id	sid	tid	token	lemma	pos
cord-300883-rws11uel	1	1	key	key	JJ
cord-300883-rws11uel	1	2	:	:	:
cord-300883-rws11uel	1	3	cord-300883-rws11uel	cord-300883-rws11uel	NNP
cord-300883-rws11uel	1	4	authors	author	NNS
cord-300883-rws11uel	1	5	:	:	:
cord-300883-rws11uel	1	6	Padhi	Padhi	NNP
cord-300883-rws11uel	1	7	,	,	,
cord-300883-rws11uel	1	8	Abinash	Abinash	NNP
cord-300883-rws11uel	1	9	;	;	:
cord-300883-rws11uel	1	10	Verghese	Verghese	NNP
cord-300883-rws11uel	1	11	,	,	,
cord-300883-rws11uel	1	12	Bindhu	Bindhu	NNP
cord-300883-rws11uel	1	13	title	title	NN
cord-300883-rws11uel	1	14	:	:	:
cord-300883-rws11uel	1	15	Positive	positive	JJ
cord-300883-rws11uel	1	16	natural	natural	JJ
cord-300883-rws11uel	1	17	selection	selection	NN
cord-300883-rws11uel	1	18	in	in	IN
cord-300883-rws11uel	1	19	the	the	DT
cord-300883-rws11uel	1	20	evolution	evolution	NN
cord-300883-rws11uel	1	21	of	of	IN
cord-300883-rws11uel	1	22	human	human	JJ
cord-300883-rws11uel	1	23	metapneumovirus	metapneumovirus	JJ
cord-300883-rws11uel	1	24	attachment	attachment	NN
cord-300883-rws11uel	1	25	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	1	26	date	date	NN
cord-300883-rws11uel	1	27	:	:	:
cord-300883-rws11uel	1	28	2007	2007	CD
cord-300883-rws11uel	1	29	-	-	SYM
cord-300883-rws11uel	1	30	10	10	CD
cord-300883-rws11uel	1	31	-	-	SYM
cord-300883-rws11uel	1	32	10	10	CD
cord-300883-rws11uel	1	33	journal	journal	NN
cord-300883-rws11uel	1	34	:	:	:
cord-300883-rws11uel	2	1	Virus	virus	NN
cord-300883-rws11uel	2	2	Res	res	NN
cord-300883-rws11uel	2	3	DOI	doi	NN
cord-300883-rws11uel	2	4	:	:	:
cord-300883-rws11uel	3	1	10.1016	10.1016	CD
cord-300883-rws11uel	3	2	/	/	SYM
cord-300883-rws11uel	3	3	j.virusres.2007.08.014	j.virusres.2007.08.014	NNS
cord-300883-rws11uel	3	4	sha	sha	XX
cord-300883-rws11uel	3	5	:	:	:
cord-300883-rws11uel	4	1	1996f69b64707265aa7598a82d3281c4b9d7aaf6	1996f69b64707265aa7598a82d3281c4b9d7aaf6	CD
cord-300883-rws11uel	4	2	doc_id	doc_id	CD
cord-300883-rws11uel	4	3	:	:	:
cord-300883-rws11uel	4	4	300883	300883	CD
cord-300883-rws11uel	4	5	cord_uid	cord_uid	NN
cord-300883-rws11uel	4	6	:	:	:
cord-300883-rws11uel	5	1	rws11uel	rws11uel	NNP
cord-300883-rws11uel	5	2	Human	Human	NNP
cord-300883-rws11uel	5	3	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	5	4	(	(	-LRB-
cord-300883-rws11uel	5	5	hMPV	hMPV	NNP
cord-300883-rws11uel	5	6	)	)	-RRB-
cord-300883-rws11uel	5	7	,	,	,
cord-300883-rws11uel	5	8	a	a	DT
cord-300883-rws11uel	5	9	newly	newly	RB
cord-300883-rws11uel	5	10	discovered	discover	VBN
cord-300883-rws11uel	5	11	virus	virus	NN
cord-300883-rws11uel	5	12	of	of	IN
cord-300883-rws11uel	5	13	the	the	DT
cord-300883-rws11uel	5	14	family	family	NN
cord-300883-rws11uel	5	15	Paramyxoviridae	Paramyxoviridae	NNP
cord-300883-rws11uel	5	16	,	,	,
cord-300883-rws11uel	5	17	has	have	VBZ
cord-300883-rws11uel	5	18	been	be	VBN
cord-300883-rws11uel	5	19	associated	associate	VBN
cord-300883-rws11uel	5	20	with	with	IN
cord-300883-rws11uel	5	21	upper	upper	JJ
cord-300883-rws11uel	5	22	and	and	CC
cord-300883-rws11uel	5	23	lower	low	JJR
cord-300883-rws11uel	5	24	respiratory	respiratory	JJ
cord-300883-rws11uel	5	25	tract	tract	NN
cord-300883-rws11uel	5	26	infections	infection	NNS
cord-300883-rws11uel	5	27	in	in	IN
cord-300883-rws11uel	5	28	different	different	JJ
cord-300883-rws11uel	5	29	age	age	NN
cord-300883-rws11uel	5	30	groups	group	NNS
cord-300883-rws11uel	5	31	in	in	IN
cord-300883-rws11uel	5	32	many	many	JJ
cord-300883-rws11uel	5	33	countries	country	NNS
cord-300883-rws11uel	5	34	.	.	.
cord-300883-rws11uel	6	1	The	the	DT
cord-300883-rws11uel	6	2	putative	putative	JJ
cord-300883-rws11uel	6	3	attachment	attachment	NN
cord-300883-rws11uel	6	4	(	(	-LRB-
cord-300883-rws11uel	6	5	G	g	NN
cord-300883-rws11uel	6	6	)	)	-RRB-
cord-300883-rws11uel	6	7	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	6	8	of	of	IN
cord-300883-rws11uel	6	9	this	this	DT
cord-300883-rws11uel	6	10	virus	virus	NN
cord-300883-rws11uel	6	11	was	be	VBD
cord-300883-rws11uel	6	12	previously	previously	RB
cord-300883-rws11uel	6	13	reported	report	VBN
cord-300883-rws11uel	6	14	to	to	TO
cord-300883-rws11uel	6	15	have	have	VB
cord-300883-rws11uel	6	16	shown	show	VBN
cord-300883-rws11uel	6	17	more	more	RBR
cord-300883-rws11uel	6	18	extensive	extensive	JJ
cord-300883-rws11uel	6	19	nucleotide	nucleotide	NN
cord-300883-rws11uel	6	20	and	and	CC
cord-300883-rws11uel	6	21	deduced	deduce	VBN
cord-300883-rws11uel	6	22	amino	amino	NN
cord-300883-rws11uel	6	23	acid	acid	NN
cord-300883-rws11uel	6	24	sequence	sequence	NN
cord-300883-rws11uel	6	25	polymorphism	polymorphism	NN
cord-300883-rws11uel	6	26	than	than	IN
cord-300883-rws11uel	6	27	any	any	DT
cord-300883-rws11uel	6	28	other	other	JJ
cord-300883-rws11uel	6	29	genomic	genomic	JJ
cord-300883-rws11uel	6	30	regions	region	NNS
cord-300883-rws11uel	6	31	of	of	IN
cord-300883-rws11uel	6	32	this	this	DT
cord-300883-rws11uel	6	33	virus	virus	NN
cord-300883-rws11uel	6	34	,	,	,
cord-300883-rws11uel	6	35	leading	lead	VBG
cord-300883-rws11uel	6	36	to	to	IN
cord-300883-rws11uel	6	37	four	four	CD
cord-300883-rws11uel	6	38	sub	sub	NN
cord-300883-rws11uel	6	39	-	-	NNS
cord-300883-rws11uel	6	40	lineages	lineage	NNS
cord-300883-rws11uel	6	41	.	.	.
cord-300883-rws11uel	7	1	Using	use	VBG
cord-300883-rws11uel	7	2	a	a	DT
cord-300883-rws11uel	7	3	maximum	maximum	JJ
cord-300883-rws11uel	7	4	likelihood	likelihood	NN
cord-300883-rws11uel	7	5	-	-	HYPH
cord-300883-rws11uel	7	6	based	base	VBN
cord-300883-rws11uel	7	7	codon	codon	NN
cord-300883-rws11uel	7	8	substitution	substitution	NN
cord-300883-rws11uel	7	9	model	model	NN
cord-300883-rws11uel	7	10	of	of	IN
cord-300883-rws11uel	7	11	sequence	sequence	NN
cord-300883-rws11uel	7	12	evolution	evolution	NN
cord-300883-rws11uel	7	13	,	,	,
cord-300883-rws11uel	7	14	here	here	RB
cord-300883-rws11uel	7	15	we	-PRON-	PRP
cord-300883-rws11uel	7	16	report	report	VBP
cord-300883-rws11uel	7	17	that	that	IN
cord-300883-rws11uel	7	18	sequences	sequence	NNS
cord-300883-rws11uel	7	19	of	of	IN
cord-300883-rws11uel	7	20	extracellular	extracellular	JJ
cord-300883-rws11uel	7	21	domain	domain	NN
cord-300883-rws11uel	7	22	of	of	IN
cord-300883-rws11uel	7	23	8	8	CD
cord-300883-rws11uel	7	24	amino	amino	NN
cord-300883-rws11uel	7	25	acid	acid	NN
cord-300883-rws11uel	7	26	sites	site	NNS
cord-300883-rws11uel	7	27	in	in	IN
cord-300883-rws11uel	7	28	lineage	lineage	NN
cord-300883-rws11uel	7	29	1a	1a	CD
cord-300883-rws11uel	7	30	,	,	,
cord-300883-rws11uel	7	31	and	and	CC
cord-300883-rws11uel	7	32	3	3	CD
cord-300883-rws11uel	7	33	amino	amino	NN
cord-300883-rws11uel	7	34	acid	acid	NN
cord-300883-rws11uel	7	35	sites	site	NNS
cord-300883-rws11uel	7	36	each	each	DT
cord-300883-rws11uel	7	37	in	in	IN
cord-300883-rws11uel	7	38	lineage	lineage	NN
cord-300883-rws11uel	7	39	1b	1b	CD
cord-300883-rws11uel	7	40	,	,	,
cord-300883-rws11uel	7	41	2a	2a	CD
cord-300883-rws11uel	7	42	,	,	,
cord-300883-rws11uel	7	43	and	and	CC
cord-300883-rws11uel	7	44	2b	2b	CD
cord-300883-rws11uel	7	45	have	have	VBP
cord-300883-rws11uel	7	46	a	a	DT
cord-300883-rws11uel	7	47	higher	high	JJR
cord-300883-rws11uel	7	48	rate	rate	NN
cord-300883-rws11uel	7	49	of	of	IN
cord-300883-rws11uel	7	50	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	7	51	substitutions	substitution	NNS
cord-300883-rws11uel	7	52	(	(	-LRB-
cord-300883-rws11uel	7	53	d(N	d(N	NNP
cord-300883-rws11uel	7	54	)	)	-RRB-
cord-300883-rws11uel	7	55	)	)	-RRB-
cord-300883-rws11uel	7	56	than	than	IN
cord-300883-rws11uel	7	57	the	the	DT
cord-300883-rws11uel	7	58	synonymous	synonymous	JJ
cord-300883-rws11uel	7	59	substitutions	substitution	NNS
cord-300883-rws11uel	7	60	(	(	-LRB-
cord-300883-rws11uel	7	61	d(S	d(s	NN
cord-300883-rws11uel	7	62	)	)	-RRB-
cord-300883-rws11uel	7	63	)	)	-RRB-
cord-300883-rws11uel	7	64	with	with	IN
cord-300883-rws11uel	7	65	a	a	DT
cord-300883-rws11uel	7	66	posterior	posterior	JJ
cord-300883-rws11uel	7	67	probability	probability	NN
cord-300883-rws11uel	7	68	above	above	IN
cord-300883-rws11uel	7	69	0.95	0.95	CD
cord-300883-rws11uel	7	70	,	,	,
cord-300883-rws11uel	7	71	thus	thus	RB
cord-300883-rws11uel	7	72	suggesting	suggest	VBG
cord-300883-rws11uel	7	73	the	the	DT
cord-300883-rws11uel	7	74	evidence	evidence	NN
cord-300883-rws11uel	7	75	of	of	IN
cord-300883-rws11uel	7	76	adaptive	adaptive	JJ
cord-300883-rws11uel	7	77	evolution	evolution	NN
cord-300883-rws11uel	7	78	driven	drive	VBN
cord-300883-rws11uel	7	79	by	by	IN
cord-300883-rws11uel	7	80	Darwinian	darwinian	JJ
cord-300883-rws11uel	7	81	selection	selection	NN
cord-300883-rws11uel	7	82	.	.	.
cord-300883-rws11uel	8	1	Although	although	IN
cord-300883-rws11uel	8	2	it	-PRON-	PRP
cord-300883-rws11uel	8	3	is	be	VBZ
cord-300883-rws11uel	8	4	unclear	unclear	JJ
cord-300883-rws11uel	8	5	whether	whether	IN
cord-300883-rws11uel	8	6	these	these	DT
cord-300883-rws11uel	8	7	amino	amino	NN
cord-300883-rws11uel	8	8	acid	acid	JJ
cord-300883-rws11uel	8	9	adaptations	adaptation	NNS
cord-300883-rws11uel	8	10	are	be	VBP
cord-300883-rws11uel	8	11	driven	drive	VBN
cord-300883-rws11uel	8	12	by	by	IN
cord-300883-rws11uel	8	13	differential	differential	JJ
cord-300883-rws11uel	8	14	immune	immune	JJ
cord-300883-rws11uel	8	15	pressure	pressure	NN
cord-300883-rws11uel	8	16	or	or	CC
cord-300883-rws11uel	8	17	some	some	DT
cord-300883-rws11uel	8	18	other	other	JJ
cord-300883-rws11uel	8	19	factors	factor	NNS
cord-300883-rws11uel	8	20	,	,	,
cord-300883-rws11uel	8	21	identification	identification	NN
cord-300883-rws11uel	8	22	of	of	IN
cord-300883-rws11uel	8	23	these	these	DT
cord-300883-rws11uel	8	24	positively	positively	RB
cord-300883-rws11uel	8	25	selected	select	VBN
cord-300883-rws11uel	8	26	amino	amino	NN
cord-300883-rws11uel	8	27	acid	acid	NN
cord-300883-rws11uel	8	28	sites	site	NNS
cord-300883-rws11uel	8	29	would	would	MD
cord-300883-rws11uel	8	30	help	help	VB
cord-300883-rws11uel	8	31	in	in	IN
cord-300883-rws11uel	8	32	better	well	JJR
cord-300883-rws11uel	8	33	screening	screening	NN
cord-300883-rws11uel	8	34	using	use	VBG
cord-300883-rws11uel	8	35	epitope	epitope	NN
cord-300883-rws11uel	8	36	mapping	mapping	NN
cord-300883-rws11uel	8	37	technology	technology	NN
cord-300883-rws11uel	8	38	to	to	TO
cord-300883-rws11uel	8	39	identify	identify	VB
cord-300883-rws11uel	8	40	and	and	CC
cord-300883-rws11uel	8	41	localize	localize	VB
cord-300883-rws11uel	8	42	the	the	DT
cord-300883-rws11uel	8	43	sites	site	NNS
cord-300883-rws11uel	8	44	that	that	WDT
cord-300883-rws11uel	8	45	can	can	MD
cord-300883-rws11uel	8	46	be	be	VB
cord-300883-rws11uel	8	47	recognized	recognize	VBN
cord-300883-rws11uel	8	48	by	by	IN
cord-300883-rws11uel	8	49	the	the	DT
cord-300883-rws11uel	8	50	immune	immune	JJ
cord-300883-rws11uel	8	51	system	system	NN
cord-300883-rws11uel	8	52	.	.	.
