id	sid	tid	token	lemma	pos
cord-285180-32bxx94u	1	1	key	key	JJ
cord-285180-32bxx94u	1	2	:	:	:
cord-285180-32bxx94u	1	3	cord-285180	cord-285180	VB
cord-285180-32bxx94u	1	4	-	-	HYPH
cord-285180-32bxx94u	1	5	32bxx94u	32bxx94u	JJ
cord-285180-32bxx94u	1	6	authors	author	NNS
cord-285180-32bxx94u	1	7	:	:	:
cord-285180-32bxx94u	1	8	Lee	Lee	NNP
cord-285180-32bxx94u	1	9	,	,	,
cord-285180-32bxx94u	1	10	Sunhee	Sunhee	NNP
cord-285180-32bxx94u	1	11	;	;	:
cord-285180-32bxx94u	1	12	Lee	Lee	NNP
cord-285180-32bxx94u	1	13	,	,	,
cord-285180-32bxx94u	1	14	Changhee	Changhee	NNP
cord-285180-32bxx94u	1	15	title	title	NN
cord-285180-32bxx94u	1	16	:	:	:
cord-285180-32bxx94u	1	17	Functional	functional	JJ
cord-285180-32bxx94u	1	18	characterization	characterization	NN
cord-285180-32bxx94u	1	19	and	and	CC
cord-285180-32bxx94u	1	20	proteomic	proteomic	JJ
cord-285180-32bxx94u	1	21	analysis	analysis	NN
cord-285180-32bxx94u	1	22	of	of	IN
cord-285180-32bxx94u	1	23	the	the	DT
cord-285180-32bxx94u	1	24	nucleocapsid	nucleocapsid	NNP
cord-285180-32bxx94u	1	25	protein	protein	NN
cord-285180-32bxx94u	1	26	of	of	IN
cord-285180-32bxx94u	1	27	porcine	porcine	JJ
cord-285180-32bxx94u	1	28	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	1	29	date	date	NN
cord-285180-32bxx94u	1	30	:	:	:
cord-285180-32bxx94u	1	31	2015	2015	CD
cord-285180-32bxx94u	1	32	-	-	SYM
cord-285180-32bxx94u	1	33	10	10	CD
cord-285180-32bxx94u	1	34	-	-	SYM
cord-285180-32bxx94u	1	35	02	02	CD
cord-285180-32bxx94u	1	36	journal	journal	NN
cord-285180-32bxx94u	1	37	:	:	:
cord-285180-32bxx94u	2	1	Virus	virus	NN
cord-285180-32bxx94u	2	2	Res	res	NN
cord-285180-32bxx94u	2	3	DOI	doi	NN
cord-285180-32bxx94u	3	1	:	:	:
cord-285180-32bxx94u	3	2	10.1016	10.1016	CD
cord-285180-32bxx94u	3	3	/	/	SYM
cord-285180-32bxx94u	3	4	j.virusres.2015.06.013	j.virusres.2015.06.013	CD
cord-285180-32bxx94u	3	5	sha	sha	NNP
cord-285180-32bxx94u	3	6	:	:	:
cord-285180-32bxx94u	4	1	7ade2824ccb1bdf7839a51ca3622c291e5663ac6	7ade2824ccb1bdf7839a51ca3622c291e5663ac6	NNP
cord-285180-32bxx94u	4	2	doc_id	doc_id	CD
cord-285180-32bxx94u	5	1	:	:	:
cord-285180-32bxx94u	5	2	285180	285180	CD
cord-285180-32bxx94u	5	3	cord_uid	cord_uid	NNS
cord-285180-32bxx94u	5	4	:	:	:
cord-285180-32bxx94u	6	1	32bxx94u	32bxx94u	CD
cord-285180-32bxx94u	6	2	Porcine	Porcine	NNP
cord-285180-32bxx94u	6	3	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	6	4	(	(	-LRB-
cord-285180-32bxx94u	6	5	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	6	6	)	)	-RRB-
cord-285180-32bxx94u	6	7	is	be	VBZ
cord-285180-32bxx94u	6	8	a	a	DT
cord-285180-32bxx94u	6	9	newly	newly	RB
cord-285180-32bxx94u	6	10	discovered	discover	VBN
cord-285180-32bxx94u	6	11	enterotropic	enterotropic	NNP
cord-285180-32bxx94u	6	12	swine	swine	NN
cord-285180-32bxx94u	6	13	coronavirus	coronavirus	NN
cord-285180-32bxx94u	6	14	that	that	WDT
cord-285180-32bxx94u	6	15	causes	cause	VBZ
cord-285180-32bxx94u	6	16	enteritis	enteritis	NN
cord-285180-32bxx94u	6	17	and	and	CC
cord-285180-32bxx94u	6	18	diarrhea	diarrhea	NN
cord-285180-32bxx94u	6	19	in	in	IN
cord-285180-32bxx94u	6	20	piglets	piglet	NNS
cord-285180-32bxx94u	6	21	.	.	.
cord-285180-32bxx94u	7	1	Like	like	IN
cord-285180-32bxx94u	7	2	other	other	JJ
cord-285180-32bxx94u	7	3	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	7	4	,	,	,
cord-285180-32bxx94u	7	5	PDCoV	pdcov	ADD
cord-285180-32bxx94u	7	6	commonly	commonly	RB
cord-285180-32bxx94u	7	7	contains	contain	VBZ
cord-285180-32bxx94u	7	8	4	4	CD
cord-285180-32bxx94u	7	9	major	major	JJ
cord-285180-32bxx94u	7	10	structural	structural	JJ
cord-285180-32bxx94u	7	11	proteins	protein	NNS
cord-285180-32bxx94u	7	12	:	:	:
cord-285180-32bxx94u	7	13	spike	spike	NN
cord-285180-32bxx94u	7	14	(	(	-LRB-
cord-285180-32bxx94u	7	15	S	S	NNP
cord-285180-32bxx94u	7	16	)	)	-RRB-
cord-285180-32bxx94u	7	17	,	,	,
cord-285180-32bxx94u	7	18	envelope	envelope	NN
cord-285180-32bxx94u	7	19	(	(	-LRB-
cord-285180-32bxx94u	7	20	E	E	NNP
cord-285180-32bxx94u	7	21	)	)	-RRB-
cord-285180-32bxx94u	7	22	,	,	,
cord-285180-32bxx94u	7	23	membrane	membrane	NN
cord-285180-32bxx94u	7	24	(	(	-LRB-
cord-285180-32bxx94u	7	25	M	M	NNP
cord-285180-32bxx94u	7	26	)	)	-RRB-
cord-285180-32bxx94u	7	27	,	,	,
cord-285180-32bxx94u	7	28	and	and	CC
cord-285180-32bxx94u	7	29	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	7	30	(	(	-LRB-
cord-285180-32bxx94u	7	31	N	N	NNP
cord-285180-32bxx94u	7	32	)	)	-RRB-
cord-285180-32bxx94u	7	33	proteins	protein	NNS
cord-285180-32bxx94u	7	34	.	.	.
cord-285180-32bxx94u	8	1	Among	among	IN
cord-285180-32bxx94u	8	2	these	these	DT
cord-285180-32bxx94u	8	3	,	,	,
cord-285180-32bxx94u	8	4	the	the	DT
cord-285180-32bxx94u	8	5	N	N	NNP
cord-285180-32bxx94u	8	6	protein	protein	NN
cord-285180-32bxx94u	8	7	is	be	VBZ
cord-285180-32bxx94u	8	8	known	know	VBN
cord-285180-32bxx94u	8	9	to	to	TO
cord-285180-32bxx94u	8	10	be	be	VB
cord-285180-32bxx94u	8	11	the	the	DT
cord-285180-32bxx94u	8	12	most	most	RBS
cord-285180-32bxx94u	8	13	abundant	abundant	JJ
cord-285180-32bxx94u	8	14	and	and	CC
cord-285180-32bxx94u	8	15	multifunctional	multifunctional	JJ
cord-285180-32bxx94u	8	16	viral	viral	JJ
cord-285180-32bxx94u	8	17	component	component	NN
cord-285180-32bxx94u	8	18	.	.	.
cord-285180-32bxx94u	9	1	Therefore	therefore	RB
cord-285180-32bxx94u	9	2	,	,	,
cord-285180-32bxx94u	9	3	as	as	IN
cord-285180-32bxx94u	9	4	the	the	DT
cord-285180-32bxx94u	9	5	first	first	JJ
cord-285180-32bxx94u	9	6	step	step	NN
cord-285180-32bxx94u	9	7	toward	toward	IN
cord-285180-32bxx94u	9	8	understanding	understand	VBG
cord-285180-32bxx94u	9	9	the	the	DT
cord-285180-32bxx94u	9	10	biology	biology	NN
cord-285180-32bxx94u	9	11	of	of	IN
cord-285180-32bxx94u	9	12	PDCoV	pdcov	NN
cord-285180-32bxx94u	9	13	,	,	,
cord-285180-32bxx94u	9	14	the	the	DT
cord-285180-32bxx94u	9	15	present	present	JJ
cord-285180-32bxx94u	9	16	study	study	NN
cord-285180-32bxx94u	9	17	investigated	investigate	VBD
cord-285180-32bxx94u	9	18	functional	functional	JJ
cord-285180-32bxx94u	9	19	characteristics	characteristic	NNS
cord-285180-32bxx94u	9	20	and	and	CC
cord-285180-32bxx94u	9	21	expression	expression	NN
cord-285180-32bxx94u	9	22	dynamics	dynamic	NNS
cord-285180-32bxx94u	9	23	of	of	IN
cord-285180-32bxx94u	9	24	host	host	NN
cord-285180-32bxx94u	9	25	proteins	protein	NNS
cord-285180-32bxx94u	9	26	in	in	IN
cord-285180-32bxx94u	9	27	a	a	DT
cord-285180-32bxx94u	9	28	stable	stable	JJ
cord-285180-32bxx94u	9	29	porcine	porcine	JJ
cord-285180-32bxx94u	9	30	cell	cell	NN
cord-285180-32bxx94u	9	31	line	line	NN
cord-285180-32bxx94u	9	32	constitutively	constitutively	RB
cord-285180-32bxx94u	9	33	expressing	express	VBG
cord-285180-32bxx94u	9	34	the	the	DT
cord-285180-32bxx94u	9	35	PDCoV	pdcov	NN
cord-285180-32bxx94u	9	36	N	n	CD
cord-285180-32bxx94u	9	37	protein	protein	NN
cord-285180-32bxx94u	9	38	.	.	.
cord-285180-32bxx94u	10	1	Similar	similar	JJ
cord-285180-32bxx94u	10	2	to	to	IN
cord-285180-32bxx94u	10	3	N	n	CD
cord-285180-32bxx94u	10	4	proteins	protein	NNS
cord-285180-32bxx94u	10	5	of	of	IN
cord-285180-32bxx94u	10	6	other	other	JJ
cord-285180-32bxx94u	10	7	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	10	8	,	,	,
cord-285180-32bxx94u	10	9	the	the	DT
cord-285180-32bxx94u	10	10	PDCoV	pdcov	NN
cord-285180-32bxx94u	10	11	N	N	NNP
cord-285180-32bxx94u	10	12	protein	protein	NN
cord-285180-32bxx94u	10	13	was	be	VBD
cord-285180-32bxx94u	10	14	found	find	VBN
cord-285180-32bxx94u	10	15	to	to	TO
cord-285180-32bxx94u	10	16	interact	interact	VB
cord-285180-32bxx94u	10	17	with	with	IN
cord-285180-32bxx94u	10	18	itself	-PRON-	PRP
cord-285180-32bxx94u	10	19	to	to	TO
cord-285180-32bxx94u	10	20	form	form	VB
cord-285180-32bxx94u	10	21	non	non	JJ
cord-285180-32bxx94u	10	22	-	-	JJ
cord-285180-32bxx94u	10	23	covalently	covalently	RB
cord-285180-32bxx94u	10	24	linked	link	VBN
cord-285180-32bxx94u	10	25	oligomers	oligomer	NNS
cord-285180-32bxx94u	10	26	and	and	CC
cord-285180-32bxx94u	10	27	was	be	VBD
cord-285180-32bxx94u	10	28	mainly	mainly	RB
cord-285180-32bxx94u	10	29	localized	localize	VBN
cord-285180-32bxx94u	10	30	to	to	IN
cord-285180-32bxx94u	10	31	the	the	DT
cord-285180-32bxx94u	10	32	nucleolus	nucleolus	NN
cord-285180-32bxx94u	10	33	.	.	.
cord-285180-32bxx94u	11	1	We	-PRON-	PRP
cord-285180-32bxx94u	11	2	then	then	RB
cord-285180-32bxx94u	11	3	assessed	assess	VBD
cord-285180-32bxx94u	11	4	alterations	alteration	NNS
cord-285180-32bxx94u	11	5	in	in	IN
cord-285180-32bxx94u	11	6	production	production	NN
cord-285180-32bxx94u	11	7	levels	level	NNS
cord-285180-32bxx94u	11	8	of	of	IN
cord-285180-32bxx94u	11	9	proteins	protein	NNS
cord-285180-32bxx94u	11	10	in	in	IN
cord-285180-32bxx94u	11	11	the	the	DT
cord-285180-32bxx94u	11	12	N	N	NNP
cord-285180-32bxx94u	11	13	-	-	HYPH
cord-285180-32bxx94u	11	14	expressing	express	VBG
cord-285180-32bxx94u	11	15	PK	PK	NNP
cord-285180-32bxx94u	11	16	(	(	-LRB-
cord-285180-32bxx94u	11	17	PK	PK	NNP
cord-285180-32bxx94u	11	18	-	-	HYPH
cord-285180-32bxx94u	11	19	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	11	20	-	-	HYPH
cord-285180-32bxx94u	11	21	N	n	NN
cord-285180-32bxx94u	11	22	)	)	-RRB-
cord-285180-32bxx94u	11	23	cells	cell	NNS
cord-285180-32bxx94u	11	24	at	at	IN
cord-285180-32bxx94u	11	25	different	different	JJ
cord-285180-32bxx94u	11	26	time	time	NN
cord-285180-32bxx94u	11	27	points	point	NNS
cord-285180-32bxx94u	11	28	by	by	IN
cord-285180-32bxx94u	11	29	means	mean	NNS
cord-285180-32bxx94u	11	30	of	of	IN
cord-285180-32bxx94u	11	31	proteomic	proteomic	JJ
cord-285180-32bxx94u	11	32	analysis	analysis	NN
cord-285180-32bxx94u	11	33	.	.	.
cord-285180-32bxx94u	12	1	According	accord	VBG
cord-285180-32bxx94u	12	2	to	to	IN
cord-285180-32bxx94u	12	3	the	the	DT
cord-285180-32bxx94u	12	4	results	result	NNS
cord-285180-32bxx94u	12	5	of	of	IN
cord-285180-32bxx94u	12	6	high	high	JJ
cord-285180-32bxx94u	12	7	-	-	HYPH
cord-285180-32bxx94u	12	8	resolution	resolution	NN
cord-285180-32bxx94u	12	9	two	two	CD
cord-285180-32bxx94u	12	10	-	-	HYPH
cord-285180-32bxx94u	12	11	dimensional	dimensional	JJ
cord-285180-32bxx94u	12	12	gel	gel	NN
cord-285180-32bxx94u	12	13	electrophoresis	electrophoresis	NN
cord-285180-32bxx94u	12	14	,	,	,
cord-285180-32bxx94u	12	15	a	a	DT
cord-285180-32bxx94u	12	16	total	total	NN
cord-285180-32bxx94u	12	17	of	of	IN
cord-285180-32bxx94u	12	18	43	43	CD
cord-285180-32bxx94u	12	19	protein	protein	NN
cord-285180-32bxx94u	12	20	spots	spot	NNS
cord-285180-32bxx94u	12	21	were	be	VBD
cord-285180-32bxx94u	12	22	initially	initially	RB
cord-285180-32bxx94u	12	23	found	find	VBN
cord-285180-32bxx94u	12	24	to	to	TO
cord-285180-32bxx94u	12	25	be	be	VB
cord-285180-32bxx94u	12	26	differentially	differentially	RB
cord-285180-32bxx94u	12	27	expressed	express	VBN
cord-285180-32bxx94u	12	28	in	in	IN
cord-285180-32bxx94u	12	29	PK	PK	NNP
cord-285180-32bxx94u	12	30	-	-	HYPH
cord-285180-32bxx94u	12	31	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	12	32	-	-	HYPH
cord-285180-32bxx94u	12	33	N	n	CD
cord-285180-32bxx94u	12	34	cells	cell	NNS
cord-285180-32bxx94u	12	35	in	in	IN
cord-285180-32bxx94u	12	36	comparison	comparison	NN
cord-285180-32bxx94u	12	37	with	with	IN
cord-285180-32bxx94u	12	38	control	control	NN
cord-285180-32bxx94u	12	39	PK	PK	NNP
cord-285180-32bxx94u	12	40	cells	cell	NNS
cord-285180-32bxx94u	12	41	.	.	.
cord-285180-32bxx94u	13	1	Of	of	IN
cord-285180-32bxx94u	13	2	these	these	DT
cord-285180-32bxx94u	13	3	spots	spot	NNS
cord-285180-32bxx94u	13	4	,	,	,
cord-285180-32bxx94u	13	5	10	10	CD
cord-285180-32bxx94u	13	6	protein	protein	NN
cord-285180-32bxx94u	13	7	spots	spot	NNS
cord-285180-32bxx94u	13	8	showed	show	VBD
cord-285180-32bxx94u	13	9	a	a	DT
cord-285180-32bxx94u	13	10	statistically	statistically	RB
cord-285180-32bxx94u	13	11	significant	significant	JJ
cord-285180-32bxx94u	13	12	alteration	alteration	NN
cord-285180-32bxx94u	13	13	,	,	,
cord-285180-32bxx94u	13	14	including	include	VBG
cord-285180-32bxx94u	13	15	8	8	CD
cord-285180-32bxx94u	13	16	up	up	RB
cord-285180-32bxx94u	13	17	-	-	HYPH
cord-285180-32bxx94u	13	18	regulated	regulate	VBN
cord-285180-32bxx94u	13	19	and	and	CC
cord-285180-32bxx94u	13	20	2	2	CD
cord-285180-32bxx94u	13	21	down	down	RB
cord-285180-32bxx94u	13	22	-	-	HYPH
cord-285180-32bxx94u	13	23	regulated	regulate	VBN
cord-285180-32bxx94u	13	24	protein	protein	NN
cord-285180-32bxx94u	13	25	spots	spot	NNS
cord-285180-32bxx94u	13	26	and	and	CC
cord-285180-32bxx94u	13	27	were	be	VBD
cord-285180-32bxx94u	13	28	picked	pick	VBN
cord-285180-32bxx94u	13	29	for	for	IN
cord-285180-32bxx94u	13	30	subsequent	subsequent	JJ
cord-285180-32bxx94u	13	31	protein	protein	NN
cord-285180-32bxx94u	13	32	identification	identification	NN
cord-285180-32bxx94u	13	33	by	by	IN
cord-285180-32bxx94u	13	34	peptide	peptide	JJ
cord-285180-32bxx94u	13	35	mass	mass	NN
cord-285180-32bxx94u	13	36	fingerprinting	fingerprinting	NN
cord-285180-32bxx94u	13	37	following	follow	VBG
cord-285180-32bxx94u	13	38	matrix	matrix	NN
cord-285180-32bxx94u	13	39	-	-	HYPH
cord-285180-32bxx94u	13	40	assisted	assist	VBN
cord-285180-32bxx94u	13	41	laser	laser	NN
cord-285180-32bxx94u	13	42	desorption	desorption	NN
cord-285180-32bxx94u	13	43	/	/	SYM
cord-285180-32bxx94u	13	44	ionization	ionization	NN
cord-285180-32bxx94u	13	45	time	time	NN
cord-285180-32bxx94u	13	46	-	-	HYPH
cord-285180-32bxx94u	13	47	of	of	IN
cord-285180-32bxx94u	13	48	-	-	HYPH
cord-285180-32bxx94u	13	49	flight	flight	NN
cord-285180-32bxx94u	13	50	mass	mass	NN
cord-285180-32bxx94u	13	51	spectrometry	spectrometry	NN
cord-285180-32bxx94u	13	52	.	.	.
cord-285180-32bxx94u	14	1	The	the	DT
cord-285180-32bxx94u	14	2	affected	affected	JJ
cord-285180-32bxx94u	14	3	cellular	cellular	JJ
cord-285180-32bxx94u	14	4	proteins	protein	NNS
cord-285180-32bxx94u	14	5	that	that	WDT
cord-285180-32bxx94u	14	6	we	-PRON-	PRP
cord-285180-32bxx94u	14	7	identified	identify	VBD
cord-285180-32bxx94u	14	8	in	in	IN
cord-285180-32bxx94u	14	9	this	this	DT
cord-285180-32bxx94u	14	10	study	study	NN
cord-285180-32bxx94u	14	11	were	be	VBD
cord-285180-32bxx94u	14	12	classified	classify	VBN
cord-285180-32bxx94u	14	13	into	into	IN
cord-285180-32bxx94u	14	14	the	the	DT
cord-285180-32bxx94u	14	15	functional	functional	JJ
cord-285180-32bxx94u	14	16	groups	group	NNS
cord-285180-32bxx94u	14	17	involved	involve	VBN
cord-285180-32bxx94u	14	18	in	in	IN
cord-285180-32bxx94u	14	19	various	various	JJ
cord-285180-32bxx94u	14	20	cellular	cellular	JJ
cord-285180-32bxx94u	14	21	processes	process	NNS
cord-285180-32bxx94u	14	22	such	such	JJ
cord-285180-32bxx94u	14	23	as	as	IN
cord-285180-32bxx94u	14	24	cell	cell	NN
cord-285180-32bxx94u	14	25	division	division	NN
cord-285180-32bxx94u	14	26	,	,	,
cord-285180-32bxx94u	14	27	metabolism	metabolism	NN
cord-285180-32bxx94u	14	28	,	,	,
cord-285180-32bxx94u	14	29	the	the	DT
cord-285180-32bxx94u	14	30	stress	stress	NN
cord-285180-32bxx94u	14	31	response	response	NN
cord-285180-32bxx94u	14	32	,	,	,
cord-285180-32bxx94u	14	33	protein	protein	NN
cord-285180-32bxx94u	14	34	biosynthesis	biosynthesis	NN
cord-285180-32bxx94u	14	35	and	and	CC
cord-285180-32bxx94u	14	36	transport	transport	NN
cord-285180-32bxx94u	14	37	,	,	,
cord-285180-32bxx94u	14	38	cytoskeleton	cytoskeleton	NN
cord-285180-32bxx94u	14	39	networks	network	NNS
cord-285180-32bxx94u	14	40	and	and	CC
cord-285180-32bxx94u	14	41	cell	cell	NN
cord-285180-32bxx94u	14	42	communication	communication	NN
cord-285180-32bxx94u	14	43	.	.	.
cord-285180-32bxx94u	15	1	Notably	notably	RB
cord-285180-32bxx94u	15	2	,	,	,
cord-285180-32bxx94u	15	3	two	two	CD
cord-285180-32bxx94u	15	4	members	member	NNS
cord-285180-32bxx94u	15	5	of	of	IN
cord-285180-32bxx94u	15	6	the	the	DT
cord-285180-32bxx94u	15	7	heat	heat	NN
cord-285180-32bxx94u	15	8	shock	shock	NN
cord-285180-32bxx94u	15	9	protein	protein	NN
cord-285180-32bxx94u	15	10	70	70	CD
cord-285180-32bxx94u	15	11	family	family	NN
cord-285180-32bxx94u	15	12	were	be	VBD
cord-285180-32bxx94u	15	13	found	find	VBN
cord-285180-32bxx94u	15	14	to	to	TO
cord-285180-32bxx94u	15	15	be	be	VB
cord-285180-32bxx94u	15	16	up	up	RB
cord-285180-32bxx94u	15	17	-	-	HYPH
cord-285180-32bxx94u	15	18	regulated	regulate	VBN
cord-285180-32bxx94u	15	19	in	in	IN
cord-285180-32bxx94u	15	20	PK	PK	NNP
cord-285180-32bxx94u	15	21	-	-	HYPH
cord-285180-32bxx94u	15	22	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	15	23	-	-	HYPH
cord-285180-32bxx94u	15	24	N	n	CD
cord-285180-32bxx94u	15	25	cells	cell	NNS
cord-285180-32bxx94u	15	26	.	.	.
cord-285180-32bxx94u	16	1	These	these	DT
cord-285180-32bxx94u	16	2	proteomic	proteomic	JJ
cord-285180-32bxx94u	16	3	data	datum	NNS
cord-285180-32bxx94u	16	4	will	will	MD
cord-285180-32bxx94u	16	5	provide	provide	VB
cord-285180-32bxx94u	16	6	insights	insight	NNS
cord-285180-32bxx94u	16	7	into	into	IN
cord-285180-32bxx94u	16	8	the	the	DT
cord-285180-32bxx94u	16	9	specific	specific	JJ
cord-285180-32bxx94u	16	10	cellular	cellular	JJ
cord-285180-32bxx94u	16	11	response	response	NN
cord-285180-32bxx94u	16	12	to	to	IN
cord-285180-32bxx94u	16	13	the	the	DT
cord-285180-32bxx94u	16	14	N	n	CD
cord-285180-32bxx94u	16	15	protein	protein	NN
cord-285180-32bxx94u	16	16	during	during	IN
cord-285180-32bxx94u	16	17	PDCoV	pdcov	JJ
cord-285180-32bxx94u	16	18	infection	infection	NN
cord-285180-32bxx94u	16	19	.	.	.
cord-285180-32bxx94u	17	1	Porcine	porcine	JJ
cord-285180-32bxx94u	17	2	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	17	3	(	(	-LRB-
cord-285180-32bxx94u	17	4	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	17	5	)	)	-RRB-
cord-285180-32bxx94u	17	6	is	be	VBZ
cord-285180-32bxx94u	17	7	an	an	DT
cord-285180-32bxx94u	17	8	emerging	emerge	VBG
cord-285180-32bxx94u	17	9	viral	viral	JJ
cord-285180-32bxx94u	17	10	pathogen	pathogen	NN
cord-285180-32bxx94u	17	11	that	that	WDT
cord-285180-32bxx94u	17	12	was	be	VBD
cord-285180-32bxx94u	17	13	first	first	RB
cord-285180-32bxx94u	17	14	reported	report	VBN
cord-285180-32bxx94u	17	15	in	in	IN
cord-285180-32bxx94u	17	16	2012	2012	CD
cord-285180-32bxx94u	17	17	in	in	IN
cord-285180-32bxx94u	17	18	Hong	Hong	NNP
cord-285180-32bxx94u	17	19	Kong	Kong	NNP
cord-285180-32bxx94u	17	20	,	,	,
cord-285180-32bxx94u	18	1	China	China	NNP
cord-285180-32bxx94u	18	2	(	(	-LRB-
cord-285180-32bxx94u	18	3	Woo	woo	UH
cord-285180-32bxx94u	18	4	et	et	FW
cord-285180-32bxx94u	18	5	al	al	NNP
cord-285180-32bxx94u	18	6	.	.	NNP
cord-285180-32bxx94u	18	7	,	,	,
cord-285180-32bxx94u	18	8	2012	2012	CD
cord-285180-32bxx94u	18	9	)	)	-RRB-
cord-285180-32bxx94u	18	10	.	.	.
cord-285180-32bxx94u	19	1	In	in	IN
cord-285180-32bxx94u	19	2	February	February	NNP
cord-285180-32bxx94u	19	3	2014	2014	CD
cord-285180-32bxx94u	19	4	,	,	,
cord-285180-32bxx94u	19	5	the	the	DT
cord-285180-32bxx94u	19	6	detection	detection	NN
cord-285180-32bxx94u	19	7	of	of	IN
cord-285180-32bxx94u	19	8	PDCoV	pdcov	NN
cord-285180-32bxx94u	19	9	was	be	VBD
cord-285180-32bxx94u	19	10	first	first	RB
cord-285180-32bxx94u	19	11	announced	announce	VBN
cord-285180-32bxx94u	19	12	in	in	IN
cord-285180-32bxx94u	19	13	Ohio	Ohio	NNP
cord-285180-32bxx94u	19	14	,	,	,
cord-285180-32bxx94u	19	15	United	United	NNP
cord-285180-32bxx94u	19	16	States	States	NNP
cord-285180-32bxx94u	19	17	,	,	,
cord-285180-32bxx94u	19	18	in	in	IN
cord-285180-32bxx94u	19	19	conjunction	conjunction	NN
cord-285180-32bxx94u	19	20	with	with	IN
cord-285180-32bxx94u	19	21	outbreaks	outbreak	NNS
cord-285180-32bxx94u	19	22	of	of	IN
cord-285180-32bxx94u	19	23	diarrhea	diarrhea	NN
cord-285180-32bxx94u	19	24	without	without	IN
cord-285180-32bxx94u	19	25	other	other	JJ
cord-285180-32bxx94u	19	26	etiologic	etiologic	JJ
cord-285180-32bxx94u	19	27	agents	agent	NNS
cord-285180-32bxx94u	19	28	.	.	.
cord-285180-32bxx94u	20	1	Since	since	IN
cord-285180-32bxx94u	20	2	its	-PRON-	PRP$
cord-285180-32bxx94u	20	3	emergence	emergence	NN
cord-285180-32bxx94u	20	4	,	,	,
cord-285180-32bxx94u	20	5	this	this	DT
cord-285180-32bxx94u	20	6	novel	novel	JJ
cord-285180-32bxx94u	20	7	coronavirus	coronavirus	NN
cord-285180-32bxx94u	20	8	has	have	VBZ
cord-285180-32bxx94u	20	9	been	be	VBN
cord-285180-32bxx94u	20	10	detected	detect	VBN
cord-285180-32bxx94u	20	11	in	in	IN
cord-285180-32bxx94u	20	12	17	17	CD
cord-285180-32bxx94u	20	13	US	US	NNP
cord-285180-32bxx94u	20	14	states	state	NNS
cord-285180-32bxx94u	20	15	,	,	,
cord-285180-32bxx94u	20	16	and	and	CC
cord-285180-32bxx94u	20	17	almost	almost	RB
cord-285180-32bxx94u	20	18	80	80	CD
cord-285180-32bxx94u	20	19	%	%	NN
cord-285180-32bxx94u	20	20	of	of	IN
cord-285180-32bxx94u	20	21	the	the	DT
cord-285180-32bxx94u	20	22	tested	test	VBN
cord-285180-32bxx94u	20	23	samples	sample	NNS
cord-285180-32bxx94u	20	24	corresponded	correspond	VBD
cord-285180-32bxx94u	20	25	to	to	IN
cord-285180-32bxx94u	20	26	cases	case	NNS
cord-285180-32bxx94u	20	27	of	of	IN
cord-285180-32bxx94u	20	28	coinfection	coinfection	NN
cord-285180-32bxx94u	20	29	of	of	IN
cord-285180-32bxx94u	20	30	PDCoV	pdcov	NN
cord-285180-32bxx94u	20	31	with	with	IN
cord-285180-32bxx94u	20	32	other	other	JJ
cord-285180-32bxx94u	20	33	enteric	enteric	JJ
cord-285180-32bxx94u	20	34	viral	viral	JJ
cord-285180-32bxx94u	20	35	pathogens	pathogen	NNS
cord-285180-32bxx94u	20	36	such	such	JJ
cord-285180-32bxx94u	20	37	as	as	IN
cord-285180-32bxx94u	20	38	a	a	DT
cord-285180-32bxx94u	20	39	rotavirus	rotavirus	JJ
cord-285180-32bxx94u	20	40	or	or	CC
cord-285180-32bxx94u	20	41	porcine	porcine	JJ
cord-285180-32bxx94u	20	42	epidemic	epidemic	NN
cord-285180-32bxx94u	20	43	diarrhea	diarrhea	NN
cord-285180-32bxx94u	20	44	virus	virus	NN
cord-285180-32bxx94u	20	45	(	(	-LRB-
cord-285180-32bxx94u	20	46	Li	Li	NNP
cord-285180-32bxx94u	20	47	et	et	NNP
cord-285180-32bxx94u	20	48	al	al	NNP
cord-285180-32bxx94u	20	49	.	.	NNP
cord-285180-32bxx94u	20	50	,	,	,
cord-285180-32bxx94u	20	51	2014	2014	CD
cord-285180-32bxx94u	20	52	;	;	:
cord-285180-32bxx94u	20	53	UTR	UTR	NNP
cord-285180-32bxx94u	20	54	.	.	.
cord-285180-32bxx94u	21	1	ORF1a	ORF1a	NNP
cord-285180-32bxx94u	21	2	/	/	SYM
cord-285180-32bxx94u	21	3	b	b	NNP
cord-285180-32bxx94u	21	4	encompasses	encompass	VBZ
cord-285180-32bxx94u	21	5	two	two	CD
cord-285180-32bxx94u	21	6	-	-	HYPH
cord-285180-32bxx94u	21	7	thirds	third	NNS
cord-285180-32bxx94u	21	8	of	of	IN
cord-285180-32bxx94u	21	9	the	the	DT
cord-285180-32bxx94u	21	10	genome	genome	NN
cord-285180-32bxx94u	21	11	encoding	encode	VBG
cord-285180-32bxx94u	21	12	2	2	CD
cord-285180-32bxx94u	21	13	overlapping	overlap	VBG
cord-285180-32bxx94u	21	14	viral	viral	JJ
cord-285180-32bxx94u	21	15	replicase	replicase	NN
cord-285180-32bxx94u	21	16	polyproteins	polyprotein	NNS
cord-285180-32bxx94u	21	17	,	,	,
cord-285180-32bxx94u	21	18	1a	1a	CD
cord-285180-32bxx94u	21	19	and	and	CC
cord-285180-32bxx94u	21	20	1ab	1ab	NN
cord-285180-32bxx94u	21	21	,	,	,
cord-285180-32bxx94u	21	22	which	which	WDT
cord-285180-32bxx94u	21	23	are	be	VBP
cord-285180-32bxx94u	21	24	then	then	RB
cord-285180-32bxx94u	21	25	proteolytically	proteolytically	RB
cord-285180-32bxx94u	21	26	processed	process	VBN
cord-285180-32bxx94u	21	27	into	into	IN
cord-285180-32bxx94u	21	28	mature	mature	JJ
cord-285180-32bxx94u	21	29	nonstructural	nonstructural	JJ
cord-285180-32bxx94u	21	30	proteins	protein	NNS
cord-285180-32bxx94u	21	31	.	.	.
cord-285180-32bxx94u	22	1	As	as	IN
cord-285180-32bxx94u	22	2	in	in	IN
cord-285180-32bxx94u	22	3	other	other	JJ
cord-285180-32bxx94u	22	4	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	22	5	,	,	,
cord-285180-32bxx94u	22	6	production	production	NN
cord-285180-32bxx94u	22	7	of	of	IN
cord-285180-32bxx94u	22	8	polyproteins	polyproteins	NNP
cord-285180-32bxx94u	22	9	1a	1a	NNP
cord-285180-32bxx94u	22	10	and	and	CC
cord-285180-32bxx94u	22	11	1ab	1ab	NNP
cord-285180-32bxx94u	22	12	requires	require	VBZ
cord-285180-32bxx94u	22	13	a	a	DT
cord-285180-32bxx94u	22	14	−1	−1	NNP
cord-285180-32bxx94u	22	15	ribosomal	ribosomal	JJ
cord-285180-32bxx94u	22	16	frameshift	frameshift	NN
cord-285180-32bxx94u	22	17	during	during	IN
cord-285180-32bxx94u	22	18	translation	translation	NN
cord-285180-32bxx94u	22	19	of	of	IN
cord-285180-32bxx94u	22	20	the	the	DT
cord-285180-32bxx94u	22	21	genomic	genomic	JJ
cord-285180-32bxx94u	22	22	RNA	RNA	NNP
cord-285180-32bxx94u	22	23	.	.	.
cord-285180-32bxx94u	23	1	The	the	DT
cord-285180-32bxx94u	23	2	last	last	JJ
cord-285180-32bxx94u	23	3	third	third	NN
cord-285180-32bxx94u	23	4	of	of	IN
cord-285180-32bxx94u	23	5	the	the	DT
cord-285180-32bxx94u	23	6	genome	genome	NN
cord-285180-32bxx94u	23	7	encodes	encode	VBZ
cord-285180-32bxx94u	23	8	the	the	DT
cord-285180-32bxx94u	23	9	4	4	CD
cord-285180-32bxx94u	23	10	structural	structural	JJ
cord-285180-32bxx94u	23	11	proteins	protein	NNS
cord-285180-32bxx94u	23	12	,	,	,
cord-285180-32bxx94u	23	13	spike	spike	NN
cord-285180-32bxx94u	23	14	(	(	-LRB-
cord-285180-32bxx94u	23	15	S	S	NNP
cord-285180-32bxx94u	23	16	)	)	-RRB-
cord-285180-32bxx94u	23	17	,	,	,
cord-285180-32bxx94u	23	18	envelope	envelope	NN
cord-285180-32bxx94u	23	19	(	(	-LRB-
cord-285180-32bxx94u	23	20	E	E	NNP
cord-285180-32bxx94u	23	21	)	)	-RRB-
cord-285180-32bxx94u	23	22	,	,	,
cord-285180-32bxx94u	23	23	membrane	membrane	NN
cord-285180-32bxx94u	23	24	(	(	-LRB-
cord-285180-32bxx94u	23	25	M	M	NNP
cord-285180-32bxx94u	23	26	)	)	-RRB-
cord-285180-32bxx94u	23	27	,	,	,
cord-285180-32bxx94u	23	28	and	and	CC
cord-285180-32bxx94u	23	29	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	23	30	(	(	-LRB-
cord-285180-32bxx94u	23	31	N	N	NNP
cord-285180-32bxx94u	23	32	)	)	-RRB-
cord-285180-32bxx94u	23	33	,	,	,
cord-285180-32bxx94u	23	34	as	as	RB
cord-285180-32bxx94u	23	35	well	well	RB
cord-285180-32bxx94u	23	36	as	as	IN
cord-285180-32bxx94u	23	37	two	two	CD
cord-285180-32bxx94u	23	38	accessory	accessory	JJ
cord-285180-32bxx94u	23	39	genes	gene	NNS
cord-285180-32bxx94u	23	40	,	,	,
cord-285180-32bxx94u	23	41	nonstructural	nonstructural	JJ
cord-285180-32bxx94u	23	42	gene	gene	NN
cord-285180-32bxx94u	23	43	6	6	CD
cord-285180-32bxx94u	23	44	(	(	-LRB-
cord-285180-32bxx94u	23	45	NS6	NS6	NNP
cord-285180-32bxx94u	23	46	)	)	-RRB-
cord-285180-32bxx94u	23	47	and	and	CC
cord-285180-32bxx94u	23	48	NS7	NS7	NNP
cord-285180-32bxx94u	23	49	gene	gene	NN
cord-285180-32bxx94u	23	50	,	,	,
cord-285180-32bxx94u	23	51	between	between	IN
cord-285180-32bxx94u	23	52	M	M	NNP
cord-285180-32bxx94u	23	53	and	and	CC
cord-285180-32bxx94u	23	54	N	N	NNP
cord-285180-32bxx94u	23	55	,	,	,
cord-285180-32bxx94u	23	56	and	and	CC
cord-285180-32bxx94u	23	57	within	within	IN
cord-285180-32bxx94u	23	58	N	n	CD
cord-285180-32bxx94u	23	59	,	,	,
cord-285180-32bxx94u	23	60	respectively	respectively	RB
cord-285180-32bxx94u	23	61	(	(	-LRB-
cord-285180-32bxx94u	23	62	Lai	Lai	NNP
cord-285180-32bxx94u	23	63	et	et	FW
cord-285180-32bxx94u	23	64	al	al	NNP
cord-285180-32bxx94u	23	65	.	.	NNP
cord-285180-32bxx94u	23	66	,	,	,
cord-285180-32bxx94u	23	67	2007	2007	CD
cord-285180-32bxx94u	23	68	;	;	:
cord-285180-32bxx94u	23	69	Lee	Lee	NNP
cord-285180-32bxx94u	23	70	and	and	CC
cord-285180-32bxx94u	23	71	Lee	Lee	NNP
cord-285180-32bxx94u	23	72	,	,	,
cord-285180-32bxx94u	23	73	2014	2014	CD
cord-285180-32bxx94u	23	74	;	;	:
cord-285180-32bxx94u	23	75	Li	Li	NNP
cord-285180-32bxx94u	23	76	et	et	NNP
cord-285180-32bxx94u	23	77	al	al	NNP
cord-285180-32bxx94u	23	78	.	.	NNP
cord-285180-32bxx94u	23	79	,	,	,
cord-285180-32bxx94u	23	80	2014	2014	CD
cord-285180-32bxx94u	23	81	;	;	:
cord-285180-32bxx94u	23	82	Marthaler	Marthaler	NNP
cord-285180-32bxx94u	23	83	et	et	NNP
cord-285180-32bxx94u	23	84	al	al	NNP
cord-285180-32bxx94u	23	85	.	.	NNP
cord-285180-32bxx94u	23	86	,	,	,
cord-285180-32bxx94u	23	87	2014a	2014a	CD
cord-285180-32bxx94u	23	88	;	;	:
cord-285180-32bxx94u	23	89	Woo	Woo	NNP
cord-285180-32bxx94u	23	90	et	et	NNP
cord-285180-32bxx94u	23	91	al	al	NNP
cord-285180-32bxx94u	23	92	.	.	NNP
cord-285180-32bxx94u	23	93	,	,	,
cord-285180-32bxx94u	23	94	2012	2012	CD
cord-285180-32bxx94u	23	95	)	)	-RRB-
cord-285180-32bxx94u	23	96	.	.	.
cord-285180-32bxx94u	24	1	Among	among	IN
cord-285180-32bxx94u	24	2	the	the	DT
cord-285180-32bxx94u	24	3	structural	structural	JJ
cord-285180-32bxx94u	24	4	proteins	protein	NNS
cord-285180-32bxx94u	24	5	of	of	IN
cord-285180-32bxx94u	24	6	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	24	7	,	,	,
cord-285180-32bxx94u	24	8	the	the	DT
cord-285180-32bxx94u	24	9	N	N	NNP
cord-285180-32bxx94u	24	10	protein	protein	NN
cord-285180-32bxx94u	24	11	is	be	VBZ
cord-285180-32bxx94u	24	12	abundantly	abundantly	RB
cord-285180-32bxx94u	24	13	produced	produce	VBN
cord-285180-32bxx94u	24	14	in	in	IN
cord-285180-32bxx94u	24	15	infected	infected	JJ
cord-285180-32bxx94u	24	16	cells	cell	NNS
cord-285180-32bxx94u	24	17	and	and	CC
cord-285180-32bxx94u	24	18	has	have	VBZ
cord-285180-32bxx94u	24	19	multiple	multiple	JJ
cord-285180-32bxx94u	24	20	functions	function	NNS
cord-285180-32bxx94u	24	21	in	in	IN
cord-285180-32bxx94u	24	22	viral	viral	JJ
cord-285180-32bxx94u	24	23	replication	replication	NN
cord-285180-32bxx94u	24	24	and	and	CC
cord-285180-32bxx94u	24	25	pathogenesis	pathogenesis	NN
cord-285180-32bxx94u	24	26	(	(	-LRB-
cord-285180-32bxx94u	24	27	McBride	McBride	NNP
cord-285180-32bxx94u	24	28	et	et	NNP
cord-285180-32bxx94u	24	29	al	al	NNP
cord-285180-32bxx94u	24	30	.	.	NNP
cord-285180-32bxx94u	24	31	,	,	,
cord-285180-32bxx94u	24	32	2014	2014	CD
cord-285180-32bxx94u	24	33	)	)	-RRB-
cord-285180-32bxx94u	24	34	.	.	.
cord-285180-32bxx94u	25	1	As	as	IN
cord-285180-32bxx94u	25	2	the	the	DT
cord-285180-32bxx94u	25	3	sole	sole	JJ
cord-285180-32bxx94u	25	4	structural	structural	JJ
cord-285180-32bxx94u	25	5	component	component	NN
cord-285180-32bxx94u	25	6	of	of	IN
cord-285180-32bxx94u	25	7	the	the	DT
cord-285180-32bxx94u	25	8	viral	viral	JJ
cord-285180-32bxx94u	25	9	capsid	capsid	NN
cord-285180-32bxx94u	25	10	,	,	,
cord-285180-32bxx94u	25	11	the	the	DT
cord-285180-32bxx94u	25	12	N	N	NNP
cord-285180-32bxx94u	25	13	protein	protein	NN
cord-285180-32bxx94u	25	14	of	of	IN
cord-285180-32bxx94u	25	15	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	25	16	interacts	interact	VBZ
cord-285180-32bxx94u	25	17	with	with	IN
cord-285180-32bxx94u	25	18	the	the	DT
cord-285180-32bxx94u	25	19	nucleic	nucleic	JJ
cord-285180-32bxx94u	25	20	acid	acid	NN
cord-285180-32bxx94u	25	21	and	and	CC
cord-285180-32bxx94u	25	22	itself	-PRON-	PRP
cord-285180-32bxx94u	25	23	for	for	IN
cord-285180-32bxx94u	25	24	selfassociation	selfassociation	NN
cord-285180-32bxx94u	25	25	to	to	TO
cord-285180-32bxx94u	25	26	protect	protect	VB
cord-285180-32bxx94u	25	27	the	the	DT
cord-285180-32bxx94u	25	28	viral	viral	JJ
cord-285180-32bxx94u	25	29	genome	genome	NN
cord-285180-32bxx94u	25	30	from	from	IN
cord-285180-32bxx94u	25	31	extracellular	extracellular	JJ
cord-285180-32bxx94u	25	32	agents	agent	NNS
cord-285180-32bxx94u	25	33	,	,	,
cord-285180-32bxx94u	25	34	serving	serve	VBG
cord-285180-32bxx94u	25	35	as	as	IN
cord-285180-32bxx94u	25	36	the	the	DT
cord-285180-32bxx94u	25	37	critical	critical	JJ
cord-285180-32bxx94u	25	38	basis	basis	NN
cord-285180-32bxx94u	25	39	for	for	IN
cord-285180-32bxx94u	25	40	ribonucleoprotein	ribonucleoprotein	NN
cord-285180-32bxx94u	25	41	(	(	-LRB-
cord-285180-32bxx94u	25	42	RNP	RNP	NNP
cord-285180-32bxx94u	25	43	)	)	-RRB-
cord-285180-32bxx94u	25	44	complexes	complex	NNS
cord-285180-32bxx94u	25	45	during	during	IN
cord-285180-32bxx94u	25	46	virus	virus	NN
cord-285180-32bxx94u	25	47	assembly	assembly	NN
cord-285180-32bxx94u	26	1	(	(	-LRB-
cord-285180-32bxx94u	26	2	McBride	McBride	NNP
cord-285180-32bxx94u	26	3	et	et	NNP
cord-285180-32bxx94u	26	4	al	al	NNP
cord-285180-32bxx94u	26	5	.	.	.
cord-285180-32bxx94u	27	1	,	,	,
cord-285180-32bxx94u	27	2	2014	2014	CD
cord-285180-32bxx94u	27	3	)	)	-RRB-
cord-285180-32bxx94u	27	4	.	.	.
cord-285180-32bxx94u	28	1	The	the	DT
cord-285180-32bxx94u	28	2	entire	entire	JJ
cord-285180-32bxx94u	28	3	life	life	NN
cord-285180-32bxx94u	28	4	cycle	cycle	NN
cord-285180-32bxx94u	28	5	of	of	IN
cord-285180-32bxx94u	28	6	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	28	7	takes	take	VBZ
cord-285180-32bxx94u	28	8	place	place	NN
cord-285180-32bxx94u	28	9	in	in	IN
cord-285180-32bxx94u	28	10	the	the	DT
cord-285180-32bxx94u	28	11	cytoplasm	cytoplasm	NN
cord-285180-32bxx94u	28	12	of	of	IN
cord-285180-32bxx94u	28	13	infected	infected	JJ
cord-285180-32bxx94u	28	14	cells	cell	NNS
cord-285180-32bxx94u	28	15	,	,	,
cord-285180-32bxx94u	28	16	and	and	CC
cord-285180-32bxx94u	28	17	accordingly	accordingly	RB
cord-285180-32bxx94u	28	18	,	,	,
cord-285180-32bxx94u	28	19	the	the	DT
cord-285180-32bxx94u	28	20	N	N	NNP
cord-285180-32bxx94u	28	21	protein	protein	NN
cord-285180-32bxx94u	28	22	is	be	VBZ
cord-285180-32bxx94u	28	23	distributed	distribute	VBN
cord-285180-32bxx94u	28	24	mainly	mainly	RB
cord-285180-32bxx94u	28	25	in	in	IN
cord-285180-32bxx94u	28	26	the	the	DT
cord-285180-32bxx94u	28	27	cytoplasmic	cytoplasmic	JJ
cord-285180-32bxx94u	28	28	compartments	compartment	NNS
cord-285180-32bxx94u	28	29	.	.	.
cord-285180-32bxx94u	29	1	In	in	IN
cord-285180-32bxx94u	29	2	addition	addition	NN
cord-285180-32bxx94u	29	3	to	to	IN
cord-285180-32bxx94u	29	4	their	-PRON-	PRP$
cord-285180-32bxx94u	29	5	cytoplasmic	cytoplasmic	JJ
cord-285180-32bxx94u	29	6	localization	localization	NN
cord-285180-32bxx94u	29	7	,	,	,
cord-285180-32bxx94u	29	8	coronaviral	coronaviral	NNP
cord-285180-32bxx94u	29	9	N	n	CD
cord-285180-32bxx94u	29	10	proteins	protein	NNS
cord-285180-32bxx94u	29	11	are	be	VBP
cord-285180-32bxx94u	29	12	commonly	commonly	RB
cord-285180-32bxx94u	29	13	localized	localize	VBN
cord-285180-32bxx94u	29	14	to	to	IN
cord-285180-32bxx94u	29	15	the	the	DT
cord-285180-32bxx94u	29	16	nucleolus	nucleolus	NN
cord-285180-32bxx94u	29	17	,	,	,
cord-285180-32bxx94u	29	18	suggesting	suggest	VBG
cord-285180-32bxx94u	29	19	their	-PRON-	PRP$
cord-285180-32bxx94u	29	20	non	non	JJ
cord-285180-32bxx94u	29	21	-	-	JJ
cord-285180-32bxx94u	29	22	structural	structural	JJ
cord-285180-32bxx94u	29	23	functions	function	NNS
cord-285180-32bxx94u	29	24	in	in	IN
cord-285180-32bxx94u	29	25	ensuring	ensure	VBG
cord-285180-32bxx94u	29	26	successful	successful	JJ
cord-285180-32bxx94u	29	27	virus	virus	NN
cord-285180-32bxx94u	29	28	infection	infection	NN
cord-285180-32bxx94u	29	29	McBride	McBride	NNP
cord-285180-32bxx94u	29	30	et	et	NNP
cord-285180-32bxx94u	29	31	al	al	NNP
cord-285180-32bxx94u	29	32	.	.	.
cord-285180-32bxx94u	30	1	,	,	,
cord-285180-32bxx94u	30	2	2014	2014	CD
cord-285180-32bxx94u	30	3	)	)	-RRB-
cord-285180-32bxx94u	30	4	.	.	.
cord-285180-32bxx94u	31	1	Although	although	IN
cord-285180-32bxx94u	31	2	a	a	DT
cord-285180-32bxx94u	31	3	variety	variety	NN
cord-285180-32bxx94u	31	4	of	of	IN
cord-285180-32bxx94u	31	5	studies	study	NNS
cord-285180-32bxx94u	31	6	have	have	VBP
cord-285180-32bxx94u	31	7	confirmed	confirm	VBN
cord-285180-32bxx94u	31	8	that	that	IN
cord-285180-32bxx94u	31	9	N	N	NNP
cord-285180-32bxx94u	31	10	possesses	possess	VBZ
cord-285180-32bxx94u	31	11	multifunctional	multifunctional	JJ
cord-285180-32bxx94u	31	12	significance	significance	NN
cord-285180-32bxx94u	31	13	in	in	IN
cord-285180-32bxx94u	31	14	coronavirology	coronavirology	NN
cord-285180-32bxx94u	32	1	(	(	-LRB-
cord-285180-32bxx94u	32	2	McBride	McBride	NNP
cord-285180-32bxx94u	32	3	et	et	NNP
cord-285180-32bxx94u	32	4	al	al	NNP
cord-285180-32bxx94u	32	5	.	.	NNP
cord-285180-32bxx94u	32	6	,	,	,
cord-285180-32bxx94u	32	7	2014	2014	CD
cord-285180-32bxx94u	32	8	)	)	-RRB-
cord-285180-32bxx94u	32	9	,	,	,
cord-285180-32bxx94u	32	10	detailed	detailed	JJ
cord-285180-32bxx94u	32	11	characteristics	characteristic	NNS
cord-285180-32bxx94u	32	12	of	of	IN
cord-285180-32bxx94u	32	13	this	this	DT
cord-285180-32bxx94u	32	14	protein	protein	NN
cord-285180-32bxx94u	32	15	and	and	CC
cord-285180-32bxx94u	32	16	its	-PRON-	PRP$
cord-285180-32bxx94u	32	17	role	role	NN
cord-285180-32bxx94u	32	18	in	in	IN
cord-285180-32bxx94u	32	19	the	the	DT
cord-285180-32bxx94u	32	20	replication	replication	NN
cord-285180-32bxx94u	32	21	of	of	IN
cord-285180-32bxx94u	32	22	PDCoV	pdcov	NN
cord-285180-32bxx94u	32	23	remain	remain	VBP
cord-285180-32bxx94u	32	24	unknown	unknown	JJ
cord-285180-32bxx94u	32	25	.	.	.
cord-285180-32bxx94u	33	1	In	in	IN
cord-285180-32bxx94u	33	2	the	the	DT
cord-285180-32bxx94u	33	3	present	present	JJ
cord-285180-32bxx94u	33	4	study	study	NN
cord-285180-32bxx94u	33	5	,	,	,
cord-285180-32bxx94u	33	6	alterations	alteration	NNS
cord-285180-32bxx94u	33	7	in	in	IN
cord-285180-32bxx94u	33	8	cellular	cellular	JJ
cord-285180-32bxx94u	33	9	gene	gene	NN
cord-285180-32bxx94u	33	10	expression	expression	NN
cord-285180-32bxx94u	33	11	that	that	WDT
cord-285180-32bxx94u	33	12	are	be	VBP
cord-285180-32bxx94u	33	13	caused	cause	VBN
cord-285180-32bxx94u	33	14	by	by	IN
cord-285180-32bxx94u	33	15	the	the	DT
cord-285180-32bxx94u	33	16	N	N	NNP
cord-285180-32bxx94u	33	17	protein	protein	NN
cord-285180-32bxx94u	33	18	were	be	VBD
cord-285180-32bxx94u	33	19	evaluated	evaluate	VBN
cord-285180-32bxx94u	33	20	as	as	IN
cord-285180-32bxx94u	33	21	a	a	DT
cord-285180-32bxx94u	33	22	first	first	JJ
cord-285180-32bxx94u	33	23	step	step	NN
cord-285180-32bxx94u	33	24	toward	toward	IN
cord-285180-32bxx94u	33	25	understanding	understand	VBG
cord-285180-32bxx94u	33	26	the	the	DT
cord-285180-32bxx94u	33	27	biological	biological	JJ
cord-285180-32bxx94u	33	28	role	role	NN
cord-285180-32bxx94u	33	29	of	of	IN
cord-285180-32bxx94u	33	30	the	the	DT
cord-285180-32bxx94u	33	31	N	N	NNP
cord-285180-32bxx94u	33	32	protein	protein	NN
cord-285180-32bxx94u	33	33	in	in	IN
cord-285180-32bxx94u	33	34	PDCoV	pdcov	NN
cord-285180-32bxx94u	33	35	replication	replication	NN
cord-285180-32bxx94u	33	36	.	.	.
cord-285180-32bxx94u	34	1	To	to	TO
cord-285180-32bxx94u	34	2	accomplish	accomplish	VB
cord-285180-32bxx94u	34	3	this	this	DT
cord-285180-32bxx94u	34	4	task	task	NN
cord-285180-32bxx94u	34	5	,	,	,
cord-285180-32bxx94u	34	6	stable	stable	JJ
cord-285180-32bxx94u	34	7	porcine	porcine	JJ
cord-285180-32bxx94u	34	8	-	-	HYPH
cord-285180-32bxx94u	34	9	origin	origin	NN
cord-285180-32bxx94u	34	10	cell	cell	NN
cord-285180-32bxx94u	34	11	lines	line	NNS
cord-285180-32bxx94u	34	12	constitutively	constitutively	RB
cord-285180-32bxx94u	34	13	expressing	express	VBG
cord-285180-32bxx94u	34	14	the	the	DT
cord-285180-32bxx94u	34	15	PDCoV	pdcov	NN
cord-285180-32bxx94u	34	16	N	N	NNP
cord-285180-32bxx94u	34	17	protein	protein	NN
cord-285180-32bxx94u	34	18	were	be	VBD
cord-285180-32bxx94u	34	19	generated	generate	VBN
cord-285180-32bxx94u	34	20	and	and	CC
cord-285180-32bxx94u	34	21	characterized	characterize	VBN
cord-285180-32bxx94u	34	22	in	in	IN
cord-285180-32bxx94u	34	23	this	this	DT
cord-285180-32bxx94u	34	24	study	study	NN
cord-285180-32bxx94u	34	25	.	.	.
cord-285180-32bxx94u	35	1	Changes	change	NNS
cord-285180-32bxx94u	35	2	in	in	IN
cord-285180-32bxx94u	35	3	expression	expression	NN
cord-285180-32bxx94u	35	4	patterns	pattern	NNS
cord-285180-32bxx94u	35	5	of	of	IN
cord-285180-32bxx94u	35	6	various	various	JJ
cord-285180-32bxx94u	35	7	cellular	cellular	JJ
cord-285180-32bxx94u	35	8	proteins	protein	NNS
cord-285180-32bxx94u	35	9	in	in	IN
cord-285180-32bxx94u	35	10	the	the	DT
cord-285180-32bxx94u	35	11	N	n	CD
cord-285180-32bxx94u	35	12	protein	protein	NN
cord-285180-32bxx94u	35	13	-	-	HYPH
cord-285180-32bxx94u	35	14	expressing	express	VBG
cord-285180-32bxx94u	35	15	porcine	porcine	JJ
cord-285180-32bxx94u	35	16	cells	cell	NNS
cord-285180-32bxx94u	35	17	in	in	IN
cord-285180-32bxx94u	35	18	comparison	comparison	NN
cord-285180-32bxx94u	35	19	with	with	IN
cord-285180-32bxx94u	35	20	control	control	NN
cord-285180-32bxx94u	35	21	cells	cell	NNS
cord-285180-32bxx94u	35	22	were	be	VBD
cord-285180-32bxx94u	35	23	examined	examine	VBN
cord-285180-32bxx94u	35	24	by	by	IN
cord-285180-32bxx94u	35	25	proteomic	proteomic	JJ
cord-285180-32bxx94u	35	26	analysis	analysis	NN
cord-285180-32bxx94u	35	27	at	at	IN
cord-285180-32bxx94u	35	28	different	different	JJ
cord-285180-32bxx94u	35	29	time	time	NN
cord-285180-32bxx94u	35	30	points	point	NNS
cord-285180-32bxx94u	35	31	.	.	.
cord-285180-32bxx94u	36	1	Our	-PRON-	PRP$
cord-285180-32bxx94u	36	2	proteomic	proteomic	JJ
cord-285180-32bxx94u	36	3	data	datum	NNS
cord-285180-32bxx94u	36	4	are	be	VBP
cord-285180-32bxx94u	36	5	expected	expect	VBN
cord-285180-32bxx94u	36	6	to	to	TO
cord-285180-32bxx94u	36	7	provide	provide	VB
cord-285180-32bxx94u	36	8	novel	novel	JJ
cord-285180-32bxx94u	36	9	information	information	NN
cord-285180-32bxx94u	36	10	for	for	IN
cord-285180-32bxx94u	36	11	better	well	JJR
cord-285180-32bxx94u	36	12	knowledge	knowledge	NN
cord-285180-32bxx94u	36	13	of	of	IN
cord-285180-32bxx94u	36	14	the	the	DT
cord-285180-32bxx94u	36	15	properties	property	NNS
cord-285180-32bxx94u	36	16	and	and	CC
cord-285180-32bxx94u	36	17	functions	function	NNS
cord-285180-32bxx94u	36	18	of	of	IN
cord-285180-32bxx94u	36	19	the	the	DT
cord-285180-32bxx94u	36	20	N	N	NNP
cord-285180-32bxx94u	36	21	protein	protein	NN
cord-285180-32bxx94u	36	22	during	during	IN
cord-285180-32bxx94u	36	23	PDCoV	pdcov	JJ
cord-285180-32bxx94u	36	24	infection	infection	NN
cord-285180-32bxx94u	36	25	.	.	.
cord-285180-32bxx94u	37	1	HEK-293	HEK-293	NNP
cord-285180-32bxx94u	38	1	T	T	NNP
cord-285180-32bxx94u	38	2	cells	cell	NNS
cord-285180-32bxx94u	38	3	(	(	-LRB-
cord-285180-32bxx94u	38	4	CRL-1573	CRL-1573	NNP
cord-285180-32bxx94u	38	5	)	)	-RRB-
cord-285180-32bxx94u	38	6	were	be	VBD
cord-285180-32bxx94u	38	7	purchased	purchase	VBN
cord-285180-32bxx94u	38	8	from	from	IN
cord-285180-32bxx94u	38	9	the	the	DT
cord-285180-32bxx94u	38	10	American	American	NNP
cord-285180-32bxx94u	38	11	Type	Type	NNP
cord-285180-32bxx94u	38	12	Culture	Culture	NNP
cord-285180-32bxx94u	38	13	Collection	Collection	NNP
cord-285180-32bxx94u	38	14	(	(	-LRB-
cord-285180-32bxx94u	38	15	ATCC	ATCC	NNP
cord-285180-32bxx94u	38	16	,	,	,
cord-285180-32bxx94u	38	17	Manassas	Manassas	NNP
cord-285180-32bxx94u	38	18	,	,	,
cord-285180-32bxx94u	38	19	VA	VA	NNP
cord-285180-32bxx94u	38	20	)	)	-RRB-
cord-285180-32bxx94u	38	21	and	and	CC
cord-285180-32bxx94u	38	22	cultured	culture	VBN
cord-285180-32bxx94u	38	23	in	in	IN
cord-285180-32bxx94u	38	24	Dulbecco	Dulbecco	NNP
cord-285180-32bxx94u	38	25	's	's	POS
cord-285180-32bxx94u	38	26	modified	modify	VBN
cord-285180-32bxx94u	38	27	Eagle	Eagle	NNP
cord-285180-32bxx94u	38	28	medium	medium	NN
cord-285180-32bxx94u	38	29	(	(	-LRB-
cord-285180-32bxx94u	38	30	DMEM	DMEM	NNP
cord-285180-32bxx94u	38	31	)	)	-RRB-
cord-285180-32bxx94u	38	32	with	with	IN
cord-285180-32bxx94u	38	33	high	high	JJ
cord-285180-32bxx94u	38	34	glucose	glucose	NN
cord-285180-32bxx94u	38	35	(	(	-LRB-
cord-285180-32bxx94u	38	36	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	38	37	,	,	,
cord-285180-32bxx94u	38	38	Carlsbad	Carlsbad	NNP
cord-285180-32bxx94u	38	39	,	,	,
cord-285180-32bxx94u	38	40	CA	CA	NNP
cord-285180-32bxx94u	38	41	)	)	-RRB-
cord-285180-32bxx94u	38	42	with	with	IN
cord-285180-32bxx94u	38	43	10	10	CD
cord-285180-32bxx94u	38	44	%	%	NN
cord-285180-32bxx94u	38	45	fetal	fetal	JJ
cord-285180-32bxx94u	38	46	bovine	bovine	JJ
cord-285180-32bxx94u	38	47	serum	serum	NN
cord-285180-32bxx94u	38	48	(	(	-LRB-
cord-285180-32bxx94u	38	49	FBS	FBS	NNP
cord-285180-32bxx94u	38	50	;	;	:
cord-285180-32bxx94u	38	51	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	38	52	)	)	-RRB-
cord-285180-32bxx94u	38	53	and	and	CC
cord-285180-32bxx94u	38	54	antibiotic	antibiotic	JJ
cord-285180-32bxx94u	38	55	-	-	HYPH
cord-285180-32bxx94u	38	56	antimycotic	antimycotic	JJ
cord-285180-32bxx94u	38	57	solutions	solution	NNS
cord-285180-32bxx94u	38	58	(	(	-LRB-
cord-285180-32bxx94u	38	59	100×	100×	CD
cord-285180-32bxx94u	38	60	;	;	:
cord-285180-32bxx94u	38	61	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	38	62	)	)	-RRB-
cord-285180-32bxx94u	38	63	.	.	.
cord-285180-32bxx94u	39	1	PK-15	pk-15	JJ
cord-285180-32bxx94u	39	2	cells	cell	NNS
cord-285180-32bxx94u	39	3	were	be	VBD
cord-285180-32bxx94u	39	4	grown	grow	VBN
cord-285180-32bxx94u	39	5	in	in	IN
cord-285180-32bxx94u	39	6	RPMI	RPMI	NNP
cord-285180-32bxx94u	39	7	1640	1640	CD
cord-285180-32bxx94u	39	8	medium	medium	NN
cord-285180-32bxx94u	39	9	(	(	-LRB-
cord-285180-32bxx94u	39	10	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	39	11	)	)	-RRB-
cord-285180-32bxx94u	39	12	supplemented	supplement	VBD
cord-285180-32bxx94u	39	13	with	with	IN
cord-285180-32bxx94u	39	14	10	10	CD
cord-285180-32bxx94u	39	15	%	%	NN
cord-285180-32bxx94u	39	16	FBS	FBS	NNP
cord-285180-32bxx94u	39	17	and	and	CC
cord-285180-32bxx94u	39	18	antibiotic	antibiotic	JJ
cord-285180-32bxx94u	39	19	-	-	HYPH
cord-285180-32bxx94u	39	20	antimycotic	antimycotic	JJ
cord-285180-32bxx94u	39	21	solutions	solution	NNS
cord-285180-32bxx94u	39	22	(	(	-LRB-
cord-285180-32bxx94u	39	23	100×	100×	CD
cord-285180-32bxx94u	39	24	)	)	-RRB-
cord-285180-32bxx94u	39	25	.	.	.
cord-285180-32bxx94u	40	1	The	the	DT
cord-285180-32bxx94u	40	2	cells	cell	NNS
cord-285180-32bxx94u	40	3	were	be	VBD
cord-285180-32bxx94u	40	4	maintained	maintain	VBN
cord-285180-32bxx94u	40	5	at	at	IN
cord-285180-32bxx94u	40	6	37	37	CD
cord-285180-32bxx94u	40	7	•	•	NN
cord-285180-32bxx94u	40	8	C	c	NN
cord-285180-32bxx94u	40	9	in	in	IN
cord-285180-32bxx94u	40	10	an	an	DT
cord-285180-32bxx94u	40	11	atmosphere	atmosphere	NN
cord-285180-32bxx94u	40	12	of	of	IN
cord-285180-32bxx94u	40	13	humidified	humidified	JJ
cord-285180-32bxx94u	40	14	air	air	NN
cord-285180-32bxx94u	40	15	containing	contain	VBG
cord-285180-32bxx94u	40	16	5	5	CD
cord-285180-32bxx94u	40	17	%	%	NN
cord-285180-32bxx94u	40	18	CO	co	NN
cord-285180-32bxx94u	40	19	2	2	CD
cord-285180-32bxx94u	40	20	.	.	.
cord-285180-32bxx94u	41	1	PAM	PAM	NNP
cord-285180-32bxx94u	41	2	-	-	HYPH
cord-285180-32bxx94u	41	3	pCD163-N	pcd163-n	NN
cord-285180-32bxx94u	41	4	cells	cell	NNS
cord-285180-32bxx94u	41	5	that	that	WDT
cord-285180-32bxx94u	41	6	stably	stably	RB
cord-285180-32bxx94u	41	7	express	express	VBP
cord-285180-32bxx94u	41	8	the	the	DT
cord-285180-32bxx94u	41	9	N	n	CD
cord-285180-32bxx94u	41	10	protein	protein	NN
cord-285180-32bxx94u	41	11	of	of	IN
cord-285180-32bxx94u	41	12	porcine	porcine	JJ
cord-285180-32bxx94u	41	13	reproductive	reproductive	JJ
cord-285180-32bxx94u	41	14	and	and	CC
cord-285180-32bxx94u	41	15	respiratory	respiratory	JJ
cord-285180-32bxx94u	41	16	syndrome	syndrome	NN
cord-285180-32bxx94u	41	17	virus	virus	NN
cord-285180-32bxx94u	41	18	(	(	-LRB-
cord-285180-32bxx94u	41	19	PRRSV	PRRSV	NNP
cord-285180-32bxx94u	41	20	;	;	:
cord-285180-32bxx94u	42	1	Sagong	Sagong	NNP
cord-285180-32bxx94u	42	2	and	and	CC
cord-285180-32bxx94u	42	3	Lee	Lee	NNP
cord-285180-32bxx94u	42	4	,	,	,
cord-285180-32bxx94u	42	5	2010	2010	CD
cord-285180-32bxx94u	42	6	)	)	-RRB-
cord-285180-32bxx94u	42	7	were	be	VBD
cord-285180-32bxx94u	42	8	cultured	culture	VBN
cord-285180-32bxx94u	42	9	in	in	IN
cord-285180-32bxx94u	42	10	RPMI	RPMI	NNP
cord-285180-32bxx94u	42	11	1640	1640	CD
cord-285180-32bxx94u	42	12	medium	medium	NN
cord-285180-32bxx94u	42	13	(	(	-LRB-
cord-285180-32bxx94u	42	14	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	42	15	)	)	-RRB-
cord-285180-32bxx94u	42	16	supplemented	supplement	VBD
cord-285180-32bxx94u	42	17	with	with	IN
cord-285180-32bxx94u	42	18	10	10	CD
cord-285180-32bxx94u	42	19	%	%	NN
cord-285180-32bxx94u	42	20	FBS	FBS	NNP
cord-285180-32bxx94u	42	21	,	,	,
cord-285180-32bxx94u	42	22	antibiotic	antibiotic	JJ
cord-285180-32bxx94u	42	23	-	-	HYPH
cord-285180-32bxx94u	42	24	antimycotic	antimycotic	JJ
cord-285180-32bxx94u	42	25	solutions	solution	NNS
cord-285180-32bxx94u	42	26	(	(	-LRB-
cord-285180-32bxx94u	42	27	100×	100×	CD
cord-285180-32bxx94u	42	28	)	)	-RRB-
cord-285180-32bxx94u	42	29	,	,	,
cord-285180-32bxx94u	42	30	10	10	CD
cord-285180-32bxx94u	42	31	mM	mm	CD
cord-285180-32bxx94u	42	32	HEPES	HEPES	NNP
cord-285180-32bxx94u	42	33	(	(	-LRB-
cord-285180-32bxx94u	42	34	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	42	35	)	)	-RRB-
cord-285180-32bxx94u	42	36	,	,	,
cord-285180-32bxx94u	42	37	1	1	CD
cord-285180-32bxx94u	42	38	mM	mm	CD
cord-285180-32bxx94u	42	39	sodium	sodium	NN
cord-285180-32bxx94u	42	40	pyruvate	pyruvate	NN
cord-285180-32bxx94u	42	41	(	(	-LRB-
cord-285180-32bxx94u	42	42	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	42	43	)	)	-RRB-
cord-285180-32bxx94u	42	44	,	,	,
cord-285180-32bxx94u	42	45	and	and	CC
cord-285180-32bxx94u	42	46	nonessential	nonessential	JJ
cord-285180-32bxx94u	42	47	amino	amino	NN
cord-285180-32bxx94u	42	48	acids	acid	NNS
cord-285180-32bxx94u	42	49	(	(	-LRB-
cord-285180-32bxx94u	42	50	100×	100×	CD
cord-285180-32bxx94u	42	51	;	;	:
cord-285180-32bxx94u	42	52	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	42	53	)	)	-RRB-
cord-285180-32bxx94u	42	54	in	in	IN
cord-285180-32bxx94u	42	55	the	the	DT
cord-285180-32bxx94u	42	56	presence	presence	NN
cord-285180-32bxx94u	42	57	of	of	IN
cord-285180-32bxx94u	42	58	50	50	CD
cord-285180-32bxx94u	42	59	g	g	NN
cord-285180-32bxx94u	42	60	/	/	SYM
cord-285180-32bxx94u	42	61	ml	ml	NNP
cord-285180-32bxx94u	42	62	Zeocin	Zeocin	NNP
cord-285180-32bxx94u	42	63	(	(	-LRB-
cord-285180-32bxx94u	42	64	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	42	65	)	)	-RRB-
cord-285180-32bxx94u	42	66	and	and	CC
cord-285180-32bxx94u	42	67	200	200	CD
cord-285180-32bxx94u	42	68	g	g	NN
cord-285180-32bxx94u	42	69	/	/	SYM
cord-285180-32bxx94u	42	70	ml	ml	NN
cord-285180-32bxx94u	42	71	G418	G418	NNP
cord-285180-32bxx94u	42	72	(	(	-LRB-
cord-285180-32bxx94u	42	73	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	42	74	)	)	-RRB-
cord-285180-32bxx94u	42	75	.	.	.
