-322904-9mta0aem	84	3	large	large	JJ
cord-322904-9mta0aem	84	4	plaque	plaque	NN
cord-322904-9mta0aem	84	5	binding	bind	VBG
cord-322904-9mta0aem	84	6	variants	variant	NNS
cord-322904-9mta0aem	84	7	of	of	IN
cord-322904-9mta0aem	84	8	mouse	mouse	NN
cord-322904-9mta0aem	84	9	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	84	10	were	be	VBD
cord-322904-9mta0aem	84	11	subsequently	subsequently	RB
cord-322904-9mta0aem	84	12	shown	show	VBN
cord-322904-9mta0aem	84	13	to	to	TO
cord-322904-9mta0aem	84	14	have	have	VB
cord-322904-9mta0aem	84	15	different	different	JJ
cord-322904-9mta0aem	84	16	affinities	affinity	NNS
cord-322904-9mta0aem	84	17	for	for	IN
cord-322904-9mta0aem	84	18	a	a	DT
cord-322904-9mta0aem	84	19	branched	branched	JJ
cord-322904-9mta0aem	84	20	compound	compound	NN
cord-322904-9mta0aem	84	21	that	that	WDT
cord-322904-9mta0aem	84	22	additionally	additionally	RB
cord-322904-9mta0aem	84	23	contained	contain	VBD
cord-322904-9mta0aem	84	24	a	a	DT
cord-322904-9mta0aem	84	25	second	second	JJ
cord-322904-9mta0aem	84	26	,	,	,
cord-322904-9mta0aem	84	27	α2,6linked	α2,6linked	JJ
cord-322904-9mta0aem	84	28	sialic	sialic	NN
cord-322904-9mta0aem	84	29	acid	acid	NN
cord-322904-9mta0aem	84	30	.	.	.
cord-322904-9mta0aem	85	1	Large	large	JJ
cord-322904-9mta0aem	85	2	plaque	plaque	NN
cord-322904-9mta0aem	85	3	strains	strain	NNS
cord-322904-9mta0aem	85	4	bound	bind	VBN
cord-322904-9mta0aem	85	5	less	less	RBR
cord-322904-9mta0aem	85	6	well	well	RB
cord-322904-9mta0aem	85	7	to	to	IN
cord-322904-9mta0aem	85	8	the	the	DT
cord-322904-9mta0aem	85	9	branched	branched	JJ
cord-322904-9mta0aem	85	10	structure	structure	NN
cord-322904-9mta0aem	85	11	than	than	IN
cord-322904-9mta0aem	85	12	did	do	VBD
cord-322904-9mta0aem	85	13	the	the	DT
cord-322904-9mta0aem	85	14	small	small	JJ
cord-322904-9mta0aem	85	15	plaque	plaque	NN
cord-322904-9mta0aem	85	16	strain	strain	NN
cord-322904-9mta0aem	85	17	(	(	-LRB-
cord-322904-9mta0aem	85	18	Cahan	Cahan	NNP
cord-322904-9mta0aem	85	19	et	et	NNP
cord-322904-9mta0aem	85	20	al	al	NNP
cord-322904-9mta0aem	85	21	.	.	NNP
cord-322904-9mta0aem	85	22	,	,	,
cord-322904-9mta0aem	85	23	1983	1983	CD
cord-322904-9mta0aem	85	24	)	)	-RRB-
cord-322904-9mta0aem	85	25	.	.	.
cord-322904-9mta0aem	86	1	These	these	DT
cord-322904-9mta0aem	86	2	data	datum	NNS
cord-322904-9mta0aem	86	3	correlated	correlate	VBD
cord-322904-9mta0aem	86	4	well	well	RB
cord-322904-9mta0aem	86	5	with	with	IN
cord-322904-9mta0aem	86	6	an	an	DT
cord-322904-9mta0aem	86	7	earlier	early	JJR
cord-322904-9mta0aem	86	8	study	study	NN
cord-322904-9mta0aem	86	9	showing	show	VBG
cord-322904-9mta0aem	86	10	that	that	DT
cord-322904-9mta0aem	86	11	small	small	JJ
cord-322904-9mta0aem	86	12	plaque	plaque	NN
cord-322904-9mta0aem	86	13	viruses	virus	NNS
cord-322904-9mta0aem	86	14	adsorb	adsorb	VBP
cord-322904-9mta0aem	86	15	to	to	TO
cord-322904-9mta0aem	86	16	cells	cell	NNS
cord-322904-9mta0aem	86	17	much	much	RB
cord-322904-9mta0aem	86	18	better	well	JJR
cord-322904-9mta0aem	86	19	than	than	IN
cord-322904-9mta0aem	86	20	the	the	DT
cord-322904-9mta0aem	86	21	large	large	JJ
cord-322904-9mta0aem	86	22	plaque	plaque	NN
cord-322904-9mta0aem	86	23	strains	strain	NNS
cord-322904-9mta0aem	86	24	(	(	-LRB-
cord-322904-9mta0aem	86	25	Diamond	Diamond	NNP
cord-322904-9mta0aem	86	26	and	and	CC
cord-322904-9mta0aem	86	27	Crawford	Crawford	NNP
cord-322904-9mta0aem	86	28	,	,	,
cord-322904-9mta0aem	86	29	1964	1964	CD
cord-322904-9mta0aem	86	30	)	)	-RRB-
cord-322904-9mta0aem	86	31	.	.	.
cord-322904-9mta0aem	87	1	In	in	IN
cord-322904-9mta0aem	87	2	more	more	JJR
cord-322904-9mta0aem	87	3	recent	recent	JJ
cord-322904-9mta0aem	87	4	studies	study	NNS
cord-322904-9mta0aem	87	5	from	from	IN
cord-322904-9mta0aem	87	6	the	the	DT
cord-322904-9mta0aem	87	7	Benjamin	Benjamin	NNP
cord-322904-9mta0aem	87	8	lab	lab	NN
cord-322904-9mta0aem	87	9	these	these	DT
cord-322904-9mta0aem	87	10	differences	difference	NNS
cord-322904-9mta0aem	87	11	were	be	VBD
cord-322904-9mta0aem	87	12	exploited	exploit	VBN
cord-322904-9mta0aem	87	13	and	and	CC
cord-322904-9mta0aem	87	14	the	the	DT
cord-322904-9mta0aem	87	15	plaque	plaque	NN
cord-322904-9mta0aem	87	16	phenotypes	phenotype	NNS
cord-322904-9mta0aem	87	17	genetically	genetically	RB
cord-322904-9mta0aem	87	18	mapped	map	VBN
cord-322904-9mta0aem	87	19	to	to	IN
cord-322904-9mta0aem	87	20	a	a	DT
cord-322904-9mta0aem	87	21	single	single	JJ
cord-322904-9mta0aem	87	22	amino	amino	NN
cord-322904-9mta0aem	87	23	acid	acid	NN
cord-322904-9mta0aem	87	24	difference	difference	NN
cord-322904-9mta0aem	87	25	in	in	IN
cord-322904-9mta0aem	87	26	the	the	DT
cord-322904-9mta0aem	87	27	major	major	JJ
cord-322904-9mta0aem	87	28	capsid	capsid	NN
cord-322904-9mta0aem	87	29	protein	protein	NN
cord-322904-9mta0aem	87	30	of	of	IN
cord-322904-9mta0aem	87	31	the	the	DT
cord-322904-9mta0aem	87	32	virus	virus	NN
cord-322904-9mta0aem	88	1	(	(	-LRB-
cord-322904-9mta0aem	88	2	Freund	Freund	NNP
cord-322904-9mta0aem	88	3	et	et	NNP
cord-322904-9mta0aem	88	4	al	al	NNP
cord-322904-9mta0aem	88	5	.	.	NNP
cord-322904-9mta0aem	88	6	,	,	,
cord-322904-9mta0aem	88	7	1991b	1991b	CD
cord-322904-9mta0aem	88	8	)	)	-RRB-
cord-322904-9mta0aem	88	9	.	.	.
cord-322904-9mta0aem	89	1	More	more	RBR
cord-322904-9mta0aem	89	2	importantly	importantly	RB
cord-322904-9mta0aem	89	3	these	these	DT
cord-322904-9mta0aem	89	4	differences	difference	NNS
cord-322904-9mta0aem	89	5	in	in	IN
cord-322904-9mta0aem	89	6	plaque	plaque	NN
cord-322904-9mta0aem	89	7	behavior	behavior	NN
cord-322904-9mta0aem	89	8	directly	directly	RB
cord-322904-9mta0aem	89	9	translated	translate	VBN
cord-322904-9mta0aem	89	10	to	to	IN
cord-322904-9mta0aem	89	11	their	-PRON-	PRP$
cord-322904-9mta0aem	89	12	behavior	behavior	NN
cord-322904-9mta0aem	89	13	in	in	IN
cord-322904-9mta0aem	89	14	mouse	mouse	NN
cord-322904-9mta0aem	89	15	models	model	NNS
cord-322904-9mta0aem	89	16	of	of	IN
cord-322904-9mta0aem	89	17	infection	infection	NN
cord-322904-9mta0aem	90	1	(	(	-LRB-
cord-322904-9mta0aem	90	2	Dubensky	Dubensky	NNP
cord-322904-9mta0aem	90	3	et	et	FW
cord-322904-9mta0aem	90	4	al	al	NNP
cord-322904-9mta0aem	90	5	.	.	NNP
cord-322904-9mta0aem	90	6	,	,	,
cord-322904-9mta0aem	90	7	1991	1991	CD
cord-322904-9mta0aem	90	8	;	;	:
cord-322904-9mta0aem	90	9	Freund	Freund	NNP
cord-322904-9mta0aem	90	10	et	et	NNP
cord-322904-9mta0aem	90	11	al	al	NNP
cord-322904-9mta0aem	90	12	.	.	NNP
cord-322904-9mta0aem	90	13	,	,	,
cord-322904-9mta0aem	90	14	1991a	1991a	CD
cord-322904-9mta0aem	90	15	)	)	-RRB-
cord-322904-9mta0aem	90	16	.	.	.
cord-322904-9mta0aem	91	1	The	the	DT
cord-322904-9mta0aem	91	2	large	large	JJ
cord-322904-9mta0aem	91	3	plaque	plaque	NN
cord-322904-9mta0aem	91	4	strain	strain	NN
cord-322904-9mta0aem	91	5	spread	spread	VBD
cord-322904-9mta0aem	91	6	more	more	RBR
cord-322904-9mta0aem	91	7	efficiently	efficiently	RB
cord-322904-9mta0aem	91	8	in	in	IN
cord-322904-9mta0aem	91	9	mice	mouse	NNS
cord-322904-9mta0aem	91	10	and	and	CC
cord-322904-9mta0aem	91	11	induced	induce	VBN
cord-322904-9mta0aem	91	12	a	a	DT
cord-322904-9mta0aem	91	13	higher	high	JJR
cord-322904-9mta0aem	91	14	frequency	frequency	NN
cord-322904-9mta0aem	91	15	of	of	IN
cord-322904-9mta0aem	91	16	tumors	tumor	NNS
cord-322904-9mta0aem	91	17	and	and	CC
cord-322904-9mta0aem	91	18	the	the	DT
cord-322904-9mta0aem	91	19	tumors	tumor	NNS
cord-322904-9mta0aem	91	20	were	be	VBD
cord-322904-9mta0aem	91	21	more	more	RBR
cord-322904-9mta0aem	91	22	widespread	widespread	JJ
cord-322904-9mta0aem	91	23	than	than	IN
cord-322904-9mta0aem	91	24	those	those	DT
cord-322904-9mta0aem	91	25	caused	cause	VBN
cord-322904-9mta0aem	91	26	by	by	IN
cord-322904-9mta0aem	91	27	the	the	DT
cord-322904-9mta0aem	91	28	small	small	JJ
cord-322904-9mta0aem	91	29	plaque	plaque	NN
cord-322904-9mta0aem	91	30	strains	strain	NNS
cord-322904-9mta0aem	91	31	.	.	.
cord-322904-9mta0aem	92	1	This	this	DT
cord-322904-9mta0aem	92	2	led	lead	VBD
cord-322904-9mta0aem	92	3	to	to	IN
cord-322904-9mta0aem	92	4	the	the	DT
cord-322904-9mta0aem	92	5	hypothesis	hypothesis	NN
cord-322904-9mta0aem	92	6	that	that	IN
cord-322904-9mta0aem	92	7	the	the	DT
cord-322904-9mta0aem	92	8	branched	branched	JJ
cord-322904-9mta0aem	92	9	structures	structure	NNS
cord-322904-9mta0aem	92	10	act	act	VBP
cord-322904-9mta0aem	92	11	as	as	IN
cord-322904-9mta0aem	92	12	pseudoreceptors	pseudoreceptor	NNS
cord-322904-9mta0aem	92	13	that	that	WDT
cord-322904-9mta0aem	92	14	are	be	VBP
cord-322904-9mta0aem	92	15	bound	bind	VBN
cord-322904-9mta0aem	92	16	by	by	IN
cord-322904-9mta0aem	92	17	the	the	DT
cord-322904-9mta0aem	92	18	virus	virus	NN
cord-322904-9mta0aem	92	19	,	,	,
cord-322904-9mta0aem	92	20	but	but	CC
cord-322904-9mta0aem	92	21	do	do	VBP
cord-322904-9mta0aem	92	22	not	not	RB
cord-322904-9mta0aem	92	23	result	result	VB
cord-322904-9mta0aem	92	24	in	in	IN
cord-322904-9mta0aem	92	25	productive	productive	JJ
cord-322904-9mta0aem	92	26	infection	infection	NN
cord-322904-9mta0aem	92	27	.	.	.
cord-322904-9mta0aem	93	1	The	the	DT
cord-322904-9mta0aem	93	2	analysis	analysis	NN
cord-322904-9mta0aem	93	3	of	of	IN
cord-322904-9mta0aem	93	4	virushost	virushost	NN
cord-322904-9mta0aem	93	5	cell	cell	NN
cord-322904-9mta0aem	93	6	interactions	interaction	NNS
cord-322904-9mta0aem	93	7	was	be	VBD
cord-322904-9mta0aem	93	8	thus	thus	RB
cord-322904-9mta0aem	93	9	important	important	JJ
cord-322904-9mta0aem	93	10	for	for	IN
cord-322904-9mta0aem	93	11	understanding	understand	VBG
cord-322904-9mta0aem	93	12	spread	spread	NN
cord-322904-9mta0aem	93	13	and	and	CC
cord-322904-9mta0aem	93	14	pathogenicity	pathogenicity	NN
cord-322904-9mta0aem	93	15	of	of	IN
cord-322904-9mta0aem	93	16	this	this	DT
cord-322904-9mta0aem	93	17	group	group	NN
cord-322904-9mta0aem	93	18	of	of	IN
cord-322904-9mta0aem	93	19	viruses	virus	NNS
cord-322904-9mta0aem	93	20	and	and	CC
cord-322904-9mta0aem	93	21	generated	generate	VBN
cord-322904-9mta0aem	93	22	increased	increase	VBN
cord-322904-9mta0aem	93	23	interest	interest	NN
cord-322904-9mta0aem	93	24	in	in	IN
cord-322904-9mta0aem	93	25	identifying	identify	VBG
cord-322904-9mta0aem	93	26	specific	specific	JJ
cord-322904-9mta0aem	93	27	receptors	receptor	NNS
cord-322904-9mta0aem	93	28	.	.	.
cord-322904-9mta0aem	94	1	The	the	DT
cord-322904-9mta0aem	94	2	Benjamin	Benjamin	NNP
cord-322904-9mta0aem	94	3	lab	lab	NN
cord-322904-9mta0aem	94	4	also	also	RB
cord-322904-9mta0aem	94	5	attempted	attempt	VBD
cord-322904-9mta0aem	94	6	to	to	TO
cord-322904-9mta0aem	94	7	isolate	isolate	VB
cord-322904-9mta0aem	94	8	specific	specific	JJ
cord-322904-9mta0aem	94	9	proteinaceous	proteinaceous	JJ
cord-322904-9mta0aem	94	10	receptors	receptor	NNS
cord-322904-9mta0aem	94	11	for	for	IN
cord-322904-9mta0aem	94	12	mPyV	mpyv	NN
cord-322904-9mta0aem	94	13	by	by	IN
cord-322904-9mta0aem	94	14	producing	produce	VBG
cord-322904-9mta0aem	94	15	and	and	CC
cord-322904-9mta0aem	94	16	screening	screen	VBG
cord-322904-9mta0aem	94	17	several	several	JJ
cord-322904-9mta0aem	94	18	thousand	thousand	CD
cord-322904-9mta0aem	94	19	mononclonal	mononclonal	JJ
cord-322904-9mta0aem	94	20	antibodies	antibody	NNS
cord-322904-9mta0aem	94	21	raised	raise	VBD
cord-322904-9mta0aem	94	22	against	against	IN
cord-322904-9mta0aem	94	23	permissive	permissive	JJ
cord-322904-9mta0aem	94	24	mouse	mouse	NN
cord-322904-9mta0aem	94	25	cell	cell	NN
cord-322904-9mta0aem	94	26	surfaces	surface	NNS
cord-322904-9mta0aem	94	27	(	(	-LRB-
cord-322904-9mta0aem	94	28	Bauer	Bauer	NNP
cord-322904-9mta0aem	94	29	et	et	NNP
cord-322904-9mta0aem	94	30	al	al	NNP
cord-322904-9mta0aem	94	31	.	.	NNP
cord-322904-9mta0aem	94	32	,	,	,
cord-322904-9mta0aem	94	33	1999	1999	CD
cord-322904-9mta0aem	94	34	)	)	-RRB-
cord-322904-9mta0aem	94	35	.	.	.
cord-322904-9mta0aem	95	1	None	none	NN
cord-322904-9mta0aem	95	2	of	of	IN
cord-322904-9mta0aem	95	3	the	the	DT
cord-322904-9mta0aem	95	4	antibodies	antibody	NNS
cord-322904-9mta0aem	95	5	were	be	VBD
cord-322904-9mta0aem	95	6	found	find	VBN
cord-322904-9mta0aem	95	7	capable	capable	JJ
cord-322904-9mta0aem	95	8	of	of	IN
cord-322904-9mta0aem	95	9	inhibiting	inhibit	VBG
cord-322904-9mta0aem	95	10	infection	infection	NN
cord-322904-9mta0aem	95	11	leading	lead	VBG
cord-322904-9mta0aem	95	12	them	-PRON-	PRP
cord-322904-9mta0aem	95	13	to	to	TO
cord-322904-9mta0aem	95	14	conclude	conclude	VB
cord-322904-9mta0aem	95	15	that	that	IN
cord-322904-9mta0aem	95	16	no	no	DT
cord-322904-9mta0aem	95	17	single	single	JJ
cord-322904-9mta0aem	95	18	molecule	molecule	NN
cord-322904-9mta0aem	95	19	on	on	IN
cord-322904-9mta0aem	95	20	the	the	DT
cord-322904-9mta0aem	95	21	surface	surface	NN
cord-322904-9mta0aem	95	22	of	of	IN
cord-322904-9mta0aem	95	23	the	the	DT
cord-322904-9mta0aem	95	24	cells	cell	NNS
cord-322904-9mta0aem	95	25	served	serve	VBD
cord-322904-9mta0aem	95	26	as	as	IN
cord-322904-9mta0aem	95	27	a	a	DT
cord-322904-9mta0aem	95	28	specific	specific	JJ
cord-322904-9mta0aem	95	29	receptor	receptor	NN
cord-322904-9mta0aem	95	30	.	.	.
cord-322904-9mta0aem	96	1	The	the	DT
cord-322904-9mta0aem	96	2	first	first	JJ
cord-322904-9mta0aem	96	3	hint	hint	NN
cord-322904-9mta0aem	96	4	of	of	IN
cord-322904-9mta0aem	96	5	a	a	DT
cord-322904-9mta0aem	96	6	proteinaceous	proteinaceous	JJ
cord-322904-9mta0aem	96	7	receptor	receptor	NN
cord-322904-9mta0aem	96	8	for	for	IN
cord-322904-9mta0aem	96	9	mPyV	mPyV	NNP
cord-322904-9mta0aem	96	10	came	come	VBD
cord-322904-9mta0aem	96	11	from	from	IN
cord-322904-9mta0aem	96	12	studies	study	NNS
cord-322904-9mta0aem	96	13	in	in	IN
cord-322904-9mta0aem	96	14	the	the	DT
cord-322904-9mta0aem	96	15	Amati	Amati	NNP
cord-322904-9mta0aem	96	16	lab	lab	NN
cord-322904-9mta0aem	96	17	where	where	WRB
cord-322904-9mta0aem	96	18	antibodies	antibody	NNS
cord-322904-9mta0aem	96	19	directed	direct	VBN
cord-322904-9mta0aem	96	20	against	against	IN
cord-322904-9mta0aem	96	21	natural	natural	JJ
cord-322904-9mta0aem	96	22	integrin	integrin	NN
cord-322904-9mta0aem	96	23	ligands	ligand	NNS
cord-322904-9mta0aem	96	24	as	as	RB
cord-322904-9mta0aem	96	25	well	well	RB
cord-322904-9mta0aem	96	26	as	as	IN
cord-322904-9mta0aem	96	27	antibodies	antibody	NNS
cord-322904-9mta0aem	96	28	directed	direct	VBN
cord-322904-9mta0aem	96	29	at	at	IN
cord-322904-9mta0aem	96	30	α4β1	α4β1	NNP
cord-322904-9mta0aem	96	31	integrin	integrin	NNP
cord-322904-9mta0aem	96	32	inhibited	inhibit	VBD
cord-322904-9mta0aem	96	33	a	a	DT
cord-322904-9mta0aem	96	34	post	post	JJ
cord-322904-9mta0aem	96	35	-	-	JJ
cord-322904-9mta0aem	96	36	attachment	attachment	JJ
cord-322904-9mta0aem	96	37	step	step	NN
cord-322904-9mta0aem	96	38	in	in	IN
cord-322904-9mta0aem	96	39	infection	infection	NN
cord-322904-9mta0aem	96	40	(	(	-LRB-
cord-322904-9mta0aem	96	41	Caruso	Caruso	NNP
cord-322904-9mta0aem	96	42	et	et	NNP
cord-322904-9mta0aem	96	43	al	al	NNP
cord-322904-9mta0aem	96	44	.	.	.
cord-322904-9mta0aem	97	1	,	,	,
cord-322904-9mta0aem	97	2	2003	2003	CD
cord-322904-9mta0aem	97	3	)	)	-RRB-
cord-322904-9mta0aem	97	4	(	(	-LRB-
cord-322904-9mta0aem	97	5	Table	table	NN
cord-322904-9mta0aem	97	6	1	1	CD
cord-322904-9mta0aem	97	7	)	)	-RRB-
cord-322904-9mta0aem	97	8	.	.	.
cord-322904-9mta0aem	98	1	This	this	DT
cord-322904-9mta0aem	98	2	was	be	VBD
cord-322904-9mta0aem	98	3	found	find	VBN
cord-322904-9mta0aem	98	4	to	to	TO
cord-322904-9mta0aem	98	5	be	be	VB
cord-322904-9mta0aem	98	6	mediated	mediate	VBN
cord-322904-9mta0aem	98	7	by	by	IN
cord-322904-9mta0aem	98	8	an	an	DT
cord-322904-9mta0aem	98	9	LDV	LDV	NNP
cord-322904-9mta0aem	98	10	integrin	integrin	NN
cord-322904-9mta0aem	98	11	binding	bind	VBG
cord-322904-9mta0aem	98	12	motif	motif	NN
cord-322904-9mta0aem	98	13	present	present	JJ
cord-322904-9mta0aem	98	14	in	in	IN
cord-322904-9mta0aem	98	15	mPyV	mpyv	JJ
cord-322904-9mta0aem	98	16	VP1	vp1	NN
cord-322904-9mta0aem	98	17	as	as	IN
cord-322904-9mta0aem	98	18	a	a	DT
cord-322904-9mta0aem	98	19	specific	specific	JJ
cord-322904-9mta0aem	98	20	mutation	mutation	NN
cord-322904-9mta0aem	98	21	in	in	IN
cord-322904-9mta0aem	98	22	this	this	DT
cord-322904-9mta0aem	98	23	motif	motif	NN
cord-322904-9mta0aem	98	24	reduces	reduce	VBZ
cord-322904-9mta0aem	98	25	JCV	JCV	NNP
cord-322904-9mta0aem	98	26	is	be	VBZ
cord-322904-9mta0aem	98	27	unique	unique	JJ
cord-322904-9mta0aem	98	28	in	in	IN
cord-322904-9mta0aem	98	29	that	that	IN
cord-322904-9mta0aem	98	30	it	-PRON-	PRP
cord-322904-9mta0aem	98	31	initially	initially	RB
cord-322904-9mta0aem	98	32	enters	enter	VBZ
cord-322904-9mta0aem	98	33	cells	cell	NNS
cord-322904-9mta0aem	98	34	by	by	IN
cord-322904-9mta0aem	98	35	clathrin	clathrin	NN
cord-322904-9mta0aem	98	36	dependent	dependent	JJ
cord-322904-9mta0aem	98	37	endocytosis	endocytosis	NN
cord-322904-9mta0aem	98	38	.	.	.
cord-322904-9mta0aem	99	1	The	the	DT
cord-322904-9mta0aem	99	2	virus	virus	NN
cord-322904-9mta0aem	99	3	then	then	RB
cord-322904-9mta0aem	99	4	traffics	traffic	VBZ
cord-322904-9mta0aem	99	5	to	to	IN
cord-322904-9mta0aem	99	6	early	early	JJ
cord-322904-9mta0aem	99	7	endosomes	endosome	NNS
cord-322904-9mta0aem	99	8	and	and	CC
cord-322904-9mta0aem	99	9	then	then	RB
cord-322904-9mta0aem	99	10	to	to	IN
cord-322904-9mta0aem	99	11	caveosomes	caveosome	NNS
cord-322904-9mta0aem	99	12	.	.	.
cord-322904-9mta0aem	100	1	BKV	BKV	NNP
cord-322904-9mta0aem	100	2	,	,	,
cord-322904-9mta0aem	100	3	SV40	SV40	NNP
cord-322904-9mta0aem	100	4	,	,	,
cord-322904-9mta0aem	100	5	and	and	CC
cord-322904-9mta0aem	100	6	mPyV	mpyv	NN
cord-322904-9mta0aem	100	7	are	be	VBP
cord-322904-9mta0aem	100	8	reported	report	VBN
cord-322904-9mta0aem	100	9	to	to	TO
cord-322904-9mta0aem	100	10	use	use	VB
cord-322904-9mta0aem	100	11	caveolae	caveolae	NNP
cord-322904-9mta0aem	100	12	dependent	dependent	JJ
cord-322904-9mta0aem	100	13	mechanisms	mechanism	NNS
cord-322904-9mta0aem	100	14	of	of	IN
cord-322904-9mta0aem	100	15	entry	entry	NN
cord-322904-9mta0aem	100	16	that	that	DT
cord-322904-9mta0aem	100	17	traffic	traffic	NN
cord-322904-9mta0aem	100	18	these	these	DT
cord-322904-9mta0aem	100	19	viruses	virus	NNS
cord-322904-9mta0aem	100	20	to	to	IN
cord-322904-9mta0aem	100	21	caveosomes	caveosome	NNS
cord-322904-9mta0aem	100	22	.	.	.
cord-322904-9mta0aem	101	1	SV40	SV40	NNP
cord-322904-9mta0aem	101	2	and	and	CC
cord-322904-9mta0aem	101	3	mPyV	mPyV	NNP
cord-322904-9mta0aem	101	4	can	can	MD
cord-322904-9mta0aem	101	5	also	also	RB
cord-322904-9mta0aem	101	6	use	use	VB
cord-322904-9mta0aem	101	7	non	non	JJ
cord-322904-9mta0aem	101	8	-	-	JJ
cord-322904-9mta0aem	101	9	caveolar	caveolar	JJ
cord-322904-9mta0aem	101	10	but	but	CC
cord-322904-9mta0aem	101	11	cholesterol	cholesterol	NN
cord-322904-9mta0aem	101	12	dependent	dependent	JJ
cord-322904-9mta0aem	101	13	mechanisms	mechanism	NNS
cord-322904-9mta0aem	101	14	of	of	IN
cord-322904-9mta0aem	101	15	entry	entry	NN
cord-322904-9mta0aem	101	16	to	to	TO
cord-322904-9mta0aem	101	17	access	access	VB
cord-322904-9mta0aem	101	18	the	the	DT
cord-322904-9mta0aem	101	19	caveosome	caveosome	NN
cord-322904-9mta0aem	101	20	and	and	CC
cord-322904-9mta0aem	101	21	the	the	DT
cord-322904-9mta0aem	101	22	mechanism	mechanism	NN
cord-322904-9mta0aem	101	23	used	use	VBN
cord-322904-9mta0aem	101	24	depends	depend	VBZ
cord-322904-9mta0aem	101	25	on	on	IN
cord-322904-9mta0aem	101	26	cell	cell	NN
cord-322904-9mta0aem	101	27	type	type	NN
cord-322904-9mta0aem	101	28	.	.	.
cord-322904-9mta0aem	102	1	Once	once	RB
cord-322904-9mta0aem	102	2	in	in	IN
cord-322904-9mta0aem	102	3	the	the	DT
cord-322904-9mta0aem	102	4	caveosome	caveosome	VBN
cord-322904-9mta0aem	102	5	SV40	SV40	NNP
cord-322904-9mta0aem	102	6	and	and	CC
cord-322904-9mta0aem	102	7	mPyV	mpyv	JJ
cord-322904-9mta0aem	102	8	traffic	traffic	NN
cord-322904-9mta0aem	102	9	to	to	IN
cord-322904-9mta0aem	102	10	the	the	DT
cord-322904-9mta0aem	102	11	endoplasmic	endoplasmic	NN
cord-322904-9mta0aem	102	12	reticulum	reticulum	NN
cord-322904-9mta0aem	102	13	in	in	IN
cord-322904-9mta0aem	102	14	tubular	tubular	JJ
cord-322904-9mta0aem	102	15	structures	structure	NNS
cord-322904-9mta0aem	102	16	that	that	WDT
cord-322904-9mta0aem	102	17	bud	bud	VBP
cord-322904-9mta0aem	102	18	off	off	RP
cord-322904-9mta0aem	102	19	the	the	DT
cord-322904-9mta0aem	102	20	ER	ER	NNP
cord-322904-9mta0aem	102	21	membrane	membrane	NN
cord-322904-9mta0aem	102	22	.	.	.
cord-322904-9mta0aem	103	1	It	-PRON-	PRP
cord-322904-9mta0aem	103	2	is	be	VBZ
cord-322904-9mta0aem	103	3	presumed	presume	VBN
cord-322904-9mta0aem	103	4	that	that	IN
cord-322904-9mta0aem	103	5	JCV	JCV	NNP
cord-322904-9mta0aem	103	6	and	and	CC
cord-322904-9mta0aem	103	7	BKV	BKV	NNP
cord-322904-9mta0aem	103	8	use	use	VBP
cord-322904-9mta0aem	103	9	the	the	DT
cord-322904-9mta0aem	103	10	same	same	JJ
cord-322904-9mta0aem	103	11	pathway	pathway	NN
cord-322904-9mta0aem	103	12	but	but	CC
cord-322904-9mta0aem	103	13	data	datum	NNS
cord-322904-9mta0aem	103	14	on	on	IN
cord-322904-9mta0aem	103	15	this	this	DT
cord-322904-9mta0aem	103	16	is	be	VBZ
cord-322904-9mta0aem	103	17	lacking	lack	VBG
cord-322904-9mta0aem	103	18	.	.	.
cord-322904-9mta0aem	104	1	Adapted	adapt	VBN
cord-322904-9mta0aem	104	2	from	from	IN
cord-322904-9mta0aem	104	3	Marsh	Marsh	NNP
cord-322904-9mta0aem	104	4	and	and	CC
cord-322904-9mta0aem	104	5	Helenius	Helenius	NNP
cord-322904-9mta0aem	104	6	,	,	,
cord-322904-9mta0aem	104	7	1989	1989	CD
cord-322904-9mta0aem	104	8	.	.	.
cord-322904-9mta0aem	105	1	infectivity	infectivity	NN
cord-322904-9mta0aem	105	2	(	(	-LRB-
cord-322904-9mta0aem	105	3	Caruso	Caruso	NNP
cord-322904-9mta0aem	105	4	et	et	NNP
cord-322904-9mta0aem	105	5	al	al	NNP
cord-322904-9mta0aem	105	6	.	.	NNP
cord-322904-9mta0aem	105	7	,	,	,
cord-322904-9mta0aem	105	8	2007	2007	CD
cord-322904-9mta0aem	105	9	)	)	-RRB-
cord-322904-9mta0aem	105	10	.	.	.
cord-322904-9mta0aem	106	1	Interestingly	interestingly	RB
cord-322904-9mta0aem	106	2	,	,	,
cord-322904-9mta0aem	106	3	when	when	WRB
cord-322904-9mta0aem	106	4	inoculated	inoculate	VBN
cord-322904-9mta0aem	106	5	into	into	IN
cord-322904-9mta0aem	106	6	newborn	newborn	JJ
cord-322904-9mta0aem	106	7	mice	mouse	NNS
cord-322904-9mta0aem	106	8	,	,	,
cord-322904-9mta0aem	106	9	the	the	DT
cord-322904-9mta0aem	106	10	mPyV	mpyv	NN
cord-322904-9mta0aem	106	11	displays	display	VBZ
cord-322904-9mta0aem	106	12	an	an	DT
cord-322904-9mta0aem	106	13	altered	altered	JJ
cord-322904-9mta0aem	106	14	pattern	pattern	NN
cord-322904-9mta0aem	106	15	of	of	IN
cord-322904-9mta0aem	106	16	infection	infection	NN
cord-322904-9mta0aem	106	17	when	when	WRB
cord-322904-9mta0aem	106	18	compared	compare	VBN
cord-322904-9mta0aem	106	19	to	to	IN
cord-322904-9mta0aem	106	20	wild	wild	JJ
cord-322904-9mta0aem	106	21	type	type	NN
cord-322904-9mta0aem	106	22	(	(	-LRB-
cord-322904-9mta0aem	106	23	Caruso	Caruso	NNP
cord-322904-9mta0aem	106	24	et	et	NNP
cord-322904-9mta0aem	106	25	al	al	NNP
cord-322904-9mta0aem	106	26	.	.	NNP
cord-322904-9mta0aem	106	27	,	,	,
cord-322904-9mta0aem	106	28	2007	2007	CD
cord-322904-9mta0aem	106	29	)	)	-RRB-
cord-322904-9mta0aem	106	30	.	.	.
cord-322904-9mta0aem	107	1	Previous	previous	JJ
cord-322904-9mta0aem	107	2	receptor	receptor	NN
cord-322904-9mta0aem	107	3	hunting	hunting	NN
cord-322904-9mta0aem	107	4	experiments	experiment	NNS
cord-322904-9mta0aem	107	5	described	describe	VBN
cord-322904-9mta0aem	107	6	above	above	RB
cord-322904-9mta0aem	107	7	would	would	MD
cord-322904-9mta0aem	107	8	have	have	VB
cord-322904-9mta0aem	107	9	missed	miss	VBN
cord-322904-9mta0aem	107	10	this	this	DT
cord-322904-9mta0aem	107	11	ligand	ligand	NN
cord-322904-9mta0aem	107	12	as	as	IN
cord-322904-9mta0aem	107	13	the	the	DT
cord-322904-9mta0aem	107	14	virus	virus	NN
cord-322904-9mta0aem	107	15	apparently	apparently	RB
cord-322904-9mta0aem	107	16	needs	need	VBZ
cord-322904-9mta0aem	107	17	to	to	TO
cord-322904-9mta0aem	107	18	undergo	undergo	VB
cord-322904-9mta0aem	107	19	a	a	DT
cord-322904-9mta0aem	107	20	conformational	conformational	JJ
cord-322904-9mta0aem	107	21	change	change	NN
cord-322904-9mta0aem	107	22	after	after	IN
cord-322904-9mta0aem	107	23	binding	bind	VBG
cord-322904-9mta0aem	107	24	to	to	IN
cord-322904-9mta0aem	107	25	sialic	sialic	JJ
cord-322904-9mta0aem	107	26	acid	acid	NN
cord-322904-9mta0aem	107	27	that	that	WDT
cord-322904-9mta0aem	107	28	then	then	RB
cord-322904-9mta0aem	107	29	allows	allow	VBZ
cord-322904-9mta0aem	107	30	it	-PRON-	PRP
cord-322904-9mta0aem	107	31	to	to	TO
cord-322904-9mta0aem	107	32	bind	bind	VB
cord-322904-9mta0aem	107	33	to	to	IN
cord-322904-9mta0aem	107	34	the	the	DT
cord-322904-9mta0aem	107	35	integrin	integrin	NN
cord-322904-9mta0aem	107	36	receptors	receptor	NNS
cord-322904-9mta0aem	107	37	as	as	IN
cord-322904-9mta0aem	107	38	a	a	DT
cord-322904-9mta0aem	107	39	second	second	JJ
cord-322904-9mta0aem	107	40	step	step	NN
cord-322904-9mta0aem	107	41	in	in	IN
cord-322904-9mta0aem	107	42	the	the	DT
cord-322904-9mta0aem	107	43	entry	entry	NN
cord-322904-9mta0aem	107	44	process	process	NN
cord-322904-9mta0aem	107	45	.	.	.
cord-322904-9mta0aem	108	1	It	-PRON-	PRP
cord-322904-9mta0aem	108	2	is	be	VBZ
cord-322904-9mta0aem	108	3	not	not	RB
cord-322904-9mta0aem	108	4	certain	certain	JJ
cord-322904-9mta0aem	108	5	whether	whether	IN
cord-322904-9mta0aem	108	6	infection	infection	NN
cord-322904-9mta0aem	108	7	of	of	IN
cord-322904-9mta0aem	108	8	all	all	DT
cord-322904-9mta0aem	108	9	cells	cell	NNS
cord-322904-9mta0aem	108	10	requires	require	VBZ
cord-322904-9mta0aem	108	11	this	this	DT
cord-322904-9mta0aem	108	12	second	second	JJ
cord-322904-9mta0aem	108	13	step	step	NN
cord-322904-9mta0aem	108	14	but	but	CC
cord-322904-9mta0aem	108	15	it	-PRON-	PRP
cord-322904-9mta0aem	108	16	is	be	VBZ
cord-322904-9mta0aem	108	17	clear	clear	JJ
cord-322904-9mta0aem	108	18	that	that	IN
cord-322904-9mta0aem	108	19	in	in	IN
cord-322904-9mta0aem	108	20	some	some	DT
cord-322904-9mta0aem	108	21	cases	case	NNS
cord-322904-9mta0aem	108	22	it	-PRON-	PRP
cord-322904-9mta0aem	108	23	is	be	VBZ
cord-322904-9mta0aem	108	24	utilized	utilize	VBN
cord-322904-9mta0aem	108	25	.	.	.
cord-322904-9mta0aem	109	1	However	however	RB
cord-322904-9mta0aem	109	2	,	,	,
cord-322904-9mta0aem	109	3	the	the	DT
cord-322904-9mta0aem	109	4	LDV	LDV	NNP
cord-322904-9mta0aem	109	5	motif	motif	NN
cord-322904-9mta0aem	109	6	is	be	VBZ
cord-322904-9mta0aem	109	7	buried	bury	VBN
cord-322904-9mta0aem	109	8	under	under	IN
cord-322904-9mta0aem	109	9	the	the	DT
cord-322904-9mta0aem	109	10	receptor	receptor	NN
cord-322904-9mta0aem	109	11	binding	bind	VBG
cord-322904-9mta0aem	109	12	loops	loop	NNS
cord-322904-9mta0aem	109	13	deep	deep	RB
cord-322904-9mta0aem	109	14	within	within	IN
cord-322904-9mta0aem	109	15	VP1	VP1	NNP
cord-322904-9mta0aem	109	16	,	,	,
cord-322904-9mta0aem	109	17	and	and	CC
cord-322904-9mta0aem	109	18	the	the	DT
cord-322904-9mta0aem	109	19	mutation	mutation	NN
cord-322904-9mta0aem	109	20	could	could	MD
cord-322904-9mta0aem	109	21	have	have	VB
cord-322904-9mta0aem	109	22	affected	affect	VBN
cord-322904-9mta0aem	109	23	the	the	DT
cord-322904-9mta0aem	109	24	structure	structure	NN
cord-322904-9mta0aem	109	25	of	of	IN
cord-322904-9mta0aem	109	26	the	the	DT
cord-322904-9mta0aem	109	27	binding	binding	NN
cord-322904-9mta0aem	109	28	site	site	NN
cord-322904-9mta0aem	109	29	indirectly	indirectly	RB
cord-322904-9mta0aem	109	30	.	.	.
cord-322904-9mta0aem	110	1	Recent	recent	JJ
cord-322904-9mta0aem	110	2	studies	study	NNS
cord-322904-9mta0aem	110	3	from	from	IN
cord-322904-9mta0aem	110	4	both	both	DT
cord-322904-9mta0aem	110	5	the	the	DT
cord-322904-9mta0aem	110	6	Benjamin	Benjamin	NNP
cord-322904-9mta0aem	110	7	and	and	CC
cord-322904-9mta0aem	110	8	Rapoport	Rapoport	NNP
cord-322904-9mta0aem	110	9	groups	group	NNS
cord-322904-9mta0aem	110	10	clearly	clearly	RB
cord-322904-9mta0aem	110	11	delineated	delineate	VBD
cord-322904-9mta0aem	110	12	a	a	DT
cord-322904-9mta0aem	110	13	role	role	NN
cord-322904-9mta0aem	110	14	for	for	IN
cord-322904-9mta0aem	110	15	the	the	DT
cord-322904-9mta0aem	110	16	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	110	17	GD1a	GD1a	NNP
cord-322904-9mta0aem	110	18	and	and	CC
cord-322904-9mta0aem	110	19	GT1b	GT1b	NNP
cord-322904-9mta0aem	110	20	in	in	IN
cord-322904-9mta0aem	110	21	mPyV	mpyv	JJ
cord-322904-9mta0aem	110	22	infection	infection	NN
cord-322904-9mta0aem	110	23	and	and	CC
cord-322904-9mta0aem	110	24	for	for	IN
cord-322904-9mta0aem	110	25	the	the	DT
cord-322904-9mta0aem	110	26	ganglioside	ganglioside	NN
cord-322904-9mta0aem	110	27	GM1	GM1	NNP
cord-322904-9mta0aem	110	28	in	in	IN
cord-322904-9mta0aem	110	29	SV40	SV40	NNP
cord-322904-9mta0aem	110	30	infection	infection	NN
cord-322904-9mta0aem	111	1	(	(	-LRB-
cord-322904-9mta0aem	111	2	Gilbert	Gilbert	NNP
cord-322904-9mta0aem	111	3	and	and	CC
cord-322904-9mta0aem	111	4	Benjamin	Benjamin	NNP
cord-322904-9mta0aem	111	5	,	,	,
cord-322904-9mta0aem	111	6	2004	2004	CD
cord-322904-9mta0aem	111	7	;	;	:
cord-322904-9mta0aem	111	8	Gilbert	Gilbert	NNP
cord-322904-9mta0aem	111	9	et	et	NNP
cord-322904-9mta0aem	111	10	al	al	NNP
cord-322904-9mta0aem	111	11	.	.	NNP
cord-322904-9mta0aem	111	12	,	,	,
cord-322904-9mta0aem	111	13	2005	2005	CD
cord-322904-9mta0aem	111	14	;	;	:
cord-322904-9mta0aem	112	1	Tsai	Tsai	NNP
cord-322904-9mta0aem	112	2	et	et	NNP
cord-322904-9mta0aem	112	3	al	al	NNP
cord-322904-9mta0aem	112	4	.	.	NNP
cord-322904-9mta0aem	112	5	,	,	,
cord-322904-9mta0aem	112	6	2003	2003	CD
cord-322904-9mta0aem	112	7	)	)	-RRB-
cord-322904-9mta0aem	113	1	(	(	-LRB-
cord-322904-9mta0aem	113	2	Table	table	NN
cord-322904-9mta0aem	113	3	1	1	CD
cord-322904-9mta0aem	113	4	)	)	-RRB-
cord-322904-9mta0aem	113	5	.	.	.
cord-322904-9mta0aem	114	1	The	the	DT
cord-322904-9mta0aem	114	2	Rapoport	Rapoport	NNP
cord-322904-9mta0aem	114	3	group	group	NN
cord-322904-9mta0aem	114	4	used	use	VBD
cord-322904-9mta0aem	114	5	sucrose	sucrose	NN
cord-322904-9mta0aem	114	6	flotation	flotation	NN
cord-322904-9mta0aem	114	7	assays	assay	NNS
cord-322904-9mta0aem	114	8	to	to	TO
cord-322904-9mta0aem	114	9	initially	initially	RB
cord-322904-9mta0aem	114	10	ask	ask	VB
cord-322904-9mta0aem	114	11	whether	whether	IN
cord-322904-9mta0aem	114	12	mPyV	mpyv	NN
cord-322904-9mta0aem	114	13	would	would	MD
cord-322904-9mta0aem	114	14	float	float	VB
cord-322904-9mta0aem	114	15	when	when	WRB
cord-322904-9mta0aem	114	16	mixed	mix	VBN
cord-322904-9mta0aem	114	17	with	with	IN
cord-322904-9mta0aem	114	18	plasma	plasma	NN
cord-322904-9mta0aem	114	19	membrane	membrane	NN
cord-322904-9mta0aem	114	20	preparations	preparation	NNS
cord-322904-9mta0aem	114	21	from	from	IN
cord-322904-9mta0aem	114	22	human	human	JJ
cord-322904-9mta0aem	114	23	erythrocytes	erythrocyte	NNS
cord-322904-9mta0aem	114	24	,	,	,
cord-322904-9mta0aem	114	25	from	from	IN
cord-322904-9mta0aem	114	26	bacterial	bacterial	JJ
cord-322904-9mta0aem	114	27	membranes	membrane	NNS
cord-322904-9mta0aem	114	28	or	or	CC
cord-322904-9mta0aem	114	29	from	from	IN
cord-322904-9mta0aem	114	30	yeast	yeast	NN
cord-322904-9mta0aem	114	31	membranes	membrane	NNS
cord-322904-9mta0aem	114	32	.	.	.
cord-322904-9mta0aem	115	1	They	-PRON-	PRP
cord-322904-9mta0aem	115	2	found	find	VBD
cord-322904-9mta0aem	115	3	that	that	IN
cord-322904-9mta0aem	115	4	when	when	WRB
cord-322904-9mta0aem	115	5	mPyV	mPyV	NNP
cord-322904-9mta0aem	115	6	was	be	VBD
cord-322904-9mta0aem	115	7	incubated	incubate	VBN
cord-322904-9mta0aem	115	8	with	with	IN
cord-322904-9mta0aem	115	9	buffer	buffer	NN
cord-322904-9mta0aem	115	10	or	or	CC
cord-322904-9mta0aem	115	11	with	with	IN
cord-322904-9mta0aem	115	12	either	either	CC
cord-322904-9mta0aem	115	13	bacterial	bacterial	JJ
cord-322904-9mta0aem	115	14	or	or	CC
cord-322904-9mta0aem	115	15	yeast	yeast	NN
cord-322904-9mta0aem	115	16	membranes	membrane	NNS
cord-322904-9mta0aem	115	17	the	the	DT
cord-322904-9mta0aem	115	18	virus	virus	NN
cord-322904-9mta0aem	115	19	fractionated	fractionate	VBN
cord-322904-9mta0aem	115	20	in	in	IN
cord-322904-9mta0aem	115	21	the	the	DT
cord-322904-9mta0aem	115	22	bottom	bottom	NN
cord-322904-9mta0aem	115	23	third	third	JJ
cord-322904-9mta0aem	115	24	of	of	IN
cord-322904-9mta0aem	115	25	the	the	DT
cord-322904-9mta0aem	115	26	gradient	gradient	NN
cord-322904-9mta0aem	115	27	.	.	.
cord-322904-9mta0aem	116	1	When	when	WRB
cord-322904-9mta0aem	116	2	mPyV	mPyV	NNP
cord-322904-9mta0aem	116	3	was	be	VBD
cord-322904-9mta0aem	116	4	incubated	incubate	VBN
cord-322904-9mta0aem	116	5	with	with	IN
cord-322904-9mta0aem	116	6	plasma	plasma	NN
cord-322904-9mta0aem	116	7	membrane	membrane	NN
cord-322904-9mta0aem	116	8	from	from	IN
cord-322904-9mta0aem	116	9	human	human	JJ
cord-322904-9mta0aem	116	10	erythrocytes	erythrocyte	NNS
cord-322904-9mta0aem	116	11	the	the	DT
cord-322904-9mta0aem	116	12	virus	virus	NN
cord-322904-9mta0aem	116	13	floated	float	VBD
cord-322904-9mta0aem	116	14	to	to	IN
cord-322904-9mta0aem	116	15	the	the	DT
cord-322904-9mta0aem	116	16	top	top	NN
cord-322904-9mta0aem	116	17	of	of	IN
cord-322904-9mta0aem	116	18	the	the	DT
cord-322904-9mta0aem	116	19	gradient	gradient	NN
cord-322904-9mta0aem	116	20	indicating	indicate	VBG
cord-322904-9mta0aem	116	21	an	an	DT
cord-322904-9mta0aem	116	22	association	association	NN
cord-322904-9mta0aem	116	23	with	with	IN
cord-322904-9mta0aem	116	24	plasma	plasma	NN
cord-322904-9mta0aem	116	25	membrane	membrane	NN
cord-322904-9mta0aem	116	26	lipids	lipid	NNS
cord-322904-9mta0aem	116	27	.	.	.
cord-322904-9mta0aem	117	1	Upon	upon	IN
cord-322904-9mta0aem	117	2	treatment	treatment	NN
cord-322904-9mta0aem	117	3	of	of	IN
cord-322904-9mta0aem	117	4	the	the	DT
cord-322904-9mta0aem	117	5	plasma	plasma	NN
cord-322904-9mta0aem	117	6	membranes	membrane	NNS
cord-322904-9mta0aem	117	7	with	with	IN
cord-322904-9mta0aem	117	8	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	117	9	the	the	DT
cord-322904-9mta0aem	117	10	virus	virus	NN
cord-322904-9mta0aem	117	11	failed	fail	VBD
cord-322904-9mta0aem	117	12	to	to	TO
cord-322904-9mta0aem	117	13	float	float	VB
cord-322904-9mta0aem	117	14	and	and	CC
cord-322904-9mta0aem	117	15	fractionated	fractionate	VBN
cord-322904-9mta0aem	117	16	at	at	IN
cord-322904-9mta0aem	117	17	the	the	DT
cord-322904-9mta0aem	117	18	bottom	bottom	NN
cord-322904-9mta0aem	117	19	of	of	IN
cord-322904-9mta0aem	117	20	the	the	DT
cord-322904-9mta0aem	117	21	gradient	gradient	NN
cord-322904-9mta0aem	117	22	.	.	.
cord-322904-9mta0aem	118	1	Specific	specific	JJ
cord-322904-9mta0aem	118	2	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	118	3	were	be	VBD
cord-322904-9mta0aem	118	4	then	then	RB
cord-322904-9mta0aem	118	5	tested	test	VBN
cord-322904-9mta0aem	118	6	for	for	IN
cord-322904-9mta0aem	118	7	their	-PRON-	PRP$
cord-322904-9mta0aem	118	8	ability	ability	NN
cord-322904-9mta0aem	118	9	to	to	TO
cord-322904-9mta0aem	118	10	interact	interact	VB
cord-322904-9mta0aem	118	11	with	with	IN
cord-322904-9mta0aem	118	12	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	118	13	.	.	.
cord-322904-9mta0aem	119	1	mPyV	mPyV	NNP
cord-322904-9mta0aem	119	2	only	only	RB
cord-322904-9mta0aem	119	3	floated	float	VBD
cord-322904-9mta0aem	119	4	to	to	IN
cord-322904-9mta0aem	119	5	the	the	DT
cord-322904-9mta0aem	119	6	top	top	NN
cord-322904-9mta0aem	119	7	of	of	IN
cord-322904-9mta0aem	119	8	the	the	DT
cord-322904-9mta0aem	119	9	gradient	gradient	NN
cord-322904-9mta0aem	119	10	in	in	IN
cord-322904-9mta0aem	119	11	the	the	DT
cord-322904-9mta0aem	119	12	presence	presence	NN
cord-322904-9mta0aem	119	13	of	of	IN
cord-322904-9mta0aem	119	14	GD1	GD1	NNP
cord-322904-9mta0aem	119	15	and	and	CC
cord-322904-9mta0aem	119	16	GT1b	GT1b	NNP
cord-322904-9mta0aem	119	17	,	,	,
cord-322904-9mta0aem	119	18	and	and	CC
cord-322904-9mta0aem	119	19	SV40	SV40	NNP
cord-322904-9mta0aem	119	20	only	only	RB
cord-322904-9mta0aem	119	21	floated	float	VBD
cord-322904-9mta0aem	119	22	to	to	IN
cord-322904-9mta0aem	119	23	the	the	DT
cord-322904-9mta0aem	119	24	top	top	NN
cord-322904-9mta0aem	119	25	of	of	IN
cord-322904-9mta0aem	119	26	the	the	DT
cord-322904-9mta0aem	119	27	gradient	gradient	NN
cord-322904-9mta0aem	119	28	in	in	IN
cord-322904-9mta0aem	119	29	presence	presence	NN
cord-322904-9mta0aem	119	30	of	of	IN
cord-322904-9mta0aem	119	31	GM1	GM1	NNP
cord-322904-9mta0aem	119	32	.	.	.
cord-322904-9mta0aem	120	1	The	the	DT
cord-322904-9mta0aem	120	2	group	group	NN
cord-322904-9mta0aem	120	3	then	then	RB
cord-322904-9mta0aem	120	4	showed	show	VBD
cord-322904-9mta0aem	120	5	that	that	IN
cord-322904-9mta0aem	120	6	rat	rat	NN
cord-322904-9mta0aem	120	7	cells	cell	NNS
cord-322904-9mta0aem	120	8	cell	cell	NN
cord-322904-9mta0aem	120	9	deficient	deficient	JJ
cord-322904-9mta0aem	120	10	in	in	IN
cord-322904-9mta0aem	120	11	complex	complex	JJ
cord-322904-9mta0aem	120	12	ganglioside	ganglioside	NN
cord-322904-9mta0aem	120	13	biosynthesis	biosynthesis	NN
cord-322904-9mta0aem	120	14	are	be	VBP
cord-322904-9mta0aem	120	15	poorly	poorly	RB
cord-322904-9mta0aem	120	16	susceptible	susceptible	JJ
cord-322904-9mta0aem	120	17	to	to	IN
cord-322904-9mta0aem	120	18	mPyV	mpyv	JJ
cord-322904-9mta0aem	120	19	and	and	CC
cord-322904-9mta0aem	120	20	SV40	SV40	NNP
cord-322904-9mta0aem	120	21	infection	infection	NN
cord-322904-9mta0aem	120	22	.	.	.
cord-322904-9mta0aem	121	1	However	however	RB
cord-322904-9mta0aem	121	2	,	,	,
cord-322904-9mta0aem	121	3	when	when	WRB
cord-322904-9mta0aem	121	4	preincubated	preincubate	VBN
cord-322904-9mta0aem	121	5	with	with	IN
cord-322904-9mta0aem	121	6	GD1a	GD1a	NNP
cord-322904-9mta0aem	121	7	or	or	CC
cord-322904-9mta0aem	121	8	GT1b	GT1b	NNP
cord-322904-9mta0aem	121	9	they	-PRON-	PRP
cord-322904-9mta0aem	121	10	become	become	VBP
cord-322904-9mta0aem	121	11	highly	highly	RB
cord-322904-9mta0aem	121	12	susceptible	susceptible	JJ
cord-322904-9mta0aem	121	13	to	to	IN
cord-322904-9mta0aem	121	14	mPyV	mPyV	NNP
cord-322904-9mta0aem	121	15	and	and	CC
cord-322904-9mta0aem	121	16	GM1	GM1	NNP
cord-322904-9mta0aem	121	17	restores	restore	VBZ
cord-322904-9mta0aem	121	18	susceptibility	susceptibility	NN
cord-322904-9mta0aem	121	19	to	to	IN
cord-322904-9mta0aem	121	20	SV40	SV40	NNP
cord-322904-9mta0aem	121	21	.	.	.
cord-322904-9mta0aem	122	1	Fluorescent	fluorescent	NN
cord-322904-9mta0aem	122	2	co	co	NN
cord-322904-9mta0aem	122	3	-	-	NN
cord-322904-9mta0aem	122	4	localization	localization	JJ
cord-322904-9mta0aem	122	5	studies	study	NNS
cord-322904-9mta0aem	122	6	indicated	indicate	VBD
cord-322904-9mta0aem	122	7	that	that	IN
cord-322904-9mta0aem	122	8	the	the	DT
cord-322904-9mta0aem	122	9	virus	virus	NN
cord-322904-9mta0aem	122	10	traffics	traffic	VBZ
cord-322904-9mta0aem	122	11	directly	directly	RB
cord-322904-9mta0aem	122	12	to	to	IN
cord-322904-9mta0aem	122	13	the	the	DT
cord-322904-9mta0aem	122	14	ER	ER	NNP
cord-322904-9mta0aem	122	15	with	with	IN
cord-322904-9mta0aem	122	16	the	the	DT
cord-322904-9mta0aem	122	17	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	123	1	(	(	-LRB-
cord-322904-9mta0aem	123	2	Fig	Fig	NNP
cord-322904-9mta0aem	123	3	.	.	NNP
cord-322904-9mta0aem	123	4	2	2	CD
cord-322904-9mta0aem	123	5	)	)	-RRB-
cord-322904-9mta0aem	123	6	.	.	.
cord-322904-9mta0aem	124	1	This	this	DT
cord-322904-9mta0aem	124	2	mode	mode	NN
cord-322904-9mta0aem	124	3	of	of	IN
cord-322904-9mta0aem	124	4	internalization	internalization	NN
cord-322904-9mta0aem	124	5	is	be	VBZ
cord-322904-9mta0aem	124	6	strikingly	strikingly	RB
cord-322904-9mta0aem	124	7	similar	similar	JJ
cord-322904-9mta0aem	124	8	to	to	IN
cord-322904-9mta0aem	124	9	the	the	DT
cord-322904-9mta0aem	124	10	one	one	NN
cord-322904-9mta0aem	124	11	used	use	VBN
cord-322904-9mta0aem	124	12	by	by	IN
cord-322904-9mta0aem	124	13	ER	ER	NNP
cord-322904-9mta0aem	124	14	directed	direct	VBD
cord-322904-9mta0aem	124	15	bacterial	bacterial	JJ
cord-322904-9mta0aem	124	16	toxins	toxin	NNS
cord-322904-9mta0aem	124	17	of	of	IN
cord-322904-9mta0aem	124	18	the	the	DT
cord-322904-9mta0aem	124	19	AB	AB	NNP
cord-322904-9mta0aem	124	20	5	5	CD
cord-322904-9mta0aem	124	21	family	family	NN
cord-322904-9mta0aem	124	22	,	,	,
cord-322904-9mta0aem	124	23	such	such	JJ
cord-322904-9mta0aem	124	24	as	as	IN
cord-322904-9mta0aem	124	25	cholera	cholera	NN
cord-322904-9mta0aem	124	26	toxin	toxin	NN
cord-322904-9mta0aem	124	27	,	,	,
cord-322904-9mta0aem	124	28	whose	whose	WP$
cord-322904-9mta0aem	124	29	known	know	VBN
cord-322904-9mta0aem	124	30	receptors	receptor	NNS
cord-322904-9mta0aem	124	31	are	be	VBP
cord-322904-9mta0aem	124	32	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	124	33	.	.	.
cord-322904-9mta0aem	125	1	In	in	IN
cord-322904-9mta0aem	125	2	the	the	DT
cord-322904-9mta0aem	125	3	case	case	NN
cord-322904-9mta0aem	125	4	of	of	IN
cord-322904-9mta0aem	125	5	the	the	DT
cord-322904-9mta0aem	125	6	toxins	toxin	NNS
cord-322904-9mta0aem	125	7	,	,	,
cord-322904-9mta0aem	125	8	however	however	RB
cord-322904-9mta0aem	125	9	,	,	,
cord-322904-9mta0aem	125	10	trafficking	trafficking	NN
cord-322904-9mta0aem	125	11	proceeds	proceed	NNS
cord-322904-9mta0aem	125	12	through	through	IN
cord-322904-9mta0aem	125	13	the	the	DT
cord-322904-9mta0aem	125	14	Golgi	Golgi	NNP
cord-322904-9mta0aem	125	15	.	.	.
cord-322904-9mta0aem	126	1	Thus	thus	RB
cord-322904-9mta0aem	126	2	far	far	RB
cord-322904-9mta0aem	126	3	there	there	EX
cord-322904-9mta0aem	126	4	is	be	VBZ
cord-322904-9mta0aem	126	5	no	no	DT
cord-322904-9mta0aem	126	6	evidence	evidence	NN
cord-322904-9mta0aem	126	7	that	that	IN
cord-322904-9mta0aem	126	8	mPyV	mPyV	NNP
cord-322904-9mta0aem	126	9	or	or	CC
cord-322904-9mta0aem	126	10	SV40	SV40	NNP
cord-322904-9mta0aem	126	11	traffics	traffic	VBZ
cord-322904-9mta0aem	126	12	through	through	IN
cord-322904-9mta0aem	126	13	the	the	DT
cord-322904-9mta0aem	126	14	Golgi	Golgi	NNP
cord-322904-9mta0aem	126	15	and	and	CC
cord-322904-9mta0aem	127	1	instead	instead	RB
cord-322904-9mta0aem	127	2	they	-PRON-	PRP
cord-322904-9mta0aem	127	3	appear	appear	VBP
cord-322904-9mta0aem	127	4	to	to	IN
cord-322904-9mta0aem	127	5	traffic	traffic	NN
cord-322904-9mta0aem	127	6	through	through	IN
cord-322904-9mta0aem	127	7	caveosomes	caveosome	NNS
cord-322904-9mta0aem	127	8	to	to	TO
cord-322904-9mta0aem	127	9	eventually	eventually	RB
cord-322904-9mta0aem	127	10	reach	reach	VB
cord-322904-9mta0aem	127	11	the	the	DT
cord-322904-9mta0aem	127	12	ER	er	NN
cord-322904-9mta0aem	127	13	where	where	WRB
cord-322904-9mta0aem	127	14	partial	partial	JJ
cord-322904-9mta0aem	127	15	uncoating	uncoating	NN
cord-322904-9mta0aem	127	16	of	of	IN
cord-322904-9mta0aem	127	17	the	the	DT
cord-322904-9mta0aem	127	18	viruses	virus	NNS
cord-322904-9mta0aem	127	19	take	take	VBP
cord-322904-9mta0aem	127	20	place	place	NN
cord-322904-9mta0aem	127	21	.	.	.
cord-322904-9mta0aem	128	1	Once	once	IN
cord-322904-9mta0aem	128	2	the	the	DT
cord-322904-9mta0aem	128	3	mPyV	mpyv	NN
cord-322904-9mta0aem	128	4	reaches	reach	VBZ
cord-322904-9mta0aem	128	5	the	the	DT
cord-322904-9mta0aem	128	6	ER	er	NN
cord-322904-9mta0aem	128	7	it	-PRON-	PRP
cord-322904-9mta0aem	128	8	takes	take	VBZ
cord-322904-9mta0aem	128	9	advantage	advantage	NN
cord-322904-9mta0aem	128	10	of	of	IN
cord-322904-9mta0aem	128	11	an	an	DT
cord-322904-9mta0aem	128	12	unusual	unusual	JJ
cord-322904-9mta0aem	128	13	member	member	NN
cord-322904-9mta0aem	128	14	of	of	IN
cord-322904-9mta0aem	128	15	the	the	DT
cord-322904-9mta0aem	128	16	protein	protein	NN
cord-322904-9mta0aem	128	17	disulfide	disulfide	NN
cord-322904-9mta0aem	128	18	isomerase	isomerase	NN
cord-322904-9mta0aem	128	19	family	family	NN
cord-322904-9mta0aem	128	20	,	,	,
cord-322904-9mta0aem	128	21	ERp29	ERp29	NNP
cord-322904-9mta0aem	128	22	(	(	-LRB-
cord-322904-9mta0aem	128	23	Magnuson	Magnuson	NNP
cord-322904-9mta0aem	128	24	et	et	NNP
cord-322904-9mta0aem	128	25	al	al	NNP
cord-322904-9mta0aem	128	26	.	.	NNP
cord-322904-9mta0aem	128	27	,	,	,
cord-322904-9mta0aem	128	28	2005	2005	CD
cord-322904-9mta0aem	128	29	)	)	-RRB-
cord-322904-9mta0aem	129	1	(	(	-LRB-
cord-322904-9mta0aem	129	2	Fig	Fig	NNP
cord-322904-9mta0aem	129	3	.	.	NNP
cord-322904-9mta0aem	129	4	2	2	CD
cord-322904-9mta0aem	129	5	)	)	-RRB-
cord-322904-9mta0aem	129	6	.	.	.
cord-322904-9mta0aem	130	1	PDI	PDI	NNP
cord-322904-9mta0aem	130	2	family	family	NN
cord-322904-9mta0aem	130	3	members	member	NNS
cord-322904-9mta0aem	130	4	are	be	VBP
cord-322904-9mta0aem	130	5	oxidoreductases	oxidoreductase	NNS
cord-322904-9mta0aem	130	6	that	that	WDT
cord-322904-9mta0aem	130	7	contain	contain	VBP
cord-322904-9mta0aem	130	8	one	one	CD
cord-322904-9mta0aem	130	9	to	to	IN
cord-322904-9mta0aem	130	10	several	several	JJ
cord-322904-9mta0aem	130	11	CXXC	CXXC	NNP
cord-322904-9mta0aem	130	12	motifs	motif	NNS
cord-322904-9mta0aem	130	13	in	in	IN
cord-322904-9mta0aem	130	14	their	-PRON-	PRP$
cord-322904-9mta0aem	130	15	thioredoxin	thioredoxin	NN
cord-322904-9mta0aem	130	16	domains	domain	NNS
cord-322904-9mta0aem	130	17	(	(	-LRB-
cord-322904-9mta0aem	130	18	Hebert	Hebert	NNP
cord-322904-9mta0aem	130	19	and	and	CC
cord-322904-9mta0aem	130	20	Molinari	Molinari	NNP
cord-322904-9mta0aem	130	21	,	,	,
cord-322904-9mta0aem	130	22	2007	2007	CD
cord-322904-9mta0aem	130	23	)	)	-RRB-
cord-322904-9mta0aem	130	24	.	.	.
cord-322904-9mta0aem	131	1	They	-PRON-	PRP
cord-322904-9mta0aem	131	2	function	function	VBP
cord-322904-9mta0aem	131	3	to	to	IN
cord-322904-9mta0aem	131	4	both	both	DT
cord-322904-9mta0aem	131	5	reduce	reduce	VB
cord-322904-9mta0aem	131	6	and	and	CC
cord-322904-9mta0aem	131	7	oxidize	oxidize	VB
cord-322904-9mta0aem	131	8	disulphide	disulphide	JJ
cord-322904-9mta0aem	131	9	bonds	bond	NNS
cord-322904-9mta0aem	131	10	in	in	IN
cord-322904-9mta0aem	131	11	newly	newly	RB
cord-322904-9mta0aem	131	12	synthesized	synthesize	VBN
cord-322904-9mta0aem	131	13	proteins	protein	NNS
cord-322904-9mta0aem	131	14	.	.	.
cord-322904-9mta0aem	132	1	They	-PRON-	PRP
cord-322904-9mta0aem	132	2	also	also	RB
cord-322904-9mta0aem	132	3	isomerize	isomerize	VBP
cord-322904-9mta0aem	132	4	disulphide	disulphide	JJ
cord-322904-9mta0aem	132	5	bonds	bond	NNS
cord-322904-9mta0aem	132	6	assisting	assist	VBG
cord-322904-9mta0aem	132	7	in	in	IN
cord-322904-9mta0aem	132	8	the	the	DT
cord-322904-9mta0aem	132	9	formation	formation	NN
cord-322904-9mta0aem	132	10	of	of	IN
cord-322904-9mta0aem	132	11	native	native	JJ
cord-322904-9mta0aem	132	12	protein	protein	NN
cord-322904-9mta0aem	132	13	structures	structure	NNS
cord-322904-9mta0aem	132	14	.	.	.
cord-322904-9mta0aem	133	1	ERp29	ERp29	NNP
cord-322904-9mta0aem	133	2	is	be	VBZ
cord-322904-9mta0aem	133	3	structurally	structurally	RB
cord-322904-9mta0aem	133	4	related	relate	VBN
cord-322904-9mta0aem	133	5	to	to	IN
cord-322904-9mta0aem	133	6	PDI	PDI	NNP
cord-322904-9mta0aem	133	7	proteins	protein	NNS
cord-322904-9mta0aem	134	1	but	but	CC
cord-322904-9mta0aem	134	2	it	-PRON-	PRP
cord-322904-9mta0aem	134	3	contains	contain	VBZ
cord-322904-9mta0aem	134	4	only	only	RB
cord-322904-9mta0aem	134	5	a	a	DT
cord-322904-9mta0aem	134	6	single	single	JJ
cord-322904-9mta0aem	134	7	cysteine	cysteine	NN
cord-322904-9mta0aem	134	8	in	in	IN
cord-322904-9mta0aem	134	9	its	-PRON-	PRP$
cord-322904-9mta0aem	134	10	Fig	fig	NN
cord-322904-9mta0aem	134	11	.	.	.
cord-322904-9mta0aem	135	1	3	3	LS
cord-322904-9mta0aem	135	2	.	.	.
cord-322904-9mta0aem	136	1	Mechanisms	mechanism	NNS
cord-322904-9mta0aem	136	2	used	use	VBN
cord-322904-9mta0aem	136	3	by	by	IN
cord-322904-9mta0aem	136	4	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	136	5	to	to	TO
cord-322904-9mta0aem	136	6	exit	exit	VB
cord-322904-9mta0aem	136	7	the	the	DT
cord-322904-9mta0aem	136	8	ER	er	NN
cord-322904-9mta0aem	136	9	and	and	CC
cord-322904-9mta0aem	136	10	target	target	VB
cord-322904-9mta0aem	136	11	their	-PRON-	PRP$
cord-322904-9mta0aem	136	12	genomes	genome	NNS
cord-322904-9mta0aem	136	13	to	to	IN
cord-322904-9mta0aem	136	14	the	the	DT
cord-322904-9mta0aem	136	15	nucleus	nucleus	NN
cord-322904-9mta0aem	136	16	.	.	.