cord-300883-rws11uel	9	1	We	-PRON-	PRP
cord-300883-rws11uel	9	2	also	also	RB
cord-300883-rws11uel	9	3	observed	observe	VBD
cord-300883-rws11uel	9	4	surprisingly	surprisingly	RB
cord-300883-rws11uel	9	5	higher	high	JJR
cord-300883-rws11uel	9	6	nucleotide	nucleotide	JJ
cord-300883-rws11uel	9	7	substitution	substitution	NN
cord-300883-rws11uel	9	8	rates	rate	NNS
cord-300883-rws11uel	9	9	per	per	IN
cord-300883-rws11uel	9	10	site	site	NN
cord-300883-rws11uel	9	11	,	,	,
cord-300883-rws11uel	9	12	per	per	IN
cord-300883-rws11uel	9	13	year	year	NN
cord-300883-rws11uel	9	14	for	for	IN
cord-300883-rws11uel	9	15	each	each	DT
cord-300883-rws11uel	9	16	lineage	lineage	NN
cord-300883-rws11uel	9	17	of	of	IN
cord-300883-rws11uel	10	1	hMPV	hMPV	NNP
cord-300883-rws11uel	10	2	than	than	IN
cord-300883-rws11uel	10	3	the	the	DT
cord-300883-rws11uel	10	4	rates	rate	NNS
cord-300883-rws11uel	10	5	that	that	WDT
cord-300883-rws11uel	10	6	were	be	VBD
cord-300883-rws11uel	10	7	previously	previously	RB
cord-300883-rws11uel	10	8	reported	report	VBN
cord-300883-rws11uel	10	9	for	for	IN
cord-300883-rws11uel	10	10	the	the	DT
cord-300883-rws11uel	10	11	human	human	JJ
cord-300883-rws11uel	10	12	respiratory	respiratory	JJ
cord-300883-rws11uel	10	13	syncytial	syncytial	JJ
cord-300883-rws11uel	10	14	virus	virus	NN
cord-300883-rws11uel	10	15	,	,	,
cord-300883-rws11uel	10	16	suggesting	suggest	VBG
cord-300883-rws11uel	10	17	rapid	rapid	JJ
cord-300883-rws11uel	10	18	evolutionary	evolutionary	JJ
cord-300883-rws11uel	10	19	dynamics	dynamic	NNS
cord-300883-rws11uel	10	20	of	of	IN
cord-300883-rws11uel	10	21	hMPV	hmpv	NN
cord-300883-rws11uel	10	22	.	.	.
cord-300883-rws11uel	11	1	Human	Human	NNP
cord-300883-rws11uel	11	2	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	11	3	(	(	-LRB-
cord-300883-rws11uel	11	4	hMPV	hmpv	NN
cord-300883-rws11uel	11	5	)	)	-RRB-
cord-300883-rws11uel	11	6	of	of	IN
cord-300883-rws11uel	11	7	the	the	DT
cord-300883-rws11uel	11	8	family	family	NN
cord-300883-rws11uel	11	9	Paramyxoviridae	Paramyxoviridae	NNP
cord-300883-rws11uel	11	10	and	and	CC
cord-300883-rws11uel	11	11	subfamily	subfamily	NN
cord-300883-rws11uel	11	12	Pneumoviridae	Pneumoviridae	NNP
cord-300883-rws11uel	11	13	was	be	VBD
cord-300883-rws11uel	11	14	first	first	RB
cord-300883-rws11uel	11	15	discovered	discover	VBN
cord-300883-rws11uel	11	16	in	in	IN
cord-300883-rws11uel	11	17	The	the	DT
cord-300883-rws11uel	11	18	Netherlands	Netherlands	NNP
cord-300883-rws11uel	11	19	from	from	IN
cord-300883-rws11uel	11	20	infants	infant	NNS
cord-300883-rws11uel	11	21	and	and	CC
cord-300883-rws11uel	11	22	children	child	NNS
cord-300883-rws11uel	11	23	suffering	suffer	VBG
cord-300883-rws11uel	11	24	from	from	IN
cord-300883-rws11uel	11	25	acute	acute	JJ
cord-300883-rws11uel	11	26	respiratory	respiratory	JJ
cord-300883-rws11uel	11	27	tract	tract	NN
cord-300883-rws11uel	11	28	disease	disease	NN
cord-300883-rws11uel	11	29	(	(	-LRB-
cord-300883-rws11uel	11	30	van	van	NNP
cord-300883-rws11uel	11	31	den	den	NNP
cord-300883-rws11uel	11	32	Hoogen	Hoogen	NNP
cord-300883-rws11uel	11	33	et	et	NNP
cord-300883-rws11uel	11	34	al	al	NNP
cord-300883-rws11uel	11	35	.	.	NNP
cord-300883-rws11uel	11	36	,	,	,
cord-300883-rws11uel	11	37	2001	2001	CD
cord-300883-rws11uel	11	38	)	)	-RRB-
cord-300883-rws11uel	11	39	.	.	.
cord-300883-rws11uel	12	1	Since	since	IN
cord-300883-rws11uel	12	2	then	then	RB
cord-300883-rws11uel	12	3	considerable	considerable	JJ
cord-300883-rws11uel	12	4	progress	progress	NN
cord-300883-rws11uel	12	5	has	have	VBZ
cord-300883-rws11uel	12	6	been	be	VBN
cord-300883-rws11uel	12	7	made	make	VBN
cord-300883-rws11uel	12	8	in	in	IN
cord-300883-rws11uel	12	9	identification	identification	NN
cord-300883-rws11uel	12	10	and	and	CC
cord-300883-rws11uel	12	11	characterization	characterization	NN
cord-300883-rws11uel	12	12	(	(	-LRB-
cord-300883-rws11uel	12	13	Cote	Cote	NNP
cord-300883-rws11uel	12	14	et	et	FW
cord-300883-rws11uel	12	15	al	al	NNP
cord-300883-rws11uel	12	16	.	.	.
cord-300883-rws11uel	13	1	,	,	,
cord-300883-rws11uel	13	2	2003	2003	CD
cord-300883-rws11uel	13	3	;	;	:
cord-300883-rws11uel	13	4	Mackay	Mackay	NNP
cord-300883-rws11uel	13	5	et	et	NNP
cord-300883-rws11uel	13	6	al	al	NNP
cord-300883-rws11uel	13	7	.	.	NNP
cord-300883-rws11uel	13	8	,	,	,
cord-300883-rws11uel	13	9	2003	2003	CD
cord-300883-rws11uel	13	10	;	;	:
cord-300883-rws11uel	13	11	Ebihara	Ebihara	NNP
cord-300883-rws11uel	13	12	et	et	NNP
cord-300883-rws11uel	13	13	al	al	NNP
cord-300883-rws11uel	13	14	.	.	NNP
cord-300883-rws11uel	13	15	,	,	,
cord-300883-rws11uel	13	16	2004	2004	CD
cord-300883-rws11uel	14	1	;	;	:
cord-300883-rws11uel	14	2	Maertzdorf	Maertzdorf	NNP
cord-300883-rws11uel	14	3	et	et	NNP
cord-300883-rws11uel	14	4	al	al	NNP
cord-300883-rws11uel	14	5	.	.	NNP
cord-300883-rws11uel	14	6	,	,	,
cord-300883-rws11uel	14	7	2004	2004	CD
cord-300883-rws11uel	14	8	;	;	:
cord-300883-rws11uel	14	9	Skiadopoulos	Skiadopoulos	NNP
cord-300883-rws11uel	14	10	et	et	NNP
cord-300883-rws11uel	14	11	al	al	NNP
cord-300883-rws11uel	14	12	.	.	NNP
cord-300883-rws11uel	14	13	,	,	,
cord-300883-rws11uel	14	14	2004	2004	CD
cord-300883-rws11uel	14	15	;	;	:
cord-300883-rws11uel	14	16	Hamelin	Hamelin	NNP
cord-300883-rws11uel	14	17	and	and	CC
cord-300883-rws11uel	14	18	Boivin	Boivin	NNP
cord-300883-rws11uel	14	19	,	,	,
cord-300883-rws11uel	14	20	2005	2005	CD
cord-300883-rws11uel	14	21	;	;	:
cord-300883-rws11uel	14	22	Leung	Leung	NNP
cord-300883-rws11uel	14	23	et	et	NNP
cord-300883-rws11uel	14	24	al	al	NNP
cord-300883-rws11uel	14	25	.	.	NNP
cord-300883-rws11uel	14	26	,	,	,
cord-300883-rws11uel	14	27	2005	2005	CD
cord-300883-rws11uel	14	28	;	;	:
cord-300883-rws11uel	14	29	Gray	Gray	NNP
cord-300883-rws11uel	14	30	et	et	NNP
cord-300883-rws11uel	14	31	al	al	NNP
cord-300883-rws11uel	14	32	.	.	NNP
cord-300883-rws11uel	14	33	,	,	,
cord-300883-rws11uel	14	34	2006a	2006a	CD
cord-300883-rws11uel	14	35	,	,	,
cord-300883-rws11uel	14	36	b	b	LS
cord-300883-rws11uel	14	37	;	;	:
cord-300883-rws11uel	14	38	Ulbrand	Ulbrand	NNP
cord-300883-rws11uel	14	39	et	et	NNP
cord-300883-rws11uel	14	40	al	al	NNP
cord-300883-rws11uel	14	41	.	.	NNP
cord-300883-rws11uel	14	42	,	,	,
cord-300883-rws11uel	14	43	2006	2006	CD
cord-300883-rws11uel	14	44	;	;	:
cord-300883-rws11uel	14	45	van	van	NNP
cord-300883-rws11uel	14	46	den	den	NNP
cord-300883-rws11uel	14	47	Hoogen	Hoogen	NNP
cord-300883-rws11uel	14	48	,	,	,
cord-300883-rws11uel	14	49	2007	2007	CD
cord-300883-rws11uel	14	50	)	)	-RRB-
cord-300883-rws11uel	14	51	as	as	RB
cord-300883-rws11uel	14	52	well	well	RB
cord-300883-rws11uel	14	53	as	as	IN
cord-300883-rws11uel	15	1	in	in	IN
cord-300883-rws11uel	15	2	understanding	understand	VBG
cord-300883-rws11uel	15	3	its	-PRON-	PRP$
cord-300883-rws11uel	15	4	genetic	genetic	JJ
cord-300883-rws11uel	15	5	diversity	diversity	NN
cord-300883-rws11uel	15	6	(	(	-LRB-
cord-300883-rws11uel	15	7	Bastien	Bastien	NNP
cord-300883-rws11uel	15	8	et	et	NNP
cord-300883-rws11uel	15	9	al	al	NNP
cord-300883-rws11uel	15	10	.	.	.
cord-300883-rws11uel	16	1	,	,	,
cord-300883-rws11uel	16	2	2003	2003	CD
cord-300883-rws11uel	17	1	(	(	-LRB-
cord-300883-rws11uel	17	2	Bastien	Bastien	NNP
cord-300883-rws11uel	17	3	et	et	NNP
cord-300883-rws11uel	17	4	al	al	NNP
cord-300883-rws11uel	17	5	.	.	.
cord-300883-rws11uel	18	1	,	,	,
cord-300883-rws11uel	18	2	,	,	,
cord-300883-rws11uel	18	3	2004	2004	CD
cord-300883-rws11uel	18	4	Biacchesi	Biacchesi	NNP
cord-300883-rws11uel	18	5	et	et	NNP
cord-300883-rws11uel	18	6	al	al	NNP
cord-300883-rws11uel	18	7	.	.	NNP
cord-300883-rws11uel	18	8	,	,	,
cord-300883-rws11uel	18	9	2003	2003	CD
cord-300883-rws11uel	19	1	;	;	:
cord-300883-rws11uel	19	2	Ishiguro	Ishiguro	NNP
cord-300883-rws11uel	19	3	et	et	NNP
cord-300883-rws11uel	19	4	al	al	NNP
cord-300883-rws11uel	19	5	.	.	NNP
cord-300883-rws11uel	19	6	,	,	,
cord-300883-rws11uel	19	7	2004	2004	CD
cord-300883-rws11uel	19	8	;	;	:
cord-300883-rws11uel	19	9	Peret	Peret	NNP
cord-300883-rws11uel	19	10	et	et	NNP
cord-300883-rws11uel	19	11	al	al	NNP
cord-300883-rws11uel	19	12	.	.	NNP
cord-300883-rws11uel	19	13	,	,	,
cord-300883-rws11uel	19	14	2004	2004	CD
cord-300883-rws11uel	20	1	;	;	:
cord-300883-rws11uel	20	2	Carr	Carr	NNP
cord-300883-rws11uel	20	3	et	et	NNP
cord-300883-rws11uel	20	4	al	al	NNP
cord-300883-rws11uel	20	5	.	.	.
cord-300883-rws11uel	21	1	,	,	,
cord-300883-rws11uel	21	2	2005	2005	CD
cord-300883-rws11uel	21	3	;	;	:
cord-300883-rws11uel	21	4	Ludewick	Ludewick	NNP
cord-300883-rws11uel	21	5	et	et	NNP
cord-300883-rws11uel	21	6	al	al	NNP
cord-300883-rws11uel	21	7	.	.	.
cord-300883-rws11uel	22	1	,	,	,
cord-300883-rws11uel	22	2	2005	2005	CD
cord-300883-rws11uel	22	3	;	;	:
cord-300883-rws11uel	22	4	Galiano	Galiano	NNP
cord-300883-rws11uel	22	5	et	et	NNP
cord-300883-rws11uel	22	6	al	al	NNP
cord-300883-rws11uel	22	7	.	.	NNP
cord-300883-rws11uel	22	8	,	,	,
cord-300883-rws11uel	22	9	2006	2006	CD
cord-300883-rws11uel	22	10	;	;	:
cord-300883-rws11uel	22	11	Boivin	Boivin	NNP
cord-300883-rws11uel	22	12	et	et	NNP
cord-300883-rws11uel	22	13	al	al	NNP
cord-300883-rws11uel	22	14	.	.	NNP
cord-300883-rws11uel	22	15	,	,	,
cord-300883-rws11uel	22	16	2007	2007	CD
cord-300883-rws11uel	22	17	)	)	-RRB-
cord-300883-rws11uel	22	18	.	.	.
