id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269340-o9jdt86j	Callison, Scott Andrew	Infectious Bronchitis Virus S2 Gene Sequence Variability May Affect S1 Subunit Specific Antibody Binding	1999		.txt	text/plain	2116	110	60	The S2 gene of several strains of infectious bronchitis virus (IBV) belonging to the Arkansas, Connecticut, and Florida serotypes was sequenced. Thus, we are interested in examining the S2 gene and its deduced amino acid sequence of IBV strains in an attempt to determine if it plays a role in the binding of S1 subunit speci®c antibodies to the virus. We also selected Connecticut 46 and Florida 18288 for S2 gene sequencing because these strains are known to share 96.6% deduced amino acid identity for their S1 subunits, yet remain serologically distinct (14, 15) . In the alignment, members of the U.S. serotypes Arkansas, Mass, Connecticut, Florida, and foreign S2 Gene Sequence Variability serogroups B and C, fall into the same groupings as observed when deduced amino acid sequence data for the S1 subunit is used for phylogenetic analysis (Fig. 3) . One change in the GAV 92 S2 deduced amino acid sequence ( position 50 E?G) led to a 180 ¯i p in the secondary structure prediction of the S2 subunit.	./cache/cord-269340-o9jdt86j.txt	./txt/cord-269340-o9jdt86j.txt