cord-322904-9mta0aem	137	1	The	the	DT
cord-322904-9mta0aem	137	2	mouse	mouse	NN
cord-322904-9mta0aem	137	3	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	137	4	and	and	CC
cord-322904-9mta0aem	137	5	SV40	SV40	NNP
cord-322904-9mta0aem	138	1	both	both	DT
cord-322904-9mta0aem	138	2	traffic	traffic	NN
cord-322904-9mta0aem	138	3	to	to	IN
cord-322904-9mta0aem	138	4	the	the	DT
cord-322904-9mta0aem	138	5	ER	er	NN
cord-322904-9mta0aem	139	1	and	and	CC
cord-322904-9mta0aem	139	2	it	-PRON-	PRP
cord-322904-9mta0aem	139	3	is	be	VBZ
cord-322904-9mta0aem	139	4	presumed	presume	VBN
cord-322904-9mta0aem	139	5	but	but	CC
cord-322904-9mta0aem	139	6	not	not	RB
cord-322904-9mta0aem	139	7	formally	formally	RB
cord-322904-9mta0aem	139	8	proven	prove	VBN
cord-322904-9mta0aem	139	9	that	that	IN
cord-322904-9mta0aem	139	10	JCV	JCV	NNP
cord-322904-9mta0aem	139	11	and	and	CC
cord-322904-9mta0aem	139	12	BKV	BKV	NNP
cord-322904-9mta0aem	139	13	do	do	VBP
cord-322904-9mta0aem	139	14	the	the	DT
cord-322904-9mta0aem	139	15	same	same	JJ
cord-322904-9mta0aem	139	16	.	.	.
cord-322904-9mta0aem	140	1	Once	once	RB
cord-322904-9mta0aem	140	2	in	in	IN
cord-322904-9mta0aem	140	3	the	the	DT
cord-322904-9mta0aem	140	4	ER	ER	NNP
cord-322904-9mta0aem	140	5	mPyV	mPyV	NNP
cord-322904-9mta0aem	140	6	utilizes	utilize	VBZ
cord-322904-9mta0aem	140	7	the	the	DT
cord-322904-9mta0aem	140	8	unusual	unusual	JJ
cord-322904-9mta0aem	140	9	PDI	PDI	NNP
cord-322904-9mta0aem	140	10	family	family	NN
cord-322904-9mta0aem	140	11	member	member	NN
cord-322904-9mta0aem	140	12	,	,	,
cord-322904-9mta0aem	140	13	ERp29	ERp29	VBZ
cord-322904-9mta0aem	140	14	to	to	TO
cord-322904-9mta0aem	140	15	induce	induce	VB
cord-322904-9mta0aem	140	16	a	a	DT
cord-322904-9mta0aem	140	17	conformational	conformational	JJ
cord-322904-9mta0aem	140	18	change	change	NN
cord-322904-9mta0aem	140	19	in	in	IN
cord-322904-9mta0aem	140	20	its	-PRON-	PRP$
cord-322904-9mta0aem	140	21	coat	coat	NN
cord-322904-9mta0aem	140	22	protein	protein	NN
cord-322904-9mta0aem	140	23	.	.	.
cord-322904-9mta0aem	141	1	This	this	DT
cord-322904-9mta0aem	141	2	may	may	MD
cord-322904-9mta0aem	141	3	lead	lead	VB
cord-322904-9mta0aem	141	4	to	to	IN
cord-322904-9mta0aem	141	5	cleavage	cleavage	NN
cord-322904-9mta0aem	141	6	of	of	IN
cord-322904-9mta0aem	141	7	the	the	DT
cord-322904-9mta0aem	141	8	C	C	NNP
cord-322904-9mta0aem	141	9	-	-	HYPH
cord-322904-9mta0aem	141	10	terminal	terminal	NN
cord-322904-9mta0aem	141	11	arm	arm	NN
cord-322904-9mta0aem	141	12	of	of	IN
cord-322904-9mta0aem	141	13	VP1	VP1	NNP
cord-322904-9mta0aem	141	14	allowing	allow	VBG
cord-322904-9mta0aem	141	15	the	the	DT
cord-322904-9mta0aem	141	16	particle	particle	NN
cord-322904-9mta0aem	141	17	to	to	TO
cord-322904-9mta0aem	141	18	bind	bind	VB
cord-322904-9mta0aem	141	19	to	to	IN
cord-322904-9mta0aem	141	20	lipid	lipid	NN
cord-322904-9mta0aem	141	21	membranes	membrane	NNS
cord-322904-9mta0aem	141	22	.	.	.
cord-322904-9mta0aem	142	1	The	the	DT
cord-322904-9mta0aem	142	2	ER	ER	NNP
cord-322904-9mta0aem	142	3	retrotranslocation	retrotranslocation	NN
cord-322904-9mta0aem	142	4	protein	protein	NN
cord-322904-9mta0aem	142	5	Derlin	Derlin	NNP
cord-322904-9mta0aem	142	6	2	2	CD
cord-322904-9mta0aem	142	7	is	be	VBZ
cord-322904-9mta0aem	142	8	involved	involve	VBN
cord-322904-9mta0aem	142	9	in	in	IN
cord-322904-9mta0aem	142	10	ER	ER	NNP
cord-322904-9mta0aem	142	11	exit	exit	NN
cord-322904-9mta0aem	142	12	.	.	.
cord-322904-9mta0aem	143	1	SV40	SV40	NNP
cord-322904-9mta0aem	143	2	utilizes	utilize	VBZ
cord-322904-9mta0aem	143	3	the	the	DT
cord-322904-9mta0aem	143	4	canonical	canonical	JJ
cord-322904-9mta0aem	143	5	ER	ER	NNP
cord-322904-9mta0aem	143	6	oxidoreductases	oxidoreductase	NNS
cord-322904-9mta0aem	143	7	,	,	,
cord-322904-9mta0aem	143	8	PDI	PDI	NNP
cord-322904-9mta0aem	143	9	,	,	,
cord-322904-9mta0aem	143	10	and	and	CC
cord-322904-9mta0aem	143	11	ERp57	ERp57	NNS
cord-322904-9mta0aem	143	12	,	,	,
cord-322904-9mta0aem	143	13	to	to	TO
cord-322904-9mta0aem	143	14	unravel	unravel	VB
cord-322904-9mta0aem	143	15	12	12	CD
cord-322904-9mta0aem	143	16	of	of	IN
cord-322904-9mta0aem	143	17	the	the	DT
cord-322904-9mta0aem	143	18	vertex	vertex	NN
cord-322904-9mta0aem	143	19	pentamers	pentamer	NNS
cord-322904-9mta0aem	143	20	in	in	IN
cord-322904-9mta0aem	143	21	the	the	DT
cord-322904-9mta0aem	143	22	virus	virus	NN
cord-322904-9mta0aem	143	23	shell	shell	NN
cord-322904-9mta0aem	143	24	.	.	.
cord-322904-9mta0aem	144	1	This	this	DT
cord-322904-9mta0aem	144	2	unfolded	unfold	VBD
cord-322904-9mta0aem	145	1	protein	protein	NN
cord-322904-9mta0aem	145	2	is	be	VBZ
cord-322904-9mta0aem	145	3	then	then	RB
cord-322904-9mta0aem	145	4	recognized	recognize	VBN
cord-322904-9mta0aem	145	5	by	by	IN
cord-322904-9mta0aem	145	6	components	component	NNS
cord-322904-9mta0aem	145	7	of	of	IN
cord-322904-9mta0aem	145	8	the	the	DT
cord-322904-9mta0aem	145	9	ER	ER	NNP
cord-322904-9mta0aem	145	10	associated	associate	VBN
cord-322904-9mta0aem	145	11	degradation	degradation	NN
cord-322904-9mta0aem	145	12	(	(	-LRB-
cord-322904-9mta0aem	145	13	ERAD	ERAD	NNP
cord-322904-9mta0aem	145	14	)	)	-RRB-
cord-322904-9mta0aem	145	15	pathway	pathway	NN
cord-322904-9mta0aem	145	16	(	(	-LRB-
cord-322904-9mta0aem	145	17	Derlin	Derlin	NNP
cord-322904-9mta0aem	145	18	1	1	CD
cord-322904-9mta0aem	145	19	and	and	CC
cord-322904-9mta0aem	145	20	SelL1	SelL1	NNP
cord-322904-9mta0aem	145	21	)	)	-RRB-
cord-322904-9mta0aem	145	22	to	to	TO
cord-322904-9mta0aem	145	23	exit	exit	VB
cord-322904-9mta0aem	145	24	the	the	DT
cord-322904-9mta0aem	145	25	ER	er	NN
cord-322904-9mta0aem	145	26	.	.	.
cord-322904-9mta0aem	146	1	The	the	DT
cord-322904-9mta0aem	146	2	viruses	virus	NNS
cord-322904-9mta0aem	146	3	encounter	encounter	VBP
cord-322904-9mta0aem	146	4	a	a	DT
cord-322904-9mta0aem	146	5	low	low	JJ
cord-322904-9mta0aem	146	6	calcium	calcium	NN
cord-322904-9mta0aem	146	7	environment	environment	NN
cord-322904-9mta0aem	146	8	in	in	IN
cord-322904-9mta0aem	146	9	the	the	DT
cord-322904-9mta0aem	146	10	cytosol	cytosol	NN
cord-322904-9mta0aem	146	11	that	that	WDT
cord-322904-9mta0aem	146	12	may	may	MD
cord-322904-9mta0aem	146	13	allow	allow	VB
cord-322904-9mta0aem	146	14	for	for	IN
cord-322904-9mta0aem	146	15	their	-PRON-	PRP$
cord-322904-9mta0aem	146	16	further	further	JJ
cord-322904-9mta0aem	146	17	disassembly	disassembly	NN
cord-322904-9mta0aem	146	18	.	.	.
cord-322904-9mta0aem	147	1	Once	once	RB
cord-322904-9mta0aem	147	2	disassembled	disassemble	VBN
cord-322904-9mta0aem	147	3	the	the	DT
cord-322904-9mta0aem	147	4	viral	viral	JJ
cord-322904-9mta0aem	147	5	protein	protein	NN
cord-322904-9mta0aem	147	6	-	-	HYPH
cord-322904-9mta0aem	147	7	mini	mini	NN
cord-322904-9mta0aem	147	8	-	-	NN
cord-322904-9mta0aem	147	9	chromosome	chromosome	NN
cord-322904-9mta0aem	147	10	complex	complex	NN
cord-322904-9mta0aem	147	11	is	be	VBZ
cord-322904-9mta0aem	147	12	transported	transport	VBN
cord-322904-9mta0aem	147	13	across	across	IN
cord-322904-9mta0aem	147	14	an	an	DT
cord-322904-9mta0aem	147	15	intact	intact	JJ
cord-322904-9mta0aem	147	16	nuclear	nuclear	JJ
cord-322904-9mta0aem	147	17	pore	pore	NN
cord-322904-9mta0aem	147	18	for	for	IN
cord-322904-9mta0aem	147	19	genome	genome	NN
cord-322904-9mta0aem	147	20	delivery	delivery	NN
cord-322904-9mta0aem	147	21	to	to	IN
cord-322904-9mta0aem	147	22	the	the	DT
cord-322904-9mta0aem	147	23	nucleus	nucleus	NN
cord-322904-9mta0aem	147	24	.	.	.
cord-322904-9mta0aem	148	1	entire	entire	JJ
cord-322904-9mta0aem	148	2	sequence	sequence	NN
cord-322904-9mta0aem	148	3	and	and	CC
cord-322904-9mta0aem	148	4	hence	hence	RB
cord-322904-9mta0aem	148	5	can	can	MD
cord-322904-9mta0aem	148	6	only	only	RB
cord-322904-9mta0aem	148	7	function	function	VB
cord-322904-9mta0aem	148	8	in	in	IN
cord-322904-9mta0aem	148	9	the	the	DT
cord-322904-9mta0aem	148	10	isomerization	isomerization	NN
cord-322904-9mta0aem	148	11	reaction	reaction	NN
cord-322904-9mta0aem	148	12	.	.	.
cord-322904-9mta0aem	149	1	A	a	DT
cord-322904-9mta0aem	149	2	role	role	NN
cord-322904-9mta0aem	149	3	for	for	IN
cord-322904-9mta0aem	149	4	ERp29	ERp29	NNS
cord-322904-9mta0aem	149	5	in	in	IN
cord-322904-9mta0aem	149	6	normal	normal	JJ
cord-322904-9mta0aem	149	7	cellular	cellular	JJ
cord-322904-9mta0aem	149	8	functions	function	NNS
cord-322904-9mta0aem	149	9	has	have	VBZ
cord-322904-9mta0aem	149	10	not	not	RB
cord-322904-9mta0aem	149	11	been	be	VBN
cord-322904-9mta0aem	149	12	established	establish	VBN
cord-322904-9mta0aem	149	13	.	.	.
cord-322904-9mta0aem	150	1	The	the	DT
cord-322904-9mta0aem	150	2	Tsai	Tsai	NNP
cord-322904-9mta0aem	150	3	group	group	NN
cord-322904-9mta0aem	150	4	identified	identify	VBD
cord-322904-9mta0aem	150	5	ERp29	ERp29	NNS
cord-322904-9mta0aem	150	6	as	as	IN
cord-322904-9mta0aem	150	7	the	the	DT
cord-322904-9mta0aem	150	8	PDI	PDI	NNP
cord-322904-9mta0aem	150	9	family	family	NN
cord-322904-9mta0aem	150	10	member	member	NN
cord-322904-9mta0aem	150	11	responsible	responsible	JJ
cord-322904-9mta0aem	150	12	for	for	IN
cord-322904-9mta0aem	150	13	inducing	induce	VBG
cord-322904-9mta0aem	150	14	a	a	DT
cord-322904-9mta0aem	150	15	conformational	conformational	JJ
cord-322904-9mta0aem	150	16	change	change	NN
cord-322904-9mta0aem	150	17	in	in	IN
cord-322904-9mta0aem	150	18	mPyV	mpyv	JJ
cord-322904-9mta0aem	150	19	VP1	vp1	NN
cord-322904-9mta0aem	150	20	that	that	WDT
cord-322904-9mta0aem	150	21	exposes	expose	VBZ
cord-322904-9mta0aem	150	22	a	a	DT
cord-322904-9mta0aem	150	23	trypsin	trypsin	NN
cord-322904-9mta0aem	150	24	sensitive	sensitive	JJ
cord-322904-9mta0aem	150	25	site	site	NN
cord-322904-9mta0aem	150	26	in	in	IN
cord-322904-9mta0aem	150	27	VP1	VP1	NNP
cord-322904-9mta0aem	151	1	(	(	-LRB-
cord-322904-9mta0aem	151	2	Tsai	Tsai	NNP
cord-322904-9mta0aem	151	3	et	et	NNP
cord-322904-9mta0aem	151	4	al	al	NNP
cord-322904-9mta0aem	151	5	.	.	NNP
cord-322904-9mta0aem	151	6	,	,	,
cord-322904-9mta0aem	151	7	2003	2003	CD
cord-322904-9mta0aem	151	8	)	)	-RRB-
cord-322904-9mta0aem	152	1	(	(	-LRB-
cord-322904-9mta0aem	152	2	Fig	Fig	NNP
cord-322904-9mta0aem	152	3	.	.	.
cord-322904-9mta0aem	152	4	3	3	CD
cord-322904-9mta0aem	152	5	)	)	-RRB-
cord-322904-9mta0aem	152	6	.	.	.
cord-322904-9mta0aem	153	1	This	this	DT
cord-322904-9mta0aem	153	2	conformational	conformational	JJ
cord-322904-9mta0aem	153	3	change	change	NN
cord-322904-9mta0aem	153	4	is	be	VBZ
cord-322904-9mta0aem	153	5	thought	think	VBN
cord-322904-9mta0aem	153	6	to	to	TO
cord-322904-9mta0aem	153	7	result	result	VB
cord-322904-9mta0aem	153	8	in	in	IN
cord-322904-9mta0aem	153	9	the	the	DT
cord-322904-9mta0aem	153	10	proteolytic	proteolytic	JJ
cord-322904-9mta0aem	153	11	cleavage	cleavage	NN
cord-322904-9mta0aem	153	12	of	of	IN
cord-322904-9mta0aem	153	13	the	the	DT
cord-322904-9mta0aem	153	14	C	C	NNP
cord-322904-9mta0aem	153	15	-	-	HYPH
cord-322904-9mta0aem	153	16	terminal	terminal	NN
cord-322904-9mta0aem	153	17	arm	arm	NN
cord-322904-9mta0aem	153	18	of	of	IN
cord-322904-9mta0aem	153	19	VP1	VP1	NNP
cord-322904-9mta0aem	153	20	.	.	.
cord-322904-9mta0aem	154	1	As	as	IN
cord-322904-9mta0aem	154	2	the	the	DT
cord-322904-9mta0aem	154	3	C	C	NNP
cord-322904-9mta0aem	154	4	-	-	HYPH
cord-322904-9mta0aem	154	5	terminal	terminal	NN
cord-322904-9mta0aem	154	6	arm	arm	NN
cord-322904-9mta0aem	154	7	is	be	VBZ
cord-322904-9mta0aem	154	8	involved	involve	VBN
cord-322904-9mta0aem	154	9	in	in	IN
cord-322904-9mta0aem	154	10	linking	link	VBG
cord-322904-9mta0aem	154	11	and	and	CC
cord-322904-9mta0aem	154	12	stabilizing	stabilize	VBG
cord-322904-9mta0aem	154	13	pentamer	pentamer	NNP
cord-322904-9mta0aem	154	14	-	-	HYPH
cord-322904-9mta0aem	154	15	pentamer	pentamer	NNP
cord-322904-9mta0aem	154	16	interactions	interaction	NNS
cord-322904-9mta0aem	154	17	its	-PRON-	PRP$
cord-322904-9mta0aem	154	18	cleavage	cleavage	NN
cord-322904-9mta0aem	154	19	would	would	MD
cord-322904-9mta0aem	154	20	be	be	VB
cord-322904-9mta0aem	154	21	predicted	predict	VBN
cord-322904-9mta0aem	154	22	to	to	TO
cord-322904-9mta0aem	154	23	destabilize	destabilize	VB
cord-322904-9mta0aem	154	24	the	the	DT
cord-322904-9mta0aem	154	25	particle	particle	NN
cord-322904-9mta0aem	154	26	.	.	.
cord-322904-9mta0aem	155	1	The	the	DT
cord-322904-9mta0aem	155	2	cleavage	cleavage	NN
cord-322904-9mta0aem	155	3	also	also	RB
cord-322904-9mta0aem	155	4	led	lead	VBD
cord-322904-9mta0aem	155	5	to	to	IN
cord-322904-9mta0aem	155	6	the	the	DT
cord-322904-9mta0aem	155	7	formation	formation	NN
cord-322904-9mta0aem	155	8	of	of	IN
cord-322904-9mta0aem	155	9	a	a	DT
cord-322904-9mta0aem	155	10	virion	virion	NN
cord-322904-9mta0aem	155	11	particle	particle	NN
cord-322904-9mta0aem	155	12	capable	capable	JJ
cord-322904-9mta0aem	155	13	of	of	IN
cord-322904-9mta0aem	155	14	binding	bind	VBG
cord-322904-9mta0aem	155	15	and	and	CC
cord-322904-9mta0aem	155	16	penetrating	penetrate	VBG
cord-322904-9mta0aem	155	17	a	a	DT
cord-322904-9mta0aem	155	18	lipid	lipid	NN
cord-322904-9mta0aem	155	19	bilayer	bilayer	NN
cord-322904-9mta0aem	155	20	.	.	.
cord-322904-9mta0aem	156	1	This	this	DT
cord-322904-9mta0aem	156	2	is	be	VBZ
cord-322904-9mta0aem	156	3	predicted	predict	VBN
cord-322904-9mta0aem	156	4	to	to	TO
cord-322904-9mta0aem	156	5	facilitate	facilitate	VB
cord-322904-9mta0aem	156	6	the	the	DT
cord-322904-9mta0aem	156	7	release	release	NN
cord-322904-9mta0aem	156	8	of	of	IN
cord-322904-9mta0aem	156	9	a	a	DT
cord-322904-9mta0aem	156	10	partially	partially	RB
cord-322904-9mta0aem	156	11	disassembled	disassemble	VBN
cord-322904-9mta0aem	156	12	and	and	CC
cord-322904-9mta0aem	156	13	de	de	JJ
cord-322904-9mta0aem	156	14	-	-	JJ
cord-322904-9mta0aem	156	15	stabilized	stabilize	VBN
cord-322904-9mta0aem	156	16	virion	virion	NN
cord-322904-9mta0aem	156	17	into	into	IN
cord-322904-9mta0aem	156	18	the	the	DT
cord-322904-9mta0aem	156	19	cytosol	cytosol	NN
cord-322904-9mta0aem	156	20	where	where	WRB
cord-322904-9mta0aem	156	21	nuclear	nuclear	JJ
cord-322904-9mta0aem	156	22	localization	localization	NN
cord-322904-9mta0aem	156	23	signals	signal	NNS
cord-322904-9mta0aem	156	24	in	in	IN
cord-322904-9mta0aem	156	25	the	the	DT
cord-322904-9mta0aem	156	26	VP1	VP1	NNP
cord-322904-9mta0aem	156	27	protein	protein	NN
cord-322904-9mta0aem	156	28	could	could	MD
cord-322904-9mta0aem	156	29	direct	direct	VB
cord-322904-9mta0aem	156	30	it	-PRON-	PRP
cord-322904-9mta0aem	156	31	across	across	IN
cord-322904-9mta0aem	156	32	the	the	DT
cord-322904-9mta0aem	156	33	nuclear	nuclear	JJ
cord-322904-9mta0aem	156	34	pore	pore	NN
cord-322904-9mta0aem	156	35	(	(	-LRB-
cord-322904-9mta0aem	156	36	Fig	Fig	NNP
cord-322904-9mta0aem	156	37	.	.	.
cord-322904-9mta0aem	156	38	3	3	CD
cord-322904-9mta0aem	156	39	)	)	-RRB-
cord-322904-9mta0aem	156	40	.	.	.
cord-322904-9mta0aem	157	1	Work	work	VB
cord-322904-9mta0aem	157	2	from	from	IN
cord-322904-9mta0aem	157	3	the	the	DT
cord-322904-9mta0aem	157	4	Benjamin	Benjamin	NNP
cord-322904-9mta0aem	157	5	lab	lab	NN
cord-322904-9mta0aem	157	6	identified	identify	VBD
cord-322904-9mta0aem	157	7	another	another	DT
cord-322904-9mta0aem	157	8	ER	ER	NNP
cord-322904-9mta0aem	157	9	protein	protein	NN
cord-322904-9mta0aem	157	10	as	as	IN
cord-322904-9mta0aem	157	11	being	be	VBG
cord-322904-9mta0aem	157	12	critical	critical	JJ
cord-322904-9mta0aem	157	13	for	for	IN
cord-322904-9mta0aem	157	14	mPyV	mpyv	JJ
cord-322904-9mta0aem	157	15	infection	infection	NN
cord-322904-9mta0aem	157	16	.	.	.
cord-322904-9mta0aem	158	1	In	in	IN
cord-322904-9mta0aem	158	2	this	this	DT
cord-322904-9mta0aem	158	3	study	study	NN
cord-322904-9mta0aem	158	4	shRNAs	shRNAs	NNP
cord-322904-9mta0aem	158	5	directed	direct	VBD
cord-322904-9mta0aem	158	6	at	at	IN
cord-322904-9mta0aem	158	7	a	a	DT
cord-322904-9mta0aem	158	8	protein	protein	NN
cord-322904-9mta0aem	158	9	involved	involve	VBN
cord-322904-9mta0aem	158	10	in	in	IN
cord-322904-9mta0aem	158	11	retrotranslocation	retrotranslocation	NN
cord-322904-9mta0aem	158	12	of	of	IN
cord-322904-9mta0aem	158	13	misfolded	misfolded	JJ
cord-322904-9mta0aem	158	14	proteins	protein	NNS
cord-322904-9mta0aem	158	15	out	out	IN
cord-322904-9mta0aem	158	16	of	of	IN
cord-322904-9mta0aem	158	17	the	the	DT
cord-322904-9mta0aem	158	18	ER	ER	NNP
cord-322904-9mta0aem	158	19	,	,	,
cord-322904-9mta0aem	158	20	Derlin	Derlin	NNP
cord-322904-9mta0aem	158	21	2	2	CD
cord-322904-9mta0aem	158	22	,	,	,
cord-322904-9mta0aem	158	23	was	be	VBD
cord-322904-9mta0aem	158	24	found	find	VBN
cord-322904-9mta0aem	158	25	to	to	TO
cord-322904-9mta0aem	158	26	significantly	significantly	RB
cord-322904-9mta0aem	158	27	impair	impair	VB
cord-322904-9mta0aem	158	28	mPyV	mpyv	JJ
cord-322904-9mta0aem	158	29	infection	infection	NN
cord-322904-9mta0aem	159	1	(	(	-LRB-
cord-322904-9mta0aem	159	2	Lilley	Lilley	NNP
cord-322904-9mta0aem	159	3	et	et	NNP
cord-322904-9mta0aem	159	4	al	al	NNP
cord-322904-9mta0aem	159	5	.	.	NNP
cord-322904-9mta0aem	159	6	,	,	,
cord-322904-9mta0aem	159	7	2006	2006	CD
cord-322904-9mta0aem	159	8	)	)	-RRB-
cord-322904-9mta0aem	160	1	(	(	-LRB-
cord-322904-9mta0aem	160	2	Fig	Fig	NNP
cord-322904-9mta0aem	160	3	.	.	.
cord-322904-9mta0aem	160	4	3	3	CD
cord-322904-9mta0aem	160	5	)	)	-RRB-
cord-322904-9mta0aem	160	6	.	.	.
cord-322904-9mta0aem	161	1	In	in	IN
cord-322904-9mta0aem	161	2	related	related	JJ
cord-322904-9mta0aem	161	3	work	work	NN
cord-322904-9mta0aem	161	4	Helenius	Helenius	NNP
cord-322904-9mta0aem	161	5	and	and	CC
cord-322904-9mta0aem	161	6	colleagues	colleague	NNS
cord-322904-9mta0aem	161	7	found	find	VBD
cord-322904-9mta0aem	161	8	that	that	IN
cord-322904-9mta0aem	161	9	several	several	JJ
cord-322904-9mta0aem	161	10	ER	ER	NNP
cord-322904-9mta0aem	161	11	associated	associate	VBN
cord-322904-9mta0aem	161	12	factors	factor	NNS
cord-322904-9mta0aem	161	13	played	play	VBD
cord-322904-9mta0aem	161	14	critical	critical	JJ
cord-322904-9mta0aem	161	15	roles	role	NNS
cord-322904-9mta0aem	161	16	in	in	IN
cord-322904-9mta0aem	161	17	SV40	SV40	NNP
cord-322904-9mta0aem	161	18	disassembly	disassembly	NN
cord-322904-9mta0aem	161	19	and	and	CC
cord-322904-9mta0aem	161	20	release	release	NN
cord-322904-9mta0aem	161	21	from	from	IN
cord-322904-9mta0aem	161	22	the	the	DT
cord-322904-9mta0aem	161	23	ER	ER	NNP
cord-322904-9mta0aem	161	24	(	(	-LRB-
cord-322904-9mta0aem	161	25	Schelhaas	Schelhaas	NNP
cord-322904-9mta0aem	161	26	et	et	FW
cord-322904-9mta0aem	161	27	al	al	NNP
cord-322904-9mta0aem	161	28	.	.	NNP
cord-322904-9mta0aem	161	29	,	,	,
cord-322904-9mta0aem	161	30	2007	2007	CD
cord-322904-9mta0aem	161	31	)	)	-RRB-
cord-322904-9mta0aem	162	1	(	(	-LRB-
cord-322904-9mta0aem	162	2	Fig	Fig	NNP
cord-322904-9mta0aem	162	3	.	.	.
cord-322904-9mta0aem	162	4	3	3	CD
cord-322904-9mta0aem	162	5	)	)	-RRB-
cord-322904-9mta0aem	162	6	.	.	.
cord-322904-9mta0aem	163	1	Inhibition	inhibition	NN
cord-322904-9mta0aem	163	2	of	of	IN
cord-322904-9mta0aem	163	3	PDI	PDI	NNP
cord-322904-9mta0aem	163	4	,	,	,
cord-322904-9mta0aem	163	5	ERp57	ERp57	NNS
cord-322904-9mta0aem	163	6	,	,	,
cord-322904-9mta0aem	163	7	and	and	CC
cord-322904-9mta0aem	163	8	Derlin	Derlin	NNP
cord-322904-9mta0aem	163	9	1	1	CD
cord-322904-9mta0aem	163	10	by	by	IN
cord-322904-9mta0aem	163	11	siRNA	siRNA	NNP
cord-322904-9mta0aem	163	12	knockdown	knockdown	NNP
cord-322904-9mta0aem	163	13	all	all	DT
cord-322904-9mta0aem	163	14	inhibited	inhibit	VBN
cord-322904-9mta0aem	163	15	SV40	SV40	NNP
cord-322904-9mta0aem	163	16	infection	infection	NN
cord-322904-9mta0aem	163	17	of	of	IN
cord-322904-9mta0aem	163	18	cells	cell	NNS
cord-322904-9mta0aem	163	19	.	.	.
cord-322904-9mta0aem	164	1	Knockdown	knockdown	NN
cord-322904-9mta0aem	164	2	of	of	IN
cord-322904-9mta0aem	164	3	ERp29	ERp29	NNS
cord-322904-9mta0aem	164	4	,	,	,
cord-322904-9mta0aem	164	5	calnexin	calnexin	NNP
cord-322904-9mta0aem	164	6	or	or	CC
cord-322904-9mta0aem	164	7	calreticulin	calreticulin	NNP
cord-322904-9mta0aem	164	8	had	have	VBD
cord-322904-9mta0aem	164	9	no	no	DT
cord-322904-9mta0aem	164	10	effect	effect	NN
cord-322904-9mta0aem	164	11	on	on	IN
cord-322904-9mta0aem	164	12	SV40	SV40	NNP
cord-322904-9mta0aem	164	13	infection	infection	NN
cord-322904-9mta0aem	164	14	.	.	.
cord-322904-9mta0aem	165	1	They	-PRON-	PRP
cord-322904-9mta0aem	165	2	found	find	VBD
cord-322904-9mta0aem	165	3	that	that	IN
cord-322904-9mta0aem	165	4	ERp57	ERp57	NNS
cord-322904-9mta0aem	165	5	uncoupled	uncouple	VBD
cord-322904-9mta0aem	165	6	the	the	DT
cord-322904-9mta0aem	165	7	12	12	CD
cord-322904-9mta0aem	165	8	five	five	CD
cord-322904-9mta0aem	165	9	-	-	HYPH
cord-322904-9mta0aem	165	10	coordinated	coordinate	VBN
cord-322904-9mta0aem	165	11	VP1	vp1	NN
cord-322904-9mta0aem	165	12	pentamers	pentamer	NNS
cord-322904-9mta0aem	165	13	of	of	IN
cord-322904-9mta0aem	165	14	SV40	SV40	NNP
cord-322904-9mta0aem	165	15	.	.	.
cord-322904-9mta0aem	166	1	This	this	DT
cord-322904-9mta0aem	166	2	led	lead	VBD
cord-322904-9mta0aem	166	3	to	to	TO
cord-322904-9mta0aem	166	4	complete	complete	VB
cord-322904-9mta0aem	166	5	uncoating	uncoating	NN
cord-322904-9mta0aem	166	6	in	in	IN
cord-322904-9mta0aem	166	7	the	the	DT
cord-322904-9mta0aem	166	8	presence	presence	NN
cord-322904-9mta0aem	166	9	of	of	IN
cord-322904-9mta0aem	166	10	EGTA	EGTA	NNP
cord-322904-9mta0aem	166	11	,	,	,
cord-322904-9mta0aem	166	12	which	which	WDT
cord-322904-9mta0aem	166	13	removes	remove	VBZ
cord-322904-9mta0aem	166	14	the	the	DT
cord-322904-9mta0aem	166	15	calcium	calcium	NN
cord-322904-9mta0aem	166	16	ions	ion	NNS
cord-322904-9mta0aem	166	17	that	that	WDT
cord-322904-9mta0aem	166	18	help	help	VBP
cord-322904-9mta0aem	166	19	to	to	TO
cord-322904-9mta0aem	166	20	anchor	anchor	VB
cord-322904-9mta0aem	166	21	the	the	DT
cord-322904-9mta0aem	166	22	incoming	incoming	JJ
cord-322904-9mta0aem	166	23	C	c	NN
cord-322904-9mta0aem	166	24	-	-	HYPH
cord-322904-9mta0aem	166	25	terminal	terminal	NN
cord-322904-9mta0aem	166	26	arms	arm	NNS
cord-322904-9mta0aem	166	27	.	.	.
cord-322904-9mta0aem	167	1	The	the	DT
cord-322904-9mta0aem	167	2	group	group	NN
cord-322904-9mta0aem	167	3	also	also	RB
cord-322904-9mta0aem	167	4	demonstrated	demonstrate	VBD
cord-322904-9mta0aem	167	5	a	a	DT
cord-322904-9mta0aem	167	6	role	role	NN
cord-322904-9mta0aem	167	7	for	for	IN
cord-322904-9mta0aem	167	8	Derlin	Derlin	NNP
cord-322904-9mta0aem	167	9	1	1	CD
cord-322904-9mta0aem	167	10	and	and	CC
cord-322904-9mta0aem	167	11	SelL1	SelL1	NNP
cord-322904-9mta0aem	167	12	,	,	,
cord-322904-9mta0aem	167	13	two	two	CD
cord-322904-9mta0aem	167	14	proteins	protein	NNS
cord-322904-9mta0aem	167	15	involved	involve	VBN
cord-322904-9mta0aem	167	16	in	in	IN
cord-322904-9mta0aem	167	17	the	the	DT
cord-322904-9mta0aem	167	18	ERAD	ERAD	NNP
cord-322904-9mta0aem	167	19	retrotranslocation	retrotranslocation	NN
cord-322904-9mta0aem	167	20	pathway	pathway	NN
cord-322904-9mta0aem	167	21	in	in	IN
cord-322904-9mta0aem	167	22	SV40	SV40	NNP
cord-322904-9mta0aem	167	23	infection	infection	NN
cord-322904-9mta0aem	168	1	(	(	-LRB-
cord-322904-9mta0aem	168	2	Fig	Fig	NNP
cord-322904-9mta0aem	168	3	.	.	.
cord-322904-9mta0aem	168	4	3	3	CD
cord-322904-9mta0aem	168	5	)	)	-RRB-
cord-322904-9mta0aem	168	6	.	.	.
cord-322904-9mta0aem	169	1	The	the	DT
cord-322904-9mta0aem	169	2	model	model	NN
cord-322904-9mta0aem	169	3	that	that	WDT
cord-322904-9mta0aem	169	4	emerges	emerge	VBZ
cord-322904-9mta0aem	169	5	is	be	VBZ
cord-322904-9mta0aem	169	6	one	one	CD
cord-322904-9mta0aem	169	7	where	where	WRB
cord-322904-9mta0aem	169	8	the	the	DT
cord-322904-9mta0aem	169	9	virion	virion	NN
cord-322904-9mta0aem	169	10	is	be	VBZ
cord-322904-9mta0aem	169	11	delivered	deliver	VBN
cord-322904-9mta0aem	169	12	to	to	IN
cord-322904-9mta0aem	169	13	the	the	DT
cord-322904-9mta0aem	169	14	ER	ER	NNP
cord-322904-9mta0aem	169	15	where	where	WRB
cord-322904-9mta0aem	169	16	it	-PRON-	PRP
cord-322904-9mta0aem	169	17	is	be	VBZ
cord-322904-9mta0aem	169	18	recognized	recognize	VBN
cord-322904-9mta0aem	169	19	by	by	IN
cord-322904-9mta0aem	169	20	components	component	NNS
cord-322904-9mta0aem	169	21	of	of	IN
cord-322904-9mta0aem	169	22	the	the	DT
cord-322904-9mta0aem	169	23	ER	ER	NNP
cord-322904-9mta0aem	169	24	quality	quality	NN
cord-322904-9mta0aem	169	25	control	control	NN
cord-322904-9mta0aem	169	26	machinery	machinery	NN
cord-322904-9mta0aem	169	27	and	and	CC
cord-322904-9mta0aem	169	28	is	be	VBZ
cord-322904-9mta0aem	169	29	subjected	subject	VBN
cord-322904-9mta0aem	169	30	to	to	IN
cord-322904-9mta0aem	169	31	PDI	PDI	NNP
cord-322904-9mta0aem	169	32	related	related	JJ
cord-322904-9mta0aem	169	33	proteins	protein	NNS
cord-322904-9mta0aem	169	34	that	that	WDT
cord-322904-9mta0aem	169	35	isomerize	isomerize	VBP
cord-322904-9mta0aem	169	36	specific	specific	JJ
cord-322904-9mta0aem	169	37	disulfide	disulfide	JJ
cord-322904-9mta0aem	169	38	bonds	bond	NNS
cord-322904-9mta0aem	169	39	involved	involve	VBN
cord-322904-9mta0aem	169	40	in	in	IN
cord-322904-9mta0aem	169	41	linking	link	VBG
cord-322904-9mta0aem	169	42	pentamers	pentamer	NNS
cord-322904-9mta0aem	169	43	together	together	RB
cord-322904-9mta0aem	169	44	within	within	IN
cord-322904-9mta0aem	169	45	the	the	DT
cord-322904-9mta0aem	169	46	capsid	capsid	NN
cord-322904-9mta0aem	169	47	.	.	.
cord-322904-9mta0aem	170	1	The	the	DT
cord-322904-9mta0aem	170	2	destabilized	destabilized	JJ
cord-322904-9mta0aem	170	3	virion	virion	NN
cord-322904-9mta0aem	170	4	is	be	VBZ
cord-322904-9mta0aem	170	5	then	then	RB
cord-322904-9mta0aem	170	6	recognized	recognize	VBN
cord-322904-9mta0aem	170	7	essentially	essentially	RB
cord-322904-9mta0aem	170	8	as	as	IN
cord-322904-9mta0aem	170	9	a	a	DT
cord-322904-9mta0aem	170	10	misfolded	misfolde	VBN
cord-322904-9mta0aem	170	11	protein	protein	NN
cord-322904-9mta0aem	170	12	and	and	CC
cord-322904-9mta0aem	170	13	is	be	VBZ
cord-322904-9mta0aem	170	14	retrotranslocated	retrotranslocate	VBN
cord-322904-9mta0aem	170	15	out	out	IN
cord-322904-9mta0aem	170	16	of	of	IN
cord-322904-9mta0aem	170	17	the	the	DT
cord-322904-9mta0aem	170	18	ER	ER	NNP
cord-322904-9mta0aem	170	19	where	where	WRB
cord-322904-9mta0aem	170	20	it	-PRON-	PRP
cord-322904-9mta0aem	170	21	encounters	encounter	VBZ
cord-322904-9mta0aem	170	22	a	a	DT
cord-322904-9mta0aem	170	23	low	low	JJ
cord-322904-9mta0aem	170	24	calcium	calcium	NN
cord-322904-9mta0aem	170	25	environment	environment	NN
cord-322904-9mta0aem	170	26	in	in	IN
cord-322904-9mta0aem	170	27	the	the	DT
cord-322904-9mta0aem	170	28	cytosol	cytosol	NN
cord-322904-9mta0aem	170	29	.	.	.
cord-322904-9mta0aem	171	1	Calcium	calcium	NN
cord-322904-9mta0aem	171	2	is	be	VBZ
cord-322904-9mta0aem	171	3	critical	critical	JJ
cord-322904-9mta0aem	171	4	for	for	IN
cord-322904-9mta0aem	171	5	viral	viral	JJ
cord-322904-9mta0aem	171	6	particle	particle	NN
cord-322904-9mta0aem	171	7	stability	stability	NN
cord-322904-9mta0aem	171	8	and	and	CC
cord-322904-9mta0aem	171	9	low	low	JJ
cord-322904-9mta0aem	171	10	levels	level	NNS
cord-322904-9mta0aem	171	11	of	of	IN
cord-322904-9mta0aem	171	12	calcium	calcium	NN
cord-322904-9mta0aem	171	13	in	in	IN
cord-322904-9mta0aem	171	14	the	the	DT
cord-322904-9mta0aem	171	15	cytosol	cytosol	NN
cord-322904-9mta0aem	171	16	likely	likely	RB
cord-322904-9mta0aem	171	17	contribute	contribute	VBP
cord-322904-9mta0aem	171	18	to	to	IN
cord-322904-9mta0aem	171	19	further	further	JJ
cord-322904-9mta0aem	171	20	destabilization	destabilization	NN
cord-322904-9mta0aem	171	21	of	of	IN
cord-322904-9mta0aem	171	22	the	the	DT
cord-322904-9mta0aem	171	23	virion	virion	NN
cord-322904-9mta0aem	171	24	.	.	.
cord-322904-9mta0aem	172	1	Exposure	exposure	NN
cord-322904-9mta0aem	172	2	of	of	IN
cord-322904-9mta0aem	172	3	nuclearlocalization	nuclearlocalization	NN
cord-322904-9mta0aem	172	4	signals	signal	NNS
cord-322904-9mta0aem	172	5	in	in	IN
cord-322904-9mta0aem	172	6	viral	viral	JJ
cord-322904-9mta0aem	172	7	capsid	capsid	NN
cord-322904-9mta0aem	172	8	proteins	protein	NNS
cord-322904-9mta0aem	172	9	that	that	WDT
cord-322904-9mta0aem	172	10	likely	likely	RB
cord-322904-9mta0aem	172	11	remain	remain	VBP
cord-322904-9mta0aem	172	12	bound	bind	VBN
cord-322904-9mta0aem	172	13	to	to	IN
cord-322904-9mta0aem	172	14	the	the	DT
cord-322904-9mta0aem	172	15	mini	mini	NN
cord-322904-9mta0aem	172	16	-	-	NN
cord-322904-9mta0aem	172	17	chromosome	chromosome	NN
cord-322904-9mta0aem	172	18	then	then	RB
cord-322904-9mta0aem	172	19	transport	transport	VBP
cord-322904-9mta0aem	172	20	the	the	DT
cord-322904-9mta0aem	172	21	mini	mini	NN
cord-322904-9mta0aem	172	22	-	-	NN
cord-322904-9mta0aem	172	23	chromosome	chromosome	NN
cord-322904-9mta0aem	172	24	across	across	IN
cord-322904-9mta0aem	172	25	the	the	DT
cord-322904-9mta0aem	172	26	nuclear	nuclear	JJ
cord-322904-9mta0aem	172	27	pore	pore	NN
cord-322904-9mta0aem	172	28	(	(	-LRB-
cord-322904-9mta0aem	172	29	Ishii	Ishii	NNP
cord-322904-9mta0aem	172	30	et	et	NNP
cord-322904-9mta0aem	172	31	al	al	NNP
cord-322904-9mta0aem	172	32	.	.	.
cord-322904-9mta0aem	173	1	,	,	,
cord-322904-9mta0aem	173	2	1996	1996	CD
cord-322904-9mta0aem	173	3	;	;	:
cord-322904-9mta0aem	173	4	Kasamatsu	Kasamatsu	NNP
cord-322904-9mta0aem	173	5	and	and	CC
cord-322904-9mta0aem	173	6	Nakanishi	Nakanishi	NNP
cord-322904-9mta0aem	173	7	,	,	,
cord-322904-9mta0aem	173	8	1998	1998	CD
cord-322904-9mta0aem	173	9	;	;	:
cord-322904-9mta0aem	173	10	Nakanishi	Nakanishi	NNP
cord-322904-9mta0aem	173	11	et	et	NNP
cord-322904-9mta0aem	173	12	al	al	NNP
cord-322904-9mta0aem	173	13	.	.	NNP
cord-322904-9mta0aem	173	14	,	,	,
cord-322904-9mta0aem	173	15	1996	1996	CD
cord-322904-9mta0aem	173	16	;	;	:
cord-322904-9mta0aem	173	17	Yamada	Yamada	NNP
cord-322904-9mta0aem	173	18	and	and	CC
cord-322904-9mta0aem	173	19	Kasamatsu	Kasamatsu	NNP
cord-322904-9mta0aem	173	20	,	,	,
cord-322904-9mta0aem	173	21	1993	1993	CD
cord-322904-9mta0aem	173	22	)	)	-RRB-
cord-322904-9mta0aem	174	1	(	(	-LRB-
cord-322904-9mta0aem	174	2	Fig	Fig	NNP
cord-322904-9mta0aem	174	3	.	.	.
cord-322904-9mta0aem	174	4	3	3	CD
cord-322904-9mta0aem	174	5	)	)	-RRB-
cord-322904-9mta0aem	174	6	.	.	.
cord-322904-9mta0aem	175	1	It	-PRON-	PRP
cord-322904-9mta0aem	175	2	thus	thus	RB
cord-322904-9mta0aem	175	3	appears	appear	VBZ
cord-322904-9mta0aem	175	4	that	that	IN
cord-322904-9mta0aem	175	5	at	at	RB
cord-322904-9mta0aem	175	6	least	least	RBS
cord-322904-9mta0aem	175	7	two	two	CD
cord-322904-9mta0aem	175	8	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	175	9	,	,	,
cord-322904-9mta0aem	175	10	mPyV	mPyV	NNP
cord-322904-9mta0aem	175	11	and	and	CC
cord-322904-9mta0aem	175	12	SV40	SV40	NNP
cord-322904-9mta0aem	175	13	,	,	,
cord-322904-9mta0aem	175	14	utilize	utilize	VB
cord-322904-9mta0aem	175	15	ER	ER	NNP
cord-322904-9mta0aem	175	16	associated	associate	VBN
cord-322904-9mta0aem	175	17	degradative	degradative	JJ
cord-322904-9mta0aem	175	18	pathways	pathway	NNS
cord-322904-9mta0aem	175	19	for	for	IN
cord-322904-9mta0aem	175	20	uncoating	uncoating	NN
cord-322904-9mta0aem	175	21	.	.	.
cord-322904-9mta0aem	176	1	Studies	study	NNS
cord-322904-9mta0aem	176	2	on	on	IN
cord-322904-9mta0aem	176	3	SV40	SV40	NNP
cord-322904-9mta0aem	176	4	entry	entry	NN
cord-322904-9mta0aem	176	5	mechanisms	mechanism	NNS
cord-322904-9mta0aem	176	6	proceeded	proceed	VBD
cord-322904-9mta0aem	176	7	similarly	similarly	RB
cord-322904-9mta0aem	176	8	and	and	CC
cord-322904-9mta0aem	176	9	often	often	RB
cord-322904-9mta0aem	176	10	in	in	IN
cord-322904-9mta0aem	176	11	parallel	parallel	NN
cord-322904-9mta0aem	176	12	with	with	IN
cord-322904-9mta0aem	176	13	the	the	DT
cord-322904-9mta0aem	176	14	work	work	NN
cord-322904-9mta0aem	176	15	on	on	IN
cord-322904-9mta0aem	176	16	mPyV	mPyV	NNP
cord-322904-9mta0aem	176	17	described	describe	VBN
cord-322904-9mta0aem	176	18	above	above	RB
cord-322904-9mta0aem	176	19	.	.	.
cord-322904-9mta0aem	177	1	Hummeler	Hummeler	NNP
cord-322904-9mta0aem	177	2	and	and	CC
cord-322904-9mta0aem	177	3	colleagues	colleague	NNS
cord-322904-9mta0aem	177	4	followed	follow	VBD
cord-322904-9mta0aem	177	5	the	the	DT
cord-322904-9mta0aem	177	6	fate	fate	NN
cord-322904-9mta0aem	177	7	of	of	IN
cord-322904-9mta0aem	177	8	SV40	SV40	NNP
cord-322904-9mta0aem	177	9	particles	particle	NNS
cord-322904-9mta0aem	177	10	in	in	IN
cord-322904-9mta0aem	177	11	cells	cell	NNS
cord-322904-9mta0aem	177	12	by	by	IN
cord-322904-9mta0aem	177	13	electron	electron	NN
cord-322904-9mta0aem	177	14	microscopy	microscopy	NN
cord-322904-9mta0aem	178	1	(	(	-LRB-
cord-322904-9mta0aem	178	2	Hummeler	Hummeler	NNP
cord-322904-9mta0aem	178	3	et	et	NNP
cord-322904-9mta0aem	178	4	al	al	NNP
cord-322904-9mta0aem	178	5	.	.	NNP
cord-322904-9mta0aem	178	6	,	,	,
cord-322904-9mta0aem	178	7	1970	1970	CD
cord-322904-9mta0aem	178	8	)	)	-RRB-
cord-322904-9mta0aem	178	9	.	.	.
cord-322904-9mta0aem	179	1	They	-PRON-	PRP
cord-322904-9mta0aem	179	2	describe	describe	VBP
cord-322904-9mta0aem	179	3	the	the	DT
cord-322904-9mta0aem	179	4	majority	majority	NN
cord-322904-9mta0aem	179	5	of	of	IN
cord-322904-9mta0aem	179	6	particles	particle	NNS
cord-322904-9mta0aem	179	7	becoming	become	VBG
cord-322904-9mta0aem	179	8	rapidly	rapidly	RB
cord-322904-9mta0aem	179	9	enveloped	envelop	VBN
cord-322904-9mta0aem	179	10	at	at	IN
cord-322904-9mta0aem	179	11	the	the	DT
cord-322904-9mta0aem	179	12	plasma	plasma	NN
cord-322904-9mta0aem	179	13	membrane	membrane	NN
cord-322904-9mta0aem	179	14	into	into	IN
cord-322904-9mta0aem	179	15	monopinocytotic	monopinocytotic	JJ
cord-322904-9mta0aem	179	16	vesicles	vesicle	NNS
cord-322904-9mta0aem	179	17	.	.	.
cord-322904-9mta0aem	180	1	SV40	sv40	NN
cord-322904-9mta0aem	180	2	particles	particle	NNS
cord-322904-9mta0aem	180	3	could	could	MD
cord-322904-9mta0aem	180	4	be	be	VB
cord-322904-9mta0aem	180	5	seen	see	VBN
cord-322904-9mta0aem	180	6	as	as	RB
cord-322904-9mta0aem	180	7	early	early	RB
cord-322904-9mta0aem	180	8	as	as	IN
cord-322904-9mta0aem	180	9	1	1	CD
cord-322904-9mta0aem	180	10	h	h	NN
cord-322904-9mta0aem	180	11	post	post	NN
cord-322904-9mta0aem	180	12	-	-	NN
cord-322904-9mta0aem	180	13	infection	infection	NN
cord-322904-9mta0aem	180	14	in	in	IN
cord-322904-9mta0aem	180	15	the	the	DT
cord-322904-9mta0aem	180	16	nucleus	nucleus	NN
cord-322904-9mta0aem	180	17	.	.	.
cord-322904-9mta0aem	181	1	Maul	maul	VB
cord-322904-9mta0aem	181	2	and	and	CC
cord-322904-9mta0aem	181	3	colleagues	colleague	NNS
cord-322904-9mta0aem	181	4	subsequently	subsequently	RB
cord-322904-9mta0aem	181	5	investigated	investigate	VBD
cord-322904-9mta0aem	181	6	the	the	DT
cord-322904-9mta0aem	181	7	uptake	uptake	NN
cord-322904-9mta0aem	181	8	and	and	CC
cord-322904-9mta0aem	181	9	trafficking	trafficking	NN
cord-322904-9mta0aem	181	10	of	of	IN
cord-322904-9mta0aem	181	11	SV40	SV40	NNP
cord-322904-9mta0aem	181	12	in	in	IN
cord-322904-9mta0aem	181	13	permissive	permissive	JJ
cord-322904-9mta0aem	181	14	and	and	CC
cord-322904-9mta0aem	181	15	nonpermissive	nonpermissive	JJ
cord-322904-9mta0aem	181	16	cells	cell	NNS
cord-322904-9mta0aem	181	17	(	(	-LRB-
cord-322904-9mta0aem	181	18	Maul	Maul	NNP
cord-322904-9mta0aem	181	19	et	et	FW
cord-322904-9mta0aem	181	20	al	al	NNP
cord-322904-9mta0aem	181	21	.	.	NNP
cord-322904-9mta0aem	181	22	,	,	,
cord-322904-9mta0aem	181	23	1978	1978	CD
cord-322904-9mta0aem	181	24	)	)	-RRB-
cord-322904-9mta0aem	181	25	.	.	.
cord-322904-9mta0aem	182	1	No	no	DT
cord-322904-9mta0aem	182	2	qualitative	qualitative	JJ
cord-322904-9mta0aem	182	3	differences	difference	NNS
cord-322904-9mta0aem	182	4	were	be	VBD
cord-322904-9mta0aem	182	5	seen	see	VBN
cord-322904-9mta0aem	182	6	between	between	IN
cord-322904-9mta0aem	182	7	the	the	DT
cord-322904-9mta0aem	182	8	two	two	CD
cord-322904-9mta0aem	182	9	cell	cell	NN
cord-322904-9mta0aem	182	10	types	type	NNS
cord-322904-9mta0aem	182	11	indicating	indicate	VBG
cord-322904-9mta0aem	182	12	that	that	IN
cord-322904-9mta0aem	182	13	these	these	DT
cord-322904-9mta0aem	182	14	steps	step	NNS
cord-322904-9mta0aem	182	15	did	do	VBD
cord-322904-9mta0aem	182	16	not	not	RB
cord-322904-9mta0aem	182	17	restrict	restrict	VB
cord-322904-9mta0aem	182	18	virus	virus	NN
cord-322904-9mta0aem	182	19	infection	infection	NN
cord-322904-9mta0aem	182	20	of	of	IN
cord-322904-9mta0aem	182	21	cells	cell	NNS
cord-322904-9mta0aem	182	22	.	.	.
cord-322904-9mta0aem	183	1	Their	-PRON-	PRP$
cord-322904-9mta0aem	183	2	findings	finding	NNS
cord-322904-9mta0aem	183	3	were	be	VBD
cord-322904-9mta0aem	183	4	very	very	RB
cord-322904-9mta0aem	183	5	similar	similar	JJ
cord-322904-9mta0aem	183	6	to	to	IN
cord-322904-9mta0aem	183	7	those	those	DT
cord-322904-9mta0aem	183	8	of	of	IN
cord-322904-9mta0aem	183	9	Hummeler	Hummeler	NNP
cord-322904-9mta0aem	183	10	but	but	CC
cord-322904-9mta0aem	183	11	they	-PRON-	PRP
cord-322904-9mta0aem	183	12	described	describe	VBD
cord-322904-9mta0aem	183	13	several	several	JJ
cord-322904-9mta0aem	183	14	intervening	intervene	VBG
cord-322904-9mta0aem	183	15	steps	step	NNS
cord-322904-9mta0aem	183	16	in	in	IN
cord-322904-9mta0aem	183	17	the	the	DT
cord-322904-9mta0aem	183	18	entry	entry	NN
cord-322904-9mta0aem	183	19	process	process	NN
cord-322904-9mta0aem	183	20	including	include	VBG
cord-322904-9mta0aem	183	21	a	a	DT
cord-322904-9mta0aem	183	22	prominent	prominent	JJ
cord-322904-9mta0aem	183	23	association	association	NN
cord-322904-9mta0aem	183	24	of	of	IN
cord-322904-9mta0aem	183	25	viral	viral	JJ
cord-322904-9mta0aem	183	26	particles	particle	NNS
cord-322904-9mta0aem	183	27	in	in	IN
cord-322904-9mta0aem	183	28	tubular	tubular	JJ
cord-322904-9mta0aem	183	29	membrane	membrane	NN
cord-322904-9mta0aem	183	30	structures	structure	NNS
cord-322904-9mta0aem	183	31	and	and	CC
cord-322904-9mta0aem	183	32	of	of	IN
cord-322904-9mta0aem	183	33	particles	particle	NNS
cord-322904-9mta0aem	183	34	associated	associate	VBN
cord-322904-9mta0aem	183	35	with	with	IN
cord-322904-9mta0aem	183	36	rough	rough	JJ
cord-322904-9mta0aem	183	37	ER	er	NN
cord-322904-9mta0aem	183	38	.	.	.
cord-322904-9mta0aem	184	1	They	-PRON-	PRP
cord-322904-9mta0aem	184	2	did	do	VBD
cord-322904-9mta0aem	184	3	observe	observe	VB
cord-322904-9mta0aem	184	4	particles	particle	NNS
cord-322904-9mta0aem	184	5	in	in	IN
cord-322904-9mta0aem	184	6	the	the	DT
cord-322904-9mta0aem	184	7	nucleus	nucleus	NN
cord-322904-9mta0aem	184	8	but	but	CC
cord-322904-9mta0aem	184	9	these	these	DT
cord-322904-9mta0aem	184	10	particles	particle	NNS
cord-322904-9mta0aem	184	11	were	be	VBD
cord-322904-9mta0aem	184	12	not	not	RB
cord-322904-9mta0aem	184	13	surrounded	surround	VBN
cord-322904-9mta0aem	184	14	by	by	IN
cord-322904-9mta0aem	184	15	membrane	membrane	NN
cord-322904-9mta0aem	184	16	.	.	.
cord-322904-9mta0aem	185	1	They	-PRON-	PRP
cord-322904-9mta0aem	185	2	proposed	propose	VBD
cord-322904-9mta0aem	185	3	a	a	DT
cord-322904-9mta0aem	185	4	model	model	NN
cord-322904-9mta0aem	185	5	where	where	WRB
cord-322904-9mta0aem	185	6	the	the	DT
cord-322904-9mta0aem	185	7	entry	entry	NN
cord-322904-9mta0aem	185	8	of	of	IN
cord-322904-9mta0aem	185	9	SV40	SV40	NNP
cord-322904-9mta0aem	185	10	followed	follow	VBD
cord-322904-9mta0aem	185	11	a	a	DT
cord-322904-9mta0aem	185	12	series	series	NN
cord-322904-9mta0aem	185	13	of	of	IN
cord-322904-9mta0aem	185	14	membrane	membrane	NN
cord-322904-9mta0aem	185	15	fusion	fusion	NN
cord-322904-9mta0aem	185	16	and	and	CC
cord-322904-9mta0aem	185	17	fission	fission	NN
cord-322904-9mta0aem	185	18	steps	step	NNS
cord-322904-9mta0aem	185	19	eventually	eventually	RB
cord-322904-9mta0aem	185	20	liberating	liberate	VBG
cord-322904-9mta0aem	185	21	virions	virion	NNS
cord-322904-9mta0aem	185	22	in	in	IN
cord-322904-9mta0aem	185	23	the	the	DT
cord-322904-9mta0aem	185	24	nucleus	nucleus	NN
cord-322904-9mta0aem	185	25	for	for	IN
cord-322904-9mta0aem	185	26	uncoating	uncoating	NN
cord-322904-9mta0aem	185	27	.	.	.
cord-322904-9mta0aem	186	1	As	as	IN
cord-322904-9mta0aem	186	2	they	-PRON-	PRP
cord-322904-9mta0aem	186	3	observed	observe	VBD
cord-322904-9mta0aem	186	4	some	some	DT
cord-322904-9mta0aem	186	5	free	free	JJ
cord-322904-9mta0aem	186	6	virions	virion	NNS
cord-322904-9mta0aem	186	7	in	in	IN
cord-322904-9mta0aem	186	8	the	the	DT
cord-322904-9mta0aem	186	9	cytoplasm	cytoplasm	NN
cord-322904-9mta0aem	186	10	and	and	CC
cord-322904-9mta0aem	186	11	some	some	DT
cord-322904-9mta0aem	186	12	in	in	IN
cord-322904-9mta0aem	186	13	the	the	DT
cord-322904-9mta0aem	186	14	nucleus	nucleus	NN
cord-322904-9mta0aem	186	15	they	-PRON-	PRP
cord-322904-9mta0aem	186	16	proposed	propose	VBD
cord-322904-9mta0aem	186	17	that	that	IN
cord-322904-9mta0aem	186	18	the	the	DT
cord-322904-9mta0aem	186	19	nucleus	nucleus	NN
cord-322904-9mta0aem	186	20	must	must	MD
cord-322904-9mta0aem	186	21	contain	contain	VB
cord-322904-9mta0aem	186	22	an	an	DT
cord-322904-9mta0aem	186	23	uncoating	uncoate	VBG
cord-322904-9mta0aem	186	24	enzyme	enzyme	NN
cord-322904-9mta0aem	186	25	not	not	RB
cord-322904-9mta0aem	186	26	present	present	JJ
cord-322904-9mta0aem	186	27	in	in	IN
cord-322904-9mta0aem	186	28	the	the	DT
cord-322904-9mta0aem	186	29	cytosol	cytosol	NN
cord-322904-9mta0aem	186	30	.	.	.
cord-322904-9mta0aem	187	1	As	as	IN
cord-322904-9mta0aem	187	2	it	-PRON-	PRP
cord-322904-9mta0aem	187	3	turns	turn	VBZ
cord-322904-9mta0aem	187	4	out	out	RP
cord-322904-9mta0aem	187	5	it	-PRON-	PRP
cord-322904-9mta0aem	187	6	appears	appear	VBZ
cord-322904-9mta0aem	187	7	that	that	IN
cord-322904-9mta0aem	187	8	the	the	DT
cord-322904-9mta0aem	187	9	ER	ER	NNP
cord-322904-9mta0aem	187	10	contains	contain	VBZ
cord-322904-9mta0aem	187	11	the	the	DT
cord-322904-9mta0aem	187	12	necessary	necessary	JJ
cord-322904-9mta0aem	187	13	factors	factor	NNS
cord-322904-9mta0aem	187	14	for	for	IN
cord-322904-9mta0aem	187	15	uncoating	uncoating	NN
cord-322904-9mta0aem	187	16	.	.	.
cord-322904-9mta0aem	188	1	The	the	DT
cord-322904-9mta0aem	188	2	tubular	tubular	JJ
cord-322904-9mta0aem	188	3	structures	structure	NNS
cord-322904-9mta0aem	188	4	they	-PRON-	PRP
cord-322904-9mta0aem	188	5	observed	observe	VBD
cord-322904-9mta0aem	188	6	were	be	VBD
cord-322904-9mta0aem	188	7	likely	likely	JJ
cord-322904-9mta0aem	188	8	virions	virion	NNS
cord-322904-9mta0aem	188	9	pinching	pinch	VBG
cord-322904-9mta0aem	188	10	off	off	RP
cord-322904-9mta0aem	188	11	in	in	IN
cord-322904-9mta0aem	188	12	large	large	JJ
cord-322904-9mta0aem	188	13	tubular	tubular	JJ
cord-322904-9mta0aem	188	14	structures	structure	NNS
cord-322904-9mta0aem	188	15	from	from	IN
cord-322904-9mta0aem	188	16	caveosomes	caveosome	NNS
cord-322904-9mta0aem	188	17	as	as	IN
cord-322904-9mta0aem	188	18	described	describe	VBN
cord-322904-9mta0aem	188	19	by	by	IN
cord-322904-9mta0aem	188	20	Helenius	Helenius	NNP
cord-322904-9mta0aem	188	21	many	many	JJ
cord-322904-9mta0aem	188	22	years	year	NNS
cord-322904-9mta0aem	188	23	later	later	RB
cord-322904-9mta0aem	188	24	(	(	-LRB-
cord-322904-9mta0aem	188	25	Pelkmans	Pelkmans	NNPS
cord-322904-9mta0aem	188	26	et	et	NNP
cord-322904-9mta0aem	188	27	al	al	NNP
cord-322904-9mta0aem	188	28	.	.	NNP
cord-322904-9mta0aem	188	29	,	,	,
cord-322904-9mta0aem	188	30	2001	2001	CD
cord-322904-9mta0aem	188	31	)	)	-RRB-
cord-322904-9mta0aem	188	32	.	.	.
cord-322904-9mta0aem	189	1	These	these	DT
cord-322904-9mta0aem	189	2	tubular	tubular	JJ
cord-322904-9mta0aem	189	3	vesicles	vesicle	NNS
cord-322904-9mta0aem	189	4	are	be	VBP
cord-322904-9mta0aem	189	5	transported	transport	VBN
cord-322904-9mta0aem	189	6	to	to	IN
cord-322904-9mta0aem	189	7	the	the	DT
cord-322904-9mta0aem	189	8	ER	ER	NNP
cord-322904-9mta0aem	189	9	in	in	IN
cord-322904-9mta0aem	189	10	a	a	DT
cord-322904-9mta0aem	189	11	microtubual	microtubual	JJ
cord-322904-9mta0aem	189	12	dependent	dependent	JJ
cord-322904-9mta0aem	189	13	manner	manner	NN
cord-322904-9mta0aem	190	1	(	(	-LRB-
cord-322904-9mta0aem	190	2	Pelkmans	Pelkmans	NNP
cord-322904-9mta0aem	190	3	et	et	NNP
cord-322904-9mta0aem	190	4	al	al	NNP
cord-322904-9mta0aem	190	5	.	.	NNP
cord-322904-9mta0aem	190	6	,	,	,
cord-322904-9mta0aem	190	7	2001	2001	CD
cord-322904-9mta0aem	190	8	)	)	-RRB-
cord-322904-9mta0aem	191	1	(	(	-LRB-
cord-322904-9mta0aem	191	2	Fig	Fig	NNP
cord-322904-9mta0aem	191	3	.	.	NNP
cord-322904-9mta0aem	191	4	2	2	CD
cord-322904-9mta0aem	191	5	)	)	-RRB-
cord-322904-9mta0aem	191	6	.	.	.
cord-322904-9mta0aem	192	1	We	-PRON-	PRP
cord-322904-9mta0aem	192	2	now	now	RB
cord-322904-9mta0aem	192	3	appreciate	appreciate	VBP
cord-322904-9mta0aem	192	4	that	that	IN
cord-322904-9mta0aem	192	5	most	most	JJS
cord-322904-9mta0aem	192	6	if	if	IN
cord-322904-9mta0aem	192	7	not	not	RB
cord-322904-9mta0aem	192	8	all	all	DT
cord-322904-9mta0aem	192	9	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	192	10	are	be	VBP
cord-322904-9mta0aem	192	11	trafficked	traffic	VBN
cord-322904-9mta0aem	192	12	to	to	IN
cord-322904-9mta0aem	192	13	the	the	DT
cord-322904-9mta0aem	192	14	ER	ER	NNP
cord-322904-9mta0aem	192	15	where	where	WRB
cord-322904-9mta0aem	192	16	uncoating	uncoating	NN
cord-322904-9mta0aem	192	17	occurs	occur	VBZ
cord-322904-9mta0aem	192	18	or	or	CC
cord-322904-9mta0aem	192	19	at	at	IN
cord-322904-9mta0aem	192	20	least	least	JJS
cord-322904-9mta0aem	192	21	begins	begin	VBZ
cord-322904-9mta0aem	192	22	.	.	.
cord-322904-9mta0aem	193	1	The	the	DT
cord-322904-9mta0aem	193	2	single	single	JJ
cord-322904-9mta0aem	193	3	virus	virus	NN
cord-322904-9mta0aem	193	4	particles	particle	NNS
cord-322904-9mta0aem	193	5	being	be	VBG
cord-322904-9mta0aem	193	6	enclosed	enclose	VBN
cord-322904-9mta0aem	193	7	in	in	IN
cord-322904-9mta0aem	193	8	membranous	membranous	JJ
cord-322904-9mta0aem	193	9	vesicles	vesicle	NNS
cord-322904-9mta0aem	193	10	at	at	IN
cord-322904-9mta0aem	193	11	the	the	DT
cord-322904-9mta0aem	193	12	plasma	plasma	NN
cord-322904-9mta0aem	193	13	membrane	membrane	NN
cord-322904-9mta0aem	193	14	described	describe	VBN
cord-322904-9mta0aem	193	15	in	in	IN
cord-322904-9mta0aem	193	16	the	the	DT
cord-322904-9mta0aem	193	17	Maul	Maul	NNP
cord-322904-9mta0aem	193	18	paper	paper	NN
cord-322904-9mta0aem	193	19	were	be	VBD
cord-322904-9mta0aem	193	20	the	the	DT
cord-322904-9mta0aem	193	21	first	first	JJ
cord-322904-9mta0aem	193	22	demonstration	demonstration	NN
cord-322904-9mta0aem	193	23	of	of	IN
cord-322904-9mta0aem	193	24	caveolae	caveolae	NNP
cord-322904-9mta0aem	193	25	which	which	WDT
cord-322904-9mta0aem	193	26	were	be	VBD
cord-322904-9mta0aem	193	27	only	only	RB
cord-322904-9mta0aem	193	28	later	later	RB
cord-322904-9mta0aem	193	29	appreciated	appreciate	VBN
cord-322904-9mta0aem	193	30	as	as	IN
cord-322904-9mta0aem	193	31	being	be	VBG
cord-322904-9mta0aem	193	32	critical	critical	JJ
cord-322904-9mta0aem	193	33	organelles	organelle	NNS
cord-322904-9mta0aem	193	34	for	for	IN
cord-322904-9mta0aem	193	35	SV40	SV40	NNP
cord-322904-9mta0aem	193	36	entry	entry	NN
cord-322904-9mta0aem	193	37	into	into	IN
cord-322904-9mta0aem	193	38	cells	cell	NNS
cord-322904-9mta0aem	193	39	(	(	-LRB-
cord-322904-9mta0aem	193	40	Anderson	Anderson	NNP
cord-322904-9mta0aem	193	41	et	et	NNP
cord-322904-9mta0aem	193	42	al	al	NNP
cord-322904-9mta0aem	193	43	.	.	NNP
cord-322904-9mta0aem	193	44	,	,	,
cord-322904-9mta0aem	193	45	1996	1996	CD
cord-322904-9mta0aem	193	46	)	)	-RRB-
cord-322904-9mta0aem	194	1	(	(	-LRB-
cord-322904-9mta0aem	194	2	Fig	Fig	NNP
cord-322904-9mta0aem	194	3	.	.	NNP
cord-322904-9mta0aem	194	4	2	2	CD
cord-322904-9mta0aem	194	5	)	)	-RRB-
cord-322904-9mta0aem	194	6	.	.	.
cord-322904-9mta0aem	195	1	Caveolae	Caveolae	NNP
cord-322904-9mta0aem	195	2	are	be	VBP
cord-322904-9mta0aem	195	3	membrane	membrane	NN
cord-322904-9mta0aem	195	4	microdomains	microdomain	NNS
cord-322904-9mta0aem	195	5	rich	rich	JJ
cord-322904-9mta0aem	195	6	in	in	IN
cord-322904-9mta0aem	195	7	sphingolipids	sphingolipid	NNS
cord-322904-9mta0aem	195	8	and	and	CC
cord-322904-9mta0aem	195	9	signaling	signal	VBG
cord-322904-9mta0aem	195	10	molecules	molecule	NNS
cord-322904-9mta0aem	195	11	.	.	.