cord-300883-rws11uel	23	1	To	to	IN
cord-300883-rws11uel	23	2	date	date	NN
cord-300883-rws11uel	23	3	this	this	DT
cord-300883-rws11uel	23	4	virus	virus	NN
cord-300883-rws11uel	23	5	has	have	VBZ
cord-300883-rws11uel	23	6	been	be	VBN
cord-300883-rws11uel	23	7	identified	identify	VBN
cord-300883-rws11uel	23	8	in	in	IN
cord-300883-rws11uel	23	9	many	many	JJ
cord-300883-rws11uel	23	10	countries	country	NNS
cord-300883-rws11uel	23	11	from	from	IN
cord-300883-rws11uel	23	12	different	different	JJ
cord-300883-rws11uel	23	13	age	age	NN
cord-300883-rws11uel	23	14	groups	group	NNS
cord-300883-rws11uel	23	15	and	and	CC
cord-300883-rws11uel	23	16	reported	report	VBD
cord-300883-rws11uel	23	17	to	to	TO
cord-300883-rws11uel	23	18	cause	cause	VB
cord-300883-rws11uel	23	19	upper	upper	JJ
cord-300883-rws11uel	23	20	respiratory	respiratory	JJ
cord-300883-rws11uel	23	21	tract	tract	NN
cord-300883-rws11uel	23	22	infections	infection	NNS
cord-300883-rws11uel	23	23	,	,	,
cord-300883-rws11uel	23	24	flu	flu	NN
cord-300883-rws11uel	23	25	-	-	HYPH
cord-300883-rws11uel	23	26	like	like	JJ
cord-300883-rws11uel	23	27	infections	infection	NNS
cord-300883-rws11uel	23	28	,	,	,
cord-300883-rws11uel	23	29	and	and	CC
cord-300883-rws11uel	23	30	has	have	VBZ
cord-300883-rws11uel	23	31	also	also	RB
cord-300883-rws11uel	23	32	been	be	VBN
cord-300883-rws11uel	23	33	associated	associate	VBN
cord-300883-rws11uel	23	34	with	with	IN
cord-300883-rws11uel	23	35	lower	low	JJR
cord-300883-rws11uel	23	36	respiratory	respiratory	JJ
cord-300883-rws11uel	23	37	tract	tract	NN
cord-300883-rws11uel	23	38	infections	infection	NNS
cord-300883-rws11uel	23	39	*	*	NFP
cord-300883-rws11uel	23	40	Corresponding	correspond	VBG
cord-300883-rws11uel	23	41	author	author	NN
cord-300883-rws11uel	23	42	.	.	.
cord-300883-rws11uel	24	1	Tel	Tel	NNP
cord-300883-rws11uel	24	2	.	.	.
cord-300883-rws11uel	25	1	:	:	:
cord-300883-rws11uel	25	2	+1	+1	NFP
cord-300883-rws11uel	25	3	918	918	CD
cord-300883-rws11uel	25	4	631	631	CD
cord-300883-rws11uel	25	5	3062	3062	CD
cord-300883-rws11uel	26	1	;	;	:
cord-300883-rws11uel	26	2	fax	fax	NN
cord-300883-rws11uel	26	3	:	:	:
cord-300883-rws11uel	26	4	+1	+1	NFP
cord-300883-rws11uel	26	5	918	918	CD
cord-300883-rws11uel	26	6	631	631	CD
cord-300883-rws11uel	26	7	2762	2762	CD
cord-300883-rws11uel	26	8	.	.	.
cord-300883-rws11uel	27	1	E	e	NN
cord-300883-rws11uel	27	2	-	-	NN
cord-300883-rws11uel	27	3	mail	mail	NN
cord-300883-rws11uel	27	4	address	address	NN
cord-300883-rws11uel	27	5	:	:	:
cord-300883-rws11uel	27	6	abinash-padhi@utulsa.edu	abinash-padhi@utulsa.edu	NNP
cord-300883-rws11uel	27	7	(	(	-LRB-
cord-300883-rws11uel	27	8	A.	A.	NNP
cord-300883-rws11uel	27	9	Padhi	Padhi	NNP
cord-300883-rws11uel	27	10	)	)	-RRB-
cord-300883-rws11uel	27	11	.	.	.
cord-300883-rws11uel	28	1	(	(	-LRB-
cord-300883-rws11uel	28	2	van	van	NNP
cord-300883-rws11uel	28	3	den	den	NNP
cord-300883-rws11uel	28	4	Hoogen	Hoogen	NNP
cord-300883-rws11uel	28	5	et	et	NNP
cord-300883-rws11uel	28	6	al	al	NNP
cord-300883-rws11uel	28	7	.	.	NNP
cord-300883-rws11uel	28	8	,	,	,
cord-300883-rws11uel	28	9	2001	2001	CD
cord-300883-rws11uel	29	1	;	;	:
cord-300883-rws11uel	29	2	Stockton	Stockton	NNP
cord-300883-rws11uel	29	3	et	et	NNP
cord-300883-rws11uel	29	4	al	al	NNP
cord-300883-rws11uel	29	5	.	.	NNP
cord-300883-rws11uel	29	6	,	,	,
cord-300883-rws11uel	29	7	2002	2002	CD
cord-300883-rws11uel	29	8	;	;	:
cord-300883-rws11uel	29	9	Biacchesi	Biacchesi	NNP
cord-300883-rws11uel	29	10	et	et	NNP
cord-300883-rws11uel	29	11	al	al	NNP
cord-300883-rws11uel	29	12	.	.	NNP
cord-300883-rws11uel	29	13	,	,	,
cord-300883-rws11uel	29	14	2003	2003	CD
cord-300883-rws11uel	30	1	;	;	:
cord-300883-rws11uel	30	2	Bastien	Bastien	NNP
cord-300883-rws11uel	30	3	et	et	NNP
cord-300883-rws11uel	30	4	al	al	NNP
cord-300883-rws11uel	30	5	.	.	NNP
cord-300883-rws11uel	30	6	,	,	,
cord-300883-rws11uel	30	7	2003	2003	CD
cord-300883-rws11uel	31	1	Bastien	Bastien	NNP
cord-300883-rws11uel	31	2	et	et	NNP
cord-300883-rws11uel	31	3	al	al	NNP
cord-300883-rws11uel	31	4	.	.	.
cord-300883-rws11uel	32	1	,	,	,
cord-300883-rws11uel	32	2	,	,	,
cord-300883-rws11uel	32	3	2004	2004	CD
cord-300883-rws11uel	32	4	Ishiguro	Ishiguro	NNP
cord-300883-rws11uel	32	5	et	et	NNP
cord-300883-rws11uel	32	6	al	al	NNP
cord-300883-rws11uel	32	7	.	.	NNP
cord-300883-rws11uel	32	8	,	,	,
cord-300883-rws11uel	32	9	2004	2004	CD
cord-300883-rws11uel	32	10	;	;	:
cord-300883-rws11uel	32	11	Peret	Peret	NNP
cord-300883-rws11uel	32	12	et	et	NNP
cord-300883-rws11uel	32	13	al	al	NNP
cord-300883-rws11uel	32	14	.	.	NNP
cord-300883-rws11uel	32	15	,	,	,
cord-300883-rws11uel	32	16	2004	2004	CD
cord-300883-rws11uel	33	1	;	;	:
cord-300883-rws11uel	33	2	Carr	Carr	NNP
cord-300883-rws11uel	33	3	et	et	NNP
cord-300883-rws11uel	33	4	al	al	NNP
cord-300883-rws11uel	33	5	.	.	.
cord-300883-rws11uel	34	1	,	,	,
cord-300883-rws11uel	34	2	2005	2005	CD
cord-300883-rws11uel	34	3	;	;	:
cord-300883-rws11uel	34	4	Ludewick	Ludewick	NNP
cord-300883-rws11uel	34	5	et	et	NNP
cord-300883-rws11uel	34	6	al	al	NNP
cord-300883-rws11uel	34	7	.	.	.
cord-300883-rws11uel	35	1	,	,	,
cord-300883-rws11uel	35	2	2005	2005	CD
cord-300883-rws11uel	35	3	;	;	:
cord-300883-rws11uel	35	4	Fouchier	Fouchier	NNP
cord-300883-rws11uel	35	5	et	et	NNP
cord-300883-rws11uel	35	6	al	al	NNP
cord-300883-rws11uel	35	7	.	.	.
cord-300883-rws11uel	36	1	,	,	,
cord-300883-rws11uel	36	2	2005	2005	CD
cord-300883-rws11uel	36	3	;	;	:
cord-300883-rws11uel	36	4	Regev	Regev	NNP
cord-300883-rws11uel	36	5	et	et	NNP
cord-300883-rws11uel	36	6	al	al	NNP
cord-300883-rws11uel	36	7	.	.	NNP
cord-300883-rws11uel	36	8	,	,	,
cord-300883-rws11uel	36	9	2006	2006	CD
cord-300883-rws11uel	37	1	;	;	:
cord-300883-rws11uel	37	2	Galiano	Galiano	NNP
cord-300883-rws11uel	37	3	et	et	NNP
cord-300883-rws11uel	37	4	al	al	NNP
cord-300883-rws11uel	37	5	.	.	NNP
cord-300883-rws11uel	37	6	,	,	,
cord-300883-rws11uel	37	7	2006	2006	CD
cord-300883-rws11uel	37	8	;	;	:
cord-300883-rws11uel	37	9	Kahn	Kahn	NNP
cord-300883-rws11uel	37	10	,	,	,
cord-300883-rws11uel	37	11	2006	2006	CD
cord-300883-rws11uel	37	12	;	;	:
cord-300883-rws11uel	37	13	Gray	Gray	NNP
cord-300883-rws11uel	37	14	et	et	NNP
cord-300883-rws11uel	37	15	al	al	NNP
cord-300883-rws11uel	37	16	.	.	.
cord-300883-rws11uel	38	1	,	,	,
cord-300883-rws11uel	38	2	2006a	2006a	CD
cord-300883-rws11uel	38	3	,	,	,
cord-300883-rws11uel	38	4	b	b	LS
cord-300883-rws11uel	38	5	)	)	-RRB-
cord-300883-rws11uel	38	6	,	,	,
cord-300883-rws11uel	38	7	a	a	DT
cord-300883-rws11uel	38	8	pattern	pattern	NN
cord-300883-rws11uel	38	9	similar	similar	JJ
cord-300883-rws11uel	38	10	to	to	IN
cord-300883-rws11uel	38	11	that	that	DT
cord-300883-rws11uel	38	12	reported	report	VBN
cord-300883-rws11uel	38	13	for	for	IN
cord-300883-rws11uel	38	14	human	human	JJ
cord-300883-rws11uel	38	15	respiratory	respiratory	JJ
cord-300883-rws11uel	38	16	syncytial	syncytial	JJ
cord-300883-rws11uel	38	17	virus	virus	NN
cord-300883-rws11uel	38	18	(	(	-LRB-
cord-300883-rws11uel	38	19	HRSV	HRSV	NNP
cord-300883-rws11uel	38	20	)	)	-RRB-
cord-300883-rws11uel	38	21	.	.	.
cord-300883-rws11uel	39	1	Although	although	IN
cord-300883-rws11uel	39	2	comparative	comparative	JJ
cord-300883-rws11uel	39	3	genome	genome	NN
cord-300883-rws11uel	39	4	mapping	mapping	NN
cord-300883-rws11uel	39	5	analyses	analysis	NNS
cord-300883-rws11uel	39	6	suggested	suggest	VBD
cord-300883-rws11uel	39	7	that	that	IN
cord-300883-rws11uel	39	8	this	this	DT
cord-300883-rws11uel	39	9	virus	virus	NN
cord-300883-rws11uel	39	10	has	have	VBZ
cord-300883-rws11uel	39	11	structural	structural	JJ
cord-300883-rws11uel	39	12	and	and	CC
cord-300883-rws11uel	39	13	functional	functional	JJ
cord-300883-rws11uel	39	14	similarities	similarity	NNS
cord-300883-rws11uel	39	15	with	with	IN
cord-300883-rws11uel	39	16	HRSV	HRSV	NNP
cord-300883-rws11uel	39	17	(	(	-LRB-
cord-300883-rws11uel	39	18	Kahn	Kahn	NNP
cord-300883-rws11uel	39	19	,	,	,
cord-300883-rws11uel	39	20	2006	2006	CD
cord-300883-rws11uel	39	21	)	)	-RRB-
cord-300883-rws11uel	39	22	,	,	,
cord-300883-rws11uel	39	23	recent	recent	JJ
cord-300883-rws11uel	39	24	studies	study	NNS
cord-300883-rws11uel	39	25	reported	report	VBD
cord-300883-rws11uel	39	26	that	that	IN
cord-300883-rws11uel	39	27	the	the	DT
cord-300883-rws11uel	39	28	attachment	attachment	NN
cord-300883-rws11uel	39	29	(	(	-LRB-
cord-300883-rws11uel	39	30	G	g	NN
cord-300883-rws11uel	39	31	)	)	-RRB-
cord-300883-rws11uel	39	32	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	39	33	of	of	IN
cord-300883-rws11uel	39	34	these	these	DT
cord-300883-rws11uel	39	35	paramimyxoviruses	paramimyxoviruse	NNS
cord-300883-rws11uel	39	36	exhibit	exhibit	VBP
cord-300883-rws11uel	39	37	extensive	extensive	JJ
cord-300883-rws11uel	39	38	nucleotide	nucleotide	NN
cord-300883-rws11uel	39	39	and	and	CC
cord-300883-rws11uel	39	40	amino	amino	NN
cord-300883-rws11uel	39	41	acid	acid	NN
cord-300883-rws11uel	39	42	variation	variation	NN
cord-300883-rws11uel	39	43	,	,	,
cord-300883-rws11uel	39	44	with	with	IN
cord-300883-rws11uel	39	45	most	most	JJS
cord-300883-rws11uel	39	46	differences	difference	NNS
cord-300883-rws11uel	39	47	located	locate	VBN
cord-300883-rws11uel	39	48	in	in	IN
cord-300883-rws11uel	39	49	the	the	DT
cord-300883-rws11uel	39	50	extracellular	extracellular	JJ
cord-300883-rws11uel	39	51	domain	domain	NN
cord-300883-rws11uel	39	52	(	(	-LRB-
cord-300883-rws11uel	39	53	Peret	Peret	NNP
cord-300883-rws11uel	39	54	et	et	NNP
cord-300883-rws11uel	39	55	al	al	NNP
cord-300883-rws11uel	39	56	.	.	NNP
cord-300883-rws11uel	39	57	,	,	,
cord-300883-rws11uel	39	58	2004	2004	CD
cord-300883-rws11uel	39	59	;	;	:
cord-300883-rws11uel	39	60	Kahn	Kahn	NNP
cord-300883-rws11uel	39	61	,	,	,
cord-300883-rws11uel	39	62	2006	2006	CD
cord-300883-rws11uel	39	63	)	)	-RRB-
cord-300883-rws11uel	39	64	.	.	.