cord-285180-32bxx94u	43	1	The	the	DT
cord-285180-32bxx94u	43	2	anti	anti	JJ
cord-285180-32bxx94u	43	3	-	-	JJ
cord-285180-32bxx94u	43	4	PRRSV	PRRSV	NNP
cord-285180-32bxx94u	43	5	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	43	6	(	(	-LRB-
cord-285180-32bxx94u	43	7	N	n	CD
cord-285180-32bxx94u	43	8	)	)	-RRB-
cord-285180-32bxx94u	43	9	monoclonal	monoclonal	JJ
cord-285180-32bxx94u	43	10	antibody	antibody	NN
cord-285180-32bxx94u	43	11	(	(	-LRB-
cord-285180-32bxx94u	43	12	MAb	MAb	NNS
cord-285180-32bxx94u	43	13	)	)	-RRB-
cord-285180-32bxx94u	43	14	and	and	CC
cord-285180-32bxx94u	43	15	anti	anti	JJ
cord-285180-32bxx94u	43	16	-	-	JJ
cord-285180-32bxx94u	43	17	myc	myc	JJ
cord-285180-32bxx94u	43	18	MAb	MAb	NNS
cord-285180-32bxx94u	43	19	were	be	VBD
cord-285180-32bxx94u	43	20	purchased	purchase	VBN
cord-285180-32bxx94u	43	21	from	from	IN
cord-285180-32bxx94u	43	22	MEDIAN	MEDIAN	NNP
cord-285180-32bxx94u	43	23	Diagnostics	diagnostic	NNS
cord-285180-32bxx94u	43	24	(	(	-LRB-
cord-285180-32bxx94u	43	25	Chuncheon	Chuncheon	NNP
cord-285180-32bxx94u	43	26	,	,	,
cord-285180-32bxx94u	43	27	South	South	NNP
cord-285180-32bxx94u	43	28	Korea	Korea	NNP
cord-285180-32bxx94u	43	29	)	)	-RRB-
cord-285180-32bxx94u	43	30	and	and	CC
cord-285180-32bxx94u	43	31	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	43	32	,	,	,
cord-285180-32bxx94u	43	33	respectively	respectively	RB
cord-285180-32bxx94u	43	34	.	.	.
cord-285180-32bxx94u	44	1	Antibodies	antibody	NNS
cord-285180-32bxx94u	44	2	to	to	IN
cord-285180-32bxx94u	44	3	the	the	DT
cord-285180-32bxx94u	44	4	6×	6×	CD
cord-285180-32bxx94u	44	5	histidine	histidine	NN
cord-285180-32bxx94u	44	6	tag	tag	NN
cord-285180-32bxx94u	44	7	,	,	,
cord-285180-32bxx94u	44	8	glucose	glucose	NN
cord-285180-32bxx94u	44	9	-	-	HYPH
cord-285180-32bxx94u	44	10	regulated	regulate	VBN
cord-285180-32bxx94u	44	11	protein	protein	NN
cord-285180-32bxx94u	44	12	78	78	CD
cord-285180-32bxx94u	44	13	(	(	-LRB-
cord-285180-32bxx94u	44	14	GRP78	GRP78	NNP
cord-285180-32bxx94u	44	15	)	)	-RRB-
cord-285180-32bxx94u	44	16	,	,	,
cord-285180-32bxx94u	44	17	heat	heat	NN
cord-285180-32bxx94u	44	18	shock	shock	NN
cord-285180-32bxx94u	44	19	cognate	cognate	JJ
cord-285180-32bxx94u	44	20	70-kDa	70-kda	CD
cord-285180-32bxx94u	44	21	protein	protein	NN
cord-285180-32bxx94u	44	22	(	(	-LRB-
cord-285180-32bxx94u	44	23	HSC70	HSC70	NNP
cord-285180-32bxx94u	44	24	)	)	-RRB-
cord-285180-32bxx94u	44	25	,	,	.
cord-285180-32bxx94u	45	1	␤	␤	.
cord-285180-32bxx94u	46	1	-actin	-actin	NFP
cord-285180-32bxx94u	46	2	,	,	,
cord-285180-32bxx94u	47	1	␣	␣	NNP
cord-285180-32bxx94u	47	2	-tubulin	-tubulin	NNP
cord-285180-32bxx94u	47	3	,	,	,
cord-285180-32bxx94u	47	4	and	and	CC
cord-285180-32bxx94u	47	5	Sp1	Sp1	NNP
cord-285180-32bxx94u	47	6	were	be	VBD
cord-285180-32bxx94u	47	7	purchased	purchase	VBN
cord-285180-32bxx94u	47	8	from	from	IN
cord-285180-32bxx94u	47	9	Santa	Santa	NNP
cord-285180-32bxx94u	47	10	Cruz	Cruz	NNP
cord-285180-32bxx94u	47	11	Biotechnology	Biotechnology	NNP
cord-285180-32bxx94u	47	12	(	(	-LRB-
cord-285180-32bxx94u	47	13	Santa	Santa	NNP
cord-285180-32bxx94u	47	14	Cruz	Cruz	NNP
cord-285180-32bxx94u	47	15	,	,	,
cord-285180-32bxx94u	47	16	CA	CA	NNP
cord-285180-32bxx94u	47	17	)	)	-RRB-
cord-285180-32bxx94u	47	18	.	.	.
cord-285180-32bxx94u	48	1	DNA	dna	NN
cord-285180-32bxx94u	48	2	manipulation	manipulation	NN
cord-285180-32bxx94u	48	3	and	and	CC
cord-285180-32bxx94u	48	4	cloning	cloning	NN
cord-285180-32bxx94u	48	5	were	be	VBD
cord-285180-32bxx94u	48	6	performed	perform	VBN
cord-285180-32bxx94u	48	7	according	accord	VBG
cord-285180-32bxx94u	48	8	to	to	IN
cord-285180-32bxx94u	48	9	standard	standard	JJ
cord-285180-32bxx94u	48	10	procedures	procedure	NNS
cord-285180-32bxx94u	48	11	(	(	-LRB-
cord-285180-32bxx94u	48	12	Sambrook	Sambrook	NNP
cord-285180-32bxx94u	48	13	and	and	CC
cord-285180-32bxx94u	48	14	Russell	Russell	NNP
cord-285180-32bxx94u	48	15	,	,	,
cord-285180-32bxx94u	48	16	2001	2001	CD
cord-285180-32bxx94u	48	17	)	)	-RRB-
cord-285180-32bxx94u	48	18	.	.	.
cord-285180-32bxx94u	49	1	The	the	DT
cord-285180-32bxx94u	49	2	Escherichia	Escherichia	NNP
cord-285180-32bxx94u	49	3	coli	coli	NNS
cord-285180-32bxx94u	49	4	strain	strain	NN
cord-285180-32bxx94u	50	1	DH5	DH5	NNP
cord-285180-32bxx94u	50	2	␣	␣	NNP
cord-285180-32bxx94u	50	3	(	(	-LRB-
cord-285180-32bxx94u	50	4	RBC	RBC	NNP
cord-285180-32bxx94u	50	5	Bioscience	Bioscience	NNP
cord-285180-32bxx94u	50	6	,	,	,
cord-285180-32bxx94u	50	7	Taiwan	Taiwan	NNP
cord-285180-32bxx94u	50	8	)	)	-RRB-
cord-285180-32bxx94u	50	9	was	be	VBD
cord-285180-32bxx94u	50	10	used	use	VBN
cord-285180-32bxx94u	50	11	as	as	IN
cord-285180-32bxx94u	50	12	the	the	DT
cord-285180-32bxx94u	50	13	host	host	NN
cord-285180-32bxx94u	50	14	for	for	IN
cord-285180-32bxx94u	50	15	general	general	JJ
cord-285180-32bxx94u	50	16	cloning	cloning	NN
cord-285180-32bxx94u	50	17	.	.	.
cord-285180-32bxx94u	51	1	The	the	DT
cord-285180-32bxx94u	51	2	full	full	JJ
cord-285180-32bxx94u	51	3	-	-	HYPH
cord-285180-32bxx94u	51	4	length	length	NN
cord-285180-32bxx94u	51	5	N	n	CD
cord-285180-32bxx94u	51	6	gene	gene	NN
cord-285180-32bxx94u	51	7	was	be	VBD
cord-285180-32bxx94u	51	8	amplified	amplify	VBN
cord-285180-32bxx94u	51	9	from	from	IN
cord-285180-32bxx94u	51	10	the	the	DT
cord-285180-32bxx94u	51	11	PDCoV	pdcov	NN
cord-285180-32bxx94u	51	12	KNU14	KNU14	NNP
cord-285180-32bxx94u	51	13	-	-	HYPH
cord-285180-32bxx94u	51	14	04	04	CD
cord-285180-32bxx94u	51	15	strain	strain	NN
cord-285180-32bxx94u	51	16	(	(	-LRB-
cord-285180-32bxx94u	51	17	Lee	Lee	NNP
cord-285180-32bxx94u	51	18	and	and	CC
cord-285180-32bxx94u	51	19	Lee	Lee	NNP
cord-285180-32bxx94u	51	20	,	,	,
cord-285180-32bxx94u	51	21	2014	2014	CD
cord-285180-32bxx94u	51	22	)	)	-RRB-
cord-285180-32bxx94u	51	23	with	with	IN
cord-285180-32bxx94u	51	24	the	the	DT
cord-285180-32bxx94u	51	25	following	follow	VBG
cord-285180-32bxx94u	51	26	primer	primer	NN
cord-285180-32bxx94u	51	27	pair	pair	NN
cord-285180-32bxx94u	51	28	:	:	:
cord-285180-32bxx94u	51	29	KNU14	knu14	NN
cord-285180-32bxx94u	51	30	-	-	HYPH
cord-285180-32bxx94u	51	31	04-N	04-n	CD
cord-285180-32bxx94u	51	32	-	-	HYPH
cord-285180-32bxx94u	51	33	Fwd	fwd	NN
cord-285180-32bxx94u	51	34	(	(	-LRB-
cord-285180-32bxx94u	51	35	5	5	CD
cord-285180-32bxx94u	51	36	-GCCGGTCGACATGGCTGCACCAGTAG-3	-GCCGGTCGACATGGCTGCACCAGTAG-3	NNPS
cord-285180-32bxx94u	51	37	)	)	-RRB-
cord-285180-32bxx94u	51	38	and	and	CC
cord-285180-32bxx94u	51	39	KNU14	KNU14	NNP
cord-285180-32bxx94u	51	40	-	-	HYPH
cord-285180-32bxx94u	51	41	04-N	04-n	CD
cord-285180-32bxx94u	51	42	-	-	HYPH
cord-285180-32bxx94u	51	43	Rev	Rev	NNP
cord-285180-32bxx94u	51	44	(	(	-LRB-
cord-285180-32bxx94u	51	45	5	5	CD
cord-285180-32bxx94u	51	46	-CGGCTCTAGACGCTGCTGATTCCTGC-3	-CGGCTCTAGACGCTGCTGATTCCTGC-3	NNP
cord-285180-32bxx94u	51	47	)	)	-RRB-
cord-285180-32bxx94u	51	48	,	,	,
cord-285180-32bxx94u	51	49	where	where	WRB
cord-285180-32bxx94u	51	50	underlines	underline	NNS
cord-285180-32bxx94u	51	51	indicate	indicate	VBP
cord-285180-32bxx94u	51	52	the	the	DT
cord-285180-32bxx94u	51	53	SalI	SalI	NNP
cord-285180-32bxx94u	51	54	and	and	CC
cord-285180-32bxx94u	51	55	XbaI	XbaI	NNP
cord-285180-32bxx94u	51	56	restriction	restriction	NN
cord-285180-32bxx94u	51	57	enzyme	enzyme	NN
cord-285180-32bxx94u	51	58	sites	site	NNS
cord-285180-32bxx94u	51	59	,	,	,
cord-285180-32bxx94u	51	60	respectively	respectively	RB
cord-285180-32bxx94u	51	61	.	.	.
cord-285180-32bxx94u	52	1	The	the	DT
cord-285180-32bxx94u	52	2	PCR	PCR	NNP
cord-285180-32bxx94u	52	3	amplicon	amplicon	NN
cord-285180-32bxx94u	52	4	was	be	VBD
cord-285180-32bxx94u	52	5	initially	initially	RB
cord-285180-32bxx94u	52	6	inserted	insert	VBN
cord-285180-32bxx94u	52	7	into	into	IN
cord-285180-32bxx94u	52	8	the	the	DT
cord-285180-32bxx94u	52	9	pBudCE4.1	pbudce4.1	JJ
cord-285180-32bxx94u	52	10	vector	vector	NN
cord-285180-32bxx94u	52	11	(	(	-LRB-
cord-285180-32bxx94u	52	12	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	52	13	)	)	-RRB-
cord-285180-32bxx94u	52	14	that	that	WDT
cord-285180-32bxx94u	52	15	contains	contain	VBZ
cord-285180-32bxx94u	52	16	a	a	DT
cord-285180-32bxx94u	52	17	myc	myc	NNP
cord-285180-32bxx94u	52	18	epitope	epitope	NN
cord-285180-32bxx94u	52	19	and	and	CC
cord-285180-32bxx94u	52	20	6	6	CD
cord-285180-32bxx94u	52	21	repetitive	repetitive	JJ
cord-285180-32bxx94u	52	22	histidine	histidine	NN
cord-285180-32bxx94u	52	23	codons	codon	NNS
cord-285180-32bxx94u	52	24	,	,	,
cord-285180-32bxx94u	52	25	and	and	CC
cord-285180-32bxx94u	52	26	the	the	DT
cord-285180-32bxx94u	52	27	resulting	result	VBG
cord-285180-32bxx94u	52	28	plasmid	plasmid	JJ
cord-285180-32bxx94u	52	29	pBud	pBud	NNP
cord-285180-32bxx94u	52	30	-	-	HYPH
cord-285180-32bxx94u	52	31	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	52	32	-	-	HYPH
cord-285180-32bxx94u	52	33	N	N	NNP
cord-285180-32bxx94u	52	34	was	be	VBD
cord-285180-32bxx94u	52	35	verified	verify	VBN
cord-285180-32bxx94u	52	36	by	by	IN
cord-285180-32bxx94u	52	37	nucleotide	nucleotide	JJ
cord-285180-32bxx94u	52	38	sequencing	sequencing	NN
cord-285180-32bxx94u	52	39	.	.	.
cord-285180-32bxx94u	53	1	Because	because	IN
cord-285180-32bxx94u	53	2	the	the	DT
cord-285180-32bxx94u	53	3	PDCoV	pdcov	NN
cord-285180-32bxx94u	53	4	genome	genome	NN
cord-285180-32bxx94u	53	5	contains	contain	VBZ
cord-285180-32bxx94u	53	6	one	one	CD
cord-285180-32bxx94u	53	7	accessory	accessory	NN
cord-285180-32bxx94u	53	8	NS7	NS7	NNP
cord-285180-32bxx94u	53	9	gene	gene	NN
cord-285180-32bxx94u	53	10	within	within	IN
cord-285180-32bxx94u	53	11	the	the	DT
cord-285180-32bxx94u	53	12	N	n	CD
cord-285180-32bxx94u	53	13	gene	gene	NN
cord-285180-32bxx94u	53	14	in	in	IN
cord-285180-32bxx94u	53	15	a	a	DT
cord-285180-32bxx94u	53	16	different	different	JJ
cord-285180-32bxx94u	53	17	reading	reading	NN
cord-285180-32bxx94u	53	18	frame	frame	NN
cord-285180-32bxx94u	53	19	,	,	,
cord-285180-32bxx94u	53	20	the	the	DT
cord-285180-32bxx94u	53	21	presence	presence	NN
cord-285180-32bxx94u	53	22	of	of	IN
cord-285180-32bxx94u	53	23	NS7	NS7	NNP
cord-285180-32bxx94u	53	24	could	could	MD
cord-285180-32bxx94u	53	25	affect	affect	VB
cord-285180-32bxx94u	53	26	our	-PRON-	PRP$
cord-285180-32bxx94u	53	27	functional	functional	JJ
cord-285180-32bxx94u	53	28	studies	study	NNS
cord-285180-32bxx94u	53	29	of	of	IN
cord-285180-32bxx94u	53	30	the	the	DT
cord-285180-32bxx94u	53	31	PDCoV	pdcov	NN
cord-285180-32bxx94u	53	32	N	n	CD
cord-285180-32bxx94u	53	33	protein	protein	NN
cord-285180-32bxx94u	53	34	.	.	.
cord-285180-32bxx94u	54	1	To	to	TO
cord-285180-32bxx94u	54	2	prevent	prevent	VB
cord-285180-32bxx94u	54	3	any	any	DT
cord-285180-32bxx94u	54	4	such	such	JJ
cord-285180-32bxx94u	54	5	side	side	NN
cord-285180-32bxx94u	54	6	effects	effect	NNS
cord-285180-32bxx94u	54	7	,	,	,
cord-285180-32bxx94u	54	8	the	the	DT
cord-285180-32bxx94u	54	9	translation	translation	NN
cord-285180-32bxx94u	54	10	initiation	initiation	NN
cord-285180-32bxx94u	54	11	codon	codon	NNP
cord-285180-32bxx94u	54	12	and	and	CC
cord-285180-32bxx94u	54	13	the	the	DT
cord-285180-32bxx94u	54	14	fifth	fifth	JJ
cord-285180-32bxx94u	54	15	codon	codon	NN
cord-285180-32bxx94u	54	16	of	of	IN
cord-285180-32bxx94u	54	17	the	the	DT
cord-285180-32bxx94u	54	18	NS7	NS7	NNP
cord-285180-32bxx94u	54	19	ORF	ORF	NNP
cord-285180-32bxx94u	54	20	were	be	VBD
cord-285180-32bxx94u	54	21	modified	modify	VBN
cord-285180-32bxx94u	54	22	to	to	TO
cord-285180-32bxx94u	54	23	disrupt	disrupt	VB
cord-285180-32bxx94u	54	24	its	-PRON-	PRP$
cord-285180-32bxx94u	54	25	expression	expression	NN
cord-285180-32bxx94u	54	26	by	by	IN
cord-285180-32bxx94u	54	27	pBud	pBud	NNP
cord-285180-32bxx94u	54	28	-	-	HYPH
cord-285180-32bxx94u	54	29	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	54	30	-	-	HYPH
cord-285180-32bxx94u	54	31	N.	n.	NN
cord-285180-32bxx94u	55	1	To	to	TO
cord-285180-32bxx94u	55	2	accomplish	accomplish	VB
cord-285180-32bxx94u	55	3	this	this	DT
cord-285180-32bxx94u	55	4	,	,	,
cord-285180-32bxx94u	55	5	overlapping	overlap	VBG
cord-285180-32bxx94u	55	6	PCR	PCR	NNP
cord-285180-32bxx94u	55	7	was	be	VBD
cord-285180-32bxx94u	55	8	conducted	conduct	VBN
cord-285180-32bxx94u	55	9	to	to	TO
cord-285180-32bxx94u	55	10	simultaneously	simultaneously	RB
cord-285180-32bxx94u	55	11	change	change	VB
cord-285180-32bxx94u	55	12	the	the	DT
cord-285180-32bxx94u	55	13	ATG	ATG	NNP
cord-285180-32bxx94u	55	14	start	start	NN
cord-285180-32bxx94u	55	15	codon	codon	NN
cord-285180-32bxx94u	55	16	and	and	CC
cord-285180-32bxx94u	55	17	the	the	DT
cord-285180-32bxx94u	55	18	fifth	fifth	JJ
cord-285180-32bxx94u	55	19	codon	codon	NN
cord-285180-32bxx94u	55	20	of	of	IN
cord-285180-32bxx94u	55	21	the	the	DT
cord-285180-32bxx94u	55	22	NS7	NS7	NNP
cord-285180-32bxx94u	55	23	gene	gene	NN
cord-285180-32bxx94u	55	24	to	to	IN
cord-285180-32bxx94u	55	25	TTA	TTA	NNP
cord-285180-32bxx94u	55	26	and	and	CC
cord-285180-32bxx94u	55	27	TAA	TAA	NNP
cord-285180-32bxx94u	55	28	at	at	IN
cord-285180-32bxx94u	55	29	genomic	genomic	JJ
cord-285180-32bxx94u	55	30	nucleotide	nucleotide	JJ
cord-285180-32bxx94u	55	31	positions	position	NNS
cord-285180-32bxx94u	55	32	24,096	24,096	CD
cord-285180-32bxx94u	55	33	-	-	SYM
cord-285180-32bxx94u	55	34	24,098	24,098	CD
cord-285180-32bxx94u	55	35	and	and	CC
cord-285180-32bxx94u	55	36	24,108	24,108	CD
cord-285180-32bxx94u	55	37	-	-	HYPH
cord-285180-32bxx94u	55	38	24,110	24,110	CD
cord-285180-32bxx94u	55	39	,	,	,
cord-285180-32bxx94u	55	40	respectively	respectively	RB
cord-285180-32bxx94u	55	41	,	,	,
cord-285180-32bxx94u	55	42	using	use	VBG
cord-285180-32bxx94u	55	43	pBud	pbud	JJ
cord-285180-32bxx94u	55	44	-	-	HYPH
cord-285180-32bxx94u	55	45	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	55	46	-	-	HYPH
cord-285180-32bxx94u	55	47	N	N	NNP
cord-285180-32bxx94u	55	48	as	as	IN
cord-285180-32bxx94u	55	49	a	a	DT
cord-285180-32bxx94u	55	50	template	template	NN
cord-285180-32bxx94u	55	51	with	with	IN
cord-285180-32bxx94u	55	52	the	the	DT
cord-285180-32bxx94u	55	53	following	follow	VBG
cord-285180-32bxx94u	55	54	primers	primer	NNS
cord-285180-32bxx94u	55	55	for	for	IN
cord-285180-32bxx94u	55	56	the	the	DT
cord-285180-32bxx94u	55	57	T24097C	T24097C	NNP
cord-285180-32bxx94u	55	58	/	/	SYM
cord-285180-32bxx94u	55	59	T24109A	t24109a	CD
cord-285180-32bxx94u	55	60	mutation	mutation	NN
cord-285180-32bxx94u	55	61	:	:	:
cord-285180-32bxx94u	56	1	NS7-KO	ns7-ko	NN
cord-285180-32bxx94u	56	2	-	-	HYPH
cord-285180-32bxx94u	56	3	Fwd	Fwd	NNP
cord-285180-32bxx94u	56	4	(	(	-LRB-
cord-285180-32bxx94u	56	5	5	5	CD
cord-285180-32bxx94u	56	6	-GGCAAcGGAGTTCCGCTaAACTCCGCCATC-3	-GGCAAcGGAGTTCCGCTaAACTCCGCCATC-3	NFP
cord-285180-32bxx94u	56	7	)	)	-RRB-
cord-285180-32bxx94u	56	8	and	and	CC
cord-285180-32bxx94u	56	9	NS7-KO	ns7-ko	NN
cord-285180-32bxx94u	56	10	-	-	HYPH
cord-285180-32bxx94u	56	11	Rev	Rev	NNP
cord-285180-32bxx94u	56	12	(	(	-LRB-
cord-285180-32bxx94u	56	13	5	5	CD
cord-285180-32bxx94u	56	14	-GATGGCGGAGTTtAGCGGAACTCCgTTGCC-3	-GATGGCGGAGTTtAGCGGAACTCCgTTGCC-3	NFP
cord-285180-32bxx94u	56	15	)	)	-RRB-
cord-285180-32bxx94u	56	16	,	,	,
cord-285180-32bxx94u	56	17	where	where	WRB
cord-285180-32bxx94u	56	18	lowercase	lowercase	NN
cord-285180-32bxx94u	56	19	letters	letter	NNS
cord-285180-32bxx94u	56	20	indicate	indicate	VBP
cord-285180-32bxx94u	56	21	the	the	DT
cord-285180-32bxx94u	56	22	mutated	mutate	VBN
cord-285180-32bxx94u	56	23	nucleotides	nucleotide	NNS
cord-285180-32bxx94u	56	24	.	.	.
cord-285180-32bxx94u	57	1	Both	both	DT
cord-285180-32bxx94u	57	2	mutations	mutation	NNS
cord-285180-32bxx94u	57	3	were	be	VBD
cord-285180-32bxx94u	57	4	translationally	translationally	RB
cord-285180-32bxx94u	57	5	silent	silent	JJ
cord-285180-32bxx94u	57	6	with	with	IN
cord-285180-32bxx94u	57	7	respect	respect	NN
cord-285180-32bxx94u	57	8	to	to	IN
cord-285180-32bxx94u	57	9	the	the	DT
cord-285180-32bxx94u	57	10	ORF	ORF	NNP
cord-285180-32bxx94u	57	11	encoding	encode	VBG
cord-285180-32bxx94u	57	12	the	the	DT
cord-285180-32bxx94u	57	13	N	n	CD
cord-285180-32bxx94u	57	14	protein	protein	NN
cord-285180-32bxx94u	57	15	,	,	,
cord-285180-32bxx94u	57	16	and	and	CC
cord-285180-32bxx94u	57	17	the	the	DT
cord-285180-32bxx94u	57	18	resulting	result	VBG
cord-285180-32bxx94u	57	19	plasmid	plasmid	JJ
cord-285180-32bxx94u	57	20	pBud	pBud	NNP
cord-285180-32bxx94u	57	21	-	-	HYPH
cord-285180-32bxx94u	57	22	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	57	23	-	-	HYPH
cord-285180-32bxx94u	57	24	N	N	NNP
cord-285180-32bxx94u	57	25	w	w	NNP
cord-285180-32bxx94u	57	26	/	/	SYM
cord-285180-32bxx94u	57	27	oNS7	oNS7	NNP
cord-285180-32bxx94u	57	28	was	be	VBD
cord-285180-32bxx94u	57	29	verified	verify	VBN
cord-285180-32bxx94u	57	30	by	by	IN
cord-285180-32bxx94u	57	31	nucleotide	nucleotide	JJ
cord-285180-32bxx94u	57	32	sequencing	sequencing	NN
cord-285180-32bxx94u	57	33	.	.	.
cord-285180-32bxx94u	58	1	A	a	DT
cord-285180-32bxx94u	58	2	fragment	fragment	NN
cord-285180-32bxx94u	58	3	of	of	IN
cord-285180-32bxx94u	58	4	PDCoV	pdcov	NN
cord-285180-32bxx94u	58	5	N	N	NNP
cord-285180-32bxx94u	58	6	w	w	NNP
cord-285180-32bxx94u	58	7	/	/	SYM
cord-285180-32bxx94u	58	8	oNS7	oNS7	NNP
cord-285180-32bxx94u	58	9	cDNA	cDNA	NNP
cord-285180-32bxx94u	58	10	that	that	WDT
cord-285180-32bxx94u	58	11	was	be	VBD
cord-285180-32bxx94u	58	12	prepared	prepare	VBN
cord-285180-32bxx94u	58	13	from	from	IN
cord-285180-32bxx94u	58	14	pBud	pbud	JJ
cord-285180-32bxx94u	58	15	-	-	HYPH
cord-285180-32bxx94u	58	16	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	58	17	-	-	HYPH
cord-285180-32bxx94u	58	18	N	N	NNP
cord-285180-32bxx94u	58	19	was	be	VBD
cord-285180-32bxx94u	58	20	then	then	RB
cord-285180-32bxx94u	58	21	subcloned	subclone	VBN
cord-285180-32bxx94u	58	22	into	into	IN
cord-285180-32bxx94u	58	23	the	the	DT
cord-285180-32bxx94u	58	24	pFB	pFB	NNP
cord-285180-32bxx94u	58	25	-	-	HYPH
cord-285180-32bxx94u	58	26	Neo	Neo	NNP
cord-285180-32bxx94u	58	27	retroviral	retroviral	NN
cord-285180-32bxx94u	58	28	vector	vector	NN
cord-285180-32bxx94u	58	29	(	(	-LRB-
cord-285180-32bxx94u	58	30	Stratagene	Stratagene	NNP
cord-285180-32bxx94u	58	31	,	,	,
cord-285180-32bxx94u	58	32	La	La	NNP
cord-285180-32bxx94u	58	33	Jolla	Jolla	NNP
cord-285180-32bxx94u	58	34	,	,	,
cord-285180-32bxx94u	58	35	CA	CA	NNP
cord-285180-32bxx94u	58	36	)	)	-RRB-
cord-285180-32bxx94u	58	37	using	use	VBG
cord-285180-32bxx94u	58	38	the	the	DT
cord-285180-32bxx94u	58	39	SalI	SalI	NNP
cord-285180-32bxx94u	58	40	and	and	CC
cord-285180-32bxx94u	58	41	EcoRI	ecori	NN
cord-285180-32bxx94u	58	42	restriction	restriction	NN
cord-285180-32bxx94u	58	43	sites	site	NNS
cord-285180-32bxx94u	58	44	to	to	TO
cord-285180-32bxx94u	58	45	construct	construct	VB
cord-285180-32bxx94u	58	46	the	the	DT
cord-285180-32bxx94u	58	47	PDCoV	pdcov	NN
cord-285180-32bxx94u	58	48	N	n	CD
cord-285180-32bxx94u	58	49	gene	gene	NN
cord-285180-32bxx94u	58	50	expression	expression	NN
cord-285180-32bxx94u	58	51	plasmid	plasmid	NN
cord-285180-32bxx94u	58	52	pFB	pFB	NNP
cord-285180-32bxx94u	58	53	-	-	HYPH
cord-285180-32bxx94u	58	54	Neo	Neo	NNP
cord-285180-32bxx94u	58	55	-	-	HYPH
cord-285180-32bxx94u	58	56	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	58	57	-	-	HYPH
cord-285180-32bxx94u	58	58	N	N	NNP
cord-285180-32bxx94u	58	59	-	-	HYPH
cord-285180-32bxx94u	58	60	myc/	myc/	NNP
cord-285180-32bxx94u	59	1	His	-PRON-	PRP$
cord-285180-32bxx94u	59	2	that	that	WDT
cord-285180-32bxx94u	59	3	produces	produce	VBZ
cord-285180-32bxx94u	59	4	recombinant	recombinant	JJ
cord-285180-32bxx94u	59	5	N	n	CD
cord-285180-32bxx94u	59	6	protein	protein	NN
cord-285180-32bxx94u	59	7	.	.	.
cord-285180-32bxx94u	60	1	The	the	DT
cord-285180-32bxx94u	60	2	retrovirus	retrovirus	NN
cord-285180-32bxx94u	60	3	gene	gene	NN
cord-285180-32bxx94u	60	4	transfer	transfer	NN
cord-285180-32bxx94u	60	5	system	system	NN
cord-285180-32bxx94u	60	6	(	(	-LRB-
cord-285180-32bxx94u	60	7	Stratagene	Stratagene	NNP
cord-285180-32bxx94u	60	8	)	)	-RRB-
cord-285180-32bxx94u	60	9	was	be	VBD
cord-285180-32bxx94u	60	10	used	use	VBN
cord-285180-32bxx94u	60	11	to	to	TO
cord-285180-32bxx94u	60	12	generate	generate	VB
cord-285180-32bxx94u	60	13	cell	cell	NN
cord-285180-32bxx94u	60	14	lines	line	NNS
cord-285180-32bxx94u	60	15	constitutively	constitutively	RB
cord-285180-32bxx94u	60	16	expressing	express	VBG
cord-285180-32bxx94u	60	17	the	the	DT
cord-285180-32bxx94u	60	18	recombinant	recombinant	JJ
cord-285180-32bxx94u	60	19	PDCoV	pdcov	NN
cord-285180-32bxx94u	60	20	N	n	CD
cord-285180-32bxx94u	60	21	gene	gene	NN
cord-285180-32bxx94u	60	22	or	or	CC
cord-285180-32bxx94u	60	23	an	an	DT
cord-285180-32bxx94u	60	24	empty	empty	JJ
cord-285180-32bxx94u	60	25	vector	vector	NN
cord-285180-32bxx94u	60	26	only	only	RB
cord-285180-32bxx94u	60	27	as	as	IN
cord-285180-32bxx94u	60	28	described	describe	VBN
cord-285180-32bxx94u	60	29	elsewhere	elsewhere	RB
cord-285180-32bxx94u	60	30	Nam	Nam	NNP
cord-285180-32bxx94u	60	31	and	and	CC
cord-285180-32bxx94u	60	32	Lee	Lee	NNP
cord-285180-32bxx94u	60	33	,	,	,
cord-285180-32bxx94u	60	34	2010	2010	CD
cord-285180-32bxx94u	60	35	;	;	.
cord-285180-32bxx94u	61	1	Oh	oh	UH
cord-285180-32bxx94u	61	2	and	and	CC
cord-285180-32bxx94u	61	3	Lee	Lee	NNP
cord-285180-32bxx94u	61	4	,	,	,
cord-285180-32bxx94u	61	5	2012	2012	CD
cord-285180-32bxx94u	61	6	)	)	-RRB-
cord-285180-32bxx94u	61	7	.	.	.
cord-285180-32bxx94u	62	1	Antibioticresistant	antibioticresistant	JJ
cord-285180-32bxx94u	62	2	continuous	continuous	JJ
cord-285180-32bxx94u	62	3	cell	cell	NN
cord-285180-32bxx94u	62	4	clones	clone	NNS
cord-285180-32bxx94u	62	5	were	be	VBD
cord-285180-32bxx94u	62	6	analyzed	analyze	VBN
cord-285180-32bxx94u	62	7	by	by	IN
cord-285180-32bxx94u	62	8	RT	RT	NNP
cord-285180-32bxx94u	62	9	-	-	HYPH
cord-285180-32bxx94u	62	10	PCR	PCR	NNP
cord-285180-32bxx94u	62	11	to	to	TO
cord-285180-32bxx94u	62	12	determine	determine	VB
cord-285180-32bxx94u	62	13	the	the	DT
cord-285180-32bxx94u	62	14	presence	presence	NN
cord-285180-32bxx94u	62	15	of	of	IN
cord-285180-32bxx94u	62	16	the	the	DT
cord-285180-32bxx94u	62	17	full	full	JJ
cord-285180-32bxx94u	62	18	-	-	HYPH
cord-285180-32bxx94u	62	19	length	length	NN
cord-285180-32bxx94u	62	20	N	n	CD
cord-285180-32bxx94u	62	21	gene	gene	NN
cord-285180-32bxx94u	62	22	,	,	,
cord-285180-32bxx94u	62	23	and	and	CC
cord-285180-32bxx94u	62	24	the	the	DT
cord-285180-32bxx94u	62	25	positive	positive	JJ
cord-285180-32bxx94u	62	26	clones	clone	NNS
cord-285180-32bxx94u	62	27	(	(	-LRB-
cord-285180-32bxx94u	62	28	PK	pk	NN
cord-285180-32bxx94u	62	29	-	-	HYPH
cord-285180-32bxx94u	62	30	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	62	31	-	-	HYPH
cord-285180-32bxx94u	62	32	N	N	NNP
cord-285180-32bxx94u	62	33	and	and	CC
cord-285180-32bxx94u	62	34	PK	PK	NNP
cord-285180-32bxx94u	62	35	-	-	HYPH
cord-285180-32bxx94u	62	36	Neo	Neo	NNP
cord-285180-32bxx94u	62	37	)	)	-RRB-
cord-285180-32bxx94u	62	38	were	be	VBD
cord-285180-32bxx94u	62	39	amplified	amplify	VBN
cord-285180-32bxx94u	62	40	for	for	IN
cord-285180-32bxx94u	62	41	subsequent	subsequent	JJ
cord-285180-32bxx94u	62	42	experiments	experiment	NNS
cord-285180-32bxx94u	62	43	.	.	.
cord-285180-32bxx94u	63	1	PK	PK	NNP
cord-285180-32bxx94u	63	2	-	-	HYPH
cord-285180-32bxx94u	63	3	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	63	4	-	-	HYPH
cord-285180-32bxx94u	63	5	N	n	CD
cord-285180-32bxx94u	63	6	cells	cell	NNS
cord-285180-32bxx94u	63	7	were	be	VBD
cord-285180-32bxx94u	63	8	grown	grow	VBN
cord-285180-32bxx94u	63	9	on	on	IN
cord-285180-32bxx94u	63	10	microscope	microscope	NN
cord-285180-32bxx94u	63	11	coverslips	coverslip	NNS
cord-285180-32bxx94u	63	12	placed	place	VBN
cord-285180-32bxx94u	63	13	in	in	IN
cord-285180-32bxx94u	63	14	6-well	6-well	CD
cord-285180-32bxx94u	63	15	tissue	tissue	NN
cord-285180-32bxx94u	63	16	culture	culture	NN
cord-285180-32bxx94u	63	17	plates	plate	NNS
cord-285180-32bxx94u	63	18	.	.	.
cord-285180-32bxx94u	64	1	At	at	IN
cord-285180-32bxx94u	64	2	48	48	CD
cord-285180-32bxx94u	64	3	h	h	NN
cord-285180-32bxx94u	64	4	post	post	NN
cord-285180-32bxx94u	64	5	-	-	JJ
cord-285180-32bxx94u	64	6	seeding	seeding	JJ
cord-285180-32bxx94u	64	7	,	,	,
cord-285180-32bxx94u	64	8	the	the	DT
cord-285180-32bxx94u	64	9	cells	cell	NNS
cord-285180-32bxx94u	64	10	were	be	VBD
cord-285180-32bxx94u	64	11	fixed	fix	VBN
cord-285180-32bxx94u	64	12	with	with	IN
cord-285180-32bxx94u	64	13	4	4	CD
cord-285180-32bxx94u	64	14	%	%	NN
cord-285180-32bxx94u	64	15	paraformaldehyde	paraformaldehyde	NNP
cord-285180-32bxx94u	64	16	for	for	IN
cord-285180-32bxx94u	64	17	10	10	CD
cord-285180-32bxx94u	64	18	min	min	NN
cord-285180-32bxx94u	64	19	at	at	IN
cord-285180-32bxx94u	64	20	room	room	NN
cord-285180-32bxx94u	64	21	temperature	temperature	NN
cord-285180-32bxx94u	64	22	(	(	-LRB-
cord-285180-32bxx94u	64	23	RT	RT	NNP
cord-285180-32bxx94u	64	24	)	)	-RRB-
cord-285180-32bxx94u	64	25	and	and	CC
cord-285180-32bxx94u	64	26	permeabilized	permeabilize	VBN
cord-285180-32bxx94u	64	27	with	with	IN
cord-285180-32bxx94u	64	28	0.2	0.2	CD
cord-285180-32bxx94u	64	29	%	%	NN
cord-285180-32bxx94u	64	30	Triton	Triton	NNP
cord-285180-32bxx94u	64	31	X-100	x-100	NN
cord-285180-32bxx94u	64	32	in	in	IN
cord-285180-32bxx94u	64	33	PBS	PBS	NNP
cord-285180-32bxx94u	64	34	at	at	IN
cord-285180-32bxx94u	64	35	RT	RT	NNP
cord-285180-32bxx94u	64	36	for	for	IN
cord-285180-32bxx94u	64	37	10	10	CD
cord-285180-32bxx94u	64	38	min	min	NN
cord-285180-32bxx94u	64	39	.	.	.
cord-285180-32bxx94u	65	1	The	the	DT
cord-285180-32bxx94u	65	2	cells	cell	NNS
cord-285180-32bxx94u	65	3	were	be	VBD
cord-285180-32bxx94u	65	4	blocked	block	VBN
cord-285180-32bxx94u	65	5	using	use	VBG
cord-285180-32bxx94u	65	6	1	1	CD
cord-285180-32bxx94u	65	7	%	%	NN
cord-285180-32bxx94u	65	8	bovine	bovine	JJ
cord-285180-32bxx94u	65	9	serum	serum	NN
cord-285180-32bxx94u	65	10	albumin	albumin	NN
cord-285180-32bxx94u	65	11	(	(	-LRB-
cord-285180-32bxx94u	65	12	BSA	BSA	NNP
cord-285180-32bxx94u	65	13	)	)	-RRB-
cord-285180-32bxx94u	65	14	in	in	IN
cord-285180-32bxx94u	65	15	PBS	PBS	NNP
cord-285180-32bxx94u	65	16	for	for	IN
cord-285180-32bxx94u	65	17	30	30	CD
cord-285180-32bxx94u	65	18	min	min	NN
cord-285180-32bxx94u	65	19	at	at	IN
cord-285180-32bxx94u	65	20	RT	RT	NNP
cord-285180-32bxx94u	65	21	and	and	CC
cord-285180-32bxx94u	65	22	then	then	RB
cord-285180-32bxx94u	65	23	incubated	incubate	VBD
cord-285180-32bxx94u	65	24	with	with	IN
cord-285180-32bxx94u	65	25	an	an	DT
cord-285180-32bxx94u	65	26	anti	anti	JJ
cord-285180-32bxx94u	65	27	-	-	JJ
cord-285180-32bxx94u	65	28	His	-PRON-	PRP$
cord-285180-32bxx94u	65	29	tag	tag	NN
cord-285180-32bxx94u	65	30	or	or	CC
cord-285180-32bxx94u	65	31	anti	anti	JJ
cord-285180-32bxx94u	65	32	-	-	JJ
cord-285180-32bxx94u	65	33	myc	myc	JJ
cord-285180-32bxx94u	65	34	antibody	antibody	NN
cord-285180-32bxx94u	65	35	for	for	IN
cord-285180-32bxx94u	65	36	2	2	CD
cord-285180-32bxx94u	65	37	h.	h.	NN
cord-285180-32bxx94u	65	38	After	after	IN
cord-285180-32bxx94u	65	39	washing	washing	NN
cord-285180-32bxx94u	65	40	5	5	CD
cord-285180-32bxx94u	65	41	times	time	NNS
cord-285180-32bxx94u	65	42	in	in	IN
cord-285180-32bxx94u	65	43	PBS	PBS	NNP
cord-285180-32bxx94u	65	44	,	,	,
cord-285180-32bxx94u	65	45	the	the	DT
cord-285180-32bxx94u	65	46	cells	cell	NNS
cord-285180-32bxx94u	65	47	were	be	VBD
cord-285180-32bxx94u	65	48	incubated	incubate	VBN
cord-285180-32bxx94u	65	49	for	for	IN
cord-285180-32bxx94u	65	50	1	1	CD
cord-285180-32bxx94u	65	51	h	h	NN
cord-285180-32bxx94u	65	52	at	at	IN
cord-285180-32bxx94u	65	53	RT	RT	NNP
cord-285180-32bxx94u	65	54	with	with	IN
cord-285180-32bxx94u	65	55	a	a	DT
cord-285180-32bxx94u	65	56	goat	goat	NN
cord-285180-32bxx94u	65	57	anti	anti	JJ
cord-285180-32bxx94u	65	58	-	-	JJ
cord-285180-32bxx94u	65	59	mouse	mouse	JJ
cord-285180-32bxx94u	65	60	secondary	secondary	JJ
cord-285180-32bxx94u	65	61	antibody	antibody	NN
cord-285180-32bxx94u	65	62	conjugated	conjugate	VBN
cord-285180-32bxx94u	65	63	with	with	IN
cord-285180-32bxx94u	65	64	Alexa	Alexa	NNP
cord-285180-32bxx94u	65	65	Fluor	Fluor	NNP
cord-285180-32bxx94u	65	66	488	488	CD
cord-285180-32bxx94u	66	1	(	(	-LRB-
cord-285180-32bxx94u	66	2	Molecular	Molecular	NNP
cord-285180-32bxx94u	66	3	Probes	Probes	NNPS
cord-285180-32bxx94u	66	4	,	,	,
cord-285180-32bxx94u	66	5	Carlsbad	Carlsbad	NNP
cord-285180-32bxx94u	66	6	,	,	,
cord-285180-32bxx94u	66	7	CA	CA	NNP
cord-285180-32bxx94u	66	8	)	)	-RRB-
cord-285180-32bxx94u	66	9	.	.	.
cord-285180-32bxx94u	67	1	The	the	DT
cord-285180-32bxx94u	67	2	cells	cell	NNS
cord-285180-32bxx94u	67	3	were	be	VBD
cord-285180-32bxx94u	67	4	finally	finally	RB
cord-285180-32bxx94u	67	5	counterstained	counterstaine	VBN
cord-285180-32bxx94u	67	6	with	with	IN
cord-285180-32bxx94u	67	7	4	4	CD
cord-285180-32bxx94u	67	8	,	,	,
cord-285180-32bxx94u	67	9	6-diamidino-2phenylindole	6-diamidino-2phenylindole	CD
cord-285180-32bxx94u	67	10	(	(	-LRB-
cord-285180-32bxx94u	67	11	DAPI	DAPI	NNP
cord-285180-32bxx94u	67	12	;	;	:
cord-285180-32bxx94u	67	13	Sigma	Sigma	NNP
cord-285180-32bxx94u	67	14	,	,	,
cord-285180-32bxx94u	67	15	St.	St.	NNP
cord-285180-32bxx94u	67	16	Louis	Louis	NNP
cord-285180-32bxx94u	67	17	,	,	,
cord-285180-32bxx94u	67	18	MO	MO	NNP
cord-285180-32bxx94u	67	19	)	)	-RRB-
cord-285180-32bxx94u	67	20	,	,	,
cord-285180-32bxx94u	67	21	and	and	CC
cord-285180-32bxx94u	67	22	the	the	DT
cord-285180-32bxx94u	67	23	cell	cell	NN
cord-285180-32bxx94u	67	24	staining	staining	NN
cord-285180-32bxx94u	67	25	was	be	VBD
cord-285180-32bxx94u	67	26	visualized	visualize	VBN
cord-285180-32bxx94u	67	27	by	by	IN
cord-285180-32bxx94u	67	28	the	the	DT
cord-285180-32bxx94u	67	29	fluorescence	fluorescence	NN
cord-285180-32bxx94u	67	30	Leica	Leica	NNP
cord-285180-32bxx94u	67	31	DM	DM	NNP
cord-285180-32bxx94u	67	32	IL	IL	NNP
cord-285180-32bxx94u	67	33	LED	led	NN
cord-285180-32bxx94u	67	34	microscope	microscope	NN
cord-285180-32bxx94u	67	35	(	(	-LRB-
cord-285180-32bxx94u	67	36	Leica	Leica	NNP
cord-285180-32bxx94u	67	37	,	,	,
cord-285180-32bxx94u	67	38	Wetzlar	Wetzlar	NNP
cord-285180-32bxx94u	67	39	,	,	,
cord-285180-32bxx94u	67	40	Germany	Germany	NNP
cord-285180-32bxx94u	67	41	)	)	-RRB-
cord-285180-32bxx94u	67	42	or	or	CC
cord-285180-32bxx94u	67	43	a	a	DT
cord-285180-32bxx94u	67	44	Confocal	Confocal	NNP
cord-285180-32bxx94u	67	45	Laser	Laser	NNP
cord-285180-32bxx94u	67	46	Scanning	scanning	NN
cord-285180-32bxx94u	67	47	microscope	microscope	NN
cord-285180-32bxx94u	67	48	(	(	-LRB-
cord-285180-32bxx94u	67	49	Carl	Carl	NNP
cord-285180-32bxx94u	67	50	Zeiss	Zeiss	NNP
cord-285180-32bxx94u	67	51	,	,	,
cord-285180-32bxx94u	67	52	Gattingen	Gattingen	NNP
cord-285180-32bxx94u	67	53	,	,	,
cord-285180-32bxx94u	67	54	Germany	Germany	NNP
cord-285180-32bxx94u	67	55	)	)	-RRB-
cord-285180-32bxx94u	67	56	.	.	.
cord-285180-32bxx94u	68	1	The	the	DT
cord-285180-32bxx94u	68	2	N	n	CD
cord-285180-32bxx94u	68	3	expression	expression	NN
cord-285180-32bxx94u	68	4	in	in	IN
cord-285180-32bxx94u	68	5	PK	PK	NNP
cord-285180-32bxx94u	68	6	-	-	HYPH
cord-285180-32bxx94u	68	7	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	68	8	-	-	HYPH
cord-285180-32bxx94u	68	9	N	n	CD
cord-285180-32bxx94u	68	10	cells	cell	NNS
cord-285180-32bxx94u	68	11	was	be	VBD
cord-285180-32bxx94u	68	12	analyzed	analyze	VBN
cord-285180-32bxx94u	68	13	by	by	IN
cord-285180-32bxx94u	68	14	flow	flow	NN
cord-285180-32bxx94u	68	15	cytometry	cytometry	NN
cord-285180-32bxx94u	68	16	.	.	.
cord-285180-32bxx94u	69	1	The	the	DT
cord-285180-32bxx94u	69	2	cells	cell	NNS
cord-285180-32bxx94u	69	3	were	be	VBD
cord-285180-32bxx94u	69	4	trypsinized	trypsinize	VBN
cord-285180-32bxx94u	69	5	at	at	IN
cord-285180-32bxx94u	69	6	48	48	CD
cord-285180-32bxx94u	69	7	h	h	NN
cord-285180-32bxx94u	69	8	post	post	NN
cord-285180-32bxx94u	69	9	-	-	JJ
cord-285180-32bxx94u	69	10	seeding	seeding	JJ
cord-285180-32bxx94u	69	11	and	and	CC
cord-285180-32bxx94u	69	12	centrifuged	centrifuge	VBN
cord-285180-32bxx94u	69	13	at	at	IN
cord-285180-32bxx94u	69	14	250	250	CD
cord-285180-32bxx94u	69	15	×	×	NN
cord-285180-32bxx94u	69	16	g	g	NN
cord-285180-32bxx94u	69	17	(	(	-LRB-
cord-285180-32bxx94u	69	18	Hanil	Hanil	NNP
cord-285180-32bxx94u	69	19	Centrifuge	Centrifuge	NNP
cord-285180-32bxx94u	69	20	FLETA	FLETA	NNP
cord-285180-32bxx94u	69	21	5	5	CD
cord-285180-32bxx94u	69	22	)	)	-RRB-
cord-285180-32bxx94u	69	23	for	for	IN
cord-285180-32bxx94u	69	24	5	5	CD
cord-285180-32bxx94u	69	25	min	min	NN
cord-285180-32bxx94u	69	26	.	.	.
cord-285180-32bxx94u	70	1	The	the	DT
cord-285180-32bxx94u	70	2	cell	cell	NN
cord-285180-32bxx94u	70	3	pellet	pellet	NN
cord-285180-32bxx94u	70	4	was	be	VBD
cord-285180-32bxx94u	70	5	washed	wash	VBN
cord-285180-32bxx94u	70	6	with	with	IN
cord-285180-32bxx94u	70	7	cold	cold	JJ
cord-285180-32bxx94u	70	8	washing	washing	NN
cord-285180-32bxx94u	70	9	buffer	buffer	NN
cord-285180-32bxx94u	70	10	(	(	-LRB-
cord-285180-32bxx94u	70	11	1	1	CD
cord-285180-32bxx94u	70	12	%	%	NN
cord-285180-32bxx94u	70	13	BSA	BSA	NNP
cord-285180-32bxx94u	70	14	and	and	CC
cord-285180-32bxx94u	70	15	0.1	0.1	CD
cord-285180-32bxx94u	70	16	%	%	NN
cord-285180-32bxx94u	70	17	sodium	sodium	NN
cord-285180-32bxx94u	70	18	azide	azide	NN
cord-285180-32bxx94u	70	19	in	in	IN
cord-285180-32bxx94u	70	20	PBS	PBS	NNP
cord-285180-32bxx94u	70	21	)	)	-RRB-
cord-285180-32bxx94u	70	22	,	,	,
cord-285180-32bxx94u	70	23	and	and	CC
cord-285180-32bxx94u	70	24	10	10	CD
cord-285180-32bxx94u	70	25	6	6	CD
cord-285180-32bxx94u	70	26	cells	cell	NNS
cord-285180-32bxx94u	70	27	were	be	VBD
cord-285180-32bxx94u	70	28	resuspended	resuspend	VBN
cord-285180-32bxx94u	70	29	in	in	IN
cord-285180-32bxx94u	70	30	1	1	CD
cord-285180-32bxx94u	70	31	%	%	NN
cord-285180-32bxx94u	70	32	formaldehyde	formaldehyde	NN
cord-285180-32bxx94u	70	33	solution	solution	NN
cord-285180-32bxx94u	70	34	in	in	IN
cord-285180-32bxx94u	70	35	cold	cold	JJ
cord-285180-32bxx94u	70	36	wash	wash	NN
cord-285180-32bxx94u	70	37	buffer	buffer	NN
cord-285180-32bxx94u	70	38	for	for	IN
cord-285180-32bxx94u	70	39	fixation	fixation	NN
cord-285180-32bxx94u	70	40	at	at	IN
cord-285180-32bxx94u	70	41	4	4	CD
cord-285180-32bxx94u	70	42	•	•	NN
cord-285180-32bxx94u	70	43	C	c	NN
cord-285180-32bxx94u	70	44	in	in	IN
cord-285180-32bxx94u	70	45	the	the	DT
cord-285180-32bxx94u	70	46	dark	dark	NN
cord-285180-32bxx94u	70	47	for	for	IN
cord-285180-32bxx94u	70	48	30	30	CD
cord-285180-32bxx94u	70	49	min	min	NN
cord-285180-32bxx94u	70	50	followed	follow	VBN
cord-285180-32bxx94u	70	51	by	by	IN
cord-285180-32bxx94u	70	52	centrifugation	centrifugation	NN
cord-285180-32bxx94u	70	53	and	and	CC
cord-285180-32bxx94u	70	54	incubation	incubation	NN
cord-285180-32bxx94u	70	55	of	of	IN
cord-285180-32bxx94u	70	56	the	the	DT
cord-285180-32bxx94u	70	57	pellet	pellet	NN
cord-285180-32bxx94u	70	58	in	in	IN
cord-285180-32bxx94u	70	59	0.2	0.2	CD
cord-285180-32bxx94u	70	60	%	%	NN
cord-285180-32bxx94u	70	61	Triton	Triton	NNP
cord-285180-32bxx94u	70	62	X-100	x-100	NN
cord-285180-32bxx94u	70	63	in	in	IN
cord-285180-32bxx94u	70	64	PBS	PBS	NNP
cord-285180-32bxx94u	70	65	at	at	IN
cord-285180-32bxx94u	70	66	37	37	CD
cord-285180-32bxx94u	71	1	•	•	NNP
cord-285180-32bxx94u	71	2	C	C	NNP
cord-285180-32bxx94u	71	3	for	for	IN
cord-285180-32bxx94u	71	4	15	15	CD
cord-285180-32bxx94u	71	5	min	min	NN
cord-285180-32bxx94u	71	6	for	for	IN
cord-285180-32bxx94u	71	7	permeabilization	permeabilization	NN
cord-285180-32bxx94u	71	8	.	.	.
cord-285180-32bxx94u	72	1	After	after	IN
cord-285180-32bxx94u	72	2	centrifugation	centrifugation	NN
cord-285180-32bxx94u	72	3	,	,	,
cord-285180-32bxx94u	72	4	the	the	DT
cord-285180-32bxx94u	72	5	cell	cell	NN
cord-285180-32bxx94u	72	6	pellet	pellet	NN
cord-285180-32bxx94u	72	7	was	be	VBD
cord-285180-32bxx94u	72	8	resuspended	resuspend	VBN
cord-285180-32bxx94u	72	9	in	in	IN
cord-285180-32bxx94u	72	10	a	a	DT
cord-285180-32bxx94u	72	11	solution	solution	NN
cord-285180-32bxx94u	72	12	of	of	IN
cord-285180-32bxx94u	72	13	the	the	DT
cord-285180-32bxx94u	72	14	primary	primary	JJ
cord-285180-32bxx94u	72	15	anti	anti	JJ
cord-285180-32bxx94u	72	16	-	-	JJ
cord-285180-32bxx94u	72	17	His	-PRON-	PRP$
cord-285180-32bxx94u	72	18	tag	tag	NN
cord-285180-32bxx94u	72	19	antibody	antibody	NN
cord-285180-32bxx94u	72	20	or	or	CC
cord-285180-32bxx94u	72	21	normal	normal	JJ
cord-285180-32bxx94u	72	22	mouse	mouse	NN
cord-285180-32bxx94u	72	23	IgG1	igg1	NN
cord-285180-32bxx94u	73	1	(	(	-LRB-
cord-285180-32bxx94u	73	2	Santa	Santa	NNP
cord-285180-32bxx94u	73	3	Cruz	Cruz	NNP
cord-285180-32bxx94u	73	4	Biotechnology	Biotechnology	NNP
cord-285180-32bxx94u	73	5	)	)	-RRB-
cord-285180-32bxx94u	73	6	and	and	CC
cord-285180-32bxx94u	73	7	the	the	DT
cord-285180-32bxx94u	73	8	mixture	mixture	NN
cord-285180-32bxx94u	73	9	was	be	VBD
cord-285180-32bxx94u	73	10	incubated	incubate	VBN
cord-285180-32bxx94u	73	11	at	at	IN
cord-285180-32bxx94u	73	12	4	4	CD
cord-285180-32bxx94u	73	13	•	•	NN
cord-285180-32bxx94u	73	14	C	C	NNP
cord-285180-32bxx94u	73	15	for	for	IN
cord-285180-32bxx94u	73	16	30	30	CD
cord-285180-32bxx94u	73	17	min	min	NN
cord-285180-32bxx94u	73	18	.	.	.
cord-285180-32bxx94u	74	1	The	the	DT
cord-285180-32bxx94u	74	2	cells	cell	NNS
cord-285180-32bxx94u	74	3	were	be	VBD
cord-285180-32bxx94u	74	4	washed	wash	VBN
cord-285180-32bxx94u	74	5	and	and	CC
cord-285180-32bxx94u	74	6	allowed	allow	VBN
cord-285180-32bxx94u	74	7	to	to	TO
cord-285180-32bxx94u	74	8	react	react	VB
cord-285180-32bxx94u	74	9	with	with	IN
cord-285180-32bxx94u	74	10	an	an	DT
cord-285180-32bxx94u	74	11	Alexa	Alexa	NNP
cord-285180-32bxx94u	74	12	Fluor	Fluor	NNP
cord-285180-32bxx94u	74	13	488-conjugated	488-conjugated	CD
cord-285180-32bxx94u	74	14	anti	anti	JJ
cord-285180-32bxx94u	74	15	-	-	JJ
cord-285180-32bxx94u	74	16	mouse	mouse	JJ
cord-285180-32bxx94u	74	17	IgG	igg	NN
cord-285180-32bxx94u	74	18	secondary	secondary	JJ
cord-285180-32bxx94u	74	19	antibody	antibody	NN
cord-285180-32bxx94u	74	20	at	at	IN
cord-285180-32bxx94u	74	21	4	4	CD
cord-285180-32bxx94u	74	22	•	•	NN
cord-285180-32bxx94u	74	23	C	C	NNP
cord-285180-32bxx94u	74	24	for	for	IN
cord-285180-32bxx94u	74	25	30	30	CD
cord-285180-32bxx94u	74	26	min	min	NN
cord-285180-32bxx94u	74	27	in	in	IN
cord-285180-32bxx94u	74	28	the	the	DT
cord-285180-32bxx94u	74	29	dark	dark	NN
cord-285180-32bxx94u	74	30	.	.	.
cord-285180-32bxx94u	75	1	The	the	DT
cord-285180-32bxx94u	75	2	stained	stained	JJ
cord-285180-32bxx94u	75	3	cells	cell	NNS
cord-285180-32bxx94u	75	4	were	be	VBD
cord-285180-32bxx94u	75	5	washed	wash	VBN
cord-285180-32bxx94u	75	6	again	again	RB
cord-285180-32bxx94u	75	7	and	and	CC
cord-285180-32bxx94u	75	8	analyzed	analyze	VBD
cord-285180-32bxx94u	75	9	on	on	IN
cord-285180-32bxx94u	75	10	the	the	DT
cord-285180-32bxx94u	75	11	BD	BD	NNP
cord-285180-32bxx94u	75	12	FACSAria	facsaria	NN
cord-285180-32bxx94u	75	13	III	iii	CD
cord-285180-32bxx94u	75	14	flow	flow	NN
cord-285180-32bxx94u	75	15	cytometer	cytometer	NN
cord-285180-32bxx94u	75	16	(	(	-LRB-
cord-285180-32bxx94u	75	17	BD	BD	NNP
cord-285180-32bxx94u	75	18	Biosciences	Biosciences	NNP
cord-285180-32bxx94u	75	19	,	,	,
cord-285180-32bxx94u	75	20	Belford	Belford	NNP
cord-285180-32bxx94u	75	21	,	,	,
cord-285180-32bxx94u	75	22	MA	MA	NNP
cord-285180-32bxx94u	75	23	)	)	-RRB-
cord-285180-32bxx94u	75	24	.	.	.
cord-285180-32bxx94u	76	1	The	the	DT
cord-285180-32bxx94u	76	2	growth	growth	NN
cord-285180-32bxx94u	76	3	properties	property	NNS
cord-285180-32bxx94u	76	4	of	of	IN
cord-285180-32bxx94u	76	5	cells	cell	NNS
cord-285180-32bxx94u	76	6	expressing	express	VBG
cord-285180-32bxx94u	76	7	PDCoV	pdcov	NN
cord-285180-32bxx94u	76	8	N	n	CD
cord-285180-32bxx94u	76	9	protein	protein	NN
cord-285180-32bxx94u	76	10	and	and	CC
cord-285180-32bxx94u	76	11	control	control	NN
cord-285180-32bxx94u	76	12	cells	cell	NNS
cord-285180-32bxx94u	76	13	were	be	VBD
cord-285180-32bxx94u	76	14	determined	determine	VBN
cord-285180-32bxx94u	76	15	by	by	IN
cord-285180-32bxx94u	76	16	a	a	DT
cord-285180-32bxx94u	76	17	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium	CD
cord-285180-32bxx94u	76	18	bromide	bromide	NN
cord-285180-32bxx94u	76	19	(	(	-LRB-
cord-285180-32bxx94u	76	20	MTT	MTT	NNP
cord-285180-32bxx94u	76	21	)	)	-RRB-
cord-285180-32bxx94u	76	22	assay	assay	NN
cord-285180-32bxx94u	76	23	(	(	-LRB-
cord-285180-32bxx94u	76	24	Sigma	Sigma	NNP
cord-285180-32bxx94u	76	25	)	)	-RRB-
cord-285180-32bxx94u	76	26	detecting	detect	VBG
cord-285180-32bxx94u	76	27	cell	cell	NN
cord-285180-32bxx94u	76	28	viability	viability	NN
cord-285180-32bxx94u	76	29	as	as	IN
cord-285180-32bxx94u	76	30	described	describe	VBN
cord-285180-32bxx94u	76	31	previously	previously	RB
cord-285180-32bxx94u	76	32	(	(	-LRB-
cord-285180-32bxx94u	76	33	Kim	Kim	NNP
cord-285180-32bxx94u	76	34	and	and	CC
cord-285180-32bxx94u	76	35	Lee	Lee	NNP
cord-285180-32bxx94u	76	36	,	,	,
cord-285180-32bxx94u	76	37	2013	2013	CD
cord-285180-32bxx94u	76	38	)	)	-RRB-
cord-285180-32bxx94u	76	39	.	.	.
cord-285180-32bxx94u	77	1	All	all	DT
cord-285180-32bxx94u	77	2	MTT	MTT	NNP
cord-285180-32bxx94u	77	3	assays	assay	NNS
cord-285180-32bxx94u	77	4	were	be	VBD
cord-285180-32bxx94u	77	5	performed	perform	VBN
cord-285180-32bxx94u	77	6	in	in	IN
cord-285180-32bxx94u	77	7	triplicate	triplicate	NN
cord-285180-32bxx94u	77	8	.	.	.
cord-285180-32bxx94u	78	1	Whole	whole	JJ
cord-285180-32bxx94u	78	2	cell	cell	NN
cord-285180-32bxx94u	78	3	lysates	lysate	NNS
cord-285180-32bxx94u	78	4	were	be	VBD
cord-285180-32bxx94u	78	5	prepared	prepare	VBN
cord-285180-32bxx94u	78	6	from	from	IN
cord-285180-32bxx94u	78	7	PK	PK	NNP
cord-285180-32bxx94u	78	8	-	-	HYPH
cord-285180-32bxx94u	78	9	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	78	10	-	-	HYPH
cord-285180-32bxx94u	78	11	N	n	CD
cord-285180-32bxx94u	78	12	cells	cell	NNS
cord-285180-32bxx94u	78	13	grown	grow	VBN
cord-285180-32bxx94u	78	14	at	at	IN
cord-285180-32bxx94u	78	15	5	5	CD
cord-285180-32bxx94u	78	16	×	×	CD
cord-285180-32bxx94u	78	17	10	10	CD
cord-285180-32bxx94u	78	18	5	5	CD
cord-285180-32bxx94u	78	19	cells/	cells/	CD
cord-285180-32bxx94u	79	1	well	well	UH
cord-285180-32bxx94u	79	2	in	in	IN
cord-285180-32bxx94u	79	3	6-well	6-well	CD
cord-285180-32bxx94u	79	4	tissue	tissue	NN
cord-285180-32bxx94u	79	5	culture	culture	NN
cord-285180-32bxx94u	79	6	plates	plate	NNS
cord-285180-32bxx94u	79	7	at	at	IN
cord-285180-32bxx94u	79	8	indicated	indicate	VBN
cord-285180-32bxx94u	79	9	time	time	NN
cord-285180-32bxx94u	79	10	points	point	NNS
cord-285180-32bxx94u	79	11	using	use	VBG
cord-285180-32bxx94u	79	12	lysis	lysis	NN
cord-285180-32bxx94u	79	13	buffer	buffer	NN
cord-285180-32bxx94u	79	14	as	as	IN
cord-285180-32bxx94u	79	15	described	describe	VBN
cord-285180-32bxx94u	79	16	previously	previously	RB
cord-285180-32bxx94u	79	17	.	.	.
cord-285180-32bxx94u	80	1	For	for	IN
cord-285180-32bxx94u	80	2	cell	cell	NN
cord-285180-32bxx94u	80	3	fractionation	fractionation	NN
cord-285180-32bxx94u	80	4	,	,	,
cord-285180-32bxx94u	80	5	PK	PK	NNP
cord-285180-32bxx94u	80	6	-	-	HYPH
cord-285180-32bxx94u	80	7	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	80	8	-	-	HYPH
cord-285180-32bxx94u	80	9	N	n	CD
cord-285180-32bxx94u	80	10	cells	cell	NNS
cord-285180-32bxx94u	80	11	were	be	VBD
cord-285180-32bxx94u	80	12	fractionated	fractionate	VBN
cord-285180-32bxx94u	80	13	using	use	VBG
cord-285180-32bxx94u	80	14	the	the	DT
cord-285180-32bxx94u	80	15	Nuclear	Nuclear	NNP
cord-285180-32bxx94u	80	16	/	/	SYM
cord-285180-32bxx94u	80	17	Cytosol	Cytosol	NNP
cord-285180-32bxx94u	80	18	Fractionation	Fractionation	NNP
cord-285180-32bxx94u	80	19	Kit	kit	NN
cord-285180-32bxx94u	80	20	(	(	-LRB-
cord-285180-32bxx94u	80	21	BioVision	BioVision	NNP
cord-285180-32bxx94u	80	22	,	,	,
cord-285180-32bxx94u	80	23	Mountain	Mountain	NNP
cord-285180-32bxx94u	80	24	View	View	NNP
cord-285180-32bxx94u	80	25	,	,	,
cord-285180-32bxx94u	80	26	CA	CA	NNP
cord-285180-32bxx94u	80	27	)	)	-RRB-
cord-285180-32bxx94u	80	28	according	accord	VBG
cord-285180-32bxx94u	80	29	to	to	IN
cord-285180-32bxx94u	80	30	the	the	DT
cord-285180-32bxx94u	80	31	manufacturer	manufacturer	NN
cord-285180-32bxx94u	80	32	's	's	POS
cord-285180-32bxx94u	80	33	manuals	manual	NNS
cord-285180-32bxx94u	80	34	.	.	.
cord-285180-32bxx94u	81	1	The	the	DT
cord-285180-32bxx94u	81	2	protein	protein	NN
cord-285180-32bxx94u	81	3	concentrations	concentration	NNS
cord-285180-32bxx94u	81	4	of	of	IN
cord-285180-32bxx94u	81	5	the	the	DT
cord-285180-32bxx94u	81	6	cell	cell	NN
cord-285180-32bxx94u	81	7	lysates	lysate	NNS
cord-285180-32bxx94u	81	8	were	be	VBD
cord-285180-32bxx94u	81	9	determined	determine	VBN
cord-285180-32bxx94u	81	10	using	use	VBG
cord-285180-32bxx94u	81	11	the	the	DT
cord-285180-32bxx94u	81	12	BCA	BCA	NNP
cord-285180-32bxx94u	81	13	protein	protein	NN
cord-285180-32bxx94u	81	14	assay	assay	NN
cord-285180-32bxx94u	81	15	(	(	-LRB-
cord-285180-32bxx94u	81	16	Pierce	Pierce	NNP
cord-285180-32bxx94u	81	17	,	,	,
cord-285180-32bxx94u	81	18	Rockford	Rockford	NNP
cord-285180-32bxx94u	81	19	,	,	,
cord-285180-32bxx94u	81	20	IL	IL	NNP
cord-285180-32bxx94u	81	21	)	)	-RRB-
cord-285180-32bxx94u	81	22	.	.	.