cord-322904-9mta0aem	196	1	SV40	SV40	NNP
cord-322904-9mta0aem	196	2	exploits	exploit	VBZ
cord-322904-9mta0aem	196	3	these	these	DT
cord-322904-9mta0aem	196	4	domains	domain	NNS
cord-322904-9mta0aem	196	5	most	most	RBS
cord-322904-9mta0aem	196	6	likely	likely	JJ
cord-322904-9mta0aem	196	7	by	by	IN
cord-322904-9mta0aem	196	8	virtue	virtue	NN
cord-322904-9mta0aem	196	9	of	of	IN
cord-322904-9mta0aem	196	10	its	-PRON-	PRP$
cord-322904-9mta0aem	196	11	interaction	interaction	NN
cord-322904-9mta0aem	196	12	with	with	IN
cord-322904-9mta0aem	196	13	the	the	DT
cord-322904-9mta0aem	196	14	ganglioside	ganglioside	NN
cord-322904-9mta0aem	196	15	GM1	GM1	NNP
cord-322904-9mta0aem	196	16	.	.	.
cord-322904-9mta0aem	197	1	Entry	entry	NN
cord-322904-9mta0aem	197	2	is	be	VBZ
cord-322904-9mta0aem	197	3	relatively	relatively	RB
cord-322904-9mta0aem	197	4	slow	slow	JJ
cord-322904-9mta0aem	197	5	and	and	CC
cord-322904-9mta0aem	197	6	proceeds	proceed	VBZ
cord-322904-9mta0aem	197	7	in	in	IN
cord-322904-9mta0aem	197	8	a	a	DT
cord-322904-9mta0aem	197	9	pH	pH	NNP
cord-322904-9mta0aem	197	10	neutral	neutral	JJ
cord-322904-9mta0aem	197	11	manner	manner	NN
cord-322904-9mta0aem	197	12	from	from	IN
cord-322904-9mta0aem	197	13	caveolae	caveolae	NNP
cord-322904-9mta0aem	197	14	to	to	IN
cord-322904-9mta0aem	197	15	caveosomes	caveosome	NNS
cord-322904-9mta0aem	197	16	to	to	IN
cord-322904-9mta0aem	197	17	the	the	DT
cord-322904-9mta0aem	197	18	ER	er	NN
cord-322904-9mta0aem	198	1	(	(	-LRB-
cord-322904-9mta0aem	198	2	Pelkmans	Pelkmans	NNP
cord-322904-9mta0aem	198	3	et	et	NNP
cord-322904-9mta0aem	198	4	al	al	NNP
cord-322904-9mta0aem	198	5	.	.	NNP
cord-322904-9mta0aem	198	6	,	,	,
cord-322904-9mta0aem	198	7	2001	2001	CD
cord-322904-9mta0aem	198	8	)	)	-RRB-
cord-322904-9mta0aem	198	9	.	.	.
cord-322904-9mta0aem	199	1	In	in	IN
cord-322904-9mta0aem	199	2	addition	addition	NN
cord-322904-9mta0aem	199	3	to	to	IN
cord-322904-9mta0aem	199	4	the	the	DT
cord-322904-9mta0aem	199	5	ganglioside	ganglioside	NN
cord-322904-9mta0aem	199	6	GM1	GM1	NNP
cord-322904-9mta0aem	199	7	,	,	,
cord-322904-9mta0aem	199	8	SV40	SV40	NNP
cord-322904-9mta0aem	199	9	was	be	VBD
cord-322904-9mta0aem	199	10	also	also	RB
cord-322904-9mta0aem	199	11	reported	report	VBN
cord-322904-9mta0aem	199	12	to	to	TO
cord-322904-9mta0aem	199	13	use	use	VB
cord-322904-9mta0aem	199	14	MHC	MHC	NNP
cord-322904-9mta0aem	199	15	class	class	NN
cord-322904-9mta0aem	199	16	I	-PRON-	PRP
cord-322904-9mta0aem	199	17	molecules	molecule	VBZ
cord-322904-9mta0aem	199	18	to	to	TO
cord-322904-9mta0aem	199	19	infect	infect	VB
cord-322904-9mta0aem	199	20	permissive	permissive	JJ
cord-322904-9mta0aem	199	21	cells	cell	NNS
cord-322904-9mta0aem	199	22	(	(	-LRB-
cord-322904-9mta0aem	199	23	Atwood	Atwood	NNP
cord-322904-9mta0aem	199	24	and	and	CC
cord-322904-9mta0aem	199	25	Norkin	Norkin	NNP
cord-322904-9mta0aem	199	26	,	,	,
cord-322904-9mta0aem	199	27	1989	1989	CD
cord-322904-9mta0aem	199	28	)	)	-RRB-
cord-322904-9mta0aem	200	1	(	(	-LRB-
cord-322904-9mta0aem	200	2	Table	table	NN
cord-322904-9mta0aem	200	3	 	 	_SP
cord-322904-9mta0aem	200	4	1	1	CD
cord-322904-9mta0aem	200	5	)	)	-RRB-
cord-322904-9mta0aem	200	6	.	.	.
cord-322904-9mta0aem	201	1	The	the	DT
cord-322904-9mta0aem	201	2	virus	virus	NN
cord-322904-9mta0aem	201	3	can	can	MD
cord-322904-9mta0aem	201	4	infect	infect	VB
cord-322904-9mta0aem	201	5	some	some	DT
cord-322904-9mta0aem	201	6	cells	cell	NNS
cord-322904-9mta0aem	201	7	lacking	lack	VBG
cord-322904-9mta0aem	201	8	MHC	MHC	NNP
cord-322904-9mta0aem	201	9	I	I	NNP
cord-322904-9mta0aem	201	10	and	and	CC
cord-322904-9mta0aem	201	11	in	in	IN
cord-322904-9mta0aem	201	12	these	these	DT
cord-322904-9mta0aem	201	13	cases	case	NNS
cord-322904-9mta0aem	201	14	GM1	GM1	NNP
cord-322904-9mta0aem	201	15	is	be	VBZ
cord-322904-9mta0aem	201	16	the	the	DT
cord-322904-9mta0aem	201	17	principle	principle	JJ
cord-322904-9mta0aem	201	18	receptor	receptor	NN
cord-322904-9mta0aem	201	19	although	although	IN
cord-322904-9mta0aem	201	20	infection	infection	NN
cord-322904-9mta0aem	201	21	is	be	VBZ
cord-322904-9mta0aem	201	22	inefficient	inefficient	JJ
cord-322904-9mta0aem	201	23	.	.	.
cord-322904-9mta0aem	202	1	The	the	DT
cord-322904-9mta0aem	202	2	relationship	relationship	NN
cord-322904-9mta0aem	202	3	between	between	IN
cord-322904-9mta0aem	202	4	these	these	DT
cord-322904-9mta0aem	202	5	receptors	receptor	NNS
cord-322904-9mta0aem	202	6	remains	remain	VBZ
cord-322904-9mta0aem	202	7	unclear	unclear	JJ
cord-322904-9mta0aem	202	8	.	.	.
cord-322904-9mta0aem	203	1	The	the	DT
cord-322904-9mta0aem	203	2	human	human	JJ
cord-322904-9mta0aem	203	3	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	203	4	,	,	,
cord-322904-9mta0aem	203	5	JCV	JCV	NNP
cord-322904-9mta0aem	203	6	and	and	CC
cord-322904-9mta0aem	203	7	BKV	BKV	NNP
cord-322904-9mta0aem	203	8	were	be	VBD
cord-322904-9mta0aem	203	9	discovered	discover	VBN
cord-322904-9mta0aem	203	10	more	more	RBR
cord-322904-9mta0aem	203	11	recently	recently	RB
cord-322904-9mta0aem	203	12	and	and	CC
cord-322904-9mta0aem	203	13	difficulties	difficulty	NNS
cord-322904-9mta0aem	203	14	in	in	IN
cord-322904-9mta0aem	203	15	isolating	isolate	VBG
cord-322904-9mta0aem	203	16	receptors	receptor	NNS
cord-322904-9mta0aem	203	17	for	for	IN
cord-322904-9mta0aem	203	18	the	the	DT
cord-322904-9mta0aem	203	19	mouse	mouse	NN
cord-322904-9mta0aem	203	20	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	203	21	and	and	CC
cord-322904-9mta0aem	203	22	SV40	SV40	NNP
cord-322904-9mta0aem	203	23	probably	probably	RB
cord-322904-9mta0aem	203	24	precluded	preclude	VBD
cord-322904-9mta0aem	203	25	any	any	DT
cord-322904-9mta0aem	203	26	interest	interest	NN
cord-322904-9mta0aem	203	27	in	in	IN
cord-322904-9mta0aem	203	28	pursuing	pursue	VBG
cord-322904-9mta0aem	203	29	this	this	DT
cord-322904-9mta0aem	203	30	with	with	IN
cord-322904-9mta0aem	203	31	JCV	JCV	NNP
cord-322904-9mta0aem	203	32	and	and	CC
cord-322904-9mta0aem	203	33	BKV	BKV	NNP
cord-322904-9mta0aem	203	34	as	as	IN
cord-322904-9mta0aem	203	35	both	both	DT
cord-322904-9mta0aem	203	36	are	be	VBP
cord-322904-9mta0aem	203	37	somewhat	somewhat	RB
cord-322904-9mta0aem	203	38	more	more	RBR
cord-322904-9mta0aem	203	39	difficult	difficult	JJ
cord-322904-9mta0aem	203	40	to	to	TO
cord-322904-9mta0aem	203	41	propagate	propagate	VB
cord-322904-9mta0aem	203	42	than	than	IN
cord-322904-9mta0aem	203	43	SV40	SV40	NNP
cord-322904-9mta0aem	203	44	or	or	CC
cord-322904-9mta0aem	203	45	the	the	DT
cord-322904-9mta0aem	203	46	mouse	mouse	NN
cord-322904-9mta0aem	203	47	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	203	48	.	.	.
cord-322904-9mta0aem	204	1	With	with	IN
cord-322904-9mta0aem	204	2	the	the	DT
cord-322904-9mta0aem	204	3	introduction	introduction	NN
cord-322904-9mta0aem	204	4	of	of	IN
cord-322904-9mta0aem	204	5	new	new	JJ
cord-322904-9mta0aem	204	6	tools	tool	NNS
cord-322904-9mta0aem	204	7	and	and	CC
cord-322904-9mta0aem	204	8	techniques	technique	NNS
cord-322904-9mta0aem	204	9	these	these	DT
cord-322904-9mta0aem	204	10	issues	issue	NNS
cord-322904-9mta0aem	204	11	have	have	VBP
cord-322904-9mta0aem	204	12	begun	begin	VBN
cord-322904-9mta0aem	204	13	to	to	TO
cord-322904-9mta0aem	204	14	be	be	VB
cord-322904-9mta0aem	204	15	explored	explore	VBN
cord-322904-9mta0aem	204	16	by	by	IN
cord-322904-9mta0aem	204	17	several	several	JJ
cord-322904-9mta0aem	204	18	groups	group	NNS
cord-322904-9mta0aem	204	19	.	.	.
cord-322904-9mta0aem	205	1	Both	both	DT
cord-322904-9mta0aem	205	2	of	of	IN
cord-322904-9mta0aem	205	3	the	the	DT
cord-322904-9mta0aem	205	4	human	human	JJ
cord-322904-9mta0aem	205	5	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	205	6	require	require	VBP
cord-322904-9mta0aem	205	7	sialic	sialic	JJ
cord-322904-9mta0aem	205	8	acid	acid	NN
cord-322904-9mta0aem	205	9	to	to	TO
cord-322904-9mta0aem	205	10	infect	infect	VB
cord-322904-9mta0aem	205	11	cells	cell	NNS
cord-322904-9mta0aem	205	12	.	.	.
cord-322904-9mta0aem	206	1	JCV	JCV	NNP
cord-322904-9mta0aem	206	2	can	can	MD
cord-322904-9mta0aem	206	3	use	use	VB
cord-322904-9mta0aem	206	4	either	either	CC
cord-322904-9mta0aem	206	5	an	an	DT
cord-322904-9mta0aem	206	6	α2,3or	α2,3or	NNP
cord-322904-9mta0aem	206	7	an	an	DT
cord-322904-9mta0aem	206	8	α2,6-linked	α2,6-linked	CD
cord-322904-9mta0aem	206	9	sialic	sialic	NN
cord-322904-9mta0aem	206	10	acid	acid	NN
cord-322904-9mta0aem	206	11	to	to	TO
cord-322904-9mta0aem	206	12	infect	infect	VB
cord-322904-9mta0aem	206	13	permissive	permissive	JJ
cord-322904-9mta0aem	206	14	glial	glial	JJ
cord-322904-9mta0aem	206	15	cells	cell	NNS
cord-322904-9mta0aem	206	16	(	(	-LRB-
cord-322904-9mta0aem	206	17	Dugan	Dugan	NNP
cord-322904-9mta0aem	206	18	et	et	NNP
cord-322904-9mta0aem	206	19	al	al	NNP
cord-322904-9mta0aem	206	20	.	.	NNP
cord-322904-9mta0aem	206	21	,	,	,
cord-322904-9mta0aem	206	22	2007	2007	CD
cord-322904-9mta0aem	206	23	;	;	:
cord-322904-9mta0aem	206	24	Liu	Liu	NNP
cord-322904-9mta0aem	206	25	et	et	NNP
cord-322904-9mta0aem	206	26	al	al	NNP
cord-322904-9mta0aem	206	27	.	.	NNP
cord-322904-9mta0aem	206	28	,	,	,
cord-322904-9mta0aem	206	29	1998	1998	CD
cord-322904-9mta0aem	206	30	)	)	-RRB-
cord-322904-9mta0aem	206	31	and	and	CC
cord-322904-9mta0aem	206	32	a	a	DT
cord-322904-9mta0aem	206	33	ganglioside	ganglioside	NN
cord-322904-9mta0aem	206	34	(	(	-LRB-
cord-322904-9mta0aem	206	35	GT1b	GT1b	NNP
cord-322904-9mta0aem	206	36	)	)	-RRB-
cord-322904-9mta0aem	206	37	may	may	MD
cord-322904-9mta0aem	206	38	also	also	RB
cord-322904-9mta0aem	206	39	be	be	VB
cord-322904-9mta0aem	206	40	involved	involve	VBN
cord-322904-9mta0aem	206	41	(	(	-LRB-
cord-322904-9mta0aem	207	1	Komagome	Komagome	NNP
cord-322904-9mta0aem	207	2	et	et	NNP
cord-322904-9mta0aem	207	3	al	al	NNP
cord-322904-9mta0aem	207	4	.	.	.
cord-322904-9mta0aem	208	1	,	,	,
cord-322904-9mta0aem	208	2	2002	2002	CD
cord-322904-9mta0aem	208	3	)	)	-RRB-
cord-322904-9mta0aem	208	4	(	(	-LRB-
cord-322904-9mta0aem	208	5	Table	table	NN
cord-322904-9mta0aem	208	6	1	1	CD
cord-322904-9mta0aem	208	7	)	)	-RRB-
cord-322904-9mta0aem	208	8	.	.	.
cord-322904-9mta0aem	209	1	BKV	BKV	NNP
cord-322904-9mta0aem	209	2	uses	use	VBZ
cord-322904-9mta0aem	209	3	only	only	RB
cord-322904-9mta0aem	209	4	the	the	DT
cord-322904-9mta0aem	209	5	α2,3-linkage	α2,3-linkage	TO
cord-322904-9mta0aem	209	6	to	to	TO
cord-322904-9mta0aem	209	7	infect	infect	VB
cord-322904-9mta0aem	209	8	cells	cell	NNS
cord-322904-9mta0aem	209	9	(	(	-LRB-
cord-322904-9mta0aem	209	10	Dugan	Dugan	NNP
cord-322904-9mta0aem	209	11	et	et	NNP
cord-322904-9mta0aem	209	12	al	al	NNP
cord-322904-9mta0aem	209	13	.	.	NNP
cord-322904-9mta0aem	209	14	,	,	,
cord-322904-9mta0aem	209	15	2005	2005	CD
cord-322904-9mta0aem	209	16	)	)	-RRB-
cord-322904-9mta0aem	210	1	(	(	-LRB-
cord-322904-9mta0aem	210	2	Table	table	NN
cord-322904-9mta0aem	210	3	1	1	CD
cord-322904-9mta0aem	210	4	)	)	-RRB-
cord-322904-9mta0aem	210	5	.	.	.
cord-322904-9mta0aem	211	1	A	a	DT
cord-322904-9mta0aem	211	2	prominent	prominent	JJ
cord-322904-9mta0aem	211	3	role	role	NN
cord-322904-9mta0aem	211	4	for	for	IN
cord-322904-9mta0aem	211	5	the	the	DT
cord-322904-9mta0aem	211	6	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	211	7	GD1b	GD1b	NNP
cord-322904-9mta0aem	211	8	and	and	CC
cord-322904-9mta0aem	211	9	GT1b	GT1b	NNP
cord-322904-9mta0aem	211	10	has	have	VBZ
cord-322904-9mta0aem	211	11	been	be	VBN
cord-322904-9mta0aem	211	12	observed	observe	VBN
cord-322904-9mta0aem	211	13	for	for	IN
cord-322904-9mta0aem	211	14	BKV	BKV	NNP
cord-322904-9mta0aem	211	15	infection	infection	NN
cord-322904-9mta0aem	211	16	of	of	IN
cord-322904-9mta0aem	211	17	kidney	kidney	NN
cord-322904-9mta0aem	211	18	cells	cell	NNS
cord-322904-9mta0aem	211	19	(	(	-LRB-
cord-322904-9mta0aem	212	1	Low	low	JJ
cord-322904-9mta0aem	212	2	et	et	FW
cord-322904-9mta0aem	212	3	al	al	NNP
cord-322904-9mta0aem	212	4	.	.	.
cord-322904-9mta0aem	213	1	,	,	,
cord-322904-9mta0aem	213	2	2006	2006	CD
cord-322904-9mta0aem	213	3	)	)	-RRB-
cord-322904-9mta0aem	213	4	(	(	-LRB-
cord-322904-9mta0aem	213	5	Table	table	NN
cord-322904-9mta0aem	213	6	1	1	CD
cord-322904-9mta0aem	213	7	)	)	-RRB-
cord-322904-9mta0aem	213	8	.	.	.
cord-322904-9mta0aem	214	1	BKV	bkv	NN
cord-322904-9mta0aem	214	2	entry	entry	NN
cord-322904-9mta0aem	214	3	into	into	IN
cord-322904-9mta0aem	214	4	cells	cell	NNS
cord-322904-9mta0aem	214	5	is	be	VBZ
cord-322904-9mta0aem	214	6	also	also	RB
cord-322904-9mta0aem	214	7	similar	similar	JJ
cord-322904-9mta0aem	214	8	to	to	IN
cord-322904-9mta0aem	214	9	that	that	DT
cord-322904-9mta0aem	214	10	of	of	IN
cord-322904-9mta0aem	214	11	SV40	SV40	NNP
cord-322904-9mta0aem	214	12	,	,	,
cord-322904-9mta0aem	214	13	using	use	VBG
cord-322904-9mta0aem	214	14	caveolae	caveolae	NNP
cord-322904-9mta0aem	214	15	mediated	mediate	VBD
cord-322904-9mta0aem	214	16	endocytosis	endocytosis	NN
cord-322904-9mta0aem	214	17	to	to	TO
cord-322904-9mta0aem	214	18	presumably	presumably	RB
cord-322904-9mta0aem	214	19	deliver	deliver	VB
cord-322904-9mta0aem	214	20	the	the	DT
cord-322904-9mta0aem	214	21	virus	virus	NN
cord-322904-9mta0aem	214	22	to	to	IN
cord-322904-9mta0aem	214	23	the	the	DT
cord-322904-9mta0aem	214	24	ER	ER	NNP
cord-322904-9mta0aem	214	25	for	for	IN
cord-322904-9mta0aem	214	26	uncoating	uncoate	VBG
cord-322904-9mta0aem	214	27	(	(	-LRB-
cord-322904-9mta0aem	214	28	Fig	Fig	NNP
cord-322904-9mta0aem	214	29	.	.	NNP
cord-322904-9mta0aem	214	30	2	2	CD
cord-322904-9mta0aem	214	31	)	)	-RRB-
cord-322904-9mta0aem	214	32	.	.	.
cord-322904-9mta0aem	215	1	JCV	JCV	NNP
cord-322904-9mta0aem	215	2	behaves	behave	VBZ
cord-322904-9mta0aem	215	3	differently	differently	RB
cord-322904-9mta0aem	215	4	than	than	IN
cord-322904-9mta0aem	215	5	any	any	DT
cord-322904-9mta0aem	215	6	of	of	IN
cord-322904-9mta0aem	215	7	the	the	DT
cord-322904-9mta0aem	215	8	described	describe	VBN
cord-322904-9mta0aem	215	9	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	215	10	and	and	CC
cord-322904-9mta0aem	215	11	rather	rather	RB
cord-322904-9mta0aem	215	12	than	than	IN
cord-322904-9mta0aem	215	13	being	be	VBG
cord-322904-9mta0aem	215	14	internalized	internalize	VBN
cord-322904-9mta0aem	215	15	directly	directly	RB
cord-322904-9mta0aem	215	16	into	into	IN
cord-322904-9mta0aem	215	17	caveolae	caveolae	NNP
cord-322904-9mta0aem	215	18	the	the	DT
cord-322904-9mta0aem	215	19	virus	virus	NN
cord-322904-9mta0aem	215	20	utilizes	utilize	VBZ
cord-322904-9mta0aem	215	21	clathrin	clathrin	NN
cord-322904-9mta0aem	215	22	dependent	dependent	JJ
cord-322904-9mta0aem	215	23	mechanisms	mechanism	NNS
cord-322904-9mta0aem	215	24	to	to	TO
cord-322904-9mta0aem	215	25	infect	infect	VB
cord-322904-9mta0aem	215	26	the	the	DT
cord-322904-9mta0aem	215	27	cell	cell	NN
cord-322904-9mta0aem	215	28	(	(	-LRB-
cord-322904-9mta0aem	215	29	Pho	Pho	NNP
cord-322904-9mta0aem	215	30	et	et	FW
cord-322904-9mta0aem	215	31	al	al	NNP
cord-322904-9mta0aem	215	32	.	.	NNP
cord-322904-9mta0aem	215	33	,	,	,
cord-322904-9mta0aem	215	34	2000	2000	CD
cord-322904-9mta0aem	215	35	)	)	-RRB-
cord-322904-9mta0aem	216	1	(	(	-LRB-
cord-322904-9mta0aem	216	2	Fig	Fig	NNP
cord-322904-9mta0aem	216	3	.	.	NNP
cord-322904-9mta0aem	216	4	2	2	CD
cord-322904-9mta0aem	216	5	)	)	-RRB-
cord-322904-9mta0aem	216	6	.	.	.
cord-322904-9mta0aem	217	1	Virus	virus	NN
cord-322904-9mta0aem	217	2	entry	entry	NN
cord-322904-9mta0aem	217	3	proceeds	proceed	NNS
cord-322904-9mta0aem	217	4	by	by	IN
cord-322904-9mta0aem	217	5	the	the	DT
cord-322904-9mta0aem	217	6	normal	normal	JJ
cord-322904-9mta0aem	217	7	clathrin	clathrin	NN
cord-322904-9mta0aem	217	8	dependent	dependent	JJ
cord-322904-9mta0aem	217	9	pathway	pathway	NN
cord-322904-9mta0aem	217	10	to	to	IN
cord-322904-9mta0aem	217	11	early	early	JJ
cord-322904-9mta0aem	217	12	endosomes	endosome	NNS
cord-322904-9mta0aem	217	13	(	(	-LRB-
cord-322904-9mta0aem	217	14	Fig	fig	NN
cord-322904-9mta0aem	217	15	.	.	NNP
cord-322904-9mta0aem	217	16	2	2	CD
cord-322904-9mta0aem	217	17	)	)	-RRB-
cord-322904-9mta0aem	217	18	.	.	.
cord-322904-9mta0aem	218	1	Once	once	RB
cord-322904-9mta0aem	218	2	in	in	IN
cord-322904-9mta0aem	218	3	the	the	DT
cord-322904-9mta0aem	218	4	early	early	JJ
cord-322904-9mta0aem	218	5	endosome	endosome	NN
cord-322904-9mta0aem	218	6	,	,	,
cord-322904-9mta0aem	218	7	however	however	RB
cord-322904-9mta0aem	218	8	,	,	,
cord-322904-9mta0aem	218	9	the	the	DT
cord-322904-9mta0aem	218	10	virus	virus	NN
cord-322904-9mta0aem	218	11	is	be	VBZ
cord-322904-9mta0aem	218	12	transported	transport	VBN
cord-322904-9mta0aem	218	13	to	to	IN
cord-322904-9mta0aem	218	14	caveosomes	caveosome	NNS
cord-322904-9mta0aem	218	15	in	in	IN
cord-322904-9mta0aem	218	16	a	a	DT
cord-322904-9mta0aem	218	17	pH	pH	NNP
cord-322904-9mta0aem	218	18	dependent	dependent	JJ
cord-322904-9mta0aem	218	19	manner	manner	NN
cord-322904-9mta0aem	218	20	(	(	-LRB-
cord-322904-9mta0aem	218	21	Querbes	Querbes	NNP
cord-322904-9mta0aem	218	22	et	et	NNP
cord-322904-9mta0aem	218	23	al	al	NNP
cord-322904-9mta0aem	218	24	.	.	NNP
cord-322904-9mta0aem	218	25	,	,	,
cord-322904-9mta0aem	218	26	2006	2006	CD
cord-322904-9mta0aem	218	27	)	)	-RRB-
cord-322904-9mta0aem	218	28	.	.	.
cord-322904-9mta0aem	219	1	From	from	IN
cord-322904-9mta0aem	219	2	here	here	RB
cord-322904-9mta0aem	219	3	the	the	DT
cord-322904-9mta0aem	219	4	virus	virus	NN
cord-322904-9mta0aem	219	5	is	be	VBZ
cord-322904-9mta0aem	219	6	most	most	RBS
cord-322904-9mta0aem	219	7	likely	likely	RB
cord-322904-9mta0aem	219	8	transported	transport	VBN
cord-322904-9mta0aem	219	9	to	to	IN
cord-322904-9mta0aem	219	10	the	the	DT
cord-322904-9mta0aem	219	11	ER	ER	NNP
cord-322904-9mta0aem	219	12	,	,	,
cord-322904-9mta0aem	219	13	presumably	presumably	RB
cord-322904-9mta0aem	219	14	the	the	DT
cord-322904-9mta0aem	219	15	common	common	JJ
cord-322904-9mta0aem	219	16	site	site	NN
cord-322904-9mta0aem	219	17	of	of	IN
cord-322904-9mta0aem	219	18	all	all	DT
cord-322904-9mta0aem	219	19	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	219	20	uncoating	uncoate	VBG
cord-322904-9mta0aem	219	21	events	event	NNS
cord-322904-9mta0aem	219	22	in	in	IN
cord-322904-9mta0aem	219	23	the	the	DT
cord-322904-9mta0aem	219	24	cell	cell	NN
cord-322904-9mta0aem	219	25	.	.	.
cord-322904-9mta0aem	220	1	In	in	IN
cord-322904-9mta0aem	220	2	addition	addition	NN
cord-322904-9mta0aem	220	3	to	to	IN
cord-322904-9mta0aem	220	4	utilizing	utilize	VBG
cord-322904-9mta0aem	220	5	sialic	sialic	JJ
cord-322904-9mta0aem	220	6	acid	acid	NN
cord-322904-9mta0aem	220	7	as	as	IN
cord-322904-9mta0aem	220	8	a	a	DT
cord-322904-9mta0aem	220	9	receptor	receptor	NN
cord-322904-9mta0aem	220	10	JCV	JCV	NNP
cord-322904-9mta0aem	220	11	has	have	VBZ
cord-322904-9mta0aem	220	12	been	be	VBN
cord-322904-9mta0aem	220	13	shown	show	VBN
cord-322904-9mta0aem	220	14	to	to	TO
cord-322904-9mta0aem	220	15	require	require	VB
cord-322904-9mta0aem	220	16	the	the	DT
cord-322904-9mta0aem	220	17	serotonin	serotonin	NN
cord-322904-9mta0aem	220	18	receptor	receptor	NN
cord-322904-9mta0aem	220	19	,	,	,
cord-322904-9mta0aem	220	20	5HT2aR	5ht2ar	CD
cord-322904-9mta0aem	220	21	,	,	,
cord-322904-9mta0aem	220	22	to	to	TO
cord-322904-9mta0aem	220	23	infect	infect	VB
cord-322904-9mta0aem	220	24	glial	glial	JJ
cord-322904-9mta0aem	220	25	cells	cell	NNS
cord-322904-9mta0aem	220	26	(	(	-LRB-
cord-322904-9mta0aem	220	27	Fonseca	Fonseca	NNP
cord-322904-9mta0aem	220	28	-	-	HYPH
cord-322904-9mta0aem	220	29	Elphick	Elphick	NNP
cord-322904-9mta0aem	220	30	et	et	NNP
cord-322904-9mta0aem	220	31	al	al	NNP
cord-322904-9mta0aem	220	32	.	.	NNP
cord-322904-9mta0aem	220	33	,	,	,
cord-322904-9mta0aem	220	34	2004	2004	CD
cord-322904-9mta0aem	220	35	)	)	-RRB-
cord-322904-9mta0aem	220	36	(	(	-LRB-
cord-322904-9mta0aem	220	37	Table	table	NN
cord-322904-9mta0aem	220	38	1	1	CD
cord-322904-9mta0aem	220	39	)	)	-RRB-
cord-322904-9mta0aem	220	40	.	.	.
cord-322904-9mta0aem	221	1	The	the	DT
cord-322904-9mta0aem	221	2	5HT2a	5ht2a	CD
cord-322904-9mta0aem	221	3	receptor	receptor	NN
cord-322904-9mta0aem	221	4	is	be	VBZ
cord-322904-9mta0aem	221	5	sufficient	sufficient	JJ
cord-322904-9mta0aem	221	6	to	to	TO
cord-322904-9mta0aem	221	7	confer	confer	VB
cord-322904-9mta0aem	221	8	susceptibility	susceptibility	NN
cord-322904-9mta0aem	221	9	to	to	IN
cord-322904-9mta0aem	221	10	cells	cell	NNS
cord-322904-9mta0aem	221	11	lacking	lack	VBG
cord-322904-9mta0aem	221	12	this	this	DT
cord-322904-9mta0aem	221	13	receptor	receptor	NN
cord-322904-9mta0aem	221	14	(	(	-LRB-
cord-322904-9mta0aem	221	15	HeLa	HeLa	NNP
cord-322904-9mta0aem	221	16	and	and	CC
cord-322904-9mta0aem	221	17	HEK293A	HEK293A	NNP
cord-322904-9mta0aem	221	18	)	)	-RRB-
cord-322904-9mta0aem	221	19	.	.	.
cord-322904-9mta0aem	222	1	Infection	infection	NN
cord-322904-9mta0aem	222	2	of	of	IN
cord-322904-9mta0aem	222	3	5HT2aR	5HT2aR	NNP
cord-322904-9mta0aem	222	4	expressing	express	VBG
cord-322904-9mta0aem	222	5	cells	cell	NNS
cord-322904-9mta0aem	222	6	is	be	VBZ
cord-322904-9mta0aem	222	7	still	still	RB
cord-322904-9mta0aem	222	8	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	222	9	sensitive	sensitive	JJ
cord-322904-9mta0aem	222	10	indicating	indicate	VBG
cord-322904-9mta0aem	222	11	a	a	DT
cord-322904-9mta0aem	222	12	prominent	prominent	JJ
cord-322904-9mta0aem	222	13	role	role	NN
cord-322904-9mta0aem	222	14	for	for	IN
cord-322904-9mta0aem	222	15	cellular	cellular	JJ
cord-322904-9mta0aem	222	16	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	222	17	in	in	IN
cord-322904-9mta0aem	222	18	infection	infection	NN
cord-322904-9mta0aem	222	19	.	.	.
cord-322904-9mta0aem	223	1	The	the	DT
cord-322904-9mta0aem	223	2	5HT2aR	5ht2ar	CD
cord-322904-9mta0aem	223	3	protein	protein	NN
cord-322904-9mta0aem	223	4	contains	contain	VBZ
cord-322904-9mta0aem	223	5	several	several	JJ
cord-322904-9mta0aem	223	6	potential	potential	JJ
cord-322904-9mta0aem	223	7	glycosylation	glycosylation	NN
cord-322904-9mta0aem	223	8	sites	site	NNS
cord-322904-9mta0aem	223	9	but	but	CC
cord-322904-9mta0aem	223	10	it	-PRON-	PRP
cord-322904-9mta0aem	223	11	is	be	VBZ
cord-322904-9mta0aem	223	12	unclear	unclear	JJ
cord-322904-9mta0aem	223	13	whether	whether	IN
cord-322904-9mta0aem	223	14	the	the	DT
cord-322904-9mta0aem	223	15	sialic	sialic	JJ
cord-322904-9mta0aem	223	16	acid	acid	NN
cord-322904-9mta0aem	223	17	moieties	moiety	NNS
cord-322904-9mta0aem	223	18	responsible	responsible	JJ
cord-322904-9mta0aem	223	19	for	for	IN
cord-322904-9mta0aem	223	20	infection	infection	NN
cord-322904-9mta0aem	223	21	reside	reside	VBP
cord-322904-9mta0aem	223	22	on	on	IN
cord-322904-9mta0aem	223	23	this	this	DT
cord-322904-9mta0aem	223	24	protein	protein	NN
cord-322904-9mta0aem	223	25	or	or	CC
cord-322904-9mta0aem	223	26	on	on	IN
cord-322904-9mta0aem	223	27	other	other	JJ
cord-322904-9mta0aem	223	28	sialic	sialic	NN
cord-322904-9mta0aem	223	29	acid	acid	NN
cord-322904-9mta0aem	223	30	containing	contain	VBG
cord-322904-9mta0aem	223	31	molecules	molecule	NNS
cord-322904-9mta0aem	223	32	such	such	JJ
cord-322904-9mta0aem	223	33	as	as	IN
cord-322904-9mta0aem	223	34	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	223	35	.	.	.
cord-322904-9mta0aem	224	1	One	one	CD
cord-322904-9mta0aem	224	2	group	group	NN
cord-322904-9mta0aem	224	3	has	have	VBZ
cord-322904-9mta0aem	224	4	found	find	VBN
cord-322904-9mta0aem	224	5	that	that	IN
cord-322904-9mta0aem	224	6	JCV	JCV	NNP
cord-322904-9mta0aem	224	7	can	can	MD
cord-322904-9mta0aem	224	8	infect	infect	VB
cord-322904-9mta0aem	224	9	human	human	JJ
cord-322904-9mta0aem	224	10	brain	brain	NN
cord-322904-9mta0aem	224	11	microvascular	microvascular	NN
cord-322904-9mta0aem	224	12	endothelial	endothelial	JJ
cord-322904-9mta0aem	224	13	cells	cell	NNS
cord-322904-9mta0aem	224	14	that	that	WDT
cord-322904-9mta0aem	224	15	lack	lack	VBP
cord-322904-9mta0aem	224	16	the	the	DT
cord-322904-9mta0aem	224	17	5HT2a	5ht2a	CD
cord-322904-9mta0aem	224	18	receptor	receptor	NN
cord-322904-9mta0aem	224	19	(	(	-LRB-
cord-322904-9mta0aem	224	20	Chapagain	Chapagain	NNP
cord-322904-9mta0aem	224	21	et	et	NNP
cord-322904-9mta0aem	224	22	al	al	NNP
cord-322904-9mta0aem	224	23	.	.	NNP
cord-322904-9mta0aem	224	24	,	,	,
cord-322904-9mta0aem	224	25	2007	2007	CD
cord-322904-9mta0aem	224	26	)	)	-RRB-
cord-322904-9mta0aem	224	27	.	.	.
cord-322904-9mta0aem	225	1	Infection	infection	NN
cord-322904-9mta0aem	225	2	is	be	VBZ
cord-322904-9mta0aem	225	3	very	very	RB
cord-322904-9mta0aem	225	4	inefficient	inefficient	JJ
cord-322904-9mta0aem	225	5	but	but	CC
cord-322904-9mta0aem	225	6	the	the	DT
cord-322904-9mta0aem	225	7	results	result	NNS
cord-322904-9mta0aem	225	8	indicate	indicate	VBP
cord-322904-9mta0aem	225	9	that	that	IN
cord-322904-9mta0aem	225	10	virus	virus	NN
cord-322904-9mta0aem	225	11	infection	infection	NN
cord-322904-9mta0aem	225	12	can	can	MD
cord-322904-9mta0aem	225	13	proceed	proceed	VB
cord-322904-9mta0aem	225	14	by	by	IN
cord-322904-9mta0aem	225	15	alternative	alternative	JJ
cord-322904-9mta0aem	225	16	mechanisms	mechanism	NNS
cord-322904-9mta0aem	225	17	on	on	IN
cord-322904-9mta0aem	225	18	some	some	DT
cord-322904-9mta0aem	225	19	cell	cell	NN
cord-322904-9mta0aem	225	20	types	type	NNS
cord-322904-9mta0aem	225	21	.	.	.
cord-322904-9mta0aem	226	1	The	the	DT
cord-322904-9mta0aem	226	2	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	226	3	capsid	capsid	NN
cord-322904-9mta0aem	226	4	consists	consist	VBZ
cord-322904-9mta0aem	226	5	of	of	IN
cord-322904-9mta0aem	226	6	12	12	CD
cord-322904-9mta0aem	226	7	five	five	CD
cord-322904-9mta0aem	226	8	-	-	HYPH
cord-322904-9mta0aem	226	9	coordinated	coordinate	VBN
cord-322904-9mta0aem	226	10	and	and	CC
cord-322904-9mta0aem	226	11	60	60	CD
cord-322904-9mta0aem	226	12	sixcoordinated	sixcoordinated	JJ
cord-322904-9mta0aem	226	13	morphological	morphological	JJ
cord-322904-9mta0aem	226	14	units	unit	NNS
cord-322904-9mta0aem	226	15	that	that	WDT
cord-322904-9mta0aem	226	16	assemble	assemble	VBP
cord-322904-9mta0aem	226	17	into	into	IN
cord-322904-9mta0aem	226	18	a	a	DT
cord-322904-9mta0aem	226	19	T	t	NN
cord-322904-9mta0aem	226	20	=	=	SYM
cord-322904-9mta0aem	226	21	7d	7d	NNP
cord-322904-9mta0aem	226	22	icosahedral	icosahedral	NNP
cord-322904-9mta0aem	226	23	capsid	capsid	NNP
cord-322904-9mta0aem	226	24	(	(	-LRB-
cord-322904-9mta0aem	226	25	Klug	Klug	NNP
cord-322904-9mta0aem	226	26	,	,	,
cord-322904-9mta0aem	226	27	1965	1965	CD
cord-322904-9mta0aem	226	28	)	)	-RRB-
cord-322904-9mta0aem	226	29	.	.	.
cord-322904-9mta0aem	227	1	Icosahedral	Icosahedral	NNP
cord-322904-9mta0aem	227	2	capsid	capsid	NN
cord-322904-9mta0aem	227	3	symmetry	symmetry	NN
cord-322904-9mta0aem	227	4	allows	allow	VBZ
cord-322904-9mta0aem	227	5	the	the	DT
cord-322904-9mta0aem	227	6	virus	virus	NN
cord-322904-9mta0aem	227	7	to	to	TO
cord-322904-9mta0aem	227	8	construct	construct	VB
cord-322904-9mta0aem	227	9	a	a	DT
cord-322904-9mta0aem	227	10	container	container	NN
cord-322904-9mta0aem	227	11	for	for	IN
cord-322904-9mta0aem	227	12	its	-PRON-	PRP$
cord-322904-9mta0aem	227	13	DNA	dna	NN
cord-322904-9mta0aem	227	14	from	from	IN
cord-322904-9mta0aem	227	15	a	a	DT
cord-322904-9mta0aem	227	16	large	large	JJ
cord-322904-9mta0aem	227	17	number	number	NN
cord-322904-9mta0aem	227	18	of	of	IN
cord-322904-9mta0aem	227	19	identical	identical	JJ
cord-322904-9mta0aem	227	20	subunits	subunit	NNS
cord-322904-9mta0aem	227	21	,	,	,
cord-322904-9mta0aem	227	22	eliminating	eliminate	VBG
cord-322904-9mta0aem	227	23	the	the	DT
cord-322904-9mta0aem	227	24	need	need	NN
cord-322904-9mta0aem	227	25	to	to	TO
cord-322904-9mta0aem	227	26	encode	encode	VB
cord-322904-9mta0aem	227	27	many	many	JJ
cord-322904-9mta0aem	227	28	different	different	JJ
cord-322904-9mta0aem	227	29	components	component	NNS
cord-322904-9mta0aem	227	30	(	(	-LRB-
cord-322904-9mta0aem	227	31	Crick	Crick	NNP
cord-322904-9mta0aem	227	32	and	and	CC
cord-322904-9mta0aem	227	33	Watson	Watson	NNP
cord-322904-9mta0aem	227	34	,	,	,
cord-322904-9mta0aem	227	35	1956	1956	CD
cord-322904-9mta0aem	227	36	)	)	-RRB-
cord-322904-9mta0aem	227	37	.	.	.
cord-322904-9mta0aem	228	1	Strict	strict	JJ
cord-322904-9mta0aem	228	2	icosahedral	icosahedral	JJ
cord-322904-9mta0aem	228	3	symmetry	symmetry	NN
cord-322904-9mta0aem	228	4	,	,	,
cord-322904-9mta0aem	228	5	in	in	IN
cord-322904-9mta0aem	228	6	which	which	WDT
cord-322904-9mta0aem	228	7	all	all	DT
cord-322904-9mta0aem	228	8	subunits	subunit	NNS
cord-322904-9mta0aem	228	9	as	as	RB
cord-322904-9mta0aem	228	10	well	well	RB
cord-322904-9mta0aem	228	11	as	as	IN
cord-322904-9mta0aem	228	12	their	-PRON-	PRP$
cord-322904-9mta0aem	228	13	interactions	interaction	NNS
cord-322904-9mta0aem	228	14	with	with	IN
cord-322904-9mta0aem	228	15	each	each	DT
cord-322904-9mta0aem	228	16	other	other	JJ
cord-322904-9mta0aem	228	17	are	be	VBP
cord-322904-9mta0aem	228	18	identical	identical	JJ
cord-322904-9mta0aem	228	19	,	,	,
cord-322904-9mta0aem	228	20	can	can	MD
cord-322904-9mta0aem	228	21	only	only	RB
cord-322904-9mta0aem	228	22	apply	apply	VB
cord-322904-9mta0aem	228	23	to	to	IN
cord-322904-9mta0aem	228	24	capsids	capsid	NNS
cord-322904-9mta0aem	228	25	consisting	consist	VBG
cord-322904-9mta0aem	228	26	of	of	IN
cord-322904-9mta0aem	228	27	no	no	DT
cord-322904-9mta0aem	228	28	more	more	JJR
cord-322904-9mta0aem	228	29	than	than	IN
cord-322904-9mta0aem	228	30	60	60	CD
cord-322904-9mta0aem	228	31	identical	identical	JJ
cord-322904-9mta0aem	228	32	subunits	subunit	NNS
cord-322904-9mta0aem	228	33	.	.	.
cord-322904-9mta0aem	229	1	Some	some	DT
cord-322904-9mta0aem	229	2	exceptionally	exceptionally	RB
cord-322904-9mta0aem	229	3	simple	simple	JJ
cord-322904-9mta0aem	229	4	isocahedral	isocahedral	JJ
cord-322904-9mta0aem	229	5	virus	virus	NN
cord-322904-9mta0aem	229	6	capsids	capsid	NNS
cord-322904-9mta0aem	229	7	are	be	VBP
cord-322904-9mta0aem	229	8	indeed	indeed	RB
cord-322904-9mta0aem	229	9	constructed	construct	VBN
cord-322904-9mta0aem	229	10	from	from	IN
cord-322904-9mta0aem	229	11	60	60	CD
cord-322904-9mta0aem	229	12	identical	identical	JJ
cord-322904-9mta0aem	229	13	subunits	subunit	NNS
cord-322904-9mta0aem	229	14	and	and	CC
cord-322904-9mta0aem	229	15	therefore	therefore	RB
cord-322904-9mta0aem	229	16	possess	possess	VBP
cord-322904-9mta0aem	229	17	strict	strict	JJ
cord-322904-9mta0aem	229	18	icosahedral	icosahedral	JJ
cord-322904-9mta0aem	229	19	symmetry	symmetry	NN
cord-322904-9mta0aem	229	20	(	(	-LRB-
cord-322904-9mta0aem	230	1	Tsao	Tsao	NNP
cord-322904-9mta0aem	230	2	et	et	NNP
cord-322904-9mta0aem	230	3	al	al	NNP
cord-322904-9mta0aem	230	4	.	.	NNP
cord-322904-9mta0aem	230	5	,	,	,
cord-322904-9mta0aem	230	6	1991	1991	CD
cord-322904-9mta0aem	230	7	)	)	-RRB-
cord-322904-9mta0aem	230	8	.	.	.
cord-322904-9mta0aem	231	1	However	however	RB
cord-322904-9mta0aem	231	2	,	,	,
cord-322904-9mta0aem	231	3	the	the	DT
cord-322904-9mta0aem	231	4	need	need	NN
cord-322904-9mta0aem	231	5	for	for	IN
cord-322904-9mta0aem	231	6	more	more	JJR
cord-322904-9mta0aem	231	7	complex	complex	JJ
cord-322904-9mta0aem	231	8	structures	structure	NNS
cord-322904-9mta0aem	231	9	that	that	WDT
cord-322904-9mta0aem	231	10	can	can	MD
cord-322904-9mta0aem	231	11	package	package	VB
cord-322904-9mta0aem	231	12	larger	large	JJR
cord-322904-9mta0aem	231	13	genes	gene	NNS
cord-322904-9mta0aem	231	14	as	as	RB
cord-322904-9mta0aem	231	15	well	well	RB
cord-322904-9mta0aem	231	16	as	as	IN
cord-322904-9mta0aem	231	17	internal	internal	JJ
cord-322904-9mta0aem	231	18	proteins	protein	NNS
cord-322904-9mta0aem	231	19	requires	require	VBZ
cord-322904-9mta0aem	231	20	for	for	IN
cord-322904-9mta0aem	231	21	many	many	JJ
cord-322904-9mta0aem	231	22	viruses	virus	NNS
cord-322904-9mta0aem	231	23	a	a	DT
cord-322904-9mta0aem	231	24	capsid	capsid	NN
cord-322904-9mta0aem	231	25	that	that	WDT
cord-322904-9mta0aem	231	26	can	can	MD
cord-322904-9mta0aem	231	27	not	not	RB
cord-322904-9mta0aem	231	28	be	be	VB
cord-322904-9mta0aem	231	29	formed	form	VBN
cord-322904-9mta0aem	231	30	with	with	IN
cord-322904-9mta0aem	231	31	such	such	PDT
cord-322904-9mta0aem	231	32	a	a	DT
cord-322904-9mta0aem	231	33	small	small	JJ
cord-322904-9mta0aem	231	34	number	number	NN
cord-322904-9mta0aem	231	35	of	of	IN
cord-322904-9mta0aem	231	36	subunits	subunit	NNS
cord-322904-9mta0aem	231	37	.	.	.
cord-322904-9mta0aem	232	1	Therefore	therefore	RB
cord-322904-9mta0aem	232	2	,	,	,
cord-322904-9mta0aem	232	3	most	most	JJS
cord-322904-9mta0aem	232	4	viruses	virus	NNS
cord-322904-9mta0aem	232	5	,	,	,
cord-322904-9mta0aem	232	6	including	include	VBG
cord-322904-9mta0aem	232	7	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	232	8	,	,	,
cord-322904-9mta0aem	232	9	build	build	VB
cord-322904-9mta0aem	232	10	larger	large	JJR
cord-322904-9mta0aem	232	11	capsids	capsid	NNS
cord-322904-9mta0aem	232	12	constructed	construct	VBN
cord-322904-9mta0aem	232	13	from	from	IN
cord-322904-9mta0aem	232	14	multiples	multiple	NNS
cord-322904-9mta0aem	232	15	of	of	IN
cord-322904-9mta0aem	232	16	60	60	CD
cord-322904-9mta0aem	232	17	subunits	subunit	NNS
cord-322904-9mta0aem	232	18	.	.	.
cord-322904-9mta0aem	233	1	In	in	IN
cord-322904-9mta0aem	233	2	these	these	DT
cord-322904-9mta0aem	233	3	capsids	capsid	NNS
cord-322904-9mta0aem	233	4	,	,	,
cord-322904-9mta0aem	233	5	subunits	subunit	NNS
cord-322904-9mta0aem	233	6	must	must	MD
cord-322904-9mta0aem	233	7	be	be	VB
cord-322904-9mta0aem	233	8	joined	join	VBN
cord-322904-9mta0aem	233	9	in	in	IN
cord-322904-9mta0aem	233	10	a	a	DT
cord-322904-9mta0aem	233	11	quasiequivalent	quasiequivalent	NN
cord-322904-9mta0aem	233	12	manner	manner	NN
cord-322904-9mta0aem	233	13	,	,	,
cord-322904-9mta0aem	233	14	meaning	mean	VBG
cord-322904-9mta0aem	233	15	that	that	IN
cord-322904-9mta0aem	233	16	they	-PRON-	PRP
cord-322904-9mta0aem	233	17	do	do	VBP
cord-322904-9mta0aem	233	18	not	not	RB
cord-322904-9mta0aem	233	19	form	form	VB
cord-322904-9mta0aem	233	20	the	the	DT
cord-322904-9mta0aem	233	21	same	same	JJ
cord-322904-9mta0aem	233	22	contacts	contact	NNS
cord-322904-9mta0aem	233	23	with	with	IN
cord-322904-9mta0aem	233	24	their	-PRON-	PRP$
cord-322904-9mta0aem	233	25	neighbors	neighbor	NNS
cord-322904-9mta0aem	233	26	throughout	throughout	IN
cord-322904-9mta0aem	233	27	the	the	DT
cord-322904-9mta0aem	233	28	capsid	capsid	NN
cord-322904-9mta0aem	233	29	,	,	,
cord-322904-9mta0aem	233	30	but	but	CC
cord-322904-9mta0aem	233	31	exhibit	exhibit	VB
cord-322904-9mta0aem	233	32	flexibility	flexibility	NN
cord-322904-9mta0aem	233	33	or	or	CC
cord-322904-9mta0aem	233	34	alternative	alternative	JJ
cord-322904-9mta0aem	233	35	binding	binding	NN
cord-322904-9mta0aem	233	36	modes	mode	NNS
cord-322904-9mta0aem	233	37	to	to	TO
cord-322904-9mta0aem	233	38	accommodate	accommodate	VB
cord-322904-9mta0aem	233	39	local	local	JJ
cord-322904-9mta0aem	233	40	symmetry	symmetry	NN
cord-322904-9mta0aem	233	41	mismatches	mismatch	NNS
cord-322904-9mta0aem	233	42	(	(	-LRB-
cord-322904-9mta0aem	233	43	Caspar	Caspar	NNP
cord-322904-9mta0aem	233	44	and	and	CC
cord-322904-9mta0aem	233	45	Klug	Klug	NNP
cord-322904-9mta0aem	233	46	,	,	,
cord-322904-9mta0aem	233	47	1962	1962	CD
cord-322904-9mta0aem	233	48	)	)	-RRB-
cord-322904-9mta0aem	233	49	.	.	.
cord-322904-9mta0aem	234	1	The	the	DT
cord-322904-9mta0aem	234	2	quasiequivalence	quasiequivalence	NN
cord-322904-9mta0aem	234	3	principle	principle	NN
cord-322904-9mta0aem	234	4	postulated	postulate	VBD
cord-322904-9mta0aem	234	5	that	that	IN
cord-322904-9mta0aem	234	6	the	the	DT
cord-322904-9mta0aem	234	7	pentavalent	pentavalent	NN
cord-322904-9mta0aem	234	8	and	and	CC
cord-322904-9mta0aem	234	9	hexavalent	hexavalent	NN
cord-322904-9mta0aem	234	10	morphological	morphological	JJ
cord-322904-9mta0aem	234	11	units	unit	NNS
cord-322904-9mta0aem	234	12	of	of	IN
cord-322904-9mta0aem	234	13	such	such	JJ
cord-322904-9mta0aem	234	14	larger	large	JJR
cord-322904-9mta0aem	234	15	icosahedral	icosahedral	JJ
cord-322904-9mta0aem	234	16	capsids	capsid	NNS
cord-322904-9mta0aem	234	17	were	be	VBD
cord-322904-9mta0aem	234	18	pentamers	pentamer	NNS
cord-322904-9mta0aem	234	19	and	and	CC
cord-322904-9mta0aem	234	20	hexamers	hexamer	NNS
cord-322904-9mta0aem	234	21	of	of	IN
cord-322904-9mta0aem	234	22	the	the	DT
cord-322904-9mta0aem	234	23	same	same	JJ
cord-322904-9mta0aem	234	24	subunit	subunit	NN
cord-322904-9mta0aem	234	25	.	.	.
cord-322904-9mta0aem	235	1	In	in	IN
cord-322904-9mta0aem	235	2	some	some	DT
cord-322904-9mta0aem	235	3	cases	case	NNS
cord-322904-9mta0aem	235	4	,	,	,
cord-322904-9mta0aem	235	5	this	this	DT
cord-322904-9mta0aem	235	6	has	have	VBZ
cord-322904-9mta0aem	235	7	been	be	VBN
cord-322904-9mta0aem	235	8	proven	prove	VBN
cord-322904-9mta0aem	235	9	correct	correct	JJ
cord-322904-9mta0aem	235	10	,	,	,
cord-322904-9mta0aem	235	11	e.g.	e.g.	RB
cord-322904-9mta0aem	235	12	for	for	IN
cord-322904-9mta0aem	235	13	herpesvirus	herpesvirus	NNP
cord-322904-9mta0aem	235	14	capsids	capsid	NNS
cord-322904-9mta0aem	236	1	(	(	-LRB-
cord-322904-9mta0aem	236	2	Zhou	Zhou	NNP
cord-322904-9mta0aem	236	3	et	et	NNP
cord-322904-9mta0aem	236	4	al	al	NNP
cord-322904-9mta0aem	236	5	.	.	NNP
cord-322904-9mta0aem	236	6	,	,	,
cord-322904-9mta0aem	236	7	2000	2000	CD
cord-322904-9mta0aem	236	8	)	)	-RRB-
cord-322904-9mta0aem	236	9	.	.	.
cord-322904-9mta0aem	237	1	The	the	DT
cord-322904-9mta0aem	237	2	T	T	NNP
cord-322904-9mta0aem	237	3	=	=	SYM
cord-322904-9mta0aem	237	4	7d	7d	NNP
cord-322904-9mta0aem	237	5	icosahedral	icosahedral	NNP
cord-322904-9mta0aem	237	6	capsids	capsid	NNS
cord-322904-9mta0aem	237	7	of	of	IN
cord-322904-9mta0aem	237	8	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	237	9	were	be	VBD
cord-322904-9mta0aem	237	10	therefore	therefore	RB
cord-322904-9mta0aem	237	11	also	also	RB
cord-322904-9mta0aem	237	12	thought	think	VBN
cord-322904-9mta0aem	237	13	to	to	TO
cord-322904-9mta0aem	237	14	consist	consist	VB
cord-322904-9mta0aem	237	15	of	of	IN
cord-322904-9mta0aem	237	16	420	420	CD
cord-322904-9mta0aem	237	17	subunits	subunit	NNS
cord-322904-9mta0aem	237	18	,	,	,
cord-322904-9mta0aem	237	19	grouped	group	VBN
cord-322904-9mta0aem	237	20	into	into	IN
cord-322904-9mta0aem	237	21	12	12	CD
cord-322904-9mta0aem	237	22	pentamers	pentamer	NNS
cord-322904-9mta0aem	237	23	and	and	CC
cord-322904-9mta0aem	237	24	60	60	CD
cord-322904-9mta0aem	237	25	hexamers	hexamer	NNS
cord-322904-9mta0aem	237	26	of	of	IN
cord-322904-9mta0aem	237	27	the	the	DT
cord-322904-9mta0aem	237	28	major	major	JJ
cord-322904-9mta0aem	237	29	capsid	capsid	NN
cord-322904-9mta0aem	237	30	protein	protein	NN
cord-322904-9mta0aem	237	31	VP1	VP1	NNP
cord-322904-9mta0aem	237	32	(	(	-LRB-
cord-322904-9mta0aem	237	33	Finch	Finch	NNP
cord-322904-9mta0aem	237	34	,	,	,
cord-322904-9mta0aem	237	35	1974	1974	CD
cord-322904-9mta0aem	237	36	)	)	-RRB-
cord-322904-9mta0aem	237	37	.	.	.
cord-322904-9mta0aem	238	1	However	however	RB
cord-322904-9mta0aem	238	2	,	,	,
cord-322904-9mta0aem	238	3	the	the	DT
cord-322904-9mta0aem	238	4	crystal	crystal	NN
cord-322904-9mta0aem	238	5	structure	structure	NN
cord-322904-9mta0aem	238	6	of	of	IN
cord-322904-9mta0aem	238	7	the	the	DT
cord-322904-9mta0aem	238	8	mPyV	mpyv	JJ
cord-322904-9mta0aem	238	9	capsid	capsid	NN
cord-322904-9mta0aem	238	10	at	at	IN
cord-322904-9mta0aem	238	11	22.5	22.5	CD
cord-322904-9mta0aem	238	12	Å	å	NN
cord-322904-9mta0aem	238	13	resolution	resolution	NN
cord-322904-9mta0aem	238	14	revealed	reveal	VBD
cord-322904-9mta0aem	238	15	that	that	IN
cord-322904-9mta0aem	238	16	both	both	CC
cord-322904-9mta0aem	238	17	the	the	DT
cord-322904-9mta0aem	238	18	fiveand	fiveand	NN
cord-322904-9mta0aem	238	19	sixcoordinated	sixcoordinated	JJ
cord-322904-9mta0aem	238	20	morphological	morphological	JJ
cord-322904-9mta0aem	238	21	units	unit	NNS
cord-322904-9mta0aem	238	22	of	of	IN
cord-322904-9mta0aem	238	23	the	the	DT
cord-322904-9mta0aem	238	24	capsid	capsid	NN
cord-322904-9mta0aem	238	25	were	be	VBD
cord-322904-9mta0aem	238	26	in	in	IN
cord-322904-9mta0aem	238	27	fact	fact	NN
cord-322904-9mta0aem	238	28	pentamers	pentamer	NNS
cord-322904-9mta0aem	238	29	,	,	,
cord-322904-9mta0aem	238	30	a	a	DT
cord-322904-9mta0aem	238	31	surprising	surprising	JJ
cord-322904-9mta0aem	238	32	result	result	NN
cord-322904-9mta0aem	238	33	that	that	WDT
cord-322904-9mta0aem	238	34	appeared	appear	VBD
cord-322904-9mta0aem	238	35	to	to	TO
cord-322904-9mta0aem	238	36	challenge	challenge	VB
cord-322904-9mta0aem	238	37	the	the	DT
cord-322904-9mta0aem	238	38	concept	concept	NN
cord-322904-9mta0aem	238	39	of	of	IN
cord-322904-9mta0aem	238	40	quasiequivalence	quasiequivalence	NNP
cord-322904-9mta0aem	238	41	as	as	IN
cord-322904-9mta0aem	238	42	the	the	DT
cord-322904-9mta0aem	238	43	same	same	JJ
cord-322904-9mta0aem	238	44	pentameric	pentameric	NN
cord-322904-9mta0aem	238	45	module	module	NN
cord-322904-9mta0aem	238	46	is	be	VBZ
cord-322904-9mta0aem	238	47	able	able	JJ
cord-322904-9mta0aem	238	48	to	to	TO
cord-322904-9mta0aem	238	49	form	form	VB
cord-322904-9mta0aem	238	50	both	both	CC
cord-322904-9mta0aem	238	51	pentavalent	pentavalent	JJ
cord-322904-9mta0aem	238	52	and	and	CC
cord-322904-9mta0aem	238	53	hexavalent	hexavalent	NN
cord-322904-9mta0aem	238	54	contacts	contact	NNS
cord-322904-9mta0aem	238	55	(	(	-LRB-
cord-322904-9mta0aem	238	56	Rayment	Rayment	NNP
cord-322904-9mta0aem	238	57	et	et	NNP
cord-322904-9mta0aem	238	58	al	al	NNP
cord-322904-9mta0aem	238	59	.	.	NNP
cord-322904-9mta0aem	238	60	,	,	,
cord-322904-9mta0aem	238	61	1982	1982	CD
cord-322904-9mta0aem	238	62	)	)	-RRB-
cord-322904-9mta0aem	238	63	.	.	.
cord-322904-9mta0aem	239	1	The	the	DT
cord-322904-9mta0aem	239	2	crystal	crystal	JJ
cord-322904-9mta0aem	239	3	structure	structure	NN
cord-322904-9mta0aem	239	4	of	of	IN
cord-322904-9mta0aem	239	5	SV40	SV40	NNP
cord-322904-9mta0aem	239	6	at	at	IN
cord-322904-9mta0aem	239	7	3.8	3.8	CD
cord-322904-9mta0aem	239	8	Å	å	NN
cord-322904-9mta0aem	239	9	resolution	resolution	NN
cord-322904-9mta0aem	239	10	,	,	,
cord-322904-9mta0aem	239	11	which	which	WDT
cord-322904-9mta0aem	239	12	was	be	VBD
cord-322904-9mta0aem	239	13	determined	determine	VBN
cord-322904-9mta0aem	239	14	almost	almost	RB
cord-322904-9mta0aem	239	15	10	10	CD
cord-322904-9mta0aem	239	16	years	year	NNS
cord-322904-9mta0aem	239	17	later	later	RB
cord-322904-9mta0aem	239	18	finally	finally	RB
cord-322904-9mta0aem	239	19	provided	provide	VBD
cord-322904-9mta0aem	239	20	the	the	DT
cord-322904-9mta0aem	239	21	molecular	molecular	JJ
cord-322904-9mta0aem	239	22	basis	basis	NN
cord-322904-9mta0aem	239	23	for	for	IN
cord-322904-9mta0aem	239	24	the	the	DT
cord-322904-9mta0aem	239	25	unexpected	unexpected	JJ
cord-322904-9mta0aem	239	26	capsid	capsid	NN
cord-322904-9mta0aem	239	27	construction	construction	NN
cord-322904-9mta0aem	239	28	of	of	IN
cord-322904-9mta0aem	239	29	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	239	30	(	(	-LRB-
cord-322904-9mta0aem	239	31	Liddington	Liddington	NNP
cord-322904-9mta0aem	239	32	et	et	FW
cord-322904-9mta0aem	239	33	al	al	NNP
cord-322904-9mta0aem	239	34	.	.	NNP
cord-322904-9mta0aem	239	35	,	,	,
cord-322904-9mta0aem	239	36	1991	1991	CD
cord-322904-9mta0aem	239	37	)	)	-RRB-
cord-322904-9mta0aem	239	38	.	.	.
cord-322904-9mta0aem	240	1	It	-PRON-	PRP
cord-322904-9mta0aem	240	2	revealed	reveal	VBD
cord-322904-9mta0aem	240	3	that	that	IN
cord-322904-9mta0aem	240	4	the	the	DT
cord-322904-9mta0aem	240	5	interpentamer	interpentamer	NNP
cord-322904-9mta0aem	240	6	contacts	contact	NNS
cord-322904-9mta0aem	240	7	are	be	VBP
cord-322904-9mta0aem	240	8	primarily	primarily	RB
cord-322904-9mta0aem	240	9	mediated	mediate	VBN
cord-322904-9mta0aem	240	10	by	by	IN
cord-322904-9mta0aem	240	11	C	c	NN
cord-322904-9mta0aem	240	12	-	-	HYPH
cord-322904-9mta0aem	240	13	terminal	terminal	NN
cord-322904-9mta0aem	240	14	extensions	extension	NNS
cord-322904-9mta0aem	240	15	of	of	IN
cord-322904-9mta0aem	240	16	VP1	VP1	NNP
cord-322904-9mta0aem	240	17	,	,	,
cord-322904-9mta0aem	240	18	termed	termed	JJ
cord-322904-9mta0aem	240	19	arms	arm	NNS
cord-322904-9mta0aem	240	20	,	,	,
cord-322904-9mta0aem	240	21	that	that	WDT
cord-322904-9mta0aem	240	22	protrude	protrude	VBP
cord-322904-9mta0aem	240	23	in	in	IN
cord-322904-9mta0aem	240	24	different	different	JJ
cord-322904-9mta0aem	240	25	directions	direction	NNS
cord-322904-9mta0aem	240	26	from	from	IN
cord-322904-9mta0aem	240	27	each	each	DT
cord-322904-9mta0aem	240	28	VP1	vp1	NN
cord-322904-9mta0aem	240	29	monomer	monomer	NN
cord-322904-9mta0aem	240	30	and	and	CC
cord-322904-9mta0aem	240	31	contact	contact	NN
cord-322904-9mta0aem	240	32	neighboring	neighboring	NN
cord-322904-9mta0aem	240	33	pentamers	pentamer	NNS
cord-322904-9mta0aem	240	34	.	.	.
cord-322904-9mta0aem	241	1	Both	both	DT
cord-322904-9mta0aem	241	2	pentavalent	pentavalent	JJ
cord-322904-9mta0aem	241	3	and	and	CC
cord-322904-9mta0aem	241	4	hexavalent	hexavalent	NN
cord-322904-9mta0aem	241	5	pentamers	pentamer	NNS
cord-322904-9mta0aem	241	6	donate	donate	VBP
cord-322904-9mta0aem	241	7	and	and	CC
cord-322904-9mta0aem	241	8	accept	accept	VBP
cord-322904-9mta0aem	241	9	five	five	CD
cord-322904-9mta0aem	241	10	C	c	NN
cord-322904-9mta0aem	241	11	-	-	HYPH
cord-322904-9mta0aem	241	12	terminal	terminal	NN
cord-322904-9mta0aem	241	13	arms	arm	NNS
cord-322904-9mta0aem	241	14	to	to	TO
cord-322904-9mta0aem	241	15	tie	tie	VB
cord-322904-9mta0aem	241	16	the	the	DT
cord-322904-9mta0aem	241	17	capsid	capsid	NN
cord-322904-9mta0aem	241	18	together	together	RB
cord-322904-9mta0aem	241	19	.	.	.
cord-322904-9mta0aem	242	1	The	the	DT
cord-322904-9mta0aem	242	2	VP1	VP1	NNP
cord-322904-9mta0aem	242	3	pentamer	pentamer	NNP
cord-322904-9mta0aem	242	4	cores	core	NNS
cord-322904-9mta0aem	242	5	and	and	CC
cord-322904-9mta0aem	242	6	the	the	DT
cord-322904-9mta0aem	242	7	contacts	contact	NNS
cord-322904-9mta0aem	242	8	between	between	IN
cord-322904-9mta0aem	242	9	incoming	incoming	JJ
cord-322904-9mta0aem	242	10	arm	arm	NN
cord-322904-9mta0aem	242	11	and	and	CC
cord-322904-9mta0aem	242	12	acceptor	acceptor	NN
cord-322904-9mta0aem	242	13	monomer	monomer	NN
cord-322904-9mta0aem	242	14	are	be	VBP
cord-322904-9mta0aem	242	15	identical	identical	JJ
cord-322904-9mta0aem	242	16	throughout	throughout	IN
cord-322904-9mta0aem	242	17	the	the	DT
cord-322904-9mta0aem	242	18	capsid	capsid	NN
cord-322904-9mta0aem	242	19	,	,	,
cord-322904-9mta0aem	242	20	demonstrating	demonstrate	VBG
cord-322904-9mta0aem	242	21	that	that	IN
cord-322904-9mta0aem	242	22	the	the	DT
cord-322904-9mta0aem	242	23	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	242	24	capsid	capsid	NN
cord-322904-9mta0aem	242	25	also	also	RB
cord-322904-9mta0aem	242	26	uses	use	VBZ
cord-322904-9mta0aem	242	27	a	a	DT
cord-322904-9mta0aem	242	28	form	form	NN
cord-322904-9mta0aem	242	29	of	of	IN
cord-322904-9mta0aem	242	30	quasiequivalence	quasiequivalence	NN
cord-322904-9mta0aem	242	31	as	as	IN
cord-322904-9mta0aem	242	32	the	the	DT
cord-322904-9mta0aem	242	33	basis	basis	NN
cord-322904-9mta0aem	242	34	for	for	IN
cord-322904-9mta0aem	242	35	its	-PRON-	PRP$
cord-322904-9mta0aem	242	36	construction	construction	NN
cord-322904-9mta0aem	242	37	.	.	.
cord-322904-9mta0aem	243	1	Monomeric	monomeric	JJ
cord-322904-9mta0aem	243	2	VP1	vp1	NN
cord-322904-9mta0aem	243	3	is	be	VBZ
cord-322904-9mta0aem	243	4	formed	form	VBN
cord-322904-9mta0aem	243	5	by	by	IN
cord-322904-9mta0aem	243	6	two	two	CD
cord-322904-9mta0aem	243	7	antiparallel	antiparallel	RB
cord-322904-9mta0aem	243	8	β	β	NN
cord-322904-9mta0aem	243	9	-	-	HYPH
cord-322904-9mta0aem	243	10	sheets	sheet	NNS
cord-322904-9mta0aem	243	11	:	:	:
cord-322904-9mta0aem	243	12	a	a	DT
cord-322904-9mta0aem	243	13	sheet	sheet	NN
cord-322904-9mta0aem	243	14	formed	form	VBN
cord-322904-9mta0aem	243	15	by	by	IN
cord-322904-9mta0aem	243	16	strands	strand	NNS
cord-322904-9mta0aem	243	17	B	B	NNP
cord-322904-9mta0aem	243	18	,	,	,
cord-322904-9mta0aem	243	19	I	-PRON-	PRP
cord-322904-9mta0aem	243	20	,	,	,
cord-322904-9mta0aem	243	21	D	D	NNP
cord-322904-9mta0aem	243	22	and	and	CC
cord-322904-9mta0aem	243	23	G	g	NN
cord-322904-9mta0aem	243	24	(	(	-LRB-
cord-322904-9mta0aem	243	25	the	the	DT
cord-322904-9mta0aem	243	26	BIDG	BIDG	NNP
cord-322904-9mta0aem	243	27	sheet	sheet	NN
cord-322904-9mta0aem	243	28	)	)	-RRB-
cord-322904-9mta0aem	243	29	and	and	CC
cord-322904-9mta0aem	243	30	a	a	DT
cord-322904-9mta0aem	243	31	sheet	sheet	NN
cord-322904-9mta0aem	243	32	formed	form	VBN
cord-322904-9mta0aem	243	33	by	by	IN
cord-322904-9mta0aem	243	34	strands	strand	NNS
cord-322904-9mta0aem	243	35	C	C	NNP
cord-322904-9mta0aem	243	36	,	,	,
cord-322904-9mta0aem	243	37	H	H	NNP
cord-322904-9mta0aem	243	38	,	,	,
cord-322904-9mta0aem	243	39	E	E	NNP
cord-322904-9mta0aem	243	40	and	and	CC
cord-322904-9mta0aem	243	41	F	F	NNP
cord-322904-9mta0aem	243	42	(	(	-LRB-
cord-322904-9mta0aem	243	43	the	the	DT
cord-322904-9mta0aem	243	44	CHEF	CHEF	NNP
cord-322904-9mta0aem	243	45	sheet	sheet	NN
cord-322904-9mta0aem	243	46	)	)	-RRB-
cord-322904-9mta0aem	243	47	.	.	.