cord-300883-rws11uel	40	1	Therefore	therefore	RB
cord-300883-rws11uel	40	2	,	,	,
cord-300883-rws11uel	40	3	G	g	NN
cord-300883-rws11uel	40	4	-	-	HYPH
cord-300883-rws11uel	40	5	protein	protein	NN
cord-300883-rws11uel	40	6	has	have	VBZ
cord-300883-rws11uel	40	7	been	be	VBN
cord-300883-rws11uel	40	8	widely	widely	RB
cord-300883-rws11uel	40	9	used	use	VBN
cord-300883-rws11uel	40	10	to	to	TO
cord-300883-rws11uel	40	11	infer	infer	VB
cord-300883-rws11uel	40	12	evolutionary	evolutionary	JJ
cord-300883-rws11uel	40	13	relationships	relationship	NNS
cord-300883-rws11uel	40	14	among	among	IN
cord-300883-rws11uel	40	15	the	the	DT
cord-300883-rws11uel	40	16	isolates	isolate	NNS
cord-300883-rws11uel	40	17	from	from	IN
cord-300883-rws11uel	40	18	different	different	JJ
cord-300883-rws11uel	40	19	geographic	geographic	JJ
cord-300883-rws11uel	40	20	regions	region	NNS
cord-300883-rws11uel	40	21	(	(	-LRB-
cord-300883-rws11uel	40	22	e.g.	e.g.	RB
cord-300883-rws11uel	40	23	,	,	,
cord-300883-rws11uel	40	24	Peret	Peret	NNP
cord-300883-rws11uel	40	25	et	et	NNP
cord-300883-rws11uel	40	26	al	al	NNP
cord-300883-rws11uel	40	27	.	.	NNP
cord-300883-rws11uel	40	28	,	,	,
cord-300883-rws11uel	40	29	2004	2004	CD
cord-300883-rws11uel	40	30	;	;	:
cord-300883-rws11uel	40	31	Ishiguro	Ishiguro	NNP
cord-300883-rws11uel	40	32	et	et	NNP
cord-300883-rws11uel	40	33	al	al	NNP
cord-300883-rws11uel	40	34	.	.	NNP
cord-300883-rws11uel	40	35	,	,	,
cord-300883-rws11uel	40	36	2004	2004	CD
cord-300883-rws11uel	40	37	)	)	-RRB-
cord-300883-rws11uel	40	38	.	.	.
cord-300883-rws11uel	41	1	Although	although	IN
cord-300883-rws11uel	41	2	phylogenetic	phylogenetic	JJ
cord-300883-rws11uel	41	3	analyses	analysis	NNS
cord-300883-rws11uel	41	4	of	of	IN
cord-300883-rws11uel	41	5	hMPVs	hmpvs	CD
cord-300883-rws11uel	41	6	from	from	IN
cord-300883-rws11uel	41	7	the	the	DT
cord-300883-rws11uel	41	8	complete	complete	JJ
cord-300883-rws11uel	41	9	nucleotide	nucleotide	JJ
cord-300883-rws11uel	41	10	coding	coding	NN
cord-300883-rws11uel	41	11	sequences	sequence	NNS
cord-300883-rws11uel	41	12	revealed	reveal	VBD
cord-300883-rws11uel	41	13	the	the	DT
cord-300883-rws11uel	41	14	existence	existence	NN
cord-300883-rws11uel	41	15	of	of	IN
cord-300883-rws11uel	41	16	two	two	CD
cord-300883-rws11uel	41	17	major	major	JJ
cord-300883-rws11uel	41	18	lineages	lineage	NNS
cord-300883-rws11uel	41	19	of	of	IN
cord-300883-rws11uel	41	20	hMPVs	hmpvs	CD
cord-300883-rws11uel	41	21	,	,	,
cord-300883-rws11uel	41	22	recent	recent	JJ
cord-300883-rws11uel	41	23	analyses	analysis	NNS
cord-300883-rws11uel	41	24	based	base	VBN
cord-300883-rws11uel	41	25	on	on	IN
cord-300883-rws11uel	41	26	G	g	NN
cord-300883-rws11uel	41	27	-	-	HYPH
cord-300883-rws11uel	41	28	protein	protein	NN
cord-300883-rws11uel	41	29	phylogeny	phylogeny	NN
cord-300883-rws11uel	41	30	revealed	reveal	VBD
cord-300883-rws11uel	41	31	the	the	DT
cord-300883-rws11uel	41	32	existence	existence	NN
cord-300883-rws11uel	41	33	of	of	IN
cord-300883-rws11uel	41	34	two	two	CD
cord-300883-rws11uel	41	35	minor	minor	JJ
cord-300883-rws11uel	41	36	subgroups	subgroup	NNS
cord-300883-rws11uel	41	37	within	within	IN
cord-300883-rws11uel	41	38	each	each	DT
cord-300883-rws11uel	41	39	major	major	JJ
cord-300883-rws11uel	41	40	lineage	lineage	NN
cord-300883-rws11uel	41	41	(	(	-LRB-
cord-300883-rws11uel	41	42	Peret	Peret	NNP
cord-300883-rws11uel	41	43	et	et	NNP
cord-300883-rws11uel	41	44	al	al	NNP
cord-300883-rws11uel	41	45	.	.	NNP
cord-300883-rws11uel	41	46	,	,	,
cord-300883-rws11uel	41	47	2004	2004	CD
cord-300883-rws11uel	41	48	)	)	-RRB-
cord-300883-rws11uel	41	49	.	.	.
cord-300883-rws11uel	42	1	Despite	despite	IN
cord-300883-rws11uel	42	2	the	the	DT
cord-300883-rws11uel	42	3	knowledge	knowledge	NN
cord-300883-rws11uel	42	4	of	of	IN
cord-300883-rws11uel	42	5	identification	identification	NN
cord-300883-rws11uel	42	6	and	and	CC
cord-300883-rws11uel	42	7	characterization	characterization	NN
cord-300883-rws11uel	42	8	of	of	IN
cord-300883-rws11uel	42	9	hMPVs	hmpvs	CD
cord-300883-rws11uel	42	10	,	,	,
cord-300883-rws11uel	42	11	the	the	DT
cord-300883-rws11uel	42	12	possible	possible	JJ
cord-300883-rws11uel	42	13	mechanism	mechanism	NN
cord-300883-rws11uel	42	14	by	by	IN
cord-300883-rws11uel	42	15	which	which	WDT
cord-300883-rws11uel	42	16	hMPV	hmpv	NN
cord-300883-rws11uel	42	17	G	g	NN
cord-300883-rws11uel	42	18	-	-	HYPH
cord-300883-rws11uel	42	19	proteins	protein	NNS
cord-300883-rws11uel	42	20	have	have	VBP
cord-300883-rws11uel	42	21	evolved	evolve	VBN
cord-300883-rws11uel	42	22	is	be	VBZ
cord-300883-rws11uel	42	23	poorly	poorly	RB
cord-300883-rws11uel	42	24	understood	understand	VBN
cord-300883-rws11uel	42	25	.	.	.
cord-300883-rws11uel	43	1	Earlier	early	JJR
cord-300883-rws11uel	43	2	studies	study	NNS
cord-300883-rws11uel	43	3	on	on	IN
cord-300883-rws11uel	43	4	the	the	DT
cord-300883-rws11uel	43	5	molecular	molecular	JJ
cord-300883-rws11uel	43	6	evolution	evolution	NN
cord-300883-rws11uel	43	7	of	of	IN
cord-300883-rws11uel	43	8	HRSV	HRSV	NNP
cord-300883-rws11uel	43	9	Gprotein	Gprotein	NNP
cord-300883-rws11uel	43	10	reported	report	VBD
cord-300883-rws11uel	43	11	that	that	IN
cord-300883-rws11uel	43	12	certain	certain	JJ
cord-300883-rws11uel	43	13	amino	amino	NN
cord-300883-rws11uel	43	14	acid	acid	NN
cord-300883-rws11uel	43	15	sites	site	NNS
cord-300883-rws11uel	43	16	that	that	WDT
cord-300883-rws11uel	43	17	correspond	correspond	VBP
cord-300883-rws11uel	43	18	to	to	IN
cord-300883-rws11uel	43	19	sites	site	NNS
cord-300883-rws11uel	43	20	of	of	IN
cord-300883-rws11uel	43	21	O	o	NN
cord-300883-rws11uel	43	22	-	-	HYPH
cord-300883-rws11uel	43	23	glycosylation	glycosylation	NN
cord-300883-rws11uel	43	24	,	,	,
cord-300883-rws11uel	43	25	or	or	CC
cord-300883-rws11uel	43	26	amino	amino	NN
cord-300883-rws11uel	43	27	acid	acid	NN
cord-300883-rws11uel	43	28	sites	site	NNS
cord-300883-rws11uel	43	29	that	that	WDT
cord-300883-rws11uel	43	30	were	be	VBD
cord-300883-rws11uel	43	31	previously	previously	RB
cord-300883-rws11uel	43	32	described	describe	VBN
cord-300883-rws11uel	43	33	as	as	IN
cord-300883-rws11uel	43	34	monoclonal	monoclonal	JJ
cord-300883-rws11uel	43	35	antibody	antibody	NN
cord-300883-rws11uel	43	36	-	-	HYPH
cord-300883-rws11uel	43	37	induced	induce	VBN
cord-300883-rws11uel	43	38	in	in	IN
cord-300883-rws11uel	43	39	vitro	vitro	FW
cord-300883-rws11uel	43	40	escape	escape	NN
cord-300883-rws11uel	43	41	mutants	mutant	NNS
cord-300883-rws11uel	43	42	,	,	,
cord-300883-rws11uel	43	43	are	be	VBP
cord-300883-rws11uel	43	44	under	under	IN
cord-300883-rws11uel	43	45	positive	positive	JJ
cord-300883-rws11uel	43	46	selection	selection	NN
cord-300883-rws11uel	43	47	and	and	CC
cord-300883-rws11uel	43	48	thus	thus	RB
cord-300883-rws11uel	43	49	showed	show	VBD
cord-300883-rws11uel	43	50	strong	strong	JJ
cord-300883-rws11uel	43	51	association	association	NN
cord-300883-rws11uel	43	52	between	between	IN
cord-300883-rws11uel	43	53	these	these	DT
cord-300883-rws11uel	43	54	positively	positively	RB
cord-300883-rws11uel	43	55	selected	select	VBN
cord-300883-rws11uel	43	56	sites	site	NNS
cord-300883-rws11uel	43	57	and	and	CC
cord-300883-rws11uel	43	58	the	the	DT
cord-300883-rws11uel	43	59	mapped	map	VBN
cord-300883-rws11uel	43	60	neutralizing	neutralize	VBG
cord-300883-rws11uel	43	61	epitopes	epitope	NNS
cord-300883-rws11uel	43	62	(	(	-LRB-
cord-300883-rws11uel	43	63	Zlateva	Zlateva	NNP
cord-300883-rws11uel	43	64	et	et	FW
cord-300883-rws11uel	43	65	al	al	NNP
cord-300883-rws11uel	43	66	.	.	NNP
cord-300883-rws11uel	43	67	,	,	,
cord-300883-rws11uel	43	68	2004	2004	CD
cord-300883-rws11uel	43	69	)	)	-RRB-
cord-300883-rws11uel	43	70	.	.	.
cord-300883-rws11uel	44	1	Recently	recently	RB
cord-300883-rws11uel	44	2	,	,	,
cord-300883-rws11uel	44	3	Zhang	Zhang	NNP
cord-300883-rws11uel	44	4	et	et	NNP
cord-300883-rws11uel	44	5	al	al	NNP
cord-300883-rws11uel	44	6	.	.	.
cord-300883-rws11uel	45	1	(	(	-LRB-
cord-300883-rws11uel	45	2	2006	2006	CD
cord-300883-rws11uel	45	3	)	)	-RRB-
cord-300883-rws11uel	45	4	also	also	RB
cord-300883-rws11uel	45	5	reported	report	VBD
cord-300883-rws11uel	45	6	that	that	IN
cord-300883-rws11uel	45	7	certain	certain	JJ
cord-300883-rws11uel	45	8	amino	amino	NN
cord-300883-rws11uel	45	9	acid	acid	NN
cord-300883-rws11uel	45	10	sites	site	NNS
cord-300883-rws11uel	45	11	in	in	IN
cord-300883-rws11uel	45	12	severe	severe	JJ
cord-300883-rws11uel	45	13	acute	acute	JJ
cord-300883-rws11uel	45	14	respiratory	respiratory	JJ
cord-300883-rws11uel	45	15	syndrome	syndrome	NN
cord-300883-rws11uel	45	16	(	(	-LRB-
cord-300883-rws11uel	45	17	SARS	SARS	NNP
cord-300883-rws11uel	45	18	)	)	-RRB-
cord-300883-rws11uel	45	19	coronavirus	coronavirus	NN
cord-300883-rws11uel	45	20	(	(	-LRB-
cord-300883-rws11uel	45	21	CoV	CoV	NNP
cord-300883-rws11uel	45	22	)	)	-RRB-
cord-300883-rws11uel	45	23	are	be	VBP
cord-300883-rws11uel	45	24	evolved	evolve	VBN
cord-300883-rws11uel	45	25	by	by	IN
cord-300883-rws11uel	45	26	positive	positive	JJ
cord-300883-rws11uel	45	27	Darwinian	darwinian	JJ
cord-300883-rws11uel	45	28	selection	selection	NN
cord-300883-rws11uel	45	29	.	.	.
cord-300883-rws11uel	46	1	These	these	DT
cord-300883-rws11uel	46	2	lines	line	NNS
cord-300883-rws11uel	46	3	of	of	IN
cord-300883-rws11uel	46	4	evidence	evidence	NN
cord-300883-rws11uel	46	5	suggest	suggest	VBP
cord-300883-rws11uel	46	6	an	an	DT
cord-300883-rws11uel	46	7	interesting	interesting	JJ
cord-300883-rws11uel	46	8	evolutionary	evolutionary	JJ
cord-300883-rws11uel	46	9	pattern	pattern	NN
cord-300883-rws11uel	46	10	of	of	IN
cord-300883-rws11uel	46	11	the	the	DT
cord-300883-rws11uel	46	12	respiratory	respiratory	JJ
cord-300883-rws11uel	46	13	viruses	virus	NNS
cord-300883-rws11uel	46	14	.	.	.
