id author title date pages extension mime words sentences flesch summary cache txt cord-338602-6n309bnp Gadotti, Ana Carolina IFN-γ is an independent risk factor associated with mortality in patients with moderate and severe COVID-19 infection 2020-09-23 .txt text/plain 2888 183 53 title: IFN-γ is an independent risk factor associated with mortality in patients with moderate and severe COVID-19 infection We proposed a study in patients with moderate to severe COVID-19 infection to evaluate the interleukin patterns and its role as prognosis factors. A reasonable hypothesis is that (i) pro-inflammatory innate immunity and (ii) anti-inflammatory system are related to disease severity or death once IL-6, IL-8, and IL10 are closely described as prognostic factors in patients diagnosed with COVID-19 1, 3, 7 . Previous studies have not reported the association between IFN-γ and death, even evaluating the COVID-19-reactive CD69+ expressing IFN-γ producing CD8+ T in 25 patients with severe and moderate disease 22 . Suppressed T cell-mediated immunity in patients with COVID-19: A clinical retrospective study in Wuhan Levels of cytokines from patients with moderate and severe COVID-19 infection according to the outcome (data in the median with IQR) ./cache/cord-338602-6n309bnp.txt ./txt/cord-338602-6n309bnp.txt