cord-285180-32bxx94u	82	1	The	the	DT
cord-285180-32bxx94u	82	2	cell	cell	NN
cord-285180-32bxx94u	82	3	lysates	lysate	NNS
cord-285180-32bxx94u	82	4	were	be	VBD
cord-285180-32bxx94u	82	5	mixed	mix	VBN
cord-285180-32bxx94u	82	6	with	with	IN
cord-285180-32bxx94u	82	7	4×	4×	CD
cord-285180-32bxx94u	82	8	NuPAGE	NuPAGE	NNP
cord-285180-32bxx94u	82	9	sample	sample	NN
cord-285180-32bxx94u	82	10	buffer	buffer	NN
cord-285180-32bxx94u	82	11	(	(	-LRB-
cord-285180-32bxx94u	82	12	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	82	13	)	)	-RRB-
cord-285180-32bxx94u	82	14	and	and	CC
cord-285180-32bxx94u	82	15	boiled	boil	VBD
cord-285180-32bxx94u	82	16	at	at	IN
cord-285180-32bxx94u	82	17	70	70	CD
cord-285180-32bxx94u	83	1	•	•	NNP
cord-285180-32bxx94u	83	2	C	C	NNP
cord-285180-32bxx94u	83	3	for	for	IN
cord-285180-32bxx94u	83	4	10	10	CD
cord-285180-32bxx94u	83	5	min	min	NN
cord-285180-32bxx94u	83	6	.	.	.
cord-285180-32bxx94u	84	1	Equal	equal	JJ
cord-285180-32bxx94u	84	2	amounts	amount	NNS
cord-285180-32bxx94u	84	3	of	of	IN
cord-285180-32bxx94u	84	4	total	total	JJ
cord-285180-32bxx94u	84	5	protein	protein	NN
cord-285180-32bxx94u	84	6	were	be	VBD
cord-285180-32bxx94u	84	7	separated	separate	VBN
cord-285180-32bxx94u	84	8	in	in	IN
cord-285180-32bxx94u	84	9	a	a	DT
cord-285180-32bxx94u	84	10	NuPAGE	NuPAGE	NNP
cord-285180-32bxx94u	84	11	4	4	CD
cord-285180-32bxx94u	84	12	-	-	SYM
cord-285180-32bxx94u	84	13	12	12	CD
cord-285180-32bxx94u	84	14	%	%	NN
cord-285180-32bxx94u	84	15	Gradient	Gradient	NNP
cord-285180-32bxx94u	84	16	Bis	Bis	NNP
cord-285180-32bxx94u	84	17	-	-	HYPH
cord-285180-32bxx94u	84	18	Tris	Tris	NNP
cord-285180-32bxx94u	84	19	Gel	Gel	NNP
cord-285180-32bxx94u	84	20	(	(	-LRB-
cord-285180-32bxx94u	84	21	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	84	22	)	)	-RRB-
cord-285180-32bxx94u	84	23	under	under	IN
cord-285180-32bxx94u	84	24	non	non	JJ
cord-285180-32bxx94u	84	25	-	-	JJ
cord-285180-32bxx94u	84	26	reducing	reducing	JJ
cord-285180-32bxx94u	84	27	or	or	CC
cord-285180-32bxx94u	84	28	reducing	reduce	VBG
cord-285180-32bxx94u	84	29	conditions	condition	NNS
cord-285180-32bxx94u	84	30	,	,	,
cord-285180-32bxx94u	84	31	and	and	CC
cord-285180-32bxx94u	84	32	electrotransferred	electrotransferre	VBN
cord-285180-32bxx94u	84	33	onto	onto	IN
cord-285180-32bxx94u	84	34	an	an	DT
cord-285180-32bxx94u	84	35	Immobilon	Immobilon	NNP
cord-285180-32bxx94u	84	36	-	-	HYPH
cord-285180-32bxx94u	84	37	P	p	NN
cord-285180-32bxx94u	84	38	membrane	membrane	NN
cord-285180-32bxx94u	84	39	(	(	-LRB-
cord-285180-32bxx94u	84	40	Millipore	Millipore	NNP
cord-285180-32bxx94u	84	41	,	,	,
cord-285180-32bxx94u	84	42	Billerica	Billerica	NNP
cord-285180-32bxx94u	84	43	,	,	,
cord-285180-32bxx94u	84	44	MA	MA	NNP
cord-285180-32bxx94u	84	45	)	)	-RRB-
cord-285180-32bxx94u	84	46	.	.	.
cord-285180-32bxx94u	85	1	The	the	DT
cord-285180-32bxx94u	85	2	membranes	membrane	NNS
cord-285180-32bxx94u	85	3	were	be	VBD
cord-285180-32bxx94u	85	4	blocked	block	VBN
cord-285180-32bxx94u	85	5	with	with	IN
cord-285180-32bxx94u	85	6	3	3	CD
cord-285180-32bxx94u	85	7	%	%	NN
cord-285180-32bxx94u	85	8	powdered	powdered	JJ
cord-285180-32bxx94u	85	9	skim	skim	NN
cord-285180-32bxx94u	85	10	milk	milk	NN
cord-285180-32bxx94u	85	11	(	(	-LRB-
cord-285180-32bxx94u	85	12	BD	BD	NNP
cord-285180-32bxx94u	85	13	Biosciences	Biosciences	NNP
cord-285180-32bxx94u	85	14	)	)	-RRB-
cord-285180-32bxx94u	85	15	in	in	IN
cord-285180-32bxx94u	85	16	TBS	TBS	NNP
cord-285180-32bxx94u	85	17	(	(	-LRB-
cord-285180-32bxx94u	85	18	10	10	CD
cord-285180-32bxx94u	85	19	mM	mM	NNP
cord-285180-32bxx94u	85	20	Tris	Tris	NNP
cord-285180-32bxx94u	85	21	-	-	HYPH
cord-285180-32bxx94u	85	22	HCl	HCl	NNP
cord-285180-32bxx94u	85	23	[	[	-LRB-
cord-285180-32bxx94u	85	24	pH	pH	NNP
cord-285180-32bxx94u	85	25	8.0	8.0	CD
cord-285180-32bxx94u	85	26	]	]	-RRB-
cord-285180-32bxx94u	85	27	,	,	,
cord-285180-32bxx94u	85	28	150	150	CD
cord-285180-32bxx94u	85	29	mM	mm	CD
cord-285180-32bxx94u	85	30	NaCl	NaCl	NNP
cord-285180-32bxx94u	85	31	)	)	-RRB-
cord-285180-32bxx94u	85	32	with	with	IN
cord-285180-32bxx94u	85	33	0.05	0.05	CD
cord-285180-32bxx94u	85	34	%	%	NN
cord-285180-32bxx94u	85	35	Tween-20	Tween-20	NNP
cord-285180-32bxx94u	85	36	(	(	-LRB-
cord-285180-32bxx94u	85	37	TBST	TBST	NNP
cord-285180-32bxx94u	85	38	)	)	-RRB-
cord-285180-32bxx94u	85	39	at	at	IN
cord-285180-32bxx94u	85	40	4	4	CD
cord-285180-32bxx94u	85	41	•	•	NN
cord-285180-32bxx94u	85	42	C	c	NN
cord-285180-32bxx94u	85	43	for	for	IN
cord-285180-32bxx94u	85	44	2	2	CD
cord-285180-32bxx94u	85	45	h	h	NN
cord-285180-32bxx94u	85	46	and	and	CC
cord-285180-32bxx94u	85	47	reacted	react	VBD
cord-285180-32bxx94u	85	48	with	with	IN
cord-285180-32bxx94u	85	49	the	the	DT
cord-285180-32bxx94u	85	50	primary	primary	JJ
cord-285180-32bxx94u	85	51	antibody	antibody	NN
cord-285180-32bxx94u	85	52	against	against	IN
cord-285180-32bxx94u	85	53	the	the	DT
cord-285180-32bxx94u	85	54	6×	6×	CD
cord-285180-32bxx94u	86	1	His	-PRON-	PRP$
cord-285180-32bxx94u	86	2	-	-	HYPH
cord-285180-32bxx94u	86	3	tag	tag	NN
cord-285180-32bxx94u	86	4	,	,	,
cord-285180-32bxx94u	86	5	GRP78	GRP78	NNP
cord-285180-32bxx94u	86	6	,	,	,
cord-285180-32bxx94u	86	7	HSC70	HSC70	NNP
cord-285180-32bxx94u	86	8	,	,	,
cord-285180-32bxx94u	86	9	or	or	CC
cord-285180-32bxx94u	86	10	␤	␤	.
cord-285180-32bxx94u	87	1	-actin	-actin	NFP
cord-285180-32bxx94u	88	1	at	at	IN
cord-285180-32bxx94u	89	1	4	4	LS
cord-285180-32bxx94u	89	2	•	•	NN
cord-285180-32bxx94u	89	3	C	C	NNP
cord-285180-32bxx94u	89	4	overnight	overnight	RB
cord-285180-32bxx94u	89	5	.	.	.
cord-285180-32bxx94u	90	1	The	the	DT
cord-285180-32bxx94u	90	2	blots	blot	NNS
cord-285180-32bxx94u	90	3	were	be	VBD
cord-285180-32bxx94u	90	4	then	then	RB
cord-285180-32bxx94u	90	5	incubated	incubate	VBN
cord-285180-32bxx94u	90	6	with	with	IN
cord-285180-32bxx94u	90	7	a	a	DT
cord-285180-32bxx94u	90	8	horseradish	horseradish	NN
cord-285180-32bxx94u	90	9	peroxidase	peroxidase	NN
cord-285180-32bxx94u	90	10	(	(	-LRB-
cord-285180-32bxx94u	90	11	HRP)-labeled	hrp)-labele	VBN
cord-285180-32bxx94u	90	12	goat	goat	NN
cord-285180-32bxx94u	90	13	anti	anti	JJ
cord-285180-32bxx94u	90	14	-	-	JJ
cord-285180-32bxx94u	90	15	mouse	mouse	JJ
cord-285180-32bxx94u	90	16	IgG	IgG	NNP
cord-285180-32bxx94u	90	17	or	or	CC
cord-285180-32bxx94u	90	18	goat	goat	NNP
cord-285180-32bxx94u	90	19	anti	anti	JJ
cord-285180-32bxx94u	90	20	-	-	JJ
cord-285180-32bxx94u	90	21	rabbit	rabbit	JJ
cord-285180-32bxx94u	90	22	IgG	IgG	NNP
cord-285180-32bxx94u	90	23	antibody	antibody	NN
cord-285180-32bxx94u	90	24	(	(	-LRB-
cord-285180-32bxx94u	90	25	Santa	Santa	NNP
cord-285180-32bxx94u	90	26	Cruz	Cruz	NNP
cord-285180-32bxx94u	90	27	Biotechnology	Biotechnology	NNP
cord-285180-32bxx94u	90	28	)	)	-RRB-
cord-285180-32bxx94u	90	29	at	at	IN
cord-285180-32bxx94u	90	30	the	the	DT
cord-285180-32bxx94u	90	31	dilution	dilution	NN
cord-285180-32bxx94u	90	32	of	of	IN
cord-285180-32bxx94u	90	33	1:2000	1:2000	CD
cord-285180-32bxx94u	90	34	for	for	IN
cord-285180-32bxx94u	90	35	2	2	CD
cord-285180-32bxx94u	90	36	h	h	NN
cord-285180-32bxx94u	90	37	at	at	IN
cord-285180-32bxx94u	90	38	4	4	CD
cord-285180-32bxx94u	91	1	•	•	NNP
cord-285180-32bxx94u	92	1	C.	C.	NNP
cord-285180-32bxx94u	93	1	Finally	finally	RB
cord-285180-32bxx94u	93	2	,	,	,
cord-285180-32bxx94u	93	3	the	the	DT
cord-285180-32bxx94u	93	4	proteins	protein	NNS
cord-285180-32bxx94u	93	5	were	be	VBD
cord-285180-32bxx94u	93	6	visualized	visualize	VBN
cord-285180-32bxx94u	93	7	by	by	IN
cord-285180-32bxx94u	93	8	enhanced	enhance	VBN
cord-285180-32bxx94u	93	9	chemiluminescence	chemiluminescence	NN
cord-285180-32bxx94u	93	10	(	(	-LRB-
cord-285180-32bxx94u	93	11	ECL	ECL	NNP
cord-285180-32bxx94u	93	12	)	)	-RRB-
cord-285180-32bxx94u	93	13	Reagents	reagent	NNS
cord-285180-32bxx94u	93	14	(	(	-LRB-
cord-285180-32bxx94u	93	15	Amersham	Amersham	NNP
cord-285180-32bxx94u	93	16	Biosciences	Biosciences	NNP
cord-285180-32bxx94u	93	17	,	,	,
cord-285180-32bxx94u	93	18	Piscataway	Piscataway	NNP
cord-285180-32bxx94u	93	19	,	,	,
cord-285180-32bxx94u	93	20	NJ	NJ	NNP
cord-285180-32bxx94u	93	21	)	)	-RRB-
cord-285180-32bxx94u	93	22	according	accord	VBG
cord-285180-32bxx94u	93	23	to	to	IN
cord-285180-32bxx94u	93	24	the	the	DT
cord-285180-32bxx94u	93	25	instructions	instruction	NNS
cord-285180-32bxx94u	93	26	of	of	IN
cord-285180-32bxx94u	93	27	the	the	DT
cord-285180-32bxx94u	93	28	manufacturer	manufacturer	NN
cord-285180-32bxx94u	93	29	.	.	.
cord-285180-32bxx94u	94	1	To	to	TO
cord-285180-32bxx94u	94	2	analyze	analyze	VB
cord-285180-32bxx94u	94	3	the	the	DT
cord-285180-32bxx94u	94	4	expression	expression	NN
cord-285180-32bxx94u	94	5	kinetics	kinetic	NNS
cord-285180-32bxx94u	94	6	of	of	IN
cord-285180-32bxx94u	94	7	cellular	cellular	JJ
cord-285180-32bxx94u	94	8	proteins	protein	NNS
cord-285180-32bxx94u	94	9	in	in	IN
cord-285180-32bxx94u	94	10	PK	PK	NNP
cord-285180-32bxx94u	94	11	-	-	HYPH
cord-285180-32bxx94u	94	12	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	94	13	-	-	HYPH
cord-285180-32bxx94u	94	14	N	n	CD
cord-285180-32bxx94u	94	15	cells	cell	NNS
cord-285180-32bxx94u	94	16	,	,	,
cord-285180-32bxx94u	94	17	the	the	DT
cord-285180-32bxx94u	94	18	band	band	NN
cord-285180-32bxx94u	94	19	density	density	NN
cord-285180-32bxx94u	94	20	of	of	IN
cord-285180-32bxx94u	94	21	each	each	DT
cord-285180-32bxx94u	94	22	protein	protein	NN
cord-285180-32bxx94u	94	23	was	be	VBD
cord-285180-32bxx94u	94	24	quantified	quantify	VBN
cord-285180-32bxx94u	94	25	relative	relative	JJ
cord-285180-32bxx94u	94	26	to	to	IN
cord-285180-32bxx94u	94	27	␤	␤	.
cord-285180-32bxx94u	95	1	-actin	-actin	NFP
cord-285180-32bxx94u	95	2	using	use	VBG
cord-285180-32bxx94u	95	3	densitometry	densitometry	NN
cord-285180-32bxx94u	95	4	with	with	IN
cord-285180-32bxx94u	95	5	the	the	DT
cord-285180-32bxx94u	95	6	Wright	Wright	NNP
cord-285180-32bxx94u	95	7	Cell	Cell	NNP
cord-285180-32bxx94u	95	8	Imaging	Imaging	NNP
cord-285180-32bxx94u	95	9	Facility	Facility	NNP
cord-285180-32bxx94u	95	10	(	(	-LRB-
cord-285180-32bxx94u	95	11	WCIF	WCIF	NNP
cord-285180-32bxx94u	95	12	)	)	-RRB-
cord-285180-32bxx94u	95	13	version	version	NN
cord-285180-32bxx94u	95	14	of	of	IN
cord-285180-32bxx94u	95	15	the	the	DT
cord-285180-32bxx94u	95	16	ImageJ	ImageJ	NNP
cord-285180-32bxx94u	95	17	software	software	NN
cord-285180-32bxx94u	95	18	package	package	NN
cord-285180-32bxx94u	95	19	(	(	-LRB-
cord-285180-32bxx94u	95	20	http://www	http://www	NNP
cord-285180-32bxx94u	95	21	.	.	.
cord-285180-32bxx94u	95	22	uhnresearch.ca/facilities/wcif/imagej/	uhnresearch.ca/facilities/wcif/imagej/	NNP
cord-285180-32bxx94u	95	23	)	)	-RRB-
cord-285180-32bxx94u	95	24	.	.	.
cord-285180-32bxx94u	96	1	A	a	DT
cord-285180-32bxx94u	96	2	chemical	chemical	JJ
cord-285180-32bxx94u	96	3	cross	cross	NN
cord-285180-32bxx94u	96	4	-	-	JJ
cord-285180-32bxx94u	96	5	linking	linking	JJ
cord-285180-32bxx94u	96	6	assay	assay	NN
cord-285180-32bxx94u	96	7	was	be	VBD
cord-285180-32bxx94u	96	8	performed	perform	VBN
cord-285180-32bxx94u	96	9	as	as	IN
cord-285180-32bxx94u	96	10	described	describe	VBN
cord-285180-32bxx94u	96	11	previously	previously	RB
cord-285180-32bxx94u	96	12	.	.	.
cord-285180-32bxx94u	97	1	Briefly	briefly	RB
cord-285180-32bxx94u	97	2	,	,	,
cord-285180-32bxx94u	97	3	PK	PK	NNP
cord-285180-32bxx94u	97	4	-	-	HYPH
cord-285180-32bxx94u	97	5	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	97	6	-	-	HYPH
cord-285180-32bxx94u	97	7	N	n	CD
cord-285180-32bxx94u	97	8	cells	cell	NNS
cord-285180-32bxx94u	97	9	and	and	CC
cord-285180-32bxx94u	97	10	PAM	PAM	NNP
cord-285180-32bxx94u	97	11	-	-	HYPH
cord-285180-32bxx94u	97	12	pCD163-N	pcd163-n	NN
cord-285180-32bxx94u	97	13	cells	cell	NNS
cord-285180-32bxx94u	97	14	were	be	VBD
cord-285180-32bxx94u	97	15	grown	grow	VBN
cord-285180-32bxx94u	97	16	in	in	IN
cord-285180-32bxx94u	97	17	a	a	DT
cord-285180-32bxx94u	97	18	6-well	6-well	CD
cord-285180-32bxx94u	97	19	tissue	tissue	NN
cord-285180-32bxx94u	97	20	culture	culture	NN
cord-285180-32bxx94u	97	21	plate	plate	NN
cord-285180-32bxx94u	97	22	for	for	IN
cord-285180-32bxx94u	97	23	48	48	CD
cord-285180-32bxx94u	97	24	h.	h.	NN
cord-285180-32bxx94u	98	1	For	for	IN
cord-285180-32bxx94u	98	2	cross	cross	JJ
cord-285180-32bxx94u	98	3	-	-	JJ
cord-285180-32bxx94u	98	4	linking	linking	JJ
cord-285180-32bxx94u	98	5	studies	study	NNS
cord-285180-32bxx94u	98	6	,	,	,
cord-285180-32bxx94u	98	7	the	the	DT
cord-285180-32bxx94u	98	8	cells	cell	NNS
cord-285180-32bxx94u	98	9	were	be	VBD
cord-285180-32bxx94u	98	10	washed	wash	VBN
cord-285180-32bxx94u	98	11	twice	twice	RB
cord-285180-32bxx94u	98	12	with	with	IN
cord-285180-32bxx94u	98	13	cold	cold	JJ
cord-285180-32bxx94u	98	14	PBS	PBS	NNP
cord-285180-32bxx94u	98	15	and	and	CC
cord-285180-32bxx94u	98	16	then	then	RB
cord-285180-32bxx94u	98	17	incubated	incubate	VBN
cord-285180-32bxx94u	98	18	at	at	IN
cord-285180-32bxx94u	98	19	RT	RT	NNP
cord-285180-32bxx94u	98	20	for	for	IN
cord-285180-32bxx94u	98	21	30	30	CD
cord-285180-32bxx94u	98	22	min	min	NN
cord-285180-32bxx94u	98	23	with	with	IN
cord-285180-32bxx94u	98	24	a	a	DT
cord-285180-32bxx94u	98	25	2	2	CD
cord-285180-32bxx94u	98	26	mM	mm	CD
cord-285180-32bxx94u	98	27	solution	solution	NN
cord-285180-32bxx94u	98	28	of	of	IN
cord-285180-32bxx94u	98	29	a	a	DT
cord-285180-32bxx94u	98	30	membrane	membrane	NN
cord-285180-32bxx94u	98	31	permeable	permeable	JJ
cord-285180-32bxx94u	98	32	and	and	CC
cord-285180-32bxx94u	98	33	thiol	thiol	NN
cord-285180-32bxx94u	98	34	-	-	HYPH
cord-285180-32bxx94u	98	35	cleavable	cleavable	NN
cord-285180-32bxx94u	98	36	cross	cross	NN
cord-285180-32bxx94u	98	37	-	-	NN
cord-285180-32bxx94u	98	38	linker	linker	JJ
cord-285180-32bxx94u	98	39	,	,	,
cord-285180-32bxx94u	98	40	3,3dithiobis(succinimidyl	3,3dithiobis(succinimidyl	CD
cord-285180-32bxx94u	98	41	propionate	propionate	NN
cord-285180-32bxx94u	98	42	)	)	-RRB-
cord-285180-32bxx94u	98	43	(	(	-LRB-
cord-285180-32bxx94u	98	44	DSP	DSP	NNP
cord-285180-32bxx94u	98	45	;	;	:
cord-285180-32bxx94u	98	46	Pierce	Pierce	NNP
cord-285180-32bxx94u	98	47	)	)	-RRB-
cord-285180-32bxx94u	98	48	,	,	,
cord-285180-32bxx94u	98	49	dissolved	dissolve	VBN
cord-285180-32bxx94u	98	50	in	in	IN
cord-285180-32bxx94u	98	51	10	10	CD
cord-285180-32bxx94u	98	52	%	%	NN
cord-285180-32bxx94u	98	53	dimethyl	dimethyl	NN
cord-285180-32bxx94u	98	54	sulfoxide	sulfoxide	NN
cord-285180-32bxx94u	98	55	(	(	-LRB-
cord-285180-32bxx94u	98	56	v	v	NN
cord-285180-32bxx94u	98	57	/	/	SYM
cord-285180-32bxx94u	98	58	v	v	NN
cord-285180-32bxx94u	98	59	in	in	IN
cord-285180-32bxx94u	98	60	PBS	PBS	NNP
cord-285180-32bxx94u	98	61	)	)	-RRB-
cord-285180-32bxx94u	98	62	.	.	.
cord-285180-32bxx94u	99	1	The	the	DT
cord-285180-32bxx94u	99	2	reaction	reaction	NN
cord-285180-32bxx94u	99	3	was	be	VBD
cord-285180-32bxx94u	99	4	quenched	quench	VBN
cord-285180-32bxx94u	99	5	with	with	IN
cord-285180-32bxx94u	99	6	50	50	CD
cord-285180-32bxx94u	99	7	mM	mm	CD
cord-285180-32bxx94u	99	8	Tris	Tris	NNP
cord-285180-32bxx94u	99	9	-	-	HYPH
cord-285180-32bxx94u	99	10	HCl	HCl	NNP
cord-285180-32bxx94u	99	11	[	[	-LRB-
cord-285180-32bxx94u	99	12	pH	pH	NNP
cord-285180-32bxx94u	99	13	7.5	7.5	CD
cord-285180-32bxx94u	99	14	]	]	-RRB-
cord-285180-32bxx94u	99	15	and	and	CC
cord-285180-32bxx94u	99	16	incubated	incubate	VBN
cord-285180-32bxx94u	99	17	for	for	IN
cord-285180-32bxx94u	99	18	an	an	DT
cord-285180-32bxx94u	99	19	additional	additional	JJ
cord-285180-32bxx94u	99	20	15	15	CD
cord-285180-32bxx94u	99	21	min	min	NN
cord-285180-32bxx94u	99	22	.	.	.
cord-285180-32bxx94u	100	1	The	the	DT
cord-285180-32bxx94u	100	2	cells	cell	NNS
cord-285180-32bxx94u	100	3	were	be	VBD
cord-285180-32bxx94u	100	4	lysed	lyse	VBN
cord-285180-32bxx94u	100	5	with	with	IN
cord-285180-32bxx94u	100	6	lysis	lysis	NN
cord-285180-32bxx94u	100	7	buffer	buffer	NN
cord-285180-32bxx94u	100	8	,	,	,
cord-285180-32bxx94u	100	9	and	and	CC
cord-285180-32bxx94u	100	10	the	the	DT
cord-285180-32bxx94u	100	11	resultant	resultant	JJ
cord-285180-32bxx94u	100	12	cell	cell	NN
cord-285180-32bxx94u	100	13	lysates	lysate	NNS
cord-285180-32bxx94u	100	14	were	be	VBD
cord-285180-32bxx94u	100	15	then	then	RB
cord-285180-32bxx94u	100	16	subjected	subject	VBN
cord-285180-32bxx94u	100	17	to	to	IN
cord-285180-32bxx94u	100	18	a	a	DT
cord-285180-32bxx94u	100	19	Western	western	JJ
cord-285180-32bxx94u	100	20	blot	blot	NN
cord-285180-32bxx94u	100	21	assay	assay	NN
cord-285180-32bxx94u	100	22	as	as	IN
cord-285180-32bxx94u	100	23	described	describe	VBN
cord-285180-32bxx94u	100	24	above	above	RB
cord-285180-32bxx94u	100	25	.	.	.
cord-285180-32bxx94u	101	1	Pellets	pellet	NNS
cord-285180-32bxx94u	101	2	of	of	IN
cord-285180-32bxx94u	101	3	cultured	cultured	JJ
cord-285180-32bxx94u	101	4	cells	cell	NNS
cord-285180-32bxx94u	101	5	were	be	VBD
cord-285180-32bxx94u	101	6	washed	wash	VBN
cord-285180-32bxx94u	101	7	twice	twice	RB
cord-285180-32bxx94u	101	8	with	with	IN
cord-285180-32bxx94u	101	9	ice	ice	NN
cord-285180-32bxx94u	101	10	-	-	HYPH
cord-285180-32bxx94u	101	11	cold	cold	JJ
cord-285180-32bxx94u	101	12	PBS	PBS	NNP
cord-285180-32bxx94u	101	13	,	,	,
cord-285180-32bxx94u	101	14	placed	place	VBN
cord-285180-32bxx94u	101	15	in	in	IN
cord-285180-32bxx94u	101	16	sample	sample	NN
cord-285180-32bxx94u	101	17	lysis	lysis	NN
cord-285180-32bxx94u	101	18	solution	solution	NN
cord-285180-32bxx94u	101	19	consisting	consist	VBG
cord-285180-32bxx94u	101	20	of	of	IN
cord-285180-32bxx94u	101	21	7	7	CD
cord-285180-32bxx94u	101	22	M	M	NNP
cord-285180-32bxx94u	101	23	urea	urea	NN
cord-285180-32bxx94u	101	24	,	,	,
cord-285180-32bxx94u	101	25	2	2	CD
cord-285180-32bxx94u	101	26	M	m	CD
cord-285180-32bxx94u	101	27	thiourea	thiourea	NN
cord-285180-32bxx94u	101	28	,	,	,
cord-285180-32bxx94u	101	29	4	4	CD
cord-285180-32bxx94u	101	30	%	%	NN
cord-285180-32bxx94u	101	31	3-[(3-cholamidopropyl	3-[(3-cholamidopropyl	CD
cord-285180-32bxx94u	101	32	)	)	-RRB-
cord-285180-32bxx94u	101	33	dimethyammonio]-1propanesulfonate	dimethyammonio]-1propanesulfonate	JJ
cord-285180-32bxx94u	101	34	(	(	-LRB-
cord-285180-32bxx94u	101	35	CHAPS	CHAPS	NNP
cord-285180-32bxx94u	101	36	)	)	-RRB-
cord-285180-32bxx94u	101	37	,	,	,
cord-285180-32bxx94u	101	38	1	1	CD
cord-285180-32bxx94u	101	39	%	%	NN
cord-285180-32bxx94u	101	40	dithiothreitol	dithiothreitol	NN
cord-285180-32bxx94u	101	41	(	(	-LRB-
cord-285180-32bxx94u	101	42	DTT	DTT	NNP
cord-285180-32bxx94u	101	43	)	)	-RRB-
cord-285180-32bxx94u	101	44	,	,	,
cord-285180-32bxx94u	101	45	2	2	CD
cord-285180-32bxx94u	101	46	%	%	NN
cord-285180-32bxx94u	101	47	pharmalyte	pharmalyte	NNP
cord-285180-32bxx94u	101	48	(	(	-LRB-
cord-285180-32bxx94u	101	49	pH	pH	NNP
cord-285180-32bxx94u	101	50	3.5	3.5	CD
cord-285180-32bxx94u	101	51	-	-	SYM
cord-285180-32bxx94u	101	52	10	10	CD
cord-285180-32bxx94u	101	53	,	,	,
cord-285180-32bxx94u	101	54	Amersham	Amersham	NNP
cord-285180-32bxx94u	101	55	Biosciences	Biosciences	NNP
cord-285180-32bxx94u	101	56	)	)	-RRB-
cord-285180-32bxx94u	101	57	,	,	,
cord-285180-32bxx94u	101	58	and	and	CC
cord-285180-32bxx94u	101	59	1	1	CD
cord-285180-32bxx94u	101	60	mM	mm	CD
cord-285180-32bxx94u	101	61	benzamidine	benzamidine	NN
cord-285180-32bxx94u	101	62	,	,	,
cord-285180-32bxx94u	101	63	and	and	CC
cord-285180-32bxx94u	101	64	were	be	VBD
cord-285180-32bxx94u	101	65	then	then	RB
cord-285180-32bxx94u	101	66	sonicated	sonicate	VBN
cord-285180-32bxx94u	101	67	for	for	IN
cord-285180-32bxx94u	101	68	10	10	CD
cord-285180-32bxx94u	101	69	s	s	NNPS
cord-285180-32bxx94u	101	70	using	use	VBG
cord-285180-32bxx94u	101	71	a	a	DT
cord-285180-32bxx94u	101	72	Sonoplus	Sonoplus	NNP
cord-285180-32bxx94u	101	73	device	device	NN
cord-285180-32bxx94u	101	74	(	(	-LRB-
cord-285180-32bxx94u	101	75	Bandelin	Bandelin	NNP
cord-285180-32bxx94u	101	76	Electronic	Electronic	NNP
cord-285180-32bxx94u	101	77	,	,	,
cord-285180-32bxx94u	101	78	Germany	Germany	NNP
cord-285180-32bxx94u	101	79	)	)	-RRB-
cord-285180-32bxx94u	101	80	.	.	.
cord-285180-32bxx94u	102	1	The	the	DT
cord-285180-32bxx94u	102	2	samples	sample	NNS
cord-285180-32bxx94u	102	3	were	be	VBD
cord-285180-32bxx94u	102	4	subsequently	subsequently	RB
cord-285180-32bxx94u	102	5	incubated	incubate	VBN
cord-285180-32bxx94u	102	6	for	for	IN
cord-285180-32bxx94u	102	7	1	1	CD
cord-285180-32bxx94u	102	8	h	h	NN
cord-285180-32bxx94u	102	9	at	at	IN
cord-285180-32bxx94u	102	10	4	4	CD
cord-285180-32bxx94u	102	11	•	•	NN
cord-285180-32bxx94u	102	12	C.	c.	NN
cord-285180-32bxx94u	103	1	After	after	IN
cord-285180-32bxx94u	103	2	centrifugation	centrifugation	NN
cord-285180-32bxx94u	103	3	at	at	IN
cord-285180-32bxx94u	103	4	15,000	15,000	CD
cord-285180-32bxx94u	103	5	×	×	NN
cord-285180-32bxx94u	103	6	g	g	NN
cord-285180-32bxx94u	103	7	for	for	IN
cord-285180-32bxx94u	103	8	1	1	CD
cord-285180-32bxx94u	103	9	h	h	NN
cord-285180-32bxx94u	103	10	at	at	IN
cord-285180-32bxx94u	103	11	4	4	CD
cord-285180-32bxx94u	103	12	•	•	NN
cord-285180-32bxx94u	103	13	C	c	NN
cord-285180-32bxx94u	103	14	,	,	,
cord-285180-32bxx94u	103	15	insoluble	insoluble	JJ
cord-285180-32bxx94u	103	16	cellular	cellular	JJ
cord-285180-32bxx94u	103	17	debris	debris	NN
cord-285180-32bxx94u	103	18	were	be	VBD
cord-285180-32bxx94u	103	19	discarded	discard	VBN
cord-285180-32bxx94u	103	20	,	,	,
cord-285180-32bxx94u	103	21	and	and	CC
cord-285180-32bxx94u	103	22	the	the	DT
cord-285180-32bxx94u	103	23	supernatant	supernatant	NN
cord-285180-32bxx94u	103	24	was	be	VBD
cord-285180-32bxx94u	103	25	collected	collect	VBN
cord-285180-32bxx94u	103	26	and	and	CC
cord-285180-32bxx94u	103	27	stored	store	VBN
cord-285180-32bxx94u	103	28	at	at	IN
cord-285180-32bxx94u	103	29	−80	−80	NNP
cord-285180-32bxx94u	104	1	•	•	NNP
cord-285180-32bxx94u	104	2	C	C	NNP
cord-285180-32bxx94u	104	3	until	until	IN
cord-285180-32bxx94u	104	4	use	use	NN
cord-285180-32bxx94u	104	5	.	.	.
cord-285180-32bxx94u	105	1	The	the	DT
cord-285180-32bxx94u	105	2	protein	protein	NN
cord-285180-32bxx94u	105	3	concentrations	concentration	NNS
cord-285180-32bxx94u	105	4	were	be	VBD
cord-285180-32bxx94u	105	5	measured	measure	VBN
cord-285180-32bxx94u	105	6	by	by	IN
cord-285180-32bxx94u	105	7	the	the	DT
cord-285180-32bxx94u	105	8	Bradford	Bradford	NNP
cord-285180-32bxx94u	105	9	assay	assay	NN
cord-285180-32bxx94u	105	10	as	as	IN
cord-285180-32bxx94u	105	11	described	describe	VBN
cord-285180-32bxx94u	105	12	previously	previously	RB
cord-285180-32bxx94u	105	13	(	(	-LRB-
cord-285180-32bxx94u	105	14	Bradford	Bradford	NNP
cord-285180-32bxx94u	105	15	,	,	,
cord-285180-32bxx94u	105	16	1976	1976	CD
cord-285180-32bxx94u	105	17	)	)	-RRB-
cord-285180-32bxx94u	105	18	.	.	.
cord-285180-32bxx94u	106	1	Protein	protein	NN
cord-285180-32bxx94u	106	2	samples	sample	NNS
cord-285180-32bxx94u	106	3	were	be	VBD
cord-285180-32bxx94u	106	4	analyzed	analyze	VBN
cord-285180-32bxx94u	106	5	by	by	IN
cord-285180-32bxx94u	106	6	2DE	2DE	NNP
cord-285180-32bxx94u	106	7	using	use	VBG
cord-285180-32bxx94u	106	8	commercial	commercial	JJ
cord-285180-32bxx94u	106	9	IPG	IPG	NNP
cord-285180-32bxx94u	106	10	dry	dry	JJ
cord-285180-32bxx94u	106	11	strips	strip	NNS
cord-285180-32bxx94u	106	12	(	(	-LRB-
cord-285180-32bxx94u	106	13	pH	pH	NNP
cord-285180-32bxx94u	106	14	4	4	CD
cord-285180-32bxx94u	106	15	-	-	SYM
cord-285180-32bxx94u	106	16	10	10	CD
cord-285180-32bxx94u	106	17	,	,	,
cord-285180-32bxx94u	106	18	24	24	CD
cord-285180-32bxx94u	106	19	cm	cm	NNS
cord-285180-32bxx94u	106	20	;	;	:
cord-285180-32bxx94u	106	21	Genomine	Genomine	NNP
cord-285180-32bxx94u	106	22	Inc.	Inc.	NNP
cord-285180-32bxx94u	106	23	,	,	,
cord-285180-32bxx94u	106	24	Pohang	Pohang	NNP
cord-285180-32bxx94u	106	25	,	,	,
cord-285180-32bxx94u	106	26	South	South	NNP
cord-285180-32bxx94u	106	27	Korea	Korea	NNP
cord-285180-32bxx94u	106	28	)	)	-RRB-
cord-285180-32bxx94u	106	29	for	for	IN
cord-285180-32bxx94u	106	30	the	the	DT
cord-285180-32bxx94u	106	31	first	first	JJ
cord-285180-32bxx94u	106	32	-	-	HYPH
cord-285180-32bxx94u	106	33	dimensional	dimensional	JJ
cord-285180-32bxx94u	106	34	separation	separation	NN
cord-285180-32bxx94u	106	35	(	(	-LRB-
cord-285180-32bxx94u	106	36	isoelectric	isoelectric	VBN
cord-285180-32bxx94u	106	37	focusing	focus	VBG
cord-285180-32bxx94u	106	38	;	;	:
cord-285180-32bxx94u	106	39	IEF	IEF	NNP
cord-285180-32bxx94u	106	40	)	)	-RRB-
cord-285180-32bxx94u	106	41	and	and	CC
cord-285180-32bxx94u	106	42	sodium	sodium	NN
cord-285180-32bxx94u	106	43	dodecyl	dodecyl	NNP
cord-285180-32bxx94u	106	44	sulfate	sulfate	NN
cord-285180-32bxx94u	106	45	-	-	HYPH
cord-285180-32bxx94u	106	46	polyacrylamide	polyacrylamide	NN
cord-285180-32bxx94u	106	47	gel	gel	NN
cord-285180-32bxx94u	106	48	electrophoresis	electrophoresis	NN
cord-285180-32bxx94u	106	49	(	(	-LRB-
cord-285180-32bxx94u	106	50	SDS	SDS	NNP
cord-285180-32bxx94u	106	51	-	-	HYPH
cord-285180-32bxx94u	106	52	PAGE	PAGE	NNP
cord-285180-32bxx94u	106	53	)	)	-RRB-
cord-285180-32bxx94u	106	54	for	for	IN
cord-285180-32bxx94u	106	55	the	the	DT
cord-285180-32bxx94u	106	56	second	second	JJ
cord-285180-32bxx94u	106	57	dimension	dimension	NN
cord-285180-32bxx94u	106	58	.	.	.
cord-285180-32bxx94u	107	1	The	the	DT
cord-285180-32bxx94u	107	2	IPG	IPG	NNP
cord-285180-32bxx94u	107	3	dry	dry	JJ
cord-285180-32bxx94u	107	4	strips	strip	NNS
cord-285180-32bxx94u	107	5	were	be	VBD
cord-285180-32bxx94u	107	6	loaded	load	VBN
cord-285180-32bxx94u	107	7	independently	independently	RB
cord-285180-32bxx94u	107	8	with	with	IN
cord-285180-32bxx94u	107	9	200	200	CD
cord-285180-32bxx94u	107	10	g	g	NN
cord-285180-32bxx94u	107	11	of	of	IN
cord-285180-32bxx94u	107	12	each	each	DT
cord-285180-32bxx94u	107	13	protein	protein	NN
cord-285180-32bxx94u	107	14	sample	sample	NN
cord-285180-32bxx94u	107	15	and	and	CC
cord-285180-32bxx94u	107	16	rehydrated	rehydrate	VBN
cord-285180-32bxx94u	107	17	overnight	overnight	RB
cord-285180-32bxx94u	107	18	in	in	IN
cord-285180-32bxx94u	107	19	rehydration	rehydration	NN
cord-285180-32bxx94u	107	20	buffer	buffer	NN
cord-285180-32bxx94u	107	21	(	(	-LRB-
cord-285180-32bxx94u	107	22	7	7	CD
cord-285180-32bxx94u	107	23	M	M	NNP
cord-285180-32bxx94u	107	24	urea	urea	NN
cord-285180-32bxx94u	107	25	,	,	,
cord-285180-32bxx94u	107	26	2	2	CD
cord-285180-32bxx94u	107	27	M	m	CD
cord-285180-32bxx94u	107	28	thiourea	thiourea	NN
cord-285180-32bxx94u	107	29	,	,	,
cord-285180-32bxx94u	107	30	2	2	CD
cord-285180-32bxx94u	107	31	%	%	NN
cord-285180-32bxx94u	107	32	CHAPS	chap	NNS
cord-285180-32bxx94u	107	33	,	,	,
cord-285180-32bxx94u	107	34	1	1	CD
cord-285180-32bxx94u	107	35	%	%	NN
cord-285180-32bxx94u	107	36	DTT	DTT	NNP
cord-285180-32bxx94u	107	37	,	,	,
cord-285180-32bxx94u	107	38	and	and	CC
cord-285180-32bxx94u	107	39	1	1	CD
cord-285180-32bxx94u	107	40	%	%	NN
cord-285180-32bxx94u	107	41	pharmalyte	pharmalyte	NNP
cord-285180-32bxx94u	107	42	)	)	-RRB-
cord-285180-32bxx94u	107	43	.	.	.
cord-285180-32bxx94u	108	1	IEF	IEF	NNP
cord-285180-32bxx94u	108	2	was	be	VBD
cord-285180-32bxx94u	108	3	performed	perform	VBN
cord-285180-32bxx94u	108	4	at	at	IN
cord-285180-32bxx94u	108	5	20	20	CD
cord-285180-32bxx94u	108	6	•	•	NN
cord-285180-32bxx94u	108	7	C	c	NN
cord-285180-32bxx94u	108	8	using	use	VBG
cord-285180-32bxx94u	108	9	a	a	DT
cord-285180-32bxx94u	108	10	Multiphor	Multiphor	NNP
cord-285180-32bxx94u	108	11	II	II	NNP
cord-285180-32bxx94u	108	12	electrophoresis	electrophoresis	NN
cord-285180-32bxx94u	108	13	unit	unit	NN
cord-285180-32bxx94u	108	14	and	and	CC
cord-285180-32bxx94u	108	15	an	an	DT
cord-285180-32bxx94u	108	16	EPS	EPS	NNP
cord-285180-32bxx94u	108	17	3500	3500	CD
cord-285180-32bxx94u	108	18	XL	XL	NNP
cord-285180-32bxx94u	108	19	power	power	NN
cord-285180-32bxx94u	108	20	supply	supply	NN
cord-285180-32bxx94u	108	21	(	(	-LRB-
cord-285180-32bxx94u	108	22	Amersham	Amersham	NNP
cord-285180-32bxx94u	108	23	Biosciences	Biosciences	NNP
cord-285180-32bxx94u	108	24	)	)	-RRB-
cord-285180-32bxx94u	108	25	with	with	IN
cord-285180-32bxx94u	108	26	the	the	DT
cord-285180-32bxx94u	108	27	following	follow	VBG
cord-285180-32bxx94u	108	28	parameters	parameter	NNS
cord-285180-32bxx94u	108	29	:	:	:
cord-285180-32bxx94u	108	30	gradient	gradient	NN
cord-285180-32bxx94u	108	31	increase	increase	NN
cord-285180-32bxx94u	108	32	from	from	IN
cord-285180-32bxx94u	108	33	150	150	CD
cord-285180-32bxx94u	108	34	to	to	TO
cord-285180-32bxx94u	108	35	3500	3500	CD
cord-285180-32bxx94u	108	36	V	v	NN
cord-285180-32bxx94u	108	37	for	for	IN
cord-285180-32bxx94u	108	38	3	3	CD
cord-285180-32bxx94u	108	39	h	h	NN
cord-285180-32bxx94u	108	40	and	and	CC
cord-285180-32bxx94u	108	41	3500	3500	CD
cord-285180-32bxx94u	108	42	V	v	NN
cord-285180-32bxx94u	108	43	for	for	IN
cord-285180-32bxx94u	108	44	a	a	DT
cord-285180-32bxx94u	108	45	total	total	NN
cord-285180-32bxx94u	108	46	of	of	IN
cord-285180-32bxx94u	108	47	96,000	96,000	CD
cord-285180-32bxx94u	108	48	V	v	NN
cord-285180-32bxx94u	108	49	h.	h.	NN
cord-285180-32bxx94u	109	1	Following	follow	VBG
cord-285180-32bxx94u	109	2	IEF	IEF	NNP
cord-285180-32bxx94u	109	3	separation	separation	NN
cord-285180-32bxx94u	109	4	,	,	,
cord-285180-32bxx94u	109	5	the	the	DT
cord-285180-32bxx94u	109	6	IPG	IPG	NNP
cord-285180-32bxx94u	109	7	strips	strip	NNS
cord-285180-32bxx94u	109	8	were	be	VBD
cord-285180-32bxx94u	109	9	incubated	incubate	VBN
cord-285180-32bxx94u	109	10	for	for	IN
cord-285180-32bxx94u	109	11	10	10	CD
cord-285180-32bxx94u	109	12	min	min	NN
cord-285180-32bxx94u	109	13	at	at	IN
cord-285180-32bxx94u	109	14	RT	RT	NNP
cord-285180-32bxx94u	109	15	with	with	IN
cord-285180-32bxx94u	109	16	gentle	gentle	JJ
cord-285180-32bxx94u	109	17	shaking	shaking	NN
cord-285180-32bxx94u	109	18	in	in	IN
cord-285180-32bxx94u	109	19	equilibration	equilibration	NN
cord-285180-32bxx94u	109	20	buffer	buffer	NN
cord-285180-32bxx94u	109	21	(	(	-LRB-
cord-285180-32bxx94u	109	22	50	50	CD
cord-285180-32bxx94u	109	23	mM	mM	NNP
cord-285180-32bxx94u	109	24	Tris	Tris	NNP
cord-285180-32bxx94u	109	25	-	-	HYPH
cord-285180-32bxx94u	109	26	Cl	Cl	NNP
cord-285180-32bxx94u	109	27	pH	pH	NNP
cord-285180-32bxx94u	109	28	6.8	6.8	CD
cord-285180-32bxx94u	109	29	,	,	,
cord-285180-32bxx94u	109	30	containing	contain	VBG
cord-285180-32bxx94u	109	31	6	6	CD
cord-285180-32bxx94u	109	32	M	M	NNP
cord-285180-32bxx94u	109	33	urea	urea	NN
cord-285180-32bxx94u	109	34	,	,	,
cord-285180-32bxx94u	110	1	2	2	CD
cord-285180-32bxx94u	110	2	%	%	NN
cord-285180-32bxx94u	110	3	SDS	SDS	NNP
cord-285180-32bxx94u	110	4	,	,	,
cord-285180-32bxx94u	110	5	and	and	CC
cord-285180-32bxx94u	110	6	30	30	CD
cord-285180-32bxx94u	110	7	%	%	NN
cord-285180-32bxx94u	110	8	glycerol	glycerol	NN
cord-285180-32bxx94u	110	9	)	)	-RRB-
cord-285180-32bxx94u	110	10	containing	contain	VBG
cord-285180-32bxx94u	110	11	1	1	CD
cord-285180-32bxx94u	110	12	%	%	NN
cord-285180-32bxx94u	110	13	DTT	DTT	NNP
cord-285180-32bxx94u	110	14	and	and	CC
cord-285180-32bxx94u	110	15	were	be	VBD
cord-285180-32bxx94u	110	16	subsequently	subsequently	RB
cord-285180-32bxx94u	110	17	incubated	incubate	VBN
cord-285180-32bxx94u	110	18	in	in	IN
cord-285180-32bxx94u	110	19	the	the	DT
cord-285180-32bxx94u	110	20	equilibration	equilibration	NN
cord-285180-32bxx94u	110	21	buffer	buffer	NN
cord-285180-32bxx94u	110	22	containing	contain	VBG
cord-285180-32bxx94u	110	23	2.5	2.5	CD
cord-285180-32bxx94u	110	24	%	%	NN
cord-285180-32bxx94u	110	25	iodoacetamide	iodoacetamide	NN
cord-285180-32bxx94u	110	26	under	under	IN
cord-285180-32bxx94u	110	27	the	the	DT
cord-285180-32bxx94u	110	28	same	same	JJ
cord-285180-32bxx94u	110	29	conditions	condition	NNS
cord-285180-32bxx94u	110	30	.	.	.
cord-285180-32bxx94u	111	1	Each	each	DT
cord-285180-32bxx94u	111	2	equilibrated	equilibrated	JJ
cord-285180-32bxx94u	111	3	strip	strip	NN
cord-285180-32bxx94u	111	4	was	be	VBD
cord-285180-32bxx94u	111	5	then	then	RB
cord-285180-32bxx94u	111	6	inserted	insert	VBN
cord-285180-32bxx94u	111	7	into	into	IN
cord-285180-32bxx94u	111	8	10	10	CD
cord-285180-32bxx94u	111	9	-	-	SYM
cord-285180-32bxx94u	111	10	16	16	CD
cord-285180-32bxx94u	111	11	%	%	NN
cord-285180-32bxx94u	111	12	polyacrylamide	polyacrylamide	NN
cord-285180-32bxx94u	111	13	gels	gel	NNS
cord-285180-32bxx94u	111	14	(	(	-LRB-
cord-285180-32bxx94u	111	15	20	20	CD
cord-285180-32bxx94u	111	16	cm	cm	NNS
cord-285180-32bxx94u	111	17	×	×	NNP
cord-285180-32bxx94u	111	18	24	24	CD
cord-285180-32bxx94u	111	19	cm	cm	NNS
cord-285180-32bxx94u	111	20	)	)	-RRB-
cord-285180-32bxx94u	111	21	and	and	CC
cord-285180-32bxx94u	111	22	SDS	SDS	NNP
cord-285180-32bxx94u	111	23	-	-	HYPH
cord-285180-32bxx94u	111	24	PAGE	PAGE	NNP
cord-285180-32bxx94u	111	25	was	be	VBD
cord-285180-32bxx94u	111	26	run	run	VBN
cord-285180-32bxx94u	111	27	using	use	VBG
cord-285180-32bxx94u	111	28	a	a	DT
cord-285180-32bxx94u	111	29	Hoefer	Hoefer	NNP
cord-285180-32bxx94u	111	30	DALT	DALT	NNP
cord-285180-32bxx94u	111	31	2D	2d	NN
cord-285180-32bxx94u	111	32	system	system	NN
cord-285180-32bxx94u	111	33	(	(	-LRB-
cord-285180-32bxx94u	111	34	Amersham	Amersham	NNP
cord-285180-32bxx94u	111	35	Biosciences	Biosciences	NNP
cord-285180-32bxx94u	111	36	)	)	-RRB-
cord-285180-32bxx94u	111	37	at	at	IN
cord-285180-32bxx94u	111	38	20	20	CD
cord-285180-32bxx94u	111	39	•	•	NN
cord-285180-32bxx94u	111	40	C	c	NN
cord-285180-32bxx94u	111	41	for	for	IN
cord-285180-32bxx94u	111	42	1700	1700	CD
cord-285180-32bxx94u	111	43	V	v	NN
cord-285180-32bxx94u	111	44	h	h	NN
cord-285180-32bxx94u	111	45	according	accord	VBG
cord-285180-32bxx94u	111	46	to	to	IN
cord-285180-32bxx94u	111	47	the	the	DT
cord-285180-32bxx94u	111	48	manufacturer	manufacturer	NN
cord-285180-32bxx94u	111	49	's	's	POS
cord-285180-32bxx94u	111	50	instructions	instruction	NNS
cord-285180-32bxx94u	111	51	.	.	.
cord-285180-32bxx94u	112	1	The	the	DT
cord-285180-32bxx94u	112	2	2D	2d	NN
cord-285180-32bxx94u	112	3	gels	gel	NNS
cord-285180-32bxx94u	112	4	were	be	VBD
cord-285180-32bxx94u	112	5	stained	stain	VBN
cord-285180-32bxx94u	112	6	by	by	IN
cord-285180-32bxx94u	112	7	the	the	DT
cord-285180-32bxx94u	112	8	silver	silver	JJ
cord-285180-32bxx94u	112	9	staining	staining	NN
cord-285180-32bxx94u	112	10	method	method	NN
cord-285180-32bxx94u	112	11	as	as	IN
cord-285180-32bxx94u	112	12	described	describe	VBN
cord-285180-32bxx94u	112	13	previously	previously	RB
cord-285180-32bxx94u	112	14	with	with	IN
cord-285180-32bxx94u	112	15	some	some	DT
cord-285180-32bxx94u	112	16	modifications	modification	NNS
cord-285180-32bxx94u	112	17	(	(	-LRB-
cord-285180-32bxx94u	112	18	Oakley	Oakley	NNP
cord-285180-32bxx94u	112	19	et	et	NNP
cord-285180-32bxx94u	112	20	al	al	NNP
cord-285180-32bxx94u	112	21	.	.	NNP
cord-285180-32bxx94u	112	22	,	,	,
cord-285180-32bxx94u	112	23	1980	1980	CD
cord-285180-32bxx94u	112	24	)	)	-RRB-
cord-285180-32bxx94u	112	25	.	.	.
cord-285180-32bxx94u	113	1	To	to	TO
cord-285180-32bxx94u	113	2	compensate	compensate	VB
cord-285180-32bxx94u	113	3	for	for	IN
cord-285180-32bxx94u	113	4	the	the	DT
cord-285180-32bxx94u	113	5	variability	variability	NN
cord-285180-32bxx94u	113	6	of	of	IN
cord-285180-32bxx94u	113	7	2DE	2de	CD
cord-285180-32bxx94u	113	8	,	,	,
cord-285180-32bxx94u	113	9	three	three	CD
cord-285180-32bxx94u	113	10	independent	independent	JJ
cord-285180-32bxx94u	113	11	experiments	experiment	NNS
cord-285180-32bxx94u	113	12	were	be	VBD
cord-285180-32bxx94u	113	13	conducted	conduct	VBN
cord-285180-32bxx94u	113	14	for	for	IN
cord-285180-32bxx94u	113	15	further	further	JJ
cord-285180-32bxx94u	113	16	statistical	statistical	JJ
cord-285180-32bxx94u	113	17	analysis	analysis	NN
cord-285180-32bxx94u	113	18	.	.	.
cord-285180-32bxx94u	114	1	The	the	DT
cord-285180-32bxx94u	114	2	stained	stained	JJ
cord-285180-32bxx94u	114	3	gels	gel	NNS
cord-285180-32bxx94u	114	4	were	be	VBD
cord-285180-32bxx94u	114	5	imaged	image	VBN
cord-285180-32bxx94u	114	6	using	use	VBG
cord-285180-32bxx94u	114	7	a	a	DT
cord-285180-32bxx94u	114	8	high	high	JJ
cord-285180-32bxx94u	114	9	-	-	HYPH
cord-285180-32bxx94u	114	10	resolution	resolution	NN
cord-285180-32bxx94u	114	11	2D	2D	NNP
cord-285180-32bxx94u	114	12	gel	gel	NNP
cord-285180-32bxx94u	114	13	CCD	CCD	NNP
cord-285180-32bxx94u	114	14	image	image	NN
cord-285180-32bxx94u	114	15	analyzer	analyzer	NN
cord-285180-32bxx94u	114	16	,	,	,
cord-285180-32bxx94u	114	17	Dyversity	Dyversity	NNP
cord-285180-32bxx94u	114	18	(	(	-LRB-
cord-285180-32bxx94u	114	19	Syngene	Syngene	NNP
cord-285180-32bxx94u	114	20	,	,	,
cord-285180-32bxx94u	114	21	Frederick	Frederick	NNP
cord-285180-32bxx94u	114	22	,	,	,
cord-285180-32bxx94u	114	23	MD	MD	NNP
cord-285180-32bxx94u	114	24	)	)	-RRB-
cord-285180-32bxx94u	114	25	,	,	,
cord-285180-32bxx94u	114	26	and	and	CC
cord-285180-32bxx94u	114	27	quantitative	quantitative	JJ
cord-285180-32bxx94u	114	28	analysis	analysis	NN
cord-285180-32bxx94u	114	29	of	of	IN
cord-285180-32bxx94u	114	30	the	the	DT
cord-285180-32bxx94u	114	31	digitized	digitized	JJ
cord-285180-32bxx94u	114	32	gel	gel	NN
cord-285180-32bxx94u	114	33	images	image	NNS
cord-285180-32bxx94u	114	34	was	be	VBD
cord-285180-32bxx94u	114	35	carried	carry	VBN
cord-285180-32bxx94u	114	36	out	out	RP
cord-285180-32bxx94u	114	37	using	use	VBG
cord-285180-32bxx94u	114	38	the	the	DT
cord-285180-32bxx94u	114	39	PDQuest	pdqu	JJS
cord-285180-32bxx94u	114	40	software	software	NN
cord-285180-32bxx94u	114	41	(	(	-LRB-
cord-285180-32bxx94u	114	42	version	version	NN
cord-285180-32bxx94u	114	43	7.0	7.0	CD
cord-285180-32bxx94u	114	44	,	,	,
cord-285180-32bxx94u	114	45	Bio	Bio	NNP
cord-285180-32bxx94u	114	46	-	-	HYPH
cord-285180-32bxx94u	114	47	Rad	Rad	NNP
cord-285180-32bxx94u	114	48	,	,	,
cord-285180-32bxx94u	114	49	Hercules	Hercules	NNP
cord-285180-32bxx94u	114	50	,	,	,
cord-285180-32bxx94u	114	51	CA	CA	NNP
cord-285180-32bxx94u	114	52	)	)	-RRB-
cord-285180-32bxx94u	114	53	according	accord	VBG
cord-285180-32bxx94u	114	54	to	to	IN
cord-285180-32bxx94u	114	55	the	the	DT
cord-285180-32bxx94u	114	56	protocols	protocol	NNS
cord-285180-32bxx94u	114	57	provided	provide	VBN
cord-285180-32bxx94u	114	58	by	by	IN
cord-285180-32bxx94u	114	59	the	the	DT
cord-285180-32bxx94u	114	60	manufacturer	manufacturer	NN
cord-285180-32bxx94u	114	61	.	.	.
cord-285180-32bxx94u	115	1	Data	datum	NNS
cord-285180-32bxx94u	115	2	representing	represent	VBG
cord-285180-32bxx94u	115	3	3	3	CD
cord-285180-32bxx94u	115	4	independent	independent	JJ
cord-285180-32bxx94u	115	5	2DE	2de	CD
cord-285180-32bxx94u	115	6	experiments	experiment	NNS
cord-285180-32bxx94u	115	7	for	for	IN
cord-285180-32bxx94u	115	8	each	each	DT
cord-285180-32bxx94u	115	9	sample	sample	NN
cord-285180-32bxx94u	115	10	were	be	VBD
cord-285180-32bxx94u	115	11	statistically	statistically	RB
cord-285180-32bxx94u	115	12	analyzed	analyze	VBN
cord-285180-32bxx94u	115	13	using	use	VBG
cord-285180-32bxx94u	115	14	Student	Student	NNP
cord-285180-32bxx94u	115	15	's	's	POS
cord-285180-32bxx94u	115	16	t	t	NN
cord-285180-32bxx94u	115	17	-	-	HYPH
cord-285180-32bxx94u	115	18	test	test	NN
cord-285180-32bxx94u	115	19	,	,	,
cord-285180-32bxx94u	115	20	and	and	CC
cord-285180-32bxx94u	115	21	p	p	NN
cord-285180-32bxx94u	115	22	-	-	HYPH
cord-285180-32bxx94u	115	23	values	value	NNS
cord-285180-32bxx94u	115	24	of	of	IN
cord-285180-32bxx94u	115	25	less	less	JJR
cord-285180-32bxx94u	115	26	than	than	IN
cord-285180-32bxx94u	115	27	0.05	0.05	CD
cord-285180-32bxx94u	115	28	were	be	VBD
cord-285180-32bxx94u	115	29	considered	consider	VBN
cord-285180-32bxx94u	115	30	to	to	TO
cord-285180-32bxx94u	115	31	be	be	VB
cord-285180-32bxx94u	115	32	statistically	statistically	RB
cord-285180-32bxx94u	115	33	significant	significant	JJ
cord-285180-32bxx94u	115	34	.	.	.
cord-285180-32bxx94u	116	1	The	the	DT
cord-285180-32bxx94u	116	2	quantitative	quantitative	JJ
cord-285180-32bxx94u	116	3	data	datum	NNS
cord-285180-32bxx94u	116	4	from	from	IN
cord-285180-32bxx94u	116	5	each	each	DT
cord-285180-32bxx94u	116	6	protein	protein	NN
cord-285180-32bxx94u	116	7	spot	spot	NN
cord-285180-32bxx94u	116	8	were	be	VBD
cord-285180-32bxx94u	116	9	normalized	normalize	VBN
cord-285180-32bxx94u	116	10	based	base	VBN
cord-285180-32bxx94u	116	11	on	on	IN
cord-285180-32bxx94u	116	12	the	the	DT
cord-285180-32bxx94u	116	13	total	total	JJ
cord-285180-32bxx94u	116	14	valid	valid	JJ
cord-285180-32bxx94u	116	15	spot	spot	NN
cord-285180-32bxx94u	116	16	intensity	intensity	NN
cord-285180-32bxx94u	116	17	for	for	IN
cord-285180-32bxx94u	116	18	each	each	DT
cord-285180-32bxx94u	116	19	gel	gel	NN
cord-285180-32bxx94u	116	20	.	.	.
cord-285180-32bxx94u	117	1	Only	only	RB
cord-285180-32bxx94u	117	2	protein	protein	NN
cord-285180-32bxx94u	117	3	spots	spot	NNS
cord-285180-32bxx94u	117	4	that	that	WDT
cord-285180-32bxx94u	117	5	showed	show	VBD
cord-285180-32bxx94u	117	6	significant	significant	JJ
cord-285180-32bxx94u	117	7	differential	differential	JJ
cord-285180-32bxx94u	117	8	expression	expression	NN
cord-285180-32bxx94u	117	9	(	(	-LRB-
cord-285180-32bxx94u	117	10	p	p	NN
cord-285180-32bxx94u	117	11	<	<	XX
cord-285180-32bxx94u	117	12	0.05	0.05	CD
cord-285180-32bxx94u	117	13	)	)	-RRB-
cord-285180-32bxx94u	117	14	with	with	IN
cord-285180-32bxx94u	117	15	a	a	DT
cord-285180-32bxx94u	117	16	±2-fold	±2-fold	JJ
cord-285180-32bxx94u	117	17	consistent	consistent	JJ
cord-285180-32bxx94u	117	18	change	change	NN
cord-285180-32bxx94u	117	19	in	in	IN
cord-285180-32bxx94u	117	20	the	the	DT
cord-285180-32bxx94u	117	21	expression	expression	NN
cord-285180-32bxx94u	117	22	level	level	NN
cord-285180-32bxx94u	117	23	in	in	IN
cord-285180-32bxx94u	117	24	comparison	comparison	NN
cord-285180-32bxx94u	117	25	with	with	IN
cord-285180-32bxx94u	117	26	the	the	DT
cord-285180-32bxx94u	117	27	control	control	NN
cord-285180-32bxx94u	117	28	sample	sample	NN
cord-285180-32bxx94u	117	29	were	be	VBD
cord-285180-32bxx94u	117	30	selected	select	VBN
cord-285180-32bxx94u	117	31	for	for	IN
cord-285180-32bxx94u	117	32	mass	mass	NN
cord-285180-32bxx94u	117	33	spectrometry	spectrometry	NN
cord-285180-32bxx94u	117	34	(	(	-LRB-
cord-285180-32bxx94u	117	35	MS	MS	NNP
cord-285180-32bxx94u	117	36	)	)	-RRB-
cord-285180-32bxx94u	117	37	analysis	analysis	NN
cord-285180-32bxx94u	117	38	.	.	.
cord-285180-32bxx94u	118	1	Each	each	DT
cord-285180-32bxx94u	118	2	selected	select	VBN
cord-285180-32bxx94u	118	3	protein	protein	NN
cord-285180-32bxx94u	118	4	spot	spot	NN
cord-285180-32bxx94u	118	5	was	be	VBD
cord-285180-32bxx94u	118	6	excised	excise	VBN
cord-285180-32bxx94u	118	7	manually	manually	RB
cord-285180-32bxx94u	118	8	from	from	IN
cord-285180-32bxx94u	118	9	the	the	DT
cord-285180-32bxx94u	118	10	silverstained	silverstained	JJ
cord-285180-32bxx94u	118	11	gels	gel	NNS
cord-285180-32bxx94u	118	12	and	and	CC
cord-285180-32bxx94u	118	13	was	be	VBD
cord-285180-32bxx94u	118	14	enzymatically	enzymatically	RB
cord-285180-32bxx94u	118	15	digested	digest	VBN
cord-285180-32bxx94u	118	16	in	in	IN
cord-285180-32bxx94u	118	17	-	-	HYPH
cord-285180-32bxx94u	118	18	gel	gel	NN
cord-285180-32bxx94u	118	19	as	as	IN
cord-285180-32bxx94u	118	20	previously	previously	RB
cord-285180-32bxx94u	118	21	described	describe	VBN
cord-285180-32bxx94u	119	1	(	(	-LRB-
cord-285180-32bxx94u	119	2	Shevchenko	Shevchenko	NNP
cord-285180-32bxx94u	119	3	et	et	NNP
cord-285180-32bxx94u	119	4	al	al	NNP
cord-285180-32bxx94u	119	5	.	.	NNP
cord-285180-32bxx94u	119	6	,	,	,
cord-285180-32bxx94u	119	7	1996	1996	CD
cord-285180-32bxx94u	119	8	)	)	-RRB-
cord-285180-32bxx94u	119	9	and	and	CC
cord-285180-32bxx94u	119	10	using	use	VBG
cord-285180-32bxx94u	119	11	modified	modify	VBN
cord-285180-32bxx94u	119	12	porcine	porcine	JJ
cord-285180-32bxx94u	119	13	trypsin	trypsin	NN
cord-285180-32bxx94u	119	14	(	(	-LRB-
cord-285180-32bxx94u	119	15	Sequencing	sequencing	NN
cord-285180-32bxx94u	119	16	grade	grade	NN
cord-285180-32bxx94u	119	17	;	;	:
cord-285180-32bxx94u	119	18	Promega	Promega	NNP
cord-285180-32bxx94u	119	19	,	,	,
cord-285180-32bxx94u	119	20	Madison	Madison	NNP
cord-285180-32bxx94u	119	21	,	,	,
cord-285180-32bxx94u	119	22	WI	WI	NNP
cord-285180-32bxx94u	119	23	)	)	-RRB-
cord-285180-32bxx94u	119	24	.	.	.
cord-285180-32bxx94u	120	1	The	the	DT
cord-285180-32bxx94u	120	2	gel	gel	NN
cord-285180-32bxx94u	120	3	pieces	piece	NNS
cord-285180-32bxx94u	120	4	were	be	VBD
cord-285180-32bxx94u	120	5	washed	wash	VBN
cord-285180-32bxx94u	120	6	with	with	IN
cord-285180-32bxx94u	120	7	50	50	CD
cord-285180-32bxx94u	120	8	%	%	NN
cord-285180-32bxx94u	120	9	acetonitrile	acetonitrile	NN
cord-285180-32bxx94u	120	10	(	(	-LRB-
cord-285180-32bxx94u	120	11	ACN	ACN	NNP
cord-285180-32bxx94u	120	12	)	)	-RRB-
cord-285180-32bxx94u	120	13	,	,	,
cord-285180-32bxx94u	120	14	air	air	NN
cord-285180-32bxx94u	120	15	-	-	HYPH
cord-285180-32bxx94u	120	16	dried	dry	VBN
cord-285180-32bxx94u	120	17	thoroughly	thoroughly	RB
cord-285180-32bxx94u	120	18	at	at	IN
cord-285180-32bxx94u	120	19	RT	RT	NNP
cord-285180-32bxx94u	120	20	,	,	,
cord-285180-32bxx94u	120	21	and	and	CC
cord-285180-32bxx94u	120	22	then	then	RB
cord-285180-32bxx94u	120	23	rehydrated	rehydrate	VBN
cord-285180-32bxx94u	120	24	for	for	IN
cord-285180-32bxx94u	120	25	8	8	CD
cord-285180-32bxx94u	120	26	-	-	SYM
cord-285180-32bxx94u	120	27	10	10	CD
cord-285180-32bxx94u	120	28	h	h	NN
cord-285180-32bxx94u	120	29	at	at	IN
cord-285180-32bxx94u	120	30	37	37	CD
cord-285180-32bxx94u	121	1	•	•	NNP
cord-285180-32bxx94u	121	2	C	C	NNP
cord-285180-32bxx94u	121	3	with	with	IN
cord-285180-32bxx94u	121	4	modified	modify	VBN
cord-285180-32bxx94u	121	5	sequencing	sequencing	NN
cord-285180-32bxx94u	121	6	grade	grade	NN
cord-285180-32bxx94u	121	7	porcine	porcine	JJ
cord-285180-32bxx94u	121	8	trypsin	trypsin	NN
cord-285180-32bxx94u	121	9	(	(	-LRB-
cord-285180-32bxx94u	121	10	8	8	CD
cord-285180-32bxx94u	121	11	-	-	SYM
cord-285180-32bxx94u	121	12	10	10	CD
cord-285180-32bxx94u	121	13	ng	ng	NN
cord-285180-32bxx94u	121	14	/	/	SYM
cord-285180-32bxx94u	121	15	l	l	NN
cord-285180-32bxx94u	121	16	)	)	-RRB-
cord-285180-32bxx94u	121	17	.	.	.
cord-285180-32bxx94u	122	1	The	the	DT
cord-285180-32bxx94u	122	2	proteolytic	proteolytic	JJ
cord-285180-32bxx94u	122	3	reaction	reaction	NN
cord-285180-32bxx94u	122	4	was	be	VBD
cord-285180-32bxx94u	122	5	terminated	terminate	VBN
cord-285180-32bxx94u	122	6	by	by	IN
cord-285180-32bxx94u	122	7	addition	addition	NN
cord-285180-32bxx94u	122	8	of	of	IN
cord-285180-32bxx94u	122	9	5	5	CD
cord-285180-32bxx94u	122	10	l	l	NN
cord-285180-32bxx94u	122	11	of	of	IN
cord-285180-32bxx94u	122	12	0.5	0.5	CD
cord-285180-32bxx94u	122	13	%	%	NN
cord-285180-32bxx94u	122	14	trifluoroacetic	trifluoroacetic	JJ
cord-285180-32bxx94u	122	15	acid	acid	NN
cord-285180-32bxx94u	122	16	(	(	-LRB-
cord-285180-32bxx94u	122	17	TFA	TFA	NNP
cord-285180-32bxx94u	122	18	)	)	-RRB-
cord-285180-32bxx94u	122	19	.	.	.
cord-285180-32bxx94u	123	1	The	the	DT
cord-285180-32bxx94u	123	2	tryptic	tryptic	JJ
cord-285180-32bxx94u	123	3	peptides	peptide	NNS
cord-285180-32bxx94u	123	4	were	be	VBD
cord-285180-32bxx94u	123	5	recovered	recover	VBN
cord-285180-32bxx94u	123	6	by	by	IN
cord-285180-32bxx94u	123	7	combining	combine	VBG
cord-285180-32bxx94u	123	8	the	the	DT
cord-285180-32bxx94u	123	9	aqueous	aqueous	JJ
cord-285180-32bxx94u	123	10	phase	phase	NN
cord-285180-32bxx94u	123	11	from	from	IN
cord-285180-32bxx94u	123	12	several	several	JJ
cord-285180-32bxx94u	123	13	extractions	extraction	NNS
cord-285180-32bxx94u	123	14	of	of	IN
cord-285180-32bxx94u	123	15	gel	gel	NN
cord-285180-32bxx94u	123	16	pieces	piece	NNS
cord-285180-32bxx94u	123	17	with	with	IN
cord-285180-32bxx94u	123	18	50	50	CD
cord-285180-32bxx94u	123	19	%	%	NN
cord-285180-32bxx94u	123	20	aqueous	aqueous	JJ
cord-285180-32bxx94u	123	21	ACN	ACN	NNP
cord-285180-32bxx94u	123	22	.	.	.