cord-322904-9mta0aem	244	1	The	the	DT
cord-322904-9mta0aem	244	2	two	two	CD
cord-322904-9mta0aem	244	3	β	β	NN
cord-322904-9mta0aem	244	4	-	-	HYPH
cord-322904-9mta0aem	244	5	sheets	sheet	NNS
cord-322904-9mta0aem	244	6	are	be	VBP
cord-322904-9mta0aem	244	7	organized	organize	VBN
cord-322904-9mta0aem	244	8	into	into	IN
cord-322904-9mta0aem	244	9	a	a	DT
cord-322904-9mta0aem	244	10	jelly	jelly	JJ
cord-322904-9mta0aem	244	11	-	-	HYPH
cord-322904-9mta0aem	244	12	roll	roll	NN
cord-322904-9mta0aem	244	13	fold	fold	NN
cord-322904-9mta0aem	244	14	,	,	,
cord-322904-9mta0aem	244	15	a	a	DT
cord-322904-9mta0aem	244	16	structural	structural	JJ
cord-322904-9mta0aem	244	17	motif	motif	NN
cord-322904-9mta0aem	244	18	that	that	WDT
cord-322904-9mta0aem	244	19	is	be	VBZ
cord-322904-9mta0aem	244	20	quite	quite	RB
cord-322904-9mta0aem	244	21	often	often	RB
cord-322904-9mta0aem	244	22	observed	observe	VBN
cord-322904-9mta0aem	244	23	in	in	IN
cord-322904-9mta0aem	244	24	virus	virus	NN
cord-322904-9mta0aem	244	25	capsid	capsid	NN
cord-322904-9mta0aem	244	26	proteins	protein	NNS
cord-322904-9mta0aem	244	27	but	but	CC
cord-322904-9mta0aem	244	28	rare	rare	JJ
cord-322904-9mta0aem	244	29	in	in	IN
cord-322904-9mta0aem	244	30	non	non	JJ
cord-322904-9mta0aem	244	31	-	-	JJ
cord-322904-9mta0aem	244	32	viral	viral	JJ
cord-322904-9mta0aem	244	33	proteins	protein	NNS
cord-322904-9mta0aem	244	34	.	.	.
cord-322904-9mta0aem	245	1	Each	each	DT
cord-322904-9mta0aem	245	2	incoming	incoming	JJ
cord-322904-9mta0aem	245	3	arm	arm	NN
cord-322904-9mta0aem	245	4	adds	add	VBZ
cord-322904-9mta0aem	245	5	one	one	CD
cord-322904-9mta0aem	245	6	strand	strand	NN
cord-322904-9mta0aem	245	7	(	(	-LRB-
cord-322904-9mta0aem	245	8	J′	J′	NNP
cord-322904-9mta0aem	245	9	)	)	-RRB-
cord-322904-9mta0aem	245	10	to	to	IN
cord-322904-9mta0aem	245	11	the	the	DT
cord-322904-9mta0aem	245	12	edge	edge	NN
cord-322904-9mta0aem	245	13	of	of	IN
cord-322904-9mta0aem	245	14	the	the	DT
cord-322904-9mta0aem	245	15	BIDG	BIDG	NNP
cord-322904-9mta0aem	245	16	sheet	sheet	NN
cord-322904-9mta0aem	245	17	of	of	IN
cord-322904-9mta0aem	245	18	a	a	DT
cord-322904-9mta0aem	245	19	monomer	monomer	NN
cord-322904-9mta0aem	245	20	.	.	.
cord-322904-9mta0aem	246	1	The	the	DT
cord-322904-9mta0aem	246	2	J′	J′	NNP
cord-322904-9mta0aem	246	3	strand	strand	NN
cord-322904-9mta0aem	246	4	is	be	VBZ
cord-322904-9mta0aem	246	5	then	then	RB
cord-322904-9mta0aem	246	6	fixed	fix	VBN
cord-322904-9mta0aem	246	7	by	by	IN
cord-322904-9mta0aem	246	8	the	the	DT
cord-322904-9mta0aem	246	9	N	n	CD
cord-322904-9mta0aem	246	10	-	-	HYPH
cord-322904-9mta0aem	246	11	terminus	terminus	NN
cord-322904-9mta0aem	246	12	of	of	IN
cord-322904-9mta0aem	246	13	the	the	DT
cord-322904-9mta0aem	246	14	accepting	accept	VBG
cord-322904-9mta0aem	246	15	monomer	monomer	NN
cord-322904-9mta0aem	246	16	,	,	,
cord-322904-9mta0aem	246	17	which	which	WDT
cord-322904-9mta0aem	246	18	acts	act	VBZ
cord-322904-9mta0aem	246	19	as	as	IN
cord-322904-9mta0aem	246	20	a	a	DT
cord-322904-9mta0aem	246	21	clamp	clamp	NN
cord-322904-9mta0aem	246	22	by	by	IN
cord-322904-9mta0aem	246	23	adding	add	VBG
cord-322904-9mta0aem	246	24	a	a	DT
cord-322904-9mta0aem	246	25	short	short	JJ
cord-322904-9mta0aem	246	26	helix	helix	NN
cord-322904-9mta0aem	246	27	and	and	CC
cord-322904-9mta0aem	246	28	a	a	DT
cord-322904-9mta0aem	246	29	final	final	JJ
cord-322904-9mta0aem	246	30	β	β	NN
cord-322904-9mta0aem	246	31	-	-	HYPH
cord-322904-9mta0aem	246	32	strand	strand	NN
cord-322904-9mta0aem	246	33	(	(	-LRB-
cord-322904-9mta0aem	246	34	A	a	NN
cord-322904-9mta0aem	246	35	)	)	-RRB-
cord-322904-9mta0aem	246	36	to	to	IN
cord-322904-9mta0aem	246	37	the	the	DT
cord-322904-9mta0aem	246	38	sheet	sheet	NN
cord-322904-9mta0aem	246	39	next	next	RB
cord-322904-9mta0aem	246	40	to	to	IN
cord-322904-9mta0aem	246	41	the	the	DT
cord-322904-9mta0aem	246	42	J′	J′	NNP
cord-322904-9mta0aem	246	43	strand	strand	NN
cord-322904-9mta0aem	246	44	.	.	.
cord-322904-9mta0aem	247	1	The	the	DT
cord-322904-9mta0aem	247	2	assembled	assembled	JJ
cord-322904-9mta0aem	247	3	structure	structure	NN
cord-322904-9mta0aem	247	4	is	be	VBZ
cord-322904-9mta0aem	247	5	further	further	RB
cord-322904-9mta0aem	247	6	stabilized	stabilize	VBN
cord-322904-9mta0aem	247	7	by	by	IN
cord-322904-9mta0aem	247	8	two	two	CD
cord-322904-9mta0aem	247	9	calcium	calcium	NN
cord-322904-9mta0aem	247	10	ions	ion	NNS
cord-322904-9mta0aem	247	11	.	.	.
cord-322904-9mta0aem	248	1	These	these	DT
cord-322904-9mta0aem	248	2	findings	finding	NNS
cord-322904-9mta0aem	248	3	were	be	VBD
cord-322904-9mta0aem	248	4	confirmed	confirm	VBN
cord-322904-9mta0aem	248	5	for	for	IN
cord-322904-9mta0aem	248	6	mPyV	mPyV	NNP
cord-322904-9mta0aem	248	7	and	and	CC
cord-322904-9mta0aem	248	8	are	be	VBP
cord-322904-9mta0aem	248	9	thought	think	VBN
cord-322904-9mta0aem	248	10	to	to	TO
cord-322904-9mta0aem	248	11	hold	hold	VB
cord-322904-9mta0aem	248	12	true	true	JJ
cord-322904-9mta0aem	248	13	for	for	IN
cord-322904-9mta0aem	248	14	the	the	DT
cord-322904-9mta0aem	248	15	other	other	JJ
cord-322904-9mta0aem	248	16	members	member	NNS
cord-322904-9mta0aem	248	17	of	of	IN
cord-322904-9mta0aem	248	18	the	the	DT
cord-322904-9mta0aem	248	19	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	248	20	family	family	NN
cord-322904-9mta0aem	248	21	as	as	RB
cord-322904-9mta0aem	248	22	well	well	RB
cord-322904-9mta0aem	248	23	because	because	IN
cord-322904-9mta0aem	248	24	of	of	IN
cord-322904-9mta0aem	248	25	conservation	conservation	NN
cord-322904-9mta0aem	248	26	of	of	IN
cord-322904-9mta0aem	248	27	the	the	DT
cord-322904-9mta0aem	248	28	key	key	JJ
cord-322904-9mta0aem	248	29	contact	contact	NN
cord-322904-9mta0aem	248	30	residues	residue	NNS
cord-322904-9mta0aem	248	31	(	(	-LRB-
cord-322904-9mta0aem	248	32	Stehle	Stehle	NNP
cord-322904-9mta0aem	248	33	et	et	FW
cord-322904-9mta0aem	248	34	al	al	NNP
cord-322904-9mta0aem	248	35	.	.	NNP
cord-322904-9mta0aem	248	36	,	,	,
cord-322904-9mta0aem	248	37	1996	1996	CD
cord-322904-9mta0aem	248	38	;	;	:
cord-322904-9mta0aem	248	39	Stehle	Stehle	NNP
cord-322904-9mta0aem	248	40	et	et	FW
cord-322904-9mta0aem	248	41	al	al	NNP
cord-322904-9mta0aem	248	42	.	.	NNP
cord-322904-9mta0aem	248	43	,	,	,
cord-322904-9mta0aem	248	44	1994	1994	CD
cord-322904-9mta0aem	248	45	)	)	-RRB-
cord-322904-9mta0aem	248	46	.	.	.
cord-322904-9mta0aem	249	1	Structural	structural	JJ
cord-322904-9mta0aem	249	2	studies	study	NNS
cord-322904-9mta0aem	249	3	of	of	IN
cord-322904-9mta0aem	249	4	unassembled	unassemble	VBN
cord-322904-9mta0aem	249	5	,	,	,
cord-322904-9mta0aem	249	6	or	or	CC
cord-322904-9mta0aem	249	7	"	"	``
cord-322904-9mta0aem	249	8	free	free	JJ
cord-322904-9mta0aem	249	9	"	"	''
cord-322904-9mta0aem	249	10	,	,	,
cord-322904-9mta0aem	249	11	pentamers	pentamer	NNS
cord-322904-9mta0aem	249	12	that	that	WDT
cord-322904-9mta0aem	249	13	lack	lack	VBP
cord-322904-9mta0aem	249	14	their	-PRON-	PRP$
cord-322904-9mta0aem	249	15	C	c	NN
cord-322904-9mta0aem	249	16	-	-	HYPH
cord-322904-9mta0aem	249	17	terminal	terminal	NN
cord-322904-9mta0aem	249	18	arms	arm	NNS
cord-322904-9mta0aem	249	19	provide	provide	VBP
cord-322904-9mta0aem	249	20	insight	insight	NN
cord-322904-9mta0aem	249	21	into	into	IN
cord-322904-9mta0aem	249	22	one	one	CD
cord-322904-9mta0aem	249	23	aspect	aspect	NN
cord-322904-9mta0aem	249	24	of	of	IN
cord-322904-9mta0aem	249	25	capsid	capsid	NN
cord-322904-9mta0aem	249	26	assembly	assembly	NN
cord-322904-9mta0aem	250	1	(	(	-LRB-
cord-322904-9mta0aem	250	2	Neu	Neu	NNP
cord-322904-9mta0aem	250	3	et	et	FW
cord-322904-9mta0aem	250	4	al	al	NNP
cord-322904-9mta0aem	250	5	.	.	NNP
cord-322904-9mta0aem	250	6	,	,	,
cord-322904-9mta0aem	250	7	2008	2008	CD
cord-322904-9mta0aem	250	8	;	;	.
cord-322904-9mta0aem	251	1	Stehle	Stehle	NNP
cord-322904-9mta0aem	251	2	and	and	CC
cord-322904-9mta0aem	251	3	Harrison	Harrison	NNP
cord-322904-9mta0aem	251	4	,	,	,
cord-322904-9mta0aem	251	5	1997	1997	CD
cord-322904-9mta0aem	251	6	)	)	-RRB-
cord-322904-9mta0aem	251	7	.	.	.
cord-322904-9mta0aem	252	1	The	the	DT
cord-322904-9mta0aem	252	2	only	only	JJ
cord-322904-9mta0aem	252	3	structural	structural	JJ
cord-322904-9mta0aem	252	4	change	change	NN
cord-322904-9mta0aem	252	5	between	between	IN
cord-322904-9mta0aem	252	6	free	free	JJ
cord-322904-9mta0aem	252	7	VP1	vp1	NN
cord-322904-9mta0aem	252	8	and	and	CC
cord-322904-9mta0aem	252	9	VP1	vp1	NN
cord-322904-9mta0aem	252	10	in	in	IN
cord-322904-9mta0aem	252	11	the	the	DT
cord-322904-9mta0aem	252	12	context	context	NN
cord-322904-9mta0aem	252	13	of	of	IN
cord-322904-9mta0aem	252	14	the	the	DT
cord-322904-9mta0aem	252	15	capsid	capsid	NN
cord-322904-9mta0aem	252	16	is	be	VBZ
cord-322904-9mta0aem	252	17	a	a	DT
cord-322904-9mta0aem	252	18	rearrangement	rearrangement	NN
cord-322904-9mta0aem	252	19	at	at	IN
cord-322904-9mta0aem	252	20	the	the	DT
cord-322904-9mta0aem	252	21	N	n	CD
cord-322904-9mta0aem	252	22	-	-	HYPH
cord-322904-9mta0aem	252	23	terminus	terminus	NN
cord-322904-9mta0aem	252	24	,	,	,
cord-322904-9mta0aem	252	25	which	which	WDT
cord-322904-9mta0aem	252	26	forms	form	VBZ
cord-322904-9mta0aem	252	27	a	a	DT
cord-322904-9mta0aem	252	28	helix	helix	NN
cord-322904-9mta0aem	252	29	fixing	fix	VBG
cord-322904-9mta0aem	252	30	the	the	DT
cord-322904-9mta0aem	252	31	incoming	incoming	JJ
cord-322904-9mta0aem	252	32	arm	arm	NN
cord-322904-9mta0aem	252	33	in	in	IN
cord-322904-9mta0aem	252	34	the	the	DT
cord-322904-9mta0aem	252	35	capsid	capsid	NN
cord-322904-9mta0aem	252	36	.	.	.
cord-322904-9mta0aem	253	1	In	in	IN
cord-322904-9mta0aem	253	2	free	free	JJ
cord-322904-9mta0aem	253	3	pentamers	pentamer	NNS
cord-322904-9mta0aem	253	4	,	,	,
cord-322904-9mta0aem	253	5	this	this	DT
cord-322904-9mta0aem	253	6	part	part	NN
cord-322904-9mta0aem	253	7	of	of	IN
cord-322904-9mta0aem	253	8	VP1	VP1	NNP
cord-322904-9mta0aem	253	9	forms	form	VBZ
cord-322904-9mta0aem	253	10	a	a	DT
cord-322904-9mta0aem	253	11	β	β	NN
cord-322904-9mta0aem	253	12	-	-	HYPH
cord-322904-9mta0aem	253	13	strand	strand	NN
cord-322904-9mta0aem	253	14	that	that	WDT
cord-322904-9mta0aem	253	15	aligns	align	VBZ
cord-322904-9mta0aem	253	16	with	with	IN
cord-322904-9mta0aem	253	17	the	the	DT
cord-322904-9mta0aem	253	18	G	g	NN
cord-322904-9mta0aem	253	19	strand	strand	NN
cord-322904-9mta0aem	253	20	and	and	CC
cord-322904-9mta0aem	253	21	contacts	contact	VBZ
cord-322904-9mta0aem	253	22	residues	residue	NNS
cord-322904-9mta0aem	253	23	at	at	IN
cord-322904-9mta0aem	253	24	the	the	DT
cord-322904-9mta0aem	253	25	beginning	beginning	NN
cord-322904-9mta0aem	253	26	of	of	IN
cord-322904-9mta0aem	253	27	the	the	DT
cord-322904-9mta0aem	253	28	C	C	NNP
cord-322904-9mta0aem	253	29	-	-	HYPH
cord-322904-9mta0aem	253	30	terminal	terminal	NN
cord-322904-9mta0aem	253	31	arm	arm	NN
cord-322904-9mta0aem	253	32	.	.	.
cord-322904-9mta0aem	254	1	One	one	CD
cord-322904-9mta0aem	254	2	likely	likely	JJ
cord-322904-9mta0aem	254	3	interpretation	interpretation	NN
cord-322904-9mta0aem	254	4	of	of	IN
cord-322904-9mta0aem	254	5	this	this	DT
cord-322904-9mta0aem	254	6	finding	finding	NN
cord-322904-9mta0aem	254	7	is	be	VBZ
cord-322904-9mta0aem	254	8	that	that	IN
cord-322904-9mta0aem	254	9	this	this	DT
cord-322904-9mta0aem	254	10	arrangement	arrangement	NN
cord-322904-9mta0aem	254	11	serves	serve	VBZ
cord-322904-9mta0aem	254	12	to	to	TO
cord-322904-9mta0aem	254	13	guide	guide	VB
cord-322904-9mta0aem	254	14	the	the	DT
cord-322904-9mta0aem	254	15	C	C	NNP
cord-322904-9mta0aem	254	16	-	-	HYPH
cord-322904-9mta0aem	254	17	terminal	terminal	NN
cord-322904-9mta0aem	254	18	arm	arm	NN
cord-322904-9mta0aem	254	19	away	away	RB
cord-322904-9mta0aem	254	20	from	from	IN
cord-322904-9mta0aem	254	21	its	-PRON-	PRP$
cord-322904-9mta0aem	254	22	own	own	JJ
cord-322904-9mta0aem	254	23	subunit	subunit	NN
cord-322904-9mta0aem	254	24	,	,	,
cord-322904-9mta0aem	254	25	thereby	thereby	RB
cord-322904-9mta0aem	254	26	preventing	prevent	VBG
cord-322904-9mta0aem	254	27	misassembly	misassembly	RB
cord-322904-9mta0aem	254	28	of	of	IN
cord-322904-9mta0aem	254	29	the	the	DT
cord-322904-9mta0aem	254	30	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	254	31	capsids	capsids	NNP
cord-322904-9mta0aem	254	32	.	.	.
cord-322904-9mta0aem	255	1	Receptor	receptor	NN
cord-322904-9mta0aem	255	2	binding	binding	NN
cord-322904-9mta0aem	255	3	by	by	IN
cord-322904-9mta0aem	255	4	mPyV	mPyV	NNP
cord-322904-9mta0aem	255	5	was	be	VBD
cord-322904-9mta0aem	255	6	structurally	structurally	RB
cord-322904-9mta0aem	255	7	investigated	investigate	VBN
cord-322904-9mta0aem	255	8	early	early	RB
cord-322904-9mta0aem	255	9	on	on	RB
cord-322904-9mta0aem	255	10	for	for	IN
cord-322904-9mta0aem	255	11	whole	whole	JJ
cord-322904-9mta0aem	255	12	virions	virion	NNS
cord-322904-9mta0aem	255	13	as	as	RB
cord-322904-9mta0aem	255	14	well	well	RB
cord-322904-9mta0aem	255	15	as	as	IN
cord-322904-9mta0aem	255	16	for	for	IN
cord-322904-9mta0aem	255	17	VP1	VP1	NNP
cord-322904-9mta0aem	255	18	pentamers	pentamer	NNS
cord-322904-9mta0aem	256	1	(	(	-LRB-
cord-322904-9mta0aem	256	2	Stehle	Stehle	NNP
cord-322904-9mta0aem	256	3	et	et	FW
cord-322904-9mta0aem	256	4	al	al	NNP
cord-322904-9mta0aem	256	5	.	.	NNP
cord-322904-9mta0aem	256	6	,	,	,
cord-322904-9mta0aem	256	7	1996	1996	CD
cord-322904-9mta0aem	256	8	;	;	:
cord-322904-9mta0aem	256	9	Stehle	Stehle	NNP
cord-322904-9mta0aem	256	10	and	and	CC
cord-322904-9mta0aem	256	11	Harrison	Harrison	NNP
cord-322904-9mta0aem	256	12	,	,	,
cord-322904-9mta0aem	256	13	1997	1997	CD
cord-322904-9mta0aem	256	14	;	;	:
cord-322904-9mta0aem	256	15	Stehle	Stehle	NNP
cord-322904-9mta0aem	256	16	et	et	FW
cord-322904-9mta0aem	256	17	al	al	NNP
cord-322904-9mta0aem	256	18	.	.	NNP
cord-322904-9mta0aem	256	19	,	,	,
cord-322904-9mta0aem	256	20	1994	1994	CD
cord-322904-9mta0aem	256	21	)	)	-RRB-
cord-322904-9mta0aem	256	22	as	as	IN
cord-322904-9mta0aem	256	23	it	-PRON-	PRP
cord-322904-9mta0aem	256	24	was	be	VBD
cord-322904-9mta0aem	256	25	known	know	VBN
cord-322904-9mta0aem	256	26	that	that	IN
cord-322904-9mta0aem	256	27	mPyV	mpyv	NN
cord-322904-9mta0aem	256	28	bound	bind	VBN
cord-322904-9mta0aem	256	29	α2,3-linked	α2,3-linked	CD
cord-322904-9mta0aem	256	30	sialic	sialic	JJ
cord-322904-9mta0aem	256	31	acid	acid	NN
cord-322904-9mta0aem	256	32	(	(	-LRB-
cord-322904-9mta0aem	256	33	Cahan	Cahan	NNP
cord-322904-9mta0aem	256	34	et	et	NNP
cord-322904-9mta0aem	256	35	al	al	NNP
cord-322904-9mta0aem	256	36	.	.	NNP
cord-322904-9mta0aem	256	37	,	,	,
cord-322904-9mta0aem	256	38	1983	1983	CD
cord-322904-9mta0aem	256	39	;	;	.
cord-322904-9mta0aem	257	1	Fried	fry	VBN
cord-322904-9mta0aem	257	2	et	et	FW
cord-322904-9mta0aem	257	3	al	al	NNP
cord-322904-9mta0aem	257	4	.	.	NNP
cord-322904-9mta0aem	257	5	,	,	,
cord-322904-9mta0aem	257	6	1981	1981	CD
cord-322904-9mta0aem	257	7	)	)	-RRB-
cord-322904-9mta0aem	257	8	.	.	.
cord-322904-9mta0aem	258	1	The	the	DT
cord-322904-9mta0aem	258	2	sialylated	sialylated	JJ
cord-322904-9mta0aem	258	3	oligosaccharides	oligosaccharide	NNS
cord-322904-9mta0aem	258	4	used	use	VBN
cord-322904-9mta0aem	258	5	as	as	IN
cord-322904-9mta0aem	258	6	receptor	receptor	NN
cord-322904-9mta0aem	258	7	mimics	mimic	VBZ
cord-322904-9mta0aem	258	8	bound	bind	VBN
cord-322904-9mta0aem	258	9	to	to	IN
cord-322904-9mta0aem	258	10	VP1	vp1	NN
cord-322904-9mta0aem	258	11	in	in	IN
cord-322904-9mta0aem	258	12	shallow	shallow	JJ
cord-322904-9mta0aem	258	13	pockets	pocket	NNS
cord-322904-9mta0aem	258	14	on	on	IN
cord-322904-9mta0aem	258	15	the	the	DT
cord-322904-9mta0aem	258	16	outer	outer	JJ
cord-322904-9mta0aem	258	17	surface	surface	NN
cord-322904-9mta0aem	258	18	of	of	IN
cord-322904-9mta0aem	258	19	the	the	DT
cord-322904-9mta0aem	258	20	pentamers	pentamer	NNS
cord-322904-9mta0aem	258	21	.	.	.
cord-322904-9mta0aem	259	1	These	these	DT
cord-322904-9mta0aem	259	2	sialylated	sialylate	VBN
cord-322904-9mta0aem	259	3	oligosaccharides	oligosaccharide	NNS
cord-322904-9mta0aem	259	4	were	be	VBD
cord-322904-9mta0aem	259	5	later	later	RB
cord-322904-9mta0aem	259	6	found	find	VBN
cord-322904-9mta0aem	259	7	to	to	TO
cord-322904-9mta0aem	259	8	be	be	VB
cord-322904-9mta0aem	259	9	portions	portion	NNS
cord-322904-9mta0aem	259	10	of	of	IN
cord-322904-9mta0aem	259	11	the	the	DT
cord-322904-9mta0aem	259	12	GD1a	GD1a	NNP
cord-322904-9mta0aem	259	13	and	and	CC
cord-322904-9mta0aem	259	14	GT1b	GT1b	NNP
cord-322904-9mta0aem	259	15	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	259	16	,	,	,
cord-322904-9mta0aem	259	17	which	which	WDT
cord-322904-9mta0aem	259	18	are	be	VBP
cord-322904-9mta0aem	259	19	the	the	DT
cord-322904-9mta0aem	259	20	physiologic	physiologic	JJ
cord-322904-9mta0aem	259	21	receptors	receptor	NNS
cord-322904-9mta0aem	259	22	for	for	IN
cord-322904-9mta0aem	259	23	mPyV	mPyV	NNP
cord-322904-9mta0aem	259	24	(	(	-LRB-
cord-322904-9mta0aem	259	25	Tsai	Tsai	NNP
cord-322904-9mta0aem	259	26	et	et	NNP
cord-322904-9mta0aem	259	27	al	al	NNP
cord-322904-9mta0aem	259	28	.	.	NNP
cord-322904-9mta0aem	259	29	,	,	,
cord-322904-9mta0aem	259	30	2003	2003	CD
cord-322904-9mta0aem	259	31	)	)	-RRB-
cord-322904-9mta0aem	259	32	.	.	.
cord-322904-9mta0aem	260	1	The	the	DT
cord-322904-9mta0aem	260	2	same	same	JJ
cord-322904-9mta0aem	260	3	group	group	NN
cord-322904-9mta0aem	260	4	also	also	RB
cord-322904-9mta0aem	260	5	identified	identify	VBD
cord-322904-9mta0aem	260	6	the	the	DT
cord-322904-9mta0aem	260	7	ganglioside	ganglioside	NN
cord-322904-9mta0aem	260	8	GM1	GM1	NNP
cord-322904-9mta0aem	260	9	as	as	IN
cord-322904-9mta0aem	260	10	a	a	DT
cord-322904-9mta0aem	260	11	receptor	receptor	NN
cord-322904-9mta0aem	260	12	for	for	IN
cord-322904-9mta0aem	260	13	SV40	SV40	NNP
cord-322904-9mta0aem	261	1	(	(	-LRB-
cord-322904-9mta0aem	261	2	Tsai	Tsai	NNP
cord-322904-9mta0aem	261	3	et	et	NNP
cord-322904-9mta0aem	261	4	al	al	NNP
cord-322904-9mta0aem	261	5	.	.	NNP
cord-322904-9mta0aem	261	6	,	,	,
cord-322904-9mta0aem	261	7	2003	2003	CD
cord-322904-9mta0aem	261	8	)	)	-RRB-
cord-322904-9mta0aem	261	9	.	.	.
cord-322904-9mta0aem	262	1	The	the	DT
cord-322904-9mta0aem	262	2	structural	structural	JJ
cord-322904-9mta0aem	262	3	and	and	CC
cord-322904-9mta0aem	262	4	functional	functional	JJ
cord-322904-9mta0aem	262	5	characterization	characterization	NN
cord-322904-9mta0aem	262	6	of	of	IN
cord-322904-9mta0aem	262	7	the	the	DT
cord-322904-9mta0aem	262	8	interaction	interaction	NN
cord-322904-9mta0aem	262	9	between	between	IN
cord-322904-9mta0aem	262	10	SV40	SV40	NNP
cord-322904-9mta0aem	262	11	and	and	CC
cord-322904-9mta0aem	262	12	GM1	GM1	NNP
cord-322904-9mta0aem	262	13	was	be	VBD
cord-322904-9mta0aem	262	14	made	make	VBN
cord-322904-9mta0aem	262	15	possible	possible	JJ
cord-322904-9mta0aem	262	16	because	because	IN
cord-322904-9mta0aem	262	17	a	a	DT
cord-322904-9mta0aem	262	18	wide	wide	JJ
cord-322904-9mta0aem	262	19	variety	variety	NN
cord-322904-9mta0aem	262	20	of	of	IN
cord-322904-9mta0aem	262	21	glycans	glycan	NNS
cord-322904-9mta0aem	262	22	were	be	VBD
cord-322904-9mta0aem	262	23	available	available	JJ
cord-322904-9mta0aem	262	24	for	for	IN
cord-322904-9mta0aem	262	25	defining	define	VBG
cord-322904-9mta0aem	262	26	receptor	receptor	NN
cord-322904-9mta0aem	262	27	specificity	specificity	NN
cord-322904-9mta0aem	262	28	and	and	CC
cord-322904-9mta0aem	262	29	as	as	IN
cord-322904-9mta0aem	262	30	the	the	DT
cord-322904-9mta0aem	262	31	oligosaccharide	oligosaccharide	NN
cord-322904-9mta0aem	262	32	portion	portion	NN
cord-322904-9mta0aem	262	33	of	of	IN
cord-322904-9mta0aem	262	34	GM1	GM1	NNP
cord-322904-9mta0aem	262	35	was	be	VBD
cord-322904-9mta0aem	262	36	available	available	JJ
cord-322904-9mta0aem	262	37	in	in	IN
cord-322904-9mta0aem	262	38	amounts	amount	NNS
cord-322904-9mta0aem	262	39	sufficient	sufficient	JJ
cord-322904-9mta0aem	262	40	for	for	IN
cord-322904-9mta0aem	262	41	structural	structural	JJ
cord-322904-9mta0aem	262	42	analysis	analysis	NN
cord-322904-9mta0aem	263	1	(	(	-LRB-
cord-322904-9mta0aem	263	2	Campanero	Campanero	NNP
cord-322904-9mta0aem	263	3	-	-	HYPH
cord-322904-9mta0aem	263	4	Rhodes	Rhodes	NNP
cord-322904-9mta0aem	263	5	et	et	NNP
cord-322904-9mta0aem	263	6	al	al	NNP
cord-322904-9mta0aem	263	7	.	.	NNP
cord-322904-9mta0aem	263	8	,	,	,
cord-322904-9mta0aem	263	9	2007	2007	CD
cord-322904-9mta0aem	264	1	;	;	:
cord-322904-9mta0aem	264	2	Neu	Neu	NNP
cord-322904-9mta0aem	264	3	et	et	FW
cord-322904-9mta0aem	264	4	al	al	NNP
cord-322904-9mta0aem	264	5	.	.	NNP
cord-322904-9mta0aem	264	6	,	,	,
cord-322904-9mta0aem	264	7	2008	2008	CD
cord-322904-9mta0aem	264	8	)	)	-RRB-
cord-322904-9mta0aem	264	9	.	.	.
cord-322904-9mta0aem	265	1	As	as	IN
cord-322904-9mta0aem	265	2	an	an	DT
cord-322904-9mta0aem	265	3	increasing	increase	VBG
cord-322904-9mta0aem	265	4	amount	amount	NN
cord-322904-9mta0aem	265	5	of	of	IN
cord-322904-9mta0aem	265	6	structural	structural	JJ
cord-322904-9mta0aem	265	7	information	information	NN
cord-322904-9mta0aem	265	8	on	on	IN
cord-322904-9mta0aem	265	9	viral	viral	JJ
cord-322904-9mta0aem	265	10	attachment	attachment	NN
cord-322904-9mta0aem	265	11	proteins	protein	NNS
cord-322904-9mta0aem	265	12	in	in	IN
cord-322904-9mta0aem	265	13	complex	complex	NN
cord-322904-9mta0aem	265	14	with	with	IN
cord-322904-9mta0aem	265	15	sialylated	sialylated	JJ
cord-322904-9mta0aem	265	16	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	265	17	receptors	receptor	NNS
cord-322904-9mta0aem	265	18	has	have	VBZ
cord-322904-9mta0aem	265	19	become	become	VBN
cord-322904-9mta0aem	265	20	available	available	JJ
cord-322904-9mta0aem	265	21	in	in	IN
cord-322904-9mta0aem	265	22	recent	recent	JJ
cord-322904-9mta0aem	265	23	years	year	NNS
cord-322904-9mta0aem	265	24	,	,	,
cord-322904-9mta0aem	265	25	we	-PRON-	PRP
cord-322904-9mta0aem	265	26	will	will	MD
cord-322904-9mta0aem	265	27	focus	focus	VB
cord-322904-9mta0aem	265	28	the	the	DT
cord-322904-9mta0aem	265	29	remainder	remainder	NN
cord-322904-9mta0aem	265	30	of	of	IN
cord-322904-9mta0aem	265	31	this	this	DT
cord-322904-9mta0aem	265	32	chapter	chapter	NN
cord-322904-9mta0aem	265	33	on	on	IN
cord-322904-9mta0aem	265	34	those	those	DT
cord-322904-9mta0aem	265	35	findings	finding	NNS
cord-322904-9mta0aem	265	36	and	and	CC
cord-322904-9mta0aem	265	37	their	-PRON-	PRP$
cord-322904-9mta0aem	265	38	general	general	JJ
cord-322904-9mta0aem	265	39	implications	implication	NNS
cord-322904-9mta0aem	265	40	.	.	.
cord-322904-9mta0aem	266	1	Sialic	Sialic	NNP
cord-322904-9mta0aem	266	2	acids	acid	NNS
cord-322904-9mta0aem	266	3	are	be	VBP
cord-322904-9mta0aem	266	4	present	present	JJ
cord-322904-9mta0aem	266	5	on	on	IN
cord-322904-9mta0aem	266	6	virtually	virtually	RB
cord-322904-9mta0aem	266	7	every	every	DT
cord-322904-9mta0aem	266	8	cell	cell	NN
cord-322904-9mta0aem	266	9	type	type	NN
cord-322904-9mta0aem	266	10	in	in	IN
cord-322904-9mta0aem	266	11	higher	high	JJR
cord-322904-9mta0aem	266	12	vertebrates	vertebrate	NNS
cord-322904-9mta0aem	266	13	(	(	-LRB-
cord-322904-9mta0aem	266	14	Varki	Varki	NNP
cord-322904-9mta0aem	266	15	,	,	,
cord-322904-9mta0aem	266	16	2008	2008	CD
cord-322904-9mta0aem	266	17	)	)	-RRB-
cord-322904-9mta0aem	266	18	.	.	.
cord-322904-9mta0aem	267	1	Sialylation	sialylation	NN
cord-322904-9mta0aem	267	2	is	be	VBZ
cord-322904-9mta0aem	267	3	a	a	DT
cord-322904-9mta0aem	267	4	terminal	terminal	JJ
cord-322904-9mta0aem	267	5	modification	modification	NN
cord-322904-9mta0aem	267	6	on	on	IN
cord-322904-9mta0aem	267	7	glycolipids	glycolipid	NNS
cord-322904-9mta0aem	267	8	and	and	CC
cord-322904-9mta0aem	267	9	glycoproteins	glycoprotein	NNS
cord-322904-9mta0aem	267	10	,	,	,
cord-322904-9mta0aem	267	11	and	and	CC
cord-322904-9mta0aem	267	12	sialic	sialic	JJ
cord-322904-9mta0aem	267	13	acids	acid	NNS
cord-322904-9mta0aem	267	14	can	can	MD
cord-322904-9mta0aem	267	15	be	be	VB
cord-322904-9mta0aem	267	16	attached	attach	VBN
cord-322904-9mta0aem	267	17	to	to	IN
cord-322904-9mta0aem	267	18	a	a	DT
cord-322904-9mta0aem	267	19	variety	variety	NN
cord-322904-9mta0aem	267	20	of	of	IN
cord-322904-9mta0aem	267	21	monosaccharides	monosaccharide	NNS
cord-322904-9mta0aem	267	22	via	via	IN
cord-322904-9mta0aem	267	23	different	different	JJ
cord-322904-9mta0aem	267	24	glycosidic	glycosidic	JJ
cord-322904-9mta0aem	267	25	linkages	linkage	NNS
cord-322904-9mta0aem	267	26	.	.	.
cord-322904-9mta0aem	268	1	Physiological	physiological	JJ
cord-322904-9mta0aem	268	2	functions	function	NNS
cord-322904-9mta0aem	268	3	include	include	VBP
cord-322904-9mta0aem	268	4	cell	cell	NN
cord-322904-9mta0aem	268	5	-	-	HYPH
cord-322904-9mta0aem	268	6	cell	cell	NN
cord-322904-9mta0aem	268	7	attachment	attachment	NN
cord-322904-9mta0aem	268	8	via	via	IN
cord-322904-9mta0aem	268	9	specific	specific	JJ
cord-322904-9mta0aem	268	10	receptors	receptor	NNS
cord-322904-9mta0aem	268	11	,	,	,
cord-322904-9mta0aem	268	12	general	general	JJ
cord-322904-9mta0aem	268	13	charge	charge	NN
cord-322904-9mta0aem	268	14	repulsion	repulsion	NN
cord-322904-9mta0aem	268	15	of	of	IN
cord-322904-9mta0aem	268	16	blood	blood	NN
cord-322904-9mta0aem	268	17	cells	cell	NNS
cord-322904-9mta0aem	268	18	as	as	RB
cord-322904-9mta0aem	268	19	well	well	RB
cord-322904-9mta0aem	268	20	as	as	IN
cord-322904-9mta0aem	268	21	roles	role	NNS
cord-322904-9mta0aem	268	22	in	in	IN
cord-322904-9mta0aem	268	23	neuronal	neuronal	JJ
cord-322904-9mta0aem	268	24	plasticity	plasticity	NN
cord-322904-9mta0aem	268	25	,	,	,
cord-322904-9mta0aem	268	26	immune	immune	JJ
cord-322904-9mta0aem	268	27	regulation	regulation	NN
cord-322904-9mta0aem	268	28	and	and	CC
cord-322904-9mta0aem	268	29	glomerular	glomerular	JJ
cord-322904-9mta0aem	268	30	filtration	filtration	NN
cord-322904-9mta0aem	268	31	(	(	-LRB-
cord-322904-9mta0aem	268	32	reviewed	review	VBN
cord-322904-9mta0aem	268	33	in	in	IN
cord-322904-9mta0aem	268	34	(	(	-LRB-
cord-322904-9mta0aem	268	35	Varki	Varki	NNP
cord-322904-9mta0aem	268	36	,	,	,
cord-322904-9mta0aem	268	37	2008	2008	CD
cord-322904-9mta0aem	268	38	)	)	-RRB-
cord-322904-9mta0aem	268	39	.	.	.
cord-322904-9mta0aem	269	1	Many	many	JJ
cord-322904-9mta0aem	269	2	pathogens	pathogen	NNS
cord-322904-9mta0aem	269	3	attach	attach	VBP
cord-322904-9mta0aem	269	4	to	to	IN
cord-322904-9mta0aem	269	5	sialic	sialic	JJ
cord-322904-9mta0aem	269	6	acid	acid	NN
cord-322904-9mta0aem	269	7	-	-	HYPH
cord-322904-9mta0aem	269	8	containing	contain	VBG
cord-322904-9mta0aem	269	9	receptors	receptor	NNS
cord-322904-9mta0aem	269	10	to	to	TO
cord-322904-9mta0aem	269	11	enter	enter	VB
cord-322904-9mta0aem	269	12	cells	cell	NNS
cord-322904-9mta0aem	269	13	,	,	,
cord-322904-9mta0aem	269	14	such	such	JJ
cord-322904-9mta0aem	269	15	as	as	IN
cord-322904-9mta0aem	269	16	a	a	DT
cord-322904-9mta0aem	269	17	number	number	NN
cord-322904-9mta0aem	269	18	of	of	IN
cord-322904-9mta0aem	269	19	viruses	virus	NNS
cord-322904-9mta0aem	269	20	as	as	RB
cord-322904-9mta0aem	269	21	well	well	RB
cord-322904-9mta0aem	269	22	as	as	IN
cord-322904-9mta0aem	269	23	bacterial	bacterial	JJ
cord-322904-9mta0aem	269	24	toxins	toxin	NNS
cord-322904-9mta0aem	269	25	belonging	belong	VBG
cord-322904-9mta0aem	269	26	to	to	IN
cord-322904-9mta0aem	269	27	the	the	DT
cord-322904-9mta0aem	269	28	Clostridium	clostridium	NN
cord-322904-9mta0aem	269	29	neurotoxin	neurotoxin	NN
cord-322904-9mta0aem	269	30	and	and	CC
cord-322904-9mta0aem	269	31	AB	AB	NNP
cord-322904-9mta0aem	269	32	5	5	CD
cord-322904-9mta0aem	269	33	families	family	NNS
cord-322904-9mta0aem	269	34	.	.	.
cord-322904-9mta0aem	270	1	The	the	DT
cord-322904-9mta0aem	270	2	most	most	RBS
cord-322904-9mta0aem	270	3	common	common	JJ
cord-322904-9mta0aem	270	4	sialic	sialic	NN
cord-322904-9mta0aem	270	5	acid	acid	NN
cord-322904-9mta0aem	270	6	in	in	IN
cord-322904-9mta0aem	270	7	humans	human	NNS
cord-322904-9mta0aem	270	8	is	be	VBZ
cord-322904-9mta0aem	270	9	N	n	CD
cord-322904-9mta0aem	270	10	-	-	HYPH
cord-322904-9mta0aem	270	11	acetyl	acetyl	NN
cord-322904-9mta0aem	270	12	neuraminic	neuraminic	JJ
cord-322904-9mta0aem	270	13	acid	acid	NN
cord-322904-9mta0aem	270	14	(	(	-LRB-
cord-322904-9mta0aem	270	15	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	270	16	)	)	-RRB-
cord-322904-9mta0aem	270	17	.	.	.
cord-322904-9mta0aem	271	1	It	-PRON-	PRP
cord-322904-9mta0aem	271	2	forms	form	VBZ
cord-322904-9mta0aem	271	3	a	a	DT
cord-322904-9mta0aem	271	4	six	six	CD
cord-322904-9mta0aem	271	5	-	-	HYPH
cord-322904-9mta0aem	271	6	membered	membered	JJ
cord-322904-9mta0aem	271	7	glycosidic	glycosidic	JJ
cord-322904-9mta0aem	271	8	ring	ring	NN
cord-322904-9mta0aem	271	9	,	,	,
cord-322904-9mta0aem	271	10	to	to	IN
cord-322904-9mta0aem	271	11	which	which	WDT
cord-322904-9mta0aem	271	12	several	several	JJ
cord-322904-9mta0aem	271	13	groups	group	NNS
cord-322904-9mta0aem	271	14	are	be	VBP
cord-322904-9mta0aem	271	15	attached	attach	VBN
cord-322904-9mta0aem	271	16	,	,	,
cord-322904-9mta0aem	271	17	some	some	DT
cord-322904-9mta0aem	271	18	in	in	IN
cord-322904-9mta0aem	271	19	substitution	substitution	NN
cord-322904-9mta0aem	271	20	for	for	IN
cord-322904-9mta0aem	271	21	the	the	DT
cord-322904-9mta0aem	271	22	typical	typical	JJ
cord-322904-9mta0aem	271	23	hydroxyl	hydroxyl	NN
cord-322904-9mta0aem	271	24	groups	group	NNS
cord-322904-9mta0aem	271	25	of	of	IN
cord-322904-9mta0aem	271	26	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	271	27	:	:	:
cord-322904-9mta0aem	271	28	a	a	DT
cord-322904-9mta0aem	271	29	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	271	30	group	group	NN
cord-322904-9mta0aem	271	31	at	at	IN
cord-322904-9mta0aem	271	32	the	the	DT
cord-322904-9mta0aem	271	33	anomeric	anomeric	NN
cord-322904-9mta0aem	271	34	carbon	carbon	NN
cord-322904-9mta0aem	271	35	C2	C2	NNP
cord-322904-9mta0aem	271	36	,	,	,
cord-322904-9mta0aem	271	37	an	an	DT
cord-322904-9mta0aem	271	38	N	n	CD
cord-322904-9mta0aem	271	39	-	-	HYPH
cord-322904-9mta0aem	271	40	acetyl	acetyl	NN
cord-322904-9mta0aem	271	41	group	group	NN
cord-322904-9mta0aem	271	42	at	at	IN
cord-322904-9mta0aem	271	43	the	the	DT
cord-322904-9mta0aem	271	44	C5	C5	NNP
cord-322904-9mta0aem	271	45	carbon	carbon	NN
cord-322904-9mta0aem	271	46	,	,	,
cord-322904-9mta0aem	271	47	and	and	CC
cord-322904-9mta0aem	271	48	a	a	DT
cord-322904-9mta0aem	271	49	glycerol	glycerol	NN
cord-322904-9mta0aem	271	50	chain	chain	NN
cord-322904-9mta0aem	271	51	at	at	IN
cord-322904-9mta0aem	271	52	carbon	carbon	NN
cord-322904-9mta0aem	271	53	C6	c6	NN
cord-322904-9mta0aem	271	54	(	(	-LRB-
cord-322904-9mta0aem	271	55	Fig	Fig	NNP
cord-322904-9mta0aem	271	56	.	.	.
cord-322904-9mta0aem	271	57	4A	4a	CD
cord-322904-9mta0aem	271	58	)	)	-RRB-
cord-322904-9mta0aem	271	59	.	.	.
cord-322904-9mta0aem	272	1	The	the	DT
cord-322904-9mta0aem	272	2	overall	overall	JJ
cord-322904-9mta0aem	272	3	structure	structure	NN
cord-322904-9mta0aem	272	4	of	of	IN
cord-322904-9mta0aem	272	5	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	272	6	is	be	VBZ
cord-322904-9mta0aem	272	7	rather	rather	RB
cord-322904-9mta0aem	272	8	rigid	rigid	JJ
cord-322904-9mta0aem	272	9	.	.	.
cord-322904-9mta0aem	273	1	In	in	IN
cord-322904-9mta0aem	273	2	solution	solution	NN
cord-322904-9mta0aem	273	3	,	,	,
cord-322904-9mta0aem	273	4	the	the	DT
cord-322904-9mta0aem	273	5	sugar	sugar	NN
cord-322904-9mta0aem	273	6	ring	ring	NN
cord-322904-9mta0aem	273	7	prefers	prefer	VBZ
cord-322904-9mta0aem	273	8	the	the	DT
cord-322904-9mta0aem	273	9	energetically	energetically	RB
cord-322904-9mta0aem	273	10	most	most	RBS
cord-322904-9mta0aem	273	11	favorable	favorable	JJ
cord-322904-9mta0aem	273	12	chair	chair	NN
cord-322904-9mta0aem	273	13	conformation	conformation	NN
cord-322904-9mta0aem	273	14	,	,	,
cord-322904-9mta0aem	273	15	positioning	position	VBG
cord-322904-9mta0aem	273	16	its	-PRON-	PRP$
cord-322904-9mta0aem	273	17	three	three	CD
cord-322904-9mta0aem	273	18	distinctive	distinctive	JJ
cord-322904-9mta0aem	273	19	groups	group	NNS
cord-322904-9mta0aem	273	20	in	in	IN
cord-322904-9mta0aem	273	21	three	three	CD
cord-322904-9mta0aem	273	22	different	different	JJ
cord-322904-9mta0aem	273	23	directions	direction	NNS
cord-322904-9mta0aem	273	24	that	that	WDT
cord-322904-9mta0aem	273	25	serve	serve	VBP
cord-322904-9mta0aem	273	26	as	as	IN
cord-322904-9mta0aem	273	27	"	"	``
cord-322904-9mta0aem	273	28	handles	handle	NNS
cord-322904-9mta0aem	273	29	"	"	''
cord-322904-9mta0aem	273	30	with	with	IN
cord-322904-9mta0aem	273	31	which	which	WDT
cord-322904-9mta0aem	273	32	attachment	attachment	NN
cord-322904-9mta0aem	273	33	proteins	protein	NNS
cord-322904-9mta0aem	273	34	can	can	MD
cord-322904-9mta0aem	273	35	interact	interact	VB
cord-322904-9mta0aem	273	36	.	.	.
cord-322904-9mta0aem	274	1	While	while	IN
cord-322904-9mta0aem	274	2	the	the	DT
cord-322904-9mta0aem	274	3	glycerol	glycerol	NN
cord-322904-9mta0aem	274	4	chain	chain	NN
cord-322904-9mta0aem	274	5	with	with	IN
cord-322904-9mta0aem	274	6	three	three	CD
cord-322904-9mta0aem	274	7	freely	freely	RB
cord-322904-9mta0aem	274	8	rotating	rotate	VBG
cord-322904-9mta0aem	274	9	bonds	bond	NNS
cord-322904-9mta0aem	274	10	is	be	VBZ
cord-322904-9mta0aem	274	11	quite	quite	RB
cord-322904-9mta0aem	274	12	flexible	flexible	JJ
cord-322904-9mta0aem	274	13	,	,	,
cord-322904-9mta0aem	274	14	the	the	DT
cord-322904-9mta0aem	274	15	other	other	JJ
cord-322904-9mta0aem	274	16	two	two	CD
cord-322904-9mta0aem	274	17	groups	group	NNS
cord-322904-9mta0aem	274	18	possess	possess	VBP
cord-322904-9mta0aem	274	19	limited	limited	JJ
cord-322904-9mta0aem	274	20	degrees	degree	NNS
cord-322904-9mta0aem	274	21	of	of	IN
cord-322904-9mta0aem	274	22	rotational	rotational	JJ
cord-322904-9mta0aem	274	23	freedom	freedom	NN
cord-322904-9mta0aem	274	24	.	.	.
cord-322904-9mta0aem	275	1	High	high	JJ
cord-322904-9mta0aem	275	2	-	-	HYPH
cord-322904-9mta0aem	275	3	resolution	resolution	NN
cord-322904-9mta0aem	275	4	structural	structural	JJ
cord-322904-9mta0aem	275	5	information	information	NN
cord-322904-9mta0aem	275	6	on	on	IN
cord-322904-9mta0aem	275	7	the	the	DT
cord-322904-9mta0aem	275	8	interaction	interaction	NN
cord-322904-9mta0aem	275	9	of	of	IN
cord-322904-9mta0aem	275	10	viral	viral	JJ
cord-322904-9mta0aem	275	11	attachment	attachment	NN
cord-322904-9mta0aem	275	12	proteins	protein	NNS
cord-322904-9mta0aem	275	13	with	with	IN
cord-322904-9mta0aem	275	14	sialylated	sialylated	JJ
cord-322904-9mta0aem	275	15	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	275	16	is	be	VBZ
cord-322904-9mta0aem	275	17	available	available	JJ
cord-322904-9mta0aem	275	18	for	for	IN
cord-322904-9mta0aem	275	19	the	the	DT
cord-322904-9mta0aem	275	20	following	follow	VBG
cord-322904-9mta0aem	275	21	systems	system	NNS
cord-322904-9mta0aem	275	22	:	:	:
cord-322904-9mta0aem	275	23	Influenza	influenza	NN
cord-322904-9mta0aem	275	24	virus	virus	NN
cord-322904-9mta0aem	275	25	A	a	DT
cord-322904-9mta0aem	275	26	haemagglutinin	haemagglutinin	NN
cord-322904-9mta0aem	275	27	(	(	-LRB-
cord-322904-9mta0aem	275	28	HA	HA	NNP
cord-322904-9mta0aem	275	29	)	)	-RRB-
cord-322904-9mta0aem	275	30	in	in	IN
cord-322904-9mta0aem	275	31	complex	complex	NN
cord-322904-9mta0aem	275	32	with	with	IN
cord-322904-9mta0aem	275	33	oligosaccharides	oligosaccharide	NNS
cord-322904-9mta0aem	275	34	containing	contain	VBG
cord-322904-9mta0aem	275	35	α2,3-linked	α2,3-linked	CD
cord-322904-9mta0aem	275	36	and	and	CC
cord-322904-9mta0aem	275	37	α2,6linked	α2,6linke	VBD
cord-322904-9mta0aem	275	38	NeuNAc	neunac	XX
cord-322904-9mta0aem	276	1	(	(	-LRB-
cord-322904-9mta0aem	276	2	Eisen	Eisen	NNP
cord-322904-9mta0aem	276	3	et	et	NNP
cord-322904-9mta0aem	276	4	al	al	NNP
cord-322904-9mta0aem	276	5	.	.	NNP
cord-322904-9mta0aem	276	6	,	,	,
cord-322904-9mta0aem	276	7	1997	1997	CD
cord-322904-9mta0aem	276	8	;	;	:
cord-322904-9mta0aem	276	9	Gamblin	Gamblin	NNP
cord-322904-9mta0aem	276	10	et	et	FW
cord-322904-9mta0aem	276	11	al	al	NNP
cord-322904-9mta0aem	276	12	.	.	NNP
cord-322904-9mta0aem	276	13	,	,	,
cord-322904-9mta0aem	276	14	2004	2004	CD
cord-322904-9mta0aem	276	15	;	;	:
cord-322904-9mta0aem	277	1	Ha	ha	UH
cord-322904-9mta0aem	277	2	et	et	FW
cord-322904-9mta0aem	277	3	al	al	NNP
cord-322904-9mta0aem	277	4	.	.	NNP
cord-322904-9mta0aem	277	5	,	,	,
cord-322904-9mta0aem	277	6	2001	2001	CD
cord-322904-9mta0aem	277	7	;	;	:
cord-322904-9mta0aem	277	8	Ha	ha	UH
cord-322904-9mta0aem	277	9	et	et	FW
cord-322904-9mta0aem	277	10	al	al	NNP
cord-322904-9mta0aem	277	11	.	.	NNP
cord-322904-9mta0aem	277	12	,	,	,
cord-322904-9mta0aem	277	13	2003	2003	CD
cord-322904-9mta0aem	278	1	;	;	:
cord-322904-9mta0aem	278	2	Russell	Russell	NNP
cord-322904-9mta0aem	278	3	et	et	NNP
cord-322904-9mta0aem	278	4	al	al	NNP
cord-322904-9mta0aem	278	5	.	.	NNP
cord-322904-9mta0aem	278	6	,	,	,
cord-322904-9mta0aem	278	7	2006	2006	CD
cord-322904-9mta0aem	278	8	;	;	:
cord-322904-9mta0aem	278	9	Sauter	Sauter	NNP
cord-322904-9mta0aem	278	10	et	et	FW
cord-322904-9mta0aem	278	11	al	al	NNP
cord-322904-9mta0aem	278	12	.	.	.
cord-322904-9mta0aem	279	1	,	,	,
cord-322904-9mta0aem	279	2	1992	1992	CD
cord-322904-9mta0aem	279	3	;	;	:
cord-322904-9mta0aem	279	4	Stevens	Stevens	NNP
cord-322904-9mta0aem	279	5	et	et	NNP
cord-322904-9mta0aem	279	6	al	al	NNP
cord-322904-9mta0aem	279	7	.	.	NNP
cord-322904-9mta0aem	279	8	,	,	,
cord-322904-9mta0aem	279	9	2006	2006	CD
cord-322904-9mta0aem	279	10	;	;	.
cord-322904-9mta0aem	280	1	Stevens	Stevens	NNP
cord-322904-9mta0aem	280	2	et	et	NNP
cord-322904-9mta0aem	280	3	al	al	NNP
cord-322904-9mta0aem	280	4	.	.	NNP
cord-322904-9mta0aem	280	5	,	,	,
cord-322904-9mta0aem	280	6	2004	2004	CD
cord-322904-9mta0aem	281	1	;	;	:
cord-322904-9mta0aem	281	2	Weis	Weis	NNP
cord-322904-9mta0aem	281	3	et	et	NNP
cord-322904-9mta0aem	281	4	al	al	NNP
cord-322904-9mta0aem	281	5	.	.	NNP
cord-322904-9mta0aem	281	6	,	,	,
cord-322904-9mta0aem	281	7	1988	1988	CD
cord-322904-9mta0aem	281	8	)	)	-RRB-
cord-322904-9mta0aem	281	9	,	,	,
cord-322904-9mta0aem	281	10	mPyV	mpyv	JJ
cord-322904-9mta0aem	281	11	VP1	vp1	NN
cord-322904-9mta0aem	281	12	with	with	IN
cord-322904-9mta0aem	281	13	a	a	DT
cord-322904-9mta0aem	281	14	fragment	fragment	NN
cord-322904-9mta0aem	281	15	of	of	IN
cord-322904-9mta0aem	281	16	ganglioside	ganglioside	NN
cord-322904-9mta0aem	281	17	GD1a	GD1a	NNP
cord-322904-9mta0aem	281	18	(	(	-LRB-
cord-322904-9mta0aem	281	19	Stehle	Stehle	NNP
cord-322904-9mta0aem	281	20	and	and	CC
cord-322904-9mta0aem	281	21	Harrison	Harrison	NNP
cord-322904-9mta0aem	281	22	,	,	,
cord-322904-9mta0aem	281	23	1997	1997	CD
cord-322904-9mta0aem	281	24	)	)	-RRB-
cord-322904-9mta0aem	281	25	,	,	,
cord-322904-9mta0aem	281	26	rhesus	rhesu	NNS
cord-322904-9mta0aem	281	27	,	,	,
cord-322904-9mta0aem	281	28	swine	swine	NN
cord-322904-9mta0aem	281	29	and	and	CC
cord-322904-9mta0aem	281	30	human	human	JJ
cord-322904-9mta0aem	281	31	rotavirus	rotavirus	NN
cord-322904-9mta0aem	281	32	VP8⁎	vp8⁎	NN
cord-322904-9mta0aem	281	33	with	with	IN
cord-322904-9mta0aem	281	34	methyl	methyl	NN
cord-322904-9mta0aem	281	35	-	-	HYPH
cord-322904-9mta0aem	281	36	α2,3-sialoside	α2,3-sialoside	NN
cord-322904-9mta0aem	281	37	(	(	-LRB-
cord-322904-9mta0aem	282	1	Blanchard	Blanchard	NNP
cord-322904-9mta0aem	282	2	et	et	NNP
cord-322904-9mta0aem	282	3	al	al	NNP
cord-322904-9mta0aem	282	4	.	.	.
cord-322904-9mta0aem	283	1	,	,	,
cord-322904-9mta0aem	283	2	2007	2007	CD
cord-322904-9mta0aem	283	3	;	;	:
cord-322904-9mta0aem	283	4	Dormitzer	Dormitzer	NNP
cord-322904-9mta0aem	283	5	et	et	FW
cord-322904-9mta0aem	283	6	al	al	NNP
cord-322904-9mta0aem	283	7	.	.	NNP
cord-322904-9mta0aem	283	8	,	,	,
cord-322904-9mta0aem	283	9	2002a	2002a	CD
cord-322904-9mta0aem	283	10	)	)	-RRB-
cord-322904-9mta0aem	283	11	,	,	,
cord-322904-9mta0aem	283	12	adenovirus	adenovirus	NN
cord-322904-9mta0aem	283	13	Ad37	Ad37	NNP
cord-322904-9mta0aem	284	1	fiber	fiber	NN
cord-322904-9mta0aem	284	2	knob	knob	NN
cord-322904-9mta0aem	284	3	(	(	-LRB-
cord-322904-9mta0aem	284	4	Ad37	Ad37	NNP
cord-322904-9mta0aem	284	5	)	)	-RRB-
cord-322904-9mta0aem	284	6	with	with	IN
cord-322904-9mta0aem	284	7	α2,3and	α2,3and	NNP
cord-322904-9mta0aem	284	8	α2,6-sialyllactose	α2,6-sialyllactose	.
cord-322904-9mta0aem	284	9	(	(	-LRB-
cord-322904-9mta0aem	284	10	Burmeister	Burmeister	NNP
cord-322904-9mta0aem	284	11	et	et	NNP
cord-322904-9mta0aem	284	12	al	al	NNP
cord-322904-9mta0aem	284	13	.	.	NNP
cord-322904-9mta0aem	284	14	,	,	,
cord-322904-9mta0aem	284	15	2004	2004	CD
cord-322904-9mta0aem	284	16	)	)	-RRB-
cord-322904-9mta0aem	284	17	and	and	CC
cord-322904-9mta0aem	284	18	SV40	SV40	NNP
cord-322904-9mta0aem	284	19	VP1	VP1	NNP
cord-322904-9mta0aem	284	20	with	with	IN
cord-322904-9mta0aem	284	21	ganglioside	ganglioside	NN
cord-322904-9mta0aem	285	1	GM1	GM1	NNP
cord-322904-9mta0aem	285	2	(	(	-LRB-
cord-322904-9mta0aem	285	3	Neu	Neu	NNP
cord-322904-9mta0aem	285	4	et	et	FW
cord-322904-9mta0aem	285	5	al	al	NNP
cord-322904-9mta0aem	285	6	.	.	NNP
cord-322904-9mta0aem	285	7	,	,	,
cord-322904-9mta0aem	285	8	2008	2008	CD
cord-322904-9mta0aem	285	9	)	)	-RRB-
cord-322904-9mta0aem	285	10	.	.	.
cord-322904-9mta0aem	286	1	Paramyxoviruses	paramyxovirus	NNS
cord-322904-9mta0aem	286	2	bind	bind	VBP
cord-322904-9mta0aem	286	3	to	to	IN
cord-322904-9mta0aem	286	4	their	-PRON-	PRP$
cord-322904-9mta0aem	286	5	host	host	NN
cord-322904-9mta0aem	286	6	cells	cell	NNS
cord-322904-9mta0aem	286	7	with	with	IN
cord-322904-9mta0aem	286	8	their	-PRON-	PRP$
cord-322904-9mta0aem	286	9	haemagglutininneuraminidase	haemagglutininneuraminidase	NN
cord-322904-9mta0aem	286	10	protein	protein	NN
cord-322904-9mta0aem	286	11	that	that	WDT
cord-322904-9mta0aem	286	12	uses	use	VBZ
cord-322904-9mta0aem	286	13	the	the	DT
cord-322904-9mta0aem	286	14	same	same	JJ
cord-322904-9mta0aem	286	15	binding	binding	NN
cord-322904-9mta0aem	286	16	site	site	NN
cord-322904-9mta0aem	286	17	for	for	IN
cord-322904-9mta0aem	286	18	attachment	attachment	NN
cord-322904-9mta0aem	286	19	to	to	IN
cord-322904-9mta0aem	286	20	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	286	21	and	and	CC
cord-322904-9mta0aem	286	22	cleavage	cleavage	NN
cord-322904-9mta0aem	286	23	of	of	IN
cord-322904-9mta0aem	286	24	its	-PRON-	PRP$
cord-322904-9mta0aem	286	25	glycosidic	glycosidic	JJ
cord-322904-9mta0aem	286	26	bond	bond	NN
cord-322904-9mta0aem	286	27	(	(	-LRB-
cord-322904-9mta0aem	286	28	Crennell	Crennell	NNP
cord-322904-9mta0aem	286	29	et	et	NNP
cord-322904-9mta0aem	286	30	al	al	NNP
cord-322904-9mta0aem	286	31	.	.	NNP
cord-322904-9mta0aem	286	32	,	,	,
cord-322904-9mta0aem	286	33	2000	2000	CD
cord-322904-9mta0aem	286	34	)	)	-RRB-
cord-322904-9mta0aem	286	35	.	.	.
cord-322904-9mta0aem	287	1	We	-PRON-	PRP
cord-322904-9mta0aem	287	2	will	will	MD
cord-322904-9mta0aem	287	3	,	,	,
cord-322904-9mta0aem	287	4	however	however	RB
cord-322904-9mta0aem	287	5	,	,	,
cord-322904-9mta0aem	287	6	focus	focus	VBP
cord-322904-9mta0aem	287	7	here	here	RB
cord-322904-9mta0aem	287	8	on	on	IN
cord-322904-9mta0aem	287	9	viral	viral	JJ
cord-322904-9mta0aem	287	10	proteins	protein	NNS
cord-322904-9mta0aem	287	11	that	that	WDT
cord-322904-9mta0aem	287	12	solely	solely	RB
cord-322904-9mta0aem	287	13	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	287	14	is	be	VBZ
cord-322904-9mta0aem	287	15	depicted	depict	VBN
cord-322904-9mta0aem	287	16	in	in	IN
cord-322904-9mta0aem	287	17	orange	orange	NNP
cord-322904-9mta0aem	287	18	,	,	,
cord-322904-9mta0aem	287	19	the	the	DT
cord-322904-9mta0aem	287	20	protein	protein	NN
cord-322904-9mta0aem	287	21	residues	residue	NNS
cord-322904-9mta0aem	287	22	forming	form	VBG
cord-322904-9mta0aem	287	23	hydrogen	hydrogen	NN
cord-322904-9mta0aem	287	24	bonds	bond	NNS
cord-322904-9mta0aem	287	25	to	to	IN
cord-322904-9mta0aem	287	26	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	287	27	are	be	VBP
cord-322904-9mta0aem	287	28	colored	color	VBN
cord-322904-9mta0aem	287	29	green	green	JJ
cord-322904-9mta0aem	287	30	and	and	CC
cord-322904-9mta0aem	287	31	the	the	DT
cord-322904-9mta0aem	287	32	residues	residue	NNS
cord-322904-9mta0aem	287	33	making	make	VBG
cord-322904-9mta0aem	287	34	van	van	NNP
cord-322904-9mta0aem	287	35	der	der	NNP
cord-322904-9mta0aem	287	36	Waals	Waals	NNP
cord-322904-9mta0aem	287	37	contacts	contact	NNS
cord-322904-9mta0aem	287	38	are	be	VBP
cord-322904-9mta0aem	287	39	colored	color	VBN
cord-322904-9mta0aem	287	40	grey	grey	NN
cord-322904-9mta0aem	287	41	.	.	.
cord-322904-9mta0aem	288	1	The	the	DT
cord-322904-9mta0aem	288	2	viral	viral	JJ
cord-322904-9mta0aem	288	3	surface	surface	NN
cord-322904-9mta0aem	288	4	is	be	VBZ
cord-322904-9mta0aem	288	5	shown	show	VBN
cord-322904-9mta0aem	288	6	in	in	IN
cord-322904-9mta0aem	288	7	grey	grey	NN
cord-322904-9mta0aem	288	8	.	.	.
cord-322904-9mta0aem	289	1	This	this	DT
cord-322904-9mta0aem	289	2	figure	figure	NN
cord-322904-9mta0aem	289	3	was	be	VBD
cord-322904-9mta0aem	289	4	prepared	prepare	VBN
cord-322904-9mta0aem	289	5	with	with	IN
cord-322904-9mta0aem	289	6	PyMol	PyMol	NNP
cord-322904-9mta0aem	290	1	(	(	-LRB-
cord-322904-9mta0aem	290	2	DeLano	DeLano	NNP
cord-322904-9mta0aem	290	3	Scientific	Scientific	NNP
cord-322904-9mta0aem	290	4	,	,	,
cord-322904-9mta0aem	290	5	Inc.	Inc.	NNP
cord-322904-9mta0aem	290	6	)	)	-RRB-
cord-322904-9mta0aem	290	7	.	.	.
cord-322904-9mta0aem	291	1	mediate	mediate	VB
cord-322904-9mta0aem	291	2	attachment	attachment	NN
cord-322904-9mta0aem	291	3	and	and	CC
cord-322904-9mta0aem	291	4	do	do	VBP
cord-322904-9mta0aem	291	5	not	not	RB
cord-322904-9mta0aem	291	6	possess	possess	VB
cord-322904-9mta0aem	291	7	enzymatic	enzymatic	JJ
cord-322904-9mta0aem	291	8	activity	activity	NN
cord-322904-9mta0aem	291	9	.	.	.
cord-322904-9mta0aem	292	1	Sialic	sialic	NN
cord-322904-9mta0aem	292	2	acid	acid	NN
cord-322904-9mta0aem	292	3	binding	bind	VBG
cord-322904-9mta0aem	292	4	by	by	IN
cord-322904-9mta0aem	292	5	catalytically	catalytically	RB
cord-322904-9mta0aem	292	6	active	active	JJ
cord-322904-9mta0aem	292	7	viral	viral	JJ
cord-322904-9mta0aem	292	8	neuraminidases	neuraminidase	NNS
cord-322904-9mta0aem	292	9	is	be	VBZ
cord-322904-9mta0aem	292	10	probably	probably	RB
cord-322904-9mta0aem	292	11	not	not	RB
cord-322904-9mta0aem	292	12	directly	directly	RB
cord-322904-9mta0aem	292	13	comparable	comparable	JJ
cord-322904-9mta0aem	292	14	to	to	IN
cord-322904-9mta0aem	292	15	binding	bind	VBG
cord-322904-9mta0aem	292	16	by	by	IN
cord-322904-9mta0aem	292	17	attachment	attachment	NN
cord-322904-9mta0aem	292	18	proteins	protein	NNS
cord-322904-9mta0aem	292	19	,	,	,
cord-322904-9mta0aem	292	20	as	as	IN
cord-322904-9mta0aem	292	21	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	292	22	function	function	NN
cord-322904-9mta0aem	292	23	requires	require	VBZ
cord-322904-9mta0aem	292	24	high	high	JJ
cord-322904-9mta0aem	292	25	affinity	affinity	NN
cord-322904-9mta0aem	292	26	as	as	RB
cord-322904-9mta0aem	292	27	well	well	RB
cord-322904-9mta0aem	292	28	as	as	IN
cord-322904-9mta0aem	292	29	additional	additional	JJ
cord-322904-9mta0aem	292	30	binding	bind	VBG
cord-322904-9mta0aem	292	31	energy	energy	NN
cord-322904-9mta0aem	292	32	to	to	TO
cord-322904-9mta0aem	292	33	distort	distort	VB
cord-322904-9mta0aem	292	34	the	the	DT
cord-322904-9mta0aem	292	35	sialic	sialic	JJ
cord-322904-9mta0aem	292	36	acid	acid	NN
cord-322904-9mta0aem	292	37	for	for	IN
cord-322904-9mta0aem	292	38	catalysis	catalysis	NN
cord-322904-9mta0aem	292	39	.	.	.
