id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-260422-z22t57ju	Godet, Julien	Comparative nucleic acid chaperone properties of the nucleocapsid protein NCp7 and Tat protein of HIV-1	2012-06-26		.txt	text/plain	9180	486	49	Today's view is that RNA chaperones are nucleic acid binding proteins present in all living organisms, including viruses, where they Abbreviations: HIV-1, human immunodeficiency virus-type I; NCp7, nucleocapsid protein of HIV-1; ZF, zinc finger; NA, nucleic acid; TAR, transactivation response element; PBS, primer binding site; AA, amino acids. The substantial nucleic acid chaperone properties exhibited by Tat may account for its ability to promote the annealing of the primer tRNA to the viral RNA (Kameoka et al., 2002) and intervene in the first strand transfer (Boudier et al., 2010) and by this way, to stimulate RTion as does NCp7 (Harrich et al., 1997; Ulich et al., 1999; Apolloni et al., 2007) . Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minusstrand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site	./cache/cord-260422-z22t57ju.txt	./txt/cord-260422-z22t57ju.txt