cord-300883-rws11uel	47	1	At	at	IN
cord-300883-rws11uel	47	2	the	the	DT
cord-300883-rws11uel	47	3	genomic	genomic	JJ
cord-300883-rws11uel	47	4	level	level	NN
cord-300883-rws11uel	47	5	,	,	,
cord-300883-rws11uel	47	6	whether	whether	IN
cord-300883-rws11uel	47	7	a	a	DT
cord-300883-rws11uel	47	8	gene	gene	NN
cord-300883-rws11uel	47	9	,	,	,
cord-300883-rws11uel	47	10	or	or	CC
cord-300883-rws11uel	47	11	a	a	DT
cord-300883-rws11uel	47	12	particular	particular	JJ
cord-300883-rws11uel	47	13	amino	amino	NN
cord-300883-rws11uel	47	14	acid	acid	NN
cord-300883-rws11uel	47	15	within	within	IN
cord-300883-rws11uel	47	16	a	a	DT
cord-300883-rws11uel	47	17	gene	gene	NN
cord-300883-rws11uel	47	18	,	,	,
cord-300883-rws11uel	47	19	is	be	VBZ
cord-300883-rws11uel	47	20	under	under	IN
cord-300883-rws11uel	47	21	relaxed	relaxed	JJ
cord-300883-rws11uel	47	22	selection	selection	NN
cord-300883-rws11uel	47	23	or	or	CC
cord-300883-rws11uel	47	24	remains	remain	VBZ
cord-300883-rws11uel	47	25	functionally	functionally	RB
cord-300883-rws11uel	47	26	constrained	constrain	VBN
cord-300883-rws11uel	47	27	throughout	throughout	IN
cord-300883-rws11uel	47	28	evolution	evolution	NN
cord-300883-rws11uel	47	29	can	can	MD
cord-300883-rws11uel	47	30	be	be	VB
cord-300883-rws11uel	47	31	detected	detect	VBN
cord-300883-rws11uel	47	32	by	by	IN
cord-300883-rws11uel	47	33	comparing	compare	VBG
cord-300883-rws11uel	47	34	the	the	DT
cord-300883-rws11uel	47	35	rate	rate	NN
cord-300883-rws11uel	47	36	of	of	IN
cord-300883-rws11uel	47	37	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	47	38	nucleotide	nucleotide	JJ
cord-300883-rws11uel	47	39	substitutions	substitution	NNS
cord-300883-rws11uel	47	40	per	per	IN
cord-300883-rws11uel	47	41	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	47	42	site	site	NN
cord-300883-rws11uel	47	43	(	(	-LRB-
cord-300883-rws11uel	47	44	d	d	NNP
cord-300883-rws11uel	47	45	N	n	CD
cord-300883-rws11uel	47	46	)	)	-RRB-
cord-300883-rws11uel	47	47	with	with	IN
cord-300883-rws11uel	47	48	that	that	DT
cord-300883-rws11uel	47	49	of	of	IN
cord-300883-rws11uel	47	50	synonymous	synonymous	JJ
cord-300883-rws11uel	47	51	substitutions	substitution	NNS
cord-300883-rws11uel	47	52	per	per	IN
cord-300883-rws11uel	47	53	synonymous	synonymous	JJ
cord-300883-rws11uel	47	54	site	site	NN
cord-300883-rws11uel	47	55	(	(	-LRB-
cord-300883-rws11uel	47	56	d	d	NNP
cord-300883-rws11uel	47	57	S	S	NNP
cord-300883-rws11uel	47	58	)	)	-RRB-
cord-300883-rws11uel	47	59	(	(	-LRB-
cord-300883-rws11uel	48	1	Hughes	Hughes	NNP
cord-300883-rws11uel	48	2	and	and	CC
cord-300883-rws11uel	48	3	Nei	Nei	NNP
cord-300883-rws11uel	48	4	,	,	,
cord-300883-rws11uel	48	5	1989	1989	CD
cord-300883-rws11uel	48	6	)	)	-RRB-
cord-300883-rws11uel	48	7	.	.	.
cord-300883-rws11uel	49	1	If	if	IN
cord-300883-rws11uel	49	2	d	d	NN
cord-300883-rws11uel	49	3	N	N	NNP
cord-300883-rws11uel	49	4	/d	/d	NNP
cord-300883-rws11uel	49	5	S	S	NNP
cord-300883-rws11uel	49	6	(	(	-LRB-
cord-300883-rws11uel	49	7	hereafter	hereafter	RB
cord-300883-rws11uel	49	8	referred	refer	VBN
cord-300883-rws11uel	49	9	as	as	IN
cord-300883-rws11uel	49	10	ω	ω	NNP
cord-300883-rws11uel	49	11	)	)	-RRB-
cord-300883-rws11uel	49	12	is	be	VBZ
cord-300883-rws11uel	49	13	greater	great	JJR
cord-300883-rws11uel	49	14	than	than	IN
cord-300883-rws11uel	49	15	one	one	CD
cord-300883-rws11uel	49	16	,	,	,
cord-300883-rws11uel	49	17	then	then	RB
cord-300883-rws11uel	49	18	positive	positive	JJ
cord-300883-rws11uel	49	19	selection	selection	NN
cord-300883-rws11uel	49	20	is	be	VBZ
cord-300883-rws11uel	49	21	said	say	VBN
cord-300883-rws11uel	49	22	to	to	TO
cord-300883-rws11uel	49	23	be	be	VB
cord-300883-rws11uel	49	24	operating	operate	VBG
cord-300883-rws11uel	49	25	.	.	.
cord-300883-rws11uel	50	1	Alternatively	alternatively	RB
cord-300883-rws11uel	50	2	,	,	,
cord-300883-rws11uel	50	3	if	if	IN
cord-300883-rws11uel	50	4	ω	ω	NN
cord-300883-rws11uel	50	5	<	<	XX
cord-300883-rws11uel	50	6	1	1	CD
cord-300883-rws11uel	50	7	,	,	,
cord-300883-rws11uel	50	8	the	the	DT
cord-300883-rws11uel	50	9	gene	gene	NN
cord-300883-rws11uel	50	10	is	be	VBZ
cord-300883-rws11uel	50	11	under	under	IN
cord-300883-rws11uel	50	12	strong	strong	JJ
cord-300883-rws11uel	50	13	purifying	purifying	NN
cord-300883-rws11uel	50	14	selection	selection	NN
cord-300883-rws11uel	50	15	and	and	CC
cord-300883-rws11uel	50	16	presumed	presume	VBN
cord-300883-rws11uel	50	17	to	to	TO
cord-300883-rws11uel	50	18	be	be	VB
cord-300883-rws11uel	50	19	functionally	functionally	RB
cord-300883-rws11uel	50	20	constrained	constrain	VBN
cord-300883-rws11uel	50	21	.	.	.
cord-300883-rws11uel	51	1	Identifying	identify	VBG
cord-300883-rws11uel	51	2	genes	gene	NNS
cord-300883-rws11uel	51	3	that	that	WDT
cord-300883-rws11uel	51	4	have	have	VBP
cord-300883-rws11uel	51	5	evolved	evolve	VBN
cord-300883-rws11uel	51	6	by	by	IN
cord-300883-rws11uel	51	7	adaptation	adaptation	NN
cord-300883-rws11uel	51	8	is	be	VBZ
cord-300883-rws11uel	51	9	central	central	JJ
cord-300883-rws11uel	51	10	to	to	IN
cord-300883-rws11uel	51	11	understanding	understand	VBG
cord-300883-rws11uel	51	12	molecular	molecular	JJ
cord-300883-rws11uel	51	13	evolution	evolution	NN
cord-300883-rws11uel	51	14	.	.	.
cord-300883-rws11uel	52	1	However	however	RB
cord-300883-rws11uel	52	2	,	,	,
cord-300883-rws11uel	52	3	not	not	RB
cord-300883-rws11uel	52	4	all	all	DT
cord-300883-rws11uel	52	5	amino	amino	NN
cord-300883-rws11uel	52	6	acid	acid	JJ
cord-300883-rws11uel	52	7	differences	difference	NNS
cord-300883-rws11uel	52	8	observed	observe	VBD
cord-300883-rws11uel	52	9	among	among	IN
cord-300883-rws11uel	52	10	the	the	DT
cord-300883-rws11uel	52	11	closely	closely	RB
cord-300883-rws11uel	52	12	related	related	JJ
cord-300883-rws11uel	52	13	sequences	sequence	NNS
cord-300883-rws11uel	52	14	from	from	IN
cord-300883-rws11uel	52	15	ecologically	ecologically	RB
cord-300883-rws11uel	52	16	/	/	,
cord-300883-rws11uel	52	17	geographically	geographically	RB
cord-300883-rws11uel	52	18	isolated	isolate	VBN
cord-300883-rws11uel	52	19	strains	strain	NNS
cord-300883-rws11uel	52	20	are	be	VBP
cord-300883-rws11uel	52	21	adaptive	adaptive	JJ
cord-300883-rws11uel	53	1	(	(	-LRB-
cord-300883-rws11uel	53	2	e.g.	e.g.	RB
cord-300883-rws11uel	53	3	,	,	,
cord-300883-rws11uel	53	4	Zlateva	Zlateva	NNP
cord-300883-rws11uel	53	5	et	et	FW
cord-300883-rws11uel	53	6	al	al	NNP
cord-300883-rws11uel	53	7	.	.	NNP
cord-300883-rws11uel	53	8	,	,	,
cord-300883-rws11uel	53	9	2004	2004	CD
cord-300883-rws11uel	53	10	)	)	-RRB-
cord-300883-rws11uel	53	11	.	.	.
cord-300883-rws11uel	54	1	Therefore	therefore	RB
cord-300883-rws11uel	54	2	,	,	,
cord-300883-rws11uel	54	3	analyzing	analyze	VBG
cord-300883-rws11uel	54	4	patterns	pattern	NNS
cord-300883-rws11uel	54	5	of	of	IN
cord-300883-rws11uel	54	6	amino	amino	NN
cord-300883-rws11uel	54	7	acid	acid	NN
cord-300883-rws11uel	54	8	substitutions	substitution	NNS
cord-300883-rws11uel	54	9	would	would	MD
cord-300883-rws11uel	54	10	provide	provide	VB
cord-300883-rws11uel	54	11	insight	insight	NN
cord-300883-rws11uel	54	12	into	into	IN
cord-300883-rws11uel	54	13	understanding	understand	VBG
cord-300883-rws11uel	54	14	protein	protein	NN
cord-300883-rws11uel	54	15	adaptation	adaptation	NN
cord-300883-rws11uel	54	16	by	by	IN
cord-300883-rws11uel	54	17	identifying	identify	VBG
cord-300883-rws11uel	54	18	candidate	candidate	NN
cord-300883-rws11uel	54	19	codon	codon	NN
cord-300883-rws11uel	54	20	sites	site	NNS
cord-300883-rws11uel	54	21	on	on	IN
cord-300883-rws11uel	54	22	which	which	WDT
cord-300883-rws11uel	54	23	positive	positive	JJ
cord-300883-rws11uel	54	24	selection	selection	NN
cord-300883-rws11uel	54	25	has	have	VBZ
cord-300883-rws11uel	54	26	been	be	VBN
cord-300883-rws11uel	54	27	operating	operate	VBG
cord-300883-rws11uel	54	28	.	.	.
cord-300883-rws11uel	55	1	Identifying	identify	VBG
cord-300883-rws11uel	55	2	the	the	DT
cord-300883-rws11uel	55	3	positively	positively	RB
cord-300883-rws11uel	55	4	selected	select	VBN
cord-300883-rws11uel	55	5	amino	amino	NN
cord-300883-rws11uel	55	6	acid	acid	NN
cord-300883-rws11uel	55	7	sites	site	NNS
cord-300883-rws11uel	55	8	would	would	MD
cord-300883-rws11uel	55	9	also	also	RB
cord-300883-rws11uel	55	10	help	help	VB
cord-300883-rws11uel	55	11	in	in	IN
cord-300883-rws11uel	55	12	further	further	JJ
cord-300883-rws11uel	55	13	immunization	immunization	NN
cord-300883-rws11uel	55	14	studies	study	NNS
cord-300883-rws11uel	55	15	.	.	.
cord-300883-rws11uel	56	1	Maximum	maximum	JJ
cord-300883-rws11uel	56	2	likelihood	likelihood	NN
cord-300883-rws11uel	56	3	(	(	-LRB-
cord-300883-rws11uel	56	4	ML)-based	ml)-based	CD
cord-300883-rws11uel	56	5	codon	codon	NN
cord-300883-rws11uel	56	6	substitution	substitution	NN
cord-300883-rws11uel	56	7	models	model	NNS
cord-300883-rws11uel	56	8	,	,	,
cord-300883-rws11uel	56	9	which	which	WDT
cord-300883-rws11uel	56	10	account	account	VBP
cord-300883-rws11uel	56	11	for	for	IN
cord-300883-rws11uel	56	12	variable	variable	JJ
cord-300883-rws11uel	56	13	ω	ω	CD
cord-300883-rws11uel	56	14	ratios	ratio	NNS
cord-300883-rws11uel	56	15	among	among	IN
cord-300883-rws11uel	56	16	codon	codon	NN
cord-300883-rws11uel	56	17	sites	site	NNS
cord-300883-rws11uel	56	18	and	and	CC
cord-300883-rws11uel	56	19	detect	detect	VB
cord-300883-rws11uel	56	20	codon	codon	NN
cord-300883-rws11uel	56	21	sites	site	NNS
cord-300883-rws11uel	56	22	that	that	WDT
cord-300883-rws11uel	56	23	are	be	VBP
cord-300883-rws11uel	56	24	subjected	subject	VBN
cord-300883-rws11uel	56	25	to	to	IN
cord-300883-rws11uel	56	26	positive	positive	JJ
cord-300883-rws11uel	56	27	selection	selection	NN
cord-300883-rws11uel	56	28	(	(	-LRB-
cord-300883-rws11uel	56	29	Yang	Yang	NNP
cord-300883-rws11uel	56	30	et	et	NNP
cord-300883-rws11uel	56	31	al	al	NNP
cord-300883-rws11uel	56	32	.	.	NNP
cord-300883-rws11uel	56	33	,	,	,
cord-300883-rws11uel	56	34	2000	2000	CD
cord-300883-rws11uel	56	35	)	)	-RRB-
cord-300883-rws11uel	56	36	,	,	,
cord-300883-rws11uel	56	37	have	have	VBP
cord-300883-rws11uel	56	38	been	be	VBN
cord-300883-rws11uel	56	39	widely	widely	RB
cord-300883-rws11uel	56	40	used	use	VBN
cord-300883-rws11uel	56	41	in	in	IN
cord-300883-rws11uel	56	42	detecting	detect	VBG
cord-300883-rws11uel	56	43	positive	positive	JJ
cord-300883-rws11uel	56	44	selection	selection	NN
cord-300883-rws11uel	56	45	in	in	IN
cord-300883-rws11uel	56	46	a	a	DT
cord-300883-rws11uel	56	47	number	number	NN
cord-300883-rws11uel	56	48	of	of	IN
cord-300883-rws11uel	56	49	respiratory	respiratory	JJ
cord-300883-rws11uel	56	50	viral	viral	JJ
cord-300883-rws11uel	56	51	groups	group	NNS
cord-300883-rws11uel	56	52	(	(	-LRB-
cord-300883-rws11uel	56	53	e.g.	e.g.	RB
cord-300883-rws11uel	56	54	,	,	,
cord-300883-rws11uel	56	55	Zlateva	Zlateva	NNP
cord-300883-rws11uel	56	56	et	et	FW
cord-300883-rws11uel	56	57	al	al	NNP
cord-300883-rws11uel	56	58	.	.	.