cord-322904-9mta0aem	293	1	Neuraminidases	Neuraminidases	NNP
cord-322904-9mta0aem	293	2	thus	thus	RB
cord-322904-9mta0aem	293	3	feature	feature	VBP
cord-322904-9mta0aem	293	4	deeply	deeply	RB
cord-322904-9mta0aem	293	5	buried	bury	VBN
cord-322904-9mta0aem	293	6	binding	bind	VBG
cord-322904-9mta0aem	293	7	sites	site	NNS
cord-322904-9mta0aem	293	8	with	with	IN
cord-322904-9mta0aem	293	9	a	a	DT
cord-322904-9mta0aem	293	10	higher	high	JJR
cord-322904-9mta0aem	293	11	number	number	NN
cord-322904-9mta0aem	293	12	of	of	IN
cord-322904-9mta0aem	293	13	specific	specific	JJ
cord-322904-9mta0aem	293	14	contacts	contact	NNS
cord-322904-9mta0aem	293	15	than	than	IN
cord-322904-9mta0aem	293	16	are	be	VBP
cord-322904-9mta0aem	293	17	found	find	VBN
cord-322904-9mta0aem	293	18	in	in	IN
cord-322904-9mta0aem	293	19	attachment	attachment	NN
cord-322904-9mta0aem	293	20	proteins	protein	NNS
cord-322904-9mta0aem	293	21	.	.	.
cord-322904-9mta0aem	294	1	Although	although	IN
cord-322904-9mta0aem	294	2	most	most	JJS
cord-322904-9mta0aem	294	3	of	of	IN
cord-322904-9mta0aem	294	4	the	the	DT
cord-322904-9mta0aem	294	5	attachment	attachment	NN
cord-322904-9mta0aem	294	6	proteins	protein	NNS
cord-322904-9mta0aem	294	7	listed	list	VBN
cord-322904-9mta0aem	294	8	above	above	RB
cord-322904-9mta0aem	294	9	are	be	VBP
cord-322904-9mta0aem	294	10	not	not	RB
cord-322904-9mta0aem	294	11	homologous	homologous	JJ
cord-322904-9mta0aem	294	12	and	and	CC
cord-322904-9mta0aem	294	13	are	be	VBP
cord-322904-9mta0aem	294	14	found	find	VBN
cord-322904-9mta0aem	294	15	on	on	IN
cord-322904-9mta0aem	294	16	unrelated	unrelated	JJ
cord-322904-9mta0aem	294	17	enveloped	envelop	VBN
cord-322904-9mta0aem	294	18	as	as	RB
cord-322904-9mta0aem	294	19	well	well	RB
cord-322904-9mta0aem	294	20	as	as	IN
cord-322904-9mta0aem	294	21	nonenveloped	nonenveloped	JJ
cord-322904-9mta0aem	294	22	viruses	virus	NNS
cord-322904-9mta0aem	294	23	,	,	,
cord-322904-9mta0aem	294	24	there	there	EX
cord-322904-9mta0aem	294	25	are	be	VBP
cord-322904-9mta0aem	294	26	some	some	DT
cord-322904-9mta0aem	294	27	general	general	JJ
cord-322904-9mta0aem	294	28	similarities	similarity	NNS
cord-322904-9mta0aem	294	29	in	in	IN
cord-322904-9mta0aem	294	30	the	the	DT
cord-322904-9mta0aem	294	31	modes	mode	NNS
cord-322904-9mta0aem	294	32	of	of	IN
cord-322904-9mta0aem	294	33	oligosaccharide	oligosaccharide	NN
cord-322904-9mta0aem	294	34	binding	binding	NN
cord-322904-9mta0aem	294	35	.	.	.
cord-322904-9mta0aem	295	1	First	first	RB
cord-322904-9mta0aem	295	2	,	,	,
cord-322904-9mta0aem	295	3	in	in	IN
cord-322904-9mta0aem	295	4	all	all	DT
cord-322904-9mta0aem	295	5	viral	viral	JJ
cord-322904-9mta0aem	295	6	complexes	complex	NNS
cord-322904-9mta0aem	295	7	,	,	,
cord-322904-9mta0aem	295	8	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	295	9	is	be	VBZ
cord-322904-9mta0aem	295	10	the	the	DT
cord-322904-9mta0aem	295	11	major	major	JJ
cord-322904-9mta0aem	295	12	,	,	,
cord-322904-9mta0aem	295	13	and	and	CC
cord-322904-9mta0aem	295	14	in	in	IN
cord-322904-9mta0aem	295	15	the	the	DT
cord-322904-9mta0aem	295	16	case	case	NN
cord-322904-9mta0aem	295	17	of	of	IN
cord-322904-9mta0aem	295	18	Ad37	Ad37	NNP
cord-322904-9mta0aem	295	19	and	and	CC
cord-322904-9mta0aem	295	20	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	295	21	the	the	DT
cord-322904-9mta0aem	295	22	only	only	JJ
cord-322904-9mta0aem	295	23	,	,	,
cord-322904-9mta0aem	295	24	point	point	NN
cord-322904-9mta0aem	295	25	of	of	IN
cord-322904-9mta0aem	295	26	contact	contact	NN
cord-322904-9mta0aem	295	27	.	.	.
cord-322904-9mta0aem	296	1	This	this	DT
cord-322904-9mta0aem	296	2	distinguishes	distinguish	VBZ
cord-322904-9mta0aem	296	3	these	these	DT
cord-322904-9mta0aem	296	4	complexes	complex	NNS
cord-322904-9mta0aem	296	5	from	from	IN
cord-322904-9mta0aem	296	6	,	,	,
cord-322904-9mta0aem	296	7	for	for	IN
cord-322904-9mta0aem	296	8	example	example	NN
cord-322904-9mta0aem	296	9	,	,	,
cord-322904-9mta0aem	296	10	bacterial	bacterial	JJ
cord-322904-9mta0aem	296	11	toxins	toxin	NNS
cord-322904-9mta0aem	296	12	,	,	,
cord-322904-9mta0aem	296	13	which	which	WDT
cord-322904-9mta0aem	296	14	can	can	MD
cord-322904-9mta0aem	296	15	also	also	RB
cord-322904-9mta0aem	296	16	recognize	recognize	VB
cord-322904-9mta0aem	296	17	sialylated	sialylated	JJ
cord-322904-9mta0aem	296	18	receptors	receptor	NNS
cord-322904-9mta0aem	296	19	but	but	CC
cord-322904-9mta0aem	296	20	form	form	VB
cord-322904-9mta0aem	296	21	more	more	JJR
cord-322904-9mta0aem	296	22	contacts	contact	NNS
cord-322904-9mta0aem	296	23	with	with	IN
cord-322904-9mta0aem	296	24	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	296	25	attached	attach	VBN
cord-322904-9mta0aem	296	26	to	to	IN
cord-322904-9mta0aem	296	27	sialic	sialic	JJ
cord-322904-9mta0aem	296	28	acid	acid	NN
cord-322904-9mta0aem	296	29	than	than	IN
cord-322904-9mta0aem	296	30	with	with	IN
cord-322904-9mta0aem	296	31	the	the	DT
cord-322904-9mta0aem	296	32	sialic	sialic	JJ
cord-322904-9mta0aem	296	33	acid	acid	NN
cord-322904-9mta0aem	296	34	itself	-PRON-	PRP
cord-322904-9mta0aem	297	1	(	(	-LRB-
cord-322904-9mta0aem	297	2	Fotinou	Fotinou	NNP
cord-322904-9mta0aem	297	3	et	et	NNP
cord-322904-9mta0aem	297	4	al	al	NNP
cord-322904-9mta0aem	297	5	.	.	NNP
cord-322904-9mta0aem	297	6	,	,	,
cord-322904-9mta0aem	297	7	2001	2001	CD
cord-322904-9mta0aem	298	1	;	;	:
cord-322904-9mta0aem	298	2	Merritt	Merritt	NNP
cord-322904-9mta0aem	298	3	et	et	NNP
cord-322904-9mta0aem	298	4	al	al	NNP
cord-322904-9mta0aem	298	5	.	.	NNP
cord-322904-9mta0aem	298	6	,	,	,
cord-322904-9mta0aem	298	7	1994	1994	CD
cord-322904-9mta0aem	298	8	;	;	:
cord-322904-9mta0aem	298	9	Stenmark	Stenmark	NNP
cord-322904-9mta0aem	298	10	et	et	FW
cord-322904-9mta0aem	298	11	al	al	NNP
cord-322904-9mta0aem	298	12	.	.	NNP
cord-322904-9mta0aem	298	13	,	,	,
cord-322904-9mta0aem	298	14	2008	2008	CD
cord-322904-9mta0aem	298	15	)	)	-RRB-
cord-322904-9mta0aem	298	16	.	.	.
cord-322904-9mta0aem	299	1	Second	second	RB
cord-322904-9mta0aem	299	2	,	,	,
cord-322904-9mta0aem	299	3	all	all	DT
cord-322904-9mta0aem	299	4	viral	viral	JJ
cord-322904-9mta0aem	299	5	attachment	attachment	NN
cord-322904-9mta0aem	299	6	complexes	complex	NNS
cord-322904-9mta0aem	299	7	bind	bind	VBP
cord-322904-9mta0aem	299	8	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	299	9	in	in	IN
cord-322904-9mta0aem	299	10	shallow	shallow	JJ
cord-322904-9mta0aem	299	11	depressions	depression	NNS
cord-322904-9mta0aem	299	12	rather	rather	RB
cord-322904-9mta0aem	299	13	than	than	IN
cord-322904-9mta0aem	299	14	deep	deep	JJ
cord-322904-9mta0aem	299	15	grooves	groove	NNS
cord-322904-9mta0aem	299	16	on	on	IN
cord-322904-9mta0aem	299	17	the	the	DT
cord-322904-9mta0aem	299	18	protein	protein	NN
cord-322904-9mta0aem	299	19	surface	surface	NN
cord-322904-9mta0aem	299	20	.	.	.
cord-322904-9mta0aem	300	1	The	the	DT
cord-322904-9mta0aem	300	2	affinities	affinity	NNS
cord-322904-9mta0aem	300	3	for	for	IN
cord-322904-9mta0aem	300	4	these	these	DT
cord-322904-9mta0aem	300	5	interactions	interaction	NNS
cord-322904-9mta0aem	300	6	are	be	VBP
cord-322904-9mta0aem	300	7	only	only	RB
cord-322904-9mta0aem	300	8	in	in	IN
cord-322904-9mta0aem	300	9	the	the	DT
cord-322904-9mta0aem	300	10	millimolar	millimolar	JJ
cord-322904-9mta0aem	300	11	range	range	NN
cord-322904-9mta0aem	300	12	,	,	,
cord-322904-9mta0aem	300	13	which	which	WDT
cord-322904-9mta0aem	300	14	is	be	VBZ
cord-322904-9mta0aem	300	15	consistent	consistent	JJ
cord-322904-9mta0aem	300	16	with	with	IN
cord-322904-9mta0aem	300	17	the	the	DT
cord-322904-9mta0aem	300	18	exposed	expose	VBN
cord-322904-9mta0aem	300	19	binding	binding	NN
cord-322904-9mta0aem	300	20	surfaces	surface	NNS
cord-322904-9mta0aem	300	21	(	(	-LRB-
cord-322904-9mta0aem	300	22	Burmeister	Burmeister	NNP
cord-322904-9mta0aem	300	23	et	et	NNP
cord-322904-9mta0aem	300	24	al	al	NNP
cord-322904-9mta0aem	300	25	.	.	NNP
cord-322904-9mta0aem	300	26	,	,	,
cord-322904-9mta0aem	300	27	2004	2004	CD
cord-322904-9mta0aem	300	28	;	;	:
cord-322904-9mta0aem	300	29	Dormitzer	Dormitzer	NNP
cord-322904-9mta0aem	300	30	et	et	FW
cord-322904-9mta0aem	300	31	al	al	NNP
cord-322904-9mta0aem	300	32	.	.	.
cord-322904-9mta0aem	301	1	,	,	,
cord-322904-9mta0aem	301	2	2002b	2002b	CD
cord-322904-9mta0aem	301	3	;	;	:
cord-322904-9mta0aem	301	4	Eisen	Eisen	NNP
cord-322904-9mta0aem	301	5	et	et	NNP
cord-322904-9mta0aem	301	6	al	al	NNP
cord-322904-9mta0aem	301	7	.	.	NNP
cord-322904-9mta0aem	301	8	,	,	,
cord-322904-9mta0aem	301	9	1997	1997	CD
cord-322904-9mta0aem	301	10	;	;	:
cord-322904-9mta0aem	301	11	Neu	Neu	NNP
cord-322904-9mta0aem	301	12	et	et	FW
cord-322904-9mta0aem	301	13	al	al	NNP
cord-322904-9mta0aem	301	14	.	.	.
cord-322904-9mta0aem	302	1	,	,	,
cord-322904-9mta0aem	302	2	2008	2008	CD
cord-322904-9mta0aem	302	3	;	;	:
cord-322904-9mta0aem	302	4	Stehle	Stehle	NNP
cord-322904-9mta0aem	302	5	et	et	FW
cord-322904-9mta0aem	302	6	al	al	NNP
cord-322904-9mta0aem	302	7	.	.	NNP
cord-322904-9mta0aem	302	8	,	,	,
cord-322904-9mta0aem	302	9	1996	1996	CD
cord-322904-9mta0aem	302	10	)	)	-RRB-
cord-322904-9mta0aem	302	11	.	.	.
cord-322904-9mta0aem	303	1	A	a	DT
cord-322904-9mta0aem	303	2	relatively	relatively	RB
cord-322904-9mta0aem	303	3	low	low	JJ
cord-322904-9mta0aem	303	4	affinity	affinity	NN
cord-322904-9mta0aem	303	5	may	may	MD
cord-322904-9mta0aem	303	6	in	in	IN
cord-322904-9mta0aem	303	7	fact	fact	NN
cord-322904-9mta0aem	303	8	be	be	VB
cord-322904-9mta0aem	303	9	crucial	crucial	JJ
cord-322904-9mta0aem	303	10	for	for	IN
cord-322904-9mta0aem	303	11	a	a	DT
cord-322904-9mta0aem	303	12	productive	productive	JJ
cord-322904-9mta0aem	303	13	viral	viral	JJ
cord-322904-9mta0aem	303	14	infection	infection	NN
cord-322904-9mta0aem	303	15	as	as	IN
cord-322904-9mta0aem	303	16	a	a	DT
cord-322904-9mta0aem	303	17	very	very	RB
cord-322904-9mta0aem	303	18	tight	tight	JJ
cord-322904-9mta0aem	303	19	attachment	attachment	NN
cord-322904-9mta0aem	303	20	to	to	IN
cord-322904-9mta0aem	303	21	the	the	DT
cord-322904-9mta0aem	303	22	host	host	NN
cord-322904-9mta0aem	303	23	cell	cell	NN
cord-322904-9mta0aem	303	24	will	will	MD
cord-322904-9mta0aem	303	25	prevent	prevent	VB
cord-322904-9mta0aem	303	26	progeny	progeny	JJ
cord-322904-9mta0aem	303	27	virus	virus	NN
cord-322904-9mta0aem	303	28	from	from	IN
cord-322904-9mta0aem	303	29	spreading	spread	VBG
cord-322904-9mta0aem	303	30	.	.	.
cord-322904-9mta0aem	304	1	Third	third	RB
cord-322904-9mta0aem	304	2	,	,	,
cord-322904-9mta0aem	304	3	the	the	DT
cord-322904-9mta0aem	304	4	attachment	attachment	NN
cord-322904-9mta0aem	304	5	protein	protein	NN
cord-322904-9mta0aem	304	6	complexes	complex	NNS
cord-322904-9mta0aem	304	7	all	all	DT
cord-322904-9mta0aem	304	8	feature	feature	VBP
cord-322904-9mta0aem	304	9	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	304	10	in	in	IN
cord-322904-9mta0aem	304	11	its	-PRON-	PRP$
cord-322904-9mta0aem	304	12	chair	chair	NN
cord-322904-9mta0aem	304	13	conformation	conformation	NN
cord-322904-9mta0aem	304	14	,	,	,
cord-322904-9mta0aem	304	15	which	which	WDT
cord-322904-9mta0aem	304	16	is	be	VBZ
cord-322904-9mta0aem	304	17	the	the	DT
cord-322904-9mta0aem	304	18	preferred	preferred	JJ
cord-322904-9mta0aem	304	19	conformation	conformation	NN
cord-322904-9mta0aem	304	20	in	in	IN
cord-322904-9mta0aem	304	21	solution	solution	NN
cord-322904-9mta0aem	304	22	.	.	.
cord-322904-9mta0aem	305	1	Fourth	fourth	RB
cord-322904-9mta0aem	305	2	,	,	,
cord-322904-9mta0aem	305	3	as	as	IN
cord-322904-9mta0aem	305	4	detailed	detail	VBN
cord-322904-9mta0aem	305	5	in	in	IN
cord-322904-9mta0aem	305	6	the	the	DT
cord-322904-9mta0aem	305	7	next	next	JJ
cord-322904-9mta0aem	305	8	section	section	NN
cord-322904-9mta0aem	305	9	,	,	,
cord-322904-9mta0aem	305	10	there	there	EX
cord-322904-9mta0aem	305	11	are	be	VBP
cord-322904-9mta0aem	305	12	several	several	JJ
cord-322904-9mta0aem	305	13	parallels	parallel	NNS
cord-322904-9mta0aem	305	14	in	in	IN
cord-322904-9mta0aem	305	15	the	the	DT
cord-322904-9mta0aem	305	16	strategies	strategy	NNS
cord-322904-9mta0aem	305	17	used	use	VBN
cord-322904-9mta0aem	305	18	by	by	IN
cord-322904-9mta0aem	305	19	attachment	attachment	NN
cord-322904-9mta0aem	305	20	proteins	protein	NNS
cord-322904-9mta0aem	305	21	to	to	TO
cord-322904-9mta0aem	305	22	bind	bind	VB
cord-322904-9mta0aem	305	23	sialic	sialic	NN
cord-322904-9mta0aem	305	24	acid	acid	NN
cord-322904-9mta0aem	305	25	.	.	.
cord-322904-9mta0aem	306	1	The	the	DT
cord-322904-9mta0aem	306	2	listed	list	VBN
cord-322904-9mta0aem	306	3	similarities	similarity	NNS
cord-322904-9mta0aem	306	4	observed	observe	VBN
cord-322904-9mta0aem	306	5	in	in	IN
cord-322904-9mta0aem	306	6	complexes	complex	NNS
cord-322904-9mta0aem	306	7	of	of	IN
cord-322904-9mta0aem	306	8	viral	viral	JJ
cord-322904-9mta0aem	306	9	attachment	attachment	NN
cord-322904-9mta0aem	306	10	proteins	protein	NNS
cord-322904-9mta0aem	306	11	and	and	CC
cord-322904-9mta0aem	306	12	sialylated	sialylated	JJ
cord-322904-9mta0aem	306	13	receptors	receptor	NNS
cord-322904-9mta0aem	306	14	do	do	VBP
cord-322904-9mta0aem	306	15	not	not	RB
cord-322904-9mta0aem	306	16	extend	extend	VB
cord-322904-9mta0aem	306	17	to	to	IN
cord-322904-9mta0aem	306	18	other	other	JJ
cord-322904-9mta0aem	306	19	proteins	protein	NNS
cord-322904-9mta0aem	306	20	that	that	WDT
cord-322904-9mta0aem	306	21	also	also	RB
cord-322904-9mta0aem	306	22	bind	bind	VBP
cord-322904-9mta0aem	306	23	the	the	DT
cord-322904-9mta0aem	306	24	same	same	JJ
cord-322904-9mta0aem	306	25	type	type	NN
cord-322904-9mta0aem	306	26	of	of	IN
cord-322904-9mta0aem	306	27	receptors	receptor	NNS
cord-322904-9mta0aem	306	28	,	,	,
cord-322904-9mta0aem	306	29	indicating	indicate	VBG
cord-322904-9mta0aem	306	30	that	that	IN
cord-322904-9mta0aem	306	31	they	-PRON-	PRP
cord-322904-9mta0aem	306	32	do	do	VBP
cord-322904-9mta0aem	306	33	represent	represent	VB
cord-322904-9mta0aem	306	34	characteristic	characteristic	JJ
cord-322904-9mta0aem	306	35	properties	property	NNS
cord-322904-9mta0aem	306	36	of	of	IN
cord-322904-9mta0aem	306	37	viral	viral	JJ
cord-322904-9mta0aem	306	38	proteins	protein	NNS
cord-322904-9mta0aem	306	39	that	that	WDT
cord-322904-9mta0aem	306	40	mediate	mediate	VBP
cord-322904-9mta0aem	306	41	engagement	engagement	NN
cord-322904-9mta0aem	306	42	of	of	IN
cord-322904-9mta0aem	306	43	host	host	NN
cord-322904-9mta0aem	306	44	cell	cell	NN
cord-322904-9mta0aem	306	45	receptors	receptor	NNS
cord-322904-9mta0aem	306	46	.	.	.
cord-322904-9mta0aem	307	1	For	for	IN
cord-322904-9mta0aem	307	2	example	example	NN
cord-322904-9mta0aem	307	3	,	,	,
cord-322904-9mta0aem	307	4	the	the	DT
cord-322904-9mta0aem	307	5	low	low	JJ
cord-322904-9mta0aem	307	6	affinity	affinity	NN
cord-322904-9mta0aem	307	7	binding	bind	VBG
cord-322904-9mta0aem	307	8	by	by	IN
cord-322904-9mta0aem	307	9	viral	viral	JJ
cord-322904-9mta0aem	307	10	attachment	attachment	NN
cord-322904-9mta0aem	307	11	proteins	protein	NNS
cord-322904-9mta0aem	307	12	is	be	VBZ
cord-322904-9mta0aem	307	13	in	in	IN
cord-322904-9mta0aem	307	14	contrast	contrast	NN
cord-322904-9mta0aem	307	15	to	to	IN
cord-322904-9mta0aem	307	16	bacterial	bacterial	JJ
cord-322904-9mta0aem	307	17	toxins	toxin	NNS
cord-322904-9mta0aem	307	18	,	,	,
cord-322904-9mta0aem	307	19	which	which	WDT
cord-322904-9mta0aem	307	20	also	also	RB
cord-322904-9mta0aem	307	21	bind	bind	VBP
cord-322904-9mta0aem	307	22	sialylated	sialylated	JJ
cord-322904-9mta0aem	307	23	oligosaccharides	oligosaccharide	NNS
cord-322904-9mta0aem	307	24	but	but	CC
cord-322904-9mta0aem	307	25	employ	employ	VB
cord-322904-9mta0aem	307	26	deeper	deep	JJR
cord-322904-9mta0aem	307	27	pockets	pocket	NNS
cord-322904-9mta0aem	307	28	and	and	CC
cord-322904-9mta0aem	307	29	generally	generally	RB
cord-322904-9mta0aem	307	30	feature	feature	VBP
cord-322904-9mta0aem	307	31	significantly	significantly	RB
cord-322904-9mta0aem	307	32	higher	high	JJR
cord-322904-9mta0aem	307	33	affinity	affinity	NN
cord-322904-9mta0aem	307	34	(	(	-LRB-
cord-322904-9mta0aem	307	35	Fotinou	Fotinou	NNP
cord-322904-9mta0aem	307	36	et	et	NNP
cord-322904-9mta0aem	307	37	al	al	NNP
cord-322904-9mta0aem	307	38	.	.	NNP
cord-322904-9mta0aem	307	39	,	,	,
cord-322904-9mta0aem	307	40	2001	2001	CD
cord-322904-9mta0aem	307	41	;	;	:
cord-322904-9mta0aem	307	42	Merritt	Merritt	NNP
cord-322904-9mta0aem	307	43	et	et	NNP
cord-322904-9mta0aem	307	44	al	al	NNP
cord-322904-9mta0aem	307	45	.	.	NNP
cord-322904-9mta0aem	307	46	,	,	,
cord-322904-9mta0aem	307	47	1994	1994	CD
cord-322904-9mta0aem	307	48	;	;	:
cord-322904-9mta0aem	307	49	Stenmark	Stenmark	NNP
cord-322904-9mta0aem	307	50	et	et	FW
cord-322904-9mta0aem	307	51	al	al	NNP
cord-322904-9mta0aem	307	52	.	.	NNP
cord-322904-9mta0aem	307	53	,	,	,
cord-322904-9mta0aem	307	54	2008	2008	CD
cord-322904-9mta0aem	307	55	)	)	-RRB-
cord-322904-9mta0aem	307	56	.	.	.
cord-322904-9mta0aem	308	1	In	in	IN
cord-322904-9mta0aem	308	2	contrast	contrast	NN
cord-322904-9mta0aem	308	3	to	to	IN
cord-322904-9mta0aem	308	4	the	the	DT
cord-322904-9mta0aem	308	5	numerous	numerous	JJ
cord-322904-9mta0aem	308	6	binding	bind	VBG
cord-322904-9mta0aem	308	7	sites	site	NNS
cord-322904-9mta0aem	308	8	on	on	IN
cord-322904-9mta0aem	308	9	viruses	virus	NNS
cord-322904-9mta0aem	308	10	,	,	,
cord-322904-9mta0aem	308	11	bacterial	bacterial	JJ
cord-322904-9mta0aem	308	12	toxins	toxin	NNS
cord-322904-9mta0aem	308	13	have	have	VBP
cord-322904-9mta0aem	308	14	only	only	RB
cord-322904-9mta0aem	308	15	one	one	CD
cord-322904-9mta0aem	308	16	or	or	CC
cord-322904-9mta0aem	308	17	at	at	IN
cord-322904-9mta0aem	308	18	most	most	RBS
cord-322904-9mta0aem	308	19	five	five	CD
cord-322904-9mta0aem	308	20	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	308	21	binding	bind	VBG
cord-322904-9mta0aem	308	22	sites	site	NNS
cord-322904-9mta0aem	308	23	,	,	,
cord-322904-9mta0aem	308	24	and	and	CC
cord-322904-9mta0aem	308	25	the	the	DT
cord-322904-9mta0aem	308	26	interactions	interaction	NNS
cord-322904-9mta0aem	308	27	between	between	IN
cord-322904-9mta0aem	308	28	these	these	DT
cord-322904-9mta0aem	308	29	and	and	CC
cord-322904-9mta0aem	308	30	cellular	cellular	JJ
cord-322904-9mta0aem	308	31	receptors	receptor	NNS
cord-322904-9mta0aem	308	32	must	must	MD
cord-322904-9mta0aem	308	33	be	be	VB
cord-322904-9mta0aem	308	34	sufficient	sufficient	JJ
cord-322904-9mta0aem	308	35	to	to	TO
cord-322904-9mta0aem	308	36	provide	provide	VB
cord-322904-9mta0aem	308	37	cell	cell	NN
cord-322904-9mta0aem	308	38	entry	entry	NN
cord-322904-9mta0aem	308	39	.	.	.
cord-322904-9mta0aem	309	1	The	the	DT
cord-322904-9mta0aem	309	2	charged	charge	VBN
cord-322904-9mta0aem	309	3	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	309	4	group	group	NN
cord-322904-9mta0aem	309	5	of	of	IN
cord-322904-9mta0aem	309	6	sialic	sialic	JJ
cord-322904-9mta0aem	309	7	acid	acid	NN
cord-322904-9mta0aem	309	8	is	be	VBZ
cord-322904-9mta0aem	309	9	arguably	arguably	RB
cord-322904-9mta0aem	309	10	the	the	DT
cord-322904-9mta0aem	309	11	most	most	RBS
cord-322904-9mta0aem	309	12	uniquely	uniquely	RB
cord-322904-9mta0aem	309	13	identifiable	identifiable	JJ
cord-322904-9mta0aem	309	14	feature	feature	NN
cord-322904-9mta0aem	309	15	of	of	IN
cord-322904-9mta0aem	309	16	this	this	DT
cord-322904-9mta0aem	309	17	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	309	18	when	when	WRB
cord-322904-9mta0aem	309	19	compared	compare	VBN
cord-322904-9mta0aem	309	20	to	to	IN
cord-322904-9mta0aem	309	21	similar	similar	JJ
cord-322904-9mta0aem	309	22	,	,	,
cord-322904-9mta0aem	309	23	uncharged	uncharged	JJ
cord-322904-9mta0aem	309	24	structures	structure	NNS
cord-322904-9mta0aem	309	25	.	.	.
cord-322904-9mta0aem	310	1	It	-PRON-	PRP
cord-322904-9mta0aem	310	2	is	be	VBZ
cord-322904-9mta0aem	310	3	therefore	therefore	RB
cord-322904-9mta0aem	310	4	perhaps	perhaps	RB
cord-322904-9mta0aem	310	5	not	not	RB
cord-322904-9mta0aem	310	6	surprising	surprising	JJ
cord-322904-9mta0aem	310	7	that	that	IN
cord-322904-9mta0aem	310	8	all	all	DT
cord-322904-9mta0aem	310	9	of	of	IN
cord-322904-9mta0aem	310	10	the	the	DT
cord-322904-9mta0aem	310	11	viruses	virus	NNS
cord-322904-9mta0aem	310	12	or	or	CC
cord-322904-9mta0aem	310	13	viral	viral	JJ
cord-322904-9mta0aem	310	14	proteins	protein	NNS
cord-322904-9mta0aem	310	15	investigated	investigate	VBN
cord-322904-9mta0aem	310	16	here	here	RB
cord-322904-9mta0aem	310	17	engage	engage	VBP
cord-322904-9mta0aem	310	18	this	this	DT
cord-322904-9mta0aem	310	19	group	group	NN
cord-322904-9mta0aem	310	20	.	.	.
cord-322904-9mta0aem	311	1	However	however	RB
cord-322904-9mta0aem	311	2	,	,	,
cord-322904-9mta0aem	311	3	they	-PRON-	PRP
cord-322904-9mta0aem	311	4	do	do	VBP
cord-322904-9mta0aem	311	5	so	so	RB
cord-322904-9mta0aem	311	6	by	by	IN
cord-322904-9mta0aem	311	7	employing	employ	VBG
cord-322904-9mta0aem	311	8	two	two	CD
cord-322904-9mta0aem	311	9	different	different	JJ
cord-322904-9mta0aem	311	10	strategies	strategy	NNS
cord-322904-9mta0aem	311	11	.	.	.
cord-322904-9mta0aem	312	1	The	the	DT
cord-322904-9mta0aem	312	2	mPyV	mPyV	NNP
cord-322904-9mta0aem	312	3	and	and	CC
cord-322904-9mta0aem	312	4	Ad37	Ad37	NNP
cord-322904-9mta0aem	312	5	form	form	NN
cord-322904-9mta0aem	312	6	salt	salt	NN
cord-322904-9mta0aem	312	7	bridges	bridge	NNS
cord-322904-9mta0aem	312	8	from	from	IN
cord-322904-9mta0aem	312	9	the	the	DT
cord-322904-9mta0aem	312	10	positively	positively	RB
cord-322904-9mta0aem	312	11	charged	charge	VBN
cord-322904-9mta0aem	312	12	side	side	NN
cord-322904-9mta0aem	312	13	chains	chain	NNS
cord-322904-9mta0aem	312	14	of	of	IN
cord-322904-9mta0aem	312	15	Arg	Arg	NNP
cord-322904-9mta0aem	312	16	and	and	CC
cord-322904-9mta0aem	312	17	Lys	Lys	NNP
cord-322904-9mta0aem	312	18	residues	residue	NNS
cord-322904-9mta0aem	312	19	to	to	IN
cord-322904-9mta0aem	312	20	the	the	DT
cord-322904-9mta0aem	312	21	negatively	negatively	RB
cord-322904-9mta0aem	312	22	charged	charge	VBN
cord-322904-9mta0aem	312	23	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	312	24	group	group	NN
cord-322904-9mta0aem	312	25	(	(	-LRB-
cord-322904-9mta0aem	312	26	Figs	Figs	NNP
cord-322904-9mta0aem	312	27	.	.	.
cord-322904-9mta0aem	312	28	4E	4E	NNP
cord-322904-9mta0aem	312	29	and	and	CC
cord-322904-9mta0aem	312	30	C	C	NNP
cord-322904-9mta0aem	312	31	,	,	,
cord-322904-9mta0aem	312	32	respectively	respectively	RB
cord-322904-9mta0aem	312	33	)	)	-RRB-
cord-322904-9mta0aem	312	34	.	.	.
cord-322904-9mta0aem	313	1	By	by	IN
cord-322904-9mta0aem	313	2	contrast	contrast	NN
cord-322904-9mta0aem	313	3	,	,	,
cord-322904-9mta0aem	313	4	the	the	DT
cord-322904-9mta0aem	313	5	other	other	JJ
cord-322904-9mta0aem	313	6	three	three	CD
cord-322904-9mta0aem	313	7	viruses	virus	NNS
cord-322904-9mta0aem	313	8	engage	engage	VBP
cord-322904-9mta0aem	313	9	the	the	DT
cord-322904-9mta0aem	313	10	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	313	11	group	group	NN
cord-322904-9mta0aem	313	12	with	with	IN
cord-322904-9mta0aem	313	13	two	two	CD
cord-322904-9mta0aem	313	14	parallel	parallel	JJ
cord-322904-9mta0aem	313	15	hydrogen	hydrogen	NN
cord-322904-9mta0aem	313	16	bonds	bond	NNS
cord-322904-9mta0aem	313	17	.	.	.
cord-322904-9mta0aem	314	1	In	in	IN
cord-322904-9mta0aem	314	2	each	each	DT
cord-322904-9mta0aem	314	3	case	case	NN
cord-322904-9mta0aem	314	4	,	,	,
cord-322904-9mta0aem	314	5	the	the	DT
cord-322904-9mta0aem	314	6	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	314	7	group	group	NN
cord-322904-9mta0aem	314	8	accepts	accept	VBZ
cord-322904-9mta0aem	314	9	two	two	CD
cord-322904-9mta0aem	314	10	hydrogen	hydrogen	NN
cord-322904-9mta0aem	314	11	bonds	bond	NNS
cord-322904-9mta0aem	314	12	from	from	IN
cord-322904-9mta0aem	314	13	two	two	CD
cord-322904-9mta0aem	314	14	specifically	specifically	RB
cord-322904-9mta0aem	314	15	spaced	space	VBN
cord-322904-9mta0aem	314	16	hydrogen	hydrogen	NN
cord-322904-9mta0aem	314	17	bond	bond	NN
cord-322904-9mta0aem	314	18	donors	donor	NNS
cord-322904-9mta0aem	314	19	in	in	IN
cord-322904-9mta0aem	314	20	the	the	DT
cord-322904-9mta0aem	314	21	proteins	protein	NNS
cord-322904-9mta0aem	314	22	.	.	.
cord-322904-9mta0aem	315	1	In	in	IN
cord-322904-9mta0aem	315	2	the	the	DT
cord-322904-9mta0aem	315	3	Influenza	Influenza	NNP
cord-322904-9mta0aem	315	4	HA	HA	NNP
cord-322904-9mta0aem	315	5	,	,	,
cord-322904-9mta0aem	315	6	SV40	SV40	NNP
cord-322904-9mta0aem	315	7	VP1	VP1	NNP
cord-322904-9mta0aem	315	8	and	and	CC
cord-322904-9mta0aem	315	9	Rotavirus	Rotavirus	NNP
cord-322904-9mta0aem	315	10	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	315	11	complexes	complex	NNS
cord-322904-9mta0aem	315	12	,	,	,
cord-322904-9mta0aem	315	13	these	these	DT
cord-322904-9mta0aem	315	14	are	be	VBP
cord-322904-9mta0aem	315	15	either	either	CC
cord-322904-9mta0aem	315	16	the	the	DT
cord-322904-9mta0aem	315	17	hydroxyl	hydroxyl	NN
cord-322904-9mta0aem	315	18	groups	group	NNS
cord-322904-9mta0aem	315	19	of	of	IN
cord-322904-9mta0aem	315	20	Ser	Ser	NNP
cord-322904-9mta0aem	315	21	and	and	CC
cord-322904-9mta0aem	315	22	Thr	Thr	NNP
cord-322904-9mta0aem	315	23	side	side	NN
cord-322904-9mta0aem	315	24	chains	chain	NNS
cord-322904-9mta0aem	315	25	or	or	CC
cord-322904-9mta0aem	315	26	backbone	backbone	NN
cord-322904-9mta0aem	315	27	amido	amido	NN
cord-322904-9mta0aem	315	28	groups	group	NNS
cord-322904-9mta0aem	315	29	(	(	-LRB-
cord-322904-9mta0aem	315	30	Figs	fig	NNS
cord-322904-9mta0aem	315	31	.	.	.
cord-322904-9mta0aem	316	1	4B	4B	NNP
cord-322904-9mta0aem	316	2	,	,	,
cord-322904-9mta0aem	316	3	D	D	NNP
cord-322904-9mta0aem	316	4	,	,	,
cord-322904-9mta0aem	316	5	E	E	NNP
cord-322904-9mta0aem	316	6	)	)	-RRB-
cord-322904-9mta0aem	316	7	.	.	.
cord-322904-9mta0aem	317	1	These	these	DT
cord-322904-9mta0aem	317	2	parallel	parallel	JJ
cord-322904-9mta0aem	317	3	hydrogen	hydrogen	NN
cord-322904-9mta0aem	317	4	bonds	bond	NNS
cord-322904-9mta0aem	317	5	also	also	RB
cord-322904-9mta0aem	317	6	have	have	VBP
cord-322904-9mta0aem	317	7	similar	similar	JJ
cord-322904-9mta0aem	317	8	geometry	geometry	NN
cord-322904-9mta0aem	317	9	.	.	.
cord-322904-9mta0aem	318	1	For	for	IN
cord-322904-9mta0aem	318	2	each	each	DT
cord-322904-9mta0aem	318	3	of	of	IN
cord-322904-9mta0aem	318	4	them	-PRON-	PRP
cord-322904-9mta0aem	318	5	,	,	,
cord-322904-9mta0aem	318	6	the	the	DT
cord-322904-9mta0aem	318	7	angle	angle	NN
cord-322904-9mta0aem	318	8	between	between	IN
cord-322904-9mta0aem	318	9	the	the	DT
cord-322904-9mta0aem	318	10	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	318	11	C1	C1	NNP
cord-322904-9mta0aem	318	12	,	,	,
cord-322904-9mta0aem	318	13	the	the	DT
cord-322904-9mta0aem	318	14	carboxylate	carboxylate	NN
cord-322904-9mta0aem	318	15	O	o	NN
cord-322904-9mta0aem	318	16	that	that	WDT
cord-322904-9mta0aem	318	17	is	be	VBZ
cord-322904-9mta0aem	318	18	engaged	engage	VBN
cord-322904-9mta0aem	318	19	and	and	CC
cord-322904-9mta0aem	318	20	the	the	DT
cord-322904-9mta0aem	318	21	hydrogen	hydrogen	NN
cord-322904-9mta0aem	318	22	bond	bond	NN
cord-322904-9mta0aem	318	23	donor	donor	NN
cord-322904-9mta0aem	318	24	approaches	approach	VBZ
cord-322904-9mta0aem	318	25	120	120	CD
cord-322904-9mta0aem	318	26	°	°	NNS
cord-322904-9mta0aem	318	27	.	.	.
cord-322904-9mta0aem	319	1	Recognition	recognition	NN
cord-322904-9mta0aem	319	2	of	of	IN
cord-322904-9mta0aem	319	3	the	the	DT
cord-322904-9mta0aem	319	4	negatively	negatively	RB
cord-322904-9mta0aem	319	5	charged	charge	VBN
cord-322904-9mta0aem	319	6	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	319	7	group	group	NN
cord-322904-9mta0aem	319	8	of	of	IN
cord-322904-9mta0aem	319	9	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	319	10	alone	alone	RB
cord-322904-9mta0aem	319	11	would	would	MD
cord-322904-9mta0aem	319	12	not	not	RB
cord-322904-9mta0aem	319	13	distinguish	distinguish	VB
cord-322904-9mta0aem	319	14	it	-PRON-	PRP
cord-322904-9mta0aem	319	15	from	from	IN
cord-322904-9mta0aem	319	16	other	other	JJ
cord-322904-9mta0aem	319	17	molecules	molecule	NNS
cord-322904-9mta0aem	319	18	bearing	bear	VBG
cord-322904-9mta0aem	319	19	a	a	DT
cord-322904-9mta0aem	319	20	negative	negative	JJ
cord-322904-9mta0aem	319	21	charge	charge	NN
cord-322904-9mta0aem	319	22	.	.	.
cord-322904-9mta0aem	320	1	The	the	DT
cord-322904-9mta0aem	320	2	N	N	NNP
cord-322904-9mta0aem	320	3	-	-	HYPH
cord-322904-9mta0aem	320	4	acetyl	acetyl	NNP
cord-322904-9mta0aem	320	5	group	group	NN
cord-322904-9mta0aem	320	6	,	,	,
cord-322904-9mta0aem	320	7	situated	situate	VBN
cord-322904-9mta0aem	320	8	on	on	IN
cord-322904-9mta0aem	320	9	the	the	DT
cord-322904-9mta0aem	320	10	opposite	opposite	JJ
cord-322904-9mta0aem	320	11	side	side	NN
cord-322904-9mta0aem	320	12	of	of	IN
cord-322904-9mta0aem	320	13	the	the	DT
cord-322904-9mta0aem	320	14	sugar	sugar	NN
cord-322904-9mta0aem	320	15	ring	ring	NN
cord-322904-9mta0aem	320	16	as	as	IN
cord-322904-9mta0aem	320	17	the	the	DT
cord-322904-9mta0aem	320	18	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	320	19	group	group	NN
cord-322904-9mta0aem	320	20	,	,	,
cord-322904-9mta0aem	320	21	can	can	MD
cord-322904-9mta0aem	320	22	serve	serve	VB
cord-322904-9mta0aem	320	23	as	as	RB
cord-322904-9mta0aem	320	24	additional	additional	JJ
cord-322904-9mta0aem	320	25	"	"	``
cord-322904-9mta0aem	320	26	handle	handle	NN
cord-322904-9mta0aem	320	27	"	"	''
cord-322904-9mta0aem	320	28	on	on	IN
cord-322904-9mta0aem	320	29	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	320	30	and	and	CC
cord-322904-9mta0aem	320	31	it	-PRON-	PRP
cord-322904-9mta0aem	320	32	provides	provide	VBZ
cord-322904-9mta0aem	320	33	specificity	specificity	NN
cord-322904-9mta0aem	320	34	by	by	IN
cord-322904-9mta0aem	320	35	additional	additional	JJ
cord-322904-9mta0aem	320	36	favourable	favourable	JJ
cord-322904-9mta0aem	320	37	contacts	contact	NNS
cord-322904-9mta0aem	320	38	with	with	IN
cord-322904-9mta0aem	320	39	the	the	DT
cord-322904-9mta0aem	320	40	correct	correct	JJ
cord-322904-9mta0aem	320	41	ligand	ligand	NN
cord-322904-9mta0aem	320	42	.	.	.
cord-322904-9mta0aem	321	1	The	the	DT
cord-322904-9mta0aem	321	2	N5	N5	NNP
cord-322904-9mta0aem	321	3	atom	atom	NN
cord-322904-9mta0aem	321	4	of	of	IN
cord-322904-9mta0aem	321	5	the	the	DT
cord-322904-9mta0aem	321	6	N	N	NNP
cord-322904-9mta0aem	321	7	-	-	HYPH
cord-322904-9mta0aem	321	8	acetyl	acetyl	NNP
cord-322904-9mta0aem	321	9	group	group	NN
cord-322904-9mta0aem	321	10	is	be	VBZ
cord-322904-9mta0aem	321	11	contacted	contact	VBN
cord-322904-9mta0aem	321	12	by	by	IN
cord-322904-9mta0aem	321	13	a	a	DT
cord-322904-9mta0aem	321	14	hydrogen	hydrogen	NN
cord-322904-9mta0aem	321	15	bond	bond	NN
cord-322904-9mta0aem	321	16	in	in	IN
cord-322904-9mta0aem	321	17	each	each	DT
cord-322904-9mta0aem	321	18	of	of	IN
cord-322904-9mta0aem	321	19	the	the	DT
cord-322904-9mta0aem	321	20	complexes	complex	NNS
cord-322904-9mta0aem	321	21	.	.	.
cord-322904-9mta0aem	322	1	The	the	DT
cord-322904-9mta0aem	322	2	binding	bind	VBG
cord-322904-9mta0aem	322	3	partners	partner	NNS
cord-322904-9mta0aem	322	4	are	be	VBP
cord-322904-9mta0aem	322	5	hydrogen	hydrogen	NN
cord-322904-9mta0aem	322	6	bond	bond	NN
cord-322904-9mta0aem	322	7	acceptors	acceptor	NNS
cord-322904-9mta0aem	322	8	in	in	IN
cord-322904-9mta0aem	322	9	the	the	DT
cord-322904-9mta0aem	322	10	protein	protein	NN
cord-322904-9mta0aem	322	11	,	,	,
cord-322904-9mta0aem	322	12	such	such	JJ
cord-322904-9mta0aem	322	13	as	as	IN
cord-322904-9mta0aem	322	14	backbone	backbone	NN
cord-322904-9mta0aem	322	15	carbonyl	carbonyl	NN
cord-322904-9mta0aem	322	16	groups	group	NNS
cord-322904-9mta0aem	322	17	(	(	-LRB-
cord-322904-9mta0aem	322	18	Figs	fig	NNS
cord-322904-9mta0aem	322	19	.	.	.
cord-322904-9mta0aem	323	1	4B	4b	LS
cord-322904-9mta0aem	323	2	-	-	HYPH
cord-322904-9mta0aem	323	3	D	D	NNP
cord-322904-9mta0aem	323	4	)	)	-RRB-
cord-322904-9mta0aem	323	5	,	,	,
cord-322904-9mta0aem	323	6	the	the	DT
cord-322904-9mta0aem	323	7	side	side	NN
cord-322904-9mta0aem	323	8	chain	chain	NN
cord-322904-9mta0aem	323	9	carbonyl	carbonyl	NN
cord-322904-9mta0aem	323	10	group	group	NN
cord-322904-9mta0aem	323	11	of	of	IN
cord-322904-9mta0aem	323	12	an	an	DT
cord-322904-9mta0aem	323	13	Asn	Asn	NNP
cord-322904-9mta0aem	323	14	residue	residue	NN
cord-322904-9mta0aem	323	15	(	(	-LRB-
cord-322904-9mta0aem	323	16	Fig	Fig	NNP
cord-322904-9mta0aem	323	17	.	.	.
cord-322904-9mta0aem	323	18	4F	4F	NNP
cord-322904-9mta0aem	323	19	)	)	-RRB-
cord-322904-9mta0aem	323	20	or	or	CC
cord-322904-9mta0aem	323	21	the	the	DT
cord-322904-9mta0aem	323	22	hydroxyl	hydroxyl	NN
cord-322904-9mta0aem	323	23	group	group	NN
cord-322904-9mta0aem	323	24	of	of	IN
cord-322904-9mta0aem	323	25	a	a	DT
cord-322904-9mta0aem	323	26	Tyr	Tyr	NNP
cord-322904-9mta0aem	323	27	side	side	NN
cord-322904-9mta0aem	323	28	chain	chain	NN
cord-322904-9mta0aem	323	29	(	(	-LRB-
cord-322904-9mta0aem	323	30	Fig	Fig	NNP
cord-322904-9mta0aem	323	31	.	.	.
cord-322904-9mta0aem	323	32	4E	4E	NNP
cord-322904-9mta0aem	323	33	)	)	-RRB-
cord-322904-9mta0aem	323	34	.	.	.
cord-322904-9mta0aem	324	1	The	the	DT
cord-322904-9mta0aem	324	2	mPyV	mpyv	JJ
cord-322904-9mta0aem	324	3	VP1	vp1	NN
cord-322904-9mta0aem	324	4	also	also	RB
cord-322904-9mta0aem	324	5	forms	form	VBZ
cord-322904-9mta0aem	324	6	an	an	DT
cord-322904-9mta0aem	324	7	additional	additional	JJ
cord-322904-9mta0aem	324	8	hydrogen	hydrogen	NN
cord-322904-9mta0aem	324	9	bond	bond	NN
cord-322904-9mta0aem	324	10	by	by	IN
cord-322904-9mta0aem	324	11	an	an	DT
cord-322904-9mta0aem	324	12	Asn	Asn	NNP
cord-322904-9mta0aem	324	13	side	side	NN
cord-322904-9mta0aem	324	14	chain	chain	NN
cord-322904-9mta0aem	324	15	,	,	,
cord-322904-9mta0aem	324	16	which	which	WDT
cord-322904-9mta0aem	324	17	contacts	contact	VBZ
cord-322904-9mta0aem	324	18	the	the	DT
cord-322904-9mta0aem	324	19	carbonyl	carbonyl	NN
cord-322904-9mta0aem	324	20	group	group	NN
cord-322904-9mta0aem	324	21	of	of	IN
cord-322904-9mta0aem	324	22	the	the	DT
cord-322904-9mta0aem	324	23	acetyl	acetyl	NN
cord-322904-9mta0aem	324	24	function	function	NN
cord-322904-9mta0aem	324	25	.	.	.
cord-322904-9mta0aem	325	1	With	with	IN
cord-322904-9mta0aem	325	2	the	the	DT
cord-322904-9mta0aem	325	3	sole	sole	JJ
cord-322904-9mta0aem	325	4	exception	exception	NN
cord-322904-9mta0aem	325	5	of	of	IN
cord-322904-9mta0aem	325	6	mPyV	mpyv	JJ
cord-322904-9mta0aem	325	7	VP1	VP1	NNP
cord-322904-9mta0aem	325	8	,	,	,
cord-322904-9mta0aem	325	9	the	the	DT
cord-322904-9mta0aem	325	10	binding	bind	VBG
cord-322904-9mta0aem	325	11	sites	site	NNS
cord-322904-9mta0aem	325	12	of	of	IN
cord-322904-9mta0aem	325	13	all	all	DT
cord-322904-9mta0aem	325	14	proteins	protein	NNS
cord-322904-9mta0aem	325	15	also	also	RB
cord-322904-9mta0aem	325	16	feature	feature	VBP
cord-322904-9mta0aem	325	17	a	a	DT
cord-322904-9mta0aem	325	18	depression	depression	NN
cord-322904-9mta0aem	325	19	into	into	IN
cord-322904-9mta0aem	325	20	which	which	WDT
cord-322904-9mta0aem	325	21	the	the	DT
cord-322904-9mta0aem	325	22	methyl	methyl	NN
cord-322904-9mta0aem	325	23	group	group	NN
cord-322904-9mta0aem	325	24	of	of	IN
cord-322904-9mta0aem	325	25	the	the	DT
cord-322904-9mta0aem	325	26	N	N	NNP
cord-322904-9mta0aem	325	27	-	-	HYPH
cord-322904-9mta0aem	325	28	acetyl	acetyl	NNP
cord-322904-9mta0aem	325	29	moiety	moiety	NN
cord-322904-9mta0aem	325	30	inserts	insert	NNS
cord-322904-9mta0aem	325	31	.	.	.
cord-322904-9mta0aem	326	1	This	this	DT
cord-322904-9mta0aem	326	2	depression	depression	NN
cord-322904-9mta0aem	326	3	is	be	VBZ
cord-322904-9mta0aem	326	4	shallow	shallow	JJ
cord-322904-9mta0aem	326	5	and	and	CC
cord-322904-9mta0aem	326	6	rather	rather	RB
cord-322904-9mta0aem	326	7	hydrophobic	hydrophobic	JJ
cord-322904-9mta0aem	326	8	in	in	IN
cord-322904-9mta0aem	326	9	the	the	DT
cord-322904-9mta0aem	326	10	case	case	NN
cord-322904-9mta0aem	326	11	of	of	IN
cord-322904-9mta0aem	326	12	Ad37	Ad37	NNP
cord-322904-9mta0aem	326	13	,	,	,
cord-322904-9mta0aem	326	14	Influenza	Influenza	NNP
cord-322904-9mta0aem	326	15	HA	HA	NNP
cord-322904-9mta0aem	326	16	and	and	CC
cord-322904-9mta0aem	326	17	Rotavirus	Rotavirus	NNP
cord-322904-9mta0aem	326	18	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	326	19	,	,	,
cord-322904-9mta0aem	326	20	as	as	IN
cord-322904-9mta0aem	326	21	it	-PRON-	PRP
cord-322904-9mta0aem	326	22	is	be	VBZ
cord-322904-9mta0aem	326	23	lined	line	VBN
cord-322904-9mta0aem	326	24	with	with	IN
cord-322904-9mta0aem	326	25	hydrophobic	hydrophobic	JJ
cord-322904-9mta0aem	326	26	side	side	NN
cord-322904-9mta0aem	326	27	chains	chain	NNS
cord-322904-9mta0aem	326	28	(	(	-LRB-
cord-322904-9mta0aem	326	29	Figs	fig	NNS
cord-322904-9mta0aem	326	30	.	.	.
cord-322904-9mta0aem	327	1	4B	4b	LS
cord-322904-9mta0aem	327	2	-	-	HYPH
cord-322904-9mta0aem	327	3	D	D	NNP
cord-322904-9mta0aem	327	4	)	)	-RRB-
cord-322904-9mta0aem	327	5	.	.	.
cord-322904-9mta0aem	328	1	Interestingly	interestingly	RB
cord-322904-9mta0aem	328	2	,	,	,
cord-322904-9mta0aem	328	3	SV40	SV40	NNP
cord-322904-9mta0aem	328	4	VP1	VP1	NNP
cord-322904-9mta0aem	328	5	does	do	VBZ
cord-322904-9mta0aem	328	6	not	not	RB
cord-322904-9mta0aem	328	7	feature	feature	VB
cord-322904-9mta0aem	328	8	such	such	PDT
cord-322904-9mta0aem	328	9	a	a	DT
cord-322904-9mta0aem	328	10	shallow	shallow	JJ
cord-322904-9mta0aem	328	11	depression	depression	NN
cord-322904-9mta0aem	328	12	to	to	TO
cord-322904-9mta0aem	328	13	accommodate	accommodate	VB
cord-322904-9mta0aem	328	14	the	the	DT
cord-322904-9mta0aem	328	15	methyl	methyl	NN
cord-322904-9mta0aem	328	16	group	group	NN
cord-322904-9mta0aem	328	17	.	.	.
cord-322904-9mta0aem	329	1	Rather	rather	RB
cord-322904-9mta0aem	329	2	,	,	,
cord-322904-9mta0aem	329	3	it	-PRON-	PRP
cord-322904-9mta0aem	329	4	has	have	VBZ
cord-322904-9mta0aem	329	5	a	a	DT
cord-322904-9mta0aem	329	6	substantially	substantially	RB
cord-322904-9mta0aem	329	7	deeper	deep	JJR
cord-322904-9mta0aem	329	8	pocket	pocket	NN
cord-322904-9mta0aem	329	9	that	that	WDT
cord-322904-9mta0aem	329	10	is	be	VBZ
cord-322904-9mta0aem	329	11	formed	form	VBN
cord-322904-9mta0aem	329	12	by	by	IN
cord-322904-9mta0aem	329	13	hydrophobic	hydrophobic	JJ
cord-322904-9mta0aem	329	14	residues	residue	NNS
cord-322904-9mta0aem	329	15	such	such	JJ
cord-322904-9mta0aem	329	16	as	as	IN
cord-322904-9mta0aem	329	17	Leu65	Leu65	NNP
cord-322904-9mta0aem	329	18	and	and	CC
cord-322904-9mta0aem	329	19	Phe75	Phe75	NNP
cord-322904-9mta0aem	329	20	and	and	CC
cord-322904-9mta0aem	329	21	lined	line	VBD
cord-322904-9mta0aem	329	22	with	with	IN
cord-322904-9mta0aem	329	23	hydrophilic	hydrophilic	JJ
cord-322904-9mta0aem	329	24	side	side	NN
cord-322904-9mta0aem	329	25	chains	chain	NNS
cord-322904-9mta0aem	329	26	of	of	IN
cord-322904-9mta0aem	329	27	residues	residue	NNS
cord-322904-9mta0aem	329	28	Gln62	Gln62	NNP
cord-322904-9mta0aem	329	29	and	and	CC
cord-322904-9mta0aem	329	30	Gln278	gln278	ADD
cord-322904-9mta0aem	329	31	at	at	IN
cord-322904-9mta0aem	329	32	its	-PRON-	PRP$
cord-322904-9mta0aem	329	33	rim	rim	NN
cord-322904-9mta0aem	329	34	(	(	-LRB-
cord-322904-9mta0aem	329	35	Fig	Fig	NNP
cord-322904-9mta0aem	329	36	.	.	.
cord-322904-9mta0aem	329	37	4F	4F	NNP
cord-322904-9mta0aem	329	38	)	)	-RRB-
cord-322904-9mta0aem	329	39	.	.	.
cord-322904-9mta0aem	330	1	The	the	DT
cord-322904-9mta0aem	330	2	natural	natural	JJ
cord-322904-9mta0aem	330	3	hosts	host	NNS
cord-322904-9mta0aem	330	4	of	of	IN
cord-322904-9mta0aem	330	5	SV40	SV40	NNP
cord-322904-9mta0aem	330	6	are	be	VBP
cord-322904-9mta0aem	330	7	monkeys	monkey	NNS
cord-322904-9mta0aem	330	8	,	,	,
cord-322904-9mta0aem	330	9	in	in	IN
cord-322904-9mta0aem	330	10	which	which	WDT
cord-322904-9mta0aem	330	11	N	N	NNP
cord-322904-9mta0aem	330	12	-	-	HYPH
cord-322904-9mta0aem	330	13	glycolyl	glycolyl	VBN
cord-322904-9mta0aem	330	14	neuraminic	neuraminic	JJ
cord-322904-9mta0aem	330	15	acid	acid	NN
cord-322904-9mta0aem	330	16	(	(	-LRB-
cord-322904-9mta0aem	330	17	NeuNGc	neungc	NN
cord-322904-9mta0aem	330	18	)	)	-RRB-
cord-322904-9mta0aem	330	19	is	be	VBZ
cord-322904-9mta0aem	330	20	the	the	DT
cord-322904-9mta0aem	330	21	predominant	predominant	JJ
cord-322904-9mta0aem	330	22	sialic	sialic	NN
cord-322904-9mta0aem	330	23	acid	acid	NN
cord-322904-9mta0aem	330	24	.	.	.
cord-322904-9mta0aem	331	1	In	in	IN
cord-322904-9mta0aem	331	2	contrast	contrast	NN
cord-322904-9mta0aem	331	3	to	to	IN
cord-322904-9mta0aem	331	4	the	the	DT
cord-322904-9mta0aem	331	5	human	human	JJ
cord-322904-9mta0aem	331	6	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	331	7	,	,	,
cord-322904-9mta0aem	331	8	NeuNGc	NeuNGc	NNP
cord-322904-9mta0aem	331	9	has	have	VBZ
cord-322904-9mta0aem	331	10	an	an	DT
cord-322904-9mta0aem	331	11	additional	additional	JJ
cord-322904-9mta0aem	331	12	hydroxyl	hydroxyl	NN
cord-322904-9mta0aem	331	13	group	group	NN
cord-322904-9mta0aem	331	14	attached	attach	VBN
cord-322904-9mta0aem	331	15	to	to	IN
cord-322904-9mta0aem	331	16	the	the	DT
cord-322904-9mta0aem	331	17	methyl	methyl	NN
cord-322904-9mta0aem	331	18	group	group	NN
cord-322904-9mta0aem	331	19	.	.	.
cord-322904-9mta0aem	332	1	The	the	DT
cord-322904-9mta0aem	332	2	big	big	JJ
cord-322904-9mta0aem	332	3	,	,	,
cord-322904-9mta0aem	332	4	partly	partly	RB
cord-322904-9mta0aem	332	5	hydrophilic	hydrophilic	JJ
cord-322904-9mta0aem	332	6	and	and	CC
cord-322904-9mta0aem	332	7	likely	likely	JJ
cord-322904-9mta0aem	332	8	water	water	NN
cord-322904-9mta0aem	332	9	-	-	HYPH
cord-322904-9mta0aem	332	10	filled	fill	VBN
cord-322904-9mta0aem	332	11	cavity	cavity	NN
cord-322904-9mta0aem	332	12	in	in	IN
cord-322904-9mta0aem	332	13	SV40	SV40	NNP
cord-322904-9mta0aem	332	14	could	could	MD
cord-322904-9mta0aem	332	15	likely	likely	RB
cord-322904-9mta0aem	332	16	accommodate	accommodate	VB
cord-322904-9mta0aem	332	17	the	the	DT
cord-322904-9mta0aem	332	18	more	more	RBR
cord-322904-9mta0aem	332	19	polar	polar	JJ
cord-322904-9mta0aem	332	20	NeuNGc	neungc	NN
cord-322904-9mta0aem	332	21	better	well	JJR
cord-322904-9mta0aem	332	22	than	than	IN
cord-322904-9mta0aem	332	23	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	333	1	(	(	-LRB-
cord-322904-9mta0aem	333	2	Campanero	Campanero	NNP
cord-322904-9mta0aem	333	3	-	-	HYPH
cord-322904-9mta0aem	333	4	Rhodes	Rhodes	NNP
cord-322904-9mta0aem	333	5	et	et	NNP
cord-322904-9mta0aem	333	6	al	al	NNP
cord-322904-9mta0aem	333	7	.	.	NNP
cord-322904-9mta0aem	333	8	,	,	,
cord-322904-9mta0aem	333	9	2007	2007	CD
cord-322904-9mta0aem	333	10	)	)	-RRB-
cord-322904-9mta0aem	333	11	,	,	,
cord-322904-9mta0aem	333	12	which	which	WDT
cord-322904-9mta0aem	333	13	might	may	MD
cord-322904-9mta0aem	333	14	account	account	VB
cord-322904-9mta0aem	333	15	for	for	IN
cord-322904-9mta0aem	333	16	its	-PRON-	PRP$
cord-322904-9mta0aem	333	17	shape	shape	NN
cord-322904-9mta0aem	333	18	.	.	.
cord-322904-9mta0aem	334	1	Even	even	RB
cord-322904-9mta0aem	334	2	though	though	IN
cord-322904-9mta0aem	334	3	contacts	contact	NNS
cord-322904-9mta0aem	334	4	with	with	IN
cord-322904-9mta0aem	334	5	the	the	DT
cord-322904-9mta0aem	334	6	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	334	7	and	and	CC
cord-322904-9mta0aem	334	8	N	N	NNP
cord-322904-9mta0aem	334	9	-	-	HYPH
cord-322904-9mta0aem	334	10	acetyl	acetyl	NN
cord-322904-9mta0aem	334	11	groups	group	NNS
cord-322904-9mta0aem	334	12	are	be	VBP
cord-322904-9mta0aem	334	13	sufficient	sufficient	JJ
cord-322904-9mta0aem	334	14	to	to	TO
cord-322904-9mta0aem	334	15	position	position	VB
cord-322904-9mta0aem	334	16	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	334	17	correctly	correctly	RB
cord-322904-9mta0aem	334	18	on	on	IN
cord-322904-9mta0aem	334	19	the	the	DT
cord-322904-9mta0aem	334	20	protein	protein	NN
cord-322904-9mta0aem	334	21	surface	surface	NN
cord-322904-9mta0aem	334	22	,	,	,
cord-322904-9mta0aem	334	23	most	most	JJS
cord-322904-9mta0aem	334	24	attachment	attachment	NN
cord-322904-9mta0aem	334	25	complexes	complex	NNS
cord-322904-9mta0aem	334	26	feature	feature	VBP
cord-322904-9mta0aem	334	27	contacts	contact	NNS
cord-322904-9mta0aem	334	28	with	with	IN
cord-322904-9mta0aem	334	29	the	the	DT
cord-322904-9mta0aem	334	30	polar	polar	JJ
cord-322904-9mta0aem	334	31	and	and	CC
cord-322904-9mta0aem	334	32	flexible	flexible	JJ
cord-322904-9mta0aem	334	33	glycerol	glycerol	NN
cord-322904-9mta0aem	334	34	moiety	moiety	NN
cord-322904-9mta0aem	334	35	.	.	.
cord-322904-9mta0aem	335	1	This	this	DT
cord-322904-9mta0aem	335	2	group	group	NN
cord-322904-9mta0aem	335	3	protrudes	protrude	VBZ
cord-322904-9mta0aem	335	4	away	away	RB
cord-322904-9mta0aem	335	5	from	from	IN
cord-322904-9mta0aem	335	6	the	the	DT
cord-322904-9mta0aem	335	7	protein	protein	NN
cord-322904-9mta0aem	335	8	in	in	IN
cord-322904-9mta0aem	335	9	the	the	DT
cord-322904-9mta0aem	335	10	mPyV	mpyv	JJ
cord-322904-9mta0aem	335	11	VP1	VP1	NNP
cord-322904-9mta0aem	335	12	and	and	CC
cord-322904-9mta0aem	335	13	Ad37	Ad37	NNP
cord-322904-9mta0aem	335	14	complexes	complex	NNS
cord-322904-9mta0aem	335	15	(	(	-LRB-
cord-322904-9mta0aem	335	16	Figs	fig	NNS
cord-322904-9mta0aem	335	17	.	.	.
cord-322904-9mta0aem	336	1	4C	4C	NNP
cord-322904-9mta0aem	336	2	and	and	CC
cord-322904-9mta0aem	336	3	E	E	NNP
cord-322904-9mta0aem	336	4	)	)	-RRB-
cord-322904-9mta0aem	336	5	,	,	,
cord-322904-9mta0aem	336	6	but	but	CC
cord-322904-9mta0aem	336	7	is	be	VBZ
cord-322904-9mta0aem	336	8	recognized	recognize	VBN
cord-322904-9mta0aem	336	9	by	by	IN
cord-322904-9mta0aem	336	10	a	a	DT
cord-322904-9mta0aem	336	11	number	number	NN
cord-322904-9mta0aem	336	12	of	of	IN
cord-322904-9mta0aem	336	13	contacts	contact	NNS
cord-322904-9mta0aem	336	14	in	in	IN
cord-322904-9mta0aem	336	15	the	the	DT
cord-322904-9mta0aem	336	16	other	other	JJ
cord-322904-9mta0aem	336	17	complexes	complex	NNS
cord-322904-9mta0aem	336	18	.	.	.
cord-322904-9mta0aem	337	1	There	there	EX
cord-322904-9mta0aem	337	2	are	be	VBP
cord-322904-9mta0aem	337	3	hydrogen	hydrogen	NN
cord-322904-9mta0aem	337	4	bonds	bond	NNS
cord-322904-9mta0aem	337	5	to	to	IN
cord-322904-9mta0aem	337	6	O8	O8	NNP
cord-322904-9mta0aem	337	7	and	and	CC
cord-322904-9mta0aem	337	8	O9	O9	NNP
cord-322904-9mta0aem	337	9	by	by	IN
cord-322904-9mta0aem	337	10	each	each	DT
cord-322904-9mta0aem	337	11	of	of	IN
cord-322904-9mta0aem	337	12	SV40	SV40	NNP
cord-322904-9mta0aem	337	13	VP1	VP1	NNP
cord-322904-9mta0aem	337	14	,	,	,
cord-322904-9mta0aem	337	15	Influenza	Influenza	NNP
cord-322904-9mta0aem	337	16	HA	HA	NNP
cord-322904-9mta0aem	337	17	and	and	CC
cord-322904-9mta0aem	337	18	Rotavirus	Rotavirus	NNP
cord-322904-9mta0aem	337	19	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	337	20	that	that	WDT
cord-322904-9mta0aem	337	21	are	be	VBP
cord-322904-9mta0aem	337	22	formed	form	VBN
cord-322904-9mta0aem	337	23	by	by	IN
cord-322904-9mta0aem	337	24	Ser	Ser	NNP
cord-322904-9mta0aem	337	25	,	,	,
cord-322904-9mta0aem	337	26	Tyr	Tyr	NNP
cord-322904-9mta0aem	337	27	and	and	CC
cord-322904-9mta0aem	337	28	Arg	Arg	NNP
cord-322904-9mta0aem	337	29	side	side	NN
cord-322904-9mta0aem	337	30	chains	chain	NNS
cord-322904-9mta0aem	337	31	(	(	-LRB-
cord-322904-9mta0aem	337	32	Figs	fig	NNS
cord-322904-9mta0aem	337	33	.	.	.
cord-322904-9mta0aem	338	1	4B	4B	NNP
cord-322904-9mta0aem	338	2	,	,	,
cord-322904-9mta0aem	338	3	D	D	NNP
cord-322904-9mta0aem	338	4	,	,	,
cord-322904-9mta0aem	338	5	F	F	NNP
cord-322904-9mta0aem	338	6	)	)	-RRB-
cord-322904-9mta0aem	338	7	.	.	.
cord-322904-9mta0aem	339	1	In	in	IN
cord-322904-9mta0aem	339	2	addition	addition	NN
cord-322904-9mta0aem	339	3	,	,	,
cord-322904-9mta0aem	339	4	the	the	DT
cord-322904-9mta0aem	339	5	glycerol	glycerol	NN
cord-322904-9mta0aem	339	6	chain	chain	NN
cord-322904-9mta0aem	339	7	lies	lie	VBZ
cord-322904-9mta0aem	339	8	in	in	IN
cord-322904-9mta0aem	339	9	a	a	DT
cord-322904-9mta0aem	339	10	shallow	shallow	JJ
cord-322904-9mta0aem	339	11	pocket	pocket	NN
cord-322904-9mta0aem	339	12	in	in	IN
cord-322904-9mta0aem	339	13	all	all	DT
cord-322904-9mta0aem	339	14	of	of	IN
cord-322904-9mta0aem	339	15	these	these	DT
cord-322904-9mta0aem	339	16	complexes	complex	NNS
cord-322904-9mta0aem	339	17	and	and	CC
cord-322904-9mta0aem	339	18	makes	make	VBZ
cord-322904-9mta0aem	339	19	van	van	NNP
cord-322904-9mta0aem	339	20	der	der	NNP
cord-322904-9mta0aem	339	21	Waals	Waals	NNP
cord-322904-9mta0aem	339	22	contacts	contact	NNS
cord-322904-9mta0aem	339	23	to	to	IN
cord-322904-9mta0aem	339	24	residues	residue	NNS
cord-322904-9mta0aem	339	25	that	that	WDT
cord-322904-9mta0aem	339	26	confer	confer	VBP
cord-322904-9mta0aem	339	27	shape	shape	NN
cord-322904-9mta0aem	339	28	specificity	specificity	NN
cord-322904-9mta0aem	339	29	.	.	.