cord-285180-32bxx94u	124	1	After	after	IN
cord-285180-32bxx94u	124	2	concentration	concentration	NN
cord-285180-32bxx94u	124	3	,	,	,
cord-285180-32bxx94u	124	4	the	the	DT
cord-285180-32bxx94u	124	5	peptide	peptide	NN
cord-285180-32bxx94u	124	6	mixture	mixture	NN
cord-285180-32bxx94u	124	7	was	be	VBD
cord-285180-32bxx94u	124	8	desalted	desalt	VBN
cord-285180-32bxx94u	124	9	using	use	VBG
cord-285180-32bxx94u	124	10	C	C	NNP
cord-285180-32bxx94u	124	11	18	18	CD
cord-285180-32bxx94u	124	12	ZipTips	ZipTips	NNP
cord-285180-32bxx94u	124	13	(	(	-LRB-
cord-285180-32bxx94u	124	14	Millipore	Millipore	NNP
cord-285180-32bxx94u	124	15	)	)	-RRB-
cord-285180-32bxx94u	124	16	,	,	,
cord-285180-32bxx94u	124	17	and	and	CC
cord-285180-32bxx94u	124	18	the	the	DT
cord-285180-32bxx94u	124	19	peptides	peptide	NNS
cord-285180-32bxx94u	124	20	were	be	VBD
cord-285180-32bxx94u	124	21	eluted	elute	VBN
cord-285180-32bxx94u	124	22	in	in	IN
cord-285180-32bxx94u	124	23	1	1	CD
cord-285180-32bxx94u	124	24	-	-	SYM
cord-285180-32bxx94u	124	25	5	5	CD
cord-285180-32bxx94u	124	26	l	l	NN
cord-285180-32bxx94u	124	27	of	of	IN
cord-285180-32bxx94u	124	28	50	50	CD
cord-285180-32bxx94u	124	29	%	%	NN
cord-285180-32bxx94u	124	30	ACN	ACN	NNP
cord-285180-32bxx94u	124	31	.	.	.
cord-285180-32bxx94u	125	1	An	an	DT
cord-285180-32bxx94u	125	2	aliquot	aliquot	NN
cord-285180-32bxx94u	125	3	of	of	IN
cord-285180-32bxx94u	125	4	this	this	DT
cord-285180-32bxx94u	125	5	solution	solution	NN
cord-285180-32bxx94u	125	6	was	be	VBD
cord-285180-32bxx94u	125	7	mixed	mix	VBN
cord-285180-32bxx94u	125	8	with	with	IN
cord-285180-32bxx94u	125	9	an	an	DT
cord-285180-32bxx94u	125	10	equal	equal	JJ
cord-285180-32bxx94u	125	11	volume	volume	NN
cord-285180-32bxx94u	125	12	of	of	IN
cord-285180-32bxx94u	125	13	a	a	DT
cord-285180-32bxx94u	125	14	saturated	saturated	JJ
cord-285180-32bxx94u	125	15	solution	solution	NN
cord-285180-32bxx94u	125	16	of	of	IN
cord-285180-32bxx94u	125	17	␣	␣	DT
cord-285180-32bxx94u	125	18	-cyano-4-hydroxycinnamic	-cyano-4-hydroxycinnamic	:
cord-285180-32bxx94u	125	19	acid	acid	NN
cord-285180-32bxx94u	125	20	(	(	-LRB-
cord-285180-32bxx94u	125	21	CHCA	CHCA	NNP
cord-285180-32bxx94u	125	22	;	;	:
cord-285180-32bxx94u	125	23	Sigma	Sigma	NNP
cord-285180-32bxx94u	125	24	)	)	-RRB-
cord-285180-32bxx94u	125	25	in	in	IN
cord-285180-32bxx94u	125	26	50	50	CD
cord-285180-32bxx94u	125	27	%	%	NN
cord-285180-32bxx94u	125	28	ACN/0.1	acn/0.1	CD
cord-285180-32bxx94u	125	29	%	%	NN
cord-285180-32bxx94u	125	30	TFA	TFA	NNP
cord-285180-32bxx94u	125	31	,	,	,
cord-285180-32bxx94u	125	32	and	and	CC
cord-285180-32bxx94u	125	33	1	1	CD
cord-285180-32bxx94u	125	34	l	l	NN
cord-285180-32bxx94u	125	35	of	of	IN
cord-285180-32bxx94u	125	36	this	this	DT
cord-285180-32bxx94u	125	37	mixture	mixture	NN
cord-285180-32bxx94u	125	38	was	be	VBD
cord-285180-32bxx94u	125	39	immediately	immediately	RB
cord-285180-32bxx94u	125	40	spotted	spot	VBN
cord-285180-32bxx94u	125	41	onto	onto	IN
cord-285180-32bxx94u	125	42	the	the	DT
cord-285180-32bxx94u	125	43	target	target	NN
cord-285180-32bxx94u	125	44	plate	plate	NN
cord-285180-32bxx94u	125	45	.	.	.
cord-285180-32bxx94u	126	1	MALDI	MALDI	NNP
cord-285180-32bxx94u	126	2	-	-	HYPH
cord-285180-32bxx94u	126	3	TOF	TOF	NNP
cord-285180-32bxx94u	126	4	analysis	analysis	NN
cord-285180-32bxx94u	126	5	was	be	VBD
cord-285180-32bxx94u	126	6	performed	perform	VBN
cord-285180-32bxx94u	126	7	on	on	IN
cord-285180-32bxx94u	126	8	a	a	DT
cord-285180-32bxx94u	126	9	Microflex	Microflex	NNP
cord-285180-32bxx94u	126	10	LRF	LRF	NNP
cord-285180-32bxx94u	126	11	20	20	CD
cord-285180-32bxx94u	126	12	instrument	instrument	NN
cord-285180-32bxx94u	126	13	(	(	-LRB-
cord-285180-32bxx94u	126	14	Bruker	Bruker	NNP
cord-285180-32bxx94u	126	15	Daltonics	Daltonics	NNP
cord-285180-32bxx94u	126	16	,	,	,
cord-285180-32bxx94u	126	17	Billerica	Billerica	NNP
cord-285180-32bxx94u	126	18	,	,	,
cord-285180-32bxx94u	126	19	MA	MA	NNP
cord-285180-32bxx94u	126	20	)	)	-RRB-
cord-285180-32bxx94u	126	21	as	as	IN
cord-285180-32bxx94u	126	22	described	describe	VBN
cord-285180-32bxx94u	126	23	by	by	IN
cord-285180-32bxx94u	126	24	Fernandez	Fernandez	NNP
cord-285180-32bxx94u	126	25	et	et	NNP
cord-285180-32bxx94u	126	26	al	al	NNP
cord-285180-32bxx94u	126	27	.	.	.
cord-285180-32bxx94u	127	1	(	(	-LRB-
cord-285180-32bxx94u	127	2	1998	1998	CD
cord-285180-32bxx94u	127	3	)	)	-RRB-
cord-285180-32bxx94u	127	4	.	.	.
cord-285180-32bxx94u	128	1	The	the	DT
cord-285180-32bxx94u	128	2	spectra	spectrum	NNS
cord-285180-32bxx94u	128	3	were	be	VBD
cord-285180-32bxx94u	128	4	collected	collect	VBN
cord-285180-32bxx94u	128	5	from	from	IN
cord-285180-32bxx94u	128	6	300	300	CD
cord-285180-32bxx94u	128	7	shots	shot	NNS
cord-285180-32bxx94u	128	8	per	per	IN
cord-285180-32bxx94u	128	9	spectrum	spectrum	NN
cord-285180-32bxx94u	128	10	over	over	IN
cord-285180-32bxx94u	128	11	the	the	DT
cord-285180-32bxx94u	128	12	m	m	NNP
cord-285180-32bxx94u	128	13	/	/	SYM
cord-285180-32bxx94u	128	14	z	z	NNP
cord-285180-32bxx94u	128	15	range	range	NNP
cord-285180-32bxx94u	128	16	600	600	CD
cord-285180-32bxx94u	128	17	-	-	HYPH
cord-285180-32bxx94u	128	18	3000	3000	CD
cord-285180-32bxx94u	128	19	and	and	CC
cord-285180-32bxx94u	128	20	calibrated	calibrate	VBN
cord-285180-32bxx94u	128	21	by	by	IN
cord-285180-32bxx94u	128	22	two	two	CD
cord-285180-32bxx94u	128	23	point	point	NN
cord-285180-32bxx94u	128	24	internal	internal	JJ
cord-285180-32bxx94u	128	25	calibration	calibration	NN
cord-285180-32bxx94u	128	26	using	use	VBG
cord-285180-32bxx94u	128	27	trypsin	trypsin	NN
cord-285180-32bxx94u	128	28	auto	auto	NN
cord-285180-32bxx94u	128	29	-	-	HYPH
cord-285180-32bxx94u	128	30	digestion	digestion	NN
cord-285180-32bxx94u	128	31	peaks	peak	NNS
cord-285180-32bxx94u	128	32	(	(	-LRB-
cord-285180-32bxx94u	128	33	m	m	NNP
cord-285180-32bxx94u	128	34	/	/	SYM
cord-285180-32bxx94u	128	35	z	z	NN
cord-285180-32bxx94u	128	36	842.5099	842.5099	NN
cord-285180-32bxx94u	128	37	,	,	,
cord-285180-32bxx94u	128	38	2211.1046	2211.1046	CD
cord-285180-32bxx94u	128	39	)	)	-RRB-
cord-285180-32bxx94u	128	40	.	.	.
cord-285180-32bxx94u	129	1	The	the	DT
cord-285180-32bxx94u	129	2	peak	peak	NN
cord-285180-32bxx94u	129	3	list	list	NN
cord-285180-32bxx94u	129	4	was	be	VBD
cord-285180-32bxx94u	129	5	generated	generate	VBN
cord-285180-32bxx94u	129	6	using	use	VBG
cord-285180-32bxx94u	129	7	Flex	Flex	NNP
cord-285180-32bxx94u	129	8	Analysis	Analysis	NNP
cord-285180-32bxx94u	129	9	3.0	3.0	CD
cord-285180-32bxx94u	129	10	.	.	.
cord-285180-32bxx94u	130	1	We	-PRON-	PRP
cord-285180-32bxx94u	130	2	used	use	VBD
cord-285180-32bxx94u	130	3	the	the	DT
cord-285180-32bxx94u	130	4	following	follow	VBG
cord-285180-32bxx94u	130	5	threshold	threshold	NN
cord-285180-32bxx94u	130	6	for	for	IN
cord-285180-32bxx94u	130	7	peak	peak	NN
cord-285180-32bxx94u	130	8	-	-	HYPH
cord-285180-32bxx94u	130	9	picking	picking	NN
cord-285180-32bxx94u	130	10	:	:	:
cord-285180-32bxx94u	130	11	500	500	CD
cord-285180-32bxx94u	130	12	for	for	IN
cord-285180-32bxx94u	130	13	minimum	minimum	JJ
cord-285180-32bxx94u	130	14	resolution	resolution	NN
cord-285180-32bxx94u	130	15	of	of	IN
cord-285180-32bxx94u	130	16	monoisotopic	monoisotopic	NNP
cord-285180-32bxx94u	130	17	mass	mass	NNP
cord-285180-32bxx94u	130	18	,	,	,
cord-285180-32bxx94u	130	19	5	5	CD
cord-285180-32bxx94u	130	20	for	for	IN
cord-285180-32bxx94u	131	1	S	S	NNP
cord-285180-32bxx94u	131	2	/	/	SYM
cord-285180-32bxx94u	131	3	N.	N.	NNP
cord-285180-32bxx94u	131	4	The	the	DT
cord-285180-32bxx94u	131	5	search	search	NN
cord-285180-32bxx94u	131	6	program	program	NN
cord-285180-32bxx94u	131	7	MASCOT	mascot	NN
cord-285180-32bxx94u	131	8	from	from	IN
cord-285180-32bxx94u	131	9	Matrix	Matrix	NNP
cord-285180-32bxx94u	131	10	Science	Science	NNP
cord-285180-32bxx94u	131	11	(	(	-LRB-
cord-285180-32bxx94u	131	12	http://www.matrixscience.com/	http://www.matrixscience.com/	ADD
cord-285180-32bxx94u	131	13	)	)	-RRB-
cord-285180-32bxx94u	131	14	was	be	VBD
cord-285180-32bxx94u	131	15	used	use	VBN
cord-285180-32bxx94u	131	16	for	for	IN
cord-285180-32bxx94u	131	17	protein	protein	NN
cord-285180-32bxx94u	131	18	identification	identification	NN
cord-285180-32bxx94u	131	19	by	by	IN
cord-285180-32bxx94u	131	20	PMF	PMF	NNP
cord-285180-32bxx94u	131	21	.	.	.
cord-285180-32bxx94u	132	1	The	the	DT
cord-285180-32bxx94u	132	2	following	following	JJ
cord-285180-32bxx94u	132	3	parameters	parameter	NNS
cord-285180-32bxx94u	132	4	were	be	VBD
cord-285180-32bxx94u	132	5	used	use	VBN
cord-285180-32bxx94u	132	6	for	for	IN
cord-285180-32bxx94u	132	7	the	the	DT
cord-285180-32bxx94u	132	8	database	database	NN
cord-285180-32bxx94u	132	9	search	search	NN
cord-285180-32bxx94u	132	10	:	:	:
cord-285180-32bxx94u	132	11	trypsin	trypsin	NN
cord-285180-32bxx94u	132	12	as	as	IN
cord-285180-32bxx94u	132	13	the	the	DT
cord-285180-32bxx94u	132	14	cleaving	cleave	VBG
cord-285180-32bxx94u	132	15	enzyme	enzyme	NN
cord-285180-32bxx94u	132	16	,	,	,
cord-285180-32bxx94u	132	17	a	a	DT
cord-285180-32bxx94u	132	18	maximum	maximum	NN
cord-285180-32bxx94u	132	19	of	of	IN
cord-285180-32bxx94u	132	20	one	one	CD
cord-285180-32bxx94u	132	21	missed	miss	VBN
cord-285180-32bxx94u	132	22	cleavage	cleavage	NN
cord-285180-32bxx94u	132	23	,	,	,
cord-285180-32bxx94u	132	24	iodoacetamide	iodoacetamide	NNP
cord-285180-32bxx94u	132	25	(	(	-LRB-
cord-285180-32bxx94u	132	26	Cys	Cys	NNP
cord-285180-32bxx94u	132	27	)	)	-RRB-
cord-285180-32bxx94u	132	28	as	as	IN
cord-285180-32bxx94u	132	29	a	a	DT
cord-285180-32bxx94u	132	30	complete	complete	JJ
cord-285180-32bxx94u	132	31	modification	modification	NN
cord-285180-32bxx94u	132	32	,	,	,
cord-285180-32bxx94u	132	33	oxidation	oxidation	NN
cord-285180-32bxx94u	132	34	(	(	-LRB-
cord-285180-32bxx94u	132	35	Met	Met	NNP
cord-285180-32bxx94u	132	36	)	)	-RRB-
cord-285180-32bxx94u	132	37	as	as	IN
cord-285180-32bxx94u	132	38	a	a	DT
cord-285180-32bxx94u	132	39	partial	partial	JJ
cord-285180-32bxx94u	132	40	modification	modification	NN
cord-285180-32bxx94u	132	41	,	,	,
cord-285180-32bxx94u	132	42	monoisotopic	monoisotopic	NNP
cord-285180-32bxx94u	132	43	masses	masse	NNS
cord-285180-32bxx94u	132	44	,	,	,
cord-285180-32bxx94u	132	45	and	and	CC
cord-285180-32bxx94u	132	46	a	a	DT
cord-285180-32bxx94u	132	47	mass	mass	JJ
cord-285180-32bxx94u	132	48	tolerance	tolerance	NN
cord-285180-32bxx94u	132	49	of	of	IN
cord-285180-32bxx94u	132	50	±0.1	±0.1	NNP
cord-285180-32bxx94u	132	51	Da	Da	NNP
cord-285180-32bxx94u	132	52	.	.	.
cord-285180-32bxx94u	133	1	The	the	DT
cord-285180-32bxx94u	133	2	PMF	PMF	NNP
cord-285180-32bxx94u	133	3	acceptance	acceptance	NN
cord-285180-32bxx94u	133	4	criterion	criterion	NN
cord-285180-32bxx94u	133	5	was	be	VBD
cord-285180-32bxx94u	133	6	probability	probability	NN
cord-285180-32bxx94u	133	7	scoring	scoring	NN
cord-285180-32bxx94u	133	8	.	.	.
cord-285180-32bxx94u	134	1	Total	Total	NNP
cord-285180-32bxx94u	134	2	RNA	RNA	NNP
cord-285180-32bxx94u	134	3	was	be	VBD
cord-285180-32bxx94u	134	4	extracted	extract	VBN
cord-285180-32bxx94u	134	5	from	from	IN
cord-285180-32bxx94u	134	6	the	the	DT
cord-285180-32bxx94u	134	7	lysates	lysate	NNS
cord-285180-32bxx94u	134	8	of	of	IN
cord-285180-32bxx94u	134	9	PK	PK	NNP
cord-285180-32bxx94u	134	10	-	-	HYPH
cord-285180-32bxx94u	134	11	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	134	12	-	-	HYPH
cord-285180-32bxx94u	134	13	N	n	CD
cord-285180-32bxx94u	134	14	cells	cell	NNS
cord-285180-32bxx94u	134	15	at	at	IN
cord-285180-32bxx94u	134	16	24	24	CD
cord-285180-32bxx94u	134	17	and	and	CC
cord-285180-32bxx94u	134	18	48	48	CD
cord-285180-32bxx94u	134	19	h	h	NN
cord-285180-32bxx94u	134	20	post	post	NN
cord-285180-32bxx94u	134	21	-	-	NN
cord-285180-32bxx94u	134	22	seeding	seeding	NN
cord-285180-32bxx94u	134	23	by	by	IN
cord-285180-32bxx94u	134	24	the	the	DT
cord-285180-32bxx94u	134	25	TRIzol	TRIzol	NNP
cord-285180-32bxx94u	134	26	Reagent	Reagent	NNP
cord-285180-32bxx94u	134	27	(	(	-LRB-
cord-285180-32bxx94u	134	28	Invitrogen	Invitrogen	NNP
cord-285180-32bxx94u	134	29	)	)	-RRB-
cord-285180-32bxx94u	134	30	and	and	CC
cord-285180-32bxx94u	134	31	was	be	VBD
cord-285180-32bxx94u	134	32	treated	treat	VBN
cord-285180-32bxx94u	134	33	with	with	IN
cord-285180-32bxx94u	134	34	DNase	DNase	NNP
cord-285180-32bxx94u	134	35	I	i	NN
cord-285180-32bxx94u	134	36	(	(	-LRB-
cord-285180-32bxx94u	134	37	TaKaRa	takara	XX
cord-285180-32bxx94u	134	38	,	,	,
cord-285180-32bxx94u	134	39	Otsu	Otsu	NNP
cord-285180-32bxx94u	134	40	,	,	,
cord-285180-32bxx94u	134	41	Japan	Japan	NNP
cord-285180-32bxx94u	134	42	)	)	-RRB-
cord-285180-32bxx94u	134	43	according	accord	VBG
cord-285180-32bxx94u	134	44	to	to	IN
cord-285180-32bxx94u	134	45	the	the	DT
cord-285180-32bxx94u	134	46	manufacturer	manufacturer	NN
cord-285180-32bxx94u	134	47	's	's	POS
cord-285180-32bxx94u	134	48	protocols	protocol	NNS
cord-285180-32bxx94u	134	49	.	.	.
cord-285180-32bxx94u	135	1	The	the	DT
cord-285180-32bxx94u	135	2	concentrations	concentration	NNS
cord-285180-32bxx94u	135	3	of	of	IN
cord-285180-32bxx94u	135	4	the	the	DT
cord-285180-32bxx94u	135	5	extracted	extract	VBN
cord-285180-32bxx94u	135	6	RNA	RNA	NNP
cord-285180-32bxx94u	135	7	were	be	VBD
cord-285180-32bxx94u	135	8	measured	measure	VBN
cord-285180-32bxx94u	135	9	using	use	VBG
cord-285180-32bxx94u	135	10	a	a	DT
cord-285180-32bxx94u	135	11	NanoVue	NanoVue	NNP
cord-285180-32bxx94u	135	12	spectrophotometer	spectrophotometer	NN
cord-285180-32bxx94u	135	13	(	(	-LRB-
cord-285180-32bxx94u	135	14	GE	GE	NNP
cord-285180-32bxx94u	135	15	Healthcare	Healthcare	NNP
cord-285180-32bxx94u	135	16	,	,	,
cord-285180-32bxx94u	135	17	Piscataway	Piscataway	NNP
cord-285180-32bxx94u	135	18	,	,	,
cord-285180-32bxx94u	135	19	NJ	NJ	NNP
cord-285180-32bxx94u	135	20	)	)	-RRB-
cord-285180-32bxx94u	135	21	.	.	.
cord-285180-32bxx94u	136	1	Quantitative	quantitative	JJ
cord-285180-32bxx94u	136	2	real	real	JJ
cord-285180-32bxx94u	136	3	-	-	HYPH
cord-285180-32bxx94u	136	4	time	time	NN
cord-285180-32bxx94u	136	5	RT	RT	NNP
cord-285180-32bxx94u	136	6	-	-	HYPH
cord-285180-32bxx94u	136	7	PCR	PCR	NNP
cord-285180-32bxx94u	136	8	was	be	VBD
cord-285180-32bxx94u	136	9	performed	perform	VBN
cord-285180-32bxx94u	136	10	using	use	VBG
cord-285180-32bxx94u	136	11	a	a	DT
cord-285180-32bxx94u	136	12	Thermal	Thermal	NNP
cord-285180-32bxx94u	136	13	Cycler	cycler	NN
cord-285180-32bxx94u	136	14	Dice	Dice	NNP
cord-285180-32bxx94u	136	15	Real	real	JJ
cord-285180-32bxx94u	136	16	Time	time	NN
cord-285180-32bxx94u	136	17	System	system	NN
cord-285180-32bxx94u	136	18	(	(	-LRB-
cord-285180-32bxx94u	136	19	TaKaRa	TaKaRa	NNP
cord-285180-32bxx94u	136	20	)	)	-RRB-
cord-285180-32bxx94u	136	21	with	with	IN
cord-285180-32bxx94u	136	22	genespecific	genespecific	NNP
cord-285180-32bxx94u	136	23	primer	primer	NN
cord-285180-32bxx94u	136	24	sets	set	NNS
cord-285180-32bxx94u	136	25	as	as	IN
cord-285180-32bxx94u	136	26	described	describe	VBN
cord-285180-32bxx94u	136	27	previously	previously	RB
cord-285180-32bxx94u	136	28	(	(	-LRB-
cord-285180-32bxx94u	136	29	Sagong	Sagong	NNP
cord-285180-32bxx94u	136	30	and	and	CC
cord-285180-32bxx94u	136	31	Lee	Lee	NNP
cord-285180-32bxx94u	136	32	,	,	,
cord-285180-32bxx94u	136	33	2011	2011	CD
cord-285180-32bxx94u	136	34	)	)	-RRB-
cord-285180-32bxx94u	136	35	.	.	.
cord-285180-32bxx94u	137	1	The	the	DT
cord-285180-32bxx94u	137	2	primer	primer	NN
cord-285180-32bxx94u	137	3	sequences	sequence	NNS
cord-285180-32bxx94u	137	4	are	be	VBP
cord-285180-32bxx94u	137	5	available	available	JJ
cord-285180-32bxx94u	137	6	upon	upon	IN
cord-285180-32bxx94u	137	7	request	request	NN
cord-285180-32bxx94u	137	8	.	.	.
cord-285180-32bxx94u	138	1	The	the	DT
cord-285180-32bxx94u	138	2	RNA	RNA	NNP
cord-285180-32bxx94u	138	3	levels	level	NNS
cord-285180-32bxx94u	138	4	of	of	IN
cord-285180-32bxx94u	138	5	cellular	cellular	JJ
cord-285180-32bxx94u	138	6	genes	gene	NNS
cord-285180-32bxx94u	138	7	were	be	VBD
cord-285180-32bxx94u	138	8	normalized	normalize	VBN
cord-285180-32bxx94u	138	9	to	to	IN
cord-285180-32bxx94u	138	10	porcine	porcine	JJ
cord-285180-32bxx94u	138	11	␤	␤	.
cord-285180-32bxx94u	139	1	-actin	-actin	NFP
cord-285180-32bxx94u	140	1	mRNA	mRNA	NNP
cord-285180-32bxx94u	140	2	,	,	,
cord-285180-32bxx94u	140	3	and	and	CC
cord-285180-32bxx94u	140	4	relative	relative	JJ
cord-285180-32bxx94u	140	5	quantities	quantity	NNS
cord-285180-32bxx94u	140	6	(	(	-LRB-
cord-285180-32bxx94u	140	7	RQ	RQ	NNP
cord-285180-32bxx94u	140	8	)	)	-RRB-
cord-285180-32bxx94u	140	9	of	of	IN
cord-285180-32bxx94u	140	10	mRNA	mRNA	NNP
cord-285180-32bxx94u	140	11	accumulation	accumulation	NN
cord-285180-32bxx94u	140	12	were	be	VBD
cord-285180-32bxx94u	140	13	calculated	calculate	VBN
cord-285180-32bxx94u	140	14	using	use	VBG
cord-285180-32bxx94u	140	15	the	the	DT
cord-285180-32bxx94u	140	16	2	2	CD
cord-285180-32bxx94u	140	17	−	−	NNP
cord-285180-32bxx94u	140	18	Ct	Ct	NNP
cord-285180-32bxx94u	140	19	method	method	NN
cord-285180-32bxx94u	140	20	(	(	-LRB-
cord-285180-32bxx94u	140	21	Livak	Livak	NNP
cord-285180-32bxx94u	140	22	and	and	CC
cord-285180-32bxx94u	140	23	Schmittgen	Schmittgen	NNP
cord-285180-32bxx94u	140	24	,	,	,
cord-285180-32bxx94u	140	25	2001	2001	CD
cord-285180-32bxx94u	140	26	)	)	-RRB-
cord-285180-32bxx94u	140	27	.	.	.
cord-285180-32bxx94u	141	1	To	to	TO
cord-285180-32bxx94u	141	2	detect	detect	VB
cord-285180-32bxx94u	141	3	alterations	alteration	NNS
cord-285180-32bxx94u	141	4	of	of	IN
cord-285180-32bxx94u	141	5	cellular	cellular	JJ
cord-285180-32bxx94u	141	6	mRNA	mrna	NN
cord-285180-32bxx94u	141	7	levels	level	NNS
cord-285180-32bxx94u	141	8	in	in	IN
cord-285180-32bxx94u	141	9	the	the	DT
cord-285180-32bxx94u	141	10	presence	presence	NN
cord-285180-32bxx94u	141	11	of	of	IN
cord-285180-32bxx94u	141	12	the	the	DT
cord-285180-32bxx94u	141	13	PDCoV	pdcov	NN
cord-285180-32bxx94u	141	14	N	N	NNP
cord-285180-32bxx94u	141	15	protein	protein	NN
cord-285180-32bxx94u	141	16	,	,	,
cord-285180-32bxx94u	141	17	the	the	DT
cord-285180-32bxx94u	141	18	relative	relative	JJ
cord-285180-32bxx94u	141	19	fold	fold	JJ
cord-285180-32bxx94u	141	20	change	change	NN
cord-285180-32bxx94u	141	21	of	of	IN
cord-285180-32bxx94u	141	22	each	each	DT
cord-285180-32bxx94u	141	23	cellular	cellular	JJ
cord-285180-32bxx94u	141	24	gene	gene	NN
cord-285180-32bxx94u	141	25	was	be	VBD
cord-285180-32bxx94u	141	26	calculated	calculate	VBN
cord-285180-32bxx94u	141	27	in	in	IN
cord-285180-32bxx94u	141	28	accordance	accordance	NN
cord-285180-32bxx94u	141	29	with	with	IN
cord-285180-32bxx94u	141	30	the	the	DT
cord-285180-32bxx94u	141	31	comparison	comparison	NN
cord-285180-32bxx94u	141	32	of	of	IN
cord-285180-32bxx94u	141	33	PK	PK	NNP
cord-285180-32bxx94u	141	34	-	-	HYPH
cord-285180-32bxx94u	141	35	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	141	36	-	-	HYPH
cord-285180-32bxx94u	141	37	N	n	NN
cord-285180-32bxx94u	141	38	and	and	CC
cord-285180-32bxx94u	141	39	control	control	VB
cord-285180-32bxx94u	141	40	PK	PK	NNP
cord-285180-32bxx94u	141	41	-	-	HYPH
cord-285180-32bxx94u	141	42	Neo	Neo	NNP
cord-285180-32bxx94u	141	43	cells	cell	NNS
cord-285180-32bxx94u	141	44	.	.	.
cord-285180-32bxx94u	142	1	We	-PRON-	PRP
cord-285180-32bxx94u	142	2	used	use	VBD
cord-285180-32bxx94u	142	3	the	the	DT
cord-285180-32bxx94u	142	4	Student	Student	NNP
cord-285180-32bxx94u	142	5	's	's	POS
cord-285180-32bxx94u	142	6	t	t	NN
cord-285180-32bxx94u	142	7	-	-	HYPH
cord-285180-32bxx94u	142	8	test	test	NN
cord-285180-32bxx94u	142	9	for	for	IN
cord-285180-32bxx94u	142	10	all	all	DT
cord-285180-32bxx94u	142	11	statistical	statistical	JJ
cord-285180-32bxx94u	142	12	analyses	analysis	NNS
cord-285180-32bxx94u	142	13	,	,	,
cord-285180-32bxx94u	142	14	and	and	CC
cord-285180-32bxx94u	142	15	differences	difference	NNS
cord-285180-32bxx94u	142	16	with	with	IN
cord-285180-32bxx94u	142	17	p	p	NN
cord-285180-32bxx94u	142	18	-	-	HYPH
cord-285180-32bxx94u	142	19	values	value	NNS
cord-285180-32bxx94u	142	20	<	<	XX
cord-285180-32bxx94u	142	21	0.05	0.05	CD
cord-285180-32bxx94u	142	22	were	be	VBD
cord-285180-32bxx94u	142	23	considered	consider	VBN
cord-285180-32bxx94u	142	24	statistically	statistically	RB
cord-285180-32bxx94u	142	25	significant	significant	JJ
cord-285180-32bxx94u	142	26	.	.	.
cord-285180-32bxx94u	143	1	A	a	DT
cord-285180-32bxx94u	143	2	set	set	NN
cord-285180-32bxx94u	143	3	of	of	IN
cord-285180-32bxx94u	143	4	seven	seven	CD
cord-285180-32bxx94u	143	5	novel	novel	JJ
cord-285180-32bxx94u	143	6	mammalian	mammalian	JJ
cord-285180-32bxx94u	143	7	and	and	CC
cord-285180-32bxx94u	143	8	avian	avian	JJ
cord-285180-32bxx94u	143	9	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	143	10	was	be	VBD
cord-285180-32bxx94u	143	11	recently	recently	RB
cord-285180-32bxx94u	143	12	discovered	discover	VBN
cord-285180-32bxx94u	143	13	,	,	,
cord-285180-32bxx94u	143	14	including	include	VBG
cord-285180-32bxx94u	143	15	one	one	CD
cord-285180-32bxx94u	143	16	porcine	porcine	JJ
cord-285180-32bxx94u	143	17	coronavirus	coronavirus	NN
cord-285180-32bxx94u	143	18	,	,	,
cord-285180-32bxx94u	143	19	PDCoV	pdcov	ADD
cord-285180-32bxx94u	143	20	(	(	-LRB-
cord-285180-32bxx94u	143	21	Woo	woo	UH
cord-285180-32bxx94u	143	22	et	et	FW
cord-285180-32bxx94u	143	23	al	al	NNP
cord-285180-32bxx94u	143	24	.	.	NNP
cord-285180-32bxx94u	143	25	,	,	,
cord-285180-32bxx94u	143	26	2012	2012	CD
cord-285180-32bxx94u	143	27	)	)	-RRB-
cord-285180-32bxx94u	143	28	.	.	.
cord-285180-32bxx94u	144	1	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	144	2	is	be	VBZ
cord-285180-32bxx94u	144	3	the	the	DT
cord-285180-32bxx94u	144	4	fifth	fifth	JJ
cord-285180-32bxx94u	144	5	coronavirus	coronavirus	NN
cord-285180-32bxx94u	144	6	infecting	infect	VBG
cord-285180-32bxx94u	144	7	pigs	pig	NNS
cord-285180-32bxx94u	144	8	in	in	IN
cord-285180-32bxx94u	144	9	addition	addition	NN
cord-285180-32bxx94u	144	10	to	to	IN
cord-285180-32bxx94u	144	11	transmissible	transmissible	JJ
cord-285180-32bxx94u	144	12	gastroenteritis	gastroenteritis	NN
cord-285180-32bxx94u	144	13	virus	virus	NN
cord-285180-32bxx94u	144	14	,	,	,
cord-285180-32bxx94u	144	15	porcine	porcine	JJ
cord-285180-32bxx94u	144	16	respiratory	respiratory	JJ
cord-285180-32bxx94u	144	17	virus	virus	NN
cord-285180-32bxx94u	144	18	,	,	,
cord-285180-32bxx94u	144	19	porcine	porcine	JJ
cord-285180-32bxx94u	144	20	hemagglutinating	hemagglutinate	VBG
cord-285180-32bxx94u	144	21	encephalomyelitis	encephalomyelitis	NN
cord-285180-32bxx94u	144	22	virus	virus	NN
cord-285180-32bxx94u	144	23	,	,	,
cord-285180-32bxx94u	144	24	and	and	CC
cord-285180-32bxx94u	144	25	porcine	porcine	JJ
cord-285180-32bxx94u	144	26	epidemic	epidemic	NN
cord-285180-32bxx94u	144	27	diarrhea	diarrhea	NN
cord-285180-32bxx94u	144	28	virus	virus	NN
cord-285180-32bxx94u	144	29	(	(	-LRB-
cord-285180-32bxx94u	144	30	PEDV	PEDV	NNP
cord-285180-32bxx94u	144	31	)	)	-RRB-
cord-285180-32bxx94u	144	32	.	.	.
cord-285180-32bxx94u	145	1	To	to	IN
cord-285180-32bxx94u	145	2	date	date	NN
cord-285180-32bxx94u	145	3	,	,	,
cord-285180-32bxx94u	145	4	interactions	interaction	NNS
cord-285180-32bxx94u	145	5	between	between	IN
cord-285180-32bxx94u	145	6	this	this	DT
cord-285180-32bxx94u	145	7	novel	novel	JJ
cord-285180-32bxx94u	145	8	virus	virus	NN
cord-285180-32bxx94u	145	9	and	and	CC
cord-285180-32bxx94u	145	10	the	the	DT
cord-285180-32bxx94u	145	11	host	host	NN
cord-285180-32bxx94u	145	12	have	have	VBP
cord-285180-32bxx94u	145	13	not	not	RB
cord-285180-32bxx94u	145	14	been	be	VBN
cord-285180-32bxx94u	145	15	studied	study	VBN
cord-285180-32bxx94u	145	16	yet	yet	RB
cord-285180-32bxx94u	145	17	.	.	.
cord-285180-32bxx94u	146	1	Furthermore	furthermore	RB
cord-285180-32bxx94u	146	2	,	,	,
cord-285180-32bxx94u	146	3	alterations	alteration	NNS
cord-285180-32bxx94u	146	4	of	of	IN
cord-285180-32bxx94u	146	5	cellular	cellular	JJ
cord-285180-32bxx94u	146	6	protein	protein	NN
cord-285180-32bxx94u	146	7	expression	expression	NN
cord-285180-32bxx94u	146	8	in	in	IN
cord-285180-32bxx94u	146	9	response	response	NN
cord-285180-32bxx94u	146	10	to	to	IN
cord-285180-32bxx94u	146	11	PDCoV	pdcov	NN
cord-285180-32bxx94u	146	12	or	or	CC
cord-285180-32bxx94u	146	13	each	each	DT
cord-285180-32bxx94u	146	14	viral	viral	JJ
cord-285180-32bxx94u	146	15	protein	protein	NN
cord-285180-32bxx94u	146	16	upon	upon	IN
cord-285180-32bxx94u	146	17	infection	infection	NN
cord-285180-32bxx94u	146	18	currently	currently	RB
cord-285180-32bxx94u	146	19	remain	remain	VBP
cord-285180-32bxx94u	146	20	undetermined	undetermined	JJ
cord-285180-32bxx94u	146	21	.	.	.
cord-285180-32bxx94u	147	1	In	in	IN
cord-285180-32bxx94u	147	2	the	the	DT
cord-285180-32bxx94u	147	3	current	current	JJ
cord-285180-32bxx94u	147	4	study	study	NN
cord-285180-32bxx94u	147	5	,	,	,
cord-285180-32bxx94u	147	6	the	the	DT
cord-285180-32bxx94u	147	7	PDCoV	pdcov	NN
cord-285180-32bxx94u	147	8	N	N	NNP
cord-285180-32bxx94u	147	9	protein	protein	NN
cord-285180-32bxx94u	147	10	was	be	VBD
cord-285180-32bxx94u	147	11	chosen	choose	VBN
cord-285180-32bxx94u	147	12	in	in	IN
cord-285180-32bxx94u	147	13	the	the	DT
cord-285180-32bxx94u	147	14	current	current	JJ
cord-285180-32bxx94u	147	15	study	study	NN
cord-285180-32bxx94u	147	16	for	for	IN
cord-285180-32bxx94u	147	17	the	the	DT
cord-285180-32bxx94u	147	18	proteomic	proteomic	JJ
cord-285180-32bxx94u	147	19	analysis	analysis	NN
cord-285180-32bxx94u	147	20	to	to	TO
cord-285180-32bxx94u	147	21	evaluate	evaluate	VB
cord-285180-32bxx94u	147	22	specific	specific	JJ
cord-285180-32bxx94u	147	23	host	host	NN
cord-285180-32bxx94u	147	24	cellular	cellular	JJ
cord-285180-32bxx94u	147	25	responses	response	NNS
cord-285180-32bxx94u	147	26	,	,	,
cord-285180-32bxx94u	147	27	which	which	WDT
cord-285180-32bxx94u	147	28	is	be	VBZ
cord-285180-32bxx94u	147	29	not	not	RB
cord-285180-32bxx94u	147	30	only	only	RB
cord-285180-32bxx94u	147	31	the	the	DT
cord-285180-32bxx94u	147	32	most	most	RBS
cord-285180-32bxx94u	147	33	abundant	abundant	JJ
cord-285180-32bxx94u	147	34	viral	viral	JJ
cord-285180-32bxx94u	147	35	component	component	NN
cord-285180-32bxx94u	147	36	but	but	CC
cord-285180-32bxx94u	147	37	also	also	RB
cord-285180-32bxx94u	147	38	performs	perform	VBZ
cord-285180-32bxx94u	147	39	several	several	JJ
cord-285180-32bxx94u	147	40	biological	biological	JJ
cord-285180-32bxx94u	147	41	functions	function	NNS
cord-285180-32bxx94u	147	42	in	in	IN
cord-285180-32bxx94u	147	43	completing	complete	VBG
cord-285180-32bxx94u	147	44	viral	viral	JJ
cord-285180-32bxx94u	147	45	replication	replication	NN
cord-285180-32bxx94u	147	46	.	.	.
cord-285180-32bxx94u	148	1	For	for	IN
cord-285180-32bxx94u	148	2	this	this	DT
cord-285180-32bxx94u	148	3	purpose	purpose	NN
cord-285180-32bxx94u	148	4	,	,	,
cord-285180-32bxx94u	148	5	sublines	subline	NNS
cord-285180-32bxx94u	148	6	of	of	IN
cord-285180-32bxx94u	148	7	PK-15	PK-15	NNP
cord-285180-32bxx94u	148	8	cells	cell	NNS
cord-285180-32bxx94u	148	9	were	be	VBD
cord-285180-32bxx94u	148	10	established	establish	VBN
cord-285180-32bxx94u	148	11	to	to	TO
cord-285180-32bxx94u	148	12	stably	stably	RB
cord-285180-32bxx94u	148	13	express	express	VB
cord-285180-32bxx94u	148	14	recombinant	recombinant	JJ
cord-285180-32bxx94u	148	15	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	148	16	N	n	CD
cord-285180-32bxx94u	148	17	under	under	IN
cord-285180-32bxx94u	148	18	the	the	DT
cord-285180-32bxx94u	148	19	control	control	NN
cord-285180-32bxx94u	148	20	of	of	IN
cord-285180-32bxx94u	148	21	a	a	DT
cord-285180-32bxx94u	148	22	retroviral	retroviral	JJ
cord-285180-32bxx94u	148	23	longterminal	longterminal	JJ
cord-285180-32bxx94u	148	24	-	-	HYPH
cord-285180-32bxx94u	148	25	repeat	repeat	NN
cord-285180-32bxx94u	148	26	(	(	-LRB-
cord-285180-32bxx94u	148	27	LTR	ltr	NN
cord-285180-32bxx94u	148	28	)	)	-RRB-
cord-285180-32bxx94u	148	29	promoter	promoter	NN
cord-285180-32bxx94u	148	30	.	.	.
cord-285180-32bxx94u	149	1	Ten	ten	CD
cord-285180-32bxx94u	149	2	generated	generate	VBN
cord-285180-32bxx94u	149	3	cell	cell	NN
cord-285180-32bxx94u	149	4	clones	clone	NNS
cord-285180-32bxx94u	149	5	were	be	VBD
cord-285180-32bxx94u	149	6	initially	initially	RB
cord-285180-32bxx94u	149	7	collected	collect	VBN
cord-285180-32bxx94u	149	8	and	and	CC
cord-285180-32bxx94u	149	9	subjected	subject	VBN
cord-285180-32bxx94u	149	10	to	to	IN
cord-285180-32bxx94u	149	11	RT	RT	NNP
cord-285180-32bxx94u	149	12	-	-	HYPH
cord-285180-32bxx94u	149	13	PCR	PCR	NNP
cord-285180-32bxx94u	149	14	and	and	CC
cord-285180-32bxx94u	149	15	Western	western	JJ
cord-285180-32bxx94u	149	16	blotting	blotting	NN
cord-285180-32bxx94u	149	17	to	to	TO
cord-285180-32bxx94u	149	18	confirm	confirm	VB
cord-285180-32bxx94u	149	19	the	the	DT
cord-285180-32bxx94u	149	20	N	n	CD
cord-285180-32bxx94u	149	21	gene	gene	NN
cord-285180-32bxx94u	149	22	expression	expression	NN
cord-285180-32bxx94u	149	23	at	at	IN
cord-285180-32bxx94u	149	24	mRNA	mrna	NN
cord-285180-32bxx94u	149	25	and	and	CC
cord-285180-32bxx94u	149	26	protein	protein	NN
cord-285180-32bxx94u	149	27	levels	level	NNS
cord-285180-32bxx94u	149	28	,	,	,
cord-285180-32bxx94u	149	29	respectively	respectively	RB
cord-285180-32bxx94u	149	30	(	(	-LRB-
cord-285180-32bxx94u	149	31	data	datum	NNS
cord-285180-32bxx94u	149	32	not	not	RB
cord-285180-32bxx94u	149	33	shown	show	VBN
cord-285180-32bxx94u	149	34	)	)	-RRB-
cord-285180-32bxx94u	149	35	.	.	.
cord-285180-32bxx94u	150	1	According	accord	VBG
cord-285180-32bxx94u	150	2	to	to	IN
cord-285180-32bxx94u	150	3	the	the	DT
cord-285180-32bxx94u	150	4	results	result	NNS
cord-285180-32bxx94u	150	5	of	of	IN
cord-285180-32bxx94u	150	6	the	the	DT
cord-285180-32bxx94u	150	7	Western	western	JJ
cord-285180-32bxx94u	150	8	blot	blot	NN
cord-285180-32bxx94u	150	9	analysis	analysis	NN
cord-285180-32bxx94u	150	10	,	,	,
cord-285180-32bxx94u	150	11	one	one	CD
cord-285180-32bxx94u	150	12	PK	pk	NN
cord-285180-32bxx94u	150	13	-	-	HYPH
cord-285180-32bxx94u	150	14	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	150	15	-	-	HYPH
cord-285180-32bxx94u	150	16	N	n	CD
cord-285180-32bxx94u	150	17	cell	cell	NN
cord-285180-32bxx94u	150	18	clone	clone	NN
cord-285180-32bxx94u	150	19	that	that	WDT
cord-285180-32bxx94u	150	20	constitutively	constitutively	RB
cord-285180-32bxx94u	150	21	expressed	express	VBD
cord-285180-32bxx94u	150	22	the	the	DT
cord-285180-32bxx94u	150	23	highest	high	JJS
cord-285180-32bxx94u	150	24	levels	level	NNS
cord-285180-32bxx94u	150	25	of	of	IN
cord-285180-32bxx94u	150	26	N	N	NNP
cord-285180-32bxx94u	150	27	was	be	VBD
cord-285180-32bxx94u	150	28	selected	select	VBN
cord-285180-32bxx94u	150	29	for	for	IN
cord-285180-32bxx94u	150	30	subsequent	subsequent	JJ
cord-285180-32bxx94u	150	31	studies	study	NNS
cord-285180-32bxx94u	150	32	.	.	.
cord-285180-32bxx94u	151	1	To	to	TO
cord-285180-32bxx94u	151	2	characterize	characterize	VB
cord-285180-32bxx94u	151	3	PK	PK	NNP
cord-285180-32bxx94u	151	4	-	-	HYPH
cord-285180-32bxx94u	151	5	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	151	6	-	-	HYPH
cord-285180-32bxx94u	151	7	N	n	CD
cord-285180-32bxx94u	151	8	cells	cell	NNS
cord-285180-32bxx94u	151	9	,	,	,
cord-285180-32bxx94u	151	10	we	-PRON-	PRP
cord-285180-32bxx94u	151	11	examined	examine	VBD
cord-285180-32bxx94u	151	12	intracellular	intracellular	JJ
cord-285180-32bxx94u	151	13	expression	expression	NN
cord-285180-32bxx94u	151	14	levels	level	NNS
cord-285180-32bxx94u	151	15	of	of	IN
cord-285180-32bxx94u	151	16	N	n	CD
cord-285180-32bxx94u	151	17	by	by	IN
cord-285180-32bxx94u	151	18	IFA	IFA	NNP
cord-285180-32bxx94u	151	19	,	,	,
cord-285180-32bxx94u	151	20	FACS	FACS	NNP
cord-285180-32bxx94u	151	21	analysis	analysis	NN
cord-285180-32bxx94u	151	22	and	and	CC
cord-285180-32bxx94u	151	23	Western	western	JJ
cord-285180-32bxx94u	151	24	blotting	blotting	NN
cord-285180-32bxx94u	151	25	.	.	.
cord-285180-32bxx94u	152	1	As	as	IN
cord-285180-32bxx94u	152	2	shown	show	VBN
cord-285180-32bxx94u	152	3	in	in	IN
cord-285180-32bxx94u	152	4	Fig	Fig	NNP
cord-285180-32bxx94u	152	5	.	.	.
cord-285180-32bxx94u	153	1	1A	1a	LS
cord-285180-32bxx94u	153	2	,	,	,
cord-285180-32bxx94u	153	3	the	the	DT
cord-285180-32bxx94u	153	4	specific	specific	JJ
cord-285180-32bxx94u	153	5	cell	cell	NN
cord-285180-32bxx94u	153	6	staining	staining	NN
cord-285180-32bxx94u	153	7	was	be	VBD
cord-285180-32bxx94u	153	8	clearly	clearly	RB
cord-285180-32bxx94u	153	9	evident	evident	JJ
cord-285180-32bxx94u	153	10	when	when	WRB
cord-285180-32bxx94u	153	11	PK	PK	NNP
cord-285180-32bxx94u	153	12	-	-	HYPH
cord-285180-32bxx94u	153	13	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	153	14	-	-	HYPH
cord-285180-32bxx94u	153	15	N	n	CD
cord-285180-32bxx94u	153	16	cells	cell	NNS
cord-285180-32bxx94u	153	17	were	be	VBD
cord-285180-32bxx94u	153	18	reacted	react	VBN
cord-285180-32bxx94u	153	19	with	with	IN
cord-285180-32bxx94u	153	20	the	the	DT
cord-285180-32bxx94u	153	21	anti	anti	JJ
cord-285180-32bxx94u	153	22	-	-	JJ
cord-285180-32bxx94u	153	23	His	-PRON-	PRP$
cord-285180-32bxx94u	153	24	tag	tag	NN
cord-285180-32bxx94u	153	25	antibody	antibody	NN
cord-285180-32bxx94u	153	26	,	,	,
cord-285180-32bxx94u	153	27	confirming	confirm	VBG
cord-285180-32bxx94u	153	28	the	the	DT
cord-285180-32bxx94u	153	29	constant	constant	JJ
cord-285180-32bxx94u	153	30	high	high	JJ
cord-285180-32bxx94u	153	31	expression	expression	NN
cord-285180-32bxx94u	153	32	level	level	NN
cord-285180-32bxx94u	153	33	of	of	IN
cord-285180-32bxx94u	153	34	the	the	DT
cord-285180-32bxx94u	153	35	N	n	CD
cord-285180-32bxx94u	153	36	protein	protein	NN
cord-285180-32bxx94u	153	37	.	.	.
cord-285180-32bxx94u	154	1	Furthermore	furthermore	RB
cord-285180-32bxx94u	154	2	,	,	,
cord-285180-32bxx94u	154	3	the	the	DT
cord-285180-32bxx94u	154	4	majority	majority	NN
cord-285180-32bxx94u	154	5	of	of	IN
cord-285180-32bxx94u	154	6	the	the	DT
cord-285180-32bxx94u	154	7	cells	cell	NNS
cord-285180-32bxx94u	154	8	consistently	consistently	RB
cord-285180-32bxx94u	154	9	exhibited	exhibit	VBD
cord-285180-32bxx94u	154	10	specific	specific	JJ
cord-285180-32bxx94u	154	11	fluorescent	fluorescent	NN
cord-285180-32bxx94u	154	12	signals	signal	NNS
cord-285180-32bxx94u	154	13	,	,	,
cord-285180-32bxx94u	154	14	indicating	indicate	VBG
cord-285180-32bxx94u	154	15	a	a	DT
cord-285180-32bxx94u	154	16	homogenous	homogenous	JJ
cord-285180-32bxx94u	154	17	population	population	NN
cord-285180-32bxx94u	154	18	of	of	IN
cord-285180-32bxx94u	154	19	cells	cell	NNS
cord-285180-32bxx94u	154	20	in	in	IN
cord-285180-32bxx94u	154	21	terms	term	NNS
cord-285180-32bxx94u	154	22	of	of	IN
cord-285180-32bxx94u	154	23	N	n	CD
cord-285180-32bxx94u	154	24	expression	expression	NN
cord-285180-32bxx94u	154	25	(	(	-LRB-
cord-285180-32bxx94u	154	26	Fig	Fig	NNP
cord-285180-32bxx94u	154	27	.	.	.
cord-285180-32bxx94u	154	28	1B	1b	CD
cord-285180-32bxx94u	154	29	)	)	-RRB-
cord-285180-32bxx94u	154	30	.	.	.
cord-285180-32bxx94u	155	1	Time	time	NN
cord-285180-32bxx94u	155	2	-	-	HYPH
cord-285180-32bxx94u	155	3	course	course	NN
cord-285180-32bxx94u	155	4	Western	western	JJ
cord-285180-32bxx94u	155	5	blot	blot	NN
cord-285180-32bxx94u	155	6	analysis	analysis	NN
cord-285180-32bxx94u	155	7	revealed	reveal	VBD
cord-285180-32bxx94u	155	8	that	that	IN
cord-285180-32bxx94u	155	9	the	the	DT
cord-285180-32bxx94u	155	10	PK	PK	NNP
cord-285180-32bxx94u	155	11	-	-	HYPH
cord-285180-32bxx94u	155	12	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	155	13	-	-	HYPH
cord-285180-32bxx94u	155	14	N	n	CD
cord-285180-32bxx94u	155	15	cells	cell	NNS
cord-285180-32bxx94u	155	16	stably	stably	RB
cord-285180-32bxx94u	155	17	express	express	VBP
cord-285180-32bxx94u	155	18	and	and	CC
cord-285180-32bxx94u	155	19	accumulate	accumulate	VBP
cord-285180-32bxx94u	155	20	robust	robust	JJ
cord-285180-32bxx94u	155	21	levels	level	NNS
cord-285180-32bxx94u	155	22	of	of	IN
cord-285180-32bxx94u	155	23	a	a	DT
cord-285180-32bxx94u	155	24	∼45	∼45	JJ
cord-285180-32bxx94u	155	25	kDa	kDa	NNP
cord-285180-32bxx94u	155	26	recombinant	recombinant	JJ
cord-285180-32bxx94u	155	27	N	N	NNP
cord-285180-32bxx94u	155	28	protein	protein	NN
cord-285180-32bxx94u	155	29	,	,	,
cord-285180-32bxx94u	155	30	larger	large	JJR
cord-285180-32bxx94u	155	31	than	than	IN
cord-285180-32bxx94u	155	32	its	-PRON-	PRP$
cord-285180-32bxx94u	155	33	predicted	predict	VBN
cord-285180-32bxx94u	155	34	molecular	molecular	JJ
cord-285180-32bxx94u	155	35	weight	weight	NN
cord-285180-32bxx94u	155	36	of	of	IN
cord-285180-32bxx94u	155	37	approximately	approximately	RB
cord-285180-32bxx94u	155	38	38	38	CD
cord-285180-32bxx94u	155	39	kDa	kDa	NNS
cord-285180-32bxx94u	155	40	possibly	possibly	RB
cord-285180-32bxx94u	155	41	due	due	JJ
cord-285180-32bxx94u	155	42	to	to	IN
cord-285180-32bxx94u	155	43	post	post	JJ
cord-285180-32bxx94u	155	44	-	-	JJ
cord-285180-32bxx94u	155	45	translational	translational	JJ
cord-285180-32bxx94u	155	46	modifications	modification	NNS
cord-285180-32bxx94u	155	47	and	and	CC
cord-285180-32bxx94u	155	48	the	the	DT
cord-285180-32bxx94u	155	49	presence	presence	NN
cord-285180-32bxx94u	155	50	of	of	IN
cord-285180-32bxx94u	155	51	C	C	NNP
cord-285180-32bxx94u	155	52	-	-	HYPH
cord-285180-32bxx94u	155	53	terminal	terminal	NN
cord-285180-32bxx94u	155	54	myc	myc	NNP
cord-285180-32bxx94u	155	55	and	and	CC
cord-285180-32bxx94u	155	56	histidine	histidine	NN
cord-285180-32bxx94u	155	57	tags	tag	NNS
cord-285180-32bxx94u	155	58	(	(	-LRB-
cord-285180-32bxx94u	155	59	Fig	Fig	NNP
cord-285180-32bxx94u	155	60	.	.	.
cord-285180-32bxx94u	155	61	1C	1C	NNP
cord-285180-32bxx94u	155	62	)	)	-RRB-
cord-285180-32bxx94u	155	63	.	.	.
cord-285180-32bxx94u	156	1	In	in	IN
cord-285180-32bxx94u	156	2	addition	addition	NN
cord-285180-32bxx94u	156	3	,	,	,
cord-285180-32bxx94u	156	4	the	the	DT
cord-285180-32bxx94u	156	5	overall	overall	JJ
cord-285180-32bxx94u	156	6	growth	growth	NN
cord-285180-32bxx94u	156	7	kinetics	kinetic	NNS
cord-285180-32bxx94u	156	8	of	of	IN
cord-285180-32bxx94u	156	9	PDCoV	pdcov	NN
cord-285180-32bxx94u	156	10	N	n	CD
cord-285180-32bxx94u	156	11	gene	gene	NN
cord-285180-32bxx94u	156	12	-	-	HYPH
cord-285180-32bxx94u	156	13	expressing	express	VBG
cord-285180-32bxx94u	156	14	PK	PK	NNP
cord-285180-32bxx94u	156	15	cells	cell	NNS
cord-285180-32bxx94u	156	16	was	be	VBD
cord-285180-32bxx94u	156	17	found	find	VBN
cord-285180-32bxx94u	156	18	to	to	TO
cord-285180-32bxx94u	156	19	be	be	VB
cord-285180-32bxx94u	156	20	similar	similar	JJ
cord-285180-32bxx94u	156	21	to	to	IN
cord-285180-32bxx94u	156	22	that	that	DT
cord-285180-32bxx94u	156	23	of	of	IN
cord-285180-32bxx94u	156	24	the	the	DT
cord-285180-32bxx94u	156	25	parental	parental	JJ
cord-285180-32bxx94u	156	26	PK	PK	NNP
cord-285180-32bxx94u	156	27	-	-	HYPH
cord-285180-32bxx94u	156	28	Neo	Neo	NNP
cord-285180-32bxx94u	156	29	cells	cell	NNS
cord-285180-32bxx94u	156	30	,	,	,
cord-285180-32bxx94u	156	31	indicating	indicate	VBG
cord-285180-32bxx94u	156	32	that	that	IN
cord-285180-32bxx94u	156	33	the	the	DT
cord-285180-32bxx94u	156	34	PDCoV	pdcov	NN
cord-285180-32bxx94u	156	35	N	n	CD
cord-285180-32bxx94u	156	36	expression	expression	NN
cord-285180-32bxx94u	156	37	has	have	VBZ
cord-285180-32bxx94u	156	38	no	no	DT
cord-285180-32bxx94u	156	39	effect	effect	NN
cord-285180-32bxx94u	156	40	on	on	IN
cord-285180-32bxx94u	156	41	cell	cell	NN
cord-285180-32bxx94u	156	42	proliferation	proliferation	NN
cord-285180-32bxx94u	156	43	(	(	-LRB-
cord-285180-32bxx94u	156	44	Fig	Fig	NNP
cord-285180-32bxx94u	156	45	.	.	.
cord-285180-32bxx94u	156	46	1D	1d	CD
cord-285180-32bxx94u	156	47	)	)	-RRB-
cord-285180-32bxx94u	156	48	.	.	.
cord-285180-32bxx94u	157	1	Self	Self	NNP
cord-285180-32bxx94u	157	2	-	-	HYPH
cord-285180-32bxx94u	157	3	association	association	NNP
cord-285180-32bxx94u	157	4	of	of	IN
cord-285180-32bxx94u	157	5	the	the	DT
cord-285180-32bxx94u	157	6	N	N	NNP
cord-285180-32bxx94u	157	7	protein	protein	NN
cord-285180-32bxx94u	157	8	has	have	VBZ
cord-285180-32bxx94u	157	9	been	be	VBN
cord-285180-32bxx94u	157	10	observed	observe	VBN
cord-285180-32bxx94u	157	11	in	in	IN
cord-285180-32bxx94u	157	12	many	many	JJ
cord-285180-32bxx94u	157	13	viruses	virus	NNS
cord-285180-32bxx94u	157	14	,	,	,
cord-285180-32bxx94u	157	15	including	include	VBG
cord-285180-32bxx94u	157	16	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	157	17	,	,	,
cord-285180-32bxx94u	157	18	and	and	CC
cord-285180-32bxx94u	157	19	is	be	VBZ
cord-285180-32bxx94u	157	20	essential	essential	JJ
cord-285180-32bxx94u	157	21	for	for	IN
cord-285180-32bxx94u	157	22	assembly	assembly	NN
cord-285180-32bxx94u	157	23	of	of	IN
cord-285180-32bxx94u	157	24	the	the	DT
cord-285180-32bxx94u	157	25	viral	viral	JJ
cord-285180-32bxx94u	157	26	core	core	NN
cord-285180-32bxx94u	157	27	constructing	construct	VBG
cord-285180-32bxx94u	157	28	the	the	DT
cord-285180-32bxx94u	157	29	basic	basic	JJ
cord-285180-32bxx94u	157	30	architecture	architecture	NN
cord-285180-32bxx94u	157	31	of	of	IN
cord-285180-32bxx94u	157	32	viruses	virus	NNS
cord-285180-32bxx94u	157	33	.	.	.
cord-285180-32bxx94u	158	1	Sequence	sequence	NN
cord-285180-32bxx94u	158	2	analysis	analysis	NN
cord-285180-32bxx94u	158	3	of	of	IN
cord-285180-32bxx94u	158	4	the	the	DT
cord-285180-32bxx94u	158	5	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	158	6	N	N	NNP
cord-285180-32bxx94u	158	7	protein	protein	NN
cord-285180-32bxx94u	158	8	indicated	indicate	VBD
cord-285180-32bxx94u	158	9	that	that	IN
cord-285180-32bxx94u	158	10	it	-PRON-	PRP
cord-285180-32bxx94u	158	11	is	be	VBZ
cord-285180-32bxx94u	158	12	composed	compose	VBN
cord-285180-32bxx94u	158	13	of	of	IN
cord-285180-32bxx94u	158	14	342	342	CD
cord-285180-32bxx94u	158	15	amino	amino	JJ
cord-285180-32bxx94u	158	16	acids	acid	NNS
cord-285180-32bxx94u	158	17	residues	residue	NNS
cord-285180-32bxx94u	158	18	and	and	CC
cord-285180-32bxx94u	158	19	contains	contain	VBZ
cord-285180-32bxx94u	158	20	no	no	DT
cord-285180-32bxx94u	158	21	cysteine	cysteine	NN
cord-285180-32bxx94u	158	22	residues	residue	NNS
cord-285180-32bxx94u	158	23	.	.	.
cord-285180-32bxx94u	159	1	As	as	IN
cord-285180-32bxx94u	159	2	expected	expect	VBN
cord-285180-32bxx94u	159	3	,	,	,
cord-285180-32bxx94u	159	4	no	no	DT
cord-285180-32bxx94u	159	5	band	band	NN
cord-285180-32bxx94u	159	6	corresponding	correspond	VBG
cord-285180-32bxx94u	159	7	to	to	IN
cord-285180-32bxx94u	159	8	a	a	DT
cord-285180-32bxx94u	159	9	disulfide	disulfide	RB
cord-285180-32bxx94u	159	10	-	-	HYPH
cord-285180-32bxx94u	159	11	linked	link	VBN
cord-285180-32bxx94u	159	12	N	n	CD
cord-285180-32bxx94u	159	13	dimer	dimer	NN
cord-285180-32bxx94u	159	14	was	be	VBD
cord-285180-32bxx94u	159	15	detected	detect	VBN
cord-285180-32bxx94u	159	16	by	by	IN
cord-285180-32bxx94u	159	17	SDS	SDS	NNP
cord-285180-32bxx94u	159	18	-	-	HYPH
cord-285180-32bxx94u	159	19	PAGE	PAGE	NNP
cord-285180-32bxx94u	159	20	under	under	IN
cord-285180-32bxx94u	159	21	non	non	JJ
cord-285180-32bxx94u	159	22	-	-	JJ
cord-285180-32bxx94u	159	23	reducing	reducing	JJ
cord-285180-32bxx94u	159	24	conditions	condition	NNS
cord-285180-32bxx94u	159	25	(	(	-LRB-
cord-285180-32bxx94u	159	26	Fig	Fig	NNP
cord-285180-32bxx94u	159	27	.	.	.
cord-285180-32bxx94u	159	28	2A	2a	CD
cord-285180-32bxx94u	159	29	,	,	,
cord-285180-32bxx94u	159	30	 	 	_SP
cord-285180-32bxx94u	159	31	lane	lane	NNP
cord-285180-32bxx94u	159	32	4	4	CD
cord-285180-32bxx94u	159	33	)	)	-RRB-
cord-285180-32bxx94u	159	34	,	,	,
cord-285180-32bxx94u	159	35	indicating	indicate	VBG
cord-285180-32bxx94u	159	36	that	that	IN
cord-285180-32bxx94u	159	37	the	the	DT
cord-285180-32bxx94u	159	38	PDCoV	pdcov	NN
cord-285180-32bxx94u	159	39	N	n	CD
cord-285180-32bxx94u	159	40	protein	protein	NN
cord-285180-32bxx94u	159	41	does	do	VBZ
cord-285180-32bxx94u	159	42	not	not	RB
cord-285180-32bxx94u	159	43	undergo	undergo	VB
cord-285180-32bxx94u	159	44	cysteine	cysteine	NN
cord-285180-32bxx94u	159	45	-	-	HYPH
cord-285180-32bxx94u	159	46	linked	link	VBN
cord-285180-32bxx94u	159	47	homodimerization	homodimerization	NN
cord-285180-32bxx94u	159	48	.	.	.
cord-285180-32bxx94u	160	1	As	as	IN
cord-285180-32bxx94u	160	2	a	a	DT
cord-285180-32bxx94u	160	3	positive	positive	JJ
cord-285180-32bxx94u	160	4	control	control	NN
cord-285180-32bxx94u	160	5	,	,	,
cord-285180-32bxx94u	160	6	the	the	DT
cord-285180-32bxx94u	160	7	PRRSV	PRRSV	NNP
cord-285180-32bxx94u	160	8	N	N	NNP
cord-285180-32bxx94u	160	9	protein	protein	NN
cord-285180-32bxx94u	160	10	in	in	IN
cord-285180-32bxx94u	160	11	the	the	DT
cord-285180-32bxx94u	160	12	N	N	NNP
cord-285180-32bxx94u	160	13	-	-	HYPH
cord-285180-32bxx94u	160	14	expressing	express	VBG
cord-285180-32bxx94u	160	15	stable	stable	JJ
cord-285180-32bxx94u	160	16	PAM	PAM	NNP
cord-285180-32bxx94u	160	17	cells	cell	NNS
cord-285180-32bxx94u	160	18	was	be	VBD
cord-285180-32bxx94u	160	19	clearly	clearly	RB
cord-285180-32bxx94u	160	20	demonstrated	demonstrate	VBN
cord-285180-32bxx94u	160	21	to	to	TO
cord-285180-32bxx94u	160	22	form	form	VB
cord-285180-32bxx94u	160	23	35-kDa	35-kda	CD
cord-285180-32bxx94u	160	24	N	N	NNP
cord-285180-32bxx94u	160	25	-	-	HYPH
cord-285180-32bxx94u	160	26	N	N	NNP
cord-285180-32bxx94u	160	27	dimers	dimer	NNS
cord-285180-32bxx94u	160	28	under	under	IN
cord-285180-32bxx94u	160	29	the	the	DT
cord-285180-32bxx94u	160	30	same	same	JJ
cord-285180-32bxx94u	160	31	conditions	condition	NNS
cord-285180-32bxx94u	160	32	(	(	-LRB-
cord-285180-32bxx94u	160	33	Sagong	Sagong	NNP
cord-285180-32bxx94u	160	34	and	and	CC
cord-285180-32bxx94u	160	35	Lee	Lee	NNP
cord-285180-32bxx94u	160	36	,	,	,
cord-285180-32bxx94u	160	37	2010	2010	CD
cord-285180-32bxx94u	160	38	;	;	:
cord-285180-32bxx94u	160	39	 	 	_SP
cord-285180-32bxx94u	160	40	Fig	Fig	NNP
cord-285180-32bxx94u	160	41	.	.	.
cord-285180-32bxx94u	161	1	2A	2A	NNP
cord-285180-32bxx94u	161	2	,	,	,
cord-285180-32bxx94u	161	3	lane	lane	NN
cord-285180-32bxx94u	161	4	2	2	CD
cord-285180-32bxx94u	161	5	)	)	-RRB-
cord-285180-32bxx94u	161	6	.	.	.
cord-285180-32bxx94u	162	1	The	the	DT
cord-285180-32bxx94u	162	2	ability	ability	NN
cord-285180-32bxx94u	162	3	of	of	IN
cord-285180-32bxx94u	162	4	N	n	NN
cord-285180-32bxx94u	162	5	to	to	TO
cord-285180-32bxx94u	162	6	form	form	VB
cord-285180-32bxx94u	162	7	non	non	JJ
cord-285180-32bxx94u	162	8	-	-	JJ
cord-285180-32bxx94u	162	9	covalent	covalent	JJ
cord-285180-32bxx94u	162	10	dimers	dimer	NNS
cord-285180-32bxx94u	162	11	was	be	VBD
cord-285180-32bxx94u	162	12	further	further	RB
cord-285180-32bxx94u	162	13	investigated	investigate	VBN
cord-285180-32bxx94u	162	14	in	in	IN
cord-285180-32bxx94u	162	15	a	a	DT
cord-285180-32bxx94u	162	16	chemical	chemical	NN
cord-285180-32bxx94u	162	17	crosslinking	crosslinking	NN
cord-285180-32bxx94u	162	18	experiment	experiment	NN
cord-285180-32bxx94u	162	19	.	.	.
cord-285180-32bxx94u	163	1	As	as	IN
cord-285180-32bxx94u	163	2	shown	show	VBN
cord-285180-32bxx94u	163	3	in	in	IN
cord-285180-32bxx94u	163	4	Fig	Fig	NNP
cord-285180-32bxx94u	163	5	.	.	.
cord-285180-32bxx94u	163	6	2B	2b	CD
cord-285180-32bxx94u	163	7	,	,	,
cord-285180-32bxx94u	163	8	the	the	DT
cord-285180-32bxx94u	163	9	PRRSV	PRRSV	NNP
cord-285180-32bxx94u	163	10	N	N	NNP
cord-285180-32bxx94u	163	11	protein	protein	NN
cord-285180-32bxx94u	163	12	in	in	IN
cord-285180-32bxx94u	163	13	PAM	PAM	NNP
cord-285180-32bxx94u	163	14	-	-	HYPH
cord-285180-32bxx94u	163	15	pCD163-N	pCD163-N	NNP
cord-285180-32bxx94u	163	16	cells	cell	NNS
cord-285180-32bxx94u	163	17	formed	form	VBD
cord-285180-32bxx94u	163	18	a	a	DT
cord-285180-32bxx94u	163	19	number	number	NN
cord-285180-32bxx94u	163	20	of	of	IN
cord-285180-32bxx94u	163	21	higher	high	JJR
cord-285180-32bxx94u	163	22	-	-	HYPH
cord-285180-32bxx94u	163	23	order	order	NN
cord-285180-32bxx94u	163	24	oligomers	oligomer	NNS
cord-285180-32bxx94u	163	25	(	(	-LRB-
cord-285180-32bxx94u	163	26	lane	lane	NN
cord-285180-32bxx94u	163	27	1	1	CD
cord-285180-32bxx94u	163	28	)	)	-RRB-
cord-285180-32bxx94u	163	29	as	as	IN
cord-285180-32bxx94u	163	30	reported	report	VBN
cord-285180-32bxx94u	163	31	previously	previously	RB
cord-285180-32bxx94u	163	32	.	.	.
