id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-346264-hnwgzt6v	Nagai, Makoto	Porcine sapoviruses: Pathogenesis, epidemiology, genetic diversity, and diagnosis	2020-05-26		.txt	text/plain	2005	108	60	Although GIII Cowden strain replicated in the villous epithelial cells and caused intestinal lesions in the proximal small intestines (mainly in duodenal and less in jejunum), leading to mild to severe diarrhea, in the orally inoculated neonatal gnotobiotic pigs, the significance of porcine SaVs in different ages of pigs with diarrhea in the field is still undetermined. The first porcine sapovirus (SaV), the Cowden strain was discovered by electron microscopy in the intestinal contents of a 27-day-old diarrheic nursing pig in the United State in 1980 (Saif et al., 1980 . In this review, we will summarize current knowledge on the pathogenesis of GIII Cowden strain, the epidemiology and genetic diversity of porcine SaVs, and the diagnosis of SaV infection in pigs. It may also explain why porcine SaV Cowden strain did not replicate in other organs when piglets were inoculated intravenously (IV) with the virus (Guo et al., 2001) .	./cache/cord-346264-hnwgzt6v.txt	./txt/cord-346264-hnwgzt6v.txt