cord-300883-rws11uel	57	1	,	,	,
cord-300883-rws11uel	57	2	2004	2004	CD
cord-300883-rws11uel	57	3	;	;	:
cord-300883-rws11uel	57	4	Zhang	Zhang	NNP
cord-300883-rws11uel	57	5	et	et	NNP
cord-300883-rws11uel	57	6	al	al	NNP
cord-300883-rws11uel	57	7	.	.	NNP
cord-300883-rws11uel	57	8	,	,	,
cord-300883-rws11uel	57	9	2006	2006	CD
cord-300883-rws11uel	57	10	)	)	-RRB-
cord-300883-rws11uel	57	11	.	.	.
cord-300883-rws11uel	58	1	Here	here	RB
cord-300883-rws11uel	58	2	we	-PRON-	PRP
cord-300883-rws11uel	58	3	used	use	VBD
cord-300883-rws11uel	58	4	Yang	Yang	NNP
cord-300883-rws11uel	58	5	et	et	NNP
cord-300883-rws11uel	58	6	al	al	NNP
cord-300883-rws11uel	58	7	's	's	POS
cord-300883-rws11uel	58	8	(	(	-LRB-
cord-300883-rws11uel	58	9	2000	2000	CD
cord-300883-rws11uel	58	10	)	)	-RRB-
cord-300883-rws11uel	59	1	ML	ml	NN
cord-300883-rws11uel	59	2	codon	codon	NN
cord-300883-rws11uel	59	3	substitution	substitution	NN
cord-300883-rws11uel	59	4	models	model	NNS
cord-300883-rws11uel	59	5	to	to	TO
cord-300883-rws11uel	59	6	test	test	VB
cord-300883-rws11uel	59	7	whether	whether	IN
cord-300883-rws11uel	59	8	there	there	EX
cord-300883-rws11uel	59	9	was	be	VBD
cord-300883-rws11uel	59	10	evidence	evidence	NN
cord-300883-rws11uel	59	11	at	at	IN
cord-300883-rws11uel	59	12	the	the	DT
cord-300883-rws11uel	59	13	nucleotide	nucleotide	JJ
cord-300883-rws11uel	59	14	sequence	sequence	NN
cord-300883-rws11uel	59	15	level	level	NN
cord-300883-rws11uel	59	16	that	that	IN
cord-300883-rws11uel	59	17	a	a	DT
cord-300883-rws11uel	59	18	subset	subset	NN
cord-300883-rws11uel	59	19	of	of	IN
cord-300883-rws11uel	59	20	amino	amino	JJ
cord-300883-rws11uel	59	21	acid	acid	NN
cord-300883-rws11uel	59	22	sites	site	NNS
cord-300883-rws11uel	59	23	in	in	IN
cord-300883-rws11uel	59	24	G	g	NN
cord-300883-rws11uel	59	25	-	-	HYPH
cord-300883-rws11uel	59	26	protein	protein	NN
cord-300883-rws11uel	59	27	of	of	IN
cord-300883-rws11uel	59	28	hMPV	hmpv	NN
cord-300883-rws11uel	59	29	sequences	sequence	NNS
cord-300883-rws11uel	59	30	that	that	WDT
cord-300883-rws11uel	59	31	represent	represent	VBP
cord-300883-rws11uel	59	32	each	each	DT
cord-300883-rws11uel	59	33	subgroup	subgroup	NN
cord-300883-rws11uel	59	34	has	have	VBZ
cord-300883-rws11uel	59	35	been	be	VBN
cord-300883-rws11uel	59	36	under	under	IN
cord-300883-rws11uel	59	37	positive	positive	JJ
cord-300883-rws11uel	59	38	selection	selection	NN
cord-300883-rws11uel	59	39	.	.	.
cord-300883-rws11uel	60	1	In	in	IN
cord-300883-rws11uel	60	2	addition	addition	NN
cord-300883-rws11uel	60	3	,	,	,
cord-300883-rws11uel	60	4	we	-PRON-	PRP
cord-300883-rws11uel	60	5	used	use	VBD
cord-300883-rws11uel	60	6	a	a	DT
cord-300883-rws11uel	60	7	Bayesian	Bayesian	NNP
cord-300883-rws11uel	60	8	MCMC	MCMC	NNP
cord-300883-rws11uel	60	9	approach	approach	NN
cord-300883-rws11uel	60	10	implemented	implement	VBN
cord-300883-rws11uel	60	11	in	in	IN
cord-300883-rws11uel	60	12	BEAST	BEAST	NNP
cord-300883-rws11uel	60	13	version	version	NN
cord-300883-rws11uel	60	14	1.4.4	1.4.4	CD
cord-300883-rws11uel	60	15	)	)	-RRB-
cord-300883-rws11uel	60	16	that	that	WDT
cord-300883-rws11uel	60	17	utilize	utilize	VBP
cord-300883-rws11uel	60	18	the	the	DT
cord-300883-rws11uel	60	19	number	number	NN
cord-300883-rws11uel	60	20	and	and	CC
cord-300883-rws11uel	60	21	temporal	temporal	JJ
cord-300883-rws11uel	60	22	distribution	distribution	NN
cord-300883-rws11uel	60	23	of	of	IN
cord-300883-rws11uel	60	24	genetic	genetic	JJ
cord-300883-rws11uel	60	25	differences	difference	NNS
cord-300883-rws11uel	60	26	among	among	IN
cord-300883-rws11uel	60	27	viruses	virus	NNS
cord-300883-rws11uel	60	28	sampled	sample	VBN
cord-300883-rws11uel	60	29	at	at	IN
cord-300883-rws11uel	60	30	different	different	JJ
cord-300883-rws11uel	60	31	times	time	NNS
cord-300883-rws11uel	60	32	(	(	-LRB-
cord-300883-rws11uel	60	33	Drummond	Drummond	NNP
cord-300883-rws11uel	60	34	et	et	NNP
cord-300883-rws11uel	60	35	al	al	NNP
cord-300883-rws11uel	60	36	.	.	NNP
cord-300883-rws11uel	60	37	,	,	,
cord-300883-rws11uel	60	38	2002	2002	CD
cord-300883-rws11uel	60	39	to	to	TO
cord-300883-rws11uel	60	40	estimate	estimate	VB
cord-300883-rws11uel	60	41	the	the	DT
cord-300883-rws11uel	60	42	evolutionary	evolutionary	JJ
cord-300883-rws11uel	60	43	change	change	NN
cord-300883-rws11uel	60	44	for	for	IN
cord-300883-rws11uel	60	45	each	each	DT
cord-300883-rws11uel	60	46	lineage	lineage	NN
cord-300883-rws11uel	60	47	.	.	.
cord-300883-rws11uel	61	1	A	a	DT
cord-300883-rws11uel	61	2	total	total	NN
cord-300883-rws11uel	61	3	of	of	IN
cord-300883-rws11uel	61	4	144	144	CD
cord-300883-rws11uel	61	5	published	publish	VBN
cord-300883-rws11uel	61	6	unique	unique	JJ
cord-300883-rws11uel	61	7	nucleotide	nucleotide	JJ
cord-300883-rws11uel	61	8	coding	coding	NN
cord-300883-rws11uel	61	9	sequences	sequence	NNS
cord-300883-rws11uel	61	10	of	of	IN
cord-300883-rws11uel	61	11	G	g	NN
cord-300883-rws11uel	61	12	-	-	HYPH
cord-300883-rws11uel	61	13	protein	protein	NN
cord-300883-rws11uel	61	14	representing	represent	VBG
cord-300883-rws11uel	61	15	four	four	CD
cord-300883-rws11uel	61	16	sub	sub	NN
cord-300883-rws11uel	61	17	-	-	NNS
cord-300883-rws11uel	61	18	lineages	lineage	NNS
cord-300883-rws11uel	61	19	(	(	-LRB-
cord-300883-rws11uel	61	20	1a	1a	NN
cord-300883-rws11uel	61	21	=	=	SYM
cord-300883-rws11uel	61	22	46	46	CD
cord-300883-rws11uel	61	23	,	,	,
cord-300883-rws11uel	61	24	1b	1b	CD
cord-300883-rws11uel	61	25	=	=	SYM
cord-300883-rws11uel	61	26	40	40	CD
cord-300883-rws11uel	61	27	,	,	,
cord-300883-rws11uel	61	28	2a	2a	CD
cord-300883-rws11uel	61	29	=	=	SYM
cord-300883-rws11uel	61	30	38	38	CD
cord-300883-rws11uel	61	31	,	,	,
cord-300883-rws11uel	61	32	2b	2b	CD
cord-300883-rws11uel	61	33	=	=	SYM
cord-300883-rws11uel	61	34	20	20	CD
cord-300883-rws11uel	61	35	)	)	-RRB-
cord-300883-rws11uel	61	36	were	be	VBD
cord-300883-rws11uel	61	37	retrieved	retrieve	VBN
cord-300883-rws11uel	61	38	from	from	IN
cord-300883-rws11uel	61	39	GenBank	GenBank	NNP
cord-300883-rws11uel	61	40	(	(	-LRB-
cord-300883-rws11uel	61	41	Table	table	NN
cord-300883-rws11uel	61	42	1	1	CD
cord-300883-rws11uel	61	43	)	)	-RRB-
cord-300883-rws11uel	61	44	.	.	.
cord-300883-rws11uel	62	1	Sequences	sequence	NNS
cord-300883-rws11uel	62	2	were	be	VBD
cord-300883-rws11uel	62	3	aligned	align	VBN
cord-300883-rws11uel	62	4	using	use	VBG
cord-300883-rws11uel	62	5	Mesquite	Mesquite	NNP
cord-300883-rws11uel	62	6	version	version	NN
cord-300883-rws11uel	62	7	1.2	1.2	CD
cord-300883-rws11uel	62	8	(	(	-LRB-
cord-300883-rws11uel	62	9	Maddison	Maddison	NNP
cord-300883-rws11uel	62	10	and	and	CC
cord-300883-rws11uel	62	11	Maddison	Maddison	NNP
cord-300883-rws11uel	62	12	,	,	,
cord-300883-rws11uel	62	13	2006	2006	CD
cord-300883-rws11uel	62	14	)	)	-RRB-
cord-300883-rws11uel	62	15	,	,	,
cord-300883-rws11uel	62	16	DAMBE	DAMBE	NNP
cord-300883-rws11uel	62	17	version	version	NN
cord-300883-rws11uel	62	18	4.5.2	4.5.2	CD
cord-300883-rws11uel	62	19	(	(	-LRB-
cord-300883-rws11uel	62	20	Xia	Xia	NNP
cord-300883-rws11uel	62	21	,	,	,
cord-300883-rws11uel	62	22	2000	2000	CD
cord-300883-rws11uel	62	23	;	;	:
cord-300883-rws11uel	63	1	Xia	Xia	NNP
cord-300883-rws11uel	63	2	and	and	CC
cord-300883-rws11uel	63	3	Xie	Xie	NNP
cord-300883-rws11uel	63	4	,	,	,
cord-300883-rws11uel	63	5	2001	2001	CD
cord-300883-rws11uel	63	6	)	)	-RRB-
cord-300883-rws11uel	63	7	,	,	,
cord-300883-rws11uel	63	8	and	and	CC
cord-300883-rws11uel	63	9	BioEdit	BioEdit	NNP
cord-300883-rws11uel	63	10	version	version	NN
cord-300883-rws11uel	63	11	7.0.5.3	7.0.5.3	CD
cord-300883-rws11uel	63	12	(	(	-LRB-
cord-300883-rws11uel	63	13	Hall	Hall	NNP
cord-300883-rws11uel	63	14	,	,	,
cord-300883-rws11uel	63	15	1999	1999	CD
cord-300883-rws11uel	63	16	)	)	-RRB-
cord-300883-rws11uel	63	17	software	software	NN
cord-300883-rws11uel	63	18	packages	package	NNS
cord-300883-rws11uel	63	19	.	.	.
cord-300883-rws11uel	64	1	To	to	TO
cord-300883-rws11uel	64	2	infer	infer	VB
cord-300883-rws11uel	64	3	phylogenetic	phylogenetic	JJ
cord-300883-rws11uel	64	4	relationship	relationship	NN
cord-300883-rws11uel	64	5	among	among	IN
cord-300883-rws11uel	64	6	these	these	DT
cord-300883-rws11uel	64	7	strains	strain	NNS
cord-300883-rws11uel	64	8	of	of	IN
cord-300883-rws11uel	64	9	hMPVs	hmpvs	CD
cord-300883-rws11uel	64	10	,	,	,
cord-300883-rws11uel	64	11	we	-PRON-	PRP
cord-300883-rws11uel	64	12	reconstructed	reconstruct	VBD
cord-300883-rws11uel	64	13	a	a	DT
cord-300883-rws11uel	64	14	neighbor	neighbor	NN
cord-300883-rws11uel	64	15	joining	join	VBG
cord-300883-rws11uel	64	16	tree	tree	NN
cord-300883-rws11uel	64	17	from	from	IN
cord-300883-rws11uel	64	18	their	-PRON-	PRP$
cord-300883-rws11uel	64	19	predicted	predict	VBN
cord-300883-rws11uel	64	20	amino	amino	NN
cord-300883-rws11uel	64	21	acid	acid	NN
cord-300883-rws11uel	64	22	sequence	sequence	NN
cord-300883-rws11uel	64	23	data	datum	NNS
cord-300883-rws11uel	64	24	with	with	IN
cord-300883-rws11uel	64	25	p	p	NN
cord-300883-rws11uel	64	26	-	-	HYPH
cord-300883-rws11uel	64	27	distance	distance	NN
cord-300883-rws11uel	64	28	implemented	implement	VBN
cord-300883-rws11uel	64	29	in	in	IN
cord-300883-rws11uel	64	30	MEGA	MEGA	NNP
cord-300883-rws11uel	64	31	version	version	NN
cord-300883-rws11uel	64	32	3.1	3.1	CD
cord-300883-rws11uel	65	1	(	(	-LRB-
cord-300883-rws11uel	65	2	Kumar	Kumar	NNP
cord-300883-rws11uel	65	3	et	et	NNP
cord-300883-rws11uel	65	4	al	al	NNP
cord-300883-rws11uel	65	5	.	.	NNP
cord-300883-rws11uel	65	6	,	,	,
cord-300883-rws11uel	65	7	2004	2004	CD
cord-300883-rws11uel	65	8	)	)	-RRB-
cord-300883-rws11uel	65	9	.	.	.