cord-285180-32bxx94u	164	1	When	when	WRB
cord-285180-32bxx94u	164	2	the	the	DT
cord-285180-32bxx94u	164	3	N	n	CD
cord-285180-32bxx94u	164	4	protein	protein	NN
cord-285180-32bxx94u	164	5	in	in	IN
cord-285180-32bxx94u	164	6	PK	PK	NNP
cord-285180-32bxx94u	164	7	-	-	HYPH
cord-285180-32bxx94u	164	8	PDCoV	pdcov	NN
cord-285180-32bxx94u	164	9	cells	cell	NNS
cord-285180-32bxx94u	164	10	was	be	VBD
cord-285180-32bxx94u	164	11	subjected	subject	VBN
cord-285180-32bxx94u	164	12	to	to	TO
cord-285180-32bxx94u	164	13	cross	cross	VB
cord-285180-32bxx94u	164	14	-	-	JJ
cord-285180-32bxx94u	164	15	linking	linking	JJ
cord-285180-32bxx94u	164	16	,	,	,
cord-285180-32bxx94u	164	17	numerous	numerous	JJ
cord-285180-32bxx94u	164	18	multimeric	multimeric	JJ
cord-285180-32bxx94u	164	19	forms	form	NNS
cord-285180-32bxx94u	164	20	of	of	IN
cord-285180-32bxx94u	164	21	the	the	DT
cord-285180-32bxx94u	164	22	N	N	NNP
cord-285180-32bxx94u	164	23	protein	protein	NN
cord-285180-32bxx94u	164	24	were	be	VBD
cord-285180-32bxx94u	164	25	identified	identify	VBN
cord-285180-32bxx94u	164	26	(	(	-LRB-
cord-285180-32bxx94u	164	27	lane	lane	NN
cord-285180-32bxx94u	164	28	2	2	CD
cord-285180-32bxx94u	164	29	)	)	-RRB-
cord-285180-32bxx94u	164	30	,	,	,
cord-285180-32bxx94u	164	31	indicating	indicate	VBG
cord-285180-32bxx94u	164	32	that	that	IN
cord-285180-32bxx94u	164	33	the	the	DT
cord-285180-32bxx94u	164	34	N	n	CD
cord-285180-32bxx94u	164	35	protein	protein	NN
cord-285180-32bxx94u	164	36	of	of	IN
cord-285180-32bxx94u	164	37	PDCoV	pdcov	NN
cord-285180-32bxx94u	164	38	exists	exist	NNS
cord-285180-32bxx94u	164	39	in	in	IN
cord-285180-32bxx94u	164	40	the	the	DT
cord-285180-32bxx94u	164	41	form	form	NN
cord-285180-32bxx94u	164	42	of	of	IN
cord-285180-32bxx94u	164	43	noncovalently	noncovalently	RB
cord-285180-32bxx94u	164	44	linked	link	VBN
cord-285180-32bxx94u	164	45	oligomers	oligomer	NNS
cord-285180-32bxx94u	164	46	that	that	WDT
cord-285180-32bxx94u	164	47	are	be	VBP
cord-285180-32bxx94u	164	48	used	use	VBN
cord-285180-32bxx94u	164	49	for	for	IN
cord-285180-32bxx94u	164	50	assembly	assembly	NN
cord-285180-32bxx94u	164	51	the	the	DT
cord-285180-32bxx94u	164	52	viral	viral	JJ
cord-285180-32bxx94u	164	53	capsid	capsid	NN
cord-285180-32bxx94u	164	54	.	.	.
cord-285180-32bxx94u	165	1	We	-PRON-	PRP
cord-285180-32bxx94u	165	2	next	next	RB
cord-285180-32bxx94u	165	3	determined	determine	VBD
cord-285180-32bxx94u	165	4	whether	whether	IN
cord-285180-32bxx94u	165	5	the	the	DT
cord-285180-32bxx94u	165	6	recombinant	recombinant	JJ
cord-285180-32bxx94u	165	7	N	N	NNP
cord-285180-32bxx94u	165	8	protein	protein	NN
cord-285180-32bxx94u	165	9	expressed	express	VBN
cord-285180-32bxx94u	165	10	in	in	IN
cord-285180-32bxx94u	165	11	PK	PK	NNP
cord-285180-32bxx94u	165	12	-	-	HYPH
cord-285180-32bxx94u	165	13	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	165	14	-	-	HYPH
cord-285180-32bxx94u	165	15	N	n	CD
cord-285180-32bxx94u	165	16	cells	cell	NNS
cord-285180-32bxx94u	165	17	is	be	VBZ
cord-285180-32bxx94u	165	18	subject	subject	JJ
cord-285180-32bxx94u	165	19	to	to	IN
cord-285180-32bxx94u	165	20	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	165	21	localization	localization	NN
cord-285180-32bxx94u	165	22	that	that	WDT
cord-285180-32bxx94u	165	23	is	be	VBZ
cord-285180-32bxx94u	165	24	known	know	VBN
cord-285180-32bxx94u	165	25	to	to	TO
cord-285180-32bxx94u	165	26	be	be	VB
cord-285180-32bxx94u	165	27	a	a	DT
cord-285180-32bxx94u	165	28	common	common	JJ
cord-285180-32bxx94u	165	29	feature	feature	NN
cord-285180-32bxx94u	165	30	of	of	IN
cord-285180-32bxx94u	165	31	coronaviral	coronaviral	JJ
cord-285180-32bxx94u	165	32	N	n	CD
cord-285180-32bxx94u	165	33	proteins	protein	NNS
cord-285180-32bxx94u	165	34	.	.	.
cord-285180-32bxx94u	166	1	The	the	DT
cord-285180-32bxx94u	166	2	staining	staining	NN
cord-285180-32bxx94u	166	3	pattern	pattern	NN
cord-285180-32bxx94u	166	4	in	in	IN
cord-285180-32bxx94u	166	5	PK	PK	NNP
cord-285180-32bxx94u	166	6	-	-	HYPH
cord-285180-32bxx94u	166	7	PDCoV	pdcov	NN
cord-285180-32bxx94u	166	8	cells	cell	NNS
cord-285180-32bxx94u	166	9	was	be	VBD
cord-285180-32bxx94u	166	10	found	find	VBN
cord-285180-32bxx94u	166	11	to	to	TO
cord-285180-32bxx94u	166	12	be	be	VB
cord-285180-32bxx94u	166	13	predominantly	predominantly	RB
cord-285180-32bxx94u	166	14	cytoplasmic	cytoplasmic	JJ
cord-285180-32bxx94u	166	15	and	and	CC
cord-285180-32bxx94u	166	16	nucleolic	nucleolic	JJ
cord-285180-32bxx94u	166	17	;	;	:
cord-285180-32bxx94u	166	18	this	this	DT
cord-285180-32bxx94u	166	19	pattern	pattern	NN
cord-285180-32bxx94u	166	20	persisted	persist	VBD
cord-285180-32bxx94u	166	21	for	for	IN
cord-285180-32bxx94u	166	22	up	up	IN
cord-285180-32bxx94u	166	23	to	to	TO
cord-285180-32bxx94u	166	24	60	60	CD
cord-285180-32bxx94u	166	25	h	h	NN
cord-285180-32bxx94u	166	26	after	after	IN
cord-285180-32bxx94u	166	27	seeding	seed	VBG
cord-285180-32bxx94u	166	28	(	(	-LRB-
cord-285180-32bxx94u	166	29	Fig	Fig	NNP
cord-285180-32bxx94u	166	30	.	.	.
cord-285180-32bxx94u	166	31	3A	3A	NNP
cord-285180-32bxx94u	166	32	)	)	-RRB-
cord-285180-32bxx94u	166	33	.	.	.
cord-285180-32bxx94u	167	1	Nearly	nearly	RB
cord-285180-32bxx94u	167	2	all	all	DT
cord-285180-32bxx94u	167	3	cells	cell	NNS
cord-285180-32bxx94u	167	4	expressing	express	VBG
cord-285180-32bxx94u	167	5	PDCoV	pdcov	RB
cord-285180-32bxx94u	167	6	N	n	CD
cord-285180-32bxx94u	167	7	showed	show	VBD
cord-285180-32bxx94u	167	8	distinct	distinct	JJ
cord-285180-32bxx94u	167	9	fluorescent	fluorescent	JJ
cord-285180-32bxx94u	167	10	signals	signal	NNS
cord-285180-32bxx94u	167	11	in	in	IN
cord-285180-32bxx94u	167	12	the	the	DT
cord-285180-32bxx94u	167	13	nucleolus	nucleolus	NN
cord-285180-32bxx94u	167	14	at	at	IN
cord-285180-32bxx94u	167	15	48	48	CD
cord-285180-32bxx94u	167	16	h	h	NN
cord-285180-32bxx94u	167	17	post	post	NN
cord-285180-32bxx94u	167	18	-	-	JJ
cord-285180-32bxx94u	167	19	seeding	seeding	JJ
cord-285180-32bxx94u	167	20	,	,	,
cord-285180-32bxx94u	167	21	and	and	CC
cord-285180-32bxx94u	167	22	thereafter	thereafter	RB
cord-285180-32bxx94u	167	23	,	,	,
cord-285180-32bxx94u	167	24	the	the	DT
cord-285180-32bxx94u	167	25	PDCoV	pdcov	NN
cord-285180-32bxx94u	167	26	N	N	NNP
cord-285180-32bxx94u	167	27	protein	protein	NN
cord-285180-32bxx94u	167	28	was	be	VBD
cord-285180-32bxx94u	167	29	localized	localize	VBN
cord-285180-32bxx94u	167	30	mainly	mainly	RB
cord-285180-32bxx94u	167	31	to	to	IN
cord-285180-32bxx94u	167	32	the	the	DT
cord-285180-32bxx94u	167	33	cytoplasm	cytoplasm	NN
cord-285180-32bxx94u	167	34	at	at	IN
cord-285180-32bxx94u	167	35	72	72	CD
cord-285180-32bxx94u	167	36	h	h	NN
cord-285180-32bxx94u	167	37	post	post	NN
cord-285180-32bxx94u	167	38	-	-	JJ
cord-285180-32bxx94u	167	39	seeding	seeding	JJ
cord-285180-32bxx94u	167	40	.	.	.
cord-285180-32bxx94u	168	1	The	the	DT
cord-285180-32bxx94u	168	2	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	168	3	localization	localization	NN
cord-285180-32bxx94u	168	4	of	of	IN
cord-285180-32bxx94u	168	5	PDCoV	pdcov	NN
cord-285180-32bxx94u	168	6	N	N	NNP
cord-285180-32bxx94u	168	7	was	be	VBD
cord-285180-32bxx94u	168	8	confirmed	confirm	VBN
cord-285180-32bxx94u	168	9	by	by	IN
cord-285180-32bxx94u	168	10	transient	transient	JJ
cord-285180-32bxx94u	168	11	transfection	transfection	NN
cord-285180-32bxx94u	168	12	of	of	IN
cord-285180-32bxx94u	168	13	BHK-21	BHK-21	NNP
cord-285180-32bxx94u	168	14	or	or	CC
cord-285180-32bxx94u	168	15	ST	ST	NNP
cord-285180-32bxx94u	168	16	cells	cell	NNS
cord-285180-32bxx94u	168	17	with	with	IN
cord-285180-32bxx94u	168	18	the	the	DT
cord-285180-32bxx94u	168	19	plasmid	plasmid	JJ
cord-285180-32bxx94u	168	20	pBud	pBud	NNP
cord-285180-32bxx94u	168	21	-	-	HYPH
cord-285180-32bxx94u	168	22	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	168	23	-	-	HYPH
cord-285180-32bxx94u	168	24	N	n	NN
cord-285180-32bxx94u	168	25	(	(	-LRB-
cord-285180-32bxx94u	168	26	Fig	Fig	NNP
cord-285180-32bxx94u	168	27	.	.	.
cord-285180-32bxx94u	168	28	3B	3B	NNP
cord-285180-32bxx94u	168	29	)	)	-RRB-
cord-285180-32bxx94u	168	30	.	.	.
cord-285180-32bxx94u	169	1	The	the	DT
cord-285180-32bxx94u	169	2	cell	cell	NN
cord-285180-32bxx94u	169	3	fractionation	fractionation	NN
cord-285180-32bxx94u	169	4	assay	assay	NN
cord-285180-32bxx94u	169	5	also	also	RB
cord-285180-32bxx94u	169	6	revealed	reveal	VBD
cord-285180-32bxx94u	169	7	the	the	DT
cord-285180-32bxx94u	169	8	presence	presence	NN
cord-285180-32bxx94u	169	9	of	of	IN
cord-285180-32bxx94u	169	10	the	the	DT
cord-285180-32bxx94u	169	11	N	N	NNP
cord-285180-32bxx94u	169	12	protein	protein	NN
cord-285180-32bxx94u	169	13	in	in	IN
cord-285180-32bxx94u	169	14	both	both	CC
cord-285180-32bxx94u	169	15	the	the	DT
cord-285180-32bxx94u	169	16	cytoplasmic	cytoplasmic	JJ
cord-285180-32bxx94u	169	17	and	and	CC
cord-285180-32bxx94u	169	18	nucleic	nucleic	JJ
cord-285180-32bxx94u	169	19	fractions	fraction	NNS
cord-285180-32bxx94u	169	20	(	(	-LRB-
cord-285180-32bxx94u	169	21	Fig	Fig	NNP
cord-285180-32bxx94u	169	22	.	.	.
cord-285180-32bxx94u	169	23	3C	3C	NNP
cord-285180-32bxx94u	169	24	)	)	-RRB-
cord-285180-32bxx94u	169	25	.	.	.
cord-285180-32bxx94u	170	1	These	these	DT
cord-285180-32bxx94u	170	2	observations	observation	NNS
cord-285180-32bxx94u	170	3	demonstrated	demonstrate	VBD
cord-285180-32bxx94u	170	4	that	that	IN
cord-285180-32bxx94u	170	5	,	,	,
cord-285180-32bxx94u	170	6	like	like	IN
cord-285180-32bxx94u	170	7	N	n	CD
cord-285180-32bxx94u	170	8	proteins	protein	NNS
cord-285180-32bxx94u	170	9	of	of	IN
cord-285180-32bxx94u	170	10	other	other	JJ
cord-285180-32bxx94u	170	11	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	170	12	,	,	,
cord-285180-32bxx94u	170	13	PDCoV	pdcov	NN
cord-285180-32bxx94u	170	14	N	n	NN
cord-285180-32bxx94u	170	15	protein	protein	NN
cord-285180-32bxx94u	170	16	is	be	VBZ
cord-285180-32bxx94u	170	17	mostly	mostly	RB
cord-285180-32bxx94u	170	18	distributed	distribute	VBN
cord-285180-32bxx94u	170	19	in	in	IN
cord-285180-32bxx94u	170	20	the	the	DT
cord-285180-32bxx94u	170	21	nucleolus	nucleolus	NN
cord-285180-32bxx94u	170	22	along	along	IN
cord-285180-32bxx94u	170	23	with	with	IN
cord-285180-32bxx94u	170	24	the	the	DT
cord-285180-32bxx94u	170	25	cytoplasm	cytoplasm	NN
cord-285180-32bxx94u	170	26	and	and	CC
cord-285180-32bxx94u	170	27	has	have	VBZ
cord-285180-32bxx94u	170	28	a	a	DT
cord-285180-32bxx94u	170	29	conserved	conserve	VBN
cord-285180-32bxx94u	170	30	subcellular	subcellular	JJ
cord-285180-32bxx94u	170	31	localization	localization	NN
cord-285180-32bxx94u	170	32	property	property	NN
cord-285180-32bxx94u	170	33	.	.	.
cord-285180-32bxx94u	170	34	 	 	_SP
cord-285180-32bxx94u	171	1	Cellular	cellular	JJ
cord-285180-32bxx94u	171	2	proteins	protein	NNS
cord-285180-32bxx94u	171	3	in	in	IN
cord-285180-32bxx94u	171	4	the	the	DT
cord-285180-32bxx94u	171	5	parental	parental	JJ
cord-285180-32bxx94u	171	6	PK	PK	NNP
cord-285180-32bxx94u	171	7	-	-	HYPH
cord-285180-32bxx94u	171	8	Neo	Neo	NNP
cord-285180-32bxx94u	171	9	cells	cell	NNS
cord-285180-32bxx94u	171	10	and	and	CC
cord-285180-32bxx94u	171	11	PK	pk	NN
cord-285180-32bxx94u	171	12	-	-	HYPH
cord-285180-32bxx94u	171	13	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	171	14	-	-	HYPH
cord-285180-32bxx94u	171	15	N	n	CD
cord-285180-32bxx94u	171	16	cells	cell	NNS
cord-285180-32bxx94u	171	17	were	be	VBD
cord-285180-32bxx94u	171	18	extracted	extract	VBN
cord-285180-32bxx94u	171	19	and	and	CC
cord-285180-32bxx94u	171	20	subjected	subject	VBN
cord-285180-32bxx94u	171	21	to	to	IN
cord-285180-32bxx94u	171	22	2DE	2de	CD
cord-285180-32bxx94u	171	23	analysis	analysis	NN
cord-285180-32bxx94u	171	24	to	to	TO
cord-285180-32bxx94u	171	25	compare	compare	VB
cord-285180-32bxx94u	171	26	the	the	DT
cord-285180-32bxx94u	171	27	host	host	NN
cord-285180-32bxx94u	171	28	protein	protein	NN
cord-285180-32bxx94u	171	29	expression	expression	NN
cord-285180-32bxx94u	171	30	profiles	profile	NNS
cord-285180-32bxx94u	171	31	.	.	.
cord-285180-32bxx94u	172	1	To	to	TO
cord-285180-32bxx94u	172	2	reduce	reduce	VB
cord-285180-32bxx94u	172	3	the	the	DT
cord-285180-32bxx94u	172	4	variability	variability	NN
cord-285180-32bxx94u	172	5	of	of	IN
cord-285180-32bxx94u	172	6	gel	gel	NN
cord-285180-32bxx94u	172	7	electrophoresis	electrophoresis	NN
cord-285180-32bxx94u	172	8	,	,	,
cord-285180-32bxx94u	172	9	three	three	CD
cord-285180-32bxx94u	172	10	independent	independent	JJ
cord-285180-32bxx94u	172	11	2DE	2de	CD
cord-285180-32bxx94u	172	12	analyses	analysis	NNS
cord-285180-32bxx94u	172	13	of	of	IN
cord-285180-32bxx94u	172	14	cellular	cellular	JJ
cord-285180-32bxx94u	172	15	extracts	extract	NNS
cord-285180-32bxx94u	172	16	from	from	IN
cord-285180-32bxx94u	172	17	control	control	NN
cord-285180-32bxx94u	172	18	or	or	CC
cord-285180-32bxx94u	172	19	N	n	CD
cord-285180-32bxx94u	172	20	gene	gene	NN
cord-285180-32bxx94u	172	21	-	-	HYPH
cord-285180-32bxx94u	172	22	expressing	express	VBG
cord-285180-32bxx94u	172	23	PK	PK	NNP
cord-285180-32bxx94u	172	24	cells	cell	NNS
cord-285180-32bxx94u	172	25	were	be	VBD
cord-285180-32bxx94u	172	26	performed	perform	VBN
cord-285180-32bxx94u	172	27	,	,	,
cord-285180-32bxx94u	172	28	and	and	CC
cord-285180-32bxx94u	172	29	spot	spot	VB
cord-285180-32bxx94u	172	30	intensity	intensity	NN
cord-285180-32bxx94u	172	31	data	datum	NNS
cord-285180-32bxx94u	172	32	from	from	IN
cord-285180-32bxx94u	172	33	triplicate	triplicate	JJ
cord-285180-32bxx94u	172	34	gels	gel	NNS
cord-285180-32bxx94u	172	35	were	be	VBD
cord-285180-32bxx94u	172	36	selected	select	VBN
cord-285180-32bxx94u	172	37	for	for	IN
cord-285180-32bxx94u	172	38	statistical	statistical	JJ
cord-285180-32bxx94u	172	39	analysis	analysis	NN
cord-285180-32bxx94u	172	40	.	.	.
cord-285180-32bxx94u	173	1	On	on	IN
cord-285180-32bxx94u	173	2	average	average	JJ
cord-285180-32bxx94u	173	3	,	,	,
cord-285180-32bxx94u	173	4	1090	1090	CD
cord-285180-32bxx94u	173	5	±	±	NNP
cord-285180-32bxx94u	173	6	63	63	CD
cord-285180-32bxx94u	173	7	protein	protein	NN
cord-285180-32bxx94u	173	8	spots	spot	NNS
cord-285180-32bxx94u	173	9	were	be	VBD
cord-285180-32bxx94u	173	10	resolved	resolve	VBN
cord-285180-32bxx94u	173	11	by	by	IN
cord-285180-32bxx94u	173	12	2DE	2DE	NNP
cord-285180-32bxx94u	173	13	within	within	IN
cord-285180-32bxx94u	173	14	a	a	DT
cord-285180-32bxx94u	173	15	pH	pH	NNP
cord-285180-32bxx94u	173	16	gradient	gradient	NN
cord-285180-32bxx94u	173	17	4	4	CD
cord-285180-32bxx94u	173	18	-	-	SYM
cord-285180-32bxx94u	173	19	10	10	CD
cord-285180-32bxx94u	173	20	and	and	CC
cord-285180-32bxx94u	173	21	were	be	VBD
cord-285180-32bxx94u	173	22	visualized	visualize	VBN
cord-285180-32bxx94u	173	23	using	use	VBG
cord-285180-32bxx94u	173	24	silver	silver	NN
cord-285180-32bxx94u	173	25	staining	staining	NN
cord-285180-32bxx94u	173	26	;	;	:
cord-285180-32bxx94u	173	27	the	the	DT
cord-285180-32bxx94u	173	28	molecular	molecular	JJ
cord-285180-32bxx94u	173	29	weights	weight	NNS
cord-285180-32bxx94u	173	30	of	of	IN
cord-285180-32bxx94u	173	31	the	the	DT
cord-285180-32bxx94u	173	32	spots	spot	NNS
cord-285180-32bxx94u	173	33	ranged	range	VBD
cord-285180-32bxx94u	173	34	from	from	IN
cord-285180-32bxx94u	173	35	10	10	CD
cord-285180-32bxx94u	173	36	to	to	IN
cord-285180-32bxx94u	173	37	200	200	CD
cord-285180-32bxx94u	173	38	kDa	kDa	NNS
cord-285180-32bxx94u	173	39	.	.	.
cord-285180-32bxx94u	174	1	These	these	DT
cord-285180-32bxx94u	174	2	spots	spot	NNS
cord-285180-32bxx94u	174	3	were	be	VBD
cord-285180-32bxx94u	174	4	used	use	VBN
cord-285180-32bxx94u	174	5	for	for	IN
cord-285180-32bxx94u	174	6	the	the	DT
cord-285180-32bxx94u	174	7	comparative	comparative	JJ
cord-285180-32bxx94u	174	8	analysis	analysis	NN
cord-285180-32bxx94u	174	9	.	.	.
cord-285180-32bxx94u	175	1	Fig	Fig	NNP
cord-285180-32bxx94u	175	2	.	.	.
cord-285180-32bxx94u	175	3	4A	4A	NNP
cord-285180-32bxx94u	175	4	shows	show	VBZ
cord-285180-32bxx94u	175	5	representative	representative	JJ
cord-285180-32bxx94u	175	6	images	image	NNS
cord-285180-32bxx94u	175	7	of	of	IN
cord-285180-32bxx94u	175	8	2DE	2de	CD
cord-285180-32bxx94u	175	9	gels	gel	NNS
cord-285180-32bxx94u	175	10	from	from	IN
cord-285180-32bxx94u	175	11	control	control	NN
cord-285180-32bxx94u	175	12	PK	PK	NNP
cord-285180-32bxx94u	175	13	cells	cell	NNS
cord-285180-32bxx94u	175	14	(	(	-LRB-
cord-285180-32bxx94u	175	15	upper	upper	JJ
cord-285180-32bxx94u	175	16	panel	panel	NN
cord-285180-32bxx94u	175	17	)	)	-RRB-
cord-285180-32bxx94u	175	18	and	and	CC
cord-285180-32bxx94u	175	19	N	n	CD
cord-285180-32bxx94u	175	20	gene	gene	NN
cord-285180-32bxx94u	175	21	-	-	HYPH
cord-285180-32bxx94u	175	22	expressing	express	VBG
cord-285180-32bxx94u	175	23	PK	PK	NNP
cord-285180-32bxx94u	175	24	cells	cell	NNS
cord-285180-32bxx94u	175	25	(	(	-LRB-
cord-285180-32bxx94u	175	26	middle	middle	JJ
cord-285180-32bxx94u	175	27	and	and	CC
cord-285180-32bxx94u	175	28	lower	low	JJR
cord-285180-32bxx94u	175	29	panels	panel	NNS
cord-285180-32bxx94u	175	30	)	)	-RRB-
cord-285180-32bxx94u	175	31	.	.	.
cord-285180-32bxx94u	176	1	A	a	DT
cord-285180-32bxx94u	176	2	total	total	NN
cord-285180-32bxx94u	176	3	of	of	IN
cord-285180-32bxx94u	176	4	43	43	CD
cord-285180-32bxx94u	176	5	protein	protein	NN
cord-285180-32bxx94u	176	6	spots	spot	NNS
cord-285180-32bxx94u	176	7	were	be	VBD
cord-285180-32bxx94u	176	8	initially	initially	RB
cord-285180-32bxx94u	176	9	found	find	VBN
cord-285180-32bxx94u	176	10	to	to	TO
cord-285180-32bxx94u	176	11	be	be	VB
cord-285180-32bxx94u	176	12	differentially	differentially	RB
cord-285180-32bxx94u	176	13	expressed	express	VBN
cord-285180-32bxx94u	176	14	in	in	IN
cord-285180-32bxx94u	176	15	PK	PK	NNP
cord-285180-32bxx94u	176	16	-	-	HYPH
cord-285180-32bxx94u	176	17	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	176	18	-	-	HYPH
cord-285180-32bxx94u	176	19	N	n	CD
cord-285180-32bxx94u	176	20	cells	cell	NNS
cord-285180-32bxx94u	176	21	when	when	WRB
cord-285180-32bxx94u	176	22	compared	compare	VBN
cord-285180-32bxx94u	176	23	with	with	IN
cord-285180-32bxx94u	176	24	control	control	NN
cord-285180-32bxx94u	176	25	PK	PK	NNP
cord-285180-32bxx94u	176	26	-	-	HYPH
cord-285180-32bxx94u	176	27	Neo	Neo	NNP
cord-285180-32bxx94u	176	28	cells	cell	NNS
cord-285180-32bxx94u	176	29	.	.	.
cord-285180-32bxx94u	177	1	On	on	IN
cord-285180-32bxx94u	177	2	the	the	DT
cord-285180-32bxx94u	177	3	basis	basis	NN
cord-285180-32bxx94u	177	4	of	of	IN
cord-285180-32bxx94u	177	5	the	the	DT
cord-285180-32bxx94u	177	6	statistical	statistical	JJ
cord-285180-32bxx94u	177	7	comparison	comparison	NN
cord-285180-32bxx94u	177	8	,	,	,
cord-285180-32bxx94u	177	9	only	only	RB
cord-285180-32bxx94u	177	10	those	those	DT
cord-285180-32bxx94u	177	11	spots	spot	NNS
cord-285180-32bxx94u	177	12	that	that	WDT
cord-285180-32bxx94u	177	13	consistently	consistently	RB
cord-285180-32bxx94u	177	14	showed	show	VBD
cord-285180-32bxx94u	177	15	alteration	alteration	NN
cord-285180-32bxx94u	177	16	in	in	IN
cord-285180-32bxx94u	177	17	expression	expression	NN
cord-285180-32bxx94u	177	18	levels	level	NNS
cord-285180-32bxx94u	177	19	between	between	IN
cord-285180-32bxx94u	177	20	PK	PK	NNP
cord-285180-32bxx94u	177	21	-	-	HYPH
cord-285180-32bxx94u	177	22	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	177	23	-	-	HYPH
cord-285180-32bxx94u	177	24	N	n	CD
cord-285180-32bxx94u	177	25	cells	cell	NNS
cord-285180-32bxx94u	177	26	and	and	CC
cord-285180-32bxx94u	177	27	the	the	DT
cord-285180-32bxx94u	177	28	control	control	NN
cord-285180-32bxx94u	177	29	cells	cell	NNS
cord-285180-32bxx94u	177	30	were	be	VBD
cord-285180-32bxx94u	177	31	chosen	choose	VBN
cord-285180-32bxx94u	177	32	for	for	IN
cord-285180-32bxx94u	177	33	further	further	JJ
cord-285180-32bxx94u	177	34	protein	protein	NN
cord-285180-32bxx94u	177	35	identification	identification	NN
cord-285180-32bxx94u	177	36	.	.	.
cord-285180-32bxx94u	178	1	To	to	TO
cord-285180-32bxx94u	178	2	identify	identify	VB
cord-285180-32bxx94u	178	3	the	the	DT
cord-285180-32bxx94u	178	4	differentially	differentially	RB
cord-285180-32bxx94u	178	5	expressed	express	VBN
cord-285180-32bxx94u	178	6	cellular	cellular	JJ
cord-285180-32bxx94u	178	7	protein	protein	NN
cord-285180-32bxx94u	178	8	spots	spot	NNS
cord-285180-32bxx94u	178	9	in	in	IN
cord-285180-32bxx94u	178	10	PK	PK	NNP
cord-285180-32bxx94u	178	11	-	-	HYPH
cord-285180-32bxx94u	178	12	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	178	13	-	-	HYPH
cord-285180-32bxx94u	178	14	N	n	CD
cord-285180-32bxx94u	178	15	cells	cell	NNS
cord-285180-32bxx94u	178	16	at	at	IN
cord-285180-32bxx94u	178	17	different	different	JJ
cord-285180-32bxx94u	178	18	time	time	NN
cord-285180-32bxx94u	178	19	points	point	NNS
cord-285180-32bxx94u	178	20	,	,	,
cord-285180-32bxx94u	178	21	10	10	CD
cord-285180-32bxx94u	178	22	protein	protein	NN
cord-285180-32bxx94u	178	23	spots	spot	NNS
cord-285180-32bxx94u	178	24	with	with	IN
cord-285180-32bxx94u	178	25	a	a	DT
cord-285180-32bxx94u	178	26	statistically	statistically	RB
cord-285180-32bxx94u	178	27	significant	significant	JJ
cord-285180-32bxx94u	178	28	alteration	alteration	NN
cord-285180-32bxx94u	178	29	,	,	,
cord-285180-32bxx94u	178	30	including	include	VBG
cord-285180-32bxx94u	178	31	8	8	CD
cord-285180-32bxx94u	178	32	up	up	RB
cord-285180-32bxx94u	178	33	-	-	HYPH
cord-285180-32bxx94u	178	34	regulated	regulate	VBN
cord-285180-32bxx94u	178	35	and	and	CC
cord-285180-32bxx94u	178	36	2	2	CD
cord-285180-32bxx94u	178	37	down	down	RB
cord-285180-32bxx94u	178	38	-	-	HYPH
cord-285180-32bxx94u	178	39	regulated	regulate	VBN
cord-285180-32bxx94u	178	40	protein	protein	NN
cord-285180-32bxx94u	178	41	spots	spot	NNS
cord-285180-32bxx94u	178	42	(	(	-LRB-
cord-285180-32bxx94u	178	43	Fig	Fig	NNP
cord-285180-32bxx94u	178	44	.	.	.
cord-285180-32bxx94u	178	45	4B	4b	LS
cord-285180-32bxx94u	178	46	)	)	-RRB-
cord-285180-32bxx94u	178	47	,	,	,
cord-285180-32bxx94u	178	48	were	be	VBD
cord-285180-32bxx94u	178	49	selected	select	VBN
cord-285180-32bxx94u	178	50	and	and	CC
cord-285180-32bxx94u	178	51	manually	manually	RB
cord-285180-32bxx94u	178	52	excised	excise	VBN
cord-285180-32bxx94u	178	53	from	from	IN
cord-285180-32bxx94u	178	54	the	the	DT
cord-285180-32bxx94u	178	55	stained	stained	JJ
cord-285180-32bxx94u	178	56	gels	gel	NNS
cord-285180-32bxx94u	178	57	.	.	.
cord-285180-32bxx94u	179	1	Subsequently	subsequently	RB
cord-285180-32bxx94u	179	2	,	,	,
cord-285180-32bxx94u	179	3	the	the	DT
cord-285180-32bxx94u	179	4	trypsin	trypsin	NN
cord-285180-32bxx94u	179	5	-	-	HYPH
cord-285180-32bxx94u	179	6	digested	digest	VBN
cord-285180-32bxx94u	179	7	spots	spot	NNS
cord-285180-32bxx94u	179	8	were	be	VBD
cord-285180-32bxx94u	179	9	subjected	subject	VBN
cord-285180-32bxx94u	179	10	to	to	IN
cord-285180-32bxx94u	179	11	MALDI	MALDI	NNP
cord-285180-32bxx94u	179	12	-	-	HYPH
cord-285180-32bxx94u	179	13	TOF	TOF	NNP
cord-285180-32bxx94u	179	14	analysis	analysis	NN
cord-285180-32bxx94u	179	15	.	.	.
cord-285180-32bxx94u	180	1	With	with	IN
cord-285180-32bxx94u	180	2	combined	combine	VBN
cord-285180-32bxx94u	180	3	PMF	PMF	NNP
cord-285180-32bxx94u	180	4	and	and	CC
cord-285180-32bxx94u	180	5	database	database	NN
cord-285180-32bxx94u	180	6	searching	searching	NN
cord-285180-32bxx94u	180	7	,	,	,
cord-285180-32bxx94u	180	8	identity	identity	NN
cord-285180-32bxx94u	180	9	of	of	IN
cord-285180-32bxx94u	180	10	all	all	DT
cord-285180-32bxx94u	180	11	10	10	CD
cord-285180-32bxx94u	180	12	proteins	protein	NNS
cord-285180-32bxx94u	180	13	was	be	VBD
cord-285180-32bxx94u	180	14	successfully	successfully	RB
cord-285180-32bxx94u	180	15	determined	determine	VBN
cord-285180-32bxx94u	180	16	.	.	.
cord-285180-32bxx94u	181	1	Information	information	NN
cord-285180-32bxx94u	181	2	on	on	IN
cord-285180-32bxx94u	181	3	all	all	PDT
cord-285180-32bxx94u	181	4	these	these	DT
cord-285180-32bxx94u	181	5	proteins	protein	NNS
cord-285180-32bxx94u	181	6	in	in	IN
cord-285180-32bxx94u	181	7	PK	PK	NNP
cord-285180-32bxx94u	181	8	-	-	HYPH
cord-285180-32bxx94u	181	9	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	181	10	-	-	HYPH
cord-285180-32bxx94u	181	11	N	n	CD
cord-285180-32bxx94u	181	12	cells	cell	NNS
cord-285180-32bxx94u	181	13	,	,	,
cord-285180-32bxx94u	181	14	with	with	IN
cord-285180-32bxx94u	181	15	their	-PRON-	PRP$
cord-285180-32bxx94u	181	16	protein	protein	NN
cord-285180-32bxx94u	181	17	scores	score	NNS
cord-285180-32bxx94u	181	18	and	and	CC
cord-285180-32bxx94u	181	19	sequence	sequence	NN
cord-285180-32bxx94u	181	20	coverage	coverage	NN
cord-285180-32bxx94u	181	21	,	,	,
cord-285180-32bxx94u	181	22	is	be	VBZ
cord-285180-32bxx94u	181	23	summarized	summarize	VBN
cord-285180-32bxx94u	181	24	in	in	IN
cord-285180-32bxx94u	181	25	Table	Table	NNP
cord-285180-32bxx94u	181	26	1	1	CD
cord-285180-32bxx94u	181	27	.	.	.
cord-285180-32bxx94u	182	1	To	to	TO
cord-285180-32bxx94u	182	2	better	well	RBR
cord-285180-32bxx94u	182	3	understand	understand	VB
cord-285180-32bxx94u	182	4	the	the	DT
cord-285180-32bxx94u	182	5	implications	implication	NNS
cord-285180-32bxx94u	182	6	of	of	IN
cord-285180-32bxx94u	182	7	the	the	DT
cord-285180-32bxx94u	182	8	cellular	cellular	JJ
cord-285180-32bxx94u	182	9	responses	response	NNS
cord-285180-32bxx94u	182	10	to	to	IN
cord-285180-32bxx94u	182	11	the	the	DT
cord-285180-32bxx94u	182	12	PDCoV	pdcov	NN
cord-285180-32bxx94u	182	13	N	n	CD
cord-285180-32bxx94u	182	14	protein	protein	NN
cord-285180-32bxx94u	182	15	,	,	,
cord-285180-32bxx94u	182	16	we	-PRON-	PRP
cord-285180-32bxx94u	182	17	further	further	RB
cord-285180-32bxx94u	182	18	(	(	-LRB-
cord-285180-32bxx94u	182	19	C	C	NNP
cord-285180-32bxx94u	182	20	)	)	-RRB-
cord-285180-32bxx94u	182	21	Nuclear	nuclear	JJ
cord-285180-32bxx94u	182	22	and	and	CC
cord-285180-32bxx94u	182	23	cytoplasmic	cytoplasmic	JJ
cord-285180-32bxx94u	182	24	fractionation	fractionation	NN
cord-285180-32bxx94u	182	25	of	of	IN
cord-285180-32bxx94u	182	26	PK	PK	NNP
cord-285180-32bxx94u	182	27	cells	cell	NNS
cord-285180-32bxx94u	182	28	expressing	express	VBG
cord-285180-32bxx94u	182	29	PDCoV	pdcov	CD
cord-285180-32bxx94u	182	30	N.	n.	NN
cord-285180-32bxx94u	183	1	Each	each	DT
cord-285180-32bxx94u	183	2	nuclear	nuclear	JJ
cord-285180-32bxx94u	183	3	and	and	CC
cord-285180-32bxx94u	183	4	cytosolic	cytosolic	JJ
cord-285180-32bxx94u	183	5	fraction	fraction	NN
cord-285180-32bxx94u	183	6	was	be	VBD
cord-285180-32bxx94u	183	7	prepared	prepare	VBN
cord-285180-32bxx94u	183	8	from	from	IN
cord-285180-32bxx94u	183	9	PK	PK	NNP
cord-285180-32bxx94u	183	10	-	-	HYPH
cord-285180-32bxx94u	183	11	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	183	12	-	-	HYPH
cord-285180-32bxx94u	183	13	N	n	CD
cord-285180-32bxx94u	183	14	cells	cell	NNS
cord-285180-32bxx94u	183	15	at	at	IN
cord-285180-32bxx94u	183	16	indicated	indicate	VBN
cord-285180-32bxx94u	183	17	time	time	NN
cord-285180-32bxx94u	183	18	points	point	NNS
cord-285180-32bxx94u	183	19	post	post	NN
cord-285180-32bxx94u	183	20	-	-	JJ
cord-285180-32bxx94u	183	21	seeding	seeding	JJ
cord-285180-32bxx94u	183	22	and	and	CC
cord-285180-32bxx94u	183	23	subjected	subject	VBN
cord-285180-32bxx94u	183	24	to	to	IN
cord-285180-32bxx94u	183	25	Western	western	JJ
cord-285180-32bxx94u	183	26	blot	blot	NN
cord-285180-32bxx94u	183	27	analysis	analysis	NN
cord-285180-32bxx94u	183	28	with	with	IN
cord-285180-32bxx94u	183	29	the	the	DT
cord-285180-32bxx94u	183	30	antibody	antibody	NN
cord-285180-32bxx94u	183	31	specific	specific	JJ
cord-285180-32bxx94u	183	32	for	for	IN
cord-285180-32bxx94u	183	33	His	-PRON-	PRP$
cord-285180-32bxx94u	183	34	-	-	HYPH
cord-285180-32bxx94u	183	35	tag	tag	NN
cord-285180-32bxx94u	183	36	(	(	-LRB-
cord-285180-32bxx94u	183	37	top	top	JJ
cord-285180-32bxx94u	183	38	panel	panel	NN
cord-285180-32bxx94u	183	39	)	)	-RRB-
cord-285180-32bxx94u	183	40	,	,	,
cord-285180-32bxx94u	183	41	Sp1	Sp1	NNP
cord-285180-32bxx94u	183	42	as	as	IN
cord-285180-32bxx94u	183	43	a	a	DT
cord-285180-32bxx94u	183	44	nuclear	nuclear	JJ
cord-285180-32bxx94u	183	45	protein	protein	NN
cord-285180-32bxx94u	183	46	marker	marker	NN
cord-285180-32bxx94u	183	47	(	(	-LRB-
cord-285180-32bxx94u	183	48	second	second	JJ
cord-285180-32bxx94u	183	49	panel	panel	NN
cord-285180-32bxx94u	183	50	)	)	-RRB-
cord-285180-32bxx94u	183	51	,	,	,
cord-285180-32bxx94u	183	52	or	or	CC
cord-285180-32bxx94u	183	53	␣	␣	RB
cord-285180-32bxx94u	183	54	-tubulin	-tubulin	SYM
cord-285180-32bxx94u	183	55	as	as	IN
cord-285180-32bxx94u	183	56	a	a	DT
cord-285180-32bxx94u	183	57	cytosolic	cytosolic	JJ
cord-285180-32bxx94u	183	58	protein	protein	NN
cord-285180-32bxx94u	183	59	marker	marker	NN
cord-285180-32bxx94u	183	60	(	(	-LRB-
cord-285180-32bxx94u	183	61	third	third	JJ
cord-285180-32bxx94u	183	62	panel	panel	NN
cord-285180-32bxx94u	183	63	)	)	-RRB-
cord-285180-32bxx94u	183	64	.	.	.
cord-285180-32bxx94u	184	1	All	all	DT
cord-285180-32bxx94u	184	2	blots	blot	NNS
cord-285180-32bxx94u	184	3	were	be	VBD
cord-285180-32bxx94u	184	4	also	also	RB
cord-285180-32bxx94u	184	5	reacted	react	VBN
cord-285180-32bxx94u	184	6	with	with	IN
cord-285180-32bxx94u	184	7	␤	␤	DT
cord-285180-32bxx94u	184	8	-actin	-actin	NNP
cord-285180-32bxx94u	184	9	antibody	antibody	NN
cord-285180-32bxx94u	184	10	to	to	TO
cord-285180-32bxx94u	184	11	verify	verify	VB
cord-285180-32bxx94u	184	12	equal	equal	JJ
cord-285180-32bxx94u	184	13	protein	protein	NN
cord-285180-32bxx94u	184	14	loading	loading	NN
cord-285180-32bxx94u	184	15	(	(	-LRB-
cord-285180-32bxx94u	184	16	bottom	bottom	JJ
cord-285180-32bxx94u	184	17	panel	panel	NN
cord-285180-32bxx94u	184	18	)	)	-RRB-
cord-285180-32bxx94u	184	19	.	.	.
cord-285180-32bxx94u	185	1	categorized	categorize	VBD
cord-285180-32bxx94u	185	2	the	the	DT
cord-285180-32bxx94u	185	3	identified	identify	VBN
cord-285180-32bxx94u	185	4	proteins	protein	NNS
cord-285180-32bxx94u	185	5	by	by	IN
cord-285180-32bxx94u	185	6	biological	biological	JJ
cord-285180-32bxx94u	185	7	processes	process	NNS
cord-285180-32bxx94u	185	8	according	accord	VBG
cord-285180-32bxx94u	185	9	to	to	IN
cord-285180-32bxx94u	185	10	the	the	DT
cord-285180-32bxx94u	185	11	Gene	Gene	NNP
cord-285180-32bxx94u	185	12	Ontology	Ontology	NNP
cord-285180-32bxx94u	185	13	database	database	NN
cord-285180-32bxx94u	185	14	as	as	IN
cord-285180-32bxx94u	185	15	described	describe	VBN
cord-285180-32bxx94u	185	16	previously	previously	RB
cord-285180-32bxx94u	185	17	(	(	-LRB-
cord-285180-32bxx94u	185	18	Zhang	Zhang	NNP
cord-285180-32bxx94u	185	19	et	et	NNP
cord-285180-32bxx94u	185	20	al	al	NNP
cord-285180-32bxx94u	185	21	.	.	NNP
cord-285180-32bxx94u	185	22	,	,	,
cord-285180-32bxx94u	185	23	2009	2009	CD
cord-285180-32bxx94u	185	24	)	)	-RRB-
cord-285180-32bxx94u	185	25	.	.	.
cord-285180-32bxx94u	186	1	These	these	DT
cord-285180-32bxx94u	186	2	proteins	protein	NNS
cord-285180-32bxx94u	186	3	showing	show	VBG
cord-285180-32bxx94u	186	4	altered	altered	JJ
cord-285180-32bxx94u	186	5	expression	expression	NN
cord-285180-32bxx94u	186	6	were	be	VBD
cord-285180-32bxx94u	186	7	associated	associate	VBN
cord-285180-32bxx94u	186	8	with	with	IN
cord-285180-32bxx94u	186	9	various	various	JJ
cord-285180-32bxx94u	186	10	cellular	cellular	JJ
cord-285180-32bxx94u	186	11	functions	function	NNS
cord-285180-32bxx94u	186	12	including	include	VBG
cord-285180-32bxx94u	186	13	intracellular	intracellular	JJ
cord-285180-32bxx94u	186	14	transport	transport	NN
cord-285180-32bxx94u	186	15	,	,	,
cord-285180-32bxx94u	186	16	metabolic	metabolic	JJ
cord-285180-32bxx94u	186	17	processes	process	NNS
cord-285180-32bxx94u	186	18	,	,	,
cord-285180-32bxx94u	186	19	gene	gene	NN
cord-285180-32bxx94u	186	20	regulation	regulation	NN
cord-285180-32bxx94u	186	21	,	,	,
cord-285180-32bxx94u	186	22	the	the	DT
cord-285180-32bxx94u	186	23	stress	stress	NN
cord-285180-32bxx94u	186	24	response	response	NN
cord-285180-32bxx94u	186	25	,	,	,
cord-285180-32bxx94u	186	26	protein	protein	NN
cord-285180-32bxx94u	186	27	synthesis	synthesis	NN
cord-285180-32bxx94u	186	28	,	,	,
cord-285180-32bxx94u	186	29	cytoskeleton	cytoskeleton	NN
cord-285180-32bxx94u	186	30	networks	network	NNS
cord-285180-32bxx94u	186	31	,	,	,
cord-285180-32bxx94u	186	32	and	and	CC
cord-285180-32bxx94u	186	33	cell	cell	NN
cord-285180-32bxx94u	186	34	division	division	NN
cord-285180-32bxx94u	186	35	.	.	.
cord-285180-32bxx94u	187	1	Since	since	IN
cord-285180-32bxx94u	187	2	changes	change	NNS
cord-285180-32bxx94u	187	3	in	in	IN
cord-285180-32bxx94u	187	4	cellular	cellular	JJ
cord-285180-32bxx94u	187	5	protein	protein	NN
cord-285180-32bxx94u	187	6	expression	expression	NN
cord-285180-32bxx94u	187	7	may	may	MD
cord-285180-32bxx94u	187	8	be	be	VB
cord-285180-32bxx94u	187	9	attributed	attribute	VBN
cord-285180-32bxx94u	187	10	to	to	IN
cord-285180-32bxx94u	187	11	alterations	alteration	NNS
cord-285180-32bxx94u	187	12	in	in	IN
cord-285180-32bxx94u	187	13	the	the	DT
cord-285180-32bxx94u	187	14	corresponding	correspond	VBG
cord-285180-32bxx94u	187	15	mRNA	mRNA	NNP
cord-285180-32bxx94u	187	16	levels	level	NNS
cord-285180-32bxx94u	187	17	,	,	,
cord-285180-32bxx94u	187	18	transcriptional	transcriptional	JJ
cord-285180-32bxx94u	187	19	changes	change	NNS
cord-285180-32bxx94u	187	20	for	for	IN
cord-285180-32bxx94u	187	21	all	all	PDT
cord-285180-32bxx94u	187	22	the	the	DT
cord-285180-32bxx94u	187	23	identified	identify	VBN
cord-285180-32bxx94u	187	24	proteins	protein	NNS
cord-285180-32bxx94u	187	25	were	be	VBD
cord-285180-32bxx94u	187	26	tested	test	VBN
cord-285180-32bxx94u	187	27	by	by	IN
cord-285180-32bxx94u	187	28	real	real	JJ
cord-285180-32bxx94u	187	29	-	-	HYPH
cord-285180-32bxx94u	187	30	time	time	NN
cord-285180-32bxx94u	187	31	RT	RT	NNP
cord-285180-32bxx94u	187	32	-	-	HYPH
cord-285180-32bxx94u	187	33	PCR	PCR	NNP
cord-285180-32bxx94u	187	34	to	to	TO
cord-285180-32bxx94u	187	35	confirm	confirm	VB
cord-285180-32bxx94u	187	36	the	the	DT
cord-285180-32bxx94u	187	37	results	result	NNS
cord-285180-32bxx94u	187	38	of	of	IN
cord-285180-32bxx94u	187	39	the	the	DT
cord-285180-32bxx94u	187	40	proteomic	proteomic	JJ
cord-285180-32bxx94u	187	41	analysis	analysis	NN
cord-285180-32bxx94u	187	42	(	(	-LRB-
cord-285180-32bxx94u	187	43	Fig	Fig	NNP
cord-285180-32bxx94u	187	44	.	.	.
cord-285180-32bxx94u	187	45	5	5	CD
cord-285180-32bxx94u	187	46	)	)	-RRB-
cord-285180-32bxx94u	187	47	.	.	.
cord-285180-32bxx94u	188	1	We	-PRON-	PRP
cord-285180-32bxx94u	188	2	were	be	VBD
cord-285180-32bxx94u	188	3	able	able	JJ
cord-285180-32bxx94u	188	4	to	to	TO
cord-285180-32bxx94u	188	5	detect	detect	VB
cord-285180-32bxx94u	188	6	mRNAs	mrnas	PRP
cord-285180-32bxx94u	188	7	corresponding	correspond	VBG
cord-285180-32bxx94u	188	8	to	to	IN
cord-285180-32bxx94u	188	9	nearly	nearly	RB
cord-285180-32bxx94u	188	10	all	all	DT
cord-285180-32bxx94u	188	11	proteins	protein	NNS
cord-285180-32bxx94u	188	12	identified	identify	VBN
cord-285180-32bxx94u	188	13	by	by	IN
cord-285180-32bxx94u	188	14	proteomics	proteomic	NNS
cord-285180-32bxx94u	188	15	,	,	,
cord-285180-32bxx94u	188	16	except	except	IN
cord-285180-32bxx94u	188	17	for	for	IN
cord-285180-32bxx94u	188	18	histone	histone	NN
cord-285180-32bxx94u	188	19	H4	H4	NNP
cord-285180-32bxx94u	188	20	.	.	.
cord-285180-32bxx94u	189	1	Although	although	IN
cord-285180-32bxx94u	189	2	the	the	DT
cord-285180-32bxx94u	189	3	altered	altered	JJ
cord-285180-32bxx94u	189	4	expression	expression	NN
cord-285180-32bxx94u	189	5	levels	level	NNS
cord-285180-32bxx94u	189	6	of	of	IN
cord-285180-32bxx94u	189	7	the	the	DT
cord-285180-32bxx94u	189	8	remaining	remain	VBG
cord-285180-32bxx94u	189	9	9	9	CD
cord-285180-32bxx94u	189	10	proteins	protein	NNS
cord-285180-32bxx94u	189	11	were	be	VBD
cord-285180-32bxx94u	189	12	consistent	consistent	JJ
cord-285180-32bxx94u	189	13	with	with	IN
cord-285180-32bxx94u	189	14	the	the	DT
cord-285180-32bxx94u	189	15	real	real	JJ
cord-285180-32bxx94u	189	16	-	-	HYPH
cord-285180-32bxx94u	189	17	time	time	NN
cord-285180-32bxx94u	189	18	RT	RT	NNP
cord-285180-32bxx94u	189	19	-	-	HYPH
cord-285180-32bxx94u	189	20	PCR	PCR	NNP
cord-285180-32bxx94u	189	21	results	result	NNS
cord-285180-32bxx94u	189	22	,	,	,
cord-285180-32bxx94u	189	23	we	-PRON-	PRP
cord-285180-32bxx94u	189	24	observed	observe	VBD
cord-285180-32bxx94u	189	25	only	only	RB
cord-285180-32bxx94u	189	26	modest	modest	JJ
cord-285180-32bxx94u	189	27	increase	increase	NN
cord-285180-32bxx94u	189	28	or	or	CC
cord-285180-32bxx94u	189	29	reduction	reduction	NN
cord-285180-32bxx94u	189	30	in	in	IN
cord-285180-32bxx94u	189	31	mRNA	mRNA	NNP
cord-285180-32bxx94u	189	32	levels	level	NNS
cord-285180-32bxx94u	189	33	.	.	.
cord-285180-32bxx94u	190	1	These	these	DT
cord-285180-32bxx94u	190	2	results	result	NNS
cord-285180-32bxx94u	190	3	could	could	MD
cord-285180-32bxx94u	190	4	be	be	VB
cord-285180-32bxx94u	190	5	explained	explain	VBN
cord-285180-32bxx94u	190	6	the	the	DT
cord-285180-32bxx94u	190	7	case	case	NN
cord-285180-32bxx94u	190	8	the	the	DT
cord-285180-32bxx94u	190	9	correlation	correlation	NN
cord-285180-32bxx94u	190	10	between	between	IN
cord-285180-32bxx94u	190	11	mRNA	mrna	NN
cord-285180-32bxx94u	190	12	and	and	CC
cord-285180-32bxx94u	190	13	protein	protein	NN
cord-285180-32bxx94u	190	14	abundance	abundance	NN
cord-285180-32bxx94u	190	15	could	could	MD
cord-285180-32bxx94u	190	16	be	be	VB
cord-285180-32bxx94u	190	17	insufficient	insufficient	JJ
cord-285180-32bxx94u	190	18	to	to	TO
cord-285180-32bxx94u	190	19	predict	predict	VB
cord-285180-32bxx94u	190	20	protein	protein	NN
cord-285180-32bxx94u	190	21	expression	expression	NN
cord-285180-32bxx94u	190	22	levels	level	NNS
cord-285180-32bxx94u	190	23	from	from	IN
cord-285180-32bxx94u	190	24	quantitative	quantitative	JJ
cord-285180-32bxx94u	190	25	mRNA	mRNA	NNP
cord-285180-32bxx94u	190	26	data	datum	NNS
cord-285180-32bxx94u	190	27	(	(	-LRB-
cord-285180-32bxx94u	190	28	Gygi	Gygi	NNP
cord-285180-32bxx94u	190	29	et	et	FW
cord-285180-32bxx94u	190	30	al	al	NNP
cord-285180-32bxx94u	190	31	.	.	NNP
cord-285180-32bxx94u	190	32	,	,	,
cord-285180-32bxx94u	190	33	1999	1999	CD
cord-285180-32bxx94u	190	34	)	)	-RRB-
cord-285180-32bxx94u	190	35	,	,	,
cord-285180-32bxx94u	190	36	suggesting	suggest	VBG
cord-285180-32bxx94u	190	37	that	that	IN
cord-285180-32bxx94u	190	38	the	the	DT
cord-285180-32bxx94u	190	39	differences	difference	NNS
cord-285180-32bxx94u	190	40	in	in	IN
cord-285180-32bxx94u	190	41	protein	protein	NN
cord-285180-32bxx94u	190	42	levels	level	NNS
cord-285180-32bxx94u	190	43	might	may	MD
cord-285180-32bxx94u	190	44	be	be	VB
cord-285180-32bxx94u	190	45	due	due	JJ
cord-285180-32bxx94u	190	46	to	to	IN
cord-285180-32bxx94u	190	47	post	post	JJ
cord-285180-32bxx94u	190	48	-	-	JJ
cord-285180-32bxx94u	190	49	translational	translational	JJ
cord-285180-32bxx94u	190	50	modifications	modification	NNS
cord-285180-32bxx94u	190	51	or	or	CC
cord-285180-32bxx94u	190	52	protein	protein	NN
cord-285180-32bxx94u	190	53	stability	stability	NN
cord-285180-32bxx94u	190	54	rather	rather	RB
cord-285180-32bxx94u	190	55	than	than	IN
cord-285180-32bxx94u	190	56	mRNA	mRNA	NNP
cord-285180-32bxx94u	190	57	levels	level	NNS
cord-285180-32bxx94u	190	58	.	.	.
cord-285180-32bxx94u	191	1	The	the	DT
cord-285180-32bxx94u	191	2	quantity	quantity	NN
cord-285180-32bxx94u	191	3	of	of	IN
cord-285180-32bxx94u	191	4	each	each	DT
cord-285180-32bxx94u	191	5	spot	spot	NN
cord-285180-32bxx94u	191	6	was	be	VBD
cord-285180-32bxx94u	191	7	normalized	normalize	VBN
cord-285180-32bxx94u	191	8	based	base	VBN
cord-285180-32bxx94u	191	9	on	on	IN
cord-285180-32bxx94u	191	10	the	the	DT
cord-285180-32bxx94u	191	11	total	total	JJ
cord-285180-32bxx94u	191	12	valid	valid	JJ
cord-285180-32bxx94u	191	13	spot	spot	NN
cord-285180-32bxx94u	191	14	intensity	intensity	NN
cord-285180-32bxx94u	191	15	for	for	IN
cord-285180-32bxx94u	191	16	each	each	DT
cord-285180-32bxx94u	191	17	gel	gel	NN
cord-285180-32bxx94u	191	18	and	and	CC
cord-285180-32bxx94u	191	19	the	the	DT
cord-285180-32bxx94u	191	20	relative	relative	JJ
cord-285180-32bxx94u	191	21	fold	fold	JJ
cord-285180-32bxx94u	191	22	change	change	NN
cord-285180-32bxx94u	191	23	of	of	IN
cord-285180-32bxx94u	191	24	each	each	DT
cord-285180-32bxx94u	191	25	spot	spot	NN
cord-285180-32bxx94u	191	26	was	be	VBD
cord-285180-32bxx94u	191	27	then	then	RB
cord-285180-32bxx94u	191	28	calculated	calculate	VBN
cord-285180-32bxx94u	191	29	between	between	IN
cord-285180-32bxx94u	191	30	control	control	NN
cord-285180-32bxx94u	191	31	PK	PK	NNP
cord-285180-32bxx94u	191	32	-	-	HYPH
cord-285180-32bxx94u	191	33	Neo	Neo	NNP
cord-285180-32bxx94u	191	34	and	and	CC
cord-285180-32bxx94u	191	35	PK	PK	NNP
cord-285180-32bxx94u	191	36	-	-	HYPH
cord-285180-32bxx94u	191	37	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	191	38	-	-	HYPH
cord-285180-32bxx94u	191	39	N	n	CD
cord-285180-32bxx94u	191	40	cells	cell	NNS
cord-285180-32bxx94u	191	41	.	.	.
cord-285180-32bxx94u	192	1	Data	datum	NNS
cord-285180-32bxx94u	192	2	representing	represent	VBG
cord-285180-32bxx94u	192	3	three	three	CD
cord-285180-32bxx94u	192	4	independent	independent	JJ
cord-285180-32bxx94u	192	5	2DE	2de	CD
cord-285180-32bxx94u	192	6	experiments	experiment	NNS
cord-285180-32bxx94u	192	7	for	for	IN
cord-285180-32bxx94u	192	8	each	each	DT
cord-285180-32bxx94u	192	9	sample	sample	NN
cord-285180-32bxx94u	192	10	were	be	VBD
cord-285180-32bxx94u	192	11	statistically	statistically	RB
cord-285180-32bxx94u	192	12	analyzed	analyze	VBN
cord-285180-32bxx94u	192	13	and	and	CC
cord-285180-32bxx94u	192	14	error	error	NN
cord-285180-32bxx94u	192	15	bars	bar	NNS
cord-285180-32bxx94u	192	16	represent	represent	VBP
cord-285180-32bxx94u	192	17	standard	standard	JJ
cord-285180-32bxx94u	192	18	deviations	deviation	NNS
cord-285180-32bxx94u	192	19	.	.	.
cord-285180-32bxx94u	193	1	*	*	NFP
cord-285180-32bxx94u	193	2	P	p	NN
cord-285180-32bxx94u	193	3	=	=	SYM
cord-285180-32bxx94u	193	4	0.001	0.001	CD
cord-285180-32bxx94u	193	5	-	-	HYPH
cord-285180-32bxx94u	193	6	0.05	0.05	CD
cord-285180-32bxx94u	193	7	.	.	.
cord-285180-32bxx94u	194	1	Two	two	CD
cord-285180-32bxx94u	194	2	members	member	NNS
cord-285180-32bxx94u	194	3	of	of	IN
cord-285180-32bxx94u	194	4	the	the	DT
cord-285180-32bxx94u	194	5	HSP70	HSP70	NNP
cord-285180-32bxx94u	194	6	family	family	NN
cord-285180-32bxx94u	194	7	,	,	,
cord-285180-32bxx94u	194	8	glucose	glucose	NN
cord-285180-32bxx94u	194	9	-	-	HYPH
cord-285180-32bxx94u	194	10	regulated	regulate	VBN
cord-285180-32bxx94u	194	11	protein	protein	NN
cord-285180-32bxx94u	194	12	78	78	CD
cord-285180-32bxx94u	194	13	(	(	-LRB-
cord-285180-32bxx94u	194	14	GRP78	GRP78	NNP
cord-285180-32bxx94u	194	15	)	)	-RRB-
cord-285180-32bxx94u	194	16	and	and	CC
cord-285180-32bxx94u	194	17	heat	heat	NN
cord-285180-32bxx94u	194	18	shock	shock	NN
cord-285180-32bxx94u	194	19	cognate	cognate	JJ
cord-285180-32bxx94u	194	20	70-kDa	70-kda	CD
cord-285180-32bxx94u	194	21	protein	protein	NN
cord-285180-32bxx94u	194	22	(	(	-LRB-
cord-285180-32bxx94u	194	23	HSC70	HSC70	NNP
cord-285180-32bxx94u	194	24	)	)	-RRB-
cord-285180-32bxx94u	194	25	,	,	,
cord-285180-32bxx94u	194	26	were	be	VBD
cord-285180-32bxx94u	194	27	found	find	VBN
cord-285180-32bxx94u	194	28	to	to	TO
cord-285180-32bxx94u	194	29	be	be	VB
cord-285180-32bxx94u	194	30	up	up	RB
cord-285180-32bxx94u	194	31	-	-	HYPH
cord-285180-32bxx94u	194	32	regulated	regulate	VBN
cord-285180-32bxx94u	194	33	in	in	IN
cord-285180-32bxx94u	194	34	the	the	DT
cord-285180-32bxx94u	194	35	PDCoV	pdcov	NN
cord-285180-32bxx94u	194	36	N	n	NN
cord-285180-32bxx94u	194	37	-	-	HYPH
cord-285180-32bxx94u	194	38	expressing	express	VBG
cord-285180-32bxx94u	194	39	cells	cell	NNS
cord-285180-32bxx94u	194	40	by	by	IN
cord-285180-32bxx94u	194	41	the	the	DT
cord-285180-32bxx94u	194	42	proteomic	proteomic	JJ
cord-285180-32bxx94u	194	43	analysis	analysis	NN
cord-285180-32bxx94u	194	44	.	.	.
cord-285180-32bxx94u	195	1	To	to	TO
cord-285180-32bxx94u	195	2	further	further	RB
cord-285180-32bxx94u	195	3	verify	verify	VB
cord-285180-32bxx94u	195	4	the	the	DT
cord-285180-32bxx94u	195	5	dynamic	dynamic	JJ
cord-285180-32bxx94u	195	6	alterations	alteration	NNS
cord-285180-32bxx94u	195	7	in	in	IN
cord-285180-32bxx94u	195	8	Fig	Fig	NNP
cord-285180-32bxx94u	195	9	.	.	.
cord-285180-32bxx94u	196	1	5	5	LS
cord-285180-32bxx94u	196	2	.	.	.
cord-285180-32bxx94u	197	1	Transcriptional	transcriptional	JJ
cord-285180-32bxx94u	197	2	alteration	alteration	NN
cord-285180-32bxx94u	197	3	of	of	IN
cord-285180-32bxx94u	197	4	identified	identify	VBN
cord-285180-32bxx94u	197	5	cellular	cellular	JJ
cord-285180-32bxx94u	197	6	genes	gene	NNS
cord-285180-32bxx94u	197	7	in	in	IN
cord-285180-32bxx94u	197	8	PK	PK	NNP
cord-285180-32bxx94u	197	9	-	-	HYPH
cord-285180-32bxx94u	197	10	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	197	11	-	-	HYPH
cord-285180-32bxx94u	197	12	N	n	CD
cord-285180-32bxx94u	197	13	cells	cell	NNS
cord-285180-32bxx94u	197	14	.	.	.
cord-285180-32bxx94u	198	1	The	the	DT
cord-285180-32bxx94u	198	2	mRNA	mrna	NN
cord-285180-32bxx94u	198	3	level	level	NN
cord-285180-32bxx94u	198	4	of	of	IN
cord-285180-32bxx94u	198	5	each	each	DT
cord-285180-32bxx94u	198	6	gene	gene	NN
cord-285180-32bxx94u	198	7	was	be	VBD
cord-285180-32bxx94u	198	8	assessed	assess	VBN
cord-285180-32bxx94u	198	9	by	by	IN
cord-285180-32bxx94u	198	10	quantitative	quantitative	JJ
cord-285180-32bxx94u	198	11	real	real	JJ
cord-285180-32bxx94u	198	12	-	-	HYPH
cord-285180-32bxx94u	198	13	time	time	NN
cord-285180-32bxx94u	198	14	RT	RT	NNP
cord-285180-32bxx94u	198	15	-	-	HYPH
cord-285180-32bxx94u	198	16	PCR	PCR	NNP
cord-285180-32bxx94u	198	17	and	and	CC
cord-285180-32bxx94u	198	18	normalized	normalize	VBN
cord-285180-32bxx94u	198	19	to	to	IN
cord-285180-32bxx94u	198	20	that	that	DT
cord-285180-32bxx94u	198	21	of	of	IN
cord-285180-32bxx94u	198	22	porcine	porcine	NN
cord-285180-32bxx94u	198	23	␤	␤	.
cord-285180-32bxx94u	199	1	-actin	-actin	NFP
cord-285180-32bxx94u	199	2	.	.	.
cord-285180-32bxx94u	200	1	Relative	relative	JJ
cord-285180-32bxx94u	200	2	quantities	quantity	NNS
cord-285180-32bxx94u	200	3	(	(	-LRB-
cord-285180-32bxx94u	200	4	RQ	RQ	NNP
cord-285180-32bxx94u	200	5	)	)	-RRB-
cord-285180-32bxx94u	200	6	of	of	IN
cord-285180-32bxx94u	200	7	mRNA	mRNA	NNP
cord-285180-32bxx94u	200	8	accumulation	accumulation	NN
cord-285180-32bxx94u	200	9	were	be	VBD
cord-285180-32bxx94u	200	10	evaluated	evaluate	VBN
cord-285180-32bxx94u	200	11	by	by	IN
cord-285180-32bxx94u	200	12	2	2	CD
cord-285180-32bxx94u	200	13	−	−	NNP
cord-285180-32bxx94u	200	14	Ct	Ct	NNP
cord-285180-32bxx94u	200	15	method	method	NN
cord-285180-32bxx94u	200	16	and	and	CC
cord-285180-32bxx94u	200	17	the	the	DT
cord-285180-32bxx94u	200	18	relative	relative	JJ
cord-285180-32bxx94u	200	19	fold	fold	JJ
cord-285180-32bxx94u	200	20	change	change	NN
cord-285180-32bxx94u	200	21	of	of	IN
cord-285180-32bxx94u	200	22	each	each	DT
cord-285180-32bxx94u	200	23	gene	gene	NN
cord-285180-32bxx94u	200	24	was	be	VBD
cord-285180-32bxx94u	200	25	then	then	RB
cord-285180-32bxx94u	200	26	calculated	calculate	VBN
cord-285180-32bxx94u	200	27	between	between	IN
cord-285180-32bxx94u	200	28	control	control	NN
cord-285180-32bxx94u	200	29	PK	PK	NNP
cord-285180-32bxx94u	200	30	-	-	HYPH
cord-285180-32bxx94u	200	31	Neo	Neo	NNP
cord-285180-32bxx94u	200	32	and	and	CC
cord-285180-32bxx94u	200	33	PK	PK	NNP
cord-285180-32bxx94u	200	34	-	-	HYPH
cord-285180-32bxx94u	200	35	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	200	36	-	-	HYPH
cord-285180-32bxx94u	200	37	N	n	CD
cord-285180-32bxx94u	200	38	cells	cell	NNS
cord-285180-32bxx94u	200	39	.	.	.
cord-285180-32bxx94u	201	1	Results	result	NNS
cord-285180-32bxx94u	201	2	are	be	VBP
cord-285180-32bxx94u	201	3	expressed	express	VBN
cord-285180-32bxx94u	201	4	as	as	IN
cord-285180-32bxx94u	201	5	the	the	DT
cord-285180-32bxx94u	201	6	mean	mean	JJ
cord-285180-32bxx94u	201	7	values	value	NNS
cord-285180-32bxx94u	201	8	from	from	IN
cord-285180-32bxx94u	201	9	three	three	CD
cord-285180-32bxx94u	201	10	independent	independent	JJ
cord-285180-32bxx94u	201	11	experiments	experiment	NNS
cord-285180-32bxx94u	201	12	in	in	IN
cord-285180-32bxx94u	201	13	duplicate	duplicate	NN
cord-285180-32bxx94u	201	14	and	and	CC
cord-285180-32bxx94u	201	15	error	error	NN
cord-285180-32bxx94u	201	16	bars	bar	NNS
cord-285180-32bxx94u	201	17	represent	represent	VBP
cord-285180-32bxx94u	201	18	standard	standard	JJ
cord-285180-32bxx94u	201	19	deviations	deviation	NNS
cord-285180-32bxx94u	201	20	.	.	.
cord-285180-32bxx94u	202	1	*	*	NFP
cord-285180-32bxx94u	202	2	P	p	NN
cord-285180-32bxx94u	202	3	=	=	SYM
cord-285180-32bxx94u	202	4	0.001	0.001	CD
cord-285180-32bxx94u	202	5	-	-	HYPH
cord-285180-32bxx94u	202	6	0.05	0.05	CD
cord-285180-32bxx94u	202	7	;	;	:
cord-285180-32bxx94u	202	8	†	†	NN
cord-285180-32bxx94u	202	9	P	p	NN
cord-285180-32bxx94u	202	10	<	<	XX
cord-285180-32bxx94u	202	11	0.001	0.001	CD
cord-285180-32bxx94u	202	12	.	.	.
cord-285180-32bxx94u	203	1	expression	expression	NN
cord-285180-32bxx94u	203	2	of	of	IN
cord-285180-32bxx94u	203	3	these	these	DT
cord-285180-32bxx94u	203	4	stress	stress	NN
cord-285180-32bxx94u	203	5	-	-	HYPH
cord-285180-32bxx94u	203	6	response	response	NN
cord-285180-32bxx94u	203	7	proteins	protein	NNS
cord-285180-32bxx94u	203	8	under	under	IN
cord-285180-32bxx94u	203	9	the	the	DT
cord-285180-32bxx94u	203	10	influence	influence	NN
cord-285180-32bxx94u	203	11	of	of	IN
cord-285180-32bxx94u	203	12	PDCoV	pdcov	NN
cord-285180-32bxx94u	203	13	N	n	CD
cord-285180-32bxx94u	203	14	,	,	,
cord-285180-32bxx94u	203	15	we	-PRON-	PRP
cord-285180-32bxx94u	203	16	performed	perform	VBD
cord-285180-32bxx94u	203	17	time	time	NN
cord-285180-32bxx94u	203	18	-	-	HYPH
cord-285180-32bxx94u	203	19	course	course	NN
cord-285180-32bxx94u	203	20	Western	western	JJ
cord-285180-32bxx94u	203	21	blot	blot	NN
cord-285180-32bxx94u	203	22	analysis	analysis	NN
cord-285180-32bxx94u	203	23	.	.	.