cord-322904-9mta0aem	340	1	In	in	IN
cord-322904-9mta0aem	340	2	summary	summary	NN
cord-322904-9mta0aem	340	3	,	,	,
cord-322904-9mta0aem	340	4	while	while	IN
cord-322904-9mta0aem	340	5	all	all	DT
cord-322904-9mta0aem	340	6	of	of	IN
cord-322904-9mta0aem	340	7	the	the	DT
cord-322904-9mta0aem	340	8	binding	bind	VBG
cord-322904-9mta0aem	340	9	sites	site	NNS
cord-322904-9mta0aem	340	10	recognize	recognize	VBP
cord-322904-9mta0aem	340	11	the	the	DT
cord-322904-9mta0aem	340	12	carboxylate	carboxylate	NNP
cord-322904-9mta0aem	340	13	group	group	NN
cord-322904-9mta0aem	340	14	and	and	CC
cord-322904-9mta0aem	340	15	form	form	VB
cord-322904-9mta0aem	340	16	a	a	DT
cord-322904-9mta0aem	340	17	hydrogen	hydrogen	NN
cord-322904-9mta0aem	340	18	bond	bond	NN
cord-322904-9mta0aem	340	19	to	to	IN
cord-322904-9mta0aem	340	20	the	the	DT
cord-322904-9mta0aem	340	21	N	N	NNP
cord-322904-9mta0aem	340	22	-	-	HYPH
cord-322904-9mta0aem	340	23	acetyl	acetyl	NNP
cord-322904-9mta0aem	340	24	group	group	NN
cord-322904-9mta0aem	340	25	,	,	,
cord-322904-9mta0aem	340	26	only	only	RB
cord-322904-9mta0aem	340	27	some	some	DT
cord-322904-9mta0aem	340	28	(	(	-LRB-
cord-322904-9mta0aem	340	29	SV40	SV40	NNP
cord-322904-9mta0aem	340	30	VP1	vp1	NN
cord-322904-9mta0aem	340	31	,	,	,
cord-322904-9mta0aem	340	32	Influenza	Influenza	NNP
cord-322904-9mta0aem	340	33	HA	HA	NNP
cord-322904-9mta0aem	340	34	and	and	CC
cord-322904-9mta0aem	340	35	Rotavirus	Rotavirus	NNP
cord-322904-9mta0aem	340	36	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	340	37	)	)	-RRB-
cord-322904-9mta0aem	340	38	contact	contact	VBP
cord-322904-9mta0aem	340	39	the	the	DT
cord-322904-9mta0aem	340	40	glycerol	glycerol	NN
cord-322904-9mta0aem	340	41	chain	chain	NN
cord-322904-9mta0aem	340	42	both	both	DT
cord-322904-9mta0aem	340	43	by	by	IN
cord-322904-9mta0aem	340	44	hydrogen	hydrogen	NN
cord-322904-9mta0aem	340	45	bonds	bond	NNS
cord-322904-9mta0aem	340	46	and	and	CC
cord-322904-9mta0aem	340	47	shape	shape	NN
cord-322904-9mta0aem	340	48	complementarity	complementarity	NN
cord-322904-9mta0aem	340	49	.	.	.
cord-322904-9mta0aem	341	1	In	in	IN
cord-322904-9mta0aem	341	2	addition	addition	NN
cord-322904-9mta0aem	341	3	,	,	,
cord-322904-9mta0aem	341	4	most	most	RBS
cord-322904-9mta0aem	341	5	also	also	RB
cord-322904-9mta0aem	341	6	feature	feature	VBP
cord-322904-9mta0aem	341	7	a	a	DT
cord-322904-9mta0aem	341	8	depression	depression	NN
cord-322904-9mta0aem	341	9	that	that	WDT
cord-322904-9mta0aem	341	10	accommodates	accommodate	VBZ
cord-322904-9mta0aem	341	11	the	the	DT
cord-322904-9mta0aem	341	12	methyl	methyl	NN
cord-322904-9mta0aem	341	13	group	group	NN
cord-322904-9mta0aem	341	14	of	of	IN
cord-322904-9mta0aem	341	15	the	the	DT
cord-322904-9mta0aem	341	16	N	N	NNP
cord-322904-9mta0aem	341	17	-	-	HYPH
cord-322904-9mta0aem	341	18	acetyl	acetyl	NNP
cord-322904-9mta0aem	341	19	moiety	moiety	NN
cord-322904-9mta0aem	341	20	.	.	.
cord-322904-9mta0aem	342	1	Since	since	IN
cord-322904-9mta0aem	342	2	all	all	DT
cord-322904-9mta0aem	342	3	binding	bind	VBG
cord-322904-9mta0aem	342	4	surfaces	surface	NNS
cord-322904-9mta0aem	342	5	are	be	VBP
cord-322904-9mta0aem	342	6	exposed	expose	VBN
cord-322904-9mta0aem	342	7	,	,	,
cord-322904-9mta0aem	342	8	the	the	DT
cord-322904-9mta0aem	342	9	interactions	interaction	NNS
cord-322904-9mta0aem	342	10	determining	determine	VBG
cord-322904-9mta0aem	342	11	NeuNAc	neunac	JJ
cord-322904-9mta0aem	342	12	binding	bind	VBG
cord-322904-9mta0aem	342	13	lie	lie	NN
cord-322904-9mta0aem	342	14	in	in	IN
cord-322904-9mta0aem	342	15	the	the	DT
cord-322904-9mta0aem	342	16	rather	rather	RB
cord-322904-9mta0aem	342	17	polar	polar	JJ
cord-322904-9mta0aem	342	18	environment	environment	NN
cord-322904-9mta0aem	342	19	of	of	IN
cord-322904-9mta0aem	342	20	the	the	DT
cord-322904-9mta0aem	342	21	protein	protein	NN
cord-322904-9mta0aem	342	22	surface	surface	NN
cord-322904-9mta0aem	342	23	.	.	.
cord-322904-9mta0aem	343	1	The	the	DT
cord-322904-9mta0aem	343	2	polar	polar	JJ
cord-322904-9mta0aem	343	3	interactions	interaction	NNS
cord-322904-9mta0aem	343	4	are	be	VBP
cord-322904-9mta0aem	343	5	therefore	therefore	RB
cord-322904-9mta0aem	343	6	probably	probably	RB
cord-322904-9mta0aem	343	7	quite	quite	RB
cord-322904-9mta0aem	343	8	weak	weak	JJ
cord-322904-9mta0aem	343	9	.	.	.
cord-322904-9mta0aem	344	1	Hydrogen	hydrogen	NN
cord-322904-9mta0aem	344	2	bonds	bond	NNS
cord-322904-9mta0aem	344	3	between	between	IN
cord-322904-9mta0aem	344	4	sialic	sialic	JJ
cord-322904-9mta0aem	344	5	acid	acid	NN
cord-322904-9mta0aem	344	6	and	and	CC
cord-322904-9mta0aem	344	7	protein	protein	NN
cord-322904-9mta0aem	344	8	atoms	atom	NNS
cord-322904-9mta0aem	344	9	can	can	MD
cord-322904-9mta0aem	344	10	be	be	VB
cord-322904-9mta0aem	344	11	replaced	replace	VBN
cord-322904-9mta0aem	344	12	by	by	IN
cord-322904-9mta0aem	344	13	contacts	contact	NNS
cord-322904-9mta0aem	344	14	between	between	IN
cord-322904-9mta0aem	344	15	water	water	NN
cord-322904-9mta0aem	344	16	molecules	molecule	NNS
cord-322904-9mta0aem	344	17	and	and	CC
cord-322904-9mta0aem	344	18	protein	protein	NN
cord-322904-9mta0aem	344	19	atoms	atom	NNS
cord-322904-9mta0aem	344	20	without	without	IN
cord-322904-9mta0aem	344	21	much	much	JJ
cord-322904-9mta0aem	344	22	difference	difference	NN
cord-322904-9mta0aem	344	23	in	in	IN
cord-322904-9mta0aem	344	24	energy	energy	NN
cord-322904-9mta0aem	344	25	.	.	.
cord-322904-9mta0aem	345	1	Salt	salt	NN
cord-322904-9mta0aem	345	2	bridges	bridge	NNS
cord-322904-9mta0aem	345	3	in	in	IN
cord-322904-9mta0aem	345	4	aqueous	aqueous	JJ
cord-322904-9mta0aem	345	5	solution	solution	NN
cord-322904-9mta0aem	345	6	also	also	RB
cord-322904-9mta0aem	345	7	possess	possess	VBP
cord-322904-9mta0aem	345	8	less	less	JJR
cord-322904-9mta0aem	345	9	energy	energy	NN
cord-322904-9mta0aem	345	10	than	than	IN
cord-322904-9mta0aem	345	11	salt	salt	NN
cord-322904-9mta0aem	345	12	bridges	bridge	NNS
cord-322904-9mta0aem	345	13	that	that	WDT
cord-322904-9mta0aem	345	14	are	be	VBP
cord-322904-9mta0aem	345	15	located	locate	VBN
cord-322904-9mta0aem	345	16	in	in	IN
cord-322904-9mta0aem	345	17	a	a	DT
cord-322904-9mta0aem	345	18	partially	partially	RB
cord-322904-9mta0aem	345	19	hydrophobic	hydrophobic	JJ
cord-322904-9mta0aem	345	20	,	,	,
cord-322904-9mta0aem	345	21	solvent	solvent	NN
cord-322904-9mta0aem	345	22	-	-	HYPH
cord-322904-9mta0aem	345	23	inaccessible	inaccessible	JJ
cord-322904-9mta0aem	345	24	environment	environment	NN
cord-322904-9mta0aem	345	25	.	.	.
cord-322904-9mta0aem	346	1	Likewise	likewise	RB
cord-322904-9mta0aem	346	2	,	,	,
cord-322904-9mta0aem	346	3	the	the	DT
cord-322904-9mta0aem	346	4	non	non	JJ
cord-322904-9mta0aem	346	5	-	-	JJ
cord-322904-9mta0aem	346	6	polar	polar	JJ
cord-322904-9mta0aem	346	7	van	van	NNP
cord-322904-9mta0aem	346	8	der	der	NNP
cord-322904-9mta0aem	346	9	Waals	Waals	NNP
cord-322904-9mta0aem	346	10	interactions	interaction	NNS
cord-322904-9mta0aem	346	11	between	between	IN
cord-322904-9mta0aem	346	12	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	346	13	and	and	CC
cord-322904-9mta0aem	346	14	protein	protein	NN
cord-322904-9mta0aem	346	15	are	be	VBP
cord-322904-9mta0aem	346	16	also	also	RB
cord-322904-9mta0aem	346	17	not	not	RB
cord-322904-9mta0aem	346	18	very	very	RB
cord-322904-9mta0aem	346	19	strong	strong	JJ
cord-322904-9mta0aem	346	20	as	as	IN
cord-322904-9mta0aem	346	21	such	such	JJ
cord-322904-9mta0aem	346	22	interactions	interaction	NNS
cord-322904-9mta0aem	346	23	increase	increase	VBP
cord-322904-9mta0aem	346	24	in	in	IN
cord-322904-9mta0aem	346	25	strength	strength	NN
cord-322904-9mta0aem	346	26	with	with	IN
cord-322904-9mta0aem	346	27	the	the	DT
cord-322904-9mta0aem	346	28	area	area	NN
cord-322904-9mta0aem	346	29	of	of	IN
cord-322904-9mta0aem	346	30	surface	surface	NN
cord-322904-9mta0aem	346	31	buried	bury	VBN
cord-322904-9mta0aem	346	32	in	in	IN
cord-322904-9mta0aem	346	33	the	the	DT
cord-322904-9mta0aem	346	34	contact	contact	NN
cord-322904-9mta0aem	346	35	.	.	.
cord-322904-9mta0aem	347	1	Most	Most	JJS
cord-322904-9mta0aem	347	2	of	of	IN
cord-322904-9mta0aem	347	3	the	the	DT
cord-322904-9mta0aem	347	4	contacts	contact	NNS
cord-322904-9mta0aem	347	5	described	describe	VBN
cord-322904-9mta0aem	347	6	above	above	IN
cord-322904-9mta0aem	347	7	exclude	exclude	VB
cord-322904-9mta0aem	347	8	rather	rather	RB
cord-322904-9mta0aem	347	9	small	small	JJ
cord-322904-9mta0aem	347	10	areas	area	NNS
cord-322904-9mta0aem	347	11	from	from	IN
cord-322904-9mta0aem	347	12	solvent	solvent	NN
cord-322904-9mta0aem	347	13	compared	compare	VBN
cord-322904-9mta0aem	347	14	to	to	IN
cord-322904-9mta0aem	347	15	the	the	DT
cord-322904-9mta0aem	347	16	extensive	extensive	JJ
cord-322904-9mta0aem	347	17	interfaces	interface	NNS
cord-322904-9mta0aem	347	18	found	find	VBN
cord-322904-9mta0aem	347	19	in	in	IN
cord-322904-9mta0aem	347	20	protein	protein	NN
cord-322904-9mta0aem	347	21	-	-	HYPH
cord-322904-9mta0aem	347	22	protein	protein	NN
cord-322904-9mta0aem	347	23	complexes	complex	NNS
cord-322904-9mta0aem	347	24	.	.	.
cord-322904-9mta0aem	348	1	The	the	DT
cord-322904-9mta0aem	348	2	observed	observed	JJ
cord-322904-9mta0aem	348	3	,	,	,
cord-322904-9mta0aem	348	4	relatively	relatively	RB
cord-322904-9mta0aem	348	5	weak	weak	JJ
cord-322904-9mta0aem	348	6	interactions	interaction	NNS
cord-322904-9mta0aem	348	7	are	be	VBP
cord-322904-9mta0aem	348	8	consistent	consistent	JJ
cord-322904-9mta0aem	348	9	with	with	IN
cord-322904-9mta0aem	348	10	the	the	DT
cord-322904-9mta0aem	348	11	experimentally	experimentally	RB
cord-322904-9mta0aem	348	12	-	-	HYPH
cord-322904-9mta0aem	348	13	determined	determine	VBN
cord-322904-9mta0aem	348	14	millimolar	millimolar	JJ
cord-322904-9mta0aem	348	15	affinities	affinity	NNS
cord-322904-9mta0aem	348	16	for	for	IN
cord-322904-9mta0aem	348	17	the	the	DT
cord-322904-9mta0aem	348	18	proteinglycan	proteinglycan	JJ
cord-322904-9mta0aem	348	19	complexes	complex	NNS
cord-322904-9mta0aem	348	20	.	.	.
cord-322904-9mta0aem	349	1	The	the	DT
cord-322904-9mta0aem	349	2	shallow	shallow	JJ
cord-322904-9mta0aem	349	3	binding	binding	JJ
cord-322904-9mta0aem	349	4	sites	site	NNS
cord-322904-9mta0aem	349	5	of	of	IN
cord-322904-9mta0aem	349	6	attachment	attachment	NN
cord-322904-9mta0aem	349	7	proteins	protein	NNS
cord-322904-9mta0aem	349	8	do	do	VBP
cord-322904-9mta0aem	349	9	not	not	RB
cord-322904-9mta0aem	349	10	exclude	exclude	VB
cord-322904-9mta0aem	349	11	binding	binding	NN
cord-322904-9mta0aem	349	12	of	of	IN
cord-322904-9mta0aem	349	13	incorrect	incorrect	JJ
cord-322904-9mta0aem	349	14	ligands	ligand	NNS
cord-322904-9mta0aem	349	15	by	by	IN
cord-322904-9mta0aem	349	16	steric	steric	JJ
cord-322904-9mta0aem	349	17	clashes	clash	NNS
cord-322904-9mta0aem	349	18	.	.	.
cord-322904-9mta0aem	350	1	Instead	instead	RB
cord-322904-9mta0aem	350	2	,	,	,
cord-322904-9mta0aem	350	3	specificity	specificity	NN
cord-322904-9mta0aem	350	4	is	be	VBZ
cord-322904-9mta0aem	350	5	provided	provide	VBN
cord-322904-9mta0aem	350	6	by	by	IN
cord-322904-9mta0aem	350	7	favorable	favorable	JJ
cord-322904-9mta0aem	350	8	interactions	interaction	NNS
cord-322904-9mta0aem	350	9	that	that	WDT
cord-322904-9mta0aem	350	10	are	be	VBP
cord-322904-9mta0aem	350	11	spaced	space	VBN
cord-322904-9mta0aem	350	12	in	in	IN
cord-322904-9mta0aem	350	13	a	a	DT
cord-322904-9mta0aem	350	14	way	way	NN
cord-322904-9mta0aem	350	15	that	that	WDT
cord-322904-9mta0aem	350	16	only	only	RB
cord-322904-9mta0aem	350	17	the	the	DT
cord-322904-9mta0aem	350	18	correct	correct	JJ
cord-322904-9mta0aem	350	19	ligand	ligand	NN
cord-322904-9mta0aem	350	20	can	can	MD
cord-322904-9mta0aem	350	21	engage	engage	VB
cord-322904-9mta0aem	350	22	in	in	IN
cord-322904-9mta0aem	350	23	all	all	DT
cord-322904-9mta0aem	350	24	contacts	contact	NNS
cord-322904-9mta0aem	350	25	.	.	.
cord-322904-9mta0aem	351	1	In	in	IN
cord-322904-9mta0aem	351	2	the	the	DT
cord-322904-9mta0aem	351	3	case	case	NN
cord-322904-9mta0aem	351	4	of	of	IN
cord-322904-9mta0aem	351	5	Influenza	Influenza	NNP
cord-322904-9mta0aem	351	6	HA	HA	NNP
cord-322904-9mta0aem	351	7	,	,	,
cord-322904-9mta0aem	351	8	mPyV	mpyv	JJ
cord-322904-9mta0aem	351	9	VP1	vp1	NN
cord-322904-9mta0aem	351	10	and	and	CC
cord-322904-9mta0aem	351	11	SV40	SV40	NNP
cord-322904-9mta0aem	351	12	VP1	VP1	NNP
cord-322904-9mta0aem	351	13	,	,	,
cord-322904-9mta0aem	351	14	sialic	sialic	JJ
cord-322904-9mta0aem	351	15	acid	acid	NN
cord-322904-9mta0aem	351	16	by	by	IN
cord-322904-9mta0aem	351	17	itself	-PRON-	PRP
cord-322904-9mta0aem	351	18	is	be	VBZ
cord-322904-9mta0aem	351	19	not	not	RB
cord-322904-9mta0aem	351	20	sufficient	sufficient	JJ
cord-322904-9mta0aem	351	21	for	for	IN
cord-322904-9mta0aem	351	22	binding	bind	VBG
cord-322904-9mta0aem	351	23	,	,	,
cord-322904-9mta0aem	351	24	but	but	CC
cord-322904-9mta0aem	351	25	additional	additional	JJ
cord-322904-9mta0aem	351	26	sugars	sugar	NNS
cord-322904-9mta0aem	351	27	are	be	VBP
cord-322904-9mta0aem	351	28	also	also	RB
cord-322904-9mta0aem	351	29	needed	need	VBN
cord-322904-9mta0aem	351	30	for	for	IN
cord-322904-9mta0aem	351	31	the	the	DT
cord-322904-9mta0aem	351	32	interaction	interaction	NN
cord-322904-9mta0aem	351	33	.	.	.
cord-322904-9mta0aem	352	1	Two	two	CD
cord-322904-9mta0aem	352	2	of	of	IN
cord-322904-9mta0aem	352	3	the	the	DT
cord-322904-9mta0aem	352	4	viruses	virus	NNS
cord-322904-9mta0aem	352	5	mentioned	mention	VBN
cord-322904-9mta0aem	352	6	before	before	RB
cord-322904-9mta0aem	352	7	,	,	,
cord-322904-9mta0aem	352	8	Rhesus	Rhesus	NNP
cord-322904-9mta0aem	352	9	Rotavirus	Rotavirus	NNP
cord-322904-9mta0aem	352	10	and	and	CC
cord-322904-9mta0aem	352	11	Ad37	Ad37	NNP
cord-322904-9mta0aem	352	12	,	,	,
cord-322904-9mta0aem	352	13	appear	appear	VBP
cord-322904-9mta0aem	352	14	to	to	TO
cord-322904-9mta0aem	352	15	bind	bind	VB
cord-322904-9mta0aem	352	16	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	352	17	relatively	relatively	RB
cord-322904-9mta0aem	352	18	indiscriminately	indiscriminately	RB
cord-322904-9mta0aem	352	19	,	,	,
cord-322904-9mta0aem	352	20	although	although	IN
cord-322904-9mta0aem	352	21	it	-PRON-	PRP
cord-322904-9mta0aem	352	22	is	be	VBZ
cord-322904-9mta0aem	352	23	possible	possible	JJ
cord-322904-9mta0aem	352	24	that	that	IN
cord-322904-9mta0aem	352	25	additional	additional	JJ
cord-322904-9mta0aem	352	26	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	352	27	may	may	MD
cord-322904-9mta0aem	352	28	contribute	contribute	VB
cord-322904-9mta0aem	352	29	to	to	IN
cord-322904-9mta0aem	352	30	binding	bind	VBG
cord-322904-9mta0aem	352	31	.	.	.
cord-322904-9mta0aem	353	1	mPyV	mpyv	JJ
cord-322904-9mta0aem	353	2	,	,	,
cord-322904-9mta0aem	353	3	SV40	SV40	NNP
cord-322904-9mta0aem	353	4	and	and	CC
cord-322904-9mta0aem	353	5	different	different	JJ
cord-322904-9mta0aem	353	6	strains	strain	NNS
cord-322904-9mta0aem	353	7	of	of	IN
cord-322904-9mta0aem	353	8	influenzaviruses	influenzaviruse	NNS
cord-322904-9mta0aem	353	9	,	,	,
cord-322904-9mta0aem	353	10	however	however	RB
cord-322904-9mta0aem	353	11	,	,	,
cord-322904-9mta0aem	353	12	have	have	VBP
cord-322904-9mta0aem	353	13	distinct	distinct	JJ
cord-322904-9mta0aem	353	14	specificities	specificity	NNS
cord-322904-9mta0aem	353	15	for	for	IN
cord-322904-9mta0aem	353	16	the	the	DT
cord-322904-9mta0aem	353	17	structural	structural	JJ
cord-322904-9mta0aem	353	18	contexts	contexts	NN
cord-322904-9mta0aem	353	19	of	of	IN
cord-322904-9mta0aem	353	20	the	the	DT
cord-322904-9mta0aem	353	21	sialic	sialic	JJ
cord-322904-9mta0aem	353	22	acid	acid	NN
cord-322904-9mta0aem	353	23	.	.	.
cord-322904-9mta0aem	354	1	mPyV	mpyv	JJ
cord-322904-9mta0aem	354	2	VP1	VP1	NNP
cord-322904-9mta0aem	354	3	binds	bind	VBZ
cord-322904-9mta0aem	354	4	carbohydrates	carbohydrate	NNS
cord-322904-9mta0aem	354	5	containing	contain	VBG
cord-322904-9mta0aem	354	6	a	a	DT
cord-322904-9mta0aem	354	7	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	354	8	-	-	HYPH
cord-322904-9mta0aem	354	9	α2,3-Gal	α2,3-gal	NN
cord-322904-9mta0aem	354	10	motif	motif	NN
cord-322904-9mta0aem	354	11	that	that	WDT
cord-322904-9mta0aem	354	12	is	be	VBZ
cord-322904-9mta0aem	354	13	unbranched	unbranched	JJ
cord-322904-9mta0aem	354	14	at	at	IN
cord-322904-9mta0aem	354	15	the	the	DT
cord-322904-9mta0aem	354	16	Gal	Gal	NNP
cord-322904-9mta0aem	354	17	position	position	NN
cord-322904-9mta0aem	354	18	(	(	-LRB-
cord-322904-9mta0aem	354	19	Cahan	Cahan	NNP
cord-322904-9mta0aem	354	20	et	et	NNP
cord-322904-9mta0aem	354	21	al	al	NNP
cord-322904-9mta0aem	354	22	.	.	NNP
cord-322904-9mta0aem	354	23	,	,	,
cord-322904-9mta0aem	354	24	1983	1983	CD
cord-322904-9mta0aem	354	25	)	)	-RRB-
cord-322904-9mta0aem	354	26	.	.	.
cord-322904-9mta0aem	355	1	The	the	DT
cord-322904-9mta0aem	355	2	Gal	Gal	NNP
cord-322904-9mta0aem	355	3	moiety	moiety	NN
cord-322904-9mta0aem	355	4	is	be	VBZ
cord-322904-9mta0aem	355	5	recognized	recognize	VBN
cord-322904-9mta0aem	355	6	by	by	IN
cord-322904-9mta0aem	355	7	a	a	DT
cord-322904-9mta0aem	355	8	hydrogen	hydrogen	NN
cord-322904-9mta0aem	355	9	bond	bond	NN
cord-322904-9mta0aem	355	10	between	between	IN
cord-322904-9mta0aem	355	11	the	the	DT
cord-322904-9mta0aem	355	12	backbone	backbone	NN
cord-322904-9mta0aem	355	13	carbonyl	carbonyl	NN
cord-322904-9mta0aem	355	14	group	group	NN
cord-322904-9mta0aem	355	15	of	of	IN
cord-322904-9mta0aem	355	16	Gly78	Gly78	NNP
cord-322904-9mta0aem	355	17	and	and	CC
cord-322904-9mta0aem	355	18	the	the	DT
cord-322904-9mta0aem	355	19	distinctive	distinctive	JJ
cord-322904-9mta0aem	355	20	axial	axial	JJ
cord-322904-9mta0aem	355	21	O4	O4	NNP
cord-322904-9mta0aem	355	22	hydroxyl	hydroxyl	NN
cord-322904-9mta0aem	355	23	group	group	NN
cord-322904-9mta0aem	355	24	of	of	IN
cord-322904-9mta0aem	355	25	Gal	Gal	NNP
cord-322904-9mta0aem	355	26	(	(	-LRB-
cord-322904-9mta0aem	355	27	Stehle	Stehle	NNP
cord-322904-9mta0aem	355	28	and	and	CC
cord-322904-9mta0aem	355	29	Harrison	Harrison	NNP
cord-322904-9mta0aem	355	30	,	,	,
cord-322904-9mta0aem	355	31	1997	1997	CD
cord-322904-9mta0aem	355	32	)	)	-RRB-
cord-322904-9mta0aem	355	33	.	.	.
cord-322904-9mta0aem	356	1	The	the	DT
cord-322904-9mta0aem	356	2	lack	lack	NN
cord-322904-9mta0aem	356	3	of	of	IN
cord-322904-9mta0aem	356	4	a	a	DT
cord-322904-9mta0aem	356	5	side	side	NN
cord-322904-9mta0aem	356	6	chain	chain	NN
cord-322904-9mta0aem	356	7	in	in	IN
cord-322904-9mta0aem	356	8	Gly78	Gly78	NNP
cord-322904-9mta0aem	356	9	also	also	RB
cord-322904-9mta0aem	356	10	confers	confer	VBZ
cord-322904-9mta0aem	356	11	binding	bind	VBG
cord-322904-9mta0aem	356	12	specificity	specificity	NN
cord-322904-9mta0aem	356	13	since	since	IN
cord-322904-9mta0aem	356	14	the	the	DT
cord-322904-9mta0aem	356	15	presence	presence	NN
cord-322904-9mta0aem	356	16	of	of	IN
cord-322904-9mta0aem	356	17	even	even	RB
cord-322904-9mta0aem	356	18	a	a	DT
cord-322904-9mta0aem	356	19	small	small	JJ
cord-322904-9mta0aem	356	20	side	side	NN
cord-322904-9mta0aem	356	21	chain	chain	NN
cord-322904-9mta0aem	356	22	in	in	IN
cord-322904-9mta0aem	356	23	this	this	DT
cord-322904-9mta0aem	356	24	position	position	NN
cord-322904-9mta0aem	356	25	would	would	MD
cord-322904-9mta0aem	356	26	cause	cause	VB
cord-322904-9mta0aem	356	27	sterical	sterical	JJ
cord-322904-9mta0aem	356	28	clashes	clash	NNS
cord-322904-9mta0aem	356	29	with	with	IN
cord-322904-9mta0aem	356	30	the	the	DT
cord-322904-9mta0aem	356	31	Gal	Gal	NNP
cord-322904-9mta0aem	356	32	and	and	CC
cord-322904-9mta0aem	356	33	abolish	abolish	VB
cord-322904-9mta0aem	356	34	binding	binding	NN
cord-322904-9mta0aem	356	35	.	.	.
cord-322904-9mta0aem	357	1	The	the	DT
cord-322904-9mta0aem	357	2	architecture	architecture	NN
cord-322904-9mta0aem	357	3	of	of	IN
cord-322904-9mta0aem	357	4	the	the	DT
cord-322904-9mta0aem	357	5	binding	binding	NN
cord-322904-9mta0aem	357	6	site	site	NN
cord-322904-9mta0aem	357	7	accepts	accept	VBZ
cord-322904-9mta0aem	357	8	only	only	RB
cord-322904-9mta0aem	357	9	one	one	CD
cord-322904-9mta0aem	357	10	conformation	conformation	NN
cord-322904-9mta0aem	357	11	of	of	IN
cord-322904-9mta0aem	357	12	the	the	DT
cord-322904-9mta0aem	357	13	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	357	14	-	-	HYPH
cord-322904-9mta0aem	357	15	α2,3-Gal	α2,3-gal	CD
cord-322904-9mta0aem	357	16	glycosidic	glycosidic	JJ
cord-322904-9mta0aem	357	17	linkage	linkage	NN
cord-322904-9mta0aem	357	18	.	.	.
cord-322904-9mta0aem	358	1	This	this	DT
cord-322904-9mta0aem	358	2	conformation	conformation	NN
cord-322904-9mta0aem	358	3	is	be	VBZ
cord-322904-9mta0aem	358	4	stabilized	stabilize	VBN
cord-322904-9mta0aem	358	5	by	by	IN
cord-322904-9mta0aem	358	6	an	an	DT
cord-322904-9mta0aem	358	7	internal	internal	JJ
cord-322904-9mta0aem	358	8	hydrogen	hydrogen	NN
cord-322904-9mta0aem	358	9	bond	bond	NN
cord-322904-9mta0aem	358	10	and	and	CC
cord-322904-9mta0aem	358	11	also	also	RB
cord-322904-9mta0aem	358	12	occurs	occur	VBZ
cord-322904-9mta0aem	358	13	in	in	IN
cord-322904-9mta0aem	358	14	solution	solution	NN
cord-322904-9mta0aem	358	15	,	,	,
cord-322904-9mta0aem	358	16	but	but	CC
cord-322904-9mta0aem	358	17	it	-PRON-	PRP
cord-322904-9mta0aem	358	18	could	could	MD
cord-322904-9mta0aem	358	19	not	not	RB
cord-322904-9mta0aem	358	20	be	be	VB
cord-322904-9mta0aem	358	21	adopted	adopt	VBN
cord-322904-9mta0aem	358	22	by	by	IN
cord-322904-9mta0aem	358	23	compounds	compound	NNS
cord-322904-9mta0aem	358	24	that	that	WDT
cord-322904-9mta0aem	358	25	are	be	VBP
cord-322904-9mta0aem	358	26	branched	branch	VBN
cord-322904-9mta0aem	358	27	at	at	IN
cord-322904-9mta0aem	358	28	the	the	DT
cord-322904-9mta0aem	358	29	Gal	Gal	NNP
cord-322904-9mta0aem	358	30	residue	residue	NN
cord-322904-9mta0aem	358	31	due	due	IN
cord-322904-9mta0aem	358	32	to	to	IN
cord-322904-9mta0aem	358	33	steric	steric	JJ
cord-322904-9mta0aem	358	34	clashes	clash	NNS
cord-322904-9mta0aem	358	35	.	.	.
cord-322904-9mta0aem	359	1	SV40	SV40	NNP
cord-322904-9mta0aem	359	2	VP1	VP1	NNP
cord-322904-9mta0aem	359	3	possesses	possess	VBZ
cord-322904-9mta0aem	359	4	quite	quite	RB
cord-322904-9mta0aem	359	5	narrow	narrow	JJ
cord-322904-9mta0aem	359	6	specificity	specificity	NN
cord-322904-9mta0aem	359	7	for	for	IN
cord-322904-9mta0aem	359	8	the	the	DT
cord-322904-9mta0aem	359	9	oligosaccharide	oligosaccharide	JJ
cord-322904-9mta0aem	359	10	part	part	NN
cord-322904-9mta0aem	359	11	of	of	IN
cord-322904-9mta0aem	359	12	the	the	DT
cord-322904-9mta0aem	359	13	ganglioside	ganglioside	NN
cord-322904-9mta0aem	359	14	GM1	GM1	NNP
cord-322904-9mta0aem	359	15	,	,	,
cord-322904-9mta0aem	359	16	which	which	WDT
cord-322904-9mta0aem	359	17	is	be	VBZ
cord-322904-9mta0aem	359	18	a	a	DT
cord-322904-9mta0aem	359	19	branched	branched	JJ
cord-322904-9mta0aem	359	20	compound	compound	NN
cord-322904-9mta0aem	359	21	of	of	IN
cord-322904-9mta0aem	359	22	the	the	DT
cord-322904-9mta0aem	359	23	following	following	JJ
cord-322904-9mta0aem	359	24	structure	structure	NN
cord-322904-9mta0aem	359	25	:	:	:
cord-322904-9mta0aem	359	26	Gal	gal	NN
cord-322904-9mta0aem	359	27	-	-	HYPH
cord-322904-9mta0aem	359	28	β1,3-GalNAc	β1,3-galnac	XX
cord-322904-9mta0aem	359	29	-	-	HYPH
cord-322904-9mta0aem	359	30	β1,4-[NeuNAc	β1,4-[neunac	XX
cord-322904-9mta0aem	360	1	-α2,3-]-Gal	-α2,3-]-Gal	:
cord-322904-9mta0aem	360	2	-	-	HYPH
cord-322904-9mta0aem	360	3	β1,4-Glc	β1,4-glc	ADD
cord-322904-9mta0aem	360	4	.	.	.
cord-322904-9mta0aem	361	1	While	while	IN
cord-322904-9mta0aem	361	2	SV40	SV40	NNP
cord-322904-9mta0aem	361	3	still	still	RB
cord-322904-9mta0aem	361	4	binds	bind	VBZ
cord-322904-9mta0aem	361	5	the	the	DT
cord-322904-9mta0aem	361	6	same	same	JJ
cord-322904-9mta0aem	361	7	compound	compound	NN
cord-322904-9mta0aem	361	8	with	with	IN
cord-322904-9mta0aem	361	9	NeuNGc	neungc	NN
cord-322904-9mta0aem	361	10	substituted	substitute	VBN
cord-322904-9mta0aem	361	11	for	for	IN
cord-322904-9mta0aem	361	12	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	361	13	,	,	,
cord-322904-9mta0aem	361	14	binding	bind	VBG
cord-322904-9mta0aem	361	15	is	be	VBZ
cord-322904-9mta0aem	361	16	abolished	abolish	VBN
cord-322904-9mta0aem	361	17	if	if	IN
cord-322904-9mta0aem	361	18	one	one	CD
cord-322904-9mta0aem	361	19	of	of	IN
cord-322904-9mta0aem	361	20	the	the	DT
cord-322904-9mta0aem	361	21	terminal	terminal	JJ
cord-322904-9mta0aem	361	22	sugars	sugar	NNS
cord-322904-9mta0aem	361	23	,	,	,
cord-322904-9mta0aem	361	24	i.e.	i.e.	FW
cord-322904-9mta0aem	361	25	Gal	gal	NN
cord-322904-9mta0aem	361	26	or	or	CC
cord-322904-9mta0aem	361	27	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	361	28	,	,	,
cord-322904-9mta0aem	361	29	are	be	VBP
cord-322904-9mta0aem	361	30	removed	remove	VBN
cord-322904-9mta0aem	361	31	or	or	CC
cord-322904-9mta0aem	361	32	if	if	IN
cord-322904-9mta0aem	361	33	one	one	CD
cord-322904-9mta0aem	361	34	of	of	IN
cord-322904-9mta0aem	361	35	them	-PRON-	PRP
cord-322904-9mta0aem	361	36	bears	bear	VBZ
cord-322904-9mta0aem	361	37	an	an	DT
cord-322904-9mta0aem	361	38	additional	additional	JJ
cord-322904-9mta0aem	361	39	sugar	sugar	NN
cord-322904-9mta0aem	361	40	moiety	moiety	NN
cord-322904-9mta0aem	361	41	(	(	-LRB-
cord-322904-9mta0aem	361	42	Campanero	Campanero	NNP
cord-322904-9mta0aem	361	43	-	-	HYPH
cord-322904-9mta0aem	361	44	Rhodes	Rhodes	NNP
cord-322904-9mta0aem	361	45	et	et	NNP
cord-322904-9mta0aem	361	46	al	al	NNP
cord-322904-9mta0aem	361	47	.	.	NNP
cord-322904-9mta0aem	361	48	,	,	,
cord-322904-9mta0aem	361	49	2007	2007	CD
cord-322904-9mta0aem	361	50	;	;	.
cord-322904-9mta0aem	362	1	Neu	Neu	NNP
cord-322904-9mta0aem	362	2	et	et	NNP
cord-322904-9mta0aem	362	3	al	al	NNP
cord-322904-9mta0aem	362	4	.	.	NNP
cord-322904-9mta0aem	362	5	,	,	,
cord-322904-9mta0aem	362	6	2008	2008	CD
cord-322904-9mta0aem	362	7	)	)	-RRB-
cord-322904-9mta0aem	362	8	.	.	.
cord-322904-9mta0aem	363	1	Both	both	DT
cord-322904-9mta0aem	363	2	the	the	DT
cord-322904-9mta0aem	363	3	Gal	Gal	NNP
cord-322904-9mta0aem	363	4	-	-	HYPH
cord-322904-9mta0aem	363	5	β1,3-GalNAc	β1,3-galnac	XX
cord-322904-9mta0aem	363	6	and	and	CC
cord-322904-9mta0aem	363	7	NeuNAc	neunac	JJ
cord-322904-9mta0aem	363	8	branches	branch	NNS
cord-322904-9mta0aem	363	9	directly	directly	RB
cord-322904-9mta0aem	363	10	contact	contact	VBP
cord-322904-9mta0aem	363	11	the	the	DT
cord-322904-9mta0aem	363	12	protein	protein	NN
cord-322904-9mta0aem	363	13	,	,	,
cord-322904-9mta0aem	363	14	providing	provide	VBG
cord-322904-9mta0aem	363	15	binding	bind	VBG
cord-322904-9mta0aem	363	16	affinity	affinity	NN
cord-322904-9mta0aem	363	17	.	.	.
cord-322904-9mta0aem	364	1	The	the	DT
cord-322904-9mta0aem	364	2	core	core	NN
cord-322904-9mta0aem	364	3	structure	structure	NN
cord-322904-9mta0aem	364	4	of	of	IN
cord-322904-9mta0aem	364	5	GM1	GM1	NNP
cord-322904-9mta0aem	364	6	,	,	,
cord-322904-9mta0aem	364	7	i.e.	i.e.	FW
cord-322904-9mta0aem	364	8	the	the	DT
cord-322904-9mta0aem	364	9	branching	branch	VBG
cord-322904-9mta0aem	364	10	Gal	Gal	NNP
cord-322904-9mta0aem	364	11	with	with	IN
cord-322904-9mta0aem	364	12	GalNAc	GalNAc	NNP
cord-322904-9mta0aem	364	13	and	and	CC
cord-322904-9mta0aem	364	14	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	364	15	attached	attach	VBD
cord-322904-9mta0aem	364	16	to	to	IN
cord-322904-9mta0aem	364	17	neighboring	neighboring	NN
cord-322904-9mta0aem	364	18	atoms	atom	NNS
cord-322904-9mta0aem	364	19	is	be	VBZ
cord-322904-9mta0aem	364	20	sterically	sterically	RB
cord-322904-9mta0aem	364	21	constrained	constrain	VBN
cord-322904-9mta0aem	364	22	as	as	IN
cord-322904-9mta0aem	364	23	clashes	clash	NNS
cord-322904-9mta0aem	364	24	between	between	IN
cord-322904-9mta0aem	364	25	GalNAc	GalNAc	NNP
cord-322904-9mta0aem	364	26	and	and	CC
cord-322904-9mta0aem	364	27	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	364	28	could	could	MD
cord-322904-9mta0aem	364	29	occur	occur	VB
cord-322904-9mta0aem	364	30	in	in	IN
cord-322904-9mta0aem	364	31	many	many	JJ
cord-322904-9mta0aem	364	32	conformations	conformation	NNS
cord-322904-9mta0aem	364	33	of	of	IN
cord-322904-9mta0aem	364	34	the	the	DT
cord-322904-9mta0aem	364	35	glycosidic	glycosidic	JJ
cord-322904-9mta0aem	364	36	linkages	linkage	NNS
cord-322904-9mta0aem	364	37	.	.	.
cord-322904-9mta0aem	365	1	The	the	DT
cord-322904-9mta0aem	365	2	moiety	moiety	NN
cord-322904-9mta0aem	365	3	adopts	adopt	VBZ
cord-322904-9mta0aem	365	4	one	one	CD
cord-322904-9mta0aem	365	5	dominant	dominant	JJ
cord-322904-9mta0aem	365	6	conformation	conformation	NN
cord-322904-9mta0aem	365	7	in	in	IN
cord-322904-9mta0aem	365	8	solution	solution	NN
cord-322904-9mta0aem	365	9	(	(	-LRB-
cord-322904-9mta0aem	365	10	Poppe	Poppe	NNP
cord-322904-9mta0aem	365	11	et	et	NNP
cord-322904-9mta0aem	365	12	al	al	NNP
cord-322904-9mta0aem	365	13	.	.	NNP
cord-322904-9mta0aem	365	14	,	,	,
cord-322904-9mta0aem	365	15	1994	1994	CD
cord-322904-9mta0aem	365	16	)	)	-RRB-
cord-322904-9mta0aem	365	17	,	,	,
cord-322904-9mta0aem	365	18	which	which	WDT
cord-322904-9mta0aem	365	19	is	be	VBZ
cord-322904-9mta0aem	365	20	bound	bind	VBN
cord-322904-9mta0aem	365	21	by	by	IN
cord-322904-9mta0aem	365	22	SV40	SV40	NNP
cord-322904-9mta0aem	365	23	VP1	VP1	NNP
cord-322904-9mta0aem	365	24	.	.	.
cord-322904-9mta0aem	366	1	Specificity	specificity	NN
cord-322904-9mta0aem	366	2	therefore	therefore	RB
cord-322904-9mta0aem	366	3	arises	arise	VBZ
cord-322904-9mta0aem	366	4	from	from	IN
cord-322904-9mta0aem	366	5	SV40	SV40	NNP
cord-322904-9mta0aem	366	6	recognizing	recognize	VBG
cord-322904-9mta0aem	366	7	the	the	DT
cord-322904-9mta0aem	366	8	correct	correct	JJ
cord-322904-9mta0aem	366	9	placement	placement	NN
cord-322904-9mta0aem	366	10	of	of	IN
cord-322904-9mta0aem	366	11	the	the	DT
cord-322904-9mta0aem	366	12	two	two	CD
cord-322904-9mta0aem	366	13	binding	bind	VBG
cord-322904-9mta0aem	366	14	arms	arm	NNS
cord-322904-9mta0aem	366	15	by	by	IN
cord-322904-9mta0aem	366	16	a	a	DT
cord-322904-9mta0aem	366	17	rigid	rigid	JJ
cord-322904-9mta0aem	366	18	spacer	spacer	NN
cord-322904-9mta0aem	366	19	.	.	.
cord-322904-9mta0aem	367	1	Different	different	JJ
cord-322904-9mta0aem	367	2	strains	strain	NNS
cord-322904-9mta0aem	367	3	of	of	IN
cord-322904-9mta0aem	367	4	Influenza	Influenza	NNP
cord-322904-9mta0aem	367	5	A	a	DT
cord-322904-9mta0aem	367	6	virus	virus	NN
cord-322904-9mta0aem	367	7	infect	infect	VBP
cord-322904-9mta0aem	367	8	different	different	JJ
cord-322904-9mta0aem	367	9	species	specie	NNS
cord-322904-9mta0aem	367	10	because	because	IN
cord-322904-9mta0aem	367	11	their	-PRON-	PRP$
cord-322904-9mta0aem	367	12	HA	HA	NNP
cord-322904-9mta0aem	367	13	molecules	molecule	NNS
cord-322904-9mta0aem	367	14	bind	bind	VBP
cord-322904-9mta0aem	367	15	sialic	sialic	NN
cord-322904-9mta0aem	367	16	acid	acid	NN
cord-322904-9mta0aem	367	17	in	in	IN
cord-322904-9mta0aem	367	18	different	different	JJ
cord-322904-9mta0aem	367	19	contexts	context	NNS
cord-322904-9mta0aem	367	20	.	.	.
cord-322904-9mta0aem	368	1	The	the	DT
cord-322904-9mta0aem	368	2	adaptation	adaptation	NN
cord-322904-9mta0aem	368	3	of	of	IN
cord-322904-9mta0aem	368	4	avian	avian	NN
cord-322904-9mta0aem	368	5	HAs	have	VBZ
cord-322904-9mta0aem	368	6	to	to	IN
cord-322904-9mta0aem	368	7	human	human	JJ
cord-322904-9mta0aem	368	8	hosts	host	NNS
cord-322904-9mta0aem	368	9	occurs	occur	VBZ
cord-322904-9mta0aem	368	10	by	by	IN
cord-322904-9mta0aem	368	11	a	a	DT
cord-322904-9mta0aem	368	12	switch	switch	NN
cord-322904-9mta0aem	368	13	in	in	IN
cord-322904-9mta0aem	368	14	binding	bind	VBG
cord-322904-9mta0aem	368	15	specificity	specificity	NN
cord-322904-9mta0aem	368	16	from	from	IN
cord-322904-9mta0aem	368	17	avian	avian	JJ
cord-322904-9mta0aem	368	18	-	-	HYPH
cord-322904-9mta0aem	368	19	like	like	JJ
cord-322904-9mta0aem	368	20	α2,3-sialylated	α2,3-sialylated	NNP
cord-322904-9mta0aem	368	21	glycans	glycan	NNS
cord-322904-9mta0aem	368	22	to	to	IN
cord-322904-9mta0aem	368	23	the	the	DT
cord-322904-9mta0aem	368	24	longer	long	JJR
cord-322904-9mta0aem	368	25	α2,6-sialylated	α2,6-sialylated	CD
cord-322904-9mta0aem	368	26	glycans	glycan	NNS
cord-322904-9mta0aem	368	27	that	that	WDT
cord-322904-9mta0aem	368	28	are	be	VBP
cord-322904-9mta0aem	368	29	present	present	JJ
cord-322904-9mta0aem	368	30	in	in	IN
cord-322904-9mta0aem	368	31	the	the	DT
cord-322904-9mta0aem	368	32	upper	upper	JJ
cord-322904-9mta0aem	368	33	respiratory	respiratory	JJ
cord-322904-9mta0aem	368	34	tract	tract	NN
cord-322904-9mta0aem	368	35	epithelia	epithelium	NNS
cord-322904-9mta0aem	368	36	of	of	IN
cord-322904-9mta0aem	368	37	humans	human	NNS
cord-322904-9mta0aem	369	1	(	(	-LRB-
cord-322904-9mta0aem	369	2	Russell	Russell	NNP
cord-322904-9mta0aem	369	3	et	et	NNP
cord-322904-9mta0aem	369	4	al	al	NNP
cord-322904-9mta0aem	369	5	.	.	NNP
cord-322904-9mta0aem	369	6	,	,	,
cord-322904-9mta0aem	369	7	2006	2006	CD
cord-322904-9mta0aem	369	8	;	;	:
cord-322904-9mta0aem	369	9	Skehel	Skehel	NNP
cord-322904-9mta0aem	369	10	and	and	CC
cord-322904-9mta0aem	369	11	Wiley	Wiley	NNP
cord-322904-9mta0aem	369	12	,	,	,
cord-322904-9mta0aem	369	13	2000	2000	CD
cord-322904-9mta0aem	369	14	;	;	:
cord-322904-9mta0aem	370	1	Stevens	Stevens	NNP
cord-322904-9mta0aem	370	2	et	et	NNP
cord-322904-9mta0aem	370	3	al	al	NNP
cord-322904-9mta0aem	370	4	.	.	NNP
cord-322904-9mta0aem	370	5	,	,	,
cord-322904-9mta0aem	370	6	2006	2006	CD
cord-322904-9mta0aem	370	7	;	;	:
cord-322904-9mta0aem	370	8	van	van	NNP
cord-322904-9mta0aem	370	9	Riel	Riel	NNP
cord-322904-9mta0aem	370	10	et	et	FW
cord-322904-9mta0aem	370	11	al	al	NNP
cord-322904-9mta0aem	370	12	.	.	NNP
cord-322904-9mta0aem	370	13	,	,	,
cord-322904-9mta0aem	370	14	2007	2007	CD
cord-322904-9mta0aem	370	15	)	)	-RRB-
cord-322904-9mta0aem	370	16	.	.	.
cord-322904-9mta0aem	371	1	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	371	2	is	be	VBZ
cord-322904-9mta0aem	371	3	bound	bind	VBN
cord-322904-9mta0aem	371	4	in	in	IN
cord-322904-9mta0aem	371	5	the	the	DT
cord-322904-9mta0aem	371	6	same	same	JJ
cord-322904-9mta0aem	371	7	orientation	orientation	NN
cord-322904-9mta0aem	371	8	and	and	CC
cord-322904-9mta0aem	371	9	by	by	IN
cord-322904-9mta0aem	371	10	the	the	DT
cord-322904-9mta0aem	371	11	same	same	JJ
cord-322904-9mta0aem	371	12	residues	residue	NNS
cord-322904-9mta0aem	371	13	of	of	IN
cord-322904-9mta0aem	371	14	both	both	DT
cord-322904-9mta0aem	371	15	avian	avian	JJ
cord-322904-9mta0aem	371	16	and	and	CC
cord-322904-9mta0aem	371	17	human	human	NN
cord-322904-9mta0aem	371	18	HAs	have	VBZ
cord-322904-9mta0aem	371	19	so	so	IN
cord-322904-9mta0aem	371	20	that	that	DT
cord-322904-9mta0aem	371	21	specificity	specificity	NN
cord-322904-9mta0aem	371	22	is	be	VBZ
cord-322904-9mta0aem	371	23	conferred	confer	VBN
cord-322904-9mta0aem	371	24	by	by	IN
cord-322904-9mta0aem	371	25	the	the	DT
cord-322904-9mta0aem	371	26	residues	residue	NNS
cord-322904-9mta0aem	371	27	in	in	IN
cord-322904-9mta0aem	371	28	contact	contact	NN
cord-322904-9mta0aem	371	29	with	with	IN
cord-322904-9mta0aem	371	30	additional	additional	JJ
cord-322904-9mta0aem	371	31	monosaccharides	monosaccharide	NNS
cord-322904-9mta0aem	371	32	.	.	.
cord-322904-9mta0aem	372	1	Recent	recent	JJ
cord-322904-9mta0aem	372	2	data	datum	NNS
cord-322904-9mta0aem	372	3	indicate	indicate	VBP
cord-322904-9mta0aem	372	4	that	that	IN
cord-322904-9mta0aem	372	5	the	the	DT
cord-322904-9mta0aem	372	6	different	different	JJ
cord-322904-9mta0aem	372	7	glycan	glycan	NN
cord-322904-9mta0aem	372	8	types	type	NNS
cord-322904-9mta0aem	372	9	are	be	VBP
cord-322904-9mta0aem	372	10	not	not	RB
cord-322904-9mta0aem	372	11	discriminated	discriminate	VBN
cord-322904-9mta0aem	372	12	by	by	IN
cord-322904-9mta0aem	372	13	contacts	contact	NNS
cord-322904-9mta0aem	372	14	with	with	IN
cord-322904-9mta0aem	372	15	the	the	DT
cord-322904-9mta0aem	372	16	sugar	sugar	NN
cord-322904-9mta0aem	372	17	residue	residue	NN
cord-322904-9mta0aem	372	18	to	to	TO
cord-322904-9mta0aem	372	19	which	which	WDT
cord-322904-9mta0aem	372	20	the	the	DT
cord-322904-9mta0aem	372	21	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	372	22	is	be	VBZ
cord-322904-9mta0aem	372	23	linked	link	VBN
cord-322904-9mta0aem	372	24	,	,	,
cord-322904-9mta0aem	372	25	but	but	CC
cord-322904-9mta0aem	372	26	that	that	IN
cord-322904-9mta0aem	372	27	the	the	DT
cord-322904-9mta0aem	372	28	different	different	JJ
cord-322904-9mta0aem	372	29	overall	overall	JJ
cord-322904-9mta0aem	372	30	topology	topology	NN
cord-322904-9mta0aem	372	31	of	of	IN
cord-322904-9mta0aem	372	32	the	the	DT
cord-322904-9mta0aem	372	33	glycans	glycan	NNS
cord-322904-9mta0aem	372	34	is	be	VBZ
cord-322904-9mta0aem	372	35	recognized	recognize	VBN
cord-322904-9mta0aem	372	36	(	(	-LRB-
cord-322904-9mta0aem	372	37	Chandrasekaran	Chandrasekaran	NNP
cord-322904-9mta0aem	372	38	et	et	NNP
cord-322904-9mta0aem	372	39	al	al	NNP
cord-322904-9mta0aem	372	40	.	.	NNP
cord-322904-9mta0aem	372	41	,	,	,
cord-322904-9mta0aem	372	42	2008	2008	CD
cord-322904-9mta0aem	372	43	)	)	-RRB-
cord-322904-9mta0aem	372	44	.	.	.
cord-322904-9mta0aem	373	1	Given	give	VBN
cord-322904-9mta0aem	373	2	the	the	DT
cord-322904-9mta0aem	373	3	preferred	preferred	JJ
cord-322904-9mta0aem	373	4	torsion	torsion	NN
cord-322904-9mta0aem	373	5	angles	angle	NNS
cord-322904-9mta0aem	373	6	of	of	IN
cord-322904-9mta0aem	373	7	the	the	DT
cord-322904-9mta0aem	373	8	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	373	9	-	-	HYPH
cord-322904-9mta0aem	373	10	α2,3-Gal	α2,3-gal	CD
cord-322904-9mta0aem	373	11	-	-	HYPH
cord-322904-9mta0aem	373	12	β1,3/4-GlcNAc	β1,3/4-glcnac	NN
cord-322904-9mta0aem	373	13	motif	motif	NN
cord-322904-9mta0aem	373	14	typical	typical	JJ
cord-322904-9mta0aem	373	15	of	of	IN
cord-322904-9mta0aem	373	16	the	the	DT
cord-322904-9mta0aem	373	17	recognized	recognize	VBN
cord-322904-9mta0aem	373	18	α2,3-linked	α2,3-linked	IN
cord-322904-9mta0aem	373	19	glycans	glycan	NNS
cord-322904-9mta0aem	373	20	,	,	,
cord-322904-9mta0aem	373	21	the	the	DT
cord-322904-9mta0aem	373	22	Gal	Gal	NNP
cord-322904-9mta0aem	373	23	-	-	HYPH
cord-322904-9mta0aem	373	24	β1,3/4-GalNAc	β1,3/4-GalNAc	NNP
cord-322904-9mta0aem	373	25	part	part	NN
cord-322904-9mta0aem	373	26	is	be	VBZ
cord-322904-9mta0aem	373	27	fairly	fairly	RB
cord-322904-9mta0aem	373	28	linear	linear	JJ
cord-322904-9mta0aem	373	29	and	and	CC
cord-322904-9mta0aem	373	30	can	can	MD
cord-322904-9mta0aem	373	31	occupy	occupy	VB
cord-322904-9mta0aem	373	32	the	the	DT
cord-322904-9mta0aem	373	33	space	space	NN
cord-322904-9mta0aem	373	34	delineated	delineate	VBN
cord-322904-9mta0aem	373	35	by	by	IN
cord-322904-9mta0aem	373	36	a	a	DT
cord-322904-9mta0aem	373	37	cone	cone	NN
cord-322904-9mta0aem	373	38	with	with	IN
cord-322904-9mta0aem	373	39	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	373	40	at	at	IN
cord-322904-9mta0aem	373	41	its	-PRON-	PRP$
cord-322904-9mta0aem	373	42	tip	tip	NN
cord-322904-9mta0aem	373	43	.	.	.
cord-322904-9mta0aem	374	1	Sugar	sugar	NN
cord-322904-9mta0aem	374	2	moieties	moiety	NNS
cord-322904-9mta0aem	374	3	farther	farther	RB
cord-322904-9mta0aem	374	4	away	away	RB
cord-322904-9mta0aem	374	5	from	from	IN
cord-322904-9mta0aem	374	6	the	the	DT
cord-322904-9mta0aem	374	7	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	374	8	mostly	mostly	RB
cord-322904-9mta0aem	374	9	do	do	VBP
cord-322904-9mta0aem	374	10	not	not	RB
cord-322904-9mta0aem	374	11	interact	interact	VB
cord-322904-9mta0aem	374	12	with	with	IN
cord-322904-9mta0aem	374	13	the	the	DT
cord-322904-9mta0aem	374	14	protein	protein	NN
cord-322904-9mta0aem	374	15	in	in	IN
cord-322904-9mta0aem	374	16	this	this	DT
cord-322904-9mta0aem	374	17	conformation	conformation	NN
cord-322904-9mta0aem	374	18	.	.	.
cord-322904-9mta0aem	375	1	The	the	DT
cord-322904-9mta0aem	375	2	glycans	glycan	NNS
cord-322904-9mta0aem	375	3	containing	contain	VBG
cord-322904-9mta0aem	375	4	α2,6-linked	α2,6-linked	CD
cord-322904-9mta0aem	375	5	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	375	6	,	,	,
cord-322904-9mta0aem	375	7	for	for	IN
cord-322904-9mta0aem	375	8	which	which	WDT
cord-322904-9mta0aem	375	9	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	375	10	-	-	HYPH
cord-322904-9mta0aem	375	11	α2,6-Gal	α2,6-gal	XX
cord-322904-9mta0aem	375	12	-	-	HYPH
cord-322904-9mta0aem	375	13	β1,4-GlcNAc	β1,4-glcnac	NN
cord-322904-9mta0aem	375	14	is	be	VBZ
cord-322904-9mta0aem	375	15	typical	typical	JJ
cord-322904-9mta0aem	375	16	,	,	,
cord-322904-9mta0aem	375	17	can	can	MD
cord-322904-9mta0aem	375	18	also	also	RB
cord-322904-9mta0aem	375	19	adopt	adopt	VB
cord-322904-9mta0aem	375	20	this	this	DT
cord-322904-9mta0aem	375	21	coneshaped	coneshape	VBN
cord-322904-9mta0aem	375	22	topology	topology	NN
cord-322904-9mta0aem	375	23	.	.	.
cord-322904-9mta0aem	376	1	However	however	RB
cord-322904-9mta0aem	376	2	,	,	,
cord-322904-9mta0aem	376	3	these	these	DT
cord-322904-9mta0aem	376	4	also	also	RB
cord-322904-9mta0aem	376	5	sample	sample	VBP
cord-322904-9mta0aem	376	6	a	a	DT
cord-322904-9mta0aem	376	7	topology	topology	NN
cord-322904-9mta0aem	376	8	,	,	,
cord-322904-9mta0aem	376	9	in	in	IN
cord-322904-9mta0aem	376	10	which	which	WDT
cord-322904-9mta0aem	376	11	the	the	DT
cord-322904-9mta0aem	376	12	Gal	Gal	NNP
cord-322904-9mta0aem	376	13	is	be	VBZ
cord-322904-9mta0aem	376	14	relatively	relatively	RB
cord-322904-9mta0aem	376	15	fixed	fix	VBN
cord-322904-9mta0aem	376	16	with	with	IN
cord-322904-9mta0aem	376	17	respect	respect	NN
cord-322904-9mta0aem	376	18	to	to	IN
cord-322904-9mta0aem	376	19	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	376	20	and	and	CC
cord-322904-9mta0aem	376	21	there	there	EX
cord-322904-9mta0aem	376	22	is	be	VBZ
cord-322904-9mta0aem	376	23	a	a	DT
cord-322904-9mta0aem	376	24	kink	kink	NN
cord-322904-9mta0aem	376	25	at	at	IN
cord-322904-9mta0aem	376	26	the	the	DT
cord-322904-9mta0aem	376	27	Gal	Gal	NNP
cord-322904-9mta0aem	376	28	position	position	NN
cord-322904-9mta0aem	376	29	,	,	,
cord-322904-9mta0aem	376	30	forcing	force	VBG
cord-322904-9mta0aem	376	31	the	the	DT
cord-322904-9mta0aem	376	32	GlcNAc	GlcNAc	NNP
cord-322904-9mta0aem	376	33	and	and	CC
cord-322904-9mta0aem	376	34	subsequent	subsequent	JJ
cord-322904-9mta0aem	376	35	sugars	sugar	NNS
cord-322904-9mta0aem	376	36	to	to	TO
cord-322904-9mta0aem	376	37	point	point	VB
cord-322904-9mta0aem	376	38	back	back	RB
cord-322904-9mta0aem	376	39	towards	towards	IN
cord-322904-9mta0aem	376	40	the	the	DT
cord-322904-9mta0aem	376	41	protein	protein	NN
cord-322904-9mta0aem	376	42	.	.	.
cord-322904-9mta0aem	377	1	The	the	DT
cord-322904-9mta0aem	377	2	space	space	NN
cord-322904-9mta0aem	377	3	that	that	WDT
cord-322904-9mta0aem	377	4	can	can	MD
cord-322904-9mta0aem	377	5	be	be	VB
cord-322904-9mta0aem	377	6	sampled	sample	VBN
cord-322904-9mta0aem	377	7	by	by	IN
cord-322904-9mta0aem	377	8	the	the	DT
cord-322904-9mta0aem	377	9	glycan	glycan	NN
cord-322904-9mta0aem	377	10	therefore	therefore	RB
cord-322904-9mta0aem	377	11	resembles	resemble	VBZ
cord-322904-9mta0aem	377	12	an	an	DT
cord-322904-9mta0aem	377	13	umbrella	umbrella	NN
cord-322904-9mta0aem	377	14	,	,	,
cord-322904-9mta0aem	377	15	with	with	IN
cord-322904-9mta0aem	377	16	NeuNAc	NeuNAc	NNP
cord-322904-9mta0aem	377	17	-	-	HYPH
cord-322904-9mta0aem	377	18	α2,6-Gal	α2,6-gal	NN
cord-322904-9mta0aem	377	19	as	as	IN
cord-322904-9mta0aem	377	20	the	the	DT
cord-322904-9mta0aem	377	21	stick	stick	NN
cord-322904-9mta0aem	377	22	and	and	CC
cord-322904-9mta0aem	377	23	the	the	DT
cord-322904-9mta0aem	377	24	rest	rest	NN
cord-322904-9mta0aem	377	25	of	of	IN
cord-322904-9mta0aem	377	26	the	the	DT
cord-322904-9mta0aem	377	27	glycan	glycan	NN
cord-322904-9mta0aem	377	28	as	as	IN
cord-322904-9mta0aem	377	29	the	the	DT
cord-322904-9mta0aem	377	30	umbrella	umbrella	NN
cord-322904-9mta0aem	377	31	.	.	.
cord-322904-9mta0aem	378	1	For	for	IN
cord-322904-9mta0aem	378	2	α2,6-linked	α2,6-linked	CD
cord-322904-9mta0aem	378	3	trisaccharides	trisaccharide	NNS
cord-322904-9mta0aem	378	4	that	that	WDT
cord-322904-9mta0aem	378	5	can	can	MD
cord-322904-9mta0aem	378	6	sample	sample	VB
cord-322904-9mta0aem	378	7	both	both	DT
cord-322904-9mta0aem	378	8	cone	cone	NN
cord-322904-9mta0aem	378	9	-	-	HYPH
cord-322904-9mta0aem	378	10	and	and	CC
cord-322904-9mta0aem	378	11	umbrella	umbrella	NN
cord-322904-9mta0aem	378	12	-	-	HYPH
cord-322904-9mta0aem	378	13	shaped	shape	VBN
cord-322904-9mta0aem	378	14	topologies	topology	NNS
cord-322904-9mta0aem	378	15	,	,	,
cord-322904-9mta0aem	378	16	the	the	DT
cord-322904-9mta0aem	378	17	cone	cone	NN
cord-322904-9mta0aem	378	18	-	-	HYPH
cord-322904-9mta0aem	378	19	shaped	shape	VBN
cord-322904-9mta0aem	378	20	one	one	CD
cord-322904-9mta0aem	378	21	is	be	VBZ
cord-322904-9mta0aem	378	22	preferred	prefer	VBN
cord-322904-9mta0aem	378	23	.	.	.
cord-322904-9mta0aem	379	1	However	however	RB
cord-322904-9mta0aem	379	2	,	,	,
cord-322904-9mta0aem	379	3	the	the	DT
cord-322904-9mta0aem	379	4	longer	long	RBR
cord-322904-9mta0aem	379	5	α2,6-linked	α2,6-linke	VBN
cord-322904-9mta0aem	379	6	glycans	glycan	NNS
cord-322904-9mta0aem	379	7	that	that	WDT
cord-322904-9mta0aem	379	8	confer	confer	VBP
cord-322904-9mta0aem	379	9	infectivity	infectivity	NN
cord-322904-9mta0aem	379	10	in	in	IN
cord-322904-9mta0aem	379	11	humans	human	NNS
cord-322904-9mta0aem	379	12	prefer	prefer	VBP
cord-322904-9mta0aem	379	13	the	the	DT
cord-322904-9mta0aem	379	14	umbrella	umbrella	NN
cord-322904-9mta0aem	379	15	-	-	HYPH
cord-322904-9mta0aem	379	16	shaped	shape	VBN
cord-322904-9mta0aem	379	17	topologies	topology	NNS
cord-322904-9mta0aem	379	18	,	,	,
cord-322904-9mta0aem	379	19	leading	lead	VBG
cord-322904-9mta0aem	379	20	to	to	IN
cord-322904-9mta0aem	379	21	additional	additional	JJ
cord-322904-9mta0aem	379	22	contacts	contact	NNS
cord-322904-9mta0aem	379	23	with	with	IN
cord-322904-9mta0aem	379	24	the	the	DT
cord-322904-9mta0aem	379	25	protein	protein	NN
cord-322904-9mta0aem	379	26	.	.	.
cord-322904-9mta0aem	380	1	If	if	IN
cord-322904-9mta0aem	380	2	the	the	DT
cord-322904-9mta0aem	380	3	HA	HA	NNP
cord-322904-9mta0aem	380	4	of	of	IN
cord-322904-9mta0aem	380	5	an	an	DT
cord-322904-9mta0aem	380	6	influenza	influenza	NN
cord-322904-9mta0aem	380	7	strain	strain	NN
cord-322904-9mta0aem	380	8	can	can	MD
cord-322904-9mta0aem	380	9	not	not	RB
cord-322904-9mta0aem	380	10	accommodate	accommodate	VB
cord-322904-9mta0aem	380	11	these	these	DT
cord-322904-9mta0aem	380	12	long	long	JJ
cord-322904-9mta0aem	380	13	,	,	,
cord-322904-9mta0aem	380	14	umbrella	umbrella	NN
cord-322904-9mta0aem	380	15	-	-	HYPH
cord-322904-9mta0aem	380	16	shaped	shape	VBN
cord-322904-9mta0aem	380	17	α2,6-linked	α2,6-linked	NNP
cord-322904-9mta0aem	380	18	glycans	glycan	NNS
cord-322904-9mta0aem	380	19	,	,	,
cord-322904-9mta0aem	380	20	it	-PRON-	PRP
cord-322904-9mta0aem	380	21	can	can	MD
cord-322904-9mta0aem	380	22	not	not	RB
cord-322904-9mta0aem	380	23	spread	spread	VB
cord-322904-9mta0aem	380	24	in	in	IN
cord-322904-9mta0aem	380	25	humans	human	NNS
cord-322904-9mta0aem	380	26	(	(	-LRB-
cord-322904-9mta0aem	380	27	Chandrasekaran	Chandrasekaran	NNP
cord-322904-9mta0aem	380	28	et	et	NNP
cord-322904-9mta0aem	380	29	al	al	NNP
cord-322904-9mta0aem	380	30	.	.	NNP
cord-322904-9mta0aem	380	31	,	,	,
cord-322904-9mta0aem	380	32	2008	2008	CD
cord-322904-9mta0aem	380	33	)	)	-RRB-
cord-322904-9mta0aem	380	34	.	.	.
cord-322904-9mta0aem	381	1	Several	several	JJ
cord-322904-9mta0aem	381	2	of	of	IN
cord-322904-9mta0aem	381	3	the	the	DT
cord-322904-9mta0aem	381	4	structural	structural	JJ
cord-322904-9mta0aem	381	5	and	and	CC
cord-322904-9mta0aem	381	6	functional	functional	JJ
cord-322904-9mta0aem	381	7	studies	study	NNS
cord-322904-9mta0aem	381	8	described	describe	VBN
cord-322904-9mta0aem	381	9	above	above	RB
cord-322904-9mta0aem	381	10	required	require	VBD
cord-322904-9mta0aem	381	11	the	the	DT
cord-322904-9mta0aem	381	12	use	use	NN
cord-322904-9mta0aem	381	13	of	of	IN
cord-322904-9mta0aem	381	14	correct	correct	JJ
cord-322904-9mta0aem	381	15	ligands	ligand	NNS
cord-322904-9mta0aem	381	16	.	.	.
cord-322904-9mta0aem	382	1	The	the	DT
cord-322904-9mta0aem	382	2	use	use	NN
cord-322904-9mta0aem	382	3	of	of	IN
cord-322904-9mta0aem	382	4	model	model	NN
cord-322904-9mta0aem	382	5	glycans	glycan	NNS
cord-322904-9mta0aem	382	6	such	such	JJ
cord-322904-9mta0aem	382	7	as	as	IN
cord-322904-9mta0aem	382	8	α2,6-linked	α2,6-linked	CD
cord-322904-9mta0aem	382	9	sialyllactose	sialyllactose	NNP
cord-322904-9mta0aem	382	10	would	would	MD
cord-322904-9mta0aem	382	11	not	not	RB
cord-322904-9mta0aem	382	12	have	have	VB
cord-322904-9mta0aem	382	13	revealed	reveal	VBN
cord-322904-9mta0aem	382	14	the	the	DT
cord-322904-9mta0aem	382	15	difference	difference	NN
cord-322904-9mta0aem	382	16	in	in	IN
cord-322904-9mta0aem	382	17	topology	topology	NN
cord-322904-9mta0aem	382	18	that	that	WDT
cord-322904-9mta0aem	382	19	is	be	VBZ
cord-322904-9mta0aem	382	20	crucial	crucial	JJ
cord-322904-9mta0aem	382	21	for	for	IN
cord-322904-9mta0aem	382	22	glycan	glycan	NN
cord-322904-9mta0aem	382	23	recognition	recognition	NN
cord-322904-9mta0aem	382	24	by	by	IN
cord-322904-9mta0aem	382	25	HAs	have	VBZ
cord-322904-9mta0aem	382	26	,	,	,
cord-322904-9mta0aem	382	27	as	as	IN
cord-322904-9mta0aem	382	28	these	these	DT
cord-322904-9mta0aem	382	29	short	short	JJ
cord-322904-9mta0aem	382	30	glycans	glycan	NNS
cord-322904-9mta0aem	382	31	do	do	VBP
cord-322904-9mta0aem	382	32	not	not	RB
cord-322904-9mta0aem	382	33	adopt	adopt	VB
cord-322904-9mta0aem	382	34	the	the	DT
cord-322904-9mta0aem	382	35	umbrella	umbrella	NN
cord-322904-9mta0aem	382	36	shape	shape	NN
cord-322904-9mta0aem	382	37	that	that	WDT
cord-322904-9mta0aem	382	38	is	be	VBZ
cord-322904-9mta0aem	382	39	bound	bind	VBN
cord-322904-9mta0aem	382	40	by	by	IN
cord-322904-9mta0aem	382	41	human	human	JJ
cord-322904-9mta0aem	382	42	influenzaviruses	influenzaviruse	NNS
cord-322904-9mta0aem	382	43	.	.	.
