id author title date pages extension mime words sentences flesch summary cache txt cord-012091-3bo88tux Ibrahim, Madiha Salah Host-specific genetic variation of highly pathogenic avian influenza viruses (H5N1) 2011-02-17 .txt text/plain 2486 132 52 The complete genome sequences of two isolates A/chicken/Egypt/CL6/07 (CL6/07) and A/duck/Egypt/D2br10/07 (D2br10/07) of highly pathogenic avian influenza virus (HPAI) H5N1 isolated at the beginning of 2007 outbreak in Egypt were determined and compared with all Egyptian HPAI H5N1 sequences available in the GenBank. For 2007 and 2008, the CL6/07 and D2br10/07-specific amino acids were detected in GenBank available sequences but they could not be species-correlated due to the low number of duck reference sequences, except the Lys140 (H5 Table 1 ). In our analysis, comparative genetic characterization of the eight RNA segments of CL6/07 and D2br10/07 together with 2006-2010 GenBank Egyptian reference sequences showed that both viruses had nucleotide as well as amino acid differences that appeared to be specific for each, except for the M gene that was highly conserved. Highly pathogenic avian influenza virus subtype H5N1 in Africa: a comprehensive phylogenetic analysis and molecular characterization of isolates ./cache/cord-012091-3bo88tux.txt ./txt/cord-012091-3bo88tux.txt