cord-285180-32bxx94u	204	1	Total	total	JJ
cord-285180-32bxx94u	204	2	cellular	cellular	JJ
cord-285180-32bxx94u	204	3	lysates	lysate	NNS
cord-285180-32bxx94u	204	4	were	be	VBD
cord-285180-32bxx94u	204	5	prepared	prepare	VBN
cord-285180-32bxx94u	204	6	from	from	IN
cord-285180-32bxx94u	204	7	PK	PK	NNP
cord-285180-32bxx94u	204	8	-	-	HYPH
cord-285180-32bxx94u	204	9	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	204	10	-	-	HYPH
cord-285180-32bxx94u	204	11	N	n	CD
cord-285180-32bxx94u	204	12	cells	cell	NNS
cord-285180-32bxx94u	204	13	at	at	IN
cord-285180-32bxx94u	204	14	different	different	JJ
cord-285180-32bxx94u	204	15	time	time	NN
cord-285180-32bxx94u	204	16	points	point	NNS
cord-285180-32bxx94u	204	17	,	,	,
cord-285180-32bxx94u	204	18	and	and	CC
cord-285180-32bxx94u	204	19	the	the	DT
cord-285180-32bxx94u	204	20	expression	expression	NN
cord-285180-32bxx94u	204	21	kinetics	kinetic	NNS
cord-285180-32bxx94u	204	22	of	of	IN
cord-285180-32bxx94u	204	23	the	the	DT
cord-285180-32bxx94u	204	24	GRP78	GRP78	NNP
cord-285180-32bxx94u	205	1	and	and	CC
cord-285180-32bxx94u	205	2	HSC70	HSC70	NNP
cord-285180-32bxx94u	205	3	was	be	VBD
cord-285180-32bxx94u	205	4	compared	compare	VBN
cord-285180-32bxx94u	205	5	between	between	IN
cord-285180-32bxx94u	205	6	control	control	NN
cord-285180-32bxx94u	205	7	and	and	CC
cord-285180-32bxx94u	205	8	N	n	CD
cord-285180-32bxx94u	205	9	protein	protein	NN
cord-285180-32bxx94u	205	10	-	-	HYPH
cord-285180-32bxx94u	205	11	containing	contain	VBG
cord-285180-32bxx94u	205	12	extracts	extract	NNS
cord-285180-32bxx94u	205	13	.	.	.
cord-285180-32bxx94u	206	1	Higher	high	JJR
cord-285180-32bxx94u	206	2	expression	expression	NN
cord-285180-32bxx94u	206	3	of	of	IN
cord-285180-32bxx94u	206	4	both	both	DT
cord-285180-32bxx94u	206	5	proteins	protein	NNS
cord-285180-32bxx94u	206	6	was	be	VBD
cord-285180-32bxx94u	206	7	first	first	RB
cord-285180-32bxx94u	206	8	evident	evident	JJ
cord-285180-32bxx94u	206	9	in	in	IN
cord-285180-32bxx94u	206	10	PK	PK	NNP
cord-285180-32bxx94u	206	11	-	-	HYPH
cord-285180-32bxx94u	206	12	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	206	13	-	-	HYPH
cord-285180-32bxx94u	206	14	N	n	CD
cord-285180-32bxx94u	206	15	cells	cell	NNS
cord-285180-32bxx94u	206	16	as	as	RB
cord-285180-32bxx94u	206	17	early	early	RB
cord-285180-32bxx94u	206	18	as	as	IN
cord-285180-32bxx94u	206	19	at	at	IN
cord-285180-32bxx94u	206	20	12	12	CD
cord-285180-32bxx94u	206	21	h	h	NN
cord-285180-32bxx94u	206	22	post	post	NN
cord-285180-32bxx94u	206	23	-	-	JJ
cord-285180-32bxx94u	206	24	seeding	seed	VBG
cord-285180-32bxx94u	206	25	in	in	IN
cord-285180-32bxx94u	206	26	comparison	comparison	NN
cord-285180-32bxx94u	206	27	with	with	IN
cord-285180-32bxx94u	206	28	control	control	NN
cord-285180-32bxx94u	206	29	PK	PK	NNP
cord-285180-32bxx94u	206	30	-	-	HYPH
cord-285180-32bxx94u	206	31	Neo	Neo	NNP
cord-285180-32bxx94u	206	32	cells	cell	NNS
cord-285180-32bxx94u	206	33	,	,	,
cord-285180-32bxx94u	206	34	and	and	CC
cord-285180-32bxx94u	206	35	the	the	DT
cord-285180-32bxx94u	206	36	production	production	NN
cord-285180-32bxx94u	206	37	of	of	IN
cord-285180-32bxx94u	206	38	both	both	DT
cord-285180-32bxx94u	206	39	proteins	protein	NNS
cord-285180-32bxx94u	206	40	was	be	VBD
cord-285180-32bxx94u	206	41	persistently	persistently	RB
cord-285180-32bxx94u	206	42	high	high	JJ
cord-285180-32bxx94u	206	43	during	during	IN
cord-285180-32bxx94u	206	44	the	the	DT
cord-285180-32bxx94u	206	45	later	later	JJ
cord-285180-32bxx94u	206	46	time	time	NN
cord-285180-32bxx94u	206	47	points	point	NNS
cord-285180-32bxx94u	206	48	,	,	,
cord-285180-32bxx94u	206	49	suggesting	suggest	VBG
cord-285180-32bxx94u	206	50	that	that	IN
cord-285180-32bxx94u	206	51	their	-PRON-	PRP$
cord-285180-32bxx94u	206	52	enhanced	enhanced	JJ
cord-285180-32bxx94u	206	53	expression	expression	NN
cord-285180-32bxx94u	206	54	is	be	VBZ
cord-285180-32bxx94u	206	55	dependent	dependent	JJ
cord-285180-32bxx94u	206	56	on	on	IN
cord-285180-32bxx94u	206	57	the	the	DT
cord-285180-32bxx94u	206	58	N	n	CD
cord-285180-32bxx94u	206	59	protein	protein	NN
cord-285180-32bxx94u	206	60	(	(	-LRB-
cord-285180-32bxx94u	206	61	Fig	Fig	NNP
cord-285180-32bxx94u	206	62	.	.	.
cord-285180-32bxx94u	206	63	6	6	CD
cord-285180-32bxx94u	206	64	)	)	-RRB-
cord-285180-32bxx94u	206	65	.	.	.
cord-285180-32bxx94u	207	1	These	these	DT
cord-285180-32bxx94u	207	2	results	result	NNS
cord-285180-32bxx94u	207	3	were	be	VBD
cord-285180-32bxx94u	207	4	consistent	consistent	JJ
cord-285180-32bxx94u	207	5	with	with	IN
cord-285180-32bxx94u	207	6	the	the	DT
cord-285180-32bxx94u	207	7	proteomic	proteomic	JJ
cord-285180-32bxx94u	207	8	analysis	analysis	NN
cord-285180-32bxx94u	207	9	of	of	IN
cord-285180-32bxx94u	207	10	2DE	2de	CD
cord-285180-32bxx94u	207	11	gels	gel	NNS
cord-285180-32bxx94u	207	12	and	and	CC
cord-285180-32bxx94u	207	13	realtime	realtime	JJ
cord-285180-32bxx94u	207	14	RT	RT	NNP
cord-285180-32bxx94u	207	15	-	-	HYPH
cord-285180-32bxx94u	207	16	PCR	PCR	NNP
cord-285180-32bxx94u	207	17	,	,	,
cord-285180-32bxx94u	207	18	demonstrating	demonstrate	VBG
cord-285180-32bxx94u	207	19	that	that	IN
cord-285180-32bxx94u	207	20	the	the	DT
cord-285180-32bxx94u	207	21	synthesis	synthesis	NN
cord-285180-32bxx94u	207	22	of	of	IN
cord-285180-32bxx94u	207	23	GRP78	GRP78	NNP
cord-285180-32bxx94u	207	24	and	and	CC
cord-285180-32bxx94u	207	25	HSC70	HSC70	NNP
cord-285180-32bxx94u	207	26	is	be	VBZ
cord-285180-32bxx94u	207	27	indeed	indeed	RB
cord-285180-32bxx94u	207	28	up	up	RB
cord-285180-32bxx94u	207	29	-	-	HYPH
cord-285180-32bxx94u	207	30	regulated	regulate	VBN
cord-285180-32bxx94u	207	31	in	in	IN
cord-285180-32bxx94u	207	32	response	response	NN
cord-285180-32bxx94u	207	33	to	to	IN
cord-285180-32bxx94u	207	34	expression	expression	NN
cord-285180-32bxx94u	207	35	of	of	IN
cord-285180-32bxx94u	207	36	the	the	DT
cord-285180-32bxx94u	207	37	N	N	NNP
cord-285180-32bxx94u	207	38	protein	protein	NN
cord-285180-32bxx94u	207	39	of	of	IN
cord-285180-32bxx94u	207	40	PDCoV.	pdcov.	NN
cord-285180-32bxx94u	207	41	Since	since	IN
cord-285180-32bxx94u	207	42	viruses	virus	NNS
cord-285180-32bxx94u	207	43	are	be	VBP
cord-285180-32bxx94u	207	44	obligate	obligate	VBN
cord-285180-32bxx94u	207	45	intracellular	intracellular	JJ
cord-285180-32bxx94u	207	46	parasites	parasite	NNS
cord-285180-32bxx94u	207	47	,	,	,
cord-285180-32bxx94u	207	48	they	-PRON-	PRP
cord-285180-32bxx94u	207	49	must	must	MD
cord-285180-32bxx94u	207	50	utilize	utilize	VB
cord-285180-32bxx94u	207	51	the	the	DT
cord-285180-32bxx94u	207	52	cellular	cellular	JJ
cord-285180-32bxx94u	207	53	machinery	machinery	NN
cord-285180-32bxx94u	207	54	and	and	CC
cord-285180-32bxx94u	207	55	biosynthetic	biosynthetic	JJ
cord-285180-32bxx94u	207	56	components	component	NNS
cord-285180-32bxx94u	207	57	of	of	IN
cord-285180-32bxx94u	207	58	the	the	DT
cord-285180-32bxx94u	207	59	host	host	NN
cord-285180-32bxx94u	207	60	cell	cell	NN
cord-285180-32bxx94u	207	61	for	for	IN
cord-285180-32bxx94u	207	62	their	-PRON-	PRP$
cord-285180-32bxx94u	207	63	own	own	JJ
cord-285180-32bxx94u	207	64	replication	replication	NN
cord-285180-32bxx94u	207	65	.	.	.
cord-285180-32bxx94u	208	1	After	after	IN
cord-285180-32bxx94u	208	2	viral	viral	JJ
cord-285180-32bxx94u	208	3	infection	infection	NN
cord-285180-32bxx94u	208	4	,	,	,
cord-285180-32bxx94u	208	5	the	the	DT
cord-285180-32bxx94u	208	6	infected	infected	JJ
cord-285180-32bxx94u	208	7	cells	cell	NNS
cord-285180-32bxx94u	208	8	launch	launch	VBP
cord-285180-32bxx94u	208	9	a	a	DT
cord-285180-32bxx94u	208	10	number	number	NN
cord-285180-32bxx94u	208	11	of	of	IN
cord-285180-32bxx94u	208	12	host	host	NN
cord-285180-32bxx94u	208	13	antiviral	antiviral	JJ
cord-285180-32bxx94u	208	14	defensive	defensive	JJ
cord-285180-32bxx94u	208	15	responses	response	NNS
cord-285180-32bxx94u	208	16	,	,	,
cord-285180-32bxx94u	208	17	which	which	WDT
cord-285180-32bxx94u	208	18	are	be	VBP
cord-285180-32bxx94u	208	19	turned	turn	VBN
cord-285180-32bxx94u	208	20	on	on	RP
cord-285180-32bxx94u	208	21	to	to	TO
cord-285180-32bxx94u	208	22	eliminate	eliminate	VB
cord-285180-32bxx94u	208	23	the	the	DT
cord-285180-32bxx94u	208	24	invading	invade	VBG
cord-285180-32bxx94u	208	25	viruses	virus	NNS
cord-285180-32bxx94u	208	26	.	.	.
cord-285180-32bxx94u	209	1	On	on	IN
cord-285180-32bxx94u	209	2	the	the	DT
cord-285180-32bxx94u	209	3	other	other	JJ
cord-285180-32bxx94u	209	4	hand	hand	NN
cord-285180-32bxx94u	209	5	,	,	,
cord-285180-32bxx94u	209	6	viruses	virus	NNS
cord-285180-32bxx94u	209	7	employ	employ	VBP
cord-285180-32bxx94u	209	8	their	-PRON-	PRP$
cord-285180-32bxx94u	209	9	own	own	JJ
cord-285180-32bxx94u	209	10	evasion	evasion	NN
cord-285180-32bxx94u	209	11	strategies	strategy	NNS
cord-285180-32bxx94u	209	12	to	to	TO
cord-285180-32bxx94u	209	13	complete	complete	VB
cord-285180-32bxx94u	209	14	their	-PRON-	PRP$
cord-285180-32bxx94u	209	15	replication	replication	NN
cord-285180-32bxx94u	209	16	and	and	CC
cord-285180-32bxx94u	209	17	to	to	TO
cord-285180-32bxx94u	209	18	successfully	successfully	RB
cord-285180-32bxx94u	209	19	spread	spread	VB
cord-285180-32bxx94u	209	20	to	to	IN
cord-285180-32bxx94u	209	21	neighboring	neighboring	NN
cord-285180-32bxx94u	209	22	cells	cell	NNS
cord-285180-32bxx94u	209	23	.	.	.
cord-285180-32bxx94u	210	1	This	this	DT
cord-285180-32bxx94u	210	2	series	series	NN
cord-285180-32bxx94u	210	3	of	of	IN
cord-285180-32bxx94u	210	4	interactions	interaction	NNS
cord-285180-32bxx94u	210	5	between	between	IN
cord-285180-32bxx94u	210	6	the	the	DT
cord-285180-32bxx94u	210	7	virus	virus	NN
cord-285180-32bxx94u	210	8	and	and	CC
cord-285180-32bxx94u	210	9	host	host	NN
cord-285180-32bxx94u	210	10	results	result	NNS
cord-285180-32bxx94u	210	11	in	in	IN
cord-285180-32bxx94u	210	12	compensatory	compensatory	JJ
cord-285180-32bxx94u	210	13	modifications	modification	NNS
cord-285180-32bxx94u	210	14	in	in	IN
cord-285180-32bxx94u	210	15	cellular	cellular	JJ
cord-285180-32bxx94u	210	16	gene	gene	NN
cord-285180-32bxx94u	210	17	production	production	NN
cord-285180-32bxx94u	210	18	.	.	.
cord-285180-32bxx94u	211	1	Accordingly	accordingly	RB
cord-285180-32bxx94u	211	2	,	,	,
cord-285180-32bxx94u	211	3	numerous	numerous	JJ
cord-285180-32bxx94u	211	4	studies	study	NNS
cord-285180-32bxx94u	211	5	have	have	VBP
cord-285180-32bxx94u	211	6	been	be	VBN
cord-285180-32bxx94u	211	7	extensively	extensively	RB
cord-285180-32bxx94u	211	8	conducted	conduct	VBN
cord-285180-32bxx94u	211	9	by	by	IN
cord-285180-32bxx94u	211	10	means	mean	NNS
cord-285180-32bxx94u	211	11	of	of	IN
cord-285180-32bxx94u	211	12	various	various	JJ
cord-285180-32bxx94u	211	13	molecular	molecular	JJ
cord-285180-32bxx94u	211	14	and	and	CC
cord-285180-32bxx94u	211	15	genomic	genomic	JJ
cord-285180-32bxx94u	211	16	methods	method	NNS
cord-285180-32bxx94u	211	17	to	to	TO
cord-285180-32bxx94u	211	18	understand	understand	VB
cord-285180-32bxx94u	211	19	how	how	WRB
cord-285180-32bxx94u	211	20	the	the	DT
cord-285180-32bxx94u	211	21	altered	altered	JJ
cord-285180-32bxx94u	211	22	host	host	NN
cord-285180-32bxx94u	211	23	gene	gene	NN
cord-285180-32bxx94u	211	24	expression	expression	NN
cord-285180-32bxx94u	211	25	affects	affect	VBZ
cord-285180-32bxx94u	211	26	viral	viral	JJ
cord-285180-32bxx94u	211	27	infection	infection	NN
cord-285180-32bxx94u	211	28	and	and	CC
cord-285180-32bxx94u	211	29	the	the	DT
cord-285180-32bxx94u	211	30	associated	associate	VBN
cord-285180-32bxx94u	211	31	pathogenic	pathogenic	JJ
cord-285180-32bxx94u	211	32	processes	process	NNS
cord-285180-32bxx94u	211	33	.	.	.
cord-285180-32bxx94u	212	1	The	the	DT
cord-285180-32bxx94u	212	2	proteomic	proteomic	JJ
cord-285180-32bxx94u	212	3	analysis	analysis	NN
cord-285180-32bxx94u	212	4	coupling	couple	VBG
cord-285180-32bxx94u	212	5	high	high	JJ
cord-285180-32bxx94u	212	6	-	-	HYPH
cord-285180-32bxx94u	212	7	resolution	resolution	NN
cord-285180-32bxx94u	212	8	2DE	2DE	NNP
cord-285180-32bxx94u	212	9	and	and	CC
cord-285180-32bxx94u	212	10	MALDI	MALDI	NNP
cord-285180-32bxx94u	212	11	-	-	HYPH
cord-285180-32bxx94u	212	12	TOF	TOF	NNP
cord-285180-32bxx94u	212	13	/	/	SYM
cord-285180-32bxx94u	212	14	MS	MS	NNP
cord-285180-32bxx94u	212	15	is	be	VBZ
cord-285180-32bxx94u	212	16	a	a	DT
cord-285180-32bxx94u	212	17	tool	tool	NN
cord-285180-32bxx94u	212	18	that	that	WDT
cord-285180-32bxx94u	212	19	can	can	MD
cord-285180-32bxx94u	212	20	generate	generate	VB
cord-285180-32bxx94u	212	21	ample	ample	JJ
cord-285180-32bxx94u	212	22	data	datum	NNS
cord-285180-32bxx94u	212	23	on	on	IN
cord-285180-32bxx94u	212	24	cellular	cellular	JJ
cord-285180-32bxx94u	212	25	protein	protein	NN
cord-285180-32bxx94u	212	26	profiles	profile	NNS
cord-285180-32bxx94u	212	27	modified	modify	VBN
cord-285180-32bxx94u	212	28	by	by	IN
cord-285180-32bxx94u	212	29	viral	viral	JJ
cord-285180-32bxx94u	212	30	replication	replication	NN
cord-285180-32bxx94u	212	31	.	.	.
cord-285180-32bxx94u	213	1	With	with	IN
cord-285180-32bxx94u	213	2	the	the	DT
cord-285180-32bxx94u	213	3	proteomic	proteomic	JJ
cord-285180-32bxx94u	213	4	techniques	technique	NNS
cord-285180-32bxx94u	213	5	,	,	,
cord-285180-32bxx94u	213	6	it	-PRON-	PRP
cord-285180-32bxx94u	213	7	is	be	VBZ
cord-285180-32bxx94u	213	8	now	now	RB
cord-285180-32bxx94u	213	9	possible	possible	JJ
cord-285180-32bxx94u	213	10	to	to	TO
cord-285180-32bxx94u	213	11	identify	identify	VB
cord-285180-32bxx94u	213	12	relative	relative	JJ
cord-285180-32bxx94u	213	13	changes	change	NNS
cord-285180-32bxx94u	213	14	in	in	IN
cord-285180-32bxx94u	213	15	protein	protein	NN
cord-285180-32bxx94u	213	16	abundance	abundance	NN
cord-285180-32bxx94u	213	17	for	for	IN
cord-285180-32bxx94u	213	18	evaluation	evaluation	NN
cord-285180-32bxx94u	213	19	of	of	IN
cord-285180-32bxx94u	213	20	host	host	NN
cord-285180-32bxx94u	213	21	cellular	cellular	JJ
cord-285180-32bxx94u	213	22	Fig	Fig	NNP
cord-285180-32bxx94u	213	23	.	.	.
cord-285180-32bxx94u	214	1	6	6	LS
cord-285180-32bxx94u	214	2	.	.	.
cord-285180-32bxx94u	215	1	Differential	differential	JJ
cord-285180-32bxx94u	215	2	expression	expression	NN
cord-285180-32bxx94u	215	3	of	of	IN
cord-285180-32bxx94u	215	4	the	the	DT
cord-285180-32bxx94u	215	5	HSP70	HSP70	NNP
cord-285180-32bxx94u	215	6	family	family	NN
cord-285180-32bxx94u	215	7	in	in	IN
cord-285180-32bxx94u	215	8	PK	PK	NNP
cord-285180-32bxx94u	215	9	-	-	HYPH
cord-285180-32bxx94u	215	10	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	215	11	-	-	HYPH
cord-285180-32bxx94u	215	12	N	n	CD
cord-285180-32bxx94u	215	13	cells	cell	NNS
cord-285180-32bxx94u	215	14	.	.	.
cord-285180-32bxx94u	216	1	Cell	cell	NN
cord-285180-32bxx94u	216	2	lysates	lysate	NNS
cord-285180-32bxx94u	216	3	were	be	VBD
cord-285180-32bxx94u	216	4	prepared	prepare	VBN
cord-285180-32bxx94u	216	5	from	from	IN
cord-285180-32bxx94u	216	6	PDCoV	pdcov	NN
cord-285180-32bxx94u	216	7	N	n	CD
cord-285180-32bxx94u	216	8	gene	gene	NN
cord-285180-32bxx94u	216	9	-	-	HYPH
cord-285180-32bxx94u	216	10	expressing	express	VBG
cord-285180-32bxx94u	216	11	PK	PK	NNP
cord-285180-32bxx94u	216	12	cells	cell	NNS
cord-285180-32bxx94u	216	13	at	at	IN
cord-285180-32bxx94u	216	14	indicated	indicate	VBN
cord-285180-32bxx94u	216	15	time	time	NN
cord-285180-32bxx94u	216	16	points	point	NNS
cord-285180-32bxx94u	216	17	and	and	CC
cord-285180-32bxx94u	216	18	immunoblotted	immunoblotte	VBN
cord-285180-32bxx94u	216	19	to	to	TO
cord-285180-32bxx94u	216	20	determine	determine	VB
cord-285180-32bxx94u	216	21	the	the	DT
cord-285180-32bxx94u	216	22	expression	expression	NN
cord-285180-32bxx94u	216	23	profile	profile	NN
cord-285180-32bxx94u	216	24	of	of	IN
cord-285180-32bxx94u	216	25	each	each	DT
cord-285180-32bxx94u	216	26	protein	protein	NN
cord-285180-32bxx94u	216	27	with	with	IN
cord-285180-32bxx94u	216	28	antibodies	antibody	NNS
cord-285180-32bxx94u	216	29	specific	specific	JJ
cord-285180-32bxx94u	216	30	for	for	IN
cord-285180-32bxx94u	216	31	GRP78	GRP78	NNP
cord-285180-32bxx94u	216	32	and	and	CC
cord-285180-32bxx94u	216	33	HSC70	HSC70	NNP
cord-285180-32bxx94u	216	34	(	(	-LRB-
cord-285180-32bxx94u	216	35	top	top	JJ
cord-285180-32bxx94u	216	36	to	to	IN
cord-285180-32bxx94u	216	37	second	second	JJ
cord-285180-32bxx94u	216	38	panels	panel	NNS
cord-285180-32bxx94u	216	39	)	)	-RRB-
cord-285180-32bxx94u	216	40	.	.	.
cord-285180-32bxx94u	217	1	The	the	DT
cord-285180-32bxx94u	217	2	blot	blot	NN
cord-285180-32bxx94u	217	3	was	be	VBD
cord-285180-32bxx94u	217	4	also	also	RB
cord-285180-32bxx94u	217	5	reacted	react	VBN
cord-285180-32bxx94u	217	6	with	with	IN
cord-285180-32bxx94u	217	7	anti	anti	JJ
cord-285180-32bxx94u	217	8	-	-	JJ
cord-285180-32bxx94u	217	9	His	-PRON-	PRP$
cord-285180-32bxx94u	217	10	tag	tag	NN
cord-285180-32bxx94u	217	11	(	(	-LRB-
cord-285180-32bxx94u	217	12	third	third	JJ
cord-285180-32bxx94u	217	13	panel	panel	NN
cord-285180-32bxx94u	217	14	)	)	-RRB-
cord-285180-32bxx94u	217	15	and	and	CC
cord-285180-32bxx94u	217	16	anti-	anti-	JJ
cord-285180-32bxx94u	217	17	␤	␤	``
cord-285180-32bxx94u	217	18	-actin	-actin	WP
cord-285180-32bxx94u	217	19	(	(	-LRB-
cord-285180-32bxx94u	217	20	bottom	bottom	JJ
cord-285180-32bxx94u	217	21	panel	panel	NN
cord-285180-32bxx94u	217	22	)	)	-RRB-
cord-285180-32bxx94u	217	23	antibodies	antibody	NNS
cord-285180-32bxx94u	217	24	to	to	TO
cord-285180-32bxx94u	217	25	confirm	confirm	VB
cord-285180-32bxx94u	217	26	the	the	DT
cord-285180-32bxx94u	217	27	status	status	NN
cord-285180-32bxx94u	217	28	of	of	IN
cord-285180-32bxx94u	217	29	N	n	CD
cord-285180-32bxx94u	217	30	expression	expression	NN
cord-285180-32bxx94u	217	31	and	and	CC
cord-285180-32bxx94u	217	32	equal	equal	JJ
cord-285180-32bxx94u	217	33	protein	protein	NN
cord-285180-32bxx94u	217	34	loading	loading	NN
cord-285180-32bxx94u	217	35	,	,	,
cord-285180-32bxx94u	217	36	respectively	respectively	RB
cord-285180-32bxx94u	217	37	.	.	.
cord-285180-32bxx94u	218	1	Each	each	DT
cord-285180-32bxx94u	218	2	cellular	cellular	JJ
cord-285180-32bxx94u	218	3	protein	protein	NN
cord-285180-32bxx94u	218	4	expression	expression	NN
cord-285180-32bxx94u	218	5	was	be	VBD
cord-285180-32bxx94u	218	6	quantitatively	quantitatively	RB
cord-285180-32bxx94u	218	7	analyzed	analyze	VBN
cord-285180-32bxx94u	218	8	by	by	IN
cord-285180-32bxx94u	218	9	densitometry	densitometry	NN
cord-285180-32bxx94u	218	10	in	in	IN
cord-285180-32bxx94u	218	11	terms	term	NNS
cord-285180-32bxx94u	218	12	of	of	IN
cord-285180-32bxx94u	218	13	the	the	DT
cord-285180-32bxx94u	218	14	relative	relative	JJ
cord-285180-32bxx94u	218	15	density	density	NN
cord-285180-32bxx94u	218	16	value	value	NN
cord-285180-32bxx94u	218	17	to	to	IN
cord-285180-32bxx94u	218	18	the	the	DT
cord-285180-32bxx94u	218	19	␤	␤	NNP
cord-285180-32bxx94u	218	20	-actin	-actin	NNP
cord-285180-32bxx94u	218	21	gene	gene	NN
cord-285180-32bxx94u	218	22	and	and	CC
cord-285180-32bxx94u	218	23	PK	PK	NNP
cord-285180-32bxx94u	218	24	-	-	HYPH
cord-285180-32bxx94u	218	25	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	218	26	-	-	HYPH
cord-285180-32bxx94u	218	27	N	n	CD
cord-285180-32bxx94u	218	28	sample	sample	NN
cord-285180-32bxx94u	218	29	results	result	NNS
cord-285180-32bxx94u	218	30	were	be	VBD
cord-285180-32bxx94u	218	31	compared	compare	VBN
cord-285180-32bxx94u	218	32	to	to	IN
cord-285180-32bxx94u	218	33	PK	PK	NNP
cord-285180-32bxx94u	218	34	-	-	HYPH
cord-285180-32bxx94u	218	35	control	control	NN
cord-285180-32bxx94u	218	36	results	result	NNS
cord-285180-32bxx94u	218	37	.	.	.
cord-285180-32bxx94u	219	1	Values	value	NNS
cord-285180-32bxx94u	219	2	are	be	VBP
cord-285180-32bxx94u	219	3	representative	representative	JJ
cord-285180-32bxx94u	219	4	of	of	IN
cord-285180-32bxx94u	219	5	the	the	DT
cord-285180-32bxx94u	219	6	mean	mean	NN
cord-285180-32bxx94u	219	7	from	from	IN
cord-285180-32bxx94u	219	8	three	three	CD
cord-285180-32bxx94u	219	9	independent	independent	JJ
cord-285180-32bxx94u	219	10	experiments	experiment	NNS
cord-285180-32bxx94u	219	11	and	and	CC
cord-285180-32bxx94u	219	12	error	error	NN
cord-285180-32bxx94u	219	13	bars	bar	NNS
cord-285180-32bxx94u	220	1	denote	denote	VB
cord-285180-32bxx94u	220	2	standard	standard	JJ
cord-285180-32bxx94u	220	3	deviations	deviation	NNS
cord-285180-32bxx94u	220	4	.	.	.
cord-285180-32bxx94u	221	1	*	*	NFP
cord-285180-32bxx94u	221	2	P	p	NN
cord-285180-32bxx94u	221	3	=	=	SYM
cord-285180-32bxx94u	221	4	0.001	0.001	CD
cord-285180-32bxx94u	221	5	-	-	HYPH
cord-285180-32bxx94u	221	6	0.05	0.05	CD
cord-285180-32bxx94u	221	7	;	;	:
cord-285180-32bxx94u	221	8	†	†	NN
cord-285180-32bxx94u	221	9	P	p	NN
cord-285180-32bxx94u	221	10	<	<	XX
cord-285180-32bxx94u	221	11	0.001	0.001	CD
cord-285180-32bxx94u	221	12	.	.	.
cord-285180-32bxx94u	222	1	responses	response	NNS
cord-285180-32bxx94u	222	2	to	to	IN
cord-285180-32bxx94u	222	3	viral	viral	JJ
cord-285180-32bxx94u	222	4	infection	infection	NN
cord-285180-32bxx94u	222	5	or	or	CC
cord-285180-32bxx94u	222	6	viral	viral	JJ
cord-285180-32bxx94u	222	7	protein	protein	NN
cord-285180-32bxx94u	222	8	expression	expression	NN
cord-285180-32bxx94u	222	9	and	and	CC
cord-285180-32bxx94u	222	10	to	to	TO
cord-285180-32bxx94u	222	11	gain	gain	VB
cord-285180-32bxx94u	222	12	specific	specific	JJ
cord-285180-32bxx94u	222	13	insights	insight	NNS
cord-285180-32bxx94u	222	14	into	into	IN
cord-285180-32bxx94u	222	15	the	the	DT
cord-285180-32bxx94u	222	16	cellular	cellular	JJ
cord-285180-32bxx94u	222	17	mechanisms	mechanism	NNS
cord-285180-32bxx94u	222	18	involved	involve	VBN
cord-285180-32bxx94u	222	19	in	in	IN
cord-285180-32bxx94u	222	20	viral	viral	JJ
cord-285180-32bxx94u	222	21	pathogenesis	pathogenesis	NN
cord-285180-32bxx94u	222	22	(	(	-LRB-
cord-285180-32bxx94u	222	23	Alfonso	Alfonso	NNP
cord-285180-32bxx94u	222	24	et	et	NNP
cord-285180-32bxx94u	222	25	al	al	NNP
cord-285180-32bxx94u	222	26	.	.	.
cord-285180-32bxx94u	223	1	,	,	,
cord-285180-32bxx94u	223	2	2004	2004	CD
cord-285180-32bxx94u	223	3	;	;	:
cord-285180-32bxx94u	223	4	Brasier	Brasier	NNP
cord-285180-32bxx94u	223	5	et	et	NNP
cord-285180-32bxx94u	223	6	al	al	NNP
cord-285180-32bxx94u	223	7	.	.	NNP
cord-285180-32bxx94u	223	8	,	,	,
cord-285180-32bxx94u	223	9	2004	2004	CD
cord-285180-32bxx94u	223	10	;	;	:
cord-285180-32bxx94u	223	11	Neuman	Neuman	NNP
cord-285180-32bxx94u	223	12	et	et	NNP
cord-285180-32bxx94u	223	13	al	al	NNP
cord-285180-32bxx94u	223	14	.	.	NNP
cord-285180-32bxx94u	223	15	,	,	,
cord-285180-32bxx94u	223	16	2008	2008	CD
cord-285180-32bxx94u	223	17	;	;	.
cord-285180-32bxx94u	224	1	Oh	oh	UH
cord-285180-32bxx94u	224	2	and	and	CC
cord-285180-32bxx94u	224	3	Lee	Lee	NNP
cord-285180-32bxx94u	224	4	,	,	,
cord-285180-32bxx94u	224	5	2012	2012	CD
cord-285180-32bxx94u	224	6	;	;	:
cord-285180-32bxx94u	224	7	Ringrose	Ringrose	NNP
cord-285180-32bxx94u	224	8	et	et	NNP
cord-285180-32bxx94u	224	9	al	al	NNP
cord-285180-32bxx94u	224	10	.	.	NNP
cord-285180-32bxx94u	224	11	,	,	,
cord-285180-32bxx94u	224	12	2008	2008	CD
cord-285180-32bxx94u	224	13	;	;	.
cord-285180-32bxx94u	225	1	Sagong	Sagong	NNP
cord-285180-32bxx94u	225	2	and	and	CC
cord-285180-32bxx94u	225	3	Lee	Lee	NNP
cord-285180-32bxx94u	225	4	,	,	,
cord-285180-32bxx94u	225	5	2010	2010	CD
cord-285180-32bxx94u	225	6	;	;	:
cord-285180-32bxx94u	225	7	Zhang	Zhang	NNP
cord-285180-32bxx94u	225	8	et	et	NNP
cord-285180-32bxx94u	225	9	al	al	NNP
cord-285180-32bxx94u	225	10	.	.	NNP
cord-285180-32bxx94u	225	11	,	,	,
cord-285180-32bxx94u	225	12	2008	2008	CD
cord-285180-32bxx94u	225	13	)	)	-RRB-
cord-285180-32bxx94u	225	14	.	.	.
cord-285180-32bxx94u	226	1	In	in	IN
cord-285180-32bxx94u	226	2	the	the	DT
cord-285180-32bxx94u	226	3	present	present	JJ
cord-285180-32bxx94u	226	4	work	work	NN
cord-285180-32bxx94u	226	5	,	,	,
cord-285180-32bxx94u	226	6	a	a	DT
cord-285180-32bxx94u	226	7	proteomic	proteomic	JJ
cord-285180-32bxx94u	226	8	approach	approach	NN
cord-285180-32bxx94u	226	9	was	be	VBD
cord-285180-32bxx94u	226	10	applied	apply	VBN
cord-285180-32bxx94u	226	11	for	for	IN
cord-285180-32bxx94u	226	12	profiling	profile	VBG
cord-285180-32bxx94u	226	13	the	the	DT
cord-285180-32bxx94u	226	14	global	global	JJ
cord-285180-32bxx94u	226	15	protein	protein	NN
cord-285180-32bxx94u	226	16	expression	expression	NN
cord-285180-32bxx94u	226	17	changes	change	NNS
cord-285180-32bxx94u	226	18	in	in	IN
cord-285180-32bxx94u	226	19	host	host	NN
cord-285180-32bxx94u	226	20	cells	cell	NNS
cord-285180-32bxx94u	226	21	in	in	IN
cord-285180-32bxx94u	226	22	response	response	NN
cord-285180-32bxx94u	226	23	to	to	IN
cord-285180-32bxx94u	226	24	the	the	DT
cord-285180-32bxx94u	226	25	N	N	NNP
cord-285180-32bxx94u	226	26	protein	protein	NN
cord-285180-32bxx94u	226	27	of	of	IN
cord-285180-32bxx94u	226	28	PDCoV	pdcov	NN
cord-285180-32bxx94u	226	29	,	,	,
cord-285180-32bxx94u	226	30	which	which	WDT
cord-285180-32bxx94u	226	31	is	be	VBZ
cord-285180-32bxx94u	226	32	a	a	DT
cord-285180-32bxx94u	226	33	major	major	JJ
cord-285180-32bxx94u	226	34	constituent	constituent	NN
cord-285180-32bxx94u	226	35	of	of	IN
cord-285180-32bxx94u	226	36	the	the	DT
cord-285180-32bxx94u	226	37	virion	virion	NN
cord-285180-32bxx94u	226	38	and	and	CC
cord-285180-32bxx94u	226	39	infected	infected	JJ
cord-285180-32bxx94u	226	40	cells	cell	NNS
cord-285180-32bxx94u	226	41	.	.	.
cord-285180-32bxx94u	227	1	Therefore	therefore	RB
cord-285180-32bxx94u	227	2	,	,	,
cord-285180-32bxx94u	227	3	we	-PRON-	PRP
cord-285180-32bxx94u	227	4	initially	initially	RB
cord-285180-32bxx94u	227	5	established	establish	VBD
cord-285180-32bxx94u	227	6	a	a	DT
cord-285180-32bxx94u	227	7	porcine	porcine	JJ
cord-285180-32bxx94u	227	8	cell	cell	NN
cord-285180-32bxx94u	227	9	line	line	NN
cord-285180-32bxx94u	227	10	stably	stably	RB
cord-285180-32bxx94u	227	11	expressing	express	VBG
cord-285180-32bxx94u	227	12	the	the	DT
cord-285180-32bxx94u	227	13	PDCoV	pdcov	NN
cord-285180-32bxx94u	227	14	N	n	CD
cord-285180-32bxx94u	227	15	protein	protein	NN
cord-285180-32bxx94u	227	16	and	and	CC
cord-285180-32bxx94u	227	17	then	then	RB
cord-285180-32bxx94u	227	18	characterized	characterize	VBD
cord-285180-32bxx94u	227	19	the	the	DT
cord-285180-32bxx94u	227	20	N	N	NNP
cord-285180-32bxx94u	227	21	protein	protein	NN
cord-285180-32bxx94u	227	22	produced	produce	VBN
cord-285180-32bxx94u	227	23	in	in	IN
cord-285180-32bxx94u	227	24	those	those	DT
cord-285180-32bxx94u	227	25	cells	cell	NNS
cord-285180-32bxx94u	227	26	.	.	.
cord-285180-32bxx94u	228	1	Due	due	IN
cord-285180-32bxx94u	228	2	to	to	IN
cord-285180-32bxx94u	228	3	the	the	DT
cord-285180-32bxx94u	228	4	absence	absence	NN
cord-285180-32bxx94u	228	5	of	of	IN
cord-285180-32bxx94u	228	6	cysteine	cysteine	NN
cord-285180-32bxx94u	228	7	residues	residue	NNS
cord-285180-32bxx94u	228	8	,	,	,
cord-285180-32bxx94u	228	9	a	a	DT
cord-285180-32bxx94u	228	10	disulfide	disulfide	RB
cord-285180-32bxx94u	228	11	-	-	HYPH
cord-285180-32bxx94u	228	12	linked	link	VBN
cord-285180-32bxx94u	228	13	homodimeric	homodimeric	NNP
cord-285180-32bxx94u	228	14	N	n	CD
cord-285180-32bxx94u	228	15	protein	protein	NN
cord-285180-32bxx94u	228	16	of	of	IN
cord-285180-32bxx94u	228	17	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	228	18	was	be	VBD
cord-285180-32bxx94u	228	19	not	not	RB
cord-285180-32bxx94u	228	20	detected	detect	VBN
cord-285180-32bxx94u	228	21	in	in	IN
cord-285180-32bxx94u	228	22	PK	PK	NNP
cord-285180-32bxx94u	228	23	-	-	HYPH
cord-285180-32bxx94u	228	24	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	228	25	-	-	HYPH
cord-285180-32bxx94u	228	26	N	n	CD
cord-285180-32bxx94u	228	27	cells	cell	NNS
cord-285180-32bxx94u	228	28	.	.	.
cord-285180-32bxx94u	229	1	Rather	rather	RB
cord-285180-32bxx94u	229	2	,	,	,
cord-285180-32bxx94u	229	3	the	the	DT
cord-285180-32bxx94u	229	4	PDCoV	pdcov	NN
cord-285180-32bxx94u	229	5	N	N	NNP
cord-285180-32bxx94u	229	6	protein	protein	NN
cord-285180-32bxx94u	229	7	was	be	VBD
cord-285180-32bxx94u	229	8	shown	show	VBN
cord-285180-32bxx94u	229	9	to	to	TO
cord-285180-32bxx94u	229	10	be	be	VB
cord-285180-32bxx94u	229	11	self	self	NN
cord-285180-32bxx94u	229	12	-	-	HYPH
cord-285180-32bxx94u	229	13	assembled	assemble	VBN
cord-285180-32bxx94u	229	14	via	via	IN
cord-285180-32bxx94u	229	15	non	non	JJ
cord-285180-32bxx94u	229	16	-	-	JJ
cord-285180-32bxx94u	229	17	covalent	covalent	JJ
cord-285180-32bxx94u	229	18	oligomerization	oligomerization	NN
cord-285180-32bxx94u	229	19	as	as	IN
cord-285180-32bxx94u	229	20	a	a	DT
cord-285180-32bxx94u	229	21	structural	structural	JJ
cord-285180-32bxx94u	229	22	component	component	NN
cord-285180-32bxx94u	229	23	for	for	IN
cord-285180-32bxx94u	229	24	formation	formation	NN
cord-285180-32bxx94u	229	25	of	of	IN
cord-285180-32bxx94u	229	26	the	the	DT
cord-285180-32bxx94u	229	27	viral	viral	JJ
cord-285180-32bxx94u	229	28	capsid	capsid	NN
cord-285180-32bxx94u	229	29	.	.	.
cord-285180-32bxx94u	230	1	Interestingly	interestingly	RB
cord-285180-32bxx94u	230	2	,	,	,
cord-285180-32bxx94u	230	3	the	the	DT
cord-285180-32bxx94u	230	4	N	n	CD
cord-285180-32bxx94u	230	5	protein	protein	NN
cord-285180-32bxx94u	230	6	of	of	IN
cord-285180-32bxx94u	230	7	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	230	8	was	be	VBD
cord-285180-32bxx94u	230	9	found	find	VBN
cord-285180-32bxx94u	230	10	to	to	TO
cord-285180-32bxx94u	230	11	be	be	VB
cord-285180-32bxx94u	230	12	predominantly	predominantly	RB
cord-285180-32bxx94u	230	13	present	present	JJ
cord-285180-32bxx94u	230	14	in	in	IN
cord-285180-32bxx94u	230	15	both	both	CC
cord-285180-32bxx94u	230	16	the	the	DT
cord-285180-32bxx94u	230	17	cytoplasm	cytoplasm	NN
cord-285180-32bxx94u	230	18	and	and	CC
cord-285180-32bxx94u	230	19	nucleolus	nucleolus	NN
cord-285180-32bxx94u	230	20	of	of	IN
cord-285180-32bxx94u	230	21	PK	PK	NNP
cord-285180-32bxx94u	230	22	-	-	HYPH
cord-285180-32bxx94u	230	23	PDCoV	PDCoV	NNP
cord-285180-32bxx94u	230	24	-	-	HYPH
cord-285180-32bxx94u	230	25	N	n	CD
cord-285180-32bxx94u	230	26	cells	cell	NNS
cord-285180-32bxx94u	230	27	.	.	.
cord-285180-32bxx94u	231	1	The	the	DT
cord-285180-32bxx94u	231	2	localization	localization	NN
cord-285180-32bxx94u	231	3	of	of	IN
cord-285180-32bxx94u	231	4	nidovirus	nidovirus	NNP
cord-285180-32bxx94u	231	5	N	n	CD
cord-285180-32bxx94u	231	6	proteins	protein	NNS
cord-285180-32bxx94u	231	7	to	to	IN
cord-285180-32bxx94u	231	8	the	the	DT
cord-285180-32bxx94u	231	9	nucleolus	nucleolus	NN
cord-285180-32bxx94u	231	10	may	may	MD
cord-285180-32bxx94u	231	11	be	be	VB
cord-285180-32bxx94u	231	12	necessary	necessary	JJ
cord-285180-32bxx94u	231	13	for	for	IN
cord-285180-32bxx94u	231	14	control	control	NN
cord-285180-32bxx94u	231	15	of	of	IN
cord-285180-32bxx94u	231	16	RNA	RNA	NNP
cord-285180-32bxx94u	231	17	synthesis	synthesis	NN
cord-285180-32bxx94u	231	18	or	or	CC
cord-285180-32bxx94u	231	19	ribosome	ribosome	NN
cord-285180-32bxx94u	231	20	biogenesis	biogenesis	NN
cord-285180-32bxx94u	231	21	via	via	IN
cord-285180-32bxx94u	231	22	association	association	NN
cord-285180-32bxx94u	231	23	with	with	IN
cord-285180-32bxx94u	231	24	ribosomal	ribosomal	JJ
cord-285180-32bxx94u	231	25	subunits	subunit	NNS
cord-285180-32bxx94u	231	26	and	and	CC
cord-285180-32bxx94u	231	27	interaction	interaction	NN
cord-285180-32bxx94u	231	28	with	with	IN
cord-285180-32bxx94u	231	29	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	231	30	proteins	protein	NNS
cord-285180-32bxx94u	232	1	(	(	-LRB-
cord-285180-32bxx94u	232	2	Chen	Chen	NNP
cord-285180-32bxx94u	232	3	et	et	NNP
cord-285180-32bxx94u	232	4	al	al	NNP
cord-285180-32bxx94u	232	5	.	.	.
cord-285180-32bxx94u	233	1	,	,	,
cord-285180-32bxx94u	233	2	2002	2002	CD
cord-285180-32bxx94u	233	3	;	;	:
cord-285180-32bxx94u	233	4	Wurm	Wurm	NNP
cord-285180-32bxx94u	233	5	et	et	NNP
cord-285180-32bxx94u	233	6	al	al	NNP
cord-285180-32bxx94u	233	7	.	.	NNP
cord-285180-32bxx94u	233	8	,	,	,
cord-285180-32bxx94u	233	9	2001	2001	CD
cord-285180-32bxx94u	233	10	;	;	:
cord-285180-32bxx94u	233	11	Yoo	Yoo	NNP
cord-285180-32bxx94u	233	12	et	et	NNP
cord-285180-32bxx94u	233	13	al	al	NNP
cord-285180-32bxx94u	233	14	.	.	NNP
cord-285180-32bxx94u	233	15	,	,	,
cord-285180-32bxx94u	233	16	2003	2003	CD
cord-285180-32bxx94u	233	17	;	;	:
cord-285180-32bxx94u	233	18	)	)	-RRB-
cord-285180-32bxx94u	233	19	.	.	.
cord-285180-32bxx94u	234	1	Similarly	similarly	RB
cord-285180-32bxx94u	234	2	,	,	,
cord-285180-32bxx94u	234	3	the	the	DT
cord-285180-32bxx94u	234	4	PDCoV	pdcov	NN
cord-285180-32bxx94u	234	5	N	n	NN
cord-285180-32bxx94u	234	6	protein	protein	NN
cord-285180-32bxx94u	234	7	may	may	MD
cord-285180-32bxx94u	234	8	participate	participate	VB
cord-285180-32bxx94u	234	9	in	in	IN
cord-285180-32bxx94u	234	10	such	such	PDT
cord-285180-32bxx94u	234	11	a	a	DT
cord-285180-32bxx94u	234	12	viral	viral	JJ
cord-285180-32bxx94u	234	13	strategy	strategy	NN
cord-285180-32bxx94u	234	14	to	to	TO
cord-285180-32bxx94u	234	15	favor	favor	VB
cord-285180-32bxx94u	234	16	viral	viral	JJ
cord-285180-32bxx94u	234	17	replication	replication	NN
cord-285180-32bxx94u	234	18	and	and	CC
cord-285180-32bxx94u	234	19	pathogenesis	pathogenesis	NN
cord-285180-32bxx94u	234	20	.	.	.
cord-285180-32bxx94u	235	1	In	in	IN
cord-285180-32bxx94u	235	2	addition	addition	NN
cord-285180-32bxx94u	235	3	,	,	,
cord-285180-32bxx94u	235	4	the	the	DT
cord-285180-32bxx94u	235	5	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	235	6	localization	localization	NN
cord-285180-32bxx94u	235	7	sequence	sequence	NN
cord-285180-32bxx94u	235	8	detector	detector	NN
cord-285180-32bxx94u	235	9	program	program	NN
cord-285180-32bxx94u	235	10	(	(	-LRB-
cord-285180-32bxx94u	235	11	http://www.compbio.dundee.ac	http://www.compbio.dundee.ac	NNP
cord-285180-32bxx94u	235	12	.	.	.
cord-285180-32bxx94u	236	1	uk	uk	NNP
cord-285180-32bxx94u	236	2	/	/	SYM
cord-285180-32bxx94u	236	3	www	www	NNP
cord-285180-32bxx94u	236	4	-	-	HYPH
cord-285180-32bxx94u	236	5	nod/	nod/	JJ
cord-285180-32bxx94u	236	6	)	)	-RRB-
cord-285180-32bxx94u	236	7	predicted	predict	VBD
cord-285180-32bxx94u	236	8	that	that	IN
cord-285180-32bxx94u	236	9	PDCoV	pdcov	NN
cord-285180-32bxx94u	236	10	N	n	CD
cord-285180-32bxx94u	236	11	harbors	harbor	VBZ
cord-285180-32bxx94u	236	12	a	a	DT
cord-285180-32bxx94u	236	13	putative	putative	JJ
cord-285180-32bxx94u	236	14	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	236	15	localization	localization	NN
cord-285180-32bxx94u	236	16	signal	signal	NN
cord-285180-32bxx94u	236	17	(	(	-LRB-
cord-285180-32bxx94u	236	18	NoLS	NoLS	NNP
cord-285180-32bxx94u	236	19	)	)	-RRB-
cord-285180-32bxx94u	236	20	consisting	consist	VBG
cord-285180-32bxx94u	236	21	of	of	IN
cord-285180-32bxx94u	236	22	a	a	DT
cord-285180-32bxx94u	236	23	stretch	stretch	NN
cord-285180-32bxx94u	236	24	of	of	IN
cord-285180-32bxx94u	236	25	basic	basic	JJ
cord-285180-32bxx94u	236	26	amino	amino	NN
cord-285180-32bxx94u	236	27	acids	acid	NNS
cord-285180-32bxx94u	236	28	.	.	.
cord-285180-32bxx94u	237	1	Therefore	therefore	RB
cord-285180-32bxx94u	237	2	,	,	,
cord-285180-32bxx94u	237	3	further	further	JJ
cord-285180-32bxx94u	237	4	research	research	NN
cord-285180-32bxx94u	237	5	is	be	VBZ
cord-285180-32bxx94u	237	6	needed	need	VBN
cord-285180-32bxx94u	237	7	to	to	TO
cord-285180-32bxx94u	237	8	identify	identify	VB
cord-285180-32bxx94u	237	9	a	a	DT
cord-285180-32bxx94u	237	10	functional	functional	JJ
cord-285180-32bxx94u	237	11	NoLS	nol	NNS
cord-285180-32bxx94u	237	12	to	to	TO
cord-285180-32bxx94u	237	13	confirm	confirm	VB
cord-285180-32bxx94u	237	14	the	the	DT
cord-285180-32bxx94u	237	15	intracellular	intracellular	JJ
cord-285180-32bxx94u	237	16	localization	localization	NN
cord-285180-32bxx94u	237	17	of	of	IN
cord-285180-32bxx94u	237	18	the	the	DT
cord-285180-32bxx94u	237	19	PDCoV	pdcov	NN
cord-285180-32bxx94u	237	20	N	n	CD
cord-285180-32bxx94u	237	21	protein	protein	NN
cord-285180-32bxx94u	237	22	.	.	.
cord-285180-32bxx94u	238	1	These	these	DT
cord-285180-32bxx94u	238	2	biological	biological	JJ
cord-285180-32bxx94u	238	3	characteristics	characteristic	NNS
cord-285180-32bxx94u	238	4	of	of	IN
cord-285180-32bxx94u	238	5	N	n	CD
cord-285180-32bxx94u	238	6	gene	gene	NN
cord-285180-32bxx94u	238	7	-	-	HYPH
cord-285180-32bxx94u	238	8	expressing	express	VBG
cord-285180-32bxx94u	238	9	cells	cell	NNS
cord-285180-32bxx94u	238	10	have	have	VBP
cord-285180-32bxx94u	238	11	yet	yet	RB
cord-285180-32bxx94u	238	12	to	to	TO
cord-285180-32bxx94u	238	13	be	be	VB
cord-285180-32bxx94u	238	14	confirmed	confirm	VBN
cord-285180-32bxx94u	238	15	using	use	VBG
cord-285180-32bxx94u	238	16	an	an	DT
cord-285180-32bxx94u	238	17	authentic	authentic	JJ
cord-285180-32bxx94u	238	18	N	n	CD
cord-285180-32bxx94u	238	19	protein	protein	NN
cord-285180-32bxx94u	238	20	in	in	IN
cord-285180-32bxx94u	238	21	PDCoVinfected	PDCoVinfected	NNP
cord-285180-32bxx94u	238	22	cells	cell	NNS
cord-285180-32bxx94u	238	23	,	,	,
cord-285180-32bxx94u	238	24	but	but	CC
cord-285180-32bxx94u	238	25	according	accord	VBG
cord-285180-32bxx94u	238	26	to	to	IN
cord-285180-32bxx94u	238	27	our	-PRON-	PRP$
cord-285180-32bxx94u	238	28	results	result	NNS
cord-285180-32bxx94u	238	29	,	,	,
cord-285180-32bxx94u	238	30	PDCoV	pdcov	NN
cord-285180-32bxx94u	238	31	N	n	NN
cord-285180-32bxx94u	238	32	appears	appear	VBZ
cord-285180-32bxx94u	238	33	to	to	TO
cord-285180-32bxx94u	238	34	act	act	VB
cord-285180-32bxx94u	238	35	as	as	IN
cord-285180-32bxx94u	238	36	a	a	DT
cord-285180-32bxx94u	238	37	multifunctional	multifunctional	JJ
cord-285180-32bxx94u	238	38	protein	protein	NN
cord-285180-32bxx94u	238	39	playing	play	VBG
cord-285180-32bxx94u	238	40	structural	structural	JJ
cord-285180-32bxx94u	238	41	and	and	CC
cord-285180-32bxx94u	238	42	non	non	JJ
cord-285180-32bxx94u	238	43	-	-	JJ
cord-285180-32bxx94u	238	44	structural	structural	JJ
cord-285180-32bxx94u	238	45	roles	role	NNS
cord-285180-32bxx94u	238	46	contributing	contribute	VBG
cord-285180-32bxx94u	238	47	to	to	IN
cord-285180-32bxx94u	238	48	completion	completion	NN
cord-285180-32bxx94u	238	49	of	of	IN
cord-285180-32bxx94u	238	50	viral	viral	JJ
cord-285180-32bxx94u	238	51	replication	replication	NN
cord-285180-32bxx94u	238	52	.	.	.
cord-285180-32bxx94u	239	1	Our	-PRON-	PRP$
cord-285180-32bxx94u	239	2	proteomic	proteomic	JJ
cord-285180-32bxx94u	239	3	data	datum	NNS
cord-285180-32bxx94u	239	4	revealed	reveal	VBD
cord-285180-32bxx94u	239	5	that	that	IN
cord-285180-32bxx94u	239	6	10	10	CD
cord-285180-32bxx94u	239	7	differentially	differentially	RB
cord-285180-32bxx94u	239	8	expressed	express	VBN
cord-285180-32bxx94u	239	9	cellular	cellular	JJ
cord-285180-32bxx94u	239	10	proteins	protein	NNS
cord-285180-32bxx94u	239	11	are	be	VBP
cord-285180-32bxx94u	239	12	identifiable	identifiable	JJ
cord-285180-32bxx94u	239	13	in	in	IN
cord-285180-32bxx94u	239	14	PDCoV	pdcov	NN
cord-285180-32bxx94u	239	15	N	n	CD
cord-285180-32bxx94u	239	16	gene	gene	NN
cord-285180-32bxx94u	239	17	-	-	HYPH
cord-285180-32bxx94u	239	18	expressing	express	VBG
cord-285180-32bxx94u	239	19	porcine	porcine	JJ
cord-285180-32bxx94u	239	20	cells	cell	NNS
cord-285180-32bxx94u	239	21	.	.	.
cord-285180-32bxx94u	240	1	The	the	DT
cord-285180-32bxx94u	240	2	proteins	protein	NNS
cord-285180-32bxx94u	240	3	that	that	WDT
cord-285180-32bxx94u	240	4	we	-PRON-	PRP
cord-285180-32bxx94u	240	5	identified	identify	VBD
cord-285180-32bxx94u	240	6	in	in	IN
cord-285180-32bxx94u	240	7	this	this	DT
cord-285180-32bxx94u	240	8	study	study	NN
cord-285180-32bxx94u	240	9	are	be	VBP
cord-285180-32bxx94u	240	10	involved	involve	VBN
cord-285180-32bxx94u	240	11	in	in	IN
cord-285180-32bxx94u	240	12	diverse	diverse	JJ
cord-285180-32bxx94u	240	13	cellular	cellular	JJ
cord-285180-32bxx94u	240	14	processes	process	NNS
cord-285180-32bxx94u	240	15	:	:	:
cord-285180-32bxx94u	240	16	metabolism	metabolism	NN
cord-285180-32bxx94u	240	17	,	,	,
cord-285180-32bxx94u	240	18	the	the	DT
cord-285180-32bxx94u	240	19	stress	stress	NN
cord-285180-32bxx94u	240	20	response	response	NN
cord-285180-32bxx94u	240	21	,	,	,
cord-285180-32bxx94u	240	22	protein	protein	NN
cord-285180-32bxx94u	240	23	biosynthesis	biosynthesis	NN
cord-285180-32bxx94u	240	24	and	and	CC
cord-285180-32bxx94u	240	25	transport	transport	NN
cord-285180-32bxx94u	240	26	,	,	,
cord-285180-32bxx94u	240	27	cytoskeleton	cytoskeleton	NN
cord-285180-32bxx94u	240	28	networks	network	NNS
cord-285180-32bxx94u	240	29	and	and	CC
cord-285180-32bxx94u	240	30	cell	cell	NN
cord-285180-32bxx94u	240	31	communication	communication	NN
cord-285180-32bxx94u	240	32	,	,	,
cord-285180-32bxx94u	240	33	and	and	CC
cord-285180-32bxx94u	240	34	cell	cell	NN
cord-285180-32bxx94u	240	35	division	division	NN
cord-285180-32bxx94u	240	36	.	.	.
cord-285180-32bxx94u	241	1	The	the	DT
cord-285180-32bxx94u	241	2	significance	significance	NN
cord-285180-32bxx94u	241	3	of	of	IN
cord-285180-32bxx94u	241	4	the	the	DT
cord-285180-32bxx94u	241	5	functional	functional	JJ
cord-285180-32bxx94u	241	6	roles	role	NNS
cord-285180-32bxx94u	241	7	of	of	IN
cord-285180-32bxx94u	241	8	the	the	DT
cord-285180-32bxx94u	241	9	selected	select	VBN
cord-285180-32bxx94u	241	10	host	host	NN
cord-285180-32bxx94u	241	11	proteins	protein	NNS
cord-285180-32bxx94u	241	12	affected	affect	VBN
cord-285180-32bxx94u	241	13	by	by	IN
cord-285180-32bxx94u	241	14	the	the	DT
cord-285180-32bxx94u	241	15	interaction	interaction	NN
cord-285180-32bxx94u	241	16	of	of	IN
cord-285180-32bxx94u	241	17	the	the	DT
cord-285180-32bxx94u	241	18	PDCoV	pdcov	NN
cord-285180-32bxx94u	241	19	N	n	CD
cord-285180-32bxx94u	241	20	protein	protein	NN
cord-285180-32bxx94u	241	21	with	with	IN
cord-285180-32bxx94u	241	22	the	the	DT
cord-285180-32bxx94u	241	23	host	host	NN
cord-285180-32bxx94u	241	24	cell	cell	NN
cord-285180-32bxx94u	241	25	is	be	VBZ
cord-285180-32bxx94u	241	26	discussed	discuss	VBN
cord-285180-32bxx94u	241	27	below	below	RB
cord-285180-32bxx94u	241	28	.	.	.
cord-285180-32bxx94u	242	1	The	the	DT
cord-285180-32bxx94u	242	2	most	most	RBS
cord-285180-32bxx94u	242	3	interesting	interesting	JJ
cord-285180-32bxx94u	242	4	finding	finding	NN
cord-285180-32bxx94u	242	5	in	in	IN
cord-285180-32bxx94u	242	6	the	the	DT
cord-285180-32bxx94u	242	7	present	present	JJ
cord-285180-32bxx94u	242	8	study	study	NN
cord-285180-32bxx94u	242	9	is	be	VBZ
cord-285180-32bxx94u	242	10	that	that	IN
cord-285180-32bxx94u	242	11	two	two	CD
cord-285180-32bxx94u	242	12	cellular	cellular	JJ
cord-285180-32bxx94u	242	13	chaperone	chaperone	NN
cord-285180-32bxx94u	242	14	proteins	protein	NNS
cord-285180-32bxx94u	242	15	belonging	belong	VBG
cord-285180-32bxx94u	242	16	to	to	IN
cord-285180-32bxx94u	242	17	the	the	DT
cord-285180-32bxx94u	242	18	HSP70	HSP70	NNP
cord-285180-32bxx94u	242	19	family	family	NN
cord-285180-32bxx94u	242	20	are	be	VBP
cord-285180-32bxx94u	242	21	up	up	RB
cord-285180-32bxx94u	242	22	-	-	HYPH
cord-285180-32bxx94u	242	23	regulated	regulate	VBN
cord-285180-32bxx94u	242	24	concomitantly	concomitantly	RB
cord-285180-32bxx94u	242	25	by	by	IN
cord-285180-32bxx94u	242	26	the	the	DT
cord-285180-32bxx94u	242	27	N	n	CD
cord-285180-32bxx94u	242	28	protein	protein	NN
cord-285180-32bxx94u	242	29	of	of	IN
cord-285180-32bxx94u	242	30	PDCoV.	pdcov.	NN
cord-285180-32bxx94u	243	1	The	the	DT
cord-285180-32bxx94u	243	2	first	first	JJ
cord-285180-32bxx94u	243	3	up	up	RB
cord-285180-32bxx94u	243	4	-	-	HYPH
cord-285180-32bxx94u	243	5	regulated	regulated	JJ
cord-285180-32bxx94u	243	6	protein	protein	NN
cord-285180-32bxx94u	243	7	is	be	VBZ
cord-285180-32bxx94u	243	8	GRP78	GRP78	NNP
cord-285180-32bxx94u	243	9	in	in	IN
cord-285180-32bxx94u	243	10	cells	cell	NNS
cord-285180-32bxx94u	243	11	expressing	express	VBG
cord-285180-32bxx94u	243	12	the	the	DT
cord-285180-32bxx94u	243	13	PDCoV	pdcov	NN
cord-285180-32bxx94u	243	14	N	n	CD
cord-285180-32bxx94u	243	15	protein	protein	NN
cord-285180-32bxx94u	243	16	,	,	,
cord-285180-32bxx94u	243	17	which	which	WDT
cord-285180-32bxx94u	243	18	is	be	VBZ
cord-285180-32bxx94u	243	19	associated	associate	VBN
cord-285180-32bxx94u	243	20	with	with	IN
cord-285180-32bxx94u	243	21	endoplasmic	endoplasmic	NN
cord-285180-32bxx94u	243	22	reticulum	reticulum	NN
cord-285180-32bxx94u	243	23	(	(	-LRB-
cord-285180-32bxx94u	243	24	ER	ER	NNP
cord-285180-32bxx94u	243	25	)	)	-RRB-
cord-285180-32bxx94u	243	26	stress	stress	NN
cord-285180-32bxx94u	243	27	.	.	.
cord-285180-32bxx94u	244	1	In	in	IN
cord-285180-32bxx94u	244	2	eukaryotic	eukaryotic	JJ
cord-285180-32bxx94u	244	3	cells	cell	NNS
cord-285180-32bxx94u	244	4	,	,	,
cord-285180-32bxx94u	244	5	the	the	DT
cord-285180-32bxx94u	244	6	ER	ER	NNP
cord-285180-32bxx94u	244	7	is	be	VBZ
cord-285180-32bxx94u	244	8	the	the	DT
cord-285180-32bxx94u	244	9	major	major	JJ
cord-285180-32bxx94u	244	10	site	site	NN
cord-285180-32bxx94u	244	11	for	for	IN
cord-285180-32bxx94u	244	12	synthesis	synthesis	NN
cord-285180-32bxx94u	244	13	and	and	CC
cord-285180-32bxx94u	244	14	folding	folding	NN
cord-285180-32bxx94u	244	15	of	of	IN
cord-285180-32bxx94u	244	16	transmembrane	transmembrane	NN
cord-285180-32bxx94u	244	17	and	and	CC
cord-285180-32bxx94u	244	18	secreted	secrete	VBN
cord-285180-32bxx94u	244	19	proteins	protein	NNS
cord-285180-32bxx94u	244	20	,	,	,
cord-285180-32bxx94u	244	21	and	and	CC
cord-285180-32bxx94u	244	22	accordingly	accordingly	RB
cord-285180-32bxx94u	244	23	,	,	,
cord-285180-32bxx94u	244	24	animal	animal	NN
cord-285180-32bxx94u	244	25	viruses	virus	NNS
cord-285180-32bxx94u	244	26	also	also	RB
cord-285180-32bxx94u	244	27	use	use	VBP
cord-285180-32bxx94u	244	28	the	the	DT
cord-285180-32bxx94u	244	29	ER	ER	NNP
cord-285180-32bxx94u	244	30	as	as	IN
cord-285180-32bxx94u	244	31	a	a	DT
cord-285180-32bxx94u	244	32	site	site	NN
cord-285180-32bxx94u	244	33	of	of	IN
cord-285180-32bxx94u	244	34	synthesis	synthesis	NN
cord-285180-32bxx94u	244	35	and	and	CC
cord-285180-32bxx94u	244	36	processing	processing	NN
cord-285180-32bxx94u	244	37	of	of	IN
cord-285180-32bxx94u	244	38	their	-PRON-	PRP$
cord-285180-32bxx94u	244	39	own	own	JJ
cord-285180-32bxx94u	244	40	proteins	protein	NNS
cord-285180-32bxx94u	244	41	.	.	.
cord-285180-32bxx94u	245	1	The	the	DT
cord-285180-32bxx94u	245	2	amount	amount	NN
cord-285180-32bxx94u	245	3	of	of	IN
cord-285180-32bxx94u	245	4	protein	protein	NN
cord-285180-32bxx94u	245	5	entering	enter	VBG
cord-285180-32bxx94u	245	6	the	the	DT
cord-285180-32bxx94u	245	7	ER	ER	NNP
cord-285180-32bxx94u	245	8	can	can	MD
cord-285180-32bxx94u	245	9	differ	differ	VB
cord-285180-32bxx94u	245	10	under	under	IN
cord-285180-32bxx94u	245	11	physiological	physiological	JJ
cord-285180-32bxx94u	245	12	and	and	CC
cord-285180-32bxx94u	245	13	environmental	environmental	JJ
cord-285180-32bxx94u	245	14	conditions	condition	NNS
cord-285180-32bxx94u	245	15	.	.	.
cord-285180-32bxx94u	246	1	If	if	IN
cord-285180-32bxx94u	246	2	protein	protein	NN
cord-285180-32bxx94u	246	3	synthesis	synthesis	NN
cord-285180-32bxx94u	246	4	exceeds	exceed	VBZ
cord-285180-32bxx94u	246	5	the	the	DT
cord-285180-32bxx94u	246	6	folding	folding	NN
cord-285180-32bxx94u	246	7	capacity	capacity	NN
cord-285180-32bxx94u	246	8	of	of	IN
cord-285180-32bxx94u	246	9	the	the	DT
cord-285180-32bxx94u	246	10	ER	ER	NNP
cord-285180-32bxx94u	246	11	,	,	,
cord-285180-32bxx94u	246	12	unfolded	unfold	VBD
cord-285180-32bxx94u	246	13	proteins	protein	NNS
cord-285180-32bxx94u	246	14	accumulate	accumulate	VBP
cord-285180-32bxx94u	246	15	there	there	RB
cord-285180-32bxx94u	246	16	,	,	,
cord-285180-32bxx94u	246	17	resulting	result	VBG
cord-285180-32bxx94u	246	18	in	in	IN
cord-285180-32bxx94u	246	19	ER	ER	NNP
cord-285180-32bxx94u	246	20	stress	stress	NN
cord-285180-32bxx94u	246	21	.	.	.
cord-285180-32bxx94u	247	1	To	to	TO
cord-285180-32bxx94u	247	2	maintain	maintain	VB
cord-285180-32bxx94u	247	3	the	the	DT
cord-285180-32bxx94u	247	4	ER	ER	NNP
cord-285180-32bxx94u	247	5	homeostasis	homeostasis	NN
cord-285180-32bxx94u	247	6	,	,	,
cord-285180-32bxx94u	247	7	cells	cell	NNS
cord-285180-32bxx94u	247	8	have	have	VBP
cord-285180-32bxx94u	247	9	developed	develop	VBN
cord-285180-32bxx94u	247	10	a	a	DT
cord-285180-32bxx94u	247	11	signaling	signal	VBG
cord-285180-32bxx94u	247	12	pathway	pathway	NN
cord-285180-32bxx94u	247	13	known	know	VBN
cord-285180-32bxx94u	247	14	as	as	IN
cord-285180-32bxx94u	247	15	the	the	DT
cord-285180-32bxx94u	247	16	unfolded	unfolded	JJ
cord-285180-32bxx94u	247	17	protein	protein	NN
cord-285180-32bxx94u	247	18	response	response	NN
cord-285180-32bxx94u	247	19	(	(	-LRB-
cord-285180-32bxx94u	247	20	UPR	UPR	NNP
cord-285180-32bxx94u	247	21	)	)	-RRB-
cord-285180-32bxx94u	247	22	that	that	WDT
cord-285180-32bxx94u	247	23	transmits	transmit	VBZ
cord-285180-32bxx94u	247	24	signals	signal	NNS
cord-285180-32bxx94u	247	25	across	across	IN
cord-285180-32bxx94u	247	26	the	the	DT
cord-285180-32bxx94u	247	27	ER	ER	NNP
cord-285180-32bxx94u	247	28	membrane	membrane	NN
cord-285180-32bxx94u	247	29	to	to	IN
cord-285180-32bxx94u	247	30	the	the	DT
cord-285180-32bxx94u	247	31	cytosol	cytosol	NN
cord-285180-32bxx94u	247	32	and	and	CC
cord-285180-32bxx94u	247	33	the	the	DT
cord-285180-32bxx94u	247	34	nucleus	nucleus	NN
cord-285180-32bxx94u	247	35	and	and	CC
cord-285180-32bxx94u	247	36	ultimately	ultimately	RB
cord-285180-32bxx94u	247	37	reduces	reduce	VBZ
cord-285180-32bxx94u	247	38	protein	protein	NN
cord-285180-32bxx94u	247	39	translation	translation	NN
cord-285180-32bxx94u	247	40	and	and	CC
cord-285180-32bxx94u	247	41	enhances	enhance	VBZ
cord-285180-32bxx94u	247	42	the	the	DT
cord-285180-32bxx94u	247	43	ER	ER	NNP
cord-285180-32bxx94u	247	44	folding	folding	NN
cord-285180-32bxx94u	247	45	capacity	capacity	NN
cord-285180-32bxx94u	247	46	by	by	IN
cord-285180-32bxx94u	247	47	up	up	IN
cord-285180-32bxx94u	247	48	-	-	HYPH
cord-285180-32bxx94u	247	49	regulating	regulate	VBG
cord-285180-32bxx94u	247	50	chaperone	chaperone	NN
cord-285180-32bxx94u	247	51	proteins	protein	NNS
cord-285180-32bxx94u	247	52	(	(	-LRB-
cord-285180-32bxx94u	247	53	Ron	Ron	NNP
cord-285180-32bxx94u	247	54	and	and	CC
cord-285180-32bxx94u	247	55	Walter	Walter	NNP
cord-285180-32bxx94u	247	56	,	,	,
cord-285180-32bxx94u	247	57	2007	2007	CD
cord-285180-32bxx94u	247	58	)	)	-RRB-
cord-285180-32bxx94u	247	59	.	.	.