cord-322904-9mta0aem	383	1	In	in	IN
cord-322904-9mta0aem	383	2	the	the	DT
cord-322904-9mta0aem	383	3	case	case	NN
cord-322904-9mta0aem	383	4	of	of	IN
cord-322904-9mta0aem	383	5	SV40	SV40	NNP
cord-322904-9mta0aem	383	6	,	,	,
cord-322904-9mta0aem	383	7	only	only	RB
cord-322904-9mta0aem	383	8	the	the	DT
cord-322904-9mta0aem	383	9	correct	correct	JJ
cord-322904-9mta0aem	383	10	GM1	GM1	NNP
cord-322904-9mta0aem	383	11	receptor	receptor	NN
cord-322904-9mta0aem	383	12	bound	bind	VBN
cord-322904-9mta0aem	383	13	to	to	IN
cord-322904-9mta0aem	383	14	the	the	DT
cord-322904-9mta0aem	383	15	protein	protein	NN
cord-322904-9mta0aem	383	16	.	.	.
cord-322904-9mta0aem	384	1	Smaller	small	JJR
cord-322904-9mta0aem	384	2	,	,	,
cord-322904-9mta0aem	384	3	unbranched	unbranched	JJ
cord-322904-9mta0aem	384	4	components	component	NNS
cord-322904-9mta0aem	384	5	of	of	IN
cord-322904-9mta0aem	384	6	the	the	DT
cord-322904-9mta0aem	384	7	GM1	GM1	NNP
cord-322904-9mta0aem	384	8	structure	structure	NN
cord-322904-9mta0aem	384	9	would	would	MD
cord-322904-9mta0aem	384	10	not	not	RB
cord-322904-9mta0aem	384	11	have	have	VB
cord-322904-9mta0aem	384	12	given	give	VBN
cord-322904-9mta0aem	384	13	insight	insight	NN
cord-322904-9mta0aem	384	14	into	into	IN
cord-322904-9mta0aem	384	15	SV40	SV40	NNP
cord-322904-9mta0aem	384	16	receptor	receptor	NN
cord-322904-9mta0aem	384	17	binding	binding	NN
cord-322904-9mta0aem	384	18	as	as	IN
cord-322904-9mta0aem	384	19	they	-PRON-	PRP
cord-322904-9mta0aem	384	20	do	do	VBP
cord-322904-9mta0aem	384	21	not	not	RB
cord-322904-9mta0aem	384	22	bind	bind	VB
cord-322904-9mta0aem	384	23	with	with	IN
cord-322904-9mta0aem	384	24	detectable	detectable	JJ
cord-322904-9mta0aem	384	25	affinity	affinity	NN
cord-322904-9mta0aem	384	26	(	(	-LRB-
cord-322904-9mta0aem	384	27	Neu	Neu	NNP
cord-322904-9mta0aem	384	28	et	et	FW
cord-322904-9mta0aem	384	29	al	al	NNP
cord-322904-9mta0aem	384	30	.	.	NNP
cord-322904-9mta0aem	384	31	,	,	,
cord-322904-9mta0aem	384	32	2008	2008	CD
cord-322904-9mta0aem	384	33	)	)	-RRB-
cord-322904-9mta0aem	384	34	.	.	.
cord-322904-9mta0aem	385	1	Several	several	JJ
cord-322904-9mta0aem	385	2	other	other	JJ
cord-322904-9mta0aem	385	3	viruses	virus	NNS
cord-322904-9mta0aem	385	4	,	,	,
cord-322904-9mta0aem	385	5	e.g.	e.g.	IN
cord-322904-9mta0aem	385	6	strains	strain	NNS
cord-322904-9mta0aem	385	7	of	of	IN
cord-322904-9mta0aem	385	8	coronavirus	coronavirus	NN
cord-322904-9mta0aem	385	9	and	and	CC
cord-322904-9mta0aem	385	10	reovirus	reovirus	NNP
cord-322904-9mta0aem	385	11	,	,	,
cord-322904-9mta0aem	385	12	bind	bind	VB
cord-322904-9mta0aem	385	13	sialylated	sialylated	JJ
cord-322904-9mta0aem	385	14	glycans	glycan	NNS
cord-322904-9mta0aem	385	15	,	,	,
cord-322904-9mta0aem	385	16	but	but	CC
cord-322904-9mta0aem	385	17	structural	structural	JJ
cord-322904-9mta0aem	385	18	information	information	NN
cord-322904-9mta0aem	385	19	about	about	IN
cord-322904-9mta0aem	385	20	these	these	DT
cord-322904-9mta0aem	385	21	interactions	interaction	NNS
cord-322904-9mta0aem	385	22	is	be	VBZ
cord-322904-9mta0aem	385	23	currently	currently	RB
cord-322904-9mta0aem	385	24	lacking	lack	VBG
cord-322904-9mta0aem	385	25	.	.	.
cord-322904-9mta0aem	386	1	The	the	DT
cord-322904-9mta0aem	386	2	availability	availability	NN
cord-322904-9mta0aem	386	3	of	of	IN
cord-322904-9mta0aem	386	4	complex	complex	JJ
cord-322904-9mta0aem	386	5	glycans	glycan	NNS
cord-322904-9mta0aem	386	6	and	and	CC
cord-322904-9mta0aem	386	7	the	the	DT
cord-322904-9mta0aem	386	8	use	use	NN
cord-322904-9mta0aem	386	9	of	of	IN
cord-322904-9mta0aem	386	10	glycan	glycan	NN
cord-322904-9mta0aem	386	11	screens	screen	NNS
cord-322904-9mta0aem	386	12	to	to	TO
cord-322904-9mta0aem	386	13	define	define	VB
cord-322904-9mta0aem	386	14	binding	bind	VBG
cord-322904-9mta0aem	386	15	specificity	specificity	NN
cord-322904-9mta0aem	386	16	have	have	VBP
cord-322904-9mta0aem	386	17	proven	prove	VBN
cord-322904-9mta0aem	386	18	of	of	IN
cord-322904-9mta0aem	386	19	great	great	JJ
cord-322904-9mta0aem	386	20	importance	importance	NN
cord-322904-9mta0aem	386	21	and	and	CC
cord-322904-9mta0aem	386	22	will	will	MD
cord-322904-9mta0aem	386	23	undoubtedly	undoubtedly	RB
cord-322904-9mta0aem	386	24	advance	advance	VB
cord-322904-9mta0aem	386	25	the	the	DT
cord-322904-9mta0aem	386	26	understanding	understanding	NN
cord-322904-9mta0aem	386	27	of	of	IN
cord-322904-9mta0aem	386	28	glycan	glycan	NN
cord-322904-9mta0aem	386	29	binding	binding	NN
cord-322904-9mta0aem	386	30	by	by	IN
cord-322904-9mta0aem	386	31	these	these	DT
cord-322904-9mta0aem	386	32	other	other	JJ
cord-322904-9mta0aem	386	33	viruses	virus	NNS
cord-322904-9mta0aem	386	34	.	.	.
cord-322904-9mta0aem	387	1	The	the	DT
cord-322904-9mta0aem	387	2	original	original	JJ
cord-322904-9mta0aem	387	3	studies	study	NNS
cord-322904-9mta0aem	387	4	describing	describe	VBG
cord-322904-9mta0aem	387	5	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	387	6	host	host	NN
cord-322904-9mta0aem	387	7	cell	cell	NN
cord-322904-9mta0aem	387	8	interactions	interaction	NNS
cord-322904-9mta0aem	387	9	depicted	depict	VBD
cord-322904-9mta0aem	387	10	infection	infection	NN
cord-322904-9mta0aem	387	11	as	as	IN
cord-322904-9mta0aem	387	12	involving	involve	VBG
cord-322904-9mta0aem	387	13	a	a	DT
cord-322904-9mta0aem	387	14	series	series	NN
cord-322904-9mta0aem	387	15	of	of	IN
cord-322904-9mta0aem	387	16	discrete	discrete	JJ
cord-322904-9mta0aem	387	17	steps	step	NNS
cord-322904-9mta0aem	387	18	that	that	WDT
cord-322904-9mta0aem	387	19	included	include	VBD
cord-322904-9mta0aem	387	20	virus	virus	NN
cord-322904-9mta0aem	387	21	adsorption	adsorption	NN
cord-322904-9mta0aem	387	22	,	,	,
cord-322904-9mta0aem	387	23	virus	virus	NN
cord-322904-9mta0aem	387	24	entry	entry	NN
cord-322904-9mta0aem	387	25	into	into	IN
cord-322904-9mta0aem	387	26	membrane	membrane	NN
cord-322904-9mta0aem	387	27	bound	bind	VBN
cord-322904-9mta0aem	387	28	organelles	organelle	NNS
cord-322904-9mta0aem	387	29	,	,	,
cord-322904-9mta0aem	387	30	and	and	CC
cord-322904-9mta0aem	387	31	virus	virus	NN
cord-322904-9mta0aem	387	32	trafficking	trafficking	NN
cord-322904-9mta0aem	387	33	by	by	IN
cord-322904-9mta0aem	387	34	sequential	sequential	JJ
cord-322904-9mta0aem	387	35	membrane	membrane	NN
cord-322904-9mta0aem	387	36	fusion	fusion	NN
cord-322904-9mta0aem	387	37	and	and	CC
cord-322904-9mta0aem	387	38	fission	fission	NN
cord-322904-9mta0aem	387	39	events	event	NNS
cord-322904-9mta0aem	387	40	.	.	.
cord-322904-9mta0aem	388	1	Although	although	IN
cord-322904-9mta0aem	388	2	there	there	EX
cord-322904-9mta0aem	388	3	was	be	VBD
cord-322904-9mta0aem	388	4	controversy	controversy	NN
cord-322904-9mta0aem	388	5	regarding	regard	VBG
cord-322904-9mta0aem	388	6	whether	whether	IN
cord-322904-9mta0aem	388	7	these	these	DT
cord-322904-9mta0aem	388	8	viruses	virus	NNS
cord-322904-9mta0aem	388	9	could	could	MD
cord-322904-9mta0aem	388	10	penetrate	penetrate	VB
cord-322904-9mta0aem	388	11	the	the	DT
cord-322904-9mta0aem	388	12	nuclear	nuclear	JJ
cord-322904-9mta0aem	388	13	envelope	envelope	NN
cord-322904-9mta0aem	388	14	intact	intact	JJ
cord-322904-9mta0aem	388	15	an	an	DT
cord-322904-9mta0aem	388	16	early	early	JJ
cord-322904-9mta0aem	388	17	pivotal	pivotal	JJ
cord-322904-9mta0aem	388	18	study	study	NN
cord-322904-9mta0aem	388	19	demonstrated	demonstrate	VBD
cord-322904-9mta0aem	388	20	that	that	IN
cord-322904-9mta0aem	388	21	the	the	DT
cord-322904-9mta0aem	388	22	virus	virus	NN
cord-322904-9mta0aem	388	23	capsid	capsid	NN
cord-322904-9mta0aem	388	24	only	only	RB
cord-322904-9mta0aem	388	25	penetrates	penetrate	VBZ
cord-322904-9mta0aem	388	26	the	the	DT
cord-322904-9mta0aem	388	27	outer	outer	JJ
cord-322904-9mta0aem	388	28	nuclear	nuclear	JJ
cord-322904-9mta0aem	388	29	envelope	envelope	NN
cord-322904-9mta0aem	388	30	.	.	.
cord-322904-9mta0aem	389	1	Recent	recent	JJ
cord-322904-9mta0aem	389	2	studies	study	NNS
cord-322904-9mta0aem	389	3	on	on	IN
cord-322904-9mta0aem	389	4	these	these	DT
cord-322904-9mta0aem	389	5	viruses	virus	NNS
cord-322904-9mta0aem	389	6	describe	describe	VBP
cord-322904-9mta0aem	389	7	largely	largely	RB
cord-322904-9mta0aem	389	8	the	the	DT
cord-322904-9mta0aem	389	9	same	same	JJ
cord-322904-9mta0aem	389	10	series	series	NN
cord-322904-9mta0aem	389	11	of	of	IN
cord-322904-9mta0aem	389	12	steps	step	NNS
cord-322904-9mta0aem	389	13	but	but	CC
cord-322904-9mta0aem	389	14	in	in	IN
cord-322904-9mta0aem	389	15	significantly	significantly	RB
cord-322904-9mta0aem	389	16	more	more	JJR
cord-322904-9mta0aem	389	17	detail	detail	NN
cord-322904-9mta0aem	389	18	.	.	.
cord-322904-9mta0aem	390	1	We	-PRON-	PRP
cord-322904-9mta0aem	390	2	now	now	RB
cord-322904-9mta0aem	390	3	know	know	VBP
cord-322904-9mta0aem	390	4	and	and	CC
cord-322904-9mta0aem	390	5	appreciate	appreciate	VBP
cord-322904-9mta0aem	390	6	that	that	IN
cord-322904-9mta0aem	390	7	the	the	DT
cord-322904-9mta0aem	390	8	majority	majority	NN
cord-322904-9mta0aem	390	9	of	of	IN
cord-322904-9mta0aem	390	10	these	these	DT
cord-322904-9mta0aem	390	11	viruses	virus	NNS
cord-322904-9mta0aem	390	12	recognize	recognize	VBP
cord-322904-9mta0aem	390	13	specific	specific	JJ
cord-322904-9mta0aem	390	14	linkages	linkage	NNS
cord-322904-9mta0aem	390	15	of	of	IN
cord-322904-9mta0aem	390	16	sialic	sialic	JJ
cord-322904-9mta0aem	390	17	acid	acid	NN
cord-322904-9mta0aem	390	18	on	on	IN
cord-322904-9mta0aem	390	19	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	390	20	and	and	CC
cord-322904-9mta0aem	390	21	glycoproteins	glycoprotein	NNS
cord-322904-9mta0aem	390	22	.	.	.
cord-322904-9mta0aem	391	1	These	these	DT
cord-322904-9mta0aem	391	2	viruses	virus	NNS
cord-322904-9mta0aem	391	3	also	also	RB
cord-322904-9mta0aem	391	4	recognize	recognize	VBP
cord-322904-9mta0aem	391	5	other	other	JJ
cord-322904-9mta0aem	391	6	cellular	cellular	JJ
cord-322904-9mta0aem	391	7	components	component	NNS
cord-322904-9mta0aem	391	8	such	such	JJ
cord-322904-9mta0aem	391	9	as	as	IN
cord-322904-9mta0aem	391	10	the	the	DT
cord-322904-9mta0aem	391	11	5HT2a	5ht2a	CD
cord-322904-9mta0aem	391	12	receptor	receptor	NN
cord-322904-9mta0aem	391	13	for	for	IN
cord-322904-9mta0aem	391	14	JCV	JCV	NNP
cord-322904-9mta0aem	391	15	,	,	,
cord-322904-9mta0aem	391	16	α4β1	α4β1	NNP
cord-322904-9mta0aem	391	17	integrin	integrin	NN
cord-322904-9mta0aem	391	18	for	for	IN
cord-322904-9mta0aem	391	19	mPyV	mPyV	NNP
cord-322904-9mta0aem	391	20	,	,	,
cord-322904-9mta0aem	391	21	and	and	CC
cord-322904-9mta0aem	391	22	the	the	DT
cord-322904-9mta0aem	391	23	MHC	MHC	NNP
cord-322904-9mta0aem	391	24	class	class	NN
cord-322904-9mta0aem	391	25	I	-PRON-	PRP
cord-322904-9mta0aem	391	26	protein	protein	VBP
cord-322904-9mta0aem	391	27	for	for	IN
cord-322904-9mta0aem	391	28	SV40	SV40	NNP
cord-322904-9mta0aem	391	29	,	,	,
cord-322904-9mta0aem	391	30	likely	likely	JJ
cord-322904-9mta0aem	391	31	as	as	IN
cord-322904-9mta0aem	391	32	part	part	NN
cord-322904-9mta0aem	391	33	of	of	IN
cord-322904-9mta0aem	391	34	a	a	DT
cord-322904-9mta0aem	391	35	receptor	receptor	NN
cord-322904-9mta0aem	391	36	complex	complex	NN
cord-322904-9mta0aem	391	37	with	with	IN
cord-322904-9mta0aem	391	38	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	391	39	or	or	CC
cord-322904-9mta0aem	391	40	other	other	JJ
cord-322904-9mta0aem	391	41	sialic	sialic	JJ
cord-322904-9mta0aem	391	42	acid	acid	NN
cord-322904-9mta0aem	391	43	containing	contain	VBG
cord-322904-9mta0aem	391	44	structures	structure	NNS
cord-322904-9mta0aem	391	45	.	.	.
cord-322904-9mta0aem	392	1	There	there	EX
cord-322904-9mta0aem	392	2	are	be	VBP
cord-322904-9mta0aem	392	3	clear	clear	JJ
cord-322904-9mta0aem	392	4	cell	cell	NN
cord-322904-9mta0aem	392	5	type	type	NN
cord-322904-9mta0aem	392	6	specific	specific	JJ
cord-322904-9mta0aem	392	7	and	and	CC
cord-322904-9mta0aem	392	8	viral	viral	JJ
cord-322904-9mta0aem	392	9	strain	strain	NN
cord-322904-9mta0aem	392	10	differences	difference	NNS
cord-322904-9mta0aem	392	11	that	that	WDT
cord-322904-9mta0aem	392	12	determine	determine	VBP
cord-322904-9mta0aem	392	13	what	what	WDT
cord-322904-9mta0aem	392	14	components	component	NNS
cord-322904-9mta0aem	392	15	of	of	IN
cord-322904-9mta0aem	392	16	the	the	DT
cord-322904-9mta0aem	392	17	receptor	receptor	NN
cord-322904-9mta0aem	392	18	complex	complex	NN
cord-322904-9mta0aem	392	19	are	be	VBP
cord-322904-9mta0aem	392	20	required	require	VBN
cord-322904-9mta0aem	392	21	to	to	TO
cord-322904-9mta0aem	392	22	initiate	initiate	VB
cord-322904-9mta0aem	392	23	infection	infection	NN
cord-322904-9mta0aem	392	24	.	.	.
cord-322904-9mta0aem	393	1	Once	once	RB
cord-322904-9mta0aem	393	2	bound	bind	VBN
cord-322904-9mta0aem	393	3	to	to	TO
cord-322904-9mta0aem	393	4	cells	cell	NNS
cord-322904-9mta0aem	393	5	all	all	DT
cord-322904-9mta0aem	393	6	of	of	IN
cord-322904-9mta0aem	393	7	these	these	DT
cord-322904-9mta0aem	393	8	viruses	virus	NNS
cord-322904-9mta0aem	394	1	induce	induce	VB
cord-322904-9mta0aem	394	2	molecular	molecular	JJ
cord-322904-9mta0aem	394	3	signals	signal	NNS
cord-322904-9mta0aem	394	4	that	that	WDT
cord-322904-9mta0aem	394	5	initiate	initiate	VBP
cord-322904-9mta0aem	394	6	infectious	infectious	JJ
cord-322904-9mta0aem	394	7	entry	entry	NN
cord-322904-9mta0aem	394	8	.	.	.
cord-322904-9mta0aem	395	1	The	the	DT
cord-322904-9mta0aem	395	2	mPyV	mpyv	NN
cord-322904-9mta0aem	395	3	,	,	,
cord-322904-9mta0aem	395	4	SV40	SV40	NNP
cord-322904-9mta0aem	395	5	,	,	,
cord-322904-9mta0aem	395	6	and	and	CC
cord-322904-9mta0aem	395	7	BKV	BKV	NNP
cord-322904-9mta0aem	395	8	all	all	DT
cord-322904-9mta0aem	395	9	infect	infect	VBP
cord-322904-9mta0aem	395	10	cells	cell	NNS
cord-322904-9mta0aem	395	11	by	by	IN
cord-322904-9mta0aem	395	12	caveolae	caveolae	NNP
cord-322904-9mta0aem	395	13	dependent	dependent	JJ
cord-322904-9mta0aem	395	14	endocytosis	endocytosis	NN
cord-322904-9mta0aem	395	15	.	.	.
cord-322904-9mta0aem	396	1	Non	non	JJ
cord-322904-9mta0aem	396	2	-	-	JJ
cord-322904-9mta0aem	396	3	caveolar	caveolar	JJ
cord-322904-9mta0aem	396	4	cholesterol	cholesterol	NN
cord-322904-9mta0aem	396	5	dependent	dependent	JJ
cord-322904-9mta0aem	396	6	mechanisms	mechanism	NNS
cord-322904-9mta0aem	396	7	can	can	MD
cord-322904-9mta0aem	396	8	also	also	RB
cord-322904-9mta0aem	396	9	be	be	VB
cord-322904-9mta0aem	396	10	exploited	exploit	VBN
cord-322904-9mta0aem	396	11	by	by	IN
cord-322904-9mta0aem	396	12	some	some	DT
cord-322904-9mta0aem	396	13	of	of	IN
cord-322904-9mta0aem	396	14	these	these	DT
cord-322904-9mta0aem	396	15	viruses	virus	NNS
cord-322904-9mta0aem	396	16	depending	depend	VBG
cord-322904-9mta0aem	396	17	on	on	IN
cord-322904-9mta0aem	396	18	cell	cell	NN
cord-322904-9mta0aem	396	19	type	type	NN
cord-322904-9mta0aem	396	20	.	.	.
cord-322904-9mta0aem	397	1	Downstream	downstream	IN
cord-322904-9mta0aem	397	2	of	of	IN
cord-322904-9mta0aem	397	3	both	both	DT
cord-322904-9mta0aem	397	4	caveolae	caveolae	NNP
cord-322904-9mta0aem	397	5	and	and	CC
cord-322904-9mta0aem	397	6	raft	raft	JJ
cord-322904-9mta0aem	397	7	dependent	dependent	JJ
cord-322904-9mta0aem	397	8	mechanisms	mechanism	NNS
cord-322904-9mta0aem	397	9	the	the	DT
cord-322904-9mta0aem	397	10	viruses	virus	NNS
cord-322904-9mta0aem	397	11	traffic	traffic	NN
cord-322904-9mta0aem	397	12	to	to	IN
cord-322904-9mta0aem	397	13	a	a	DT
cord-322904-9mta0aem	397	14	pH	pH	NNP
cord-322904-9mta0aem	397	15	neutral	neutral	JJ
cord-322904-9mta0aem	397	16	caveosome	caveosome	NNP
cord-322904-9mta0aem	397	17	that	that	WDT
cord-322904-9mta0aem	397	18	lacks	lack	VBZ
cord-322904-9mta0aem	397	19	markers	marker	NNS
cord-322904-9mta0aem	397	20	of	of	IN
cord-322904-9mta0aem	397	21	other	other	JJ
cord-322904-9mta0aem	397	22	cellular	cellular	JJ
cord-322904-9mta0aem	397	23	organelles	organelle	NNS
cord-322904-9mta0aem	397	24	.	.	.
cord-322904-9mta0aem	398	1	High	high	JJ
cord-322904-9mta0aem	398	2	resolution	resolution	NN
cord-322904-9mta0aem	398	3	video	video	NN
cord-322904-9mta0aem	398	4	microscopy	microscopy	NN
cord-322904-9mta0aem	398	5	of	of	IN
cord-322904-9mta0aem	398	6	virus	virus	NN
cord-322904-9mta0aem	398	7	entry	entry	NN
cord-322904-9mta0aem	398	8	has	have	VBZ
cord-322904-9mta0aem	398	9	found	find	VBN
cord-322904-9mta0aem	398	10	that	that	IN
cord-322904-9mta0aem	398	11	these	these	DT
cord-322904-9mta0aem	398	12	viruses	virus	NNS
cord-322904-9mta0aem	398	13	are	be	VBP
cord-322904-9mta0aem	398	14	trafficked	traffic	VBN
cord-322904-9mta0aem	398	15	out	out	IN
cord-322904-9mta0aem	398	16	of	of	IN
cord-322904-9mta0aem	398	17	the	the	DT
cord-322904-9mta0aem	398	18	caveosomes	caveosome	NNS
cord-322904-9mta0aem	398	19	in	in	IN
cord-322904-9mta0aem	398	20	elongated	elongated	JJ
cord-322904-9mta0aem	398	21	tubular	tubular	JJ
cord-322904-9mta0aem	398	22	structures	structure	NNS
cord-322904-9mta0aem	398	23	that	that	WDT
cord-322904-9mta0aem	398	24	fuse	fuse	VBP
cord-322904-9mta0aem	398	25	with	with	IN
cord-322904-9mta0aem	398	26	the	the	DT
cord-322904-9mta0aem	398	27	ER	ER	NNP
cord-322904-9mta0aem	398	28	membrane	membrane	NN
cord-322904-9mta0aem	398	29	.	.	.
cord-322904-9mta0aem	399	1	This	this	DT
cord-322904-9mta0aem	399	2	trafficking	trafficking	NN
cord-322904-9mta0aem	399	3	step	step	NN
cord-322904-9mta0aem	399	4	is	be	VBZ
cord-322904-9mta0aem	399	5	dependent	dependent	JJ
cord-322904-9mta0aem	399	6	on	on	IN
cord-322904-9mta0aem	399	7	microtubules	microtubule	NNS
cord-322904-9mta0aem	399	8	.	.	.
cord-322904-9mta0aem	400	1	The	the	DT
cord-322904-9mta0aem	400	2	human	human	JJ
cord-322904-9mta0aem	400	3	polyomavirus	polyomavirus	NN
cord-322904-9mta0aem	400	4	,	,	,
cord-322904-9mta0aem	400	5	JCV	JCV	NNP
cord-322904-9mta0aem	400	6	,	,	,
cord-322904-9mta0aem	400	7	appears	appear	VBZ
cord-322904-9mta0aem	400	8	to	to	TO
cord-322904-9mta0aem	400	9	be	be	VB
cord-322904-9mta0aem	400	10	an	an	DT
cord-322904-9mta0aem	400	11	exception	exception	NN
cord-322904-9mta0aem	400	12	and	and	CC
cord-322904-9mta0aem	400	13	rather	rather	RB
cord-322904-9mta0aem	400	14	than	than	IN
cord-322904-9mta0aem	400	15	utilizing	utilize	VBG
cord-322904-9mta0aem	400	16	caveloae	caveloae	NNP
cord-322904-9mta0aem	400	17	to	to	TO
cord-322904-9mta0aem	400	18	enter	enter	VB
cord-322904-9mta0aem	400	19	cells	cell	NNS
cord-322904-9mta0aem	400	20	this	this	DT
cord-322904-9mta0aem	400	21	virus	virus	NN
cord-322904-9mta0aem	400	22	exploits	exploit	VBZ
cord-322904-9mta0aem	400	23	clathrin	clathrin	VBP
cord-322904-9mta0aem	400	24	dependent	dependent	JJ
cord-322904-9mta0aem	400	25	mechanisms	mechanism	NNS
cord-322904-9mta0aem	400	26	to	to	TO
cord-322904-9mta0aem	400	27	initially	initially	RB
cord-322904-9mta0aem	400	28	traffic	traffic	VB
cord-322904-9mta0aem	400	29	to	to	IN
cord-322904-9mta0aem	400	30	early	early	JJ
cord-322904-9mta0aem	400	31	endosomes	endosome	NNS
cord-322904-9mta0aem	400	32	.	.	.
cord-322904-9mta0aem	401	1	In	in	IN
cord-322904-9mta0aem	401	2	the	the	DT
cord-322904-9mta0aem	401	3	early	early	JJ
cord-322904-9mta0aem	401	4	endosomes	endosome	NNS
cord-322904-9mta0aem	401	5	JCV	JCV	NNP
cord-322904-9mta0aem	401	6	is	be	VBZ
cord-322904-9mta0aem	401	7	found	find	VBN
cord-322904-9mta0aem	401	8	to	to	TO
cord-322904-9mta0aem	401	9	be	be	VB
cord-322904-9mta0aem	401	10	tightly	tightly	RB
cord-322904-9mta0aem	401	11	opposed	opposed	JJ
cord-322904-9mta0aem	401	12	to	to	IN
cord-322904-9mta0aem	401	13	the	the	DT
cord-322904-9mta0aem	401	14	inner	inner	JJ
cord-322904-9mta0aem	401	15	leaflet	leaflet	NN
cord-322904-9mta0aem	401	16	of	of	IN
cord-322904-9mta0aem	401	17	the	the	DT
cord-322904-9mta0aem	401	18	endosome	endosome	NN
cord-322904-9mta0aem	401	19	and	and	CC
cord-322904-9mta0aem	401	20	in	in	IN
cord-322904-9mta0aem	401	21	a	a	DT
cord-322904-9mta0aem	401	22	pH	ph	NN
cord-322904-9mta0aem	401	23	and	and	CC
cord-322904-9mta0aem	401	24	Rab5	Rab5	NNP
cord-322904-9mta0aem	401	25	dependent	dependent	JJ
cord-322904-9mta0aem	401	26	step	step	NN
cord-322904-9mta0aem	401	27	traffics	traffic	VBZ
cord-322904-9mta0aem	401	28	from	from	IN
cord-322904-9mta0aem	401	29	the	the	DT
cord-322904-9mta0aem	401	30	early	early	JJ
cord-322904-9mta0aem	401	31	endosome	endosome	NN
cord-322904-9mta0aem	401	32	to	to	IN
cord-322904-9mta0aem	401	33	caveosomes	caveosome	NNS
cord-322904-9mta0aem	401	34	.	.	.
cord-322904-9mta0aem	402	1	At	at	IN
cord-322904-9mta0aem	402	2	this	this	DT
cord-322904-9mta0aem	402	3	point	point	NN
cord-322904-9mta0aem	402	4	the	the	DT
cord-322904-9mta0aem	402	5	virus	virus	NN
cord-322904-9mta0aem	402	6	likely	likely	RB
cord-322904-9mta0aem	402	7	follows	follow	VBZ
cord-322904-9mta0aem	402	8	the	the	DT
cord-322904-9mta0aem	402	9	fate	fate	NN
cord-322904-9mta0aem	402	10	of	of	IN
cord-322904-9mta0aem	402	11	other	other	JJ
cord-322904-9mta0aem	402	12	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	402	13	and	and	CC
cord-322904-9mta0aem	402	14	travels	travel	VBZ
cord-322904-9mta0aem	402	15	to	to	IN
cord-322904-9mta0aem	402	16	the	the	DT
cord-322904-9mta0aem	402	17	ER	ER	NNP
cord-322904-9mta0aem	402	18	.	.	.
cord-322904-9mta0aem	403	1	Once	once	RB
cord-322904-9mta0aem	403	2	in	in	IN
cord-322904-9mta0aem	403	3	the	the	DT
cord-322904-9mta0aem	403	4	ER	er	NN
cord-322904-9mta0aem	403	5	the	the	DT
cord-322904-9mta0aem	403	6	viruses	virus	NNS
cord-322904-9mta0aem	403	7	take	take	VBP
cord-322904-9mta0aem	403	8	advantage	advantage	NN
cord-322904-9mta0aem	403	9	of	of	IN
cord-322904-9mta0aem	403	10	protein	protein	NN
cord-322904-9mta0aem	403	11	disulfide	disulfide	NN
cord-322904-9mta0aem	403	12	isomerases	isomerase	NNS
cord-322904-9mta0aem	403	13	to	to	TO
cord-322904-9mta0aem	403	14	rearrange	rearrange	VB
cord-322904-9mta0aem	403	15	their	-PRON-	PRP$
cord-322904-9mta0aem	403	16	capsid	capsid	JJ
cord-322904-9mta0aem	403	17	structure	structure	NN
cord-322904-9mta0aem	403	18	.	.	.
cord-322904-9mta0aem	404	1	In	in	IN
cord-322904-9mta0aem	404	2	the	the	DT
cord-322904-9mta0aem	404	3	case	case	NN
cord-322904-9mta0aem	404	4	of	of	IN
cord-322904-9mta0aem	404	5	SV40	SV40	NNP
cord-322904-9mta0aem	404	6	,	,	,
cord-322904-9mta0aem	404	7	PDI	PDI	NNP
cord-322904-9mta0aem	404	8	and	and	CC
cord-322904-9mta0aem	404	9	ERp57	ERp57	NNS
cord-322904-9mta0aem	404	10	rearrange	rearrange	VBP
cord-322904-9mta0aem	404	11	the	the	DT
cord-322904-9mta0aem	404	12	12	12	CD
cord-322904-9mta0aem	404	13	five	five	CD
cord-322904-9mta0aem	404	14	-	-	HYPH
cord-322904-9mta0aem	404	15	coordinated	coordinate	VBN
cord-322904-9mta0aem	404	16	VP1	vp1	NN
cord-322904-9mta0aem	404	17	pentamers	pentamer	NNS
cord-322904-9mta0aem	404	18	.	.	.
cord-322904-9mta0aem	405	1	The	the	DT
cord-322904-9mta0aem	405	2	now	now	RB
cord-322904-9mta0aem	405	3	misfolded	misfolde	VBN
cord-322904-9mta0aem	405	4	structure	structure	NN
cord-322904-9mta0aem	405	5	is	be	VBZ
cord-322904-9mta0aem	405	6	recognized	recognize	VBN
cord-322904-9mta0aem	405	7	by	by	IN
cord-322904-9mta0aem	405	8	components	component	NNS
cord-322904-9mta0aem	405	9	of	of	IN
cord-322904-9mta0aem	405	10	the	the	DT
cord-322904-9mta0aem	405	11	ERAD	ERAD	NNP
cord-322904-9mta0aem	405	12	pathway	pathway	NN
cord-322904-9mta0aem	405	13	(	(	-LRB-
cord-322904-9mta0aem	405	14	Derlin	Derlin	NNP
cord-322904-9mta0aem	405	15	1	1	CD
cord-322904-9mta0aem	405	16	,	,	,
cord-322904-9mta0aem	405	17	SelL1	SelL1	NNP
cord-322904-9mta0aem	405	18	)	)	-RRB-
cord-322904-9mta0aem	405	19	and	and	CC
cord-322904-9mta0aem	405	20	exported	export	VBN
cord-322904-9mta0aem	405	21	to	to	IN
cord-322904-9mta0aem	405	22	the	the	DT
cord-322904-9mta0aem	405	23	cytosol	cytosol	NN
cord-322904-9mta0aem	405	24	.	.	.
cord-322904-9mta0aem	406	1	Calcium	calcium	NN
cord-322904-9mta0aem	406	2	levels	level	NNS
cord-322904-9mta0aem	406	3	in	in	IN
cord-322904-9mta0aem	406	4	the	the	DT
cord-322904-9mta0aem	406	5	cytosol	cytosol	NN
cord-322904-9mta0aem	406	6	of	of	IN
cord-322904-9mta0aem	406	7	resting	rest	VBG
cord-322904-9mta0aem	406	8	cells	cell	NNS
cord-322904-9mta0aem	406	9	are	be	VBP
cord-322904-9mta0aem	406	10	significantly	significantly	RB
cord-322904-9mta0aem	406	11	lower	low	JJR
cord-322904-9mta0aem	406	12	(	(	-LRB-
cord-322904-9mta0aem	406	13	0.1	0.1	CD
cord-322904-9mta0aem	406	14	μM	μm	CD
cord-322904-9mta0aem	406	15	)	)	-RRB-
cord-322904-9mta0aem	406	16	than	than	IN
cord-322904-9mta0aem	406	17	levels	level	NNS
cord-322904-9mta0aem	406	18	in	in	IN
cord-322904-9mta0aem	406	19	the	the	DT
cord-322904-9mta0aem	406	20	ER	ER	NNP
cord-322904-9mta0aem	406	21	(	(	-LRB-
cord-322904-9mta0aem	406	22	100	100	CD
cord-322904-9mta0aem	406	23	-	-	SYM
cord-322904-9mta0aem	406	24	400	400	CD
cord-322904-9mta0aem	406	25	μM	μm	CD
cord-322904-9mta0aem	406	26	)	)	-RRB-
cord-322904-9mta0aem	406	27	.	.	.
cord-322904-9mta0aem	407	1	As	as	IN
cord-322904-9mta0aem	407	2	calcium	calcium	NN
cord-322904-9mta0aem	407	3	is	be	VBZ
cord-322904-9mta0aem	407	4	required	require	VBN
cord-322904-9mta0aem	407	5	to	to	TO
cord-322904-9mta0aem	407	6	stabilize	stabilize	VB
cord-322904-9mta0aem	407	7	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	407	8	virions	virion	NNS
cord-322904-9mta0aem	407	9	the	the	DT
cord-322904-9mta0aem	407	10	low	low	JJ
cord-322904-9mta0aem	407	11	levels	level	NNS
cord-322904-9mta0aem	407	12	of	of	IN
cord-322904-9mta0aem	407	13	calcium	calcium	NN
cord-322904-9mta0aem	407	14	encountered	encounter	VBN
cord-322904-9mta0aem	407	15	as	as	IN
cord-322904-9mta0aem	408	1	the	the	DT
cord-322904-9mta0aem	408	2	destabilized	destabilize	VBN
cord-322904-9mta0aem	408	3	virus	virus	NN
cord-322904-9mta0aem	408	4	exits	exit	VBZ
cord-322904-9mta0aem	408	5	the	the	DT
cord-322904-9mta0aem	408	6	ERAD	ERAD	NNP
cord-322904-9mta0aem	408	7	pathway	pathway	NN
cord-322904-9mta0aem	408	8	are	be	VBP
cord-322904-9mta0aem	408	9	likely	likely	JJ
cord-322904-9mta0aem	408	10	sufficient	sufficient	JJ
cord-322904-9mta0aem	408	11	to	to	TO
cord-322904-9mta0aem	408	12	further	further	RB
cord-322904-9mta0aem	408	13	distort	distort	VB
cord-322904-9mta0aem	408	14	and	and	CC
cord-322904-9mta0aem	408	15	disassemble	disassemble	VB
cord-322904-9mta0aem	408	16	the	the	DT
cord-322904-9mta0aem	408	17	virion	virion	NN
cord-322904-9mta0aem	408	18	and	and	CC
cord-322904-9mta0aem	408	19	prepare	prepare	VB
cord-322904-9mta0aem	408	20	it	-PRON-	PRP
cord-322904-9mta0aem	408	21	for	for	IN
cord-322904-9mta0aem	408	22	transport	transport	NN
cord-322904-9mta0aem	408	23	through	through	IN
cord-322904-9mta0aem	408	24	the	the	DT
cord-322904-9mta0aem	408	25	nuclear	nuclear	JJ
cord-322904-9mta0aem	408	26	pore	pore	NN
cord-322904-9mta0aem	408	27	.	.	.
cord-322904-9mta0aem	409	1	In	in	IN
cord-322904-9mta0aem	409	2	the	the	DT
cord-322904-9mta0aem	409	3	case	case	NN
cord-322904-9mta0aem	409	4	of	of	IN
cord-322904-9mta0aem	409	5	mPyV	mPyV	NNP
cord-322904-9mta0aem	409	6	a	a	DT
cord-322904-9mta0aem	409	7	novel	novel	JJ
cord-322904-9mta0aem	409	8	PDI	PDI	NNP
cord-322904-9mta0aem	409	9	like	like	IN
cord-322904-9mta0aem	409	10	protein	protein	NN
cord-322904-9mta0aem	409	11	,	,	,
cord-322904-9mta0aem	409	12	ERp29	ERp29	NNS
cord-322904-9mta0aem	409	13	acts	act	VBZ
cord-322904-9mta0aem	409	14	to	to	TO
cord-322904-9mta0aem	409	15	unfold	unfold	VB
cord-322904-9mta0aem	409	16	VP1	VP1	NNP
cord-322904-9mta0aem	409	17	exposing	expose	VBG
cord-322904-9mta0aem	409	18	a	a	DT
cord-322904-9mta0aem	409	19	protease	protease	NN
cord-322904-9mta0aem	409	20	sensitive	sensitive	JJ
cord-322904-9mta0aem	409	21	site	site	NN
cord-322904-9mta0aem	409	22	in	in	IN
cord-322904-9mta0aem	409	23	the	the	DT
cord-322904-9mta0aem	409	24	Cterminal	Cterminal	NNP
cord-322904-9mta0aem	409	25	arm	arm	NN
cord-322904-9mta0aem	409	26	of	of	IN
cord-322904-9mta0aem	409	27	the	the	DT
cord-322904-9mta0aem	409	28	protein	protein	NN
cord-322904-9mta0aem	409	29	.	.	.
cord-322904-9mta0aem	410	1	Once	once	RB
cord-322904-9mta0aem	410	2	cleaved	cleave	VBD
cord-322904-9mta0aem	410	3	the	the	DT
cord-322904-9mta0aem	410	4	destabilized	destabilized	JJ
cord-322904-9mta0aem	410	5	particle	particle	NN
cord-322904-9mta0aem	410	6	can	can	MD
cord-322904-9mta0aem	410	7	insert	insert	VB
cord-322904-9mta0aem	410	8	into	into	IN
cord-322904-9mta0aem	410	9	a	a	DT
cord-322904-9mta0aem	410	10	lipid	lipid	NN
cord-322904-9mta0aem	410	11	membrane	membrane	NN
cord-322904-9mta0aem	410	12	.	.	.
cord-322904-9mta0aem	411	1	The	the	DT
cord-322904-9mta0aem	411	2	virus	virus	NN
cord-322904-9mta0aem	411	3	may	may	MD
cord-322904-9mta0aem	411	4	directly	directly	RB
cord-322904-9mta0aem	411	5	escape	escape	VB
cord-322904-9mta0aem	411	6	the	the	DT
cord-322904-9mta0aem	411	7	ER	er	NN
cord-322904-9mta0aem	411	8	via	via	IN
cord-322904-9mta0aem	411	9	this	this	DT
cord-322904-9mta0aem	411	10	mechanism	mechanism	NN
cord-322904-9mta0aem	411	11	or	or	CC
cord-322904-9mta0aem	411	12	it	-PRON-	PRP
cord-322904-9mta0aem	411	13	might	may	MD
cord-322904-9mta0aem	411	14	utilize	utilize	VB
cord-322904-9mta0aem	411	15	the	the	DT
cord-322904-9mta0aem	411	16	retrotranslocator	retrotranslocator	NN
cord-322904-9mta0aem	411	17	Derlin	Derlin	NNP
cord-322904-9mta0aem	411	18	2	2	CD
cord-322904-9mta0aem	411	19	as	as	IN
cord-322904-9mta0aem	411	20	inhibition	inhibition	NN
cord-322904-9mta0aem	411	21	of	of	IN
cord-322904-9mta0aem	411	22	this	this	DT
cord-322904-9mta0aem	411	23	protein	protein	NN
cord-322904-9mta0aem	411	24	reduces	reduce	VBZ
cord-322904-9mta0aem	411	25	mPyV	mpyv	JJ
cord-322904-9mta0aem	411	26	infection	infection	NN
cord-322904-9mta0aem	411	27	.	.	.
cord-322904-9mta0aem	412	1	It	-PRON-	PRP
cord-322904-9mta0aem	412	2	is	be	VBZ
cord-322904-9mta0aem	412	3	likely	likely	JJ
cord-322904-9mta0aem	412	4	that	that	IN
cord-322904-9mta0aem	412	5	the	the	DT
cord-322904-9mta0aem	412	6	two	two	CD
cord-322904-9mta0aem	412	7	human	human	JJ
cord-322904-9mta0aem	412	8	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	412	9	use	use	VBP
cord-322904-9mta0aem	412	10	similar	similar	JJ
cord-322904-9mta0aem	412	11	mechanisms	mechanism	NNS
cord-322904-9mta0aem	412	12	to	to	TO
cord-322904-9mta0aem	412	13	escape	escape	VB
cord-322904-9mta0aem	412	14	the	the	DT
cord-322904-9mta0aem	412	15	ER	er	NN
cord-322904-9mta0aem	413	1	but	but	CC
cord-322904-9mta0aem	413	2	this	this	DT
cord-322904-9mta0aem	413	3	has	have	VBZ
cord-322904-9mta0aem	413	4	not	not	RB
cord-322904-9mta0aem	413	5	been	be	VBN
cord-322904-9mta0aem	413	6	formally	formally	RB
cord-322904-9mta0aem	413	7	demonstrated	demonstrate	VBN
cord-322904-9mta0aem	413	8	.	.	.
cord-322904-9mta0aem	414	1	Early	early	JJ
cord-322904-9mta0aem	414	2	structural	structural	JJ
cord-322904-9mta0aem	414	3	studies	study	NNS
cord-322904-9mta0aem	414	4	on	on	IN
cord-322904-9mta0aem	414	5	mPyV	mPyV	NNP
cord-322904-9mta0aem	414	6	and	and	CC
cord-322904-9mta0aem	414	7	SV40	SV40	NNP
cord-322904-9mta0aem	414	8	challenged	challenge	VBD
cord-322904-9mta0aem	414	9	the	the	DT
cord-322904-9mta0aem	414	10	quasiequivalence	quasiequivalence	NN
cord-322904-9mta0aem	414	11	theory	theory	NN
cord-322904-9mta0aem	414	12	of	of	IN
cord-322904-9mta0aem	414	13	capsid	capsid	NNP
cord-322904-9mta0aem	414	14	assembly	assembly	NN
cord-322904-9mta0aem	414	15	as	as	IN
cord-322904-9mta0aem	414	16	there	there	EX
cord-322904-9mta0aem	414	17	were	be	VBD
cord-322904-9mta0aem	414	18	72	72	CD
cord-322904-9mta0aem	414	19	VP1	vp1	NN
cord-322904-9mta0aem	414	20	pentamers	pentamer	NNS
cord-322904-9mta0aem	414	21	arranged	arrange	VBD
cord-322904-9mta0aem	414	22	that	that	WDT
cord-322904-9mta0aem	414	23	formed	form	VBD
cord-322904-9mta0aem	414	24	both	both	DT
cord-322904-9mta0aem	414	25	pentavalent	pentavalent	JJ
cord-322904-9mta0aem	414	26	and	and	CC
cord-322904-9mta0aem	414	27	hexavalent	hexavalent	NN
cord-322904-9mta0aem	414	28	contacts	contact	NNS
cord-322904-9mta0aem	414	29	.	.	.
cord-322904-9mta0aem	415	1	Subsequent	subsequent	JJ
cord-322904-9mta0aem	415	2	high	high	JJ
cord-322904-9mta0aem	415	3	resolution	resolution	NN
cord-322904-9mta0aem	415	4	structural	structural	JJ
cord-322904-9mta0aem	415	5	studies	study	NNS
cord-322904-9mta0aem	415	6	provided	provide	VBD
cord-322904-9mta0aem	415	7	the	the	DT
cord-322904-9mta0aem	415	8	molecular	molecular	JJ
cord-322904-9mta0aem	415	9	basis	basis	NN
cord-322904-9mta0aem	415	10	for	for	IN
cord-322904-9mta0aem	415	11	this	this	DT
cord-322904-9mta0aem	415	12	unexpected	unexpected	JJ
cord-322904-9mta0aem	415	13	capsid	capsid	NN
cord-322904-9mta0aem	415	14	construction	construction	NN
cord-322904-9mta0aem	415	15	.	.	.
cord-322904-9mta0aem	416	1	It	-PRON-	PRP
cord-322904-9mta0aem	416	2	revealed	reveal	VBD
cord-322904-9mta0aem	416	3	that	that	IN
cord-322904-9mta0aem	416	4	the	the	DT
cord-322904-9mta0aem	416	5	interpentamer	interpentamer	NNP
cord-322904-9mta0aem	416	6	contacts	contact	NNS
cord-322904-9mta0aem	416	7	are	be	VBP
cord-322904-9mta0aem	416	8	primarily	primarily	RB
cord-322904-9mta0aem	416	9	mediated	mediate	VBN
cord-322904-9mta0aem	416	10	by	by	IN
cord-322904-9mta0aem	416	11	C	c	NN
cord-322904-9mta0aem	416	12	-	-	HYPH
cord-322904-9mta0aem	416	13	terminal	terminal	NN
cord-322904-9mta0aem	416	14	extensions	extension	NNS
cord-322904-9mta0aem	416	15	of	of	IN
cord-322904-9mta0aem	416	16	VP1	VP1	NNP
cord-322904-9mta0aem	416	17	,	,	,
cord-322904-9mta0aem	416	18	termed	termed	JJ
cord-322904-9mta0aem	416	19	arms	arm	NNS
cord-322904-9mta0aem	416	20	,	,	,
cord-322904-9mta0aem	416	21	that	that	WDT
cord-322904-9mta0aem	416	22	protrude	protrude	VBP
cord-322904-9mta0aem	416	23	in	in	IN
cord-322904-9mta0aem	416	24	different	different	JJ
cord-322904-9mta0aem	416	25	directions	direction	NNS
cord-322904-9mta0aem	416	26	from	from	IN
cord-322904-9mta0aem	416	27	each	each	DT
cord-322904-9mta0aem	416	28	VP1	vp1	NN
cord-322904-9mta0aem	416	29	monomer	monomer	NN
cord-322904-9mta0aem	416	30	and	and	CC
cord-322904-9mta0aem	416	31	contact	contact	NN
cord-322904-9mta0aem	416	32	neighboring	neighboring	NN
cord-322904-9mta0aem	416	33	pentamers	pentamer	NNS
cord-322904-9mta0aem	416	34	.	.	.
cord-322904-9mta0aem	417	1	Both	both	DT
cord-322904-9mta0aem	417	2	pentavalent	pentavalent	JJ
cord-322904-9mta0aem	417	3	and	and	CC
cord-322904-9mta0aem	417	4	hexavalent	hexavalent	NN
cord-322904-9mta0aem	417	5	pentamers	pentamer	NNS
cord-322904-9mta0aem	417	6	donate	donate	VBP
cord-322904-9mta0aem	417	7	and	and	CC
cord-322904-9mta0aem	417	8	accept	accept	VBP
cord-322904-9mta0aem	417	9	five	five	CD
cord-322904-9mta0aem	417	10	C	c	NN
cord-322904-9mta0aem	417	11	-	-	HYPH
cord-322904-9mta0aem	417	12	terminal	terminal	NN
cord-322904-9mta0aem	417	13	arms	arm	NNS
cord-322904-9mta0aem	417	14	to	to	TO
cord-322904-9mta0aem	417	15	tie	tie	VB
cord-322904-9mta0aem	417	16	the	the	DT
cord-322904-9mta0aem	417	17	capsid	capsid	NN
cord-322904-9mta0aem	417	18	together	together	RB
cord-322904-9mta0aem	417	19	.	.	.
cord-322904-9mta0aem	418	1	The	the	DT
cord-322904-9mta0aem	418	2	VP1	VP1	NNP
cord-322904-9mta0aem	418	3	pentamer	pentamer	NNP
cord-322904-9mta0aem	418	4	cores	core	NNS
cord-322904-9mta0aem	418	5	and	and	CC
cord-322904-9mta0aem	418	6	the	the	DT
cord-322904-9mta0aem	418	7	contacts	contact	NNS
cord-322904-9mta0aem	418	8	between	between	IN
cord-322904-9mta0aem	418	9	incoming	incoming	JJ
cord-322904-9mta0aem	418	10	arm	arm	NN
cord-322904-9mta0aem	418	11	and	and	CC
cord-322904-9mta0aem	418	12	acceptor	acceptor	NN
cord-322904-9mta0aem	418	13	monomer	monomer	NN
cord-322904-9mta0aem	418	14	are	be	VBP
cord-322904-9mta0aem	418	15	identical	identical	JJ
cord-322904-9mta0aem	418	16	throughout	throughout	IN
cord-322904-9mta0aem	418	17	the	the	DT
cord-322904-9mta0aem	418	18	capsid	capsid	NN
cord-322904-9mta0aem	418	19	,	,	,
cord-322904-9mta0aem	418	20	demonstrating	demonstrate	VBG
cord-322904-9mta0aem	418	21	that	that	IN
cord-322904-9mta0aem	418	22	the	the	DT
cord-322904-9mta0aem	418	23	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	418	24	capsid	capsid	NN
cord-322904-9mta0aem	418	25	also	also	RB
cord-322904-9mta0aem	418	26	uses	use	VBZ
cord-322904-9mta0aem	418	27	a	a	DT
cord-322904-9mta0aem	418	28	form	form	NN
cord-322904-9mta0aem	418	29	of	of	IN
cord-322904-9mta0aem	418	30	quasiequivalence	quasiequivalence	NN
cord-322904-9mta0aem	418	31	as	as	IN
cord-322904-9mta0aem	418	32	the	the	DT
cord-322904-9mta0aem	418	33	basis	basis	NN
cord-322904-9mta0aem	418	34	for	for	IN
cord-322904-9mta0aem	418	35	its	-PRON-	PRP$
cord-322904-9mta0aem	418	36	construction	construction	NN
cord-322904-9mta0aem	418	37	.	.	.
cord-322904-9mta0aem	419	1	Recent	recent	JJ
cord-322904-9mta0aem	419	2	high	high	JJ
cord-322904-9mta0aem	419	3	resolution	resolution	NN
cord-322904-9mta0aem	419	4	structural	structural	JJ
cord-322904-9mta0aem	419	5	studies	study	NNS
cord-322904-9mta0aem	419	6	on	on	IN
cord-322904-9mta0aem	419	7	viral	viral	JJ
cord-322904-9mta0aem	419	8	capsid	capsid	NN
cord-322904-9mta0aem	419	9	proteins	protein	NNS
cord-322904-9mta0aem	419	10	in	in	IN
cord-322904-9mta0aem	419	11	complex	complex	NN
cord-322904-9mta0aem	419	12	with	with	IN
cord-322904-9mta0aem	419	13	receptor	receptor	NN
cord-322904-9mta0aem	419	14	fragments	fragment	NNS
cord-322904-9mta0aem	419	15	has	have	VBZ
cord-322904-9mta0aem	419	16	provided	provide	VBN
cord-322904-9mta0aem	419	17	a	a	DT
cord-322904-9mta0aem	419	18	detailed	detailed	JJ
cord-322904-9mta0aem	419	19	picture	picture	NN
cord-322904-9mta0aem	419	20	of	of	IN
cord-322904-9mta0aem	419	21	how	how	WRB
cord-322904-9mta0aem	419	22	these	these	DT
cord-322904-9mta0aem	419	23	viruses	virus	NNS
cord-322904-9mta0aem	419	24	engage	engage	VBP
cord-322904-9mta0aem	419	25	this	this	DT
cord-322904-9mta0aem	419	26	component	component	NN
cord-322904-9mta0aem	419	27	of	of	IN
cord-322904-9mta0aem	419	28	the	the	DT
cord-322904-9mta0aem	419	29	receptor	receptor	NN
cord-322904-9mta0aem	419	30	complex	complex	NN
cord-322904-9mta0aem	419	31	.	.	.
cord-322904-9mta0aem	420	1	This	this	DT
cord-322904-9mta0aem	420	2	level	level	NN
cord-322904-9mta0aem	420	3	of	of	IN
cord-322904-9mta0aem	420	4	detail	detail	NN
cord-322904-9mta0aem	420	5	may	may	MD
cord-322904-9mta0aem	420	6	provide	provide	VB
cord-322904-9mta0aem	420	7	the	the	DT
cord-322904-9mta0aem	420	8	basis	basis	NN
cord-322904-9mta0aem	420	9	for	for	IN
cord-322904-9mta0aem	420	10	the	the	DT
cord-322904-9mta0aem	420	11	design	design	NN
cord-322904-9mta0aem	420	12	of	of	IN
cord-322904-9mta0aem	420	13	small	small	JJ
cord-322904-9mta0aem	420	14	molecular	molecular	JJ
cord-322904-9mta0aem	420	15	weight	weight	NN
cord-322904-9mta0aem	420	16	compounds	compound	NNS
cord-322904-9mta0aem	420	17	capable	capable	JJ
cord-322904-9mta0aem	420	18	of	of	IN
cord-322904-9mta0aem	420	19	antagonizing	antagonize	VBG
cord-322904-9mta0aem	420	20	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	420	21	host	host	NN
cord-322904-9mta0aem	420	22	cells	cell	NNS
cord-322904-9mta0aem	420	23	receptor	receptor	NN
cord-322904-9mta0aem	420	24	interactions	interaction	NNS
cord-322904-9mta0aem	420	25	and	and	CC
cord-322904-9mta0aem	420	26	may	may	MD
cord-322904-9mta0aem	420	27	in	in	IN
cord-322904-9mta0aem	420	28	time	time	NN
cord-322904-9mta0aem	420	29	lead	lead	VB
cord-322904-9mta0aem	420	30	to	to	IN
cord-322904-9mta0aem	420	31	novel	novel	JJ
cord-322904-9mta0aem	420	32	therapeutic	therapeutic	JJ
cord-322904-9mta0aem	420	33	approaches	approach	NNS
cord-322904-9mta0aem	420	34	to	to	TO
cord-322904-9mta0aem	420	35	treat	treat	VB
cord-322904-9mta0aem	420	36	patients	patient	NNS
cord-322904-9mta0aem	420	37	with	with	IN
cord-322904-9mta0aem	420	38	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	420	39	induced	induce	VBN
cord-322904-9mta0aem	420	40	disease	disease	NN
cord-322904-9mta0aem	420	41	.	.	.