cord-300883-rws11uel	66	1	Using	use	VBG
cord-300883-rws11uel	66	2	the	the	DT
cord-300883-rws11uel	66	3	same	same	JJ
cord-300883-rws11uel	66	4	program	program	NN
cord-300883-rws11uel	66	5	,	,	,
cord-300883-rws11uel	66	6	nodal	nodal	NN
cord-300883-rws11uel	66	7	supports	support	NNS
cord-300883-rws11uel	66	8	were	be	VBD
cord-300883-rws11uel	66	9	estimated	estimate	VBN
cord-300883-rws11uel	66	10	with	with	IN
cord-300883-rws11uel	66	11	10,000	10,000	CD
cord-300883-rws11uel	66	12	nonparametric	nonparametric	JJ
cord-300883-rws11uel	66	13	bootstrap	bootstrap	NN
cord-300883-rws11uel	66	14	replicates	replicate	NNS
cord-300883-rws11uel	66	15	.	.	.
cord-300883-rws11uel	67	1	For	for	IN
cord-300883-rws11uel	67	2	selection	selection	NN
cord-300883-rws11uel	67	3	analyses	analysis	NNS
cord-300883-rws11uel	67	4	,	,	,
cord-300883-rws11uel	67	5	we	-PRON-	PRP
cord-300883-rws11uel	67	6	reconstructed	reconstruct	VBD
cord-300883-rws11uel	67	7	unrooted	unrooted	JJ
cord-300883-rws11uel	67	8	ML	ML	NNP
cord-300883-rws11uel	67	9	trees	tree	NNS
cord-300883-rws11uel	67	10	for	for	IN
cord-300883-rws11uel	67	11	each	each	DT
cord-300883-rws11uel	67	12	lineage	lineage	NN
cord-300883-rws11uel	67	13	from	from	IN
cord-300883-rws11uel	67	14	their	-PRON-	PRP$
cord-300883-rws11uel	67	15	respective	respective	JJ
cord-300883-rws11uel	67	16	nucleotide	nucleotide	JJ
cord-300883-rws11uel	67	17	sequence	sequence	NN
cord-300883-rws11uel	67	18	data	datum	NNS
cord-300883-rws11uel	67	19	using	use	VBG
cord-300883-rws11uel	67	20	the	the	DT
cord-300883-rws11uel	67	21	appropriate	appropriate	JJ
cord-300883-rws11uel	67	22	nucleotide	nucleotide	JJ
cord-300883-rws11uel	67	23	substitution	substitution	NN
cord-300883-rws11uel	67	24	model	model	NN
cord-300883-rws11uel	67	25	identified	identify	VBN
cord-300883-rws11uel	67	26	by	by	IN
cord-300883-rws11uel	67	27	the	the	DT
cord-300883-rws11uel	67	28	hierarchical	hierarchical	JJ
cord-300883-rws11uel	67	29	likelihood	likelihood	NN
cord-300883-rws11uel	67	30	ratio	ratio	NN
cord-300883-rws11uel	67	31	test	test	NN
cord-300883-rws11uel	67	32	implemented	implement	VBN
cord-300883-rws11uel	67	33	in	in	IN
cord-300883-rws11uel	67	34	Modeltest	Modeltest	NNP
cord-300883-rws11uel	67	35	version	version	NN
cord-300883-rws11uel	67	36	3.5	3.5	CD
cord-300883-rws11uel	67	37	(	(	-LRB-
cord-300883-rws11uel	67	38	Posada	Posada	NNP
cord-300883-rws11uel	67	39	and	and	CC
cord-300883-rws11uel	67	40	Crandall	Crandall	NNP
cord-300883-rws11uel	67	41	,	,	,
cord-300883-rws11uel	67	42	1998	1998	CD
cord-300883-rws11uel	67	43	)	)	-RRB-
cord-300883-rws11uel	67	44	.	.	.
cord-300883-rws11uel	68	1	PHYML	PHYML	NNP
cord-300883-rws11uel	68	2	version	version	NN
cord-300883-rws11uel	68	3	2.4.4	2.4.4	CD
cord-300883-rws11uel	68	4	(	(	-LRB-
cord-300883-rws11uel	68	5	Guindon	Guindon	NNP
cord-300883-rws11uel	68	6	and	and	CC
cord-300883-rws11uel	68	7	Gascuel	Gascuel	NNP
cord-300883-rws11uel	68	8	,	,	,
cord-300883-rws11uel	68	9	2003	2003	CD
cord-300883-rws11uel	68	10	)	)	-RRB-
cord-300883-rws11uel	68	11	was	be	VBD
cord-300883-rws11uel	68	12	used	use	VBN
cord-300883-rws11uel	68	13	to	to	TO
cord-300883-rws11uel	68	14	conduct	conduct	VB
cord-300883-rws11uel	68	15	ML	ml	NN
cord-300883-rws11uel	68	16	analyses	analysis	NNS
cord-300883-rws11uel	68	17	.	.	.
cord-300883-rws11uel	69	1	Overall	overall	JJ
cord-300883-rws11uel	69	2	substitution	substitution	NN
cord-300883-rws11uel	69	3	rate	rate	NN
cord-300883-rws11uel	69	4	(	(	-LRB-
cord-300883-rws11uel	69	5	nucleotide	nucleotide	JJ
cord-300883-rws11uel	69	6	substitutions	substitution	NNS
cord-300883-rws11uel	69	7	per	per	IN
cord-300883-rws11uel	69	8	site	site	NN
cord-300883-rws11uel	69	9	per	per	IN
cord-300883-rws11uel	69	10	year	year	NN
cord-300883-rws11uel	69	11	)	)	-RRB-
cord-300883-rws11uel	69	12	of	of	IN
cord-300883-rws11uel	69	13	each	each	DT
cord-300883-rws11uel	69	14	lineage	lineage	NN
cord-300883-rws11uel	69	15	was	be	VBD
cord-300883-rws11uel	69	16	estimated	estimate	VBN
cord-300883-rws11uel	69	17	using	use	VBG
cord-300883-rws11uel	69	18	the	the	DT
cord-300883-rws11uel	69	19	Bayesian	bayesian	JJ
cord-300883-rws11uel	69	20	skyline	skyline	NN
cord-300883-rws11uel	69	21	model	model	NN
cord-300883-rws11uel	69	22	,	,	,
cord-300883-rws11uel	69	23	with	with	IN
cord-300883-rws11uel	69	24	both	both	CC
cord-300883-rws11uel	69	25	relaxed	relaxed	JJ
cord-300883-rws11uel	69	26	(	(	-LRB-
cord-300883-rws11uel	69	27	variable	variable	JJ
cord-300883-rws11uel	69	28	)	)	-RRB-
cord-300883-rws11uel	69	29	molecular	molecular	JJ
cord-300883-rws11uel	69	30	clock	clock	NN
cord-300883-rws11uel	69	31	(	(	-LRB-
cord-300883-rws11uel	69	32	with	with	IN
cord-300883-rws11uel	69	33	uncorrelated	uncorrelated	JJ
cord-300883-rws11uel	69	34	lognormal	lognormal	JJ
cord-300883-rws11uel	69	35	model	model	NN
cord-300883-rws11uel	69	36	)	)	-RRB-
cord-300883-rws11uel	69	37	and	and	CC
cord-300883-rws11uel	69	38	strict	strict	JJ
cord-300883-rws11uel	69	39	clock	clock	NN
cord-300883-rws11uel	69	40	implemented	implement	VBN
cord-300883-rws11uel	69	41	in	in	IN
cord-300883-rws11uel	69	42	the	the	DT
cord-300883-rws11uel	69	43	BEAST	BEAST	NNP
cord-300883-rws11uel	69	44	version	version	NN
cord-300883-rws11uel	69	45	1.4.4	1.4.4	CD
cord-300883-rws11uel	69	46	.	.	.
cord-300883-rws11uel	70	1	This	this	DT
cord-300883-rws11uel	70	2	model	model	NN
cord-300883-rws11uel	70	3	employs	employ	VBZ
cord-300883-rws11uel	70	4	a	a	DT
cord-300883-rws11uel	70	5	Bayesian	Bayesian	NNP
cord-300883-rws11uel	70	6	MCMC	MCMC	NNP
cord-300883-rws11uel	70	7	approach	approach	NN
cord-300883-rws11uel	70	8	and	and	CC
cord-300883-rws11uel	70	9	utilize	utilize	VB
cord-300883-rws11uel	70	10	the	the	DT
cord-300883-rws11uel	70	11	number	number	NN
cord-300883-rws11uel	70	12	and	and	CC
cord-300883-rws11uel	70	13	temporal	temporal	JJ
cord-300883-rws11uel	70	14	distribution	distribution	NN
cord-300883-rws11uel	70	15	of	of	IN
cord-300883-rws11uel	70	16	genetic	genetic	JJ
cord-300883-rws11uel	70	17	differences	difference	NNS
cord-300883-rws11uel	70	18	among	among	IN
cord-300883-rws11uel	70	19	viruses	virus	NNS
cord-300883-rws11uel	70	20	sampled	sample	VBN
cord-300883-rws11uel	70	21	at	at	IN
cord-300883-rws11uel	70	22	different	different	JJ
cord-300883-rws11uel	70	23	times	time	NNS
cord-300883-rws11uel	70	24	(	(	-LRB-
cord-300883-rws11uel	70	25	Drummond	Drummond	NNP
cord-300883-rws11uel	70	26	et	et	NNP
cord-300883-rws11uel	70	27	al	al	NNP
cord-300883-rws11uel	70	28	.	.	NNP
cord-300883-rws11uel	70	29	,	,	,
cord-300883-rws11uel	70	30	2002	2002	CD
cord-300883-rws11uel	70	31	.	.	.
cord-300883-rws11uel	71	1	Bayesian	Bayesian	NNP
cord-300883-rws11uel	71	2	skyline	skyline	NN
cord-300883-rws11uel	71	3	plots	plot	NNS
cord-300883-rws11uel	71	4	with	with	IN
cord-300883-rws11uel	71	5	10	10	CD
cord-300883-rws11uel	71	6	grouped	group	VBN
cord-300883-rws11uel	71	7	intervals	interval	NNS
cord-300883-rws11uel	71	8	were	be	VBD
cord-300883-rws11uel	71	9	reconstructed	reconstruct	VBN
cord-300883-rws11uel	71	10	to	to	TO
cord-300883-rws11uel	71	11	infer	infer	VB
cord-300883-rws11uel	71	12	demographic	demographic	JJ
cord-300883-rws11uel	71	13	history	history	NN
cord-300883-rws11uel	71	14	(	(	-LRB-
cord-300883-rws11uel	71	15	Drummond	Drummond	NNP
cord-300883-rws11uel	71	16	et	et	NNP
cord-300883-rws11uel	71	17	al	al	NNP
cord-300883-rws11uel	71	18	.	.	NNP
cord-300883-rws11uel	71	19	,	,	,
cord-300883-rws11uel	71	20	2005	2005	CD
cord-300883-rws11uel	71	21	)	)	-RRB-
cord-300883-rws11uel	71	22	.	.	.
cord-300883-rws11uel	72	1	Phylogenies	phylogeny	NNS
cord-300883-rws11uel	72	2	were	be	VBD
cord-300883-rws11uel	72	3	evaluated	evaluate	VBN
cord-300883-rws11uel	72	4	using	use	VBG
cord-300883-rws11uel	72	5	a	a	DT
cord-300883-rws11uel	72	6	chain	chain	NN
cord-300883-rws11uel	72	7	length	length	NN
cord-300883-rws11uel	72	8	of	of	IN
cord-300883-rws11uel	72	9	30	30	CD
cord-300883-rws11uel	72	10	million	million	CD
cord-300883-rws11uel	72	11	states	state	NNS
cord-300883-rws11uel	72	12	under	under	IN
cord-300883-rws11uel	72	13	the	the	DT
cord-300883-rws11uel	72	14	HKY85	HKY85	NNP
cord-300883-rws11uel	72	15	+	+	SYM
cord-300883-rws11uel	72	16	4	4	CD
cord-300883-rws11uel	72	17	substitution	substitution	NN
cord-300883-rws11uel	72	18	model	model	NN
cord-300883-rws11uel	72	19	and	and	CC
cord-300883-rws11uel	72	20	with	with	IN
cord-300883-rws11uel	72	21	uncertainty	uncertainty	NN
cord-300883-rws11uel	72	22	in	in	IN
cord-300883-rws11uel	72	23	the	the	DT
cord-300883-rws11uel	72	24	data	datum	NNS
cord-300883-rws11uel	72	25	reflected	reflect	VBN
cord-300883-rws11uel	72	26	in	in	IN
cord-300883-rws11uel	72	27	the	the	DT
cord-300883-rws11uel	72	28	95	95	CD
cord-300883-rws11uel	72	29	%	%	NN
cord-300883-rws11uel	72	30	high	high	JJ
cord-300883-rws11uel	72	31	-	-	HYPH
cord-300883-rws11uel	72	32	probability	probability	NN
cord-300883-rws11uel	72	33	density	density	NN
cord-300883-rws11uel	72	34	(	(	-LRB-
cord-300883-rws11uel	72	35	HPD	HPD	NNP
cord-300883-rws11uel	72	36	)	)	-RRB-
cord-300883-rws11uel	72	37	intervals	interval	NNS
cord-300883-rws11uel	72	38	.	.	.
cord-300883-rws11uel	73	1	Convergence	convergence	NN
cord-300883-rws11uel	73	2	of	of	IN
cord-300883-rws11uel	73	3	trees	tree	NNS
cord-300883-rws11uel	73	4	was	be	VBD
cord-300883-rws11uel	73	5	checked	check	VBN
cord-300883-rws11uel	73	6	using	use	VBG
cord-300883-rws11uel	73	7	Tracer	Tracer	NNP
cord-300883-rws11uel	73	8	version	version	NN
cord-300883-rws11uel	73	9	1.3	1.3	CD
cord-300883-rws11uel	73	10	.	.	.
cord-300883-rws11uel	74	1	To	to	TO
cord-300883-rws11uel	74	2	determine	determine	VB
cord-300883-rws11uel	74	3	the	the	DT
cord-300883-rws11uel	74	4	synonymous	synonymous	JJ
cord-300883-rws11uel	74	5	and	and	CC
cord-300883-rws11uel	74	6	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	74	7	sequence	sequence	NN
cord-300883-rws11uel	74	8	divergence	divergence	NN
cord-300883-rws11uel	74	9	distribution	distribution	NN
cord-300883-rws11uel	74	10	pattern	pattern	NN
cord-300883-rws11uel	74	11	across	across	IN
cord-300883-rws11uel	74	12	the	the	DT
cord-300883-rws11uel	74	13	entire	entire	JJ
cord-300883-rws11uel	74	14	coding	code	VBG
cord-300883-rws11uel	74	15	region	region	NN
cord-300883-rws11uel	74	16	of	of	IN
cord-300883-rws11uel	74	17	each	each	DT
cord-300883-rws11uel	74	18	lineage	lineage	NN
cord-300883-rws11uel	74	19	(	(	-LRB-
cord-300883-rws11uel	74	20	Fig	Fig	NNP
cord-300883-rws11uel	74	21	.	.	.