cord-285180-32bxx94u	248	1	Coronavirus	Coronavirus	NNP
cord-285180-32bxx94u	248	2	infection	infection	NN
cord-285180-32bxx94u	248	3	of	of	IN
cord-285180-32bxx94u	248	4	cultured	cultured	JJ
cord-285180-32bxx94u	248	5	cells	cell	NNS
cord-285180-32bxx94u	248	6	is	be	VBZ
cord-285180-32bxx94u	248	7	known	know	VBN
cord-285180-32bxx94u	248	8	to	to	TO
cord-285180-32bxx94u	248	9	cause	cause	VB
cord-285180-32bxx94u	248	10	ER	ER	NNP
cord-285180-32bxx94u	248	11	stress	stress	NN
cord-285180-32bxx94u	248	12	and	and	CC
cord-285180-32bxx94u	248	13	to	to	TO
cord-285180-32bxx94u	248	14	induce	induce	VB
cord-285180-32bxx94u	248	15	the	the	DT
cord-285180-32bxx94u	248	16	UPR	UPR	NNP
cord-285180-32bxx94u	248	17	,	,	,
cord-285180-32bxx94u	248	18	which	which	WDT
cord-285180-32bxx94u	248	19	then	then	RB
cord-285180-32bxx94u	248	20	crosstalks	crosstalk	VBZ
cord-285180-32bxx94u	248	21	with	with	IN
cord-285180-32bxx94u	248	22	various	various	JJ
cord-285180-32bxx94u	248	23	cellular	cellular	JJ
cord-285180-32bxx94u	248	24	signaling	signal	VBG
cord-285180-32bxx94u	248	25	pathways	pathway	NNS
cord-285180-32bxx94u	248	26	,	,	,
cord-285180-32bxx94u	248	27	including	include	VBG
cord-285180-32bxx94u	248	28	mitogen	mitogen	NN
cord-285180-32bxx94u	248	29	-	-	HYPH
cord-285180-32bxx94u	248	30	activated	activate	VBN
cord-285180-32bxx94u	248	31	protein	protein	NN
cord-285180-32bxx94u	248	32	kinase	kinase	NN
cord-285180-32bxx94u	248	33	cascades	cascade	NNS
cord-285180-32bxx94u	248	34	,	,	,
cord-285180-32bxx94u	248	35	autophagy	autophagy	NN
cord-285180-32bxx94u	248	36	,	,	,
cord-285180-32bxx94u	248	37	apoptosis	apoptosis	NN
cord-285180-32bxx94u	248	38	,	,	,
cord-285180-32bxx94u	248	39	and	and	CC
cord-285180-32bxx94u	248	40	innate	innate	VB
cord-285180-32bxx94u	248	41	immune	immune	JJ
cord-285180-32bxx94u	248	42	responses	response	NNS
cord-285180-32bxx94u	248	43	,	,	,
cord-285180-32bxx94u	248	44	indicating	indicate	VBG
cord-285180-32bxx94u	248	45	the	the	DT
cord-285180-32bxx94u	248	46	involvement	involvement	NN
cord-285180-32bxx94u	248	47	of	of	IN
cord-285180-32bxx94u	248	48	UPR	UPR	NNP
cord-285180-32bxx94u	248	49	activation	activation	NN
cord-285180-32bxx94u	248	50	in	in	IN
cord-285180-32bxx94u	248	51	virus	virus	NN
cord-285180-32bxx94u	248	52	-	-	HYPH
cord-285180-32bxx94u	248	53	host	host	NN
cord-285180-32bxx94u	248	54	interactions	interaction	NNS
cord-285180-32bxx94u	248	55	and	and	CC
cord-285180-32bxx94u	248	56	viral	viral	JJ
cord-285180-32bxx94u	248	57	pathogenesis	pathogenesis	NN
cord-285180-32bxx94u	248	58	.	.	.
cord-285180-32bxx94u	249	1	More	more	RBR
cord-285180-32bxx94u	249	2	interestingly	interestingly	RB
cord-285180-32bxx94u	249	3	,	,	,
cord-285180-32bxx94u	249	4	global	global	JJ
cord-285180-32bxx94u	249	5	proteomic	proteomic	NN
cord-285180-32bxx94u	249	6	and	and	CC
cord-285180-32bxx94u	249	7	microarray	microarray	NN
cord-285180-32bxx94u	249	8	analyses	analysis	NNS
cord-285180-32bxx94u	249	9	have	have	VBP
cord-285180-32bxx94u	249	10	shown	show	VBN
cord-285180-32bxx94u	249	11	that	that	IN
cord-285180-32bxx94u	249	12	the	the	DT
cord-285180-32bxx94u	249	13	expression	expression	NN
cord-285180-32bxx94u	249	14	of	of	IN
cord-285180-32bxx94u	249	15	chaperon	chaperon	NN
cord-285180-32bxx94u	249	16	proteins	protein	NNS
cord-285180-32bxx94u	249	17	,	,	,
cord-285180-32bxx94u	249	18	such	such	JJ
cord-285180-32bxx94u	249	19	as	as	IN
cord-285180-32bxx94u	249	20	GRP78	GRP78	NNP
cord-285180-32bxx94u	249	21	and	and	CC
cord-285180-32bxx94u	249	22	GRP94	GRP94	NNP
cord-285180-32bxx94u	249	23	,	,	,
cord-285180-32bxx94u	249	24	is	be	VBZ
cord-285180-32bxx94u	249	25	up	up	RB
cord-285180-32bxx94u	249	26	-	-	HYPH
cord-285180-32bxx94u	249	27	regulated	regulate	VBN
cord-285180-32bxx94u	249	28	in	in	IN
cord-285180-32bxx94u	249	29	cells	cell	NNS
cord-285180-32bxx94u	249	30	infected	infect	VBN
cord-285180-32bxx94u	249	31	with	with	IN
cord-285180-32bxx94u	249	32	a	a	DT
cord-285180-32bxx94u	249	33	human	human	JJ
cord-285180-32bxx94u	249	34	coronavirus	coronavirus	NN
cord-285180-32bxx94u	249	35	or	or	CC
cord-285180-32bxx94u	249	36	in	in	IN
cord-285180-32bxx94u	249	37	cells	cell	NNS
cord-285180-32bxx94u	249	38	expressing	express	VBG
cord-285180-32bxx94u	249	39	the	the	DT
cord-285180-32bxx94u	249	40	S2	S2	NNP
cord-285180-32bxx94u	249	41	subunit	subunit	NN
cord-285180-32bxx94u	249	42	(	(	-LRB-
cord-285180-32bxx94u	249	43	Jiang	Jiang	NNP
cord-285180-32bxx94u	249	44	et	et	FW
cord-285180-32bxx94u	249	45	al	al	NNP
cord-285180-32bxx94u	249	46	.	.	NNP
cord-285180-32bxx94u	249	47	,	,	,
cord-285180-32bxx94u	249	48	2005	2005	CD
cord-285180-32bxx94u	249	49	;	;	:
cord-285180-32bxx94u	249	50	Yeung	Yeung	NNP
cord-285180-32bxx94u	249	51	et	et	NNP
cord-285180-32bxx94u	249	52	al	al	NNP
cord-285180-32bxx94u	249	53	.	.	NNP
cord-285180-32bxx94u	249	54	,	,	,
cord-285180-32bxx94u	249	55	2008	2008	CD
cord-285180-32bxx94u	249	56	)	)	-RRB-
cord-285180-32bxx94u	249	57	.	.	.
cord-285180-32bxx94u	250	1	Furthermore	furthermore	RB
cord-285180-32bxx94u	250	2	,	,	,
cord-285180-32bxx94u	250	3	the	the	DT
cord-285180-32bxx94u	250	4	N	n	CD
cord-285180-32bxx94u	250	5	protein	protein	NN
cord-285180-32bxx94u	250	6	of	of	IN
cord-285180-32bxx94u	250	7	PEDV	PEDV	NNP
cord-285180-32bxx94u	250	8	,	,	,
cord-285180-32bxx94u	250	9	another	another	DT
cord-285180-32bxx94u	250	10	porcine	porcine	JJ
cord-285180-32bxx94u	250	11	coronavirus	coronavirus	NN
cord-285180-32bxx94u	250	12	,	,	,
cord-285180-32bxx94u	250	13	overexpression	overexpression	NN
cord-285180-32bxx94u	250	14	was	be	VBD
cord-285180-32bxx94u	250	15	shown	show	VBN
cord-285180-32bxx94u	250	16	to	to	TO
cord-285180-32bxx94u	250	17	trigger	trigger	VB
cord-285180-32bxx94u	250	18	ER	ER	NNP
cord-285180-32bxx94u	250	19	stress	stress	NN
cord-285180-32bxx94u	250	20	(	(	-LRB-
cord-285180-32bxx94u	250	21	Xu	Xu	NNP
cord-285180-32bxx94u	250	22	et	et	NNP
cord-285180-32bxx94u	250	23	al	al	NNP
cord-285180-32bxx94u	250	24	.	.	NNP
cord-285180-32bxx94u	250	25	,	,	,
cord-285180-32bxx94u	250	26	2013	2013	CD
cord-285180-32bxx94u	250	27	)	)	-RRB-
cord-285180-32bxx94u	250	28	.	.	.
cord-285180-32bxx94u	251	1	Thus	thus	RB
cord-285180-32bxx94u	251	2	,	,	,
cord-285180-32bxx94u	251	3	it	-PRON-	PRP
cord-285180-32bxx94u	251	4	appears	appear	VBZ
cord-285180-32bxx94u	251	5	that	that	IN
cord-285180-32bxx94u	251	6	PDCoV	pdcov	JJ
cord-285180-32bxx94u	251	7	infection	infection	NN
cord-285180-32bxx94u	251	8	may	may	MD
cord-285180-32bxx94u	251	9	induce	induce	VB
cord-285180-32bxx94u	251	10	ER	ER	NNP
cord-285180-32bxx94u	251	11	stress	stress	NN
cord-285180-32bxx94u	251	12	and	and	CC
cord-285180-32bxx94u	251	13	the	the	DT
cord-285180-32bxx94u	251	14	UPR	UPR	NNP
cord-285180-32bxx94u	251	15	,	,	,
cord-285180-32bxx94u	251	16	leading	lead	VBG
cord-285180-32bxx94u	251	17	to	to	IN
cord-285180-32bxx94u	251	18	the	the	DT
cord-285180-32bxx94u	251	19	up	up	JJ
cord-285180-32bxx94u	251	20	-	-	HYPH
cord-285180-32bxx94u	251	21	regulation	regulation	NN
cord-285180-32bxx94u	251	22	of	of	IN
cord-285180-32bxx94u	251	23	GRP78	GRP78	NNP
cord-285180-32bxx94u	251	24	to	to	TO
cord-285180-32bxx94u	251	25	counteract	counteract	VB
cord-285180-32bxx94u	251	26	the	the	DT
cord-285180-32bxx94u	251	27	ER	ER	NNP
cord-285180-32bxx94u	251	28	stress	stress	NN
cord-285180-32bxx94u	251	29	;	;	:
cord-285180-32bxx94u	251	30	hence	hence	RB
cord-285180-32bxx94u	251	31	,	,	,
cord-285180-32bxx94u	251	32	the	the	DT
cord-285180-32bxx94u	251	33	N	n	CD
cord-285180-32bxx94u	251	34	protein	protein	NN
cord-285180-32bxx94u	251	35	may	may	MD
cord-285180-32bxx94u	251	36	be	be	VB
cord-285180-32bxx94u	251	37	responsible	responsible	JJ
cord-285180-32bxx94u	251	38	for	for	IN
cord-285180-32bxx94u	251	39	this	this	DT
cord-285180-32bxx94u	251	40	stress	stress	NN
cord-285180-32bxx94u	251	41	response	response	NN
cord-285180-32bxx94u	251	42	pathway	pathway	NN
cord-285180-32bxx94u	251	43	.	.	.
cord-285180-32bxx94u	252	1	The	the	DT
cord-285180-32bxx94u	252	2	second	second	JJ
cord-285180-32bxx94u	252	3	identified	identify	VBD
cord-285180-32bxx94u	252	4	HSP70	HSP70	NNP
cord-285180-32bxx94u	252	5	family	family	NN
cord-285180-32bxx94u	252	6	protein	protein	NN
cord-285180-32bxx94u	252	7	is	be	VBZ
cord-285180-32bxx94u	252	8	HSC70	HSC70	NNP
cord-285180-32bxx94u	252	9	,	,	,
cord-285180-32bxx94u	252	10	also	also	RB
cord-285180-32bxx94u	252	11	known	know	VBN
cord-285180-32bxx94u	252	12	as	as	IN
cord-285180-32bxx94u	252	13	heat	heat	NN
cord-285180-32bxx94u	252	14	shock	shock	NN
cord-285180-32bxx94u	252	15	70-kDa	70-kda	CD
cord-285180-32bxx94u	252	16	protein	protein	NN
cord-285180-32bxx94u	252	17	8	8	CD
cord-285180-32bxx94u	252	18	(	(	-LRB-
cord-285180-32bxx94u	252	19	HSPA8	HSPA8	NNP
cord-285180-32bxx94u	252	20	)	)	-RRB-
cord-285180-32bxx94u	252	21	.	.	.
cord-285180-32bxx94u	253	1	HSC70	HSC70	NNP
cord-285180-32bxx94u	253	2	is	be	VBZ
cord-285180-32bxx94u	253	3	a	a	DT
cord-285180-32bxx94u	253	4	molecular	molecular	JJ
cord-285180-32bxx94u	253	5	chaperone	chaperone	NN
cord-285180-32bxx94u	253	6	with	with	IN
cord-285180-32bxx94u	253	7	multiple	multiple	JJ
cord-285180-32bxx94u	253	8	functions	function	NNS
cord-285180-32bxx94u	253	9	in	in	IN
cord-285180-32bxx94u	253	10	protein	protein	NN
cord-285180-32bxx94u	253	11	folding	folding	NN
cord-285180-32bxx94u	253	12	and	and	CC
cord-285180-32bxx94u	253	13	trafficking	trafficking	NN
cord-285180-32bxx94u	253	14	in	in	IN
cord-285180-32bxx94u	253	15	all	all	DT
cord-285180-32bxx94u	253	16	eukaryotic	eukaryotic	JJ
cord-285180-32bxx94u	253	17	cells	cell	NNS
cord-285180-32bxx94u	253	18	and	and	CC
cord-285180-32bxx94u	253	19	in	in	IN
cord-285180-32bxx94u	253	20	protecting	protect	VBG
cord-285180-32bxx94u	253	21	cells	cell	NNS
cord-285180-32bxx94u	253	22	from	from	IN
cord-285180-32bxx94u	253	23	apoptosis	apoptosis	NN
cord-285180-32bxx94u	253	24	or	or	CC
cord-285180-32bxx94u	253	25	a	a	DT
cord-285180-32bxx94u	253	26	wide	wide	JJ
cord-285180-32bxx94u	253	27	array	array	NN
cord-285180-32bxx94u	253	28	of	of	IN
cord-285180-32bxx94u	253	29	stressors	stressor	NNS
cord-285180-32bxx94u	253	30	such	such	JJ
cord-285180-32bxx94u	253	31	as	as	IN
cord-285180-32bxx94u	253	32	heat	heat	NN
cord-285180-32bxx94u	253	33	and	and	CC
cord-285180-32bxx94u	253	34	infection	infection	NN
cord-285180-32bxx94u	253	35	(	(	-LRB-
cord-285180-32bxx94u	253	36	Morano	Morano	NNP
cord-285180-32bxx94u	253	37	,	,	,
cord-285180-32bxx94u	253	38	2007	2007	CD
cord-285180-32bxx94u	253	39	;	;	.
cord-285180-32bxx94u	254	1	Powers	power	NNS
cord-285180-32bxx94u	254	2	et	et	NNP
cord-285180-32bxx94u	254	3	al	al	NNP
cord-285180-32bxx94u	254	4	.	.	NNP
cord-285180-32bxx94u	254	5	,	,	,
cord-285180-32bxx94u	254	6	2008	2008	CD
cord-285180-32bxx94u	255	1	;	;	:
cord-285180-32bxx94u	255	2	Takayama	Takayama	NNP
cord-285180-32bxx94u	255	3	et	et	NNP
cord-285180-32bxx94u	255	4	al	al	NNP
cord-285180-32bxx94u	255	5	.	.	NNP
cord-285180-32bxx94u	255	6	,	,	,
cord-285180-32bxx94u	255	7	1999	1999	CD
cord-285180-32bxx94u	255	8	)	)	-RRB-
cord-285180-32bxx94u	255	9	.	.	.
cord-285180-32bxx94u	256	1	Accumulating	accumulate	VBG
cord-285180-32bxx94u	256	2	evidence	evidence	NN
cord-285180-32bxx94u	256	3	has	have	VBZ
cord-285180-32bxx94u	256	4	shown	show	VBN
cord-285180-32bxx94u	256	5	that	that	IN
cord-285180-32bxx94u	256	6	HSC70	HSC70	NNP
cord-285180-32bxx94u	256	7	plays	play	VBZ
cord-285180-32bxx94u	256	8	important	important	JJ
cord-285180-32bxx94u	256	9	roles	role	NNS
cord-285180-32bxx94u	256	10	in	in	IN
cord-285180-32bxx94u	256	11	certain	certain	JJ
cord-285180-32bxx94u	256	12	processes	process	NNS
cord-285180-32bxx94u	256	13	involved	involve	VBN
cord-285180-32bxx94u	256	14	in	in	IN
cord-285180-32bxx94u	256	15	viral	viral	JJ
cord-285180-32bxx94u	256	16	infection	infection	NN
cord-285180-32bxx94u	256	17	by	by	IN
cord-285180-32bxx94u	256	18	modulating	modulate	VBG
cord-285180-32bxx94u	256	19	cell	cell	NN
cord-285180-32bxx94u	256	20	entry	entry	NN
cord-285180-32bxx94u	256	21	,	,	,
cord-285180-32bxx94u	256	22	virion	virion	NN
cord-285180-32bxx94u	256	23	disassembly	disassembly	NN
cord-285180-32bxx94u	256	24	and	and	CC
cord-285180-32bxx94u	256	25	assembly	assembly	NN
cord-285180-32bxx94u	256	26	,	,	,
cord-285180-32bxx94u	256	27	and	and	CC
cord-285180-32bxx94u	256	28	the	the	DT
cord-285180-32bxx94u	256	29	cellular	cellular	JJ
cord-285180-32bxx94u	256	30	antiviral	antiviral	JJ
cord-285180-32bxx94u	256	31	response	response	NN
cord-285180-32bxx94u	256	32	and	and	CC
cord-285180-32bxx94u	256	33	apoptosis	apoptosis	NN
cord-285180-32bxx94u	256	34	(	(	-LRB-
cord-285180-32bxx94u	256	35	Chuang	Chuang	NNP
cord-285180-32bxx94u	256	36	et	et	NNP
cord-285180-32bxx94u	256	37	al	al	NNP
cord-285180-32bxx94u	256	38	.	.	NNP
cord-285180-32bxx94u	256	39	,	,	,
cord-285180-32bxx94u	256	40	2015	2015	CD
cord-285180-32bxx94u	256	41	;	;	:
cord-285180-32bxx94u	256	42	Gutiérrez	Gutiérrez	NNP
cord-285180-32bxx94u	256	43	et	et	NNP
cord-285180-32bxx94u	256	44	al	al	NNP
cord-285180-32bxx94u	256	45	.	.	NNP
cord-285180-32bxx94u	256	46	,	,	,
cord-285180-32bxx94u	256	47	2010	2010	CD
cord-285180-32bxx94u	256	48	;	;	:
cord-285180-32bxx94u	256	49	Ivanovic	Ivanovic	NNP
cord-285180-32bxx94u	256	50	et	et	NNP
cord-285180-32bxx94u	256	51	al	al	NNP
cord-285180-32bxx94u	256	52	.	.	NNP
cord-285180-32bxx94u	256	53	,	,	,
cord-285180-32bxx94u	256	54	2007	2007	CD
cord-285180-32bxx94u	256	55	;	;	:
cord-285180-32bxx94u	256	56	Liu	Liu	NNP
cord-285180-32bxx94u	256	57	et	et	NNP
cord-285180-32bxx94u	256	58	al	al	NNP
cord-285180-32bxx94u	256	59	.	.	NNP
cord-285180-32bxx94u	256	60	,	,	,
cord-285180-32bxx94u	256	61	2013	2013	CD
cord-285180-32bxx94u	256	62	;	;	:
cord-285180-32bxx94u	256	63	Radhakrishnan	Radhakrishnan	NNP
cord-285180-32bxx94u	256	64	et	et	NNP
cord-285180-32bxx94u	256	65	al	al	NNP
cord-285180-32bxx94u	256	66	.	.	.
cord-285180-32bxx94u	257	1	,	,	,
cord-285180-32bxx94u	257	2	2010	2010	CD
cord-285180-32bxx94u	257	3	;	;	:
cord-285180-32bxx94u	257	4	Yan	Yan	NNP
cord-285180-32bxx94u	257	5	et	et	NNP
cord-285180-32bxx94u	257	6	al	al	NNP
cord-285180-32bxx94u	257	7	.	.	NNP
cord-285180-32bxx94u	257	8	,	,	,
cord-285180-32bxx94u	257	9	2010	2010	CD
cord-285180-32bxx94u	257	10	)	)	-RRB-
cord-285180-32bxx94u	257	11	.	.	.
cord-285180-32bxx94u	258	1	Apoptosis	apoptosis	NN
cord-285180-32bxx94u	258	2	is	be	VBZ
cord-285180-32bxx94u	258	3	considered	consider	VBN
cord-285180-32bxx94u	258	4	an	an	DT
cord-285180-32bxx94u	258	5	innate	innate	JJ
cord-285180-32bxx94u	258	6	defense	defense	NN
cord-285180-32bxx94u	258	7	mechanism	mechanism	NN
cord-285180-32bxx94u	258	8	that	that	WDT
cord-285180-32bxx94u	258	9	limits	limit	VBZ
cord-285180-32bxx94u	258	10	propagation	propagation	NN
cord-285180-32bxx94u	258	11	of	of	IN
cord-285180-32bxx94u	258	12	a	a	DT
cord-285180-32bxx94u	258	13	virus	virus	NN
cord-285180-32bxx94u	258	14	by	by	IN
cord-285180-32bxx94u	258	15	eliminating	eliminate	VBG
cord-285180-32bxx94u	258	16	infected	infected	JJ
cord-285180-32bxx94u	258	17	cells	cell	NNS
cord-285180-32bxx94u	258	18	(	(	-LRB-
cord-285180-32bxx94u	258	19	Everett	Everett	NNP
cord-285180-32bxx94u	258	20	and	and	CC
cord-285180-32bxx94u	258	21	McFadden	McFadden	NNP
cord-285180-32bxx94u	258	22	,	,	,
cord-285180-32bxx94u	258	23	1999	1999	CD
cord-285180-32bxx94u	258	24	)	)	-RRB-
cord-285180-32bxx94u	258	25	.	.	.
cord-285180-32bxx94u	259	1	Therefore	therefore	RB
cord-285180-32bxx94u	259	2	,	,	,
cord-285180-32bxx94u	259	3	many	many	JJ
cord-285180-32bxx94u	259	4	viruses	virus	NNS
cord-285180-32bxx94u	259	5	have	have	VBP
cord-285180-32bxx94u	259	6	evolved	evolve	VBN
cord-285180-32bxx94u	259	7	to	to	TO
cord-285180-32bxx94u	259	8	employ	employ	VB
cord-285180-32bxx94u	259	9	various	various	JJ
cord-285180-32bxx94u	259	10	strategies	strategy	NNS
cord-285180-32bxx94u	259	11	that	that	WDT
cord-285180-32bxx94u	259	12	inhibit	inhibit	VBP
cord-285180-32bxx94u	259	13	apoptosis	apoptosis	NN
cord-285180-32bxx94u	259	14	in	in	IN
cord-285180-32bxx94u	259	15	order	order	NN
cord-285180-32bxx94u	259	16	to	to	TO
cord-285180-32bxx94u	259	17	prevent	prevent	VB
cord-285180-32bxx94u	259	18	premature	premature	JJ
cord-285180-32bxx94u	259	19	cell	cell	NN
cord-285180-32bxx94u	259	20	death	death	NN
cord-285180-32bxx94u	259	21	,	,	,
cord-285180-32bxx94u	259	22	thereby	thereby	RB
cord-285180-32bxx94u	259	23	securing	secure	VBG
cord-285180-32bxx94u	259	24	sufficient	sufficient	JJ
cord-285180-32bxx94u	259	25	time	time	NN
cord-285180-32bxx94u	259	26	for	for	IN
cord-285180-32bxx94u	259	27	progeny	progeny	JJ
cord-285180-32bxx94u	259	28	production	production	NN
cord-285180-32bxx94u	259	29	.	.	.
cord-285180-32bxx94u	260	1	Thus	thus	RB
cord-285180-32bxx94u	260	2	,	,	,
cord-285180-32bxx94u	260	3	a	a	DT
cord-285180-32bxx94u	260	4	conceivable	conceivable	JJ
cord-285180-32bxx94u	260	5	explanation	explanation	NN
cord-285180-32bxx94u	260	6	is	be	VBZ
cord-285180-32bxx94u	260	7	that	that	IN
cord-285180-32bxx94u	260	8	PDCoV	pdcov	NN
cord-285180-32bxx94u	260	9	may	may	MD
cord-285180-32bxx94u	260	10	take	take	VB
cord-285180-32bxx94u	260	11	the	the	DT
cord-285180-32bxx94u	260	12	advantage	advantage	NN
cord-285180-32bxx94u	260	13	of	of	IN
cord-285180-32bxx94u	260	14	suppressing	suppress	VBG
cord-285180-32bxx94u	260	15	apoptosis	apoptosis	NN
cord-285180-32bxx94u	260	16	by	by	IN
cord-285180-32bxx94u	260	17	up	up	NN
cord-285180-32bxx94u	260	18	-	-	HYPH
cord-285180-32bxx94u	260	19	regulating	regulate	VBG
cord-285180-32bxx94u	260	20	HSC70	HSC70	NNP
cord-285180-32bxx94u	260	21	in	in	IN
cord-285180-32bxx94u	260	22	the	the	DT
cord-285180-32bxx94u	260	23	early	early	JJ
cord-285180-32bxx94u	260	24	phase	phase	NN
cord-285180-32bxx94u	260	25	of	of	IN
cord-285180-32bxx94u	260	26	the	the	DT
cord-285180-32bxx94u	260	27	infection	infection	NN
cord-285180-32bxx94u	260	28	,	,	,
cord-285180-32bxx94u	260	29	and	and	CC
cord-285180-32bxx94u	260	30	the	the	DT
cord-285180-32bxx94u	260	31	N	N	NNP
cord-285180-32bxx94u	260	32	protein	protein	NN
cord-285180-32bxx94u	260	33	seems	seem	VBZ
cord-285180-32bxx94u	260	34	to	to	TO
cord-285180-32bxx94u	260	35	be	be	VB
cord-285180-32bxx94u	260	36	involved	involve	VBN
cord-285180-32bxx94u	260	37	in	in	IN
cord-285180-32bxx94u	260	38	this	this	DT
cord-285180-32bxx94u	260	39	mechanism	mechanism	NN
cord-285180-32bxx94u	260	40	.	.	.
cord-285180-32bxx94u	261	1	In	in	IN
cord-285180-32bxx94u	261	2	addition	addition	NN
cord-285180-32bxx94u	261	3	,	,	,
cord-285180-32bxx94u	261	4	HSC70	HSC70	NNP
cord-285180-32bxx94u	261	5	mediates	mediate	VBZ
cord-285180-32bxx94u	261	6	the	the	DT
cord-285180-32bxx94u	261	7	nuclear	nuclear	JJ
cord-285180-32bxx94u	261	8	export	export	NN
cord-285180-32bxx94u	261	9	of	of	IN
cord-285180-32bxx94u	261	10	the	the	DT
cord-285180-32bxx94u	261	11	influenza	influenza	NN
cord-285180-32bxx94u	261	12	virus	virus	NN
cord-285180-32bxx94u	261	13	ribonucleoprotein	ribonucleoprotein	NN
cord-285180-32bxx94u	261	14	complex	complex	NN
cord-285180-32bxx94u	261	15	via	via	IN
cord-285180-32bxx94u	261	16	interaction	interaction	NN
cord-285180-32bxx94u	261	17	with	with	IN
cord-285180-32bxx94u	261	18	viral	viral	JJ
cord-285180-32bxx94u	261	19	proteins	protein	NNS
cord-285180-32bxx94u	261	20	M1	M1	NNP
cord-285180-32bxx94u	261	21	and	and	CC
cord-285180-32bxx94u	261	22	NS2	NS2	NNP
cord-285180-32bxx94u	261	23	(	(	-LRB-
cord-285180-32bxx94u	261	24	Watanabe	Watanabe	NNP
cord-285180-32bxx94u	261	25	et	et	NNP
cord-285180-32bxx94u	261	26	al	al	NNP
cord-285180-32bxx94u	261	27	.	.	NNP
cord-285180-32bxx94u	261	28	,	,	,
cord-285180-32bxx94u	261	29	2006	2006	CD
cord-285180-32bxx94u	261	30	(	(	-LRB-
cord-285180-32bxx94u	261	31	Watanabe	Watanabe	NNP
cord-285180-32bxx94u	261	32	et	et	NNP
cord-285180-32bxx94u	261	33	al	al	NNP
cord-285180-32bxx94u	261	34	.	.	NNP
cord-285180-32bxx94u	261	35	,	,	,
cord-285180-32bxx94u	261	36	,	,	,
cord-285180-32bxx94u	261	37	2014	2014	CD
cord-285180-32bxx94u	261	38	.	.	.
cord-285180-32bxx94u	262	1	In	in	IN
cord-285180-32bxx94u	262	2	the	the	DT
cord-285180-32bxx94u	262	3	present	present	JJ
cord-285180-32bxx94u	262	4	study	study	NN
cord-285180-32bxx94u	262	5	,	,	,
cord-285180-32bxx94u	262	6	we	-PRON-	PRP
cord-285180-32bxx94u	262	7	found	find	VBD
cord-285180-32bxx94u	262	8	that	that	IN
cord-285180-32bxx94u	262	9	PDCoV	pdcov	NN
cord-285180-32bxx94u	262	10	N	n	NN
cord-285180-32bxx94u	262	11	can	can	MD
cord-285180-32bxx94u	262	12	be	be	VB
cord-285180-32bxx94u	262	13	localized	localize	VBN
cord-285180-32bxx94u	262	14	to	to	IN
cord-285180-32bxx94u	262	15	the	the	DT
cord-285180-32bxx94u	262	16	nucleolus	nucleolus	NN
cord-285180-32bxx94u	262	17	in	in	IN
cord-285180-32bxx94u	262	18	Nexpressing	Nexpressing	NNP
cord-285180-32bxx94u	262	19	cells	cell	NNS
cord-285180-32bxx94u	262	20	.	.	.
cord-285180-32bxx94u	263	1	On	on	IN
cord-285180-32bxx94u	263	2	the	the	DT
cord-285180-32bxx94u	263	3	other	other	JJ
cord-285180-32bxx94u	263	4	hand	hand	NN
cord-285180-32bxx94u	263	5	,	,	,
cord-285180-32bxx94u	263	6	N	n	CD
cord-285180-32bxx94u	263	7	proteins	protein	NNS
cord-285180-32bxx94u	263	8	must	must	MD
cord-285180-32bxx94u	263	9	be	be	VB
cord-285180-32bxx94u	263	10	trafficked	traffic	VBN
cord-285180-32bxx94u	263	11	from	from	IN
cord-285180-32bxx94u	263	12	the	the	DT
cord-285180-32bxx94u	263	13	nucleolus	nucleolus	NN
cord-285180-32bxx94u	263	14	to	to	IN
cord-285180-32bxx94u	263	15	the	the	DT
cord-285180-32bxx94u	263	16	cytoplasm	cytoplasm	NN
cord-285180-32bxx94u	263	17	to	to	TO
cord-285180-32bxx94u	263	18	accomplish	accomplish	VB
cord-285180-32bxx94u	263	19	nucleocapsid	nucleocapsid	NNP
cord-285180-32bxx94u	263	20	assembly	assembly	NNP
cord-285180-32bxx94u	263	21	as	as	RB
cord-285180-32bxx94u	263	22	well	well	RB
cord-285180-32bxx94u	263	23	as	as	IN
cord-285180-32bxx94u	263	24	viral	viral	JJ
cord-285180-32bxx94u	263	25	RNA	RNA	NNP
cord-285180-32bxx94u	263	26	synthesis	synthesis	NN
cord-285180-32bxx94u	263	27	and	and	CC
cord-285180-32bxx94u	263	28	virus	virus	NN
cord-285180-32bxx94u	263	29	-	-	HYPH
cord-285180-32bxx94u	263	30	host	host	NN
cord-285180-32bxx94u	263	31	interactions	interaction	NNS
cord-285180-32bxx94u	263	32	.	.	.
cord-285180-32bxx94u	264	1	According	accord	VBG
cord-285180-32bxx94u	264	2	to	to	IN
cord-285180-32bxx94u	264	3	our	-PRON-	PRP$
cord-285180-32bxx94u	264	4	results	result	NNS
cord-285180-32bxx94u	264	5	and	and	CC
cord-285180-32bxx94u	264	6	existing	exist	VBG
cord-285180-32bxx94u	264	7	data	datum	NNS
cord-285180-32bxx94u	264	8	,	,	,
cord-285180-32bxx94u	264	9	HSC70	HSC70	NNP
cord-285180-32bxx94u	264	10	may	may	MD
cord-285180-32bxx94u	264	11	facilitate	facilitate	VB
cord-285180-32bxx94u	264	12	the	the	DT
cord-285180-32bxx94u	264	13	export	export	NN
cord-285180-32bxx94u	264	14	of	of	IN
cord-285180-32bxx94u	264	15	PDCoV	pdcov	NN
cord-285180-32bxx94u	264	16	N	n	CD
cord-285180-32bxx94u	264	17	from	from	IN
cord-285180-32bxx94u	264	18	the	the	DT
cord-285180-32bxx94u	264	19	nucleolus	nucleolus	NN
cord-285180-32bxx94u	264	20	to	to	TO
cord-285180-32bxx94u	264	21	complete	complete	VB
cord-285180-32bxx94u	264	22	the	the	DT
cord-285180-32bxx94u	264	23	viral	viral	JJ
cord-285180-32bxx94u	264	24	life	life	NN
cord-285180-32bxx94u	264	25	cycle	cycle	NN
cord-285180-32bxx94u	264	26	.	.	.
cord-285180-32bxx94u	265	1	Like	like	IN
cord-285180-32bxx94u	265	2	many	many	JJ
cord-285180-32bxx94u	265	3	other	other	JJ
cord-285180-32bxx94u	265	4	viruses	virus	NNS
cord-285180-32bxx94u	265	5	,	,	,
cord-285180-32bxx94u	265	6	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	265	7	turn	turn	VBP
cord-285180-32bxx94u	265	8	off	off	RP
cord-285180-32bxx94u	265	9	host	host	NN
cord-285180-32bxx94u	265	10	protein	protein	NN
cord-285180-32bxx94u	265	11	translation	translation	NN
cord-285180-32bxx94u	265	12	,	,	,
cord-285180-32bxx94u	265	13	while	while	IN
cord-285180-32bxx94u	265	14	continuing	continue	VBG
cord-285180-32bxx94u	265	15	to	to	IN
cord-285180-32bxx94u	265	16	the	the	DT
cord-285180-32bxx94u	265	17	synthesis	synthesis	NN
cord-285180-32bxx94u	265	18	of	of	IN
cord-285180-32bxx94u	265	19	their	-PRON-	PRP$
cord-285180-32bxx94u	265	20	own	own	JJ
cord-285180-32bxx94u	265	21	gene	gene	NN
cord-285180-32bxx94u	265	22	products	product	NNS
cord-285180-32bxx94u	265	23	to	to	TO
cord-285180-32bxx94u	265	24	finish	finish	VB
cord-285180-32bxx94u	265	25	viral	viral	JJ
cord-285180-32bxx94u	265	26	replication	replication	NN
cord-285180-32bxx94u	265	27	.	.	.
cord-285180-32bxx94u	266	1	One	one	CD
cord-285180-32bxx94u	266	2	of	of	IN
cord-285180-32bxx94u	266	3	the	the	DT
cord-285180-32bxx94u	266	4	mechanisms	mechanism	NNS
cord-285180-32bxx94u	266	5	behind	behind	IN
cord-285180-32bxx94u	266	6	this	this	DT
cord-285180-32bxx94u	266	7	translational	translational	JJ
cord-285180-32bxx94u	266	8	suppression	suppression	NN
cord-285180-32bxx94u	266	9	is	be	VBZ
cord-285180-32bxx94u	266	10	through	through	IN
cord-285180-32bxx94u	266	11	interaction	interaction	NN
cord-285180-32bxx94u	266	12	of	of	IN
cord-285180-32bxx94u	266	13	the	the	DT
cord-285180-32bxx94u	266	14	N	n	CD
cord-285180-32bxx94u	266	15	protein	protein	NN
cord-285180-32bxx94u	266	16	with	with	IN
cord-285180-32bxx94u	266	17	elongation	elongation	NN
cord-285180-32bxx94u	266	18	factor	factor	NN
cord-285180-32bxx94u	266	19	1	1	CD
cord-285180-32bxx94u	266	20	␣	␣	NNP
cord-285180-32bxx94u	266	21	(	(	-LRB-
cord-285180-32bxx94u	266	22	EF1	EF1	NNP
cord-285180-32bxx94u	266	23	␣	␣	NNP
cord-285180-32bxx94u	266	24	)	)	-RRB-
cord-285180-32bxx94u	266	25	,	,	,
cord-285180-32bxx94u	266	26	a	a	DT
cord-285180-32bxx94u	266	27	major	major	JJ
cord-285180-32bxx94u	266	28	translation	translation	NN
cord-285180-32bxx94u	266	29	factor	factor	NN
cord-285180-32bxx94u	266	30	in	in	IN
cord-285180-32bxx94u	266	31	mammalian	mammalian	JJ
cord-285180-32bxx94u	266	32	cells	cell	NNS
cord-285180-32bxx94u	266	33	.	.	.
cord-285180-32bxx94u	267	1	In	in	IN
cord-285180-32bxx94u	267	2	the	the	DT
cord-285180-32bxx94u	267	3	present	present	JJ
cord-285180-32bxx94u	267	4	study	study	NN
cord-285180-32bxx94u	267	5	,	,	,
cord-285180-32bxx94u	267	6	the	the	DT
cord-285180-32bxx94u	267	7	amount	amount	NN
cord-285180-32bxx94u	267	8	of	of	IN
cord-285180-32bxx94u	267	9	another	another	DT
cord-285180-32bxx94u	267	10	translational	translational	JJ
cord-285180-32bxx94u	267	11	factor	factor	NN
cord-285180-32bxx94u	267	12	,	,	,
cord-285180-32bxx94u	267	13	EF2	EF2	NNP
cord-285180-32bxx94u	267	14	,	,	,
cord-285180-32bxx94u	267	15	was	be	VBD
cord-285180-32bxx94u	267	16	affected	affect	VBN
cord-285180-32bxx94u	267	17	by	by	IN
cord-285180-32bxx94u	267	18	the	the	DT
cord-285180-32bxx94u	267	19	host	host	NN
cord-285180-32bxx94u	267	20	response	response	NN
cord-285180-32bxx94u	267	21	to	to	IN
cord-285180-32bxx94u	267	22	the	the	DT
cord-285180-32bxx94u	267	23	PDCoV	pdcov	NN
cord-285180-32bxx94u	267	24	N	n	CD
cord-285180-32bxx94u	267	25	protein	protein	NN
cord-285180-32bxx94u	267	26	.	.	.
cord-285180-32bxx94u	268	1	Although	although	IN
cord-285180-32bxx94u	268	2	we	-PRON-	PRP
cord-285180-32bxx94u	268	3	do	do	VBP
cord-285180-32bxx94u	268	4	not	not	RB
cord-285180-32bxx94u	268	5	know	know	VB
cord-285180-32bxx94u	268	6	whether	whether	IN
cord-285180-32bxx94u	268	7	the	the	DT
cord-285180-32bxx94u	268	8	increased	increase	VBN
cord-285180-32bxx94u	268	9	expression	expression	NN
cord-285180-32bxx94u	268	10	of	of	IN
cord-285180-32bxx94u	268	11	EF2	ef2	NN
cord-285180-32bxx94u	268	12	is	be	VBZ
cord-285180-32bxx94u	268	13	related	relate	VBN
cord-285180-32bxx94u	268	14	to	to	IN
cord-285180-32bxx94u	268	15	its	-PRON-	PRP$
cord-285180-32bxx94u	268	16	binding	binding	NN
cord-285180-32bxx94u	268	17	to	to	IN
cord-285180-32bxx94u	268	18	PDCoV	pdcov	NN
cord-285180-32bxx94u	268	19	N	n	CD
cord-285180-32bxx94u	268	20	,	,	,
cord-285180-32bxx94u	268	21	such	such	JJ
cord-285180-32bxx94u	268	22	differential	differential	JJ
cord-285180-32bxx94u	268	23	expression	expression	NN
cord-285180-32bxx94u	268	24	of	of	IN
cord-285180-32bxx94u	268	25	a	a	DT
cord-285180-32bxx94u	268	26	translation	translation	NN
cord-285180-32bxx94u	268	27	factor	factor	NN
cord-285180-32bxx94u	268	28	may	may	MD
cord-285180-32bxx94u	268	29	be	be	VB
cord-285180-32bxx94u	268	30	associated	associate	VBN
cord-285180-32bxx94u	268	31	with	with	IN
cord-285180-32bxx94u	268	32	regulation	regulation	NN
cord-285180-32bxx94u	268	33	of	of	IN
cord-285180-32bxx94u	268	34	both	both	DT
cord-285180-32bxx94u	268	35	host	host	NN
cord-285180-32bxx94u	268	36	and	and	CC
cord-285180-32bxx94u	268	37	viral	viral	JJ
cord-285180-32bxx94u	268	38	protein	protein	NN
cord-285180-32bxx94u	268	39	synthesis	synthesis	NN
cord-285180-32bxx94u	268	40	.	.	.
cord-285180-32bxx94u	269	1	We	-PRON-	PRP
cord-285180-32bxx94u	269	2	also	also	RB
cord-285180-32bxx94u	269	3	found	find	VBD
cord-285180-32bxx94u	269	4	that	that	DT
cord-285180-32bxx94u	269	5	expression	expression	NN
cord-285180-32bxx94u	269	6	of	of	IN
cord-285180-32bxx94u	269	7	the	the	DT
cord-285180-32bxx94u	269	8	cytoskeletal	cytoskeletal	JJ
cord-285180-32bxx94u	269	9	protein	protein	NN
cord-285180-32bxx94u	269	10	ezrin	ezrin	NNP
cord-285180-32bxx94u	269	11	is	be	VBZ
cord-285180-32bxx94u	269	12	significantly	significantly	RB
cord-285180-32bxx94u	269	13	enhanced	enhance	VBN
cord-285180-32bxx94u	269	14	by	by	IN
cord-285180-32bxx94u	269	15	the	the	DT
cord-285180-32bxx94u	269	16	N	N	NNP
cord-285180-32bxx94u	269	17	protein	protein	NN
cord-285180-32bxx94u	269	18	.	.	.
cord-285180-32bxx94u	270	1	Ezrin	Ezrin	NNP
cord-285180-32bxx94u	270	2	is	be	VBZ
cord-285180-32bxx94u	270	3	a	a	DT
cord-285180-32bxx94u	270	4	member	member	NN
cord-285180-32bxx94u	270	5	of	of	IN
cord-285180-32bxx94u	270	6	the	the	DT
cord-285180-32bxx94u	270	7	ezrin	ezrin	NNP
cord-285180-32bxx94u	270	8	-	-	HYPH
cord-285180-32bxx94u	270	9	moesin	moesin	NNP
cord-285180-32bxx94u	270	10	-	-	HYPH
cord-285180-32bxx94u	270	11	radixin	radixin	NNP
cord-285180-32bxx94u	270	12	(	(	-LRB-
cord-285180-32bxx94u	270	13	EMR	EMR	NNP
cord-285180-32bxx94u	270	14	)	)	-RRB-
cord-285180-32bxx94u	270	15	family	family	NN
cord-285180-32bxx94u	270	16	of	of	IN
cord-285180-32bxx94u	270	17	host	host	NN
cord-285180-32bxx94u	270	18	cytoskeletal	cytoskeletal	JJ
cord-285180-32bxx94u	270	19	proteins	protein	NNS
cord-285180-32bxx94u	270	20	that	that	WDT
cord-285180-32bxx94u	270	21	organize	organize	VBP
cord-285180-32bxx94u	270	22	the	the	DT
cord-285180-32bxx94u	270	23	cortical	cortical	JJ
cord-285180-32bxx94u	270	24	cytoskeleton	cytoskeleton	NN
cord-285180-32bxx94u	270	25	by	by	IN
cord-285180-32bxx94u	270	26	mediating	mediate	VBG
cord-285180-32bxx94u	270	27	interactions	interaction	NNS
cord-285180-32bxx94u	270	28	between	between	IN
cord-285180-32bxx94u	270	29	actin	actin	NN
cord-285180-32bxx94u	270	30	and	and	CC
cord-285180-32bxx94u	270	31	the	the	DT
cord-285180-32bxx94u	270	32	plasma	plasma	NN
cord-285180-32bxx94u	270	33	membrane	membrane	NN
cord-285180-32bxx94u	270	34	proteins	protein	NNS
cord-285180-32bxx94u	270	35	and	and	CC
cord-285180-32bxx94u	270	36	function	function	VBP
cord-285180-32bxx94u	270	37	as	as	IN
cord-285180-32bxx94u	270	38	signal	signal	NN
cord-285180-32bxx94u	270	39	transducers	transducer	NNS
cord-285180-32bxx94u	270	40	in	in	IN
cord-285180-32bxx94u	270	41	numerous	numerous	JJ
cord-285180-32bxx94u	270	42	signaling	signal	VBG
cord-285180-32bxx94u	270	43	pathways	pathway	NNS
cord-285180-32bxx94u	270	44	(	(	-LRB-
cord-285180-32bxx94u	270	45	Neisch	Neisch	NNP
cord-285180-32bxx94u	270	46	and	and	CC
cord-285180-32bxx94u	270	47	Fehon	Fehon	NNP
cord-285180-32bxx94u	270	48	,	,	,
cord-285180-32bxx94u	270	49	2011	2011	CD
cord-285180-32bxx94u	270	50	)	)	-RRB-
cord-285180-32bxx94u	270	51	.	.	.
cord-285180-32bxx94u	271	1	The	the	DT
cord-285180-32bxx94u	271	2	EMR	EMR	NNP
cord-285180-32bxx94u	271	3	also	also	RB
cord-285180-32bxx94u	271	4	modulate	modulate	VBP
cord-285180-32bxx94u	271	5	RNA	RNA	NNP
cord-285180-32bxx94u	271	6	virus	virus	NN
cord-285180-32bxx94u	271	7	infection	infection	NN
cord-285180-32bxx94u	271	8	by	by	IN
cord-285180-32bxx94u	271	9	regulating	regulate	VBG
cord-285180-32bxx94u	271	10	stable	stable	JJ
cord-285180-32bxx94u	271	11	and	and	CC
cord-285180-32bxx94u	271	12	dynamic	dynamic	JJ
cord-285180-32bxx94u	271	13	microtubule	microtubule	NN
cord-285180-32bxx94u	271	14	formation	formation	NN
cord-285180-32bxx94u	272	1	(	(	-LRB-
cord-285180-32bxx94u	272	2	Bukong	Bukong	NNP
cord-285180-32bxx94u	272	3	et	et	NNP
cord-285180-32bxx94u	272	4	al	al	NNP
cord-285180-32bxx94u	272	5	.	.	.
cord-285180-32bxx94u	273	1	,	,	,
cord-285180-32bxx94u	273	2	2013	2013	CD
cord-285180-32bxx94u	273	3	;	;	:
cord-285180-32bxx94u	273	4	Haedicke	Haedicke	NNP
cord-285180-32bxx94u	273	5	et	et	NNP
cord-285180-32bxx94u	273	6	al	al	NNP
cord-285180-32bxx94u	273	7	.	.	NNP
cord-285180-32bxx94u	273	8	,	,	,
cord-285180-32bxx94u	273	9	2008	2008	CD
cord-285180-32bxx94u	273	10	;	;	:
cord-285180-32bxx94u	273	11	Naghavi	Naghavi	NNP
cord-285180-32bxx94u	273	12	et	et	NNP
cord-285180-32bxx94u	273	13	al	al	NNP
cord-285180-32bxx94u	273	14	.	.	NNP
cord-285180-32bxx94u	273	15	,	,	,
cord-285180-32bxx94u	273	16	2007	2007	CD
cord-285180-32bxx94u	273	17	)	)	-RRB-
cord-285180-32bxx94u	273	18	.	.	.
cord-285180-32bxx94u	274	1	Given	give	VBN
cord-285180-32bxx94u	274	2	the	the	DT
cord-285180-32bxx94u	274	3	biological	biological	JJ
cord-285180-32bxx94u	274	4	features	feature	NNS
cord-285180-32bxx94u	274	5	of	of	IN
cord-285180-32bxx94u	274	6	the	the	DT
cord-285180-32bxx94u	274	7	EMR	EMR	NNP
cord-285180-32bxx94u	274	8	proteins	protein	NNS
cord-285180-32bxx94u	274	9	,	,	,
cord-285180-32bxx94u	274	10	the	the	DT
cord-285180-32bxx94u	274	11	up	up	JJ
cord-285180-32bxx94u	274	12	-	-	HYPH
cord-285180-32bxx94u	274	13	regulation	regulation	NN
cord-285180-32bxx94u	274	14	of	of	IN
cord-285180-32bxx94u	274	15	ezrin	ezrin	NNP
cord-285180-32bxx94u	274	16	in	in	IN
cord-285180-32bxx94u	274	17	our	-PRON-	PRP$
cord-285180-32bxx94u	274	18	study	study	NN
cord-285180-32bxx94u	274	19	suggests	suggest	VBZ
cord-285180-32bxx94u	274	20	that	that	IN
cord-285180-32bxx94u	274	21	the	the	DT
cord-285180-32bxx94u	274	22	PDCoV	pdcov	NN
cord-285180-32bxx94u	274	23	N	n	NN
cord-285180-32bxx94u	274	24	protein	protein	NN
cord-285180-32bxx94u	274	25	may	may	MD
cord-285180-32bxx94u	274	26	manipulate	manipulate	VB
cord-285180-32bxx94u	274	27	the	the	DT
cord-285180-32bxx94u	274	28	host	host	NN
cord-285180-32bxx94u	274	29	cytoskeletal	cytoskeletal	JJ
cord-285180-32bxx94u	274	30	network	network	NN
cord-285180-32bxx94u	274	31	and	and	CC
cord-285180-32bxx94u	274	32	cell	cell	NN
cord-285180-32bxx94u	274	33	signaling	signaling	NN
cord-285180-32bxx94u	274	34	,	,	,
cord-285180-32bxx94u	274	35	possibly	possibly	RB
cord-285180-32bxx94u	274	36	to	to	TO
cord-285180-32bxx94u	274	37	facilitate	facilitate	VB
cord-285180-32bxx94u	274	38	the	the	DT
cord-285180-32bxx94u	274	39	processes	process	NNS
cord-285180-32bxx94u	274	40	of	of	IN
cord-285180-32bxx94u	274	41	viral	viral	JJ
cord-285180-32bxx94u	274	42	infection	infection	NN
cord-285180-32bxx94u	274	43	and	and	CC
cord-285180-32bxx94u	274	44	replication	replication	NN
cord-285180-32bxx94u	274	45	.	.	.
cord-285180-32bxx94u	275	1	In	in	IN
cord-285180-32bxx94u	275	2	contrast	contrast	NN
cord-285180-32bxx94u	275	3	,	,	,
cord-285180-32bxx94u	275	4	the	the	DT
cord-285180-32bxx94u	275	5	expression	expression	NN
cord-285180-32bxx94u	275	6	of	of	IN
cord-285180-32bxx94u	275	7	translocon	translocon	NN
cord-285180-32bxx94u	275	8	-	-	HYPH
cord-285180-32bxx94u	275	9	associated	associate	VBN
cord-285180-32bxx94u	275	10	protein	protein	NN
cord-285180-32bxx94u	275	11	subunit	subunit	NN
cord-285180-32bxx94u	275	12	delta	delta	NN
cord-285180-32bxx94u	275	13	(	(	-LRB-
cord-285180-32bxx94u	275	14	TRAPD	TRAPD	NNP
cord-285180-32bxx94u	275	15	)	)	-RRB-
cord-285180-32bxx94u	275	16	is	be	VBZ
cord-285180-32bxx94u	275	17	suppressed	suppress	VBN
cord-285180-32bxx94u	275	18	in	in	IN
cord-285180-32bxx94u	275	19	cells	cell	NNS
cord-285180-32bxx94u	275	20	expressing	express	VBG
cord-285180-32bxx94u	275	21	the	the	DT
cord-285180-32bxx94u	275	22	PDCoV	pdcov	NN
cord-285180-32bxx94u	275	23	N	n	CD
cord-285180-32bxx94u	275	24	protein	protein	NN
cord-285180-32bxx94u	275	25	,	,	,
cord-285180-32bxx94u	275	26	according	accord	VBG
cord-285180-32bxx94u	275	27	to	to	IN
cord-285180-32bxx94u	275	28	our	-PRON-	PRP$
cord-285180-32bxx94u	275	29	results	result	NNS
cord-285180-32bxx94u	275	30	.	.	.
cord-285180-32bxx94u	276	1	TRAPD	TRAPD	NNP
cord-285180-32bxx94u	276	2	is	be	VBZ
cord-285180-32bxx94u	276	3	a	a	DT
cord-285180-32bxx94u	276	4	part	part	NN
cord-285180-32bxx94u	276	5	of	of	IN
cord-285180-32bxx94u	276	6	the	the	DT
cord-285180-32bxx94u	276	7	TRAP	trap	NN
cord-285180-32bxx94u	276	8	complex	complex	NN
cord-285180-32bxx94u	276	9	that	that	WDT
cord-285180-32bxx94u	276	10	is	be	VBZ
cord-285180-32bxx94u	276	11	involved	involve	VBN
cord-285180-32bxx94u	276	12	in	in	IN
cord-285180-32bxx94u	276	13	translocating	translocate	VBG
cord-285180-32bxx94u	276	14	proteins	protein	NNS
cord-285180-32bxx94u	276	15	across	across	IN
cord-285180-32bxx94u	276	16	the	the	DT
cord-285180-32bxx94u	276	17	ER	ER	NNP
cord-285180-32bxx94u	276	18	membrane	membrane	NN
cord-285180-32bxx94u	276	19	and	and	CC
cord-285180-32bxx94u	276	20	in	in	IN
cord-285180-32bxx94u	276	21	regulating	regulate	VBG
cord-285180-32bxx94u	276	22	the	the	DT
cord-285180-32bxx94u	276	23	retention	retention	NN
cord-285180-32bxx94u	276	24	of	of	IN
cord-285180-32bxx94u	276	25	ER	ER	NNP
cord-285180-32bxx94u	276	26	resident	resident	NN
cord-285180-32bxx94u	276	27	proteins	protein	NNS
cord-285180-32bxx94u	276	28	(	(	-LRB-
cord-285180-32bxx94u	276	29	Fons	Fons	NNP
cord-285180-32bxx94u	276	30	et	et	NNP
cord-285180-32bxx94u	276	31	al	al	NNP
cord-285180-32bxx94u	276	32	.	.	NNP
cord-285180-32bxx94u	276	33	,	,	,
cord-285180-32bxx94u	276	34	2003	2003	CD
cord-285180-32bxx94u	276	35	)	)	-RRB-
cord-285180-32bxx94u	276	36	.	.	.
cord-285180-32bxx94u	277	1	Coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	277	2	acquire	acquire	VBP
cord-285180-32bxx94u	277	3	their	-PRON-	PRP$
cord-285180-32bxx94u	277	4	lipid	lipid	NN
cord-285180-32bxx94u	277	5	envelop	envelop	NN
cord-285180-32bxx94u	277	6	via	via	IN
cord-285180-32bxx94u	277	7	budding	bud	VBG
cord-285180-32bxx94u	277	8	of	of	IN
cord-285180-32bxx94u	277	9	the	the	DT
cord-285180-32bxx94u	277	10	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	277	11	through	through	IN
cord-285180-32bxx94u	277	12	the	the	DT
cord-285180-32bxx94u	277	13	ER	ER	NNP
cord-285180-32bxx94u	277	14	-	-	HYPH
cord-285180-32bxx94u	277	15	Golgi	Golgi	NNP
cord-285180-32bxx94u	277	16	intermediate	intermediate	JJ
cord-285180-32bxx94u	277	17	compartment	compartment	NN
cord-285180-32bxx94u	277	18	(	(	-LRB-
cord-285180-32bxx94u	277	19	McBride	McBride	NNP
cord-285180-32bxx94u	277	20	et	et	NNP
cord-285180-32bxx94u	277	21	al	al	NNP
cord-285180-32bxx94u	277	22	.	.	NNP
cord-285180-32bxx94u	277	23	,	,	,
cord-285180-32bxx94u	277	24	2014	2014	CD
cord-285180-32bxx94u	277	25	)	)	-RRB-
cord-285180-32bxx94u	277	26	.	.	.
cord-285180-32bxx94u	278	1	The	the	DT
cord-285180-32bxx94u	278	2	down	down	JJ
cord-285180-32bxx94u	278	3	-	-	HYPH
cord-285180-32bxx94u	278	4	regulation	regulation	NN
cord-285180-32bxx94u	278	5	of	of	IN
cord-285180-32bxx94u	278	6	TRAPD	TRAPD	NNP
cord-285180-32bxx94u	278	7	may	may	MD
cord-285180-32bxx94u	278	8	lead	lead	VB
cord-285180-32bxx94u	278	9	to	to	IN
cord-285180-32bxx94u	278	10	the	the	DT
cord-285180-32bxx94u	278	11	release	release	NN
cord-285180-32bxx94u	278	12	of	of	IN
cord-285180-32bxx94u	278	13	cellular	cellular	JJ
cord-285180-32bxx94u	278	14	proteins	protein	NNS
cord-285180-32bxx94u	278	15	from	from	IN
cord-285180-32bxx94u	278	16	the	the	DT
cord-285180-32bxx94u	278	17	ER	ER	NNP
cord-285180-32bxx94u	278	18	during	during	IN
cord-285180-32bxx94u	278	19	PDCoV	pdcov	JJ
cord-285180-32bxx94u	278	20	replication	replication	NN
cord-285180-32bxx94u	278	21	,	,	,
cord-285180-32bxx94u	278	22	which	which	WDT
cord-285180-32bxx94u	278	23	in	in	IN
cord-285180-32bxx94u	278	24	turn	turn	NN
cord-285180-32bxx94u	278	25	,	,	,
cord-285180-32bxx94u	278	26	promotes	promote	VBZ
cord-285180-32bxx94u	278	27	translocation	translocation	NN
cord-285180-32bxx94u	278	28	of	of	IN
cord-285180-32bxx94u	278	29	envelope	envelope	NN
cord-285180-32bxx94u	278	30	-	-	HYPH
cord-285180-32bxx94u	278	31	associated	associate	VBN
cord-285180-32bxx94u	278	32	viral	viral	JJ
cord-285180-32bxx94u	278	33	structural	structural	JJ
cord-285180-32bxx94u	278	34	proteins	protein	NNS
cord-285180-32bxx94u	278	35	to	to	IN
cord-285180-32bxx94u	278	36	the	the	DT
cord-285180-32bxx94u	278	37	ER	ER	NNP
cord-285180-32bxx94u	278	38	membrane	membrane	NN
cord-285180-32bxx94u	278	39	-the	-the	ADD
cord-285180-32bxx94u	278	40	site	site	NN
cord-285180-32bxx94u	278	41	of	of	IN
cord-285180-32bxx94u	278	42	budding	bud	VBG
cord-285180-32bxx94u	278	43	-to	-to	ADD
cord-285180-32bxx94u	278	44	facilitate	facilitate	JJ
cord-285180-32bxx94u	278	45	virus	virus	NN
cord-285180-32bxx94u	278	46	assembly	assembly	NN
cord-285180-32bxx94u	278	47	.	.	.
cord-285180-32bxx94u	279	1	Eukaryotic	eukaryotic	JJ
cord-285180-32bxx94u	279	2	cells	cell	NNS
cord-285180-32bxx94u	279	3	reprogram	reprogram	VBP
cord-285180-32bxx94u	279	4	their	-PRON-	PRP$
cord-285180-32bxx94u	279	5	metabolism	metabolism	NN
cord-285180-32bxx94u	279	6	to	to	TO
cord-285180-32bxx94u	279	7	adapt	adapt	VB
cord-285180-32bxx94u	279	8	to	to	IN
cord-285180-32bxx94u	279	9	stress	stress	NN
cord-285180-32bxx94u	279	10	-	-	HYPH
cord-285180-32bxx94u	279	11	induced	induce	VBN
cord-285180-32bxx94u	279	12	damage	damage	NN
cord-285180-32bxx94u	279	13	in	in	IN
cord-285180-32bxx94u	279	14	response	response	NN
cord-285180-32bxx94u	279	15	to	to	IN
cord-285180-32bxx94u	279	16	environmental	environmental	JJ
cord-285180-32bxx94u	279	17	stressors	stressor	NNS
cord-285180-32bxx94u	279	18	.	.	.
cord-285180-32bxx94u	280	1	Among	among	IN
cord-285180-32bxx94u	280	2	our	-PRON-	PRP$
cord-285180-32bxx94u	280	3	differentially	differentially	RB
cord-285180-32bxx94u	280	4	expressed	express	VBN
cord-285180-32bxx94u	280	5	proteins	protein	NNS
cord-285180-32bxx94u	280	6	,	,	,
cord-285180-32bxx94u	280	7	some	some	DT
cord-285180-32bxx94u	280	8	are	be	VBP
cord-285180-32bxx94u	280	9	either	either	RB
cord-285180-32bxx94u	280	10	directly	directly	RB
cord-285180-32bxx94u	280	11	or	or	CC
cord-285180-32bxx94u	280	12	indirectly	indirectly	RB
cord-285180-32bxx94u	280	13	involved	involve	VBN
cord-285180-32bxx94u	280	14	in	in	IN
cord-285180-32bxx94u	280	15	metabolism	metabolism	NN
cord-285180-32bxx94u	280	16	.	.	.
cord-285180-32bxx94u	281	1	One	one	CD
cord-285180-32bxx94u	281	2	hypothesis	hypothesis	NN
cord-285180-32bxx94u	281	3	that	that	WDT
cord-285180-32bxx94u	281	4	can	can	MD
cord-285180-32bxx94u	281	5	explain	explain	VB
cord-285180-32bxx94u	281	6	this	this	DT
cord-285180-32bxx94u	281	7	result	result	NN
cord-285180-32bxx94u	281	8	is	be	VBZ
cord-285180-32bxx94u	281	9	that	that	IN
cord-285180-32bxx94u	281	10	production	production	NN
cord-285180-32bxx94u	281	11	of	of	IN
cord-285180-32bxx94u	281	12	the	the	DT
cord-285180-32bxx94u	281	13	N	N	NNP
cord-285180-32bxx94u	281	14	protein	protein	NN
cord-285180-32bxx94u	281	15	affects	affect	VBZ
cord-285180-32bxx94u	281	16	cellular	cellular	JJ
cord-285180-32bxx94u	281	17	biosynthesis	biosynthesis	NN
cord-285180-32bxx94u	281	18	by	by	IN
cord-285180-32bxx94u	281	19	modulating	modulate	VBG
cord-285180-32bxx94u	281	20	the	the	DT
cord-285180-32bxx94u	281	21	expression	expression	NN
cord-285180-32bxx94u	281	22	of	of	IN
cord-285180-32bxx94u	281	23	metabolism	metabolism	NN
cord-285180-32bxx94u	281	24	-	-	HYPH
cord-285180-32bxx94u	281	25	related	relate	VBN
cord-285180-32bxx94u	281	26	proteins	protein	NNS
cord-285180-32bxx94u	281	27	,	,	,
cord-285180-32bxx94u	281	28	which	which	WDT
cord-285180-32bxx94u	281	29	in	in	IN
cord-285180-32bxx94u	281	30	turn	turn	NN
cord-285180-32bxx94u	281	31	remodels	remodel	VBZ
cord-285180-32bxx94u	281	32	the	the	DT
cord-285180-32bxx94u	281	33	intracellular	intracellular	JJ
cord-285180-32bxx94u	281	34	environment	environment	NN
cord-285180-32bxx94u	281	35	for	for	IN
cord-285180-32bxx94u	281	36	optimal	optimal	JJ
cord-285180-32bxx94u	281	37	PDCoV	pdcov	NN
cord-285180-32bxx94u	281	38	replication	replication	NN
cord-285180-32bxx94u	281	39	.	.	.
cord-285180-32bxx94u	282	1	In	in	IN
cord-285180-32bxx94u	282	2	conclusion	conclusion	NN
cord-285180-32bxx94u	282	3	,	,	,
cord-285180-32bxx94u	282	4	to	to	IN
cord-285180-32bxx94u	282	5	our	-PRON-	PRP$
cord-285180-32bxx94u	282	6	knowledge	knowledge	NN
cord-285180-32bxx94u	282	7	,	,	,
cord-285180-32bxx94u	282	8	this	this	DT
cord-285180-32bxx94u	282	9	is	be	VBZ
cord-285180-32bxx94u	282	10	the	the	DT
cord-285180-32bxx94u	282	11	first	first	JJ
cord-285180-32bxx94u	282	12	report	report	NN
cord-285180-32bxx94u	282	13	of	of	IN
cord-285180-32bxx94u	282	14	a	a	DT
cord-285180-32bxx94u	282	15	proteomic	proteomic	JJ
cord-285180-32bxx94u	282	16	analysis	analysis	NN
cord-285180-32bxx94u	282	17	of	of	IN
cord-285180-32bxx94u	282	18	cellular	cellular	JJ
cord-285180-32bxx94u	282	19	responses	response	NNS
cord-285180-32bxx94u	282	20	to	to	IN
cord-285180-32bxx94u	282	21	the	the	DT
cord-285180-32bxx94u	282	22	PDCoV	pdcov	NN
cord-285180-32bxx94u	282	23	N	n	CD
cord-285180-32bxx94u	282	24	protein	protein	NN
cord-285180-32bxx94u	282	25	.	.	.
cord-285180-32bxx94u	283	1	Although	although	IN
cord-285180-32bxx94u	283	2	definite	definite	JJ
cord-285180-32bxx94u	283	3	functions	function	NNS
cord-285180-32bxx94u	283	4	of	of	IN
cord-285180-32bxx94u	283	5	the	the	DT
cord-285180-32bxx94u	283	6	proteins	protein	NNS
cord-285180-32bxx94u	283	7	that	that	WDT
cord-285180-32bxx94u	283	8	we	-PRON-	PRP
cord-285180-32bxx94u	283	9	identified	identify	VBD
cord-285180-32bxx94u	283	10	here	here	RB
cord-285180-32bxx94u	283	11	were	be	VBD
cord-285180-32bxx94u	283	12	not	not	RB
cord-285180-32bxx94u	283	13	determined	determine	VBN
cord-285180-32bxx94u	283	14	,	,	,
cord-285180-32bxx94u	283	15	it	-PRON-	PRP
cord-285180-32bxx94u	283	16	is	be	VBZ
cord-285180-32bxx94u	283	17	likely	likely	JJ
cord-285180-32bxx94u	283	18	that	that	IN
cord-285180-32bxx94u	283	19	alterations	alteration	NNS
cord-285180-32bxx94u	283	20	in	in	IN
cord-285180-32bxx94u	283	21	their	-PRON-	PRP$
cord-285180-32bxx94u	283	22	expression	expression	NN
cord-285180-32bxx94u	283	23	are	be	VBP
cord-285180-32bxx94u	283	24	involved	involve	VBN
cord-285180-32bxx94u	283	25	in	in	IN
cord-285180-32bxx94u	283	26	virus	virus	NN
cord-285180-32bxx94u	283	27	-	-	HYPH
cord-285180-32bxx94u	283	28	host	host	NN
cord-285180-32bxx94u	283	29	interactions	interaction	NNS
cord-285180-32bxx94u	283	30	.	.	.
cord-285180-32bxx94u	284	1	To	to	TO
cord-285180-32bxx94u	284	2	resolve	resolve	VB
cord-285180-32bxx94u	284	3	these	these	DT
cord-285180-32bxx94u	284	4	questions	question	NNS
cord-285180-32bxx94u	284	5	as	as	RB
cord-285180-32bxx94u	284	6	well	well	RB
cord-285180-32bxx94u	284	7	as	as	IN
cord-285180-32bxx94u	284	8	performing	perform	VBG
cord-285180-32bxx94u	284	9	various	various	JJ
cord-285180-32bxx94u	284	10	PDCoV	pdcov	NN
cord-285180-32bxx94u	284	11	research	research	NN
cord-285180-32bxx94u	284	12	,	,	,
cord-285180-32bxx94u	284	13	obtaining	obtain	VBG
cord-285180-32bxx94u	284	14	a	a	DT
cord-285180-32bxx94u	284	15	Korean	korean	JJ
cord-285180-32bxx94u	284	16	PDCoV	pdcov	NN
cord-285180-32bxx94u	284	17	isolate	isolate	NN
cord-285180-32bxx94u	284	18	that	that	WDT
cord-285180-32bxx94u	284	19	can	can	MD
cord-285180-32bxx94u	284	20	grow	grow	VB
cord-285180-32bxx94u	284	21	in	in	IN
cord-285180-32bxx94u	284	22	cell	cell	NN
cord-285180-32bxx94u	284	23	culture	culture	NN
cord-285180-32bxx94u	284	24	is	be	VBZ
cord-285180-32bxx94u	284	25	necessary	necessary	JJ
cord-285180-32bxx94u	284	26	;	;	:
cord-285180-32bxx94u	284	27	we	-PRON-	PRP
cord-285180-32bxx94u	284	28	are	be	VBP
cord-285180-32bxx94u	284	29	currently	currently	RB
cord-285180-32bxx94u	284	30	working	work	VBG
cord-285180-32bxx94u	284	31	on	on	IN
cord-285180-32bxx94u	284	32	this	this	DT
cord-285180-32bxx94u	284	33	task	task	NN
cord-285180-32bxx94u	284	34	.	.	.