cord-322904-9mta0aem	421	1	Bound	bind	VBN
cord-322904-9mta0aem	421	2	simian	simian	JJ
cord-322904-9mta0aem	421	3	virus	virus	NN
cord-322904-9mta0aem	421	4	40	40	CD
cord-322904-9mta0aem	421	5	translocates	translocate	NNS
cord-322904-9mta0aem	421	6	to	to	TO
cord-322904-9mta0aem	421	7	caveolin	caveolin	NNP
cord-322904-9mta0aem	421	8	enriched	enrich	VBN
cord-322904-9mta0aem	421	9	membrane	membrane	NN
cord-322904-9mta0aem	421	10	domains	domain	NNS
cord-322904-9mta0aem	421	11	,	,	,
cord-322904-9mta0aem	421	12	and	and	CC
cord-322904-9mta0aem	421	13	its	-PRON-	PRP$
cord-322904-9mta0aem	421	14	entry	entry	NN
cord-322904-9mta0aem	421	15	is	be	VBZ
cord-322904-9mta0aem	421	16	inhibited	inhibit	VBN
cord-322904-9mta0aem	421	17	by	by	IN
cord-322904-9mta0aem	421	18	drugs	drug	NNS
cord-322904-9mta0aem	421	19	that	that	WDT
cord-322904-9mta0aem	421	20	selectively	selectively	RB
cord-322904-9mta0aem	421	21	disrupt	disrupt	VBP
cord-322904-9mta0aem	421	22	caveolae	caveolae	NNP
cord-322904-9mta0aem	421	23	Class	class	NN
cord-322904-9mta0aem	421	24	I	i	IN
cord-322904-9mta0aem	421	25	major	major	JJ
cord-322904-9mta0aem	421	26	histocompatibility	histocompatibility	NN
cord-322904-9mta0aem	421	27	proteins	protein	NNS
cord-322904-9mta0aem	421	28	as	as	IN
cord-322904-9mta0aem	421	29	cell	cell	NN
cord-322904-9mta0aem	421	30	surface	surface	NN
cord-322904-9mta0aem	421	31	receptors	receptor	NNS
cord-322904-9mta0aem	421	32	for	for	IN
cord-322904-9mta0aem	421	33	simian	simian	JJ
cord-322904-9mta0aem	421	34	virus	virus	NN
cord-322904-9mta0aem	421	35	40	40	CD
cord-322904-9mta0aem	421	36	Discrimination	discrimination	NN
cord-322904-9mta0aem	421	37	between	between	IN
cord-322904-9mta0aem	421	38	sialic	sialic	JJ
cord-322904-9mta0aem	421	39	acid	acid	NN
cord-322904-9mta0aem	421	40	containing	contain	VBG
cord-322904-9mta0aem	421	41	receptors	receptor	NNS
cord-322904-9mta0aem	421	42	and	and	CC
cord-322904-9mta0aem	421	43	pseudoreceptors	pseudoreceptors	NNP
cord-322904-9mta0aem	421	44	regulates	regulate	VBZ
cord-322904-9mta0aem	421	45	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	421	46	spread	spread	VBD
cord-322904-9mta0aem	421	47	in	in	IN
cord-322904-9mta0aem	421	48	the	the	DT
cord-322904-9mta0aem	421	49	mouse	mouse	NN
cord-322904-9mta0aem	421	50	Insight	Insight	NNP
cord-322904-9mta0aem	421	51	into	into	IN
cord-322904-9mta0aem	421	52	host	host	NN
cord-322904-9mta0aem	421	53	cell	cell	NN
cord-322904-9mta0aem	421	54	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	421	55	-	-	HYPH
cord-322904-9mta0aem	421	56	recognition	recognition	NN
cord-322904-9mta0aem	421	57	by	by	IN
cord-322904-9mta0aem	421	58	human	human	JJ
cord-322904-9mta0aem	421	59	and	and	CC
cord-322904-9mta0aem	421	60	porcine	porcine	JJ
cord-322904-9mta0aem	421	61	rotavirus	rotavirus	NN
cord-322904-9mta0aem	421	62	from	from	IN
cord-322904-9mta0aem	421	63	crystal	crystal	JJ
cord-322904-9mta0aem	421	64	structures	structure	NNS
cord-322904-9mta0aem	421	65	of	of	IN
cord-322904-9mta0aem	421	66	the	the	DT
cord-322904-9mta0aem	421	67	virion	virion	NN
cord-322904-9mta0aem	421	68	spike	spike	NN
cord-322904-9mta0aem	421	69	associated	associate	VBD
cord-322904-9mta0aem	421	70	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	421	71	-	-	HYPH
cord-322904-9mta0aem	421	72	binding	bind	VBG
cord-322904-9mta0aem	421	73	domain	domain	NN
cord-322904-9mta0aem	421	74	(	(	-LRB-
cord-322904-9mta0aem	422	1	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	422	2	)	)	-RRB-
cord-322904-9mta0aem	422	3	Differences	difference	NNS
cord-322904-9mta0aem	422	4	in	in	IN
cord-322904-9mta0aem	422	5	the	the	DT
cord-322904-9mta0aem	422	6	sub	sub	NN
cord-322904-9mta0aem	422	7	-	-	NNS
cord-322904-9mta0aem	422	8	populations	population	NNS
cord-322904-9mta0aem	422	9	of	of	IN
cord-322904-9mta0aem	422	10	the	the	DT
cord-322904-9mta0aem	422	11	structural	structural	JJ
cord-322904-9mta0aem	422	12	proteins	protein	NNS
cord-322904-9mta0aem	422	13	of	of	IN
cord-322904-9mta0aem	422	14	polyoma	polyoma	NNP
cord-322904-9mta0aem	422	15	Differential	Differential	NNP
cord-322904-9mta0aem	422	16	adsorption	adsorption	NN
cord-322904-9mta0aem	422	17	of	of	IN
cord-322904-9mta0aem	422	18	polyoma	polyoma	NN
cord-322904-9mta0aem	422	19	virions	virion	NNS
cord-322904-9mta0aem	422	20	and	and	CC
cord-322904-9mta0aem	422	21	capsids	capsid	NNS
cord-322904-9mta0aem	422	22	to	to	TO
cord-322904-9mta0aem	422	23	mouse	mouse	VB
cord-322904-9mta0aem	422	24	kidney	kidney	NN
cord-322904-9mta0aem	422	25	cells	cell	NNS
cord-322904-9mta0aem	422	26	and	and	CC
cord-322904-9mta0aem	422	27	guinea	guinea	NN
cord-322904-9mta0aem	422	28	pig	pig	NN
cord-322904-9mta0aem	423	1	erythrocytes	erythrocyte	VBZ
cord-322904-9mta0aem	423	2	Crystal	Crystal	NNP
cord-322904-9mta0aem	423	3	structure	structure	NN
cord-322904-9mta0aem	423	4	of	of	IN
cord-322904-9mta0aem	423	5	species	specie	NNS
cord-322904-9mta0aem	423	6	D	d	NN
cord-322904-9mta0aem	423	7	adenovirus	adenovirus	NN
cord-322904-9mta0aem	423	8	fiber	fiber	NN
cord-322904-9mta0aem	423	9	knobs	knob	NNS
cord-322904-9mta0aem	423	10	and	and	CC
cord-322904-9mta0aem	423	11	their	-PRON-	PRP$
cord-322904-9mta0aem	423	12	sialic	sialic	JJ
cord-322904-9mta0aem	423	13	acid	acid	NN
cord-322904-9mta0aem	423	14	binding	bind	VBG
cord-322904-9mta0aem	423	15	sites	site	NNS
cord-322904-9mta0aem	423	16	Polyoma	Polyoma	NNP
cord-322904-9mta0aem	423	17	virus	virus	NN
cord-322904-9mta0aem	423	18	adsorbs	adsorb	VBZ
cord-322904-9mta0aem	423	19	to	to	IN
cord-322904-9mta0aem	423	20	specific	specific	JJ
cord-322904-9mta0aem	423	21	sialyloligosacccharide	sialyloligosacccharide	NN
cord-322904-9mta0aem	423	22	receptors	receptor	NNS
cord-322904-9mta0aem	423	23	on	on	IN
cord-322904-9mta0aem	423	24	erythrocytes	erythrocyte	NNS
cord-322904-9mta0aem	423	25	Sialyloligosaccharide	Sialyloligosaccharide	NNP
cord-322904-9mta0aem	423	26	receptors	receptor	NNS
cord-322904-9mta0aem	423	27	of	of	IN
cord-322904-9mta0aem	423	28	binding	bind	VBG
cord-322904-9mta0aem	423	29	variants	variant	NNS
cord-322904-9mta0aem	423	30	of	of	IN
cord-322904-9mta0aem	423	31	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	423	32	N	N	NNP
cord-322904-9mta0aem	423	33	-	-	HYPH
cord-322904-9mta0aem	423	34	glycolyl	glycolyl	NNP
cord-322904-9mta0aem	423	35	GM1	GM1	NNP
cord-322904-9mta0aem	423	36	ganglioside	ganglioside	NN
cord-322904-9mta0aem	423	37	as	as	IN
cord-322904-9mta0aem	423	38	a	a	DT
cord-322904-9mta0aem	423	39	receptor	receptor	NN
cord-322904-9mta0aem	423	40	for	for	IN
cord-322904-9mta0aem	423	41	simian	simian	JJ
cord-322904-9mta0aem	423	42	virus	virus	NN
cord-322904-9mta0aem	423	43	40	40	CD
cord-322904-9mta0aem	423	44	Alpha4beta1	alpha4beta1	NN
cord-322904-9mta0aem	423	45	integrin	integrin	NN
cord-322904-9mta0aem	423	46	acts	act	VBZ
cord-322904-9mta0aem	423	47	as	as	IN
cord-322904-9mta0aem	423	48	a	a	DT
cord-322904-9mta0aem	423	49	cell	cell	NN
cord-322904-9mta0aem	423	50	receptor	receptor	NN
cord-322904-9mta0aem	423	51	for	for	IN
cord-322904-9mta0aem	423	52	murine	murine	JJ
cord-322904-9mta0aem	423	53	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	423	54	at	at	IN
cord-322904-9mta0aem	423	55	the	the	DT
cord-322904-9mta0aem	423	56	postattachment	postattachment	JJ
cord-322904-9mta0aem	423	57	level	level	NN
cord-322904-9mta0aem	423	58	Mutation	Mutation	NNP
cord-322904-9mta0aem	423	59	in	in	IN
cord-322904-9mta0aem	423	60	the	the	DT
cord-322904-9mta0aem	423	61	VP1-LDV	VP1-LDV	NNP
cord-322904-9mta0aem	423	62	motif	motif	NN
cord-322904-9mta0aem	423	63	of	of	IN
cord-322904-9mta0aem	423	64	the	the	DT
cord-322904-9mta0aem	423	65	murine	murine	JJ
cord-322904-9mta0aem	423	66	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	423	67	affects	affect	VBZ
cord-322904-9mta0aem	423	68	viral	viral	JJ
cord-322904-9mta0aem	423	69	infectivity	infectivity	NN
cord-322904-9mta0aem	423	70	and	and	CC
cord-322904-9mta0aem	423	71	conditions	condition	NNS
cord-322904-9mta0aem	423	72	virus	virus	NN
cord-322904-9mta0aem	423	73	tissue	tissue	NN
cord-322904-9mta0aem	423	74	tropism	tropism	NN
cord-322904-9mta0aem	423	75	in	in	IN
cord-322904-9mta0aem	423	76	vivo	vivo	NNP
cord-322904-9mta0aem	423	77	Physical	physical	JJ
cord-322904-9mta0aem	423	78	principles	principle	NNS
cord-322904-9mta0aem	423	79	in	in	IN
cord-322904-9mta0aem	423	80	the	the	DT
cord-322904-9mta0aem	423	81	construction	construction	NN
cord-322904-9mta0aem	423	82	of	of	IN
cord-322904-9mta0aem	423	83	regular	regular	JJ
cord-322904-9mta0aem	423	84	viruses	virus	NNS
cord-322904-9mta0aem	423	85	Glycan	glycan	JJ
cord-322904-9mta0aem	423	86	topology	topology	NN
cord-322904-9mta0aem	423	87	determines	determine	VBZ
cord-322904-9mta0aem	423	88	human	human	JJ
cord-322904-9mta0aem	423	89	adaptation	adaptation	NN
cord-322904-9mta0aem	423	90	of	of	IN
cord-322904-9mta0aem	423	91	avian	avian	JJ
cord-322904-9mta0aem	423	92	H5N1	H5N1	NNP
cord-322904-9mta0aem	423	93	virus	virus	NN
cord-322904-9mta0aem	423	94	hemagglutinin	hemagglutinin	VBN
cord-322904-9mta0aem	423	95	Polyomavirus	Polyomavirus	NNP
cord-322904-9mta0aem	423	96	JC	JC	NNP
cord-322904-9mta0aem	423	97	infects	infect	VBZ
cord-322904-9mta0aem	423	98	human	human	JJ
cord-322904-9mta0aem	423	99	brain	brain	NN
cord-322904-9mta0aem	423	100	microvascular	microvascular	NN
cord-322904-9mta0aem	423	101	endothelial	endothelial	JJ
cord-322904-9mta0aem	423	102	cells	cell	NNS
cord-322904-9mta0aem	423	103	independent	independent	JJ
cord-322904-9mta0aem	423	104	of	of	IN
cord-322904-9mta0aem	424	1	serotonin	serotonin	NNP
cord-322904-9mta0aem	424	2	receptor	receptor	NN
cord-322904-9mta0aem	424	3	2A	2A	NNP
cord-322904-9mta0aem	424	4	Construction	Construction	NNP
cord-322904-9mta0aem	424	5	of	of	IN
cord-322904-9mta0aem	424	6	a	a	DT
cord-322904-9mta0aem	424	7	novel	novel	JJ
cord-322904-9mta0aem	424	8	JCV	JCV	NNP
cord-322904-9mta0aem	424	9	/	/	SYM
cord-322904-9mta0aem	424	10	SV40	SV40	NNP
cord-322904-9mta0aem	424	11	hybrid	hybrid	NN
cord-322904-9mta0aem	424	12	virus	virus	NN
cord-322904-9mta0aem	424	13	(	(	-LRB-
cord-322904-9mta0aem	424	14	JCSV	JCSV	NNP
cord-322904-9mta0aem	424	15	)	)	-RRB-
cord-322904-9mta0aem	424	16	reveals	reveal	VBZ
cord-322904-9mta0aem	424	17	a	a	DT
cord-322904-9mta0aem	424	18	role	role	NN
cord-322904-9mta0aem	424	19	for	for	IN
cord-322904-9mta0aem	424	20	the	the	DT
cord-322904-9mta0aem	424	21	JCV	JCV	NNP
cord-322904-9mta0aem	424	22	capsid	capsid	NN
cord-322904-9mta0aem	424	23	in	in	IN
cord-322904-9mta0aem	424	24	viral	viral	JJ
cord-322904-9mta0aem	424	25	tropism	tropism	NN
cord-322904-9mta0aem	424	26	Characterization	characterization	NN
cord-322904-9mta0aem	424	27	of	of	IN
cord-322904-9mta0aem	424	28	simian	simian	JJ
cord-322904-9mta0aem	424	29	virus	virus	NN
cord-322904-9mta0aem	424	30	40	40	CD
cord-322904-9mta0aem	424	31	receptor	receptor	NN
cord-322904-9mta0aem	424	32	moieties	moiety	NNS
cord-322904-9mta0aem	424	33	on	on	IN
cord-322904-9mta0aem	424	34	the	the	DT
cord-322904-9mta0aem	424	35	surfaces	surface	NNS
cord-322904-9mta0aem	424	36	of	of	IN
cord-322904-9mta0aem	424	37	Vero	Vero	NNP
cord-322904-9mta0aem	424	38	C1008	C1008	NNP
cord-322904-9mta0aem	424	39	cells	cell	NNS
cord-322904-9mta0aem	424	40	Crystal	Crystal	NNP
cord-322904-9mta0aem	424	41	structure	structure	NN
cord-322904-9mta0aem	424	42	of	of	IN
cord-322904-9mta0aem	424	43	the	the	DT
cord-322904-9mta0aem	424	44	multifunctional	multifunctional	JJ
cord-322904-9mta0aem	424	45	paramyxovirus	paramyxovirus	JJ
cord-322904-9mta0aem	424	46	hemagglutinin	hemagglutinin	NN
cord-322904-9mta0aem	424	47	-	-	:
cord-322904-9mta0aem	424	48	neuraminidase	neuraminidase	NN
cord-322904-9mta0aem	424	49	Structure	Structure	NNP
cord-322904-9mta0aem	424	50	of	of	IN
cord-322904-9mta0aem	424	51	small	small	JJ
cord-322904-9mta0aem	424	52	viruses	virus	NNS
cord-322904-9mta0aem	425	1	Some	some	DT
cord-322904-9mta0aem	425	2	characteristics	characteristic	NNS
cord-322904-9mta0aem	425	3	of	of	IN
cord-322904-9mta0aem	425	4	large	large	JJ
cord-322904-9mta0aem	425	5	plaque	plaque	NN
cord-322904-9mta0aem	425	6	and	and	CC
cord-322904-9mta0aem	425	7	small	small	JJ
cord-322904-9mta0aem	425	8	plaque	plaque	NN
cord-322904-9mta0aem	425	9	lines	line	NNS
cord-322904-9mta0aem	425	10	of	of	IN
cord-322904-9mta0aem	425	11	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	425	12	Specificity	Specificity	NNP
cord-322904-9mta0aem	425	13	and	and	CC
cord-322904-9mta0aem	425	14	affinity	affinity	NN
cord-322904-9mta0aem	425	15	of	of	IN
cord-322904-9mta0aem	425	16	sialic	sialic	JJ
cord-322904-9mta0aem	425	17	acid	acid	NN
cord-322904-9mta0aem	425	18	binding	bind	VBG
cord-322904-9mta0aem	425	19	by	by	IN
cord-322904-9mta0aem	425	20	the	the	DT
cord-322904-9mta0aem	425	21	rhesus	rhesus	NN
cord-322904-9mta0aem	425	22	rotavirus	rotavirus	NN
cord-322904-9mta0aem	425	23	VP8⁎	VP8⁎	NNP
cord-322904-9mta0aem	425	24	core	core	NN
cord-322904-9mta0aem	426	1	The	the	DT
cord-322904-9mta0aem	426	2	rhesus	rhesu	NNS
cord-322904-9mta0aem	426	3	rotavirus	rotavirus	VBP
cord-322904-9mta0aem	426	4	VP4	vp4	JJ
cord-322904-9mta0aem	426	5	sialic	sialic	NN
cord-322904-9mta0aem	426	6	acid	acid	NN
cord-322904-9mta0aem	426	7	binding	bind	VBG
cord-322904-9mta0aem	426	8	domain	domain	NN
cord-322904-9mta0aem	426	9	has	have	VBZ
cord-322904-9mta0aem	426	10	a	a	DT
cord-322904-9mta0aem	426	11	galectin	galectin	XX
cord-322904-9mta0aem	426	12	fold	fold	VB
cord-322904-9mta0aem	426	13	with	with	IN
cord-322904-9mta0aem	426	14	a	a	DT
cord-322904-9mta0aem	426	15	novel	novel	JJ
cord-322904-9mta0aem	426	16	carbohydrate	carbohydrate	NN
cord-322904-9mta0aem	426	17	binding	bind	VBG
cord-322904-9mta0aem	426	18	site	site	NN
cord-322904-9mta0aem	426	19	Polyomavirus	Polyomavirus	NNP
cord-322904-9mta0aem	426	20	replication	replication	NN
cord-322904-9mta0aem	426	21	in	in	IN
cord-322904-9mta0aem	426	22	mice	mouse	NNS
cord-322904-9mta0aem	426	23	:	:	:
cord-322904-9mta0aem	426	24	Influences	influence	NNS
cord-322904-9mta0aem	426	25	of	of	IN
cord-322904-9mta0aem	426	26	VP1	vp1	NN
cord-322904-9mta0aem	426	27	type	type	NN
cord-322904-9mta0aem	426	28	and	and	CC
cord-322904-9mta0aem	426	29	route	route	NN
cord-322904-9mta0aem	426	30	of	of	IN
cord-322904-9mta0aem	426	31	innoculation	innoculation	NN
cord-322904-9mta0aem	427	1	An	an	DT
cord-322904-9mta0aem	427	2	N	n	NN
cord-322904-9mta0aem	427	3	-	-	HYPH
cord-322904-9mta0aem	427	4	linked	link	VBN
cord-322904-9mta0aem	427	5	glycoprotein	glycoprotein	NN
cord-322904-9mta0aem	427	6	with	with	IN
cord-322904-9mta0aem	427	7	alpha	alpha	NN
cord-322904-9mta0aem	427	8	(	(	-LRB-
cord-322904-9mta0aem	427	9	2,3)-linked	2,3)-linked	CD
cord-322904-9mta0aem	427	10	sialic	sialic	JJ
cord-322904-9mta0aem	427	11	acid	acid	NN
cord-322904-9mta0aem	427	12	is	be	VBZ
cord-322904-9mta0aem	427	13	a	a	DT
cord-322904-9mta0aem	427	14	receptor	receptor	NN
cord-322904-9mta0aem	427	15	for	for	IN
cord-322904-9mta0aem	427	16	BK	BK	NNP
cord-322904-9mta0aem	427	17	Virus	Virus	NNP
cord-322904-9mta0aem	427	18	Direct	direct	JJ
cord-322904-9mta0aem	427	19	correlation	correlation	NN
cord-322904-9mta0aem	427	20	between	between	IN
cord-322904-9mta0aem	427	21	sialic	sialic	JJ
cord-322904-9mta0aem	427	22	acid	acid	NN
cord-322904-9mta0aem	427	23	binding	binding	NN
cord-322904-9mta0aem	427	24	and	and	CC
cord-322904-9mta0aem	427	25	infection	infection	NN
cord-322904-9mta0aem	427	26	of	of	IN
cord-322904-9mta0aem	427	27	cells	cell	NNS
cord-322904-9mta0aem	427	28	by	by	IN
cord-322904-9mta0aem	427	29	two	two	CD
cord-322904-9mta0aem	427	30	human	human	JJ
cord-322904-9mta0aem	427	31	polyomaviruses	polyomaviruse	NNS
cord-322904-9mta0aem	427	32	(	(	-LRB-
cord-322904-9mta0aem	427	33	Jcv	Jcv	NNP
cord-322904-9mta0aem	427	34	and	and	CC
cord-322904-9mta0aem	427	35	Bkv	Bkv	NNP
cord-322904-9mta0aem	427	36	)	)	-RRB-
cord-322904-9mta0aem	427	37	Infection	infection	NN
cord-322904-9mta0aem	427	38	of	of	IN
cord-322904-9mta0aem	427	39	Vero	Vero	NNP
cord-322904-9mta0aem	427	40	cells	cell	NNS
cord-322904-9mta0aem	427	41	by	by	IN
cord-322904-9mta0aem	427	42	BK	BK	NNP
cord-322904-9mta0aem	427	43	Virus	Virus	NNP
cord-322904-9mta0aem	427	44	is	be	VBZ
cord-322904-9mta0aem	427	45	dependent	dependent	JJ
cord-322904-9mta0aem	427	46	on	on	IN
cord-322904-9mta0aem	427	47	caveolae	caveolae	NNP
cord-322904-9mta0aem	427	48	Neoplasms	Neoplasms	NNP
cord-322904-9mta0aem	427	49	in	in	IN
cord-322904-9mta0aem	427	50	hamsters	hamster	NNS
cord-322904-9mta0aem	427	51	induced	induce	VBN
cord-322904-9mta0aem	427	52	by	by	IN
cord-322904-9mta0aem	427	53	mouse	mouse	NN
cord-322904-9mta0aem	427	54	tumor	tumor	NN
cord-322904-9mta0aem	427	55	agent	agent	NN
cord-322904-9mta0aem	427	56	passed	pass	VBD
cord-322904-9mta0aem	427	57	in	in	IN
cord-322904-9mta0aem	427	58	tissue	tissue	NN
cord-322904-9mta0aem	427	59	culture	culture	NN
cord-322904-9mta0aem	427	60	Binding	binding	NN
cord-322904-9mta0aem	427	61	of	of	IN
cord-322904-9mta0aem	427	62	the	the	DT
cord-322904-9mta0aem	427	63	influenza	influenza	NN
cord-322904-9mta0aem	427	64	A	a	DT
cord-322904-9mta0aem	427	65	virus	virus	NN
cord-322904-9mta0aem	427	66	to	to	IN
cord-322904-9mta0aem	427	67	cell	cell	NN
cord-322904-9mta0aem	427	68	-	-	HYPH
cord-322904-9mta0aem	427	69	surface	surface	NN
cord-322904-9mta0aem	427	70	receptors	receptor	NNS
cord-322904-9mta0aem	427	71	:	:	:
cord-322904-9mta0aem	427	72	structures	structure	NNS
cord-322904-9mta0aem	427	73	of	of	IN
cord-322904-9mta0aem	427	74	five	five	CD
cord-322904-9mta0aem	427	75	hemagglutinin	hemagglutinin	NN
cord-322904-9mta0aem	427	76	-	-	HYPH
cord-322904-9mta0aem	427	77	sialyloligosaccharide	sialyloligosaccharide	NN
cord-322904-9mta0aem	427	78	complexes	complex	NNS
cord-322904-9mta0aem	427	79	determined	determine	VBN
cord-322904-9mta0aem	427	80	by	by	IN
cord-322904-9mta0aem	427	81	X	x	NN
cord-322904-9mta0aem	427	82	-	-	NN
cord-322904-9mta0aem	427	83	ray	ray	NN
cord-322904-9mta0aem	427	84	crystallography	crystallography	NN
cord-322904-9mta0aem	427	85	Regulation	regulation	NN
cord-322904-9mta0aem	427	86	of	of	IN
cord-322904-9mta0aem	427	87	the	the	DT
cord-322904-9mta0aem	427	88	host	host	NN
cord-322904-9mta0aem	427	89	range	range	NN
cord-322904-9mta0aem	427	90	of	of	IN
cord-322904-9mta0aem	427	91	human	human	JJ
cord-322904-9mta0aem	427	92	papovavirus	papovavirus	NN
cord-322904-9mta0aem	427	93	JCV	JCV	NNP
cord-322904-9mta0aem	428	1	The	the	DT
cord-322904-9mta0aem	428	2	surface	surface	NN
cord-322904-9mta0aem	428	3	structure	structure	NN
cord-322904-9mta0aem	428	4	of	of	IN
cord-322904-9mta0aem	428	5	polyoma	polyoma	NNP
cord-322904-9mta0aem	428	6	virus	virus	NN
cord-322904-9mta0aem	429	1	The	the	DT
cord-322904-9mta0aem	429	2	human	human	JJ
cord-322904-9mta0aem	429	3	polyomavirus	polyomavirus	NN
cord-322904-9mta0aem	429	4	,	,	,
cord-322904-9mta0aem	429	5	JCV	JCV	NNP
cord-322904-9mta0aem	429	6	,	,	,
cord-322904-9mta0aem	429	7	uses	use	VBZ
cord-322904-9mta0aem	429	8	serotonin	serotonin	NN
cord-322904-9mta0aem	429	9	receptors	receptor	NNS
cord-322904-9mta0aem	429	10	to	to	TO
cord-322904-9mta0aem	429	11	infect	infect	VB
cord-322904-9mta0aem	429	12	cells	cell	NNS
cord-322904-9mta0aem	430	1	The	the	DT
cord-322904-9mta0aem	430	2	crystal	crystal	JJ
cord-322904-9mta0aem	430	3	structure	structure	NN
cord-322904-9mta0aem	430	4	of	of	IN
cord-322904-9mta0aem	430	5	tetanus	tetanus	NN
cord-322904-9mta0aem	430	6	toxin	toxin	NN
cord-322904-9mta0aem	430	7	Hc	Hc	NNP
cord-322904-9mta0aem	430	8	fragment	fragment	NN
cord-322904-9mta0aem	430	9	complexed	complexe	VBN
cord-322904-9mta0aem	430	10	with	with	IN
cord-322904-9mta0aem	430	11	a	a	DT
cord-322904-9mta0aem	430	12	synthetic	synthetic	JJ
cord-322904-9mta0aem	430	13	GT1b	GT1b	NNP
cord-322904-9mta0aem	430	14	analogue	analogue	NN
cord-322904-9mta0aem	430	15	suggests	suggest	VBZ
cord-322904-9mta0aem	430	16	cross	cross	NN
cord-322904-9mta0aem	430	17	-	-	JJ
cord-322904-9mta0aem	430	18	linking	link	VBG
cord-322904-9mta0aem	430	19	between	between	IN
cord-322904-9mta0aem	430	20	ganglioside	ganglioside	NN
cord-322904-9mta0aem	430	21	receptors	receptor	NNS
cord-322904-9mta0aem	430	22	and	and	CC
cord-322904-9mta0aem	430	23	the	the	DT
cord-322904-9mta0aem	430	24	toxin	toxin	NN
cord-322904-9mta0aem	430	25	Polyomavirus	Polyomavirus	NNP
cord-322904-9mta0aem	430	26	tumor	tumor	NN
cord-322904-9mta0aem	430	27	induction	induction	NN
cord-322904-9mta0aem	430	28	in	in	IN
cord-322904-9mta0aem	430	29	mice	mouse	NNS
cord-322904-9mta0aem	430	30	,	,	,
cord-322904-9mta0aem	430	31	effects	effect	NNS
cord-322904-9mta0aem	430	32	of	of	IN
cord-322904-9mta0aem	430	33	polymorphisms	polymorphism	NNS
cord-322904-9mta0aem	430	34	of	of	IN
cord-322904-9mta0aem	430	35	VP1	vp1	NN
cord-322904-9mta0aem	430	36	and	and	CC
cord-322904-9mta0aem	430	37	large	large	JJ
cord-322904-9mta0aem	430	38	T	t	NN
cord-322904-9mta0aem	430	39	antigen	antigen	NN
cord-322904-9mta0aem	430	40	A	a	DT
cord-322904-9mta0aem	430	41	single	single	JJ
cord-322904-9mta0aem	430	42	amino	amino	NN
cord-322904-9mta0aem	430	43	acid	acid	NN
cord-322904-9mta0aem	430	44	substitution	substitution	NN
cord-322904-9mta0aem	430	45	in	in	IN
cord-322904-9mta0aem	430	46	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	430	47	VP1	VP1	NNP
cord-322904-9mta0aem	430	48	correlates	correlate	VBZ
cord-322904-9mta0aem	430	49	with	with	IN
cord-322904-9mta0aem	430	50	plaque	plaque	NN
cord-322904-9mta0aem	430	51	size	size	NN
cord-322904-9mta0aem	430	52	and	and	CC
cord-322904-9mta0aem	430	53	hemagglutination	hemagglutination	NN
cord-322904-9mta0aem	430	54	behavior	behavior	NN
cord-322904-9mta0aem	431	1	Polyoma	polyoma	NN
cord-322904-9mta0aem	431	2	virus	virus	NN
cord-322904-9mta0aem	431	3	recognizes	recognize	VBZ
cord-322904-9mta0aem	431	4	specific	specific	JJ
cord-322904-9mta0aem	431	5	sialyloligosaccharide	sialyloligosaccharide	NNP
cord-322904-9mta0aem	431	6	receptors	receptor	NNS
cord-322904-9mta0aem	431	7	on	on	IN
cord-322904-9mta0aem	431	8	host	host	NN
cord-322904-9mta0aem	431	9	cells	cell	NNS
cord-322904-9mta0aem	432	1	The	the	DT
cord-322904-9mta0aem	432	2	structure	structure	NN
cord-322904-9mta0aem	432	3	and	and	CC
cord-322904-9mta0aem	432	4	receptor	receptor	NN
cord-322904-9mta0aem	432	5	binding	bind	VBG
cord-322904-9mta0aem	432	6	properties	property	NNS
cord-322904-9mta0aem	432	7	of	of	IN
cord-322904-9mta0aem	432	8	the	the	DT
cord-322904-9mta0aem	432	9	1918	1918	CD
cord-322904-9mta0aem	432	10	influenza	influenza	NN
cord-322904-9mta0aem	432	11	hemagglutinin	hemagglutinin	VBN
cord-322904-9mta0aem	432	12	New	New	NNP
cord-322904-9mta0aem	432	13	human	human	JJ
cord-322904-9mta0aem	432	14	papovavirus	papovavirus	NN
cord-322904-9mta0aem	432	15	(	(	-LRB-
cord-322904-9mta0aem	432	16	BK	BK	NNP
cord-322904-9mta0aem	432	17	)	)	-RRB-
cord-322904-9mta0aem	432	18	isolated	isolate	VBN
cord-322904-9mta0aem	432	19	from	from	IN
cord-322904-9mta0aem	432	20	urine	urine	NN
cord-322904-9mta0aem	432	21	after	after	IN
cord-322904-9mta0aem	432	22	renal	renal	JJ
cord-322904-9mta0aem	432	23	transplantation	transplantation	NN
cord-322904-9mta0aem	432	24	Uptake	Uptake	NNP
cord-322904-9mta0aem	432	25	pathway	pathway	NN
cord-322904-9mta0aem	432	26	of	of	IN
cord-322904-9mta0aem	432	27	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	432	28	via	via	IN
cord-322904-9mta0aem	432	29	ganglioside	ganglioside	NN
cord-322904-9mta0aem	432	30	GD1a	GD1a	NNP
cord-322904-9mta0aem	432	31	Ganglioside	Ganglioside	NNP
cord-322904-9mta0aem	432	32	GD1a	GD1a	NNP
cord-322904-9mta0aem	432	33	restores	restore	VBZ
cord-322904-9mta0aem	432	34	infectibility	infectibility	NN
cord-322904-9mta0aem	432	35	to	to	IN
cord-322904-9mta0aem	432	36	mouse	mouse	NN
cord-322904-9mta0aem	432	37	cells	cell	NNS
cord-322904-9mta0aem	432	38	lacking	lack	VBG
cord-322904-9mta0aem	432	39	functional	functional	JJ
cord-322904-9mta0aem	432	40	receptors	receptor	NNS
cord-322904-9mta0aem	432	41	for	for	IN
cord-322904-9mta0aem	432	42	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	432	43	Development	Development	NNP
cord-322904-9mta0aem	432	44	of	of	IN
cord-322904-9mta0aem	432	45	tumors	tumor	NNS
cord-322904-9mta0aem	432	46	in	in	IN
cord-322904-9mta0aem	432	47	hamsters	hamster	NNS
cord-322904-9mta0aem	432	48	inoculated	inoculate	VBN
cord-322904-9mta0aem	432	49	in	in	IN
cord-322904-9mta0aem	432	50	the	the	DT
cord-322904-9mta0aem	432	51	neonatal	neonatal	JJ
cord-322904-9mta0aem	432	52	period	period	NN
cord-322904-9mta0aem	432	53	with	with	IN
cord-322904-9mta0aem	432	54	vacuolating	vacuolating	NN
cord-322904-9mta0aem	432	55	virus	virus	NN
cord-322904-9mta0aem	432	56	,	,	,
cord-322904-9mta0aem	432	57	SV-40	SV-40	NNP
cord-322904-9mta0aem	432	58	Neck	Neck	NNP
cord-322904-9mta0aem	432	59	tumors	tumor	NNS
cord-322904-9mta0aem	432	60	,	,	,
cord-322904-9mta0aem	432	61	or	or	CC
cord-322904-9mta0aem	432	62	leukemia	leukemia	NN
cord-322904-9mta0aem	432	63	,	,	,
cord-322904-9mta0aem	432	64	developing	develop	VBG
cord-322904-9mta0aem	432	65	in	in	IN
cord-322904-9mta0aem	432	66	adult	adult	NN
cord-322904-9mta0aem	432	67	C3H	c3h	JJ
cord-322904-9mta0aem	432	68	mice	mice	NN
cord-322904-9mta0aem	432	69	following	follow	VBG
cord-322904-9mta0aem	432	70	inoculation	inoculation	NN
cord-322904-9mta0aem	432	71	,	,	,
cord-322904-9mta0aem	432	72	in	in	IN
cord-322904-9mta0aem	432	73	early	early	JJ
cord-322904-9mta0aem	432	74	infancy	infancy	NN
cord-322904-9mta0aem	432	75	,	,	,
cord-322904-9mta0aem	432	76	with	with	IN
cord-322904-9mta0aem	432	77	filtered	filter	VBN
cord-322904-9mta0aem	432	78	(	(	-LRB-
cord-322904-9mta0aem	432	79	Berkefeld	Berkefeld	NNP
cord-322904-9mta0aem	432	80	N	N	NNP
cord-322904-9mta0aem	432	81	)	)	-RRB-
cord-322904-9mta0aem	432	82	,	,	,
cord-322904-9mta0aem	432	83	or	or	CC
cord-322904-9mta0aem	432	84	centrifugated	centrifugated	NNP
cord-322904-9mta0aem	432	85	(	(	-LRB-
cord-322904-9mta0aem	432	86	144,000	144,000	CD
cord-322904-9mta0aem	432	87	×g	×g	JJ
cord-322904-9mta0aem	432	88	)	)	-RRB-
cord-322904-9mta0aem	432	89	,	,	,
cord-322904-9mta0aem	432	90	Ak	Ak	NNP
cord-322904-9mta0aem	432	91	-	-	HYPH
cord-322904-9mta0aem	432	92	leukemic	leukemic	JJ
cord-322904-9mta0aem	432	93	extracts	extract	VBZ
cord-322904-9mta0aem	432	94	X	x	NN
cord-322904-9mta0aem	432	95	-	-	NN
cord-322904-9mta0aem	432	96	ray	ray	JJ
cord-322904-9mta0aem	432	97	structures	structure	NNS
cord-322904-9mta0aem	432	98	of	of	IN
cord-322904-9mta0aem	432	99	H5	h5	NN
cord-322904-9mta0aem	432	100	avian	avian	NN
cord-322904-9mta0aem	432	101	and	and	CC
cord-322904-9mta0aem	432	102	H9	H9	NNP
cord-322904-9mta0aem	432	103	swine	swine	NN
cord-322904-9mta0aem	432	104	influenza	influenza	NN
cord-322904-9mta0aem	432	105	virus	virus	NN
cord-322904-9mta0aem	432	106	hemagglutinins	hemagglutinin	NNS
cord-322904-9mta0aem	432	107	bound	bind	VBN
cord-322904-9mta0aem	432	108	to	to	IN
cord-322904-9mta0aem	432	109	avian	avian	JJ
cord-322904-9mta0aem	432	110	and	and	CC
cord-322904-9mta0aem	432	111	human	human	JJ
cord-322904-9mta0aem	432	112	receptor	receptor	NN
cord-322904-9mta0aem	432	113	analogs	analogs	NNP
cord-322904-9mta0aem	432	114	X	X	NNP
cord-322904-9mta0aem	432	115	-	-	NN
cord-322904-9mta0aem	432	116	ray	ray	JJ
cord-322904-9mta0aem	432	117	structure	structure	NN
cord-322904-9mta0aem	432	118	of	of	IN
cord-322904-9mta0aem	432	119	the	the	DT
cord-322904-9mta0aem	432	120	hemagglutinin	hemagglutinin	NN
cord-322904-9mta0aem	432	121	of	of	IN
cord-322904-9mta0aem	432	122	a	a	DT
cord-322904-9mta0aem	432	123	potential	potential	JJ
cord-322904-9mta0aem	432	124	H3	H3	NNP
cord-322904-9mta0aem	432	125	avian	avian	JJ
cord-322904-9mta0aem	432	126	progenitor	progenitor	NN
cord-322904-9mta0aem	432	127	of	of	IN
cord-322904-9mta0aem	432	128	the	the	DT
cord-322904-9mta0aem	432	129	1968	1968	CD
cord-322904-9mta0aem	432	130	Hong	Hong	NNP
cord-322904-9mta0aem	432	131	Kong	Kong	NNP
cord-322904-9mta0aem	432	132	pandemic	pandemic	NN
cord-322904-9mta0aem	432	133	influenza	influenza	NN
cord-322904-9mta0aem	432	134	virus	virus	NN
cord-322904-9mta0aem	432	135	In	in	IN
cord-322904-9mta0aem	432	136	and	and	CC
cord-322904-9mta0aem	432	137	out	out	IN
cord-322904-9mta0aem	432	138	of	of	IN
cord-322904-9mta0aem	432	139	the	the	DT
cord-322904-9mta0aem	432	140	ER	er	NN
cord-322904-9mta0aem	432	141	:	:	:
cord-322904-9mta0aem	432	142	protein	protein	NN
cord-322904-9mta0aem	432	143	folding	folding	NN
cord-322904-9mta0aem	432	144	,	,	,
cord-322904-9mta0aem	432	145	quality	quality	NN
cord-322904-9mta0aem	432	146	control	control	NN
cord-322904-9mta0aem	432	147	,	,	,
cord-322904-9mta0aem	432	148	degradation	degradation	NN
cord-322904-9mta0aem	432	149	,	,	,
cord-322904-9mta0aem	432	150	and	and	CC
cord-322904-9mta0aem	432	151	related	relate	VBN
cord-322904-9mta0aem	432	152	human	human	JJ
cord-322904-9mta0aem	432	153	diseases	disease	NNS
cord-322904-9mta0aem	433	1	Morphological	morphological	JJ
cord-322904-9mta0aem	433	2	aspects	aspect	NNS
cord-322904-9mta0aem	433	3	of	of	IN
cord-322904-9mta0aem	433	4	the	the	DT
cord-322904-9mta0aem	433	5	uptake	uptake	NN
cord-322904-9mta0aem	433	6	of	of	IN
cord-322904-9mta0aem	433	7	simian	simian	JJ
cord-322904-9mta0aem	433	8	virus	virus	NN
cord-322904-9mta0aem	433	9	40	40	CD
cord-322904-9mta0aem	433	10	by	by	IN
cord-322904-9mta0aem	433	11	permissive	permissive	JJ
cord-322904-9mta0aem	433	12	cells	cell	NNS
cord-322904-9mta0aem	433	13	Analysis	Analysis	NNP
cord-322904-9mta0aem	433	14	of	of	IN
cord-322904-9mta0aem	433	15	a	a	DT
cord-322904-9mta0aem	433	16	nuclear	nuclear	JJ
cord-322904-9mta0aem	433	17	localization	localization	NN
cord-322904-9mta0aem	433	18	signal	signal	NN
cord-322904-9mta0aem	433	19	of	of	IN
cord-322904-9mta0aem	433	20	simian	simian	JJ
cord-322904-9mta0aem	433	21	virus	virus	NN
cord-322904-9mta0aem	433	22	40	40	CD
cord-322904-9mta0aem	433	23	major	major	JJ
cord-322904-9mta0aem	433	24	capsid	capsid	NN
cord-322904-9mta0aem	433	25	protein	protein	NN
cord-322904-9mta0aem	433	26	Vp1	vp1	NN
cord-322904-9mta0aem	434	1	How	how	WRB
cord-322904-9mta0aem	434	2	do	do	VBP
cord-322904-9mta0aem	434	3	animal	animal	NN
cord-322904-9mta0aem	434	4	DNA	dna	NN
cord-322904-9mta0aem	434	5	viruses	virus	NNS
cord-322904-9mta0aem	434	6	get	get	VBP
cord-322904-9mta0aem	434	7	to	to	IN
cord-322904-9mta0aem	434	8	the	the	DT
cord-322904-9mta0aem	434	9	nucleus	nucleus	NN
cord-322904-9mta0aem	434	10	?	?	.
cord-322904-9mta0aem	435	1	424	424	CD
cord-322904-9mta0aem	435	2	-	-	SYM
cord-322904-9mta0aem	435	3	431	431	CD
cord-322904-9mta0aem	435	4	.	.	.
cord-322904-9mta0aem	436	1	the	the	DT
cord-322904-9mta0aem	436	2	manuscript	manuscript	NN
cord-322904-9mta0aem	436	3	entitled	entitle	VBN
cord-322904-9mta0aem	436	4	"	"	``
cord-322904-9mta0aem	436	5	Structure	Structure	NNP
cord-322904-9mta0aem	436	6	,	,	,
cord-322904-9mta0aem	436	7	attachment	attachment	NN
cord-322904-9mta0aem	436	8	and	and	CC
cord-322904-9mta0aem	436	9	entry	entry	NN
cord-322904-9mta0aem	436	10	of	of	IN
cord-322904-9mta0aem	436	11	polyoma	polyoma	NN
cord-322904-9mta0aem	436	12	-	-	HYPH
cord-322904-9mta0aem	436	13	and	and	CC
cord-322904-9mta0aem	436	14	papillomaviruses	papillomaviruse	VBZ
cord-322904-9mta0aem	436	15	Oligosaccharides	Oligosaccharides	NNP
cord-322904-9mta0aem	436	16	as	as	IN
cord-322904-9mta0aem	436	17	receptors	receptor	NNS
cord-322904-9mta0aem	436	18	for	for	IN
cord-322904-9mta0aem	436	19	JC	JC	NNP
cord-322904-9mta0aem	436	20	virus	virus	NN
cord-322904-9mta0aem	436	21	Structure	Structure	NNP
cord-322904-9mta0aem	436	22	of	of	IN
cord-322904-9mta0aem	436	23	simian	simian	JJ
cord-322904-9mta0aem	436	24	virus	virus	NN
cord-322904-9mta0aem	436	25	40	40	CD
cord-322904-9mta0aem	436	26	at	at	IN
cord-322904-9mta0aem	436	27	3.8	3.8	CD
cord-322904-9mta0aem	436	28	A	a	DT
cord-322904-9mta0aem	436	29	resolution	resolution	NN
cord-322904-9mta0aem	437	1	Murine	murine	JJ
cord-322904-9mta0aem	437	2	polyomavirus	polyomavirus	NN
cord-322904-9mta0aem	437	3	requires	require	VBZ
cord-322904-9mta0aem	437	4	the	the	DT
cord-322904-9mta0aem	437	5	endoplasmic	endoplasmic	NN
cord-322904-9mta0aem	437	6	reticulum	reticulum	NN
cord-322904-9mta0aem	437	7	protein	protein	NN
cord-322904-9mta0aem	437	8	Derlin-2	Derlin-2	NNP
cord-322904-9mta0aem	437	9	to	to	TO
cord-322904-9mta0aem	437	10	initiate	initiate	VB
cord-322904-9mta0aem	437	11	infection	infection	NN
cord-322904-9mta0aem	437	12	Infection	infection	NN
cord-322904-9mta0aem	437	13	of	of	IN
cord-322904-9mta0aem	437	14	glial	glial	JJ
cord-322904-9mta0aem	437	15	cells	cell	NNS
cord-322904-9mta0aem	437	16	by	by	IN
cord-322904-9mta0aem	437	17	the	the	DT
cord-322904-9mta0aem	437	18	human	human	JJ
cord-322904-9mta0aem	437	19	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	437	20	JC	JC	NNP
cord-322904-9mta0aem	437	21	is	be	VBZ
cord-322904-9mta0aem	437	22	mediated	mediate	VBN
cord-322904-9mta0aem	437	23	by	by	IN
cord-322904-9mta0aem	437	24	an	an	DT
cord-322904-9mta0aem	437	25	N	n	CD
cord-322904-9mta0aem	437	26	-	-	HYPH
cord-322904-9mta0aem	437	27	linked	link	VBN
cord-322904-9mta0aem	437	28	glycoprotein	glycoprotein	NN
cord-322904-9mta0aem	437	29	containing	contain	VBG
cord-322904-9mta0aem	437	30	terminal	terminal	JJ
cord-322904-9mta0aem	437	31	alpha	alpha	NNP
cord-322904-9mta0aem	437	32	2	2	CD
cord-322904-9mta0aem	437	33	-	-	SYM
cord-322904-9mta0aem	437	34	6	6	CD
cord-322904-9mta0aem	437	35	linked	link	VBN
cord-322904-9mta0aem	437	36	sialic	sialic	NN
cord-322904-9mta0aem	437	37	acids	acid	NNS
cord-322904-9mta0aem	437	38	Identification	identification	NN
cord-322904-9mta0aem	437	39	of	of	IN
cord-322904-9mta0aem	437	40	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	437	41	GD1b	GD1b	NNP
cord-322904-9mta0aem	437	42	and	and	CC
cord-322904-9mta0aem	437	43	GT1b	GT1b	NNP
cord-322904-9mta0aem	437	44	as	as	IN
cord-322904-9mta0aem	437	45	receptors	receptor	NNS
cord-322904-9mta0aem	437	46	for	for	IN
cord-322904-9mta0aem	437	47	BK	BK	NNP
cord-322904-9mta0aem	437	48	virus	virus	NN
cord-322904-9mta0aem	437	49	Factors	factor	NNS
cord-322904-9mta0aem	437	50	contributing	contribute	VBG
cord-322904-9mta0aem	437	51	to	to	IN
cord-322904-9mta0aem	437	52	the	the	DT
cord-322904-9mta0aem	437	53	restricted	restrict	VBN
cord-322904-9mta0aem	437	54	DNA	dna	NN
cord-322904-9mta0aem	437	55	replicating	replicate	VBG
cord-322904-9mta0aem	437	56	activity	activity	NN
cord-322904-9mta0aem	437	57	of	of	IN
cord-322904-9mta0aem	437	58	JC	JC	NNP
cord-322904-9mta0aem	437	59	Virus	Virus	NNP
cord-322904-9mta0aem	437	60	Early	early	JJ
cord-322904-9mta0aem	437	61	events	event	NNS
cord-322904-9mta0aem	437	62	in	in	IN
cord-322904-9mta0aem	437	63	polyoma	polyoma	NN
cord-322904-9mta0aem	437	64	virus	virus	NN
cord-322904-9mta0aem	437	65	infection	infection	NN
cord-322904-9mta0aem	437	66	:	:	:
cord-322904-9mta0aem	437	67	attachment	attachment	NN
cord-322904-9mta0aem	437	68	,	,	,
cord-322904-9mta0aem	437	69	penetration	penetration	NN
cord-322904-9mta0aem	437	70	,	,	,
cord-322904-9mta0aem	437	71	and	and	CC
cord-322904-9mta0aem	437	72	nuclear	nuclear	JJ
cord-322904-9mta0aem	437	73	entry	entry	NN
cord-322904-9mta0aem	437	74	ERp29	ERp29	NNS
cord-322904-9mta0aem	437	75	triggers	trigger	VBZ
cord-322904-9mta0aem	437	76	a	a	DT
cord-322904-9mta0aem	437	77	conformational	conformational	JJ
cord-322904-9mta0aem	437	78	change	change	NN
cord-322904-9mta0aem	437	79	in	in	IN
cord-322904-9mta0aem	437	80	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	437	81	to	to	TO
cord-322904-9mta0aem	437	82	stimulate	stimulate	VB
cord-322904-9mta0aem	437	83	membrane	membrane	NN
cord-322904-9mta0aem	437	84	binding	bind	VBG
cord-322904-9mta0aem	437	85	Production	production	NN
cord-322904-9mta0aem	437	86	and	and	CC
cord-322904-9mta0aem	437	87	characterization	characterization	NN
cord-322904-9mta0aem	437	88	of	of	IN
cord-322904-9mta0aem	437	89	monoclonal	monoclonal	JJ
cord-322904-9mta0aem	437	90	antibodies	antibody	NNS
cord-322904-9mta0aem	437	91	to	to	IN
cord-322904-9mta0aem	437	92	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	437	93	major	major	JJ
cord-322904-9mta0aem	437	94	capsid	capsid	NN
cord-322904-9mta0aem	437	95	protein	protein	NN
cord-322904-9mta0aem	437	96	VP1	VP1	NNP
cord-322904-9mta0aem	437	97	Anti	Anti	NNP
cord-322904-9mta0aem	437	98	-	-	JJ
cord-322904-9mta0aem	437	99	idiotypic	idiotypic	JJ
cord-322904-9mta0aem	437	100	antibodies	antibody	NNS
cord-322904-9mta0aem	437	101	to	to	IN
cord-322904-9mta0aem	437	102	a	a	DT
cord-322904-9mta0aem	437	103	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	437	104	monoclonal	monoclonal	JJ
cord-322904-9mta0aem	437	105	antibody	antibody	NN
cord-322904-9mta0aem	437	106	recognize	recognize	VB
cord-322904-9mta0aem	437	107	cell	cell	NN
cord-322904-9mta0aem	437	108	surface	surface	NN
cord-322904-9mta0aem	437	109	components	component	NNS
cord-322904-9mta0aem	437	110	of	of	IN
cord-322904-9mta0aem	437	111	mouse	mouse	NN
cord-322904-9mta0aem	437	112	kidney	kidney	NN
cord-322904-9mta0aem	437	113	cells	cell	NNS
cord-322904-9mta0aem	437	114	and	and	CC
cord-322904-9mta0aem	437	115	prevent	prevent	VB
cord-322904-9mta0aem	437	116	polyomavirus	polyomavirus	JJ
cord-322904-9mta0aem	437	117	infection	infection	NN
cord-322904-9mta0aem	437	118	Virus	Virus	NNP
cord-322904-9mta0aem	437	119	entry	entry	NN
cord-322904-9mta0aem	437	120	into	into	IN
cord-322904-9mta0aem	437	121	animal	animal	NN
cord-322904-9mta0aem	437	122	cells	cell	NNS
cord-322904-9mta0aem	437	123	Replication	replication	NN
cord-322904-9mta0aem	437	124	of	of	IN
cord-322904-9mta0aem	437	125	polyoma	polyoma	NN
cord-322904-9mta0aem	437	126	virus	virus	NN
cord-322904-9mta0aem	437	127	in	in	IN
cord-322904-9mta0aem	437	128	mouse	mouse	NN
cord-322904-9mta0aem	437	129	embryo	embryo	NN
cord-322904-9mta0aem	437	130	cells	cell	NNS
cord-322904-9mta0aem	437	131	:	:	:
cord-322904-9mta0aem	437	132	electron	electron	NN
cord-322904-9mta0aem	437	133	microscopic	microscopic	JJ
cord-322904-9mta0aem	437	134	observations	observation	NNS
cord-322904-9mta0aem	437	135	Electron	Electron	NNP
cord-322904-9mta0aem	437	136	microscopic	microscopic	JJ
cord-322904-9mta0aem	437	137	observations	observation	NNS
cord-322904-9mta0aem	437	138	on	on	IN
cord-322904-9mta0aem	437	139	multiple	multiple	JJ
cord-322904-9mta0aem	437	140	polyoma	polyoma	JJ
cord-322904-9mta0aem	437	141	virus	virus	NN
cord-322904-9mta0aem	437	142	-	-	HYPH
cord-322904-9mta0aem	437	143	related	relate	VBN
cord-322904-9mta0aem	437	144	particles	particle	NNS
cord-322904-9mta0aem	437	145	Membrane	membrane	NN
cord-322904-9mta0aem	437	146	fusion	fusion	NN
cord-322904-9mta0aem	437	147	as	as	IN
cord-322904-9mta0aem	437	148	a	a	DT
cord-322904-9mta0aem	437	149	mechanism	mechanism	NN
cord-322904-9mta0aem	437	150	for	for	IN
cord-322904-9mta0aem	437	151	simian	simian	JJ
cord-322904-9mta0aem	437	152	virus	virus	NN
cord-322904-9mta0aem	437	153	40	40	CD
cord-322904-9mta0aem	437	154	entry	entry	NN
cord-322904-9mta0aem	437	155	into	into	IN
cord-322904-9mta0aem	437	156	different	different	JJ
cord-322904-9mta0aem	437	157	cellular	cellular	JJ
cord-322904-9mta0aem	437	158	compartments	compartment	NNS
cord-322904-9mta0aem	437	159	Crystal	Crystal	NNP
cord-322904-9mta0aem	437	160	structure	structure	NN
cord-322904-9mta0aem	437	161	of	of	IN
cord-322904-9mta0aem	437	162	cholera	cholera	NN
cord-322904-9mta0aem	437	163	toxin	toxin	NN
cord-322904-9mta0aem	437	164	B	B	NNP
cord-322904-9mta0aem	437	165	-	-	HYPH
cord-322904-9mta0aem	437	166	pentamer	pentamer	NN
cord-322904-9mta0aem	437	167	bound	bind	VBN
cord-322904-9mta0aem	437	168	to	to	IN
cord-322904-9mta0aem	437	169	receptor	receptor	NN
cord-322904-9mta0aem	437	170	GM1	GM1	NNP
cord-322904-9mta0aem	437	171	pentasaccharide	pentasaccharide	NNP
cord-322904-9mta0aem	437	172	Biosynthesis	Biosynthesis	NNP
cord-322904-9mta0aem	437	173	and	and	CC
cord-322904-9mta0aem	437	174	localization	localization	NN
cord-322904-9mta0aem	437	175	of	of	IN
cord-322904-9mta0aem	437	176	gangliosides	ganglioside	NNS
cord-322904-9mta0aem	437	177	in	in	IN
cord-322904-9mta0aem	437	178	cultured	cultured	JJ
cord-322904-9mta0aem	437	179	cells	cell	NNS
cord-322904-9mta0aem	437	180	Association	Association	NNP
cord-322904-9mta0aem	437	181	with	with	IN
cord-322904-9mta0aem	437	182	capsid	capsid	NN
cord-322904-9mta0aem	437	183	proteins	protein	NNS
cord-322904-9mta0aem	437	184	promotes	promote	VBZ
cord-322904-9mta0aem	437	185	nuclear	nuclear	JJ
cord-322904-9mta0aem	437	186	targeting	targeting	NN
cord-322904-9mta0aem	437	187	of	of	IN
cord-322904-9mta0aem	437	188	simian	simian	JJ
cord-322904-9mta0aem	437	189	virus	virus	NN
cord-322904-9mta0aem	437	190	40	40	CD
cord-322904-9mta0aem	437	191	DNA	DNA	NNP
cord-322904-9mta0aem	437	192	Structural	structural	JJ
cord-322904-9mta0aem	437	193	basis	basis	NN
cord-322904-9mta0aem	437	194	of	of	IN
cord-322904-9mta0aem	437	195	GM1	GM1	NNP
cord-322904-9mta0aem	437	196	ganglioside	ganglioside	NN
cord-322904-9mta0aem	437	197	recognition	recognition	NN
cord-322904-9mta0aem	437	198	by	by	IN
cord-322904-9mta0aem	437	199	simian	simian	JJ
cord-322904-9mta0aem	437	200	virus	virus	NN
cord-322904-9mta0aem	437	201	40	40	CD
cord-322904-9mta0aem	437	202	Cultivation	cultivation	NN
cord-322904-9mta0aem	437	203	of	of	IN
cord-322904-9mta0aem	437	204	papovalike	papovalike	NN
cord-322904-9mta0aem	437	205	virus	virus	NN
cord-322904-9mta0aem	437	206	from	from	IN
cord-322904-9mta0aem	437	207	human	human	JJ
cord-322904-9mta0aem	437	208	brain	brain	NN
cord-322904-9mta0aem	437	209	with	with	IN
cord-322904-9mta0aem	437	210	progressive	progressive	JJ
cord-322904-9mta0aem	437	211	multifocal	multifocal	JJ
cord-322904-9mta0aem	437	212	leukoencephalopathy	leukoencephalopathy	NNP
cord-322904-9mta0aem	437	213	Caveolar	Caveolar	NNP
cord-322904-9mta0aem	437	214	endocytosis	endocytosis	NN
cord-322904-9mta0aem	437	215	of	of	IN
cord-322904-9mta0aem	437	216	simian	simian	JJ
cord-322904-9mta0aem	437	217	virus	virus	NN
cord-322904-9mta0aem	437	218	40	40	CD
cord-322904-9mta0aem	437	219	reveals	reveal	VBZ
cord-322904-9mta0aem	437	220	a	a	DT
cord-322904-9mta0aem	437	221	new	new	JJ
cord-322904-9mta0aem	437	222	two	two	CD
cord-322904-9mta0aem	437	223	-	-	HYPH
cord-322904-9mta0aem	437	224	step	step	NN
cord-322904-9mta0aem	437	225	vesicular	vesicular	JJ
cord-322904-9mta0aem	437	226	-	-	HYPH
cord-322904-9mta0aem	437	227	transport	transport	NN
cord-322904-9mta0aem	437	228	pathway	pathway	NN
cord-322904-9mta0aem	437	229	to	to	IN
cord-322904-9mta0aem	437	230	the	the	DT
cord-322904-9mta0aem	437	231	ER	ER	NNP
cord-322904-9mta0aem	437	232	JC	JC	NNP
cord-322904-9mta0aem	437	233	virus	virus	NN
cord-322904-9mta0aem	437	234	enters	enter	VBZ
cord-322904-9mta0aem	437	235	human	human	JJ
cord-322904-9mta0aem	437	236	glial	glial	JJ
cord-322904-9mta0aem	437	237	cells	cell	NNS
cord-322904-9mta0aem	437	238	by	by	IN
cord-322904-9mta0aem	437	239	clathrindependent	clathrindependent	NN
cord-322904-9mta0aem	437	240	receptor	receptor	NN
cord-322904-9mta0aem	437	241	-	-	HYPH
cord-322904-9mta0aem	437	242	mediated	mediate	VBN
cord-322904-9mta0aem	437	243	endocytosis	endocytosis	NN
cord-322904-9mta0aem	437	244	Carbohydrate	Carbohydrate	NNP
cord-322904-9mta0aem	437	245	dynamics	dynamic	NNS
cord-322904-9mta0aem	437	246	at	at	IN
cord-322904-9mta0aem	437	247	a	a	DT
cord-322904-9mta0aem	437	248	micellar	micellar	JJ
cord-322904-9mta0aem	437	249	surface	surface	NN
cord-322904-9mta0aem	437	250	:	:	:
cord-322904-9mta0aem	438	1	GD1a	GD1a	NNP
cord-322904-9mta0aem	438	2	headgroup	headgroup	NN
cord-322904-9mta0aem	438	3	transformations	transformation	NNS
cord-322904-9mta0aem	438	4	revealed	reveal	VBN
cord-322904-9mta0aem	438	5	by	by	IN
cord-322904-9mta0aem	438	6	NMR	NMR	NNP
cord-322904-9mta0aem	438	7	spectroscopy	spectroscopy	NN
cord-322904-9mta0aem	438	8	A	a	DT
cord-322904-9mta0aem	438	9	JC	JC	NNP
cord-322904-9mta0aem	438	10	virus	virus	NN
cord-322904-9mta0aem	438	11	induced	induce	VBN
cord-322904-9mta0aem	438	12	signal	signal	NN
cord-322904-9mta0aem	438	13	is	be	VBZ
cord-322904-9mta0aem	438	14	required	require	VBN
cord-322904-9mta0aem	438	15	for	for	IN
cord-322904-9mta0aem	438	16	infection	infection	NN
cord-322904-9mta0aem	438	17	of	of	IN
cord-322904-9mta0aem	438	18	glial	glial	JJ
cord-322904-9mta0aem	438	19	cells	cell	NNS
cord-322904-9mta0aem	438	20	by	by	IN
cord-322904-9mta0aem	438	21	a	a	DT
cord-322904-9mta0aem	438	22	clathrin	clathrin	NN
cord-322904-9mta0aem	438	23	and	and	CC
cord-322904-9mta0aem	438	24	eps15	eps15	NN
cord-322904-9mta0aem	438	25	dependent	dependent	JJ
cord-322904-9mta0aem	438	26	pathway	pathway	NN
cord-322904-9mta0aem	438	27	Invasion	Invasion	NNP
cord-322904-9mta0aem	438	28	of	of	IN
cord-322904-9mta0aem	438	29	host	host	NN
cord-322904-9mta0aem	438	30	cells	cell	NNS
cord-322904-9mta0aem	438	31	by	by	IN
cord-322904-9mta0aem	438	32	JC	JC	NNP
cord-322904-9mta0aem	438	33	virus	virus	NN
cord-322904-9mta0aem	439	1	identifies	identify	VBZ
cord-322904-9mta0aem	439	2	a	a	DT
cord-322904-9mta0aem	439	3	novel	novel	JJ
cord-322904-9mta0aem	439	4	role	role	NN
cord-322904-9mta0aem	439	5	for	for	IN
cord-322904-9mta0aem	439	6	caveolae	caveolae	NNP
cord-322904-9mta0aem	439	7	in	in	IN
cord-322904-9mta0aem	439	8	endosomal	endosomal	NNP
cord-322904-9mta0aem	439	9	sorting	sorting	NN
cord-322904-9mta0aem	439	10	of	of	IN
cord-322904-9mta0aem	439	11	noncaveolar	noncaveolar	JJ
cord-322904-9mta0aem	439	12	ligands	ligand	NNS
cord-322904-9mta0aem	439	13	Polyoma	Polyoma	NNP
cord-322904-9mta0aem	439	14	virus	virus	NN
cord-322904-9mta0aem	439	15	capsid	capsid	NN
cord-322904-9mta0aem	439	16	structure	structure	NN
cord-322904-9mta0aem	439	17	at	at	IN
cord-322904-9mta0aem	439	18	22.5	22.5	CD
cord-322904-9mta0aem	439	19	A	a	DT
cord-322904-9mta0aem	439	20	resolution	resolution	NN
cord-322904-9mta0aem	439	21	Avian	avian	JJ
cord-322904-9mta0aem	439	22	and	and	CC
cord-322904-9mta0aem	439	23	human	human	JJ
cord-322904-9mta0aem	439	24	receptor	receptor	NN
cord-322904-9mta0aem	439	25	binding	bind	VBG
cord-322904-9mta0aem	439	26	by	by	IN
cord-322904-9mta0aem	439	27	hemagglutinins	hemagglutinin	NNS
cord-322904-9mta0aem	439	28	of	of	IN
cord-322904-9mta0aem	439	29	influenza	influenza	NN
cord-322904-9mta0aem	439	30	A	a	DT
cord-322904-9mta0aem	439	31	viruses	virus	NNS
cord-322904-9mta0aem	439	32	Binding	bind	VBG
cord-322904-9mta0aem	439	33	of	of	IN
cord-322904-9mta0aem	439	34	influenza	influenza	NN
cord-322904-9mta0aem	439	35	virus	virus	NN
cord-322904-9mta0aem	439	36	hemagglutinin	hemagglutinin	NN
cord-322904-9mta0aem	439	37	to	to	IN
cord-322904-9mta0aem	439	38	analogs	analog	NNS
cord-322904-9mta0aem	439	39	of	of	IN
cord-322904-9mta0aem	439	40	its	-PRON-	PRP$
cord-322904-9mta0aem	439	41	cellsurface	cellsurface	NN
cord-322904-9mta0aem	439	42	receptor	receptor	NN
cord-322904-9mta0aem	439	43	,	,	,
cord-322904-9mta0aem	439	44	sialic	sialic	JJ
cord-322904-9mta0aem	439	45	acid	acid	NN
cord-322904-9mta0aem	439	46	:	:	:
cord-322904-9mta0aem	439	47	analysis	analysis	NN
cord-322904-9mta0aem	439	48	by	by	IN
cord-322904-9mta0aem	439	49	proton	proton	NN
cord-322904-9mta0aem	439	50	nuclear	nuclear	JJ
cord-322904-9mta0aem	439	51	magnetic	magnetic	JJ
cord-322904-9mta0aem	439	52	resonance	resonance	NN
cord-322904-9mta0aem	439	53	spectroscopy	spectroscopy	NN
cord-322904-9mta0aem	439	54	and	and	CC
cord-322904-9mta0aem	439	55	X	x	NN
cord-322904-9mta0aem	439	56	-	-	NN
cord-322904-9mta0aem	439	57	ray	ray	NN
cord-322904-9mta0aem	439	58	crystallography	crystallography	NN
cord-322904-9mta0aem	440	1	Simian	simian	JJ
cord-322904-9mta0aem	440	2	virus	virus	NN
cord-322904-9mta0aem	440	3	40	40	CD
cord-322904-9mta0aem	440	4	depends	depend	VBZ
cord-322904-9mta0aem	440	5	on	on	IN
cord-322904-9mta0aem	440	6	ER	ER	NNP
cord-322904-9mta0aem	440	7	protein	protein	NN
cord-322904-9mta0aem	440	8	folding	folding	NN
cord-322904-9mta0aem	440	9	and	and	CC
cord-322904-9mta0aem	440	10	quality	quality	NN
cord-322904-9mta0aem	440	11	control	control	NN
cord-322904-9mta0aem	440	12	factors	factor	NNS
cord-322904-9mta0aem	440	13	for	for	IN
cord-322904-9mta0aem	440	14	entry	entry	NN
cord-322904-9mta0aem	440	15	into	into	IN
cord-322904-9mta0aem	440	16	host	host	NN
cord-322904-9mta0aem	440	17	cells	cell	NNS
cord-322904-9mta0aem	441	1	Receptor	receptor	NN
cord-322904-9mta0aem	441	2	binding	binding	NN
cord-322904-9mta0aem	441	3	and	and	CC
cord-322904-9mta0aem	441	4	membrane	membrane	NN
cord-322904-9mta0aem	441	5	fusion	fusion	NN
cord-322904-9mta0aem	441	6	in	in	IN
cord-322904-9mta0aem	441	7	virus	virus	NN
cord-322904-9mta0aem	441	8	entry	entry	NN
cord-322904-9mta0aem	441	9	:	:	:
cord-322904-9mta0aem	441	10	the	the	DT
cord-322904-9mta0aem	441	11	influenza	influenza	NN
cord-322904-9mta0aem	441	12	hemagglutinin	hemagglutinin	VBN
cord-322904-9mta0aem	441	13	High	high	JJ
cord-322904-9mta0aem	441	14	-	-	HYPH
cord-322904-9mta0aem	441	15	resolution	resolution	NN
cord-322904-9mta0aem	441	16	structure	structure	NN
cord-322904-9mta0aem	441	17	of	of	IN
cord-322904-9mta0aem	441	18	a	a	DT
cord-322904-9mta0aem	441	19	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	441	20	VP1-oligosaccharide	VP1-oligosaccharide	NNP
cord-322904-9mta0aem	441	21	complex	complex	JJ
cord-322904-9mta0aem	441	22	:	:	:
cord-322904-9mta0aem	441	23	implications	implication	NNS
cord-322904-9mta0aem	441	24	for	for	IN
cord-322904-9mta0aem	441	25	assembly	assembly	NN
cord-322904-9mta0aem	441	26	and	and	CC
cord-322904-9mta0aem	441	27	receptor	receptor	NN
cord-322904-9mta0aem	441	28	binding	bind	VBG
cord-322904-9mta0aem	441	29	Structure	Structure	NNP
cord-322904-9mta0aem	441	30	of	of	IN
cord-322904-9mta0aem	441	31	murine	murine	NNP
cord-322904-9mta0aem	441	32	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	441	33	complexed	complexe	VBN
cord-322904-9mta0aem	441	34	with	with	IN
cord-322904-9mta0aem	441	35	an	an	DT
cord-322904-9mta0aem	441	36	oligosaccharide	oligosaccharide	NN
cord-322904-9mta0aem	441	37	receptor	receptor	NN
cord-322904-9mta0aem	441	38	fragment	fragment	NN
cord-322904-9mta0aem	442	1	The	the	DT
cord-322904-9mta0aem	442	2	structure	structure	NN
cord-322904-9mta0aem	442	3	of	of	IN
cord-322904-9mta0aem	442	4	simian	simian	JJ
cord-322904-9mta0aem	442	5	virus	virus	NN
cord-322904-9mta0aem	442	6	40	40	CD
cord-322904-9mta0aem	442	7	refined	refine	VBN
cord-322904-9mta0aem	442	8	at	at	IN
cord-322904-9mta0aem	442	9	3.1	3.1	CD
cord-322904-9mta0aem	442	10	A	a	DT
cord-322904-9mta0aem	442	11	resolution	resolution	NN
cord-322904-9mta0aem	442	12	Crystal	Crystal	NNP
cord-322904-9mta0aem	442	13	structure	structure	NN
cord-322904-9mta0aem	442	14	of	of	IN
cord-322904-9mta0aem	442	15	botulinum	botulinum	NN
cord-322904-9mta0aem	442	16	neurotoxin	neurotoxin	NN
cord-322904-9mta0aem	442	17	type	type	NN
cord-322904-9mta0aem	442	18	A	a	NN
cord-322904-9mta0aem	442	19	in	in	IN
cord-322904-9mta0aem	442	20	complex	complex	NN
cord-322904-9mta0aem	442	21	with	with	IN
cord-322904-9mta0aem	442	22	the	the	DT
cord-322904-9mta0aem	442	23	cell	cell	NN
cord-322904-9mta0aem	442	24	surface	surface	NN
cord-322904-9mta0aem	442	25	co	co	NN
cord-322904-9mta0aem	442	26	-	-	NN
cord-322904-9mta0aem	442	27	receptor	receptor	JJ
cord-322904-9mta0aem	442	28	GT1b	GT1b	NNP
cord-322904-9mta0aem	442	29	-	-	HYPH
cord-322904-9mta0aem	442	30	insight	insight	NN
cord-322904-9mta0aem	442	31	into	into	IN
cord-322904-9mta0aem	442	32	the	the	DT
cord-322904-9mta0aem	442	33	toxin	toxin	NN
cord-322904-9mta0aem	442	34	-	-	HYPH
cord-322904-9mta0aem	442	35	neuron	neuron	NN
cord-322904-9mta0aem	442	36	interaction	interaction	NN
cord-322904-9mta0aem	442	37	Structure	Structure	NNP
cord-322904-9mta0aem	442	38	of	of	IN
cord-322904-9mta0aem	442	39	the	the	DT
cord-322904-9mta0aem	442	40	uncleaved	uncleaved	JJ
cord-322904-9mta0aem	442	41	human	human	JJ
cord-322904-9mta0aem	442	42	H1	H1	NNP
cord-322904-9mta0aem	442	43	hemagglutinin	hemagglutinin	NN
cord-322904-9mta0aem	442	44	from	from	IN
cord-322904-9mta0aem	442	45	the	the	DT
cord-322904-9mta0aem	442	46	extinct	extinct	JJ
cord-322904-9mta0aem	442	47	1918	1918	CD
cord-322904-9mta0aem	442	48	influenza	influenza	NN
cord-322904-9mta0aem	442	49	virus	virus	NN
cord-322904-9mta0aem	442	50	Structure	structure	NN
cord-322904-9mta0aem	442	51	and	and	CC
cord-322904-9mta0aem	442	52	receptor	receptor	NN
cord-322904-9mta0aem	442	53	specificity	specificity	NN
cord-322904-9mta0aem	442	54	of	of	IN
cord-322904-9mta0aem	442	55	the	the	DT
cord-322904-9mta0aem	442	56	hemagglutinin	hemagglutinin	NN
cord-322904-9mta0aem	442	57	from	from	IN
cord-322904-9mta0aem	442	58	an	an	DT
cord-322904-9mta0aem	442	59	H5N1	H5N1	NNP
cord-322904-9mta0aem	442	60	influenza	influenza	NN
cord-322904-9mta0aem	442	61	virus	virus	NN
cord-322904-9mta0aem	442	62	Neoplasms	Neoplasms	NNP
cord-322904-9mta0aem	442	63	in	in	IN
cord-322904-9mta0aem	442	64	mice	mouse	NNS
cord-322904-9mta0aem	442	65	inoculated	inoculate	VBN
cord-322904-9mta0aem	442	66	with	with	IN
cord-322904-9mta0aem	442	67	a	a	DT
cord-322904-9mta0aem	442	68	tumor	tumor	NN
cord-322904-9mta0aem	442	69	agent	agent	NN
cord-322904-9mta0aem	442	70	carried	carry	VBN
cord-322904-9mta0aem	442	71	in	in	IN
cord-322904-9mta0aem	442	72	tissue	tissue	NN
cord-322904-9mta0aem	442	73	culture	culture	NN
cord-322904-9mta0aem	443	1	The	the	DT
cord-322904-9mta0aem	443	2	vacuolating	vacuolating	NN
cord-322904-9mta0aem	443	3	virus	virus	NN
cord-322904-9mta0aem	443	4	,	,	,
cord-322904-9mta0aem	443	5	S.V.	S.V.	NNP
cord-322904-9mta0aem	443	6	40	40	CD
cord-322904-9mta0aem	443	7	Cell	cell	NN
cord-322904-9mta0aem	443	8	type	type	NN
cord-322904-9mta0aem	443	9	-	-	HYPH
cord-322904-9mta0aem	443	10	specific	specific	JJ
cord-322904-9mta0aem	443	11	expression	expression	NN
cord-322904-9mta0aem	443	12	of	of	IN
cord-322904-9mta0aem	443	13	JC	JC	NNP
cord-322904-9mta0aem	443	14	virus	virus	NN
cord-322904-9mta0aem	443	15	early	early	JJ
cord-322904-9mta0aem	443	16	promoter	promoter	NN
cord-322904-9mta0aem	443	17	is	be	VBZ
cord-322904-9mta0aem	443	18	determined	determine	VBN
cord-322904-9mta0aem	443	19	by	by	IN
cord-322904-9mta0aem	443	20	positive	positive	JJ
cord-322904-9mta0aem	443	21	and	and	CC
cord-322904-9mta0aem	443	22	negative	negative	JJ
cord-322904-9mta0aem	443	23	regulation	regulation	NN
cord-322904-9mta0aem	443	24	Gangliosides	ganglioside	NNS
cord-322904-9mta0aem	443	25	are	be	VBP
cord-322904-9mta0aem	443	26	receptors	receptor	NNS
cord-322904-9mta0aem	443	27	for	for	IN
cord-322904-9mta0aem	443	28	murine	murine	JJ
cord-322904-9mta0aem	443	29	polyomavirus	polyomavirus	NNP
cord-322904-9mta0aem	443	30	and	and	CC
cord-322904-9mta0aem	444	1	SV40	SV40	NNP
cord-322904-9mta0aem	445	1	The	the	DT
cord-322904-9mta0aem	445	2	three	three	CD
cord-322904-9mta0aem	445	3	-	-	HYPH
cord-322904-9mta0aem	445	4	dimensional	dimensional	JJ
cord-322904-9mta0aem	445	5	structure	structure	NN
cord-322904-9mta0aem	445	6	of	of	IN
cord-322904-9mta0aem	445	7	canine	canine	JJ
cord-322904-9mta0aem	445	8	parvovirus	parvovirus	NN
cord-322904-9mta0aem	445	9	and	and	CC
cord-322904-9mta0aem	445	10	its	-PRON-	PRP$
cord-322904-9mta0aem	445	11	functional	functional	JJ
cord-322904-9mta0aem	445	12	implications	implication	NNS
cord-322904-9mta0aem	445	13	Human	human	JJ
cord-322904-9mta0aem	445	14	and	and	CC
cord-322904-9mta0aem	445	15	avian	avian	JJ
cord-322904-9mta0aem	445	16	influenza	influenza	NN
cord-322904-9mta0aem	445	17	viruses	virus	NNS
cord-322904-9mta0aem	445	18	target	target	VBP
cord-322904-9mta0aem	445	19	different	different	JJ
cord-322904-9mta0aem	445	20	cells	cell	NNS
cord-322904-9mta0aem	445	21	in	in	IN
cord-322904-9mta0aem	445	22	the	the	DT
cord-322904-9mta0aem	445	23	lower	low	JJR
cord-322904-9mta0aem	445	24	respiratory	respiratory	JJ
cord-322904-9mta0aem	445	25	tract	tract	NN
cord-322904-9mta0aem	445	26	of	of	IN
cord-322904-9mta0aem	445	27	humans	human	NNS
cord-322904-9mta0aem	445	28	and	and	CC
cord-322904-9mta0aem	445	29	other	other	JJ
cord-322904-9mta0aem	445	30	mammals	mammal	NNS
cord-322904-9mta0aem	445	31	Sialic	Sialic	NNP
cord-322904-9mta0aem	445	32	acids	acid	NNS
cord-322904-9mta0aem	445	33	in	in	IN
cord-322904-9mta0aem	445	34	human	human	JJ
cord-322904-9mta0aem	445	35	health	health	NN
cord-322904-9mta0aem	445	36	and	and	CC
cord-322904-9mta0aem	445	37	disease	disease	NNP
cord-322904-9mta0aem	445	38	Structure	Structure	NNP
cord-322904-9mta0aem	445	39	of	of	IN
cord-322904-9mta0aem	445	40	the	the	DT
cord-322904-9mta0aem	445	41	influenza	influenza	NN
cord-322904-9mta0aem	445	42	virus	virus	NN
cord-322904-9mta0aem	445	43	haemagglutinin	haemagglutinin	NNP
cord-322904-9mta0aem	445	44	complexed	complexe	VBN
cord-322904-9mta0aem	445	45	with	with	IN
cord-322904-9mta0aem	445	46	its	-PRON-	PRP$
cord-322904-9mta0aem	445	47	receptor	receptor	NN
cord-322904-9mta0aem	445	48	,	,	,
cord-322904-9mta0aem	445	49	sialic	sialic	JJ
cord-322904-9mta0aem	445	50	acid	acid	NN
cord-322904-9mta0aem	445	51	Role	role	NN
cord-322904-9mta0aem	445	52	of	of	IN
cord-322904-9mta0aem	445	53	nuclear	nuclear	JJ
cord-322904-9mta0aem	445	54	pore	pore	NN
cord-322904-9mta0aem	445	55	complex	complex	NN
cord-322904-9mta0aem	445	56	in	in	IN
cord-322904-9mta0aem	445	57	simian	simian	JJ
cord-322904-9mta0aem	445	58	virus	virus	NN
cord-322904-9mta0aem	445	59	40	40	CD
cord-322904-9mta0aem	445	60	nuclear	nuclear	NN
cord-322904-9mta0aem	445	61	targeting	target	VBG
cord-322904-9mta0aem	445	62	Seeing	see	VBG
cord-322904-9mta0aem	445	63	the	the	DT
cord-322904-9mta0aem	445	64	herpesvirus	herpesvirus	NN
cord-322904-9mta0aem	445	65	capsid	capsid	NN
cord-322904-9mta0aem	445	66	at	at	IN
cord-322904-9mta0aem	445	67	8.5	8.5	CD
cord-322904-9mta0aem	445	68	A	a	DT
cord-322904-9mta0aem	446	1	We	-PRON-	PRP
cord-322904-9mta0aem	446	2	would	would	MD
cord-322904-9mta0aem	446	3	like	like	VB
cord-322904-9mta0aem	446	4	to	to	TO
cord-322904-9mta0aem	446	5	thank	thank	VB
cord-322904-9mta0aem	446	6	Wendy	Wendy	NNP
cord-322904-9mta0aem	446	7	Virgadamo	Virgadamo	NNP
cord-322904-9mta0aem	446	8	for	for	IN
cord-322904-9mta0aem	446	9	designing	design	VBG
cord-322904-9mta0aem	446	10	Figs	Figs	NNP
cord-322904-9mta0aem	446	11	.	.	.
cord-322904-9mta0aem	447	1	1	1	LS
cord-322904-9mta0aem	447	2	-	-	SYM
cord-322904-9mta0aem	447	3	3	3	CD
cord-322904-9mta0aem	447	4	.	.	.
cord-322904-9mta0aem	448	1	Work	work	VB
cord-322904-9mta0aem	448	2	in	in	IN
cord-322904-9mta0aem	448	3	the	the	DT
cord-322904-9mta0aem	448	4	Atwood	Atwood	NNP
cord-322904-9mta0aem	448	5	lab	lab	NN
cord-322904-9mta0aem	448	6	is	be	VBZ
cord-322904-9mta0aem	448	7	supported	support	VBN
cord-322904-9mta0aem	448	8	by	by	IN
cord-322904-9mta0aem	448	9	NIH	NIH	NNP
cord-322904-9mta0aem	448	10	grants	grant	NNS
cord-322904-9mta0aem	448	11	CA71878	CA71878	NNP
cord-322904-9mta0aem	448	12	and	and	CC
cord-322904-9mta0aem	448	13	NS43097	ns43097	NN
cord-322904-9mta0aem	448	14	.	.	.
cord-322904-9mta0aem	449	1	Work	work	VB
cord-322904-9mta0aem	449	2	in	in	IN
cord-322904-9mta0aem	449	3	the	the	DT
cord-322904-9mta0aem	449	4	Stehle	Stehle	NNP
cord-322904-9mta0aem	449	5	lab	lab	NN
cord-322904-9mta0aem	449	6	was	be	VBD
cord-322904-9mta0aem	449	7	supported	support	VBN
cord-322904-9mta0aem	449	8	by	by	IN
cord-322904-9mta0aem	449	9	the	the	DT
cord-322904-9mta0aem	449	10	Deutsche	Deutsche	NNP
cord-322904-9mta0aem	449	11	Forschungsgemeinschaft	Forschungsgemeinschaft	NNP
cord-322904-9mta0aem	449	12	(	(	-LRB-
cord-322904-9mta0aem	449	13	SFB-685	SFB-685	NNP
cord-322904-9mta0aem	449	14	)	)	-RRB-
cord-322904-9mta0aem	449	15	.	.	.