cord-285180-32bxx94u	285	1	In	in	IN
cord-285180-32bxx94u	285	2	future	future	JJ
cord-285180-32bxx94u	285	3	studies	study	NNS
cord-285180-32bxx94u	285	4	,	,	,
cord-285180-32bxx94u	285	5	we	-PRON-	PRP
cord-285180-32bxx94u	285	6	are	be	VBP
cord-285180-32bxx94u	285	7	planning	plan	VBG
cord-285180-32bxx94u	285	8	to	to	TO
cord-285180-32bxx94u	285	9	assess	assess	VB
cord-285180-32bxx94u	285	10	cellular	cellular	JJ
cord-285180-32bxx94u	285	11	responses	response	NNS
cord-285180-32bxx94u	285	12	to	to	IN
cord-285180-32bxx94u	285	13	PDCoV	pdcov	NN
cord-285180-32bxx94u	285	14	by	by	IN
cord-285180-32bxx94u	285	15	proteomic	proteomic	JJ
cord-285180-32bxx94u	285	16	analysis	analysis	NN
cord-285180-32bxx94u	285	17	to	to	TO
cord-285180-32bxx94u	285	18	validate	validate	VB
cord-285180-32bxx94u	285	19	our	-PRON-	PRP$
cord-285180-32bxx94u	285	20	present	present	JJ
cord-285180-32bxx94u	285	21	data	datum	NNS
cord-285180-32bxx94u	285	22	;	;	:
cord-285180-32bxx94u	285	23	the	the	DT
cord-285180-32bxx94u	285	24	proteins	protein	NNS
cord-285180-32bxx94u	285	25	that	that	WDT
cord-285180-32bxx94u	285	26	are	be	VBP
cord-285180-32bxx94u	285	27	differentially	differentially	RB
cord-285180-32bxx94u	285	28	expressed	express	VBN
cord-285180-32bxx94u	285	29	in	in	IN
cord-285180-32bxx94u	285	30	the	the	DT
cord-285180-32bxx94u	285	31	cells	cell	NNS
cord-285180-32bxx94u	285	32	overexpressing	overexpresse	VBG
cord-285180-32bxx94u	285	33	PDCoV	pdcov	NN
cord-285180-32bxx94u	285	34	N	n	CD
cord-285180-32bxx94u	285	35	or	or	CC
cord-285180-32bxx94u	285	36	in	in	IN
cord-285180-32bxx94u	285	37	the	the	DT
cord-285180-32bxx94u	285	38	cells	cell	NNS
cord-285180-32bxx94u	285	39	infected	infect	VBN
cord-285180-32bxx94u	285	40	with	with	IN
cord-285180-32bxx94u	285	41	PDCoV	pdcov	NN
cord-285180-32bxx94u	285	42	can	can	MD
cord-285180-32bxx94u	285	43	be	be	VB
cord-285180-32bxx94u	285	44	analyzed	analyze	VBN
cord-285180-32bxx94u	285	45	in	in	IN
cord-285180-32bxx94u	285	46	detail	detail	NN
cord-285180-32bxx94u	285	47	in	in	IN
cord-285180-32bxx94u	285	48	order	order	NN
cord-285180-32bxx94u	285	49	to	to	TO
cord-285180-32bxx94u	285	50	identify	identify	VB
cord-285180-32bxx94u	285	51	their	-PRON-	PRP$
cord-285180-32bxx94u	285	52	precise	precise	JJ
cord-285180-32bxx94u	285	53	function	function	NN
cord-285180-32bxx94u	285	54	in	in	IN
cord-285180-32bxx94u	285	55	the	the	DT
cord-285180-32bxx94u	285	56	replication	replication	NN
cord-285180-32bxx94u	285	57	of	of	IN
cord-285180-32bxx94u	285	58	PDCoV.	pdcov.	NN
cord-285180-32bxx94u	286	1	On	on	IN
cord-285180-32bxx94u	286	2	the	the	DT
cord-285180-32bxx94u	286	3	other	other	JJ
cord-285180-32bxx94u	286	4	hand	hand	NN
cord-285180-32bxx94u	286	5	,	,	,
cord-285180-32bxx94u	286	6	one	one	CD
cord-285180-32bxx94u	286	7	limitation	limitation	NN
cord-285180-32bxx94u	286	8	of	of	IN
cord-285180-32bxx94u	286	9	the	the	DT
cord-285180-32bxx94u	286	10	proteomic	proteomic	JJ
cord-285180-32bxx94u	286	11	methodology	methodology	NN
cord-285180-32bxx94u	286	12	used	use	VBN
cord-285180-32bxx94u	286	13	in	in	IN
cord-285180-32bxx94u	286	14	this	this	DT
cord-285180-32bxx94u	286	15	study	study	NN
cord-285180-32bxx94u	286	16	is	be	VBZ
cord-285180-32bxx94u	286	17	the	the	DT
cord-285180-32bxx94u	286	18	inability	inability	NN
cord-285180-32bxx94u	286	19	to	to	TO
cord-285180-32bxx94u	286	20	reliably	reliably	RB
cord-285180-32bxx94u	286	21	detect	detect	VB
cord-285180-32bxx94u	286	22	low	low	JJ
cord-285180-32bxx94u	286	23	-	-	HYPH
cord-285180-32bxx94u	286	24	molecular	molecular	JJ
cord-285180-32bxx94u	286	25	-	-	HYPH
cord-285180-32bxx94u	286	26	weight	weight	NN
cord-285180-32bxx94u	286	27	or	or	CC
cord-285180-32bxx94u	286	28	low	low	JJ
cord-285180-32bxx94u	286	29	-	-	HYPH
cord-285180-32bxx94u	286	30	abundance	abundance	NN
cord-285180-32bxx94u	286	31	proteins	protein	NNS
cord-285180-32bxx94u	286	32	such	such	JJ
cord-285180-32bxx94u	286	33	as	as	IN
cord-285180-32bxx94u	286	34	cytokines	cytokine	NNS
cord-285180-32bxx94u	286	35	,	,	,
cord-285180-32bxx94u	286	36	which	which	WDT
cord-285180-32bxx94u	286	37	are	be	VBP
cord-285180-32bxx94u	286	38	involved	involve	VBN
cord-285180-32bxx94u	286	39	in	in	IN
cord-285180-32bxx94u	286	40	the	the	DT
cord-285180-32bxx94u	286	41	host	host	NN
cord-285180-32bxx94u	286	42	immune	immune	JJ
cord-285180-32bxx94u	286	43	response	response	NN
cord-285180-32bxx94u	286	44	.	.	.
cord-285180-32bxx94u	287	1	Therefore	therefore	RB
cord-285180-32bxx94u	287	2	,	,	,
cord-285180-32bxx94u	287	3	more	more	RBR
cord-285180-32bxx94u	287	4	comprehensive	comprehensive	JJ
cord-285180-32bxx94u	287	5	works	work	NNS
cord-285180-32bxx94u	287	6	are	be	VBP
cord-285180-32bxx94u	287	7	also	also	RB
cord-285180-32bxx94u	287	8	needed	need	VBN
cord-285180-32bxx94u	287	9	to	to	TO
cord-285180-32bxx94u	287	10	expand	expand	VB
cord-285180-32bxx94u	287	11	our	-PRON-	PRP$
cord-285180-32bxx94u	287	12	present	present	JJ
cord-285180-32bxx94u	287	13	findings	finding	NNS
cord-285180-32bxx94u	287	14	and	and	CC
cord-285180-32bxx94u	287	15	to	to	TO
cord-285180-32bxx94u	287	16	explore	explore	VB
cord-285180-32bxx94u	287	17	other	other	JJ
cord-285180-32bxx94u	287	18	proteins	protein	NNS
cord-285180-32bxx94u	287	19	that	that	WDT
cord-285180-32bxx94u	287	20	may	may	MD
cord-285180-32bxx94u	287	21	play	play	VB
cord-285180-32bxx94u	287	22	a	a	DT
cord-285180-32bxx94u	287	23	role	role	NN
cord-285180-32bxx94u	287	24	in	in	IN
cord-285180-32bxx94u	287	25	host	host	NN
cord-285180-32bxx94u	287	26	responses	response	NNS
cord-285180-32bxx94u	287	27	to	to	IN
cord-285180-32bxx94u	287	28	this	this	DT
cord-285180-32bxx94u	287	29	protein	protein	NN
cord-285180-32bxx94u	287	30	.	.	.
cord-285180-32bxx94u	288	1	Nevertheless	nevertheless	RB
cord-285180-32bxx94u	288	2	,	,	,
cord-285180-32bxx94u	288	3	the	the	DT
cord-285180-32bxx94u	288	4	data	datum	NNS
cord-285180-32bxx94u	288	5	presented	present	VBN
cord-285180-32bxx94u	288	6	here	here	RB
cord-285180-32bxx94u	288	7	are	be	VBP
cord-285180-32bxx94u	288	8	expected	expect	VBN
cord-285180-32bxx94u	288	9	to	to	TO
cord-285180-32bxx94u	288	10	advance	advance	VB
cord-285180-32bxx94u	288	11	the	the	DT
cord-285180-32bxx94u	288	12	knowledge	knowledge	NN
cord-285180-32bxx94u	288	13	about	about	IN
cord-285180-32bxx94u	288	14	the	the	DT
cord-285180-32bxx94u	288	15	molecular	molecular	JJ
cord-285180-32bxx94u	288	16	mechanisms	mechanism	NNS
cord-285180-32bxx94u	288	17	associated	associate	VBN
cord-285180-32bxx94u	288	18	with	with	IN
cord-285180-32bxx94u	288	19	PDCoV	pdcov	NN
cord-285180-32bxx94u	288	20	-	-	HYPH
cord-285180-32bxx94u	288	21	host	host	NN
cord-285180-32bxx94u	288	22	interactions	interaction	NNS
cord-285180-32bxx94u	288	23	and	and	CC
cord-285180-32bxx94u	288	24	viral	viral	JJ
cord-285180-32bxx94u	288	25	pathogenesis	pathogenesis	NN
cord-285180-32bxx94u	288	26	.	.	.
cord-285180-32bxx94u	289	1	Identification	identification	NN
cord-285180-32bxx94u	289	2	of	of	IN
cord-285180-32bxx94u	289	3	cellular	cellular	JJ
cord-285180-32bxx94u	289	4	proteins	protein	NNS
cord-285180-32bxx94u	289	5	modified	modify	VBN
cord-285180-32bxx94u	289	6	in	in	IN
cord-285180-32bxx94u	289	7	response	response	NN
cord-285180-32bxx94u	289	8	to	to	IN
cord-285180-32bxx94u	289	9	African	african	JJ
cord-285180-32bxx94u	289	10	swine	swine	NN
cord-285180-32bxx94u	289	11	fever	fever	NN
cord-285180-32bxx94u	289	12	virus	virus	NN
cord-285180-32bxx94u	289	13	infection	infection	NN
cord-285180-32bxx94u	289	14	by	by	IN
cord-285180-32bxx94u	289	15	proteomics	proteomic	NNS
cord-285180-32bxx94u	289	16	A	a	DT
cord-285180-32bxx94u	289	17	rapid	rapid	JJ
cord-285180-32bxx94u	289	18	and	and	CC
cord-285180-32bxx94u	289	19	sensitive	sensitive	JJ
cord-285180-32bxx94u	289	20	method	method	NN
cord-285180-32bxx94u	289	21	for	for	IN
cord-285180-32bxx94u	289	22	the	the	DT
cord-285180-32bxx94u	289	23	quantitation	quantitation	NN
cord-285180-32bxx94u	289	24	of	of	IN
cord-285180-32bxx94u	289	25	microgram	microgram	NN
cord-285180-32bxx94u	289	26	quantities	quantity	NNS
cord-285180-32bxx94u	289	27	of	of	IN
cord-285180-32bxx94u	289	28	protein	protein	NN
cord-285180-32bxx94u	289	29	utilizing	utilize	VBG
cord-285180-32bxx94u	289	30	the	the	DT
cord-285180-32bxx94u	289	31	principle	principle	NN
cord-285180-32bxx94u	289	32	of	of	IN
cord-285180-32bxx94u	289	33	protein	protein	NN
cord-285180-32bxx94u	289	34	-	-	HYPH
cord-285180-32bxx94u	289	35	dye	dye	NN
cord-285180-32bxx94u	289	36	binding	bind	VBG
cord-285180-32bxx94u	289	37	Nuclear	nuclear	JJ
cord-285180-32bxx94u	289	38	heat	heat	NN
cord-285180-32bxx94u	289	39	shock	shock	NN
cord-285180-32bxx94u	289	40	response	response	NN
cord-285180-32bxx94u	289	41	and	and	CC
cord-285180-32bxx94u	289	42	novel	novel	JJ
cord-285180-32bxx94u	289	43	nuclear	nuclear	JJ
cord-285180-32bxx94u	289	44	domain	domain	NN
cord-285180-32bxx94u	289	45	10	10	CD
cord-285180-32bxx94u	289	46	reorganization	reorganization	NN
cord-285180-32bxx94u	289	47	in	in	IN
cord-285180-32bxx94u	289	48	respiratory	respiratory	JJ
cord-285180-32bxx94u	289	49	syncytial	syncytial	JJ
cord-285180-32bxx94u	289	50	virus	virus	NN
cord-285180-32bxx94u	289	51	-	-	HYPH
cord-285180-32bxx94u	289	52	infected	infect	VBN
cord-285180-32bxx94u	289	53	a549	a549	JJ
cord-285180-32bxx94u	289	54	cells	cell	NNS
cord-285180-32bxx94u	289	55	identified	identify	VBN
cord-285180-32bxx94u	289	56	by	by	IN
cord-285180-32bxx94u	289	57	high	high	JJ
cord-285180-32bxx94u	289	58	-	-	HYPH
cord-285180-32bxx94u	289	59	resolution	resolution	NN
cord-285180-32bxx94u	289	60	two	two	CD
cord-285180-32bxx94u	289	61	-	-	HYPH
cord-285180-32bxx94u	289	62	dimensional	dimensional	JJ
cord-285180-32bxx94u	289	63	gel	gel	NN
cord-285180-32bxx94u	289	64	electrophoresis	electrophoresis	NN
cord-285180-32bxx94u	289	65	Human	Human	NNP
cord-285180-32bxx94u	289	66	ezrin	ezrin	NNP
cord-285180-32bxx94u	289	67	-	-	HYPH
cord-285180-32bxx94u	289	68	moesin	moesin	NNP
cord-285180-32bxx94u	289	69	-	-	HYPH
cord-285180-32bxx94u	289	70	radixin	radixin	NN
cord-285180-32bxx94u	289	71	proteins	protein	NNS
cord-285180-32bxx94u	289	72	modulate	modulate	VBP
cord-285180-32bxx94u	289	73	hepatitis	hepatitis	NN
cord-285180-32bxx94u	289	74	C	c	NN
cord-285180-32bxx94u	289	75	virus	virus	NN
cord-285180-32bxx94u	289	76	infection	infection	NN
cord-285180-32bxx94u	289	77	Interaction	Interaction	NNP
cord-285180-32bxx94u	289	78	of	of	IN
cord-285180-32bxx94u	289	79	the	the	DT
cord-285180-32bxx94u	289	80	coronavirus	coronavirus	NN
cord-285180-32bxx94u	289	81	nucleoprotein	nucleoprotein	NNP
cord-285180-32bxx94u	289	82	with	with	IN
cord-285180-32bxx94u	289	83	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	289	84	antigens	antigen	NNS
cord-285180-32bxx94u	289	85	and	and	CC
cord-285180-32bxx94u	289	86	the	the	DT
cord-285180-32bxx94u	289	87	host	host	NN
cord-285180-32bxx94u	289	88	cell	cell	NN
cord-285180-32bxx94u	289	89	Heat	Heat	NNP
cord-285180-32bxx94u	289	90	shock	shock	NN
cord-285180-32bxx94u	289	91	cognate	cognate	JJ
cord-285180-32bxx94u	289	92	protein	protein	NN
cord-285180-32bxx94u	289	93	70	70	CD
cord-285180-32bxx94u	289	94	isoform	isoform	NN
cord-285180-32bxx94u	289	95	D	d	NN
cord-285180-32bxx94u	289	96	is	be	VBZ
cord-285180-32bxx94u	289	97	required	require	VBN
cord-285180-32bxx94u	289	98	for	for	IN
cord-285180-32bxx94u	289	99	clathrin	clathrin	NN
cord-285180-32bxx94u	289	100	-	-	HYPH
cord-285180-32bxx94u	289	101	dependent	dependent	JJ
cord-285180-32bxx94u	289	102	endocytosis	endocytosis	NN
cord-285180-32bxx94u	289	103	of	of	IN
cord-285180-32bxx94u	289	104	Japanese	japanese	JJ
cord-285180-32bxx94u	289	105	encephalitis	encephalitis	RB
cord-285180-32bxx94u	289	106	virus	virus	NN
cord-285180-32bxx94u	289	107	in	in	IN
cord-285180-32bxx94u	289	108	C6/36	C6/36	NNP
cord-285180-32bxx94u	289	109	cells	cell	NNS
cord-285180-32bxx94u	289	110	Virus	Virus	NNP
cord-285180-32bxx94u	289	111	Taxonomy	Taxonomy	NNP
cord-285180-32bxx94u	289	112	:	:	:
cord-285180-32bxx94u	290	1	Ninth	Ninth	NNP
cord-285180-32bxx94u	290	2	Report	Report	NNP
cord-285180-32bxx94u	290	3	of	of	IN
cord-285180-32bxx94u	290	4	the	the	DT
cord-285180-32bxx94u	290	5	International	International	NNP
cord-285180-32bxx94u	290	6	Committee	Committee	NNP
cord-285180-32bxx94u	290	7	on	on	IN
cord-285180-32bxx94u	290	8	Taxonomy	Taxonomy	NNP
cord-285180-32bxx94u	290	9	of	of	IN
cord-285180-32bxx94u	290	10	Viruses	Viruses	NNPS
cord-285180-32bxx94u	290	11	Apoptosis	Apoptosis	NNP
cord-285180-32bxx94u	290	12	:	:	:
cord-285180-32bxx94u	290	13	an	an	DT
cord-285180-32bxx94u	290	14	innate	innate	JJ
cord-285180-32bxx94u	290	15	immune	immune	JJ
cord-285180-32bxx94u	290	16	response	response	NN
cord-285180-32bxx94u	290	17	to	to	IN
cord-285180-32bxx94u	290	18	virus	virus	NN
cord-285180-32bxx94u	290	19	infection	infection	NN
cord-285180-32bxx94u	290	20	Routine	routine	JJ
cord-285180-32bxx94u	290	21	identification	identification	NN
cord-285180-32bxx94u	290	22	of	of	IN
cord-285180-32bxx94u	290	23	proteins	protein	NNS
cord-285180-32bxx94u	290	24	from	from	IN
cord-285180-32bxx94u	290	25	sodium	sodium	NN
cord-285180-32bxx94u	290	26	dodecyl	dodecyl	NNP
cord-285180-32bxx94u	290	27	sulfate	sulfate	NN
cord-285180-32bxx94u	290	28	-	-	HYPH
cord-285180-32bxx94u	290	29	polyacrylamide	polyacrylamide	NN
cord-285180-32bxx94u	290	30	gel	gel	NN
cord-285180-32bxx94u	290	31	electrophoresis	electrophoresis	NN
cord-285180-32bxx94u	290	32	(	(	-LRB-
cord-285180-32bxx94u	290	33	SDS	SDS	NNP
cord-285180-32bxx94u	290	34	-	-	HYPH
cord-285180-32bxx94u	290	35	PAGE	PAGE	NNP
cord-285180-32bxx94u	290	36	)	)	-RRB-
cord-285180-32bxx94u	290	37	gels	gel	NNS
cord-285180-32bxx94u	290	38	or	or	CC
cord-285180-32bxx94u	290	39	polyvinyl	polyvinyl	NN
cord-285180-32bxx94u	290	40	difluoride	difluoride	NN
cord-285180-32bxx94u	290	41	membranes	membrane	NNS
cord-285180-32bxx94u	290	42	using	use	VBG
cord-285180-32bxx94u	290	43	matrix	matrix	NN
cord-285180-32bxx94u	290	44	assisted	assist	VBN
cord-285180-32bxx94u	290	45	laser	laser	NN
cord-285180-32bxx94u	290	46	desorption	desorption	NN
cord-285180-32bxx94u	290	47	/	/	SYM
cord-285180-32bxx94u	290	48	ionization	ionization	NN
cord-285180-32bxx94u	290	49	-	-	HYPH
cord-285180-32bxx94u	290	50	time	time	NN
cord-285180-32bxx94u	290	51	of	of	IN
cord-285180-32bxx94u	290	52	flight	flight	NN
cord-285180-32bxx94u	290	53	-	-	HYPH
cord-285180-32bxx94u	290	54	mass	mass	NN
cord-285180-32bxx94u	290	55	spectrometry	spectrometry	NN
cord-285180-32bxx94u	290	56	(	(	-LRB-
cord-285180-32bxx94u	290	57	MALDI	MALDI	NNP
cord-285180-32bxx94u	290	58	-	-	HYPH
cord-285180-32bxx94u	290	59	TOF	TOF	NNP
cord-285180-32bxx94u	290	60	-	-	HYPH
cord-285180-32bxx94u	290	61	MS	MS	NNP
cord-285180-32bxx94u	290	62	)	)	-RRB-
cord-285180-32bxx94u	290	63	Substrate	substrate	NN
cord-285180-32bxx94u	290	64	-	-	HYPH
cord-285180-32bxx94u	290	65	specific	specific	JJ
cord-285180-32bxx94u	290	66	function	function	NN
cord-285180-32bxx94u	290	67	of	of	IN
cord-285180-32bxx94u	290	68	the	the	DT
cord-285180-32bxx94u	290	69	translocon	translocon	NNP
cord-285180-32bxx94u	290	70	-	-	HYPH
cord-285180-32bxx94u	290	71	associated	associate	VBN
cord-285180-32bxx94u	290	72	protein	protein	NN
cord-285180-32bxx94u	290	73	complex	complex	NN
cord-285180-32bxx94u	290	74	during	during	IN
cord-285180-32bxx94u	290	75	translocation	translocation	NN
cord-285180-32bxx94u	290	76	across	across	IN
cord-285180-32bxx94u	290	77	the	the	DT
cord-285180-32bxx94u	290	78	ER	ER	NNP
cord-285180-32bxx94u	290	79	membrane	membrane	NN
cord-285180-32bxx94u	290	80	Coronavirus	Coronavirus	NNP
cord-285180-32bxx94u	290	81	-	-	HYPH
cord-285180-32bxx94u	290	82	induced	induce	VBN
cord-285180-32bxx94u	290	83	ER	ER	NNP
cord-285180-32bxx94u	290	84	stress	stress	NN
cord-285180-32bxx94u	290	85	response	response	NN
cord-285180-32bxx94u	290	86	and	and	CC
cord-285180-32bxx94u	290	87	its	-PRON-	PRP$
cord-285180-32bxx94u	290	88	involvement	involvement	NN
cord-285180-32bxx94u	290	89	in	in	IN
cord-285180-32bxx94u	290	90	regulation	regulation	NN
cord-285180-32bxx94u	290	91	of	of	IN
cord-285180-32bxx94u	290	92	coronavirus	coronavirus	NN
cord-285180-32bxx94u	290	93	-	-	HYPH
cord-285180-32bxx94u	290	94	host	host	NN
cord-285180-32bxx94u	290	95	interactions	interaction	NNS
cord-285180-32bxx94u	290	96	Coronavirus	Coronavirus	NNP
cord-285180-32bxx94u	290	97	infection	infection	NN
cord-285180-32bxx94u	290	98	,	,	,
cord-285180-32bxx94u	290	99	ER	ER	NNP
cord-285180-32bxx94u	290	100	stress	stress	NN
cord-285180-32bxx94u	290	101	,	,	,
cord-285180-32bxx94u	290	102	apoptosis	apoptosis	NN
cord-285180-32bxx94u	290	103	and	and	CC
cord-285180-32bxx94u	290	104	innate	innate	JJ
cord-285180-32bxx94u	290	105	immunity	immunity	NN
cord-285180-32bxx94u	291	1	Different	different	JJ
cord-285180-32bxx94u	291	2	rotavirus	rotavirus	NN
cord-285180-32bxx94u	291	3	strains	strain	NNS
cord-285180-32bxx94u	291	4	enter	enter	VBP
cord-285180-32bxx94u	291	5	MA104	ma104	NN
cord-285180-32bxx94u	291	6	cells	cell	NNS
cord-285180-32bxx94u	291	7	through	through	IN
cord-285180-32bxx94u	291	8	different	different	JJ
cord-285180-32bxx94u	291	9	endocytic	endocytic	JJ
cord-285180-32bxx94u	291	10	pathways	pathway	NNS
cord-285180-32bxx94u	291	11	:	:	:
cord-285180-32bxx94u	291	12	the	the	DT
cord-285180-32bxx94u	291	13	role	role	NN
cord-285180-32bxx94u	291	14	of	of	IN
cord-285180-32bxx94u	291	15	clathrin	clathrin	NN
cord-285180-32bxx94u	291	16	-	-	HYPH
cord-285180-32bxx94u	291	17	mediated	mediate	VBN
cord-285180-32bxx94u	291	18	endocytosis	endocytosis	NN
cord-285180-32bxx94u	291	19	Correlation	correlation	NN
cord-285180-32bxx94u	291	20	between	between	IN
cord-285180-32bxx94u	291	21	protein	protein	NN
cord-285180-32bxx94u	291	22	and	and	CC
cord-285180-32bxx94u	291	23	mRNA	mrna	NN
cord-285180-32bxx94u	291	24	abundance	abundance	NN
cord-285180-32bxx94u	291	25	in	in	IN
cord-285180-32bxx94u	291	26	yeast	yeast	NN
cord-285180-32bxx94u	292	1	The	the	DT
cord-285180-32bxx94u	292	2	ezrin	ezrin	NNP
cord-285180-32bxx94u	292	3	-	-	HYPH
cord-285180-32bxx94u	292	4	radixin	radixin	NNP
cord-285180-32bxx94u	292	5	-	-	HYPH
cord-285180-32bxx94u	292	6	moesin	moesin	NNP
cord-285180-32bxx94u	292	7	family	family	NN
cord-285180-32bxx94u	292	8	member	member	NN
cord-285180-32bxx94u	292	9	ezrin	ezrin	NNP
cord-285180-32bxx94u	292	10	regulates	regulate	VBZ
cord-285180-32bxx94u	292	11	stable	stable	JJ
cord-285180-32bxx94u	292	12	microtubule	microtubule	JJ
cord-285180-32bxx94u	292	13	formation	formation	NN
cord-285180-32bxx94u	292	14	and	and	CC
cord-285180-32bxx94u	292	15	retroviral	retroviral	JJ
cord-285180-32bxx94u	292	16	infection	infection	NN
cord-285180-32bxx94u	293	1	The	the	DT
cord-285180-32bxx94u	293	2	coronavirus	coronavirus	NN
cord-285180-32bxx94u	293	3	infectious	infectious	JJ
cord-285180-32bxx94u	293	4	bronchitis	bronchitis	NN
cord-285180-32bxx94u	293	5	virus	virus	NN
cord-285180-32bxx94u	293	6	nucleoprotein	nucleoprotein	NNP
cord-285180-32bxx94u	293	7	localizes	localize	VBZ
cord-285180-32bxx94u	293	8	to	to	IN
cord-285180-32bxx94u	293	9	the	the	DT
cord-285180-32bxx94u	293	10	nucleolus	nucleolus	NN
cord-285180-32bxx94u	293	11	A	a	DT
cord-285180-32bxx94u	293	12	role	role	NN
cord-285180-32bxx94u	293	13	for	for	IN
cord-285180-32bxx94u	293	14	molecular	molecular	JJ
cord-285180-32bxx94u	293	15	chaperone	chaperone	NN
cord-285180-32bxx94u	293	16	Hsc70	Hsc70	NNP
cord-285180-32bxx94u	293	17	in	in	IN
cord-285180-32bxx94u	293	18	reovirus	reovirus	NNP
cord-285180-32bxx94u	293	19	outer	outer	JJ
cord-285180-32bxx94u	293	20	capsid	capsid	NN
cord-285180-32bxx94u	293	21	disassembly	disassembly	NN
cord-285180-32bxx94u	293	22	Quantitative	quantitative	JJ
cord-285180-32bxx94u	293	23	analysis	analysis	NN
cord-285180-32bxx94u	293	24	of	of	IN
cord-285180-32bxx94u	293	25	severe	severe	JJ
cord-285180-32bxx94u	293	26	acute	acute	JJ
cord-285180-32bxx94u	293	27	respiratory	respiratory	JJ
cord-285180-32bxx94u	293	28	syndrome	syndrome	NN
cord-285180-32bxx94u	293	29	(	(	-LRB-
cord-285180-32bxx94u	293	30	SARS)-associated	sars)-associated	CD
cord-285180-32bxx94u	293	31	coronavirus	coronavirus	NN
cord-285180-32bxx94u	293	32	-	-	HYPH
cord-285180-32bxx94u	293	33	infected	infect	VBN
cord-285180-32bxx94u	293	34	cells	cell	NNS
cord-285180-32bxx94u	293	35	using	use	VBG
cord-285180-32bxx94u	293	36	proteomic	proteomic	JJ
cord-285180-32bxx94u	293	37	approaches	approach	NNS
cord-285180-32bxx94u	293	38	:	:	:
cord-285180-32bxx94u	293	39	implications	implication	NNS
cord-285180-32bxx94u	293	40	for	for	IN
cord-285180-32bxx94u	293	41	cellular	cellular	JJ
cord-285180-32bxx94u	293	42	responses	response	NNS
cord-285180-32bxx94u	293	43	to	to	IN
cord-285180-32bxx94u	293	44	virus	virus	NN
cord-285180-32bxx94u	293	45	infection	infection	NN
cord-285180-32bxx94u	293	46	Pathogenicity	Pathogenicity	NNP
cord-285180-32bxx94u	293	47	of	of	IN
cord-285180-32bxx94u	293	48	2	2	CD
cord-285180-32bxx94u	293	49	porcine	porcine	JJ
cord-285180-32bxx94u	293	50	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	293	51	strains	strain	NNS
cord-285180-32bxx94u	293	52	in	in	IN
cord-285180-32bxx94u	293	53	gnotobiotic	gnotobiotic	JJ
cord-285180-32bxx94u	293	54	pigs	pig	NNS
cord-285180-32bxx94u	294	1	Ribavirin	ribavirin	RB
cord-285180-32bxx94u	294	2	efficiently	efficiently	RB
cord-285180-32bxx94u	294	3	suppresses	suppress	VBZ
cord-285180-32bxx94u	294	4	porcine	porcine	JJ
cord-285180-32bxx94u	294	5	nidovirus	nidovirus	NN
cord-285180-32bxx94u	294	6	replication	replication	NN
cord-285180-32bxx94u	294	7	Coronaviridae	Coronaviridae	NNP
cord-285180-32bxx94u	295	1	The	the	DT
cord-285180-32bxx94u	295	2	nuclear	nuclear	JJ
cord-285180-32bxx94u	295	3	localization	localization	NN
cord-285180-32bxx94u	295	4	signal	signal	NN
cord-285180-32bxx94u	295	5	of	of	IN
cord-285180-32bxx94u	295	6	the	the	DT
cord-285180-32bxx94u	295	7	PRRS	PRRS	NNP
cord-285180-32bxx94u	295	8	virus	virus	NN
cord-285180-32bxx94u	295	9	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	295	10	protein	protein	NN
cord-285180-32bxx94u	295	11	viral	viral	JJ
cord-285180-32bxx94u	295	12	replication	replication	NN
cord-285180-32bxx94u	295	13	in	in	IN
cord-285180-32bxx94u	295	14	vitro	vitro	FW
cord-285180-32bxx94u	295	15	and	and	CC
cord-285180-32bxx94u	295	16	antibody	antibody	NN
cord-285180-32bxx94u	295	17	response	response	NN
cord-285180-32bxx94u	295	18	in	in	IN
cord-285180-32bxx94u	295	19	vivo	vivo	NNP
cord-285180-32bxx94u	295	20	Complete	complete	JJ
cord-285180-32bxx94u	295	21	genome	genome	NN
cord-285180-32bxx94u	295	22	characterization	characterization	NN
cord-285180-32bxx94u	295	23	of	of	IN
cord-285180-32bxx94u	295	24	Korean	korean	JJ
cord-285180-32bxx94u	295	25	porcine	porcine	JJ
cord-285180-32bxx94u	295	26	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	295	27	strain	strain	VBP
cord-285180-32bxx94u	295	28	KOR	KOR	NNP
cord-285180-32bxx94u	295	29	/	/	SYM
cord-285180-32bxx94u	295	30	KNU14	KNU14	NNP
cord-285180-32bxx94u	295	31	-	-	HYPH
cord-285180-32bxx94u	295	32	04/2014	04/2014	CD
cord-285180-32bxx94u	296	1	The	the	DT
cord-285180-32bxx94u	296	2	small	small	JJ
cord-285180-32bxx94u	296	3	envelope	envelope	NN
cord-285180-32bxx94u	296	4	protein	protein	NN
cord-285180-32bxx94u	296	5	of	of	IN
cord-285180-32bxx94u	296	6	porcine	porcine	JJ
cord-285180-32bxx94u	296	7	reproductive	reproductive	JJ
cord-285180-32bxx94u	296	8	and	and	CC
cord-285180-32bxx94u	296	9	respiratory	respiratory	JJ
cord-285180-32bxx94u	296	10	syndrome	syndrome	NN
cord-285180-32bxx94u	296	11	virus	virus	NN
cord-285180-32bxx94u	296	12	possesses	possess	VBZ
cord-285180-32bxx94u	296	13	ion	ion	NN
cord-285180-32bxx94u	296	14	channel	channel	NN
cord-285180-32bxx94u	296	15	protein	protein	NN
cord-285180-32bxx94u	296	16	-	-	HYPH
cord-285180-32bxx94u	296	17	like	like	JJ
cord-285180-32bxx94u	296	18	properties	property	NNS
cord-285180-32bxx94u	296	19	Generation	generation	NN
cord-285180-32bxx94u	296	20	of	of	IN
cord-285180-32bxx94u	296	21	a	a	DT
cord-285180-32bxx94u	296	22	porcine	porcine	JJ
cord-285180-32bxx94u	296	23	alveolar	alveolar	NN
cord-285180-32bxx94u	296	24	macrophage	macrophage	NN
cord-285180-32bxx94u	296	25	cell	cell	NN
cord-285180-32bxx94u	296	26	line	line	NN
cord-285180-32bxx94u	296	27	for	for	IN
cord-285180-32bxx94u	296	28	the	the	DT
cord-285180-32bxx94u	296	29	growth	growth	NN
cord-285180-32bxx94u	296	30	of	of	IN
cord-285180-32bxx94u	296	31	porcine	porcine	JJ
cord-285180-32bxx94u	296	32	reproductive	reproductive	JJ
cord-285180-32bxx94u	296	33	and	and	CC
cord-285180-32bxx94u	296	34	respiratory	respiratory	JJ
cord-285180-32bxx94u	296	35	syndrome	syndrome	NN
cord-285180-32bxx94u	296	36	virus	virus	NN
cord-285180-32bxx94u	296	37	Full	full	JJ
cord-285180-32bxx94u	296	38	-	-	HYPH
cord-285180-32bxx94u	296	39	length	length	NN
cord-285180-32bxx94u	296	40	genome	genome	NN
cord-285180-32bxx94u	296	41	sequence	sequence	NN
cord-285180-32bxx94u	296	42	of	of	IN
cord-285180-32bxx94u	296	43	porcine	porcine	JJ
cord-285180-32bxx94u	296	44	deltacoronavirus	deltacoronavirus	NNP
cord-285180-32bxx94u	296	45	strain	strain	VBP
cord-285180-32bxx94u	296	46	USA	USA	NNP
cord-285180-32bxx94u	296	47	/	/	SYM
cord-285180-32bxx94u	296	48	IA/2014/8734	IA/2014/8734	NNP
cord-285180-32bxx94u	296	49	Analysis	Analysis	NNP
cord-285180-32bxx94u	296	50	of	of	IN
cord-285180-32bxx94u	296	51	relative	relative	JJ
cord-285180-32bxx94u	296	52	gene	gene	NN
cord-285180-32bxx94u	296	53	expression	expression	NN
cord-285180-32bxx94u	296	54	data	datum	NNS
cord-285180-32bxx94u	296	55	using	use	VBG
cord-285180-32bxx94u	296	56	real	real	JJ
cord-285180-32bxx94u	296	57	-	-	HYPH
cord-285180-32bxx94u	296	58	time	time	NN
cord-285180-32bxx94u	296	59	quantitative	quantitative	JJ
cord-285180-32bxx94u	296	60	PCR	PCR	NNP
cord-285180-32bxx94u	296	61	and	and	CC
cord-285180-32bxx94u	296	62	the	the	DT
cord-285180-32bxx94u	296	63	2(−Delta	2(−delta	JJ
cord-285180-32bxx94u	296	64	Delta	Delta	NNP
cord-285180-32bxx94u	296	65	C(T	C(T	NNP
cord-285180-32bxx94u	296	66	)	)	-RRB-
cord-285180-32bxx94u	296	67	)	)	-RRB-
cord-285180-32bxx94u	297	1	method	method	NN
cord-285180-32bxx94u	297	2	Heat	Heat	NNP
cord-285180-32bxx94u	297	3	shock	shock	NN
cord-285180-32bxx94u	297	4	cognate	cognate	NNP
cord-285180-32bxx94u	297	5	71	71	CD
cord-285180-32bxx94u	297	6	(	(	-LRB-
cord-285180-32bxx94u	297	7	HSC71	HSC71	NNP
cord-285180-32bxx94u	297	8	)	)	-RRB-
cord-285180-32bxx94u	297	9	regulates	regulate	VBZ
cord-285180-32bxx94u	297	10	cellular	cellular	JJ
cord-285180-32bxx94u	297	11	antiviral	antiviral	JJ
cord-285180-32bxx94u	297	12	response	response	NN
cord-285180-32bxx94u	297	13	by	by	IN
cord-285180-32bxx94u	297	14	impairing	impair	VBG
cord-285180-32bxx94u	297	15	formation	formation	NN
cord-285180-32bxx94u	297	16	of	of	IN
cord-285180-32bxx94u	297	17	VISA	VISA	NNP
cord-285180-32bxx94u	297	18	aggregates	aggregate	NNS
cord-285180-32bxx94u	297	19	Complete	complete	JJ
cord-285180-32bxx94u	297	20	genome	genome	NN
cord-285180-32bxx94u	297	21	sequence	sequence	NN
cord-285180-32bxx94u	297	22	of	of	IN
cord-285180-32bxx94u	297	23	strain	strain	NN
cord-285180-32bxx94u	297	24	SDCV	SDCV	NNP
cord-285180-32bxx94u	297	25	/	/	SYM
cord-285180-32bxx94u	297	26	USA	USA	NNP
cord-285180-32bxx94u	297	27	/	/	SYM
cord-285180-32bxx94u	297	28	Illinois121/2014	Illinois121/2014	NNS
cord-285180-32bxx94u	297	29	,	,	,
cord-285180-32bxx94u	297	30	a	a	DT
cord-285180-32bxx94u	297	31	porcine	porcine	JJ
cord-285180-32bxx94u	297	32	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	297	33	from	from	IN
cord-285180-32bxx94u	297	34	the	the	DT
cord-285180-32bxx94u	297	35	United	United	NNP
cord-285180-32bxx94u	297	36	States	States	NNP
cord-285180-32bxx94u	297	37	Rapid	Rapid	NNP
cord-285180-32bxx94u	297	38	detection	detection	NN
cord-285180-32bxx94u	297	39	,	,	,
cord-285180-32bxx94u	297	40	complete	complete	JJ
cord-285180-32bxx94u	297	41	genome	genome	NN
cord-285180-32bxx94u	297	42	sequencing	sequencing	NN
cord-285180-32bxx94u	297	43	,	,	,
cord-285180-32bxx94u	297	44	and	and	CC
cord-285180-32bxx94u	297	45	phylogenetic	phylogenetic	JJ
cord-285180-32bxx94u	297	46	analysis	analysis	NN
cord-285180-32bxx94u	297	47	of	of	IN
cord-285180-32bxx94u	297	48	porcine	porcine	JJ
cord-285180-32bxx94u	297	49	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	298	1	The	the	DT
cord-285180-32bxx94u	298	2	coronavirus	coronavirus	NN
cord-285180-32bxx94u	298	3	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	298	4	is	be	VBZ
cord-285180-32bxx94u	298	5	a	a	DT
cord-285180-32bxx94u	298	6	multifunctional	multifunctional	JJ
cord-285180-32bxx94u	298	7	protein	protein	NN
cord-285180-32bxx94u	298	8	New	New	NNP
cord-285180-32bxx94u	298	9	tricks	trick	NNS
cord-285180-32bxx94u	298	10	for	for	IN
cord-285180-32bxx94u	298	11	an	an	DT
cord-285180-32bxx94u	298	12	old	old	JJ
cord-285180-32bxx94u	298	13	dog	dog	NN
cord-285180-32bxx94u	298	14	:	:	:
cord-285180-32bxx94u	298	15	the	the	DT
cord-285180-32bxx94u	298	16	evolving	evolve	VBG
cord-285180-32bxx94u	298	17	world	world	NN
cord-285180-32bxx94u	298	18	of	of	IN
cord-285180-32bxx94u	298	19	Hsp70	Hsp70	NNP
cord-285180-32bxx94u	298	20	Moesin	Moesin	NNP
cord-285180-32bxx94u	298	21	regulates	regulate	VBZ
cord-285180-32bxx94u	298	22	stable	stable	JJ
cord-285180-32bxx94u	298	23	microtubule	microtubule	JJ
cord-285180-32bxx94u	298	24	formation	formation	NN
cord-285180-32bxx94u	298	25	and	and	CC
cord-285180-32bxx94u	298	26	limits	limit	NNS
cord-285180-32bxx94u	298	27	retroviral	retroviral	JJ
cord-285180-32bxx94u	298	28	infection	infection	NN
cord-285180-32bxx94u	298	29	in	in	IN
cord-285180-32bxx94u	298	30	cultured	cultured	JJ
cord-285180-32bxx94u	298	31	cells	cell	NNS
cord-285180-32bxx94u	298	32	Contribution	Contribution	NNP
cord-285180-32bxx94u	298	33	of	of	IN
cord-285180-32bxx94u	298	34	the	the	DT
cord-285180-32bxx94u	298	35	porcine	porcine	JJ
cord-285180-32bxx94u	298	36	aminopeptidase	aminopeptidase	NN
cord-285180-32bxx94u	298	37	N	N	NNP
cord-285180-32bxx94u	298	38	(	(	-LRB-
cord-285180-32bxx94u	298	39	CD13	CD13	NNP
cord-285180-32bxx94u	298	40	)	)	-RRB-
cord-285180-32bxx94u	298	41	receptor	receptor	NN
cord-285180-32bxx94u	298	42	density	density	NN
cord-285180-32bxx94u	298	43	to	to	IN
cord-285180-32bxx94u	298	44	porcine	porcine	JJ
cord-285180-32bxx94u	298	45	epidemic	epidemic	NN
cord-285180-32bxx94u	298	46	diarrhea	diarrhea	NN
cord-285180-32bxx94u	298	47	virus	virus	NN
cord-285180-32bxx94u	298	48	infection	infection	NN
cord-285180-32bxx94u	298	49	Proteomics	Proteomics	NNP
cord-285180-32bxx94u	298	50	analysis	analysis	NN
cord-285180-32bxx94u	298	51	unravels	unravel	VBZ
cord-285180-32bxx94u	298	52	the	the	DT
cord-285180-32bxx94u	298	53	functional	functional	JJ
cord-285180-32bxx94u	298	54	repertoire	repertoire	NN
cord-285180-32bxx94u	298	55	of	of	IN
cord-285180-32bxx94u	298	56	coronavirus	coronavirus	NN
cord-285180-32bxx94u	298	57	nonstructural	nonstructural	JJ
cord-285180-32bxx94u	298	58	protein	protein	NN
cord-285180-32bxx94u	298	59	3	3	CD
cord-285180-32bxx94u	298	60	A	a	DT
cord-285180-32bxx94u	298	61	simplified	simplified	JJ
cord-285180-32bxx94u	298	62	ultrasensitive	ultrasensitive	JJ
cord-285180-32bxx94u	298	63	silver	silver	NN
cord-285180-32bxx94u	298	64	stain	stain	NN
cord-285180-32bxx94u	298	65	for	for	IN
cord-285180-32bxx94u	298	66	detecting	detect	VBG
cord-285180-32bxx94u	298	67	proteins	protein	NNS
cord-285180-32bxx94u	298	68	in	in	IN
cord-285180-32bxx94u	298	69	polyacrylamide	polyacrylamide	NN
cord-285180-32bxx94u	298	70	gels	gel	NNS
cord-285180-32bxx94u	299	1	Proteomic	proteomic	JJ
cord-285180-32bxx94u	299	2	characterization	characterization	NN
cord-285180-32bxx94u	299	3	of	of	IN
cord-285180-32bxx94u	299	4	a	a	DT
cord-285180-32bxx94u	299	5	novel	novel	JJ
cord-285180-32bxx94u	299	6	structural	structural	JJ
cord-285180-32bxx94u	299	7	protein	protein	NN
cord-285180-32bxx94u	299	8	ORF5a	ORF5a	NNP
cord-285180-32bxx94u	299	9	of	of	IN
cord-285180-32bxx94u	299	10	porcine	porcine	JJ
cord-285180-32bxx94u	299	11	reproductive	reproductive	JJ
cord-285180-32bxx94u	299	12	and	and	CC
cord-285180-32bxx94u	299	13	respiratory	respiratory	JJ
cord-285180-32bxx94u	299	14	syndrome	syndrome	NN
cord-285180-32bxx94u	299	15	virus	virus	NN
cord-285180-32bxx94u	299	16	Dual	dual	JJ
cord-285180-32bxx94u	299	17	targeting	targeting	NN
cord-285180-32bxx94u	299	18	of	of	IN
cord-285180-32bxx94u	299	19	HSC70	HSC70	NNP
cord-285180-32bxx94u	300	1	and	and	CC
cord-285180-32bxx94u	300	2	HSP72	HSP72	NNP
cord-285180-32bxx94u	300	3	inhibits	inhibit	VBZ
cord-285180-32bxx94u	300	4	HSP90	hsp90	JJ
cord-285180-32bxx94u	300	5	function	function	NN
cord-285180-32bxx94u	300	6	and	and	CC
cord-285180-32bxx94u	300	7	induces	induce	VBZ
cord-285180-32bxx94u	300	8	tumor	tumor	NN
cord-285180-32bxx94u	300	9	-	-	HYPH
cord-285180-32bxx94u	300	10	specific	specific	JJ
cord-285180-32bxx94u	300	11	apoptosis	apoptosis	NN
cord-285180-32bxx94u	300	12	Protein	protein	NN
cord-285180-32bxx94u	300	13	analysis	analysis	NN
cord-285180-32bxx94u	300	14	of	of	IN
cord-285180-32bxx94u	300	15	purified	purify	VBN
cord-285180-32bxx94u	300	16	respiratory	respiratory	JJ
cord-285180-32bxx94u	300	17	syncytial	syncytial	JJ
cord-285180-32bxx94u	300	18	virus	virus	NN
cord-285180-32bxx94u	300	19	particles	particle	NNS
cord-285180-32bxx94u	301	1	reveals	reveal	VBZ
cord-285180-32bxx94u	301	2	an	an	DT
cord-285180-32bxx94u	301	3	important	important	JJ
cord-285180-32bxx94u	301	4	role	role	NN
cord-285180-32bxx94u	301	5	for	for	IN
cord-285180-32bxx94u	301	6	heat	heat	NN
cord-285180-32bxx94u	301	7	shock	shock	NN
cord-285180-32bxx94u	301	8	protein	protein	NN
cord-285180-32bxx94u	301	9	90	90	CD
cord-285180-32bxx94u	301	10	in	in	IN
cord-285180-32bxx94u	301	11	virus	virus	NN
cord-285180-32bxx94u	301	12	particle	particle	NN
cord-285180-32bxx94u	301	13	assembly	assembly	NN
cord-285180-32bxx94u	301	14	Proteomic	Proteomic	NNP
cord-285180-32bxx94u	301	15	studies	study	NNS
cord-285180-32bxx94u	301	16	reveal	reveal	VBP
cord-285180-32bxx94u	301	17	coordinated	coordinated	JJ
cord-285180-32bxx94u	301	18	changes	change	NNS
cord-285180-32bxx94u	301	19	in	in	IN
cord-285180-32bxx94u	301	20	T	t	NN
cord-285180-32bxx94u	301	21	-	-	HYPH
cord-285180-32bxx94u	301	22	cell	cell	NN
cord-285180-32bxx94u	301	23	expression	expression	NN
cord-285180-32bxx94u	301	24	patterns	pattern	NNS
cord-285180-32bxx94u	301	25	upon	upon	IN
cord-285180-32bxx94u	301	26	infection	infection	NN
cord-285180-32bxx94u	301	27	with	with	IN
cord-285180-32bxx94u	301	28	human	human	JJ
cord-285180-32bxx94u	301	29	immunodeficiency	immunodeficiency	NN
cord-285180-32bxx94u	301	30	virus	virus	NN
cord-285180-32bxx94u	301	31	type	type	NN
cord-285180-32bxx94u	301	32	1	1	CD
cord-285180-32bxx94u	301	33	Signal	Signal	NNP
cord-285180-32bxx94u	301	34	integration	integration	NN
cord-285180-32bxx94u	301	35	in	in	IN
cord-285180-32bxx94u	301	36	the	the	DT
cord-285180-32bxx94u	301	37	endoplasmic	endoplasmic	NN
cord-285180-32bxx94u	301	38	reticulum	reticulum	NN
cord-285180-32bxx94u	301	39	unfolded	unfold	VBD
cord-285180-32bxx94u	301	40	protein	protein	NN
cord-285180-32bxx94u	301	41	response	response	NN
cord-285180-32bxx94u	301	42	Differential	differential	JJ
cord-285180-32bxx94u	301	43	cellular	cellular	JJ
cord-285180-32bxx94u	301	44	expression	expression	NN
cord-285180-32bxx94u	301	45	in	in	IN
cord-285180-32bxx94u	301	46	continuous	continuous	JJ
cord-285180-32bxx94u	301	47	porcine	porcine	JJ
cord-285180-32bxx94u	301	48	alveolar	alveolar	NN
cord-285180-32bxx94u	301	49	macrophages	macrophage	NNS
cord-285180-32bxx94u	301	50	regulated	regulate	VBN
cord-285180-32bxx94u	301	51	by	by	IN
cord-285180-32bxx94u	301	52	the	the	DT
cord-285180-32bxx94u	301	53	porcine	porcine	JJ
cord-285180-32bxx94u	301	54	reproductive	reproductive	JJ
cord-285180-32bxx94u	301	55	and	and	CC
cord-285180-32bxx94u	301	56	respiratory	respiratory	JJ
cord-285180-32bxx94u	301	57	syndrome	syndrome	NN
cord-285180-32bxx94u	301	58	virus	virus	NN
cord-285180-32bxx94u	301	59	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	301	60	protein	protein	NN
cord-285180-32bxx94u	301	61	Porcine	porcine	JJ
cord-285180-32bxx94u	301	62	reproductive	reproductive	JJ
cord-285180-32bxx94u	301	63	and	and	CC
cord-285180-32bxx94u	301	64	respiratory	respiratory	JJ
cord-285180-32bxx94u	301	65	syndrome	syndrome	NN
cord-285180-32bxx94u	301	66	virus	virus	NN
cord-285180-32bxx94u	301	67	nucleocapsid	nucleocapsid	NNP
cord-285180-32bxx94u	301	68	protein	protein	NN
cord-285180-32bxx94u	301	69	modulates	modulate	VBZ
cord-285180-32bxx94u	301	70	interferon-	interferon-	NN
cord-285180-32bxx94u	301	71	␤	␤	CD
cord-285180-32bxx94u	301	72	production	production	NN
cord-285180-32bxx94u	301	73	by	by	IN
cord-285180-32bxx94u	301	74	inhibiting	inhibit	VBG
cord-285180-32bxx94u	301	75	IRF3	IRF3	NNP
cord-285180-32bxx94u	301	76	activation	activation	NN
cord-285180-32bxx94u	301	77	in	in	IN
cord-285180-32bxx94u	301	78	immortalized	immortalize	VBN
cord-285180-32bxx94u	301	79	porcine	porcine	JJ
cord-285180-32bxx94u	301	80	alveolar	alveolar	NN
cord-285180-32bxx94u	301	81	macrophages	macrophage	NNS
cord-285180-32bxx94u	301	82	Molecular	Molecular	NNP
cord-285180-32bxx94u	301	83	Cloning	Cloning	NNP
cord-285180-32bxx94u	301	84	:	:	:
cord-285180-32bxx94u	301	85	A	a	DT
cord-285180-32bxx94u	301	86	Laboratory	Laboratory	NNP
cord-285180-32bxx94u	301	87	Manual	Manual	NNP
cord-285180-32bxx94u	301	88	Mass	Mass	NNP
cord-285180-32bxx94u	301	89	spectrometric	spectrometric	JJ
cord-285180-32bxx94u	301	90	sequencing	sequencing	NN
cord-285180-32bxx94u	301	91	of	of	IN
cord-285180-32bxx94u	301	92	proteins	protein	NNS
cord-285180-32bxx94u	301	93	silver	silver	NN
cord-285180-32bxx94u	301	94	-	-	HYPH
cord-285180-32bxx94u	301	95	stained	stain	VBN
cord-285180-32bxx94u	301	96	polyacrylamide	polyacrylamide	NN
cord-285180-32bxx94u	301	97	gels	gel	NNS
cord-285180-32bxx94u	302	1	An	an	DT
cord-285180-32bxx94u	302	2	evolutionarily	evolutionarily	RB
cord-285180-32bxx94u	302	3	conserved	conserved	JJ
cord-285180-32bxx94u	302	4	family	family	NN
cord-285180-32bxx94u	302	5	of	of	IN
cord-285180-32bxx94u	302	6	Hsp70	Hsp70	NNP
cord-285180-32bxx94u	302	7	/	/	SYM
cord-285180-32bxx94u	302	8	Hsc70	Hsc70	NNP
cord-285180-32bxx94u	302	9	molecular	molecular	JJ
cord-285180-32bxx94u	302	10	chaperone	chaperone	NN
cord-285180-32bxx94u	302	11	regulators	regulator	NNS
cord-285180-32bxx94u	302	12	Detection	Detection	NNP
cord-285180-32bxx94u	302	13	and	and	CC
cord-285180-32bxx94u	302	14	genetic	genetic	JJ
cord-285180-32bxx94u	302	15	characterization	characterization	NN
cord-285180-32bxx94u	302	16	of	of	IN
cord-285180-32bxx94u	302	17	deltacoronavirus	deltacoronavirus	NN
cord-285180-32bxx94u	302	18	in	in	IN
cord-285180-32bxx94u	302	19	pigs	pig	NNS
cord-285180-32bxx94u	302	20	Identification	Identification	NNP
cord-285180-32bxx94u	302	21	of	of	IN
cord-285180-32bxx94u	302	22	Hsc70	Hsc70	NNP
cord-285180-32bxx94u	302	23	as	as	IN
cord-285180-32bxx94u	302	24	an	an	DT
cord-285180-32bxx94u	302	25	influenza	influenza	NN
cord-285180-32bxx94u	302	26	virus	virus	NN
cord-285180-32bxx94u	302	27	matrix	matrix	NN
cord-285180-32bxx94u	302	28	protein	protein	NN
cord-285180-32bxx94u	302	29	(	(	-LRB-
cord-285180-32bxx94u	302	30	M1	M1	NNP
cord-285180-32bxx94u	302	31	)	)	-RRB-
cord-285180-32bxx94u	302	32	binding	binding	NN
cord-285180-32bxx94u	302	33	factor	factor	NN
cord-285180-32bxx94u	302	34	involved	involve	VBN
cord-285180-32bxx94u	302	35	in	in	IN
cord-285180-32bxx94u	302	36	the	the	DT
cord-285180-32bxx94u	302	37	virus	virus	NN
cord-285180-32bxx94u	302	38	life	life	NN
cord-285180-32bxx94u	302	39	cycle	cycle	NN
cord-285180-32bxx94u	302	40	Nuclear	nuclear	JJ
cord-285180-32bxx94u	302	41	export	export	NN
cord-285180-32bxx94u	302	42	of	of	IN
cord-285180-32bxx94u	302	43	the	the	DT
cord-285180-32bxx94u	302	44	influenza	influenza	NN
cord-285180-32bxx94u	302	45	virus	virus	NN
cord-285180-32bxx94u	302	46	ribonucleoprotein	ribonucleoprotein	NNP
cord-285180-32bxx94u	302	47	complex	complex	NN
cord-285180-32bxx94u	302	48	:	:	:
cord-285180-32bxx94u	303	1	interaction	interaction	NN
cord-285180-32bxx94u	303	2	of	of	IN
cord-285180-32bxx94u	303	3	Hsc70	Hsc70	NNP
cord-285180-32bxx94u	303	4	with	with	IN
cord-285180-32bxx94u	303	5	viral	viral	JJ
cord-285180-32bxx94u	303	6	proteins	protein	NNS
cord-285180-32bxx94u	303	7	M1	M1	NNP
cord-285180-32bxx94u	303	8	and	and	CC
cord-285180-32bxx94u	303	9	NS2	NS2	NNP
cord-285180-32bxx94u	303	10	Discovery	Discovery	NNP
cord-285180-32bxx94u	303	11	of	of	IN
cord-285180-32bxx94u	303	12	seven	seven	CD
cord-285180-32bxx94u	303	13	novel	novel	JJ
cord-285180-32bxx94u	303	14	mammalian	mammalian	JJ
cord-285180-32bxx94u	303	15	and	and	CC
cord-285180-32bxx94u	303	16	avian	avian	JJ
cord-285180-32bxx94u	303	17	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	303	18	in	in	IN
cord-285180-32bxx94u	303	19	the	the	DT
cord-285180-32bxx94u	303	20	genus	genus	NN
cord-285180-32bxx94u	303	21	deltacoronavirus	deltacoronavirus	NNP
cord-285180-32bxx94u	303	22	supports	support	VBZ
cord-285180-32bxx94u	303	23	bat	bat	NN
cord-285180-32bxx94u	303	24	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	303	25	as	as	IN
cord-285180-32bxx94u	303	26	the	the	DT
cord-285180-32bxx94u	303	27	gene	gene	NN
cord-285180-32bxx94u	303	28	source	source	NN
cord-285180-32bxx94u	303	29	of	of	IN
cord-285180-32bxx94u	303	30	alphacoronavirus	alphacoronavirus	NNP
cord-285180-32bxx94u	303	31	and	and	CC
cord-285180-32bxx94u	303	32	betacoronavirus	betacoronavirus	NNP
cord-285180-32bxx94u	303	33	and	and	CC
cord-285180-32bxx94u	303	34	avian	avian	JJ
cord-285180-32bxx94u	303	35	coronaviruses	coronaviruse	NNS
cord-285180-32bxx94u	303	36	as	as	IN
cord-285180-32bxx94u	303	37	the	the	DT
cord-285180-32bxx94u	303	38	gene	gene	NN
cord-285180-32bxx94u	303	39	source	source	NN
cord-285180-32bxx94u	303	40	of	of	IN
cord-285180-32bxx94u	303	41	gammacoronavirus	gammacoronavirus	NNP
cord-285180-32bxx94u	303	42	and	and	CC
cord-285180-32bxx94u	303	43	deltacoronavirus	deltacoronavirus	JJ
cord-285180-32bxx94u	303	44	Homo	homo	NN
cord-285180-32bxx94u	303	45	-	-	HYPH
cord-285180-32bxx94u	303	46	oligomerization	oligomerization	NN
cord-285180-32bxx94u	303	47	of	of	IN
cord-285180-32bxx94u	303	48	the	the	DT
cord-285180-32bxx94u	303	49	porcine	porcine	JJ
cord-285180-32bxx94u	303	50	reproductive	reproductive	JJ
cord-285180-32bxx94u	303	51	and	and	CC
cord-285180-32bxx94u	303	52	respiratory	respiratory	JJ
cord-285180-32bxx94u	303	53	syndrome	syndrome	NN
cord-285180-32bxx94u	303	54	virus	virus	NN
cord-285180-32bxx94u	303	55	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	303	56	protein	protein	NNP
cord-285180-32bxx94u	303	57	and	and	CC
cord-285180-32bxx94u	303	58	the	the	DT
cord-285180-32bxx94u	303	59	role	role	NN
cord-285180-32bxx94u	303	60	of	of	IN
cord-285180-32bxx94u	303	61	disulfide	disulfide	JJ
cord-285180-32bxx94u	303	62	linkages	linkage	NNS
cord-285180-32bxx94u	303	63	Localization	Localization	NNP
cord-285180-32bxx94u	303	64	to	to	IN
cord-285180-32bxx94u	303	65	the	the	DT
cord-285180-32bxx94u	303	66	nucleolus	nucleolus	NN
cord-285180-32bxx94u	303	67	is	be	VBZ
cord-285180-32bxx94u	303	68	a	a	DT
cord-285180-32bxx94u	303	69	common	common	JJ
cord-285180-32bxx94u	303	70	feature	feature	NN
cord-285180-32bxx94u	303	71	of	of	IN
cord-285180-32bxx94u	303	72	coronavirus	coronavirus	NN
cord-285180-32bxx94u	303	73	nucleoproteins	nucleoprotein	NNS
cord-285180-32bxx94u	303	74	,	,	,
cord-285180-32bxx94u	303	75	and	and	CC
cord-285180-32bxx94u	303	76	the	the	DT
cord-285180-32bxx94u	303	77	protein	protein	NN
cord-285180-32bxx94u	303	78	may	may	MD
cord-285180-32bxx94u	303	79	disrupt	disrupt	VB
cord-285180-32bxx94u	303	80	host	host	NN
cord-285180-32bxx94u	303	81	cell	cell	NN
cord-285180-32bxx94u	303	82	division	division	NN
cord-285180-32bxx94u	303	83	Porcine	porcine	JJ
cord-285180-32bxx94u	303	84	epidemic	epidemic	NN
cord-285180-32bxx94u	303	85	diarrhea	diarrhea	NN
cord-285180-32bxx94u	304	1	N	n	NN
cord-285180-32bxx94u	304	2	protein	protein	NN
cord-285180-32bxx94u	304	3	prolongs	prolong	VBZ
cord-285180-32bxx94u	304	4	S	s	NN
cord-285180-32bxx94u	304	5	-	-	HYPH
cord-285180-32bxx94u	304	6	phase	phase	NN
cord-285180-32bxx94u	304	7	cell	cell	NN
cord-285180-32bxx94u	304	8	cycle	cycle	NN
cord-285180-32bxx94u	304	9	,	,	,
cord-285180-32bxx94u	304	10	induces	induce	VBZ
cord-285180-32bxx94u	304	11	endoplasmic	endoplasmic	NN
cord-285180-32bxx94u	304	12	reticulum	reticulum	NN
cord-285180-32bxx94u	304	13	stress	stress	NN
cord-285180-32bxx94u	304	14	,	,	,
cord-285180-32bxx94u	304	15	and	and	CC
cord-285180-32bxx94u	304	16	up	up	RB
cord-285180-32bxx94u	304	17	-	-	HYPH
cord-285180-32bxx94u	304	18	regulates	regulate	VBZ
cord-285180-32bxx94u	304	19	interleukin-8	interleukin-8	NNP
cord-285180-32bxx94u	304	20	expression	expression	NN
cord-285180-32bxx94u	304	21	Heat	Heat	NNP
cord-285180-32bxx94u	304	22	shock	shock	NN
cord-285180-32bxx94u	304	23	cognate	cognate	JJ
cord-285180-32bxx94u	304	24	protein	protein	NN
cord-285180-32bxx94u	304	25	70	70	CD
cord-285180-32bxx94u	304	26	gene	gene	NN
cord-285180-32bxx94u	304	27	is	be	VBZ
cord-285180-32bxx94u	304	28	required	require	VBN
cord-285180-32bxx94u	304	29	for	for	IN
cord-285180-32bxx94u	304	30	prevention	prevention	NN
cord-285180-32bxx94u	304	31	of	of	IN
cord-285180-32bxx94u	304	32	apoptosis	apoptosis	NN
cord-285180-32bxx94u	304	33	induced	induce	VBN
cord-285180-32bxx94u	304	34	by	by	IN
cord-285180-32bxx94u	304	35	WSSV	WSSV	NNP
cord-285180-32bxx94u	304	36	infection	infection	NN
cord-285180-32bxx94u	304	37	Glucose	glucose	NN
cord-285180-32bxx94u	304	38	-	-	HYPH
cord-285180-32bxx94u	304	39	regulated	regulate	VBN
cord-285180-32bxx94u	304	40	protein	protein	NN
cord-285180-32bxx94u	304	41	78	78	CD
cord-285180-32bxx94u	304	42	as	as	IN
cord-285180-32bxx94u	305	1	a	a	DT
cord-285180-32bxx94u	305	2	novel	novel	NN
cord-285180-32bxx94u	305	3	effector	effector	NN
cord-285180-32bxx94u	305	4	of	of	IN
cord-285180-32bxx94u	305	5	BRCA1	BRCA1	NNP
cord-285180-32bxx94u	305	6	for	for	IN
cord-285180-32bxx94u	305	7	inhibiting	inhibit	VBG
cord-285180-32bxx94u	305	8	stress	stress	NN
cord-285180-32bxx94u	305	9	-	-	HYPH
cord-285180-32bxx94u	305	10	induced	induce	VBN
cord-285180-32bxx94u	305	11	apoptosis	apoptosis	NN
cord-285180-32bxx94u	305	12	Colocalization	colocalization	NN
cord-285180-32bxx94u	305	13	and	and	CC
cord-285180-32bxx94u	305	14	interaction	interaction	NN
cord-285180-32bxx94u	305	15	of	of	IN
cord-285180-32bxx94u	305	16	the	the	DT
cord-285180-32bxx94u	305	17	porcine	porcine	JJ
cord-285180-32bxx94u	305	18	arterivirus	arterivirus	NNP
cord-285180-32bxx94u	305	19	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	305	20	protein	protein	NNP
cord-285180-32bxx94u	305	21	with	with	IN
cord-285180-32bxx94u	305	22	the	the	DT
cord-285180-32bxx94u	305	23	small	small	JJ
cord-285180-32bxx94u	305	24	nucleolar	nucleolar	JJ
cord-285180-32bxx94u	305	25	RNA	RNA	NNP
cord-285180-32bxx94u	305	26	-	-	HYPH
cord-285180-32bxx94u	305	27	associated	associate	VBN
cord-285180-32bxx94u	305	28	protein	protein	NN
cord-285180-32bxx94u	305	29	fibrillarin	fibrillarin	NNP
cord-285180-32bxx94u	305	30	Proteomic	Proteomic	NNP
cord-285180-32bxx94u	305	31	profiling	profiling	NN
cord-285180-32bxx94u	305	32	of	of	IN
cord-285180-32bxx94u	305	33	hepatitis	hepatitis	NN
cord-285180-32bxx94u	305	34	B	B	NNP
cord-285180-32bxx94u	305	35	virus	virus	NN
cord-285180-32bxx94u	305	36	-	-	HYPH
cord-285180-32bxx94u	305	37	related	relate	VBN
cord-285180-32bxx94u	305	38	hepatocellular	hepatocellular	JJ
cord-285180-32bxx94u	305	39	carcinoma	carcinoma	NN
cord-285180-32bxx94u	305	40	in	in	IN
cord-285180-32bxx94u	305	41	China	China	NNP
cord-285180-32bxx94u	305	42	:	:	:
cord-285180-32bxx94u	305	43	a	a	DT
cord-285180-32bxx94u	305	44	SELDI	SELDI	NNP
cord-285180-32bxx94u	305	45	-	-	HYPH
cord-285180-32bxx94u	305	46	TOF	TOF	NNP
cord-285180-32bxx94u	305	47	-	-	HYPH
cord-285180-32bxx94u	305	48	MS	MS	NNP
cord-285180-32bxx94u	305	49	study	study	NN
cord-285180-32bxx94u	305	50	Changes	change	NNS
cord-285180-32bxx94u	305	51	in	in	IN
cord-285180-32bxx94u	305	52	the	the	DT
cord-285180-32bxx94u	305	53	cellular	cellular	JJ
cord-285180-32bxx94u	305	54	proteins	protein	NNS
cord-285180-32bxx94u	305	55	of	of	IN
cord-285180-32bxx94u	305	56	pulmonary	pulmonary	JJ
cord-285180-32bxx94u	305	57	alveolar	alveolar	NN
cord-285180-32bxx94u	305	58	macrophage	macrophage	NN
cord-285180-32bxx94u	305	59	infected	infect	VBN
cord-285180-32bxx94u	305	60	with	with	IN
cord-285180-32bxx94u	305	61	porcine	porcine	JJ
cord-285180-32bxx94u	305	62	reproductive	reproductive	JJ
cord-285180-32bxx94u	305	63	and	and	CC
cord-285180-32bxx94u	305	64	respiratory	respiratory	JJ
cord-285180-32bxx94u	305	65	syndrome	syndrome	NN
cord-285180-32bxx94u	305	66	virus	virus	NN
cord-285180-32bxx94u	305	67	by	by	IN
cord-285180-32bxx94u	305	68	proteomics	proteomic	NNS
cord-285180-32bxx94u	305	69	analysis	analysis	NN
cord-285180-32bxx94u	306	1	The	the	DT
cord-285180-32bxx94u	306	2	nucleocapsid	nucleocapsid	NN
cord-285180-32bxx94u	306	3	protein	protein	NN
cord-285180-32bxx94u	306	4	of	of	IN
cord-285180-32bxx94u	306	5	severe	severe	JJ
cord-285180-32bxx94u	306	6	acute	acute	JJ
cord-285180-32bxx94u	306	7	respiratory	respiratory	JJ
cord-285180-32bxx94u	306	8	syndrome	syndrome	NN
cord-285180-32bxx94u	306	9	coronavirus	coronavirus	NN
cord-285180-32bxx94u	306	10	inhibits	inhibit	VBZ
cord-285180-32bxx94u	306	11	cell	cell	NN
cord-285180-32bxx94u	306	12	cytokinesis	cytokinesis	NN
cord-285180-32bxx94u	306	13	and	and	CC
cord-285180-32bxx94u	306	14	proliferation	proliferation	NN
cord-285180-32bxx94u	306	15	by	by	IN
cord-285180-32bxx94u	306	16	interacting	interact	VBG
cord-285180-32bxx94u	306	17	with	with	IN
cord-285180-32bxx94u	306	18	translation	translation	NN
cord-285180-32bxx94u	306	19	elongation	elongation	NN
cord-285180-32bxx94u	306	20	factor	factor	NN
cord-285180-32bxx94u	306	21	1alpha	1alpha	CD