cord-300883-rws11uel	74	22	1	1	CD
cord-300883-rws11uel	74	23	)	)	-RRB-
cord-300883-rws11uel	74	24	,	,	,
cord-300883-rws11uel	74	25	we	-PRON-	PRP
cord-300883-rws11uel	74	26	used	use	VBD
cord-300883-rws11uel	74	27	a	a	DT
cord-300883-rws11uel	74	28	sliding	slide	VBG
cord-300883-rws11uel	74	29	window	window	NN
cord-300883-rws11uel	74	30	approach	approach	NN
cord-300883-rws11uel	74	31	(	(	-LRB-
cord-300883-rws11uel	74	32	window	window	NN
cord-300883-rws11uel	74	33	size	size	NN
cord-300883-rws11uel	74	34	=	=	SYM
cord-300883-rws11uel	74	35	6	6	CD
cord-300883-rws11uel	74	36	,	,	,
cord-300883-rws11uel	74	37	step	step	NN
cord-300883-rws11uel	74	38	=	=	SYM
cord-300883-rws11uel	74	39	1	1	CD
cord-300883-rws11uel	74	40	)	)	-RRB-
cord-300883-rws11uel	74	41	implemented	implement	VBN
cord-300883-rws11uel	74	42	in	in	IN
cord-300883-rws11uel	74	43	DNAsp	DNAsp	NNP
cord-300883-rws11uel	74	44	version	version	NN
cord-300883-rws11uel	74	45	4.0	4.0	CD
cord-300883-rws11uel	75	1	(	(	-LRB-
cord-300883-rws11uel	75	2	Rozas	Rozas	NNP
cord-300883-rws11uel	75	3	et	et	NNP
cord-300883-rws11uel	75	4	al	al	NNP
cord-300883-rws11uel	75	5	.	.	NNP
cord-300883-rws11uel	75	6	,	,	,
cord-300883-rws11uel	75	7	2003	2003	CD
cord-300883-rws11uel	75	8	)	)	-RRB-
cord-300883-rws11uel	75	9	.	.	.
cord-300883-rws11uel	76	1	To	to	TO
cord-300883-rws11uel	76	2	assess	assess	VB
cord-300883-rws11uel	76	3	whether	whether	IN
cord-300883-rws11uel	76	4	positive	positive	JJ
cord-300883-rws11uel	76	5	selection	selection	NN
cord-300883-rws11uel	76	6	is	be	VBZ
cord-300883-rws11uel	76	7	operating	operate	VBG
cord-300883-rws11uel	76	8	in	in	IN
cord-300883-rws11uel	76	9	any	any	DT
cord-300883-rws11uel	76	10	codon	codon	NN
cord-300883-rws11uel	76	11	sites	site	NNS
cord-300883-rws11uel	76	12	,	,	,
cord-300883-rws11uel	76	13	we	-PRON-	PRP
cord-300883-rws11uel	76	14	used	use	VBD
cord-300883-rws11uel	76	15	the	the	DT
cord-300883-rws11uel	76	16	alignment	alignment	NN
cord-300883-rws11uel	76	17	and	and	CC
cord-300883-rws11uel	76	18	ML	ml	NN
cord-300883-rws11uel	76	19	trees	tree	NNS
cord-300883-rws11uel	76	20	of	of	IN
cord-300883-rws11uel	76	21	respective	respective	JJ
cord-300883-rws11uel	76	22	lineages	lineage	NNS
cord-300883-rws11uel	76	23	as	as	IN
cord-300883-rws11uel	76	24	input	input	NN
cord-300883-rws11uel	76	25	for	for	IN
cord-300883-rws11uel	76	26	the	the	DT
cord-300883-rws11uel	76	27	CODEML	CODEML	NNP
cord-300883-rws11uel	76	28	program	program	NN
cord-300883-rws11uel	76	29	of	of	IN
cord-300883-rws11uel	76	30	PAML	PAML	NNP
cord-300883-rws11uel	76	31	version	version	NN
cord-300883-rws11uel	76	32	3.15	3.15	CD
cord-300883-rws11uel	77	1	(	(	-LRB-
cord-300883-rws11uel	77	2	Yang	Yang	NNP
cord-300883-rws11uel	77	3	,	,	,
cord-300883-rws11uel	77	4	1997	1997	CD
cord-300883-rws11uel	77	5	)	)	-RRB-
cord-300883-rws11uel	77	6	.	.	.
cord-300883-rws11uel	78	1	The	the	DT
cord-300883-rws11uel	78	2	PAML	PAML	NNP
cord-300883-rws11uel	78	3	program	program	NN
cord-300883-rws11uel	78	4	incorporates	incorporate	VBZ
cord-300883-rws11uel	78	5	six	six	CD
cord-300883-rws11uel	78	6	different	different	JJ
cord-300883-rws11uel	78	7	codon	codon	NN
cord-300883-rws11uel	78	8	substitution	substitution	NN
cord-300883-rws11uel	78	9	models	model	NNS
cord-300883-rws11uel	78	10	that	that	WDT
cord-300883-rws11uel	78	11	account	account	VBP
cord-300883-rws11uel	78	12	for	for	IN
cord-300883-rws11uel	78	13	variable	variable	JJ
cord-300883-rws11uel	78	14	ω	ω	NN
cord-300883-rws11uel	78	15	for	for	IN
cord-300883-rws11uel	78	16	each	each	DT
cord-300883-rws11uel	78	17	codon	codon	NN
cord-300883-rws11uel	78	18	site	site	NN
cord-300883-rws11uel	78	19	.	.	.
cord-300883-rws11uel	79	1	The	the	DT
cord-300883-rws11uel	79	2	six	six	CD
cord-300883-rws11uel	79	3	codon	codon	NN
cord-300883-rws11uel	79	4	substitution	substitution	NN
cord-300883-rws11uel	79	5	models	model	NNS
cord-300883-rws11uel	79	6	are	be	VBP
cord-300883-rws11uel	79	7	:	:	:
cord-300883-rws11uel	79	8	M0	m0	NN
cord-300883-rws11uel	79	9	(	(	-LRB-
cord-300883-rws11uel	79	10	one	one	CD
cord-300883-rws11uel	79	11	-	-	HYPH
cord-300883-rws11uel	79	12	ratio	ratio	NN
cord-300883-rws11uel	79	13	)	)	-RRB-
cord-300883-rws11uel	79	14	,	,	,
cord-300883-rws11uel	79	15	M1a	M1a	NNP
cord-300883-rws11uel	79	16	(	(	-LRB-
cord-300883-rws11uel	79	17	nearly	nearly	RB
cord-300883-rws11uel	79	18	neutral	neutral	JJ
cord-300883-rws11uel	79	19	)	)	-RRB-
cord-300883-rws11uel	79	20	,	,	,
cord-300883-rws11uel	79	21	M2a	M2a	NNP
cord-300883-rws11uel	79	22	(	(	-LRB-
cord-300883-rws11uel	79	23	positive	positive	JJ
cord-300883-rws11uel	79	24	selection	selection	NN
cord-300883-rws11uel	79	25	)	)	-RRB-
cord-300883-rws11uel	79	26	,	,	,
cord-300883-rws11uel	79	27	M7	m7	NN
cord-300883-rws11uel	79	28	(	(	-LRB-
cord-300883-rws11uel	79	29	β	β	NN
cord-300883-rws11uel	79	30	distribution	distribution	NN
cord-300883-rws11uel	79	31	;	;	:
cord-300883-rws11uel	79	32	0	0	CD
cord-300883-rws11uel	79	33	≤	≤	NN
cord-300883-rws11uel	79	34	ω	ω	NN
cord-300883-rws11uel	79	35	≤	≤	NNP
cord-300883-rws11uel	79	36	1	1	CD
cord-300883-rws11uel	79	37	)	)	-RRB-
cord-300883-rws11uel	79	38	,	,	,
cord-300883-rws11uel	79	39	M8	M8	NNP
cord-300883-rws11uel	79	40	(	(	-LRB-
cord-300883-rws11uel	79	41	β	β	NN
cord-300883-rws11uel	79	42	+	+	CC
cord-300883-rws11uel	79	43	ω	ω	NN
cord-300883-rws11uel	79	44	>	>	XX
cord-300883-rws11uel	79	45	1	1	CD
cord-300883-rws11uel	79	46	:	:	:
cord-300883-rws11uel	79	47	continuous	continuous	JJ
cord-300883-rws11uel	79	48	)	)	-RRB-
cord-300883-rws11uel	80	1	(	(	-LRB-
cord-300883-rws11uel	80	2	Yang	Yang	NNP
cord-300883-rws11uel	80	3	et	et	NNP
cord-300883-rws11uel	80	4	al	al	NNP
cord-300883-rws11uel	80	5	.	.	NNP
cord-300883-rws11uel	80	6	,	,	,
cord-300883-rws11uel	80	7	2000	2000	CD
cord-300883-rws11uel	80	8	)	)	-RRB-
cord-300883-rws11uel	80	9	,	,	,
cord-300883-rws11uel	80	10	and	and	CC
cord-300883-rws11uel	80	11	M8a	M8a	NNP
cord-300883-rws11uel	81	1	(	(	-LRB-
cord-300883-rws11uel	81	2	β	β	NN
cord-300883-rws11uel	81	3	+	+	CC
cord-300883-rws11uel	81	4	ω	ω	NN
cord-300883-rws11uel	81	5	=	=	SYM
cord-300883-rws11uel	81	6	1	1	CD
cord-300883-rws11uel	81	7	)	)	-RRB-
cord-300883-rws11uel	82	1	(	(	-LRB-
cord-300883-rws11uel	82	2	Swanson	Swanson	NNP
cord-300883-rws11uel	82	3	et	et	NNP
cord-300883-rws11uel	82	4	al	al	NNP
cord-300883-rws11uel	82	5	.	.	NNP
cord-300883-rws11uel	82	6	,	,	,
cord-300883-rws11uel	82	7	2003	2003	CD
cord-300883-rws11uel	82	8	)	)	-RRB-
cord-300883-rws11uel	82	9	.	.	.
cord-300883-rws11uel	83	1	The	the	DT
cord-300883-rws11uel	83	2	M0	m0	NN
cord-300883-rws11uel	83	3	model	model	NN
cord-300883-rws11uel	83	4	estimates	estimate	VBZ
cord-300883-rws11uel	83	5	overall	overall	RB
cord-300883-rws11uel	83	6	ω	ω	CD
cord-300883-rws11uel	83	7	for	for	IN
cord-300883-rws11uel	83	8	the	the	DT
cord-300883-rws11uel	83	9	data	datum	NNS
cord-300883-rws11uel	83	10	.	.	.
cord-300883-rws11uel	84	1	The	the	DT
cord-300883-rws11uel	84	2	M1a	M1a	NNP
cord-300883-rws11uel	84	3	model	model	NN
cord-300883-rws11uel	84	4	estimates	estimate	VBZ
cord-300883-rws11uel	84	5	a	a	DT
cord-300883-rws11uel	84	6	single	single	JJ
cord-300883-rws11uel	84	7	parameter	parameter	NN
cord-300883-rws11uel	84	8	,	,	,
cord-300883-rws11uel	84	9	p	p	NN
cord-300883-rws11uel	84	10	0	0	CD
cord-300883-rws11uel	84	11	,	,	,
cord-300883-rws11uel	84	12	with	with	IN
cord-300883-rws11uel	84	13	ω	ω	NN
cord-300883-rws11uel	84	14	0	0	CD
cord-300883-rws11uel	84	15	=	=	SYM
cord-300883-rws11uel	84	16	0	0	CD
cord-300883-rws11uel	84	17	,	,	,
cord-300883-rws11uel	84	18	and	and	CC
cord-300883-rws11uel	84	19	the	the	DT
cord-300883-rws11uel	84	20	remaining	remain	VBG
cord-300883-rws11uel	84	21	sites	site	NNS
cord-300883-rws11uel	84	22	with	with	IN
cord-300883-rws11uel	84	23	frequency	frequency	NN
cord-300883-rws11uel	84	24	p	p	NN
cord-300883-rws11uel	84	25	1	1	CD
cord-300883-rws11uel	84	26	(	(	-LRB-
cord-300883-rws11uel	84	27	p	p	NN
cord-300883-rws11uel	84	28	1	1	CD
cord-300883-rws11uel	84	29	=	=	SYM
cord-300883-rws11uel	84	30	1	1	CD
cord-300883-rws11uel	84	31	−	−	NN
cord-300883-rws11uel	84	32	p	p	NN
cord-300883-rws11uel	84	33	0	0	CD
cord-300883-rws11uel	84	34	)	)	-RRB-
cord-300883-rws11uel	84	35	assuming	assume	VBG
cord-300883-rws11uel	84	36	ω	ω	NN
cord-300883-rws11uel	84	37	1	1	CD
cord-300883-rws11uel	84	38	=	=	SYM
cord-300883-rws11uel	84	39	1	1	CD
cord-300883-rws11uel	84	40	.	.	.
cord-300883-rws11uel	85	1	The	the	DT
cord-300883-rws11uel	85	2	M2a	M2a	NNP
cord-300883-rws11uel	85	3	model	model	NN
cord-300883-rws11uel	85	4	adds	add	VBZ
cord-300883-rws11uel	85	5	a	a	DT
cord-300883-rws11uel	85	6	class	class	NN
cord-300883-rws11uel	85	7	of	of	IN
cord-300883-rws11uel	85	8	positively	positively	RB
cord-300883-rws11uel	85	9	selected	select	VBN
cord-300883-rws11uel	85	10	sites	site	NNS
cord-300883-rws11uel	85	11	with	with	IN
cord-300883-rws11uel	85	12	frequency	frequency	NN
cord-300883-rws11uel	85	13	p	p	NN
cord-300883-rws11uel	85	14	2	2	CD
cord-300883-rws11uel	85	15	(	(	-LRB-
cord-300883-rws11uel	85	16	where	where	WRB
cord-300883-rws11uel	85	17	p	p	NN
cord-300883-rws11uel	85	18	2	2	CD
cord-300883-rws11uel	85	19	=	=	SYM
cord-300883-rws11uel	85	20	1	1	CD
cord-300883-rws11uel	85	21	−	−	NN
cord-300883-rws11uel	85	22	p	p	NN
cord-300883-rws11uel	85	23	1	1	CD
cord-300883-rws11uel	85	24	−	−	NN
cord-300883-rws11uel	85	25	p	p	NN
cord-300883-rws11uel	85	26	0	0	CD
cord-300883-rws11uel	85	27	)	)	-RRB-
cord-300883-rws11uel	85	28	with	with	IN
cord-300883-rws11uel	85	29	ω	ω	CD
cord-300883-rws11uel	85	30	2	2	CD
cord-300883-rws11uel	85	31	estimated	estimate	VBN
cord-300883-rws11uel	85	32	from	from	IN
cord-300883-rws11uel	85	33	the	the	DT
cord-300883-rws11uel	85	34	data	datum	NNS
cord-300883-rws11uel	85	35	.	.	.
cord-300883-rws11uel	86	1	In	in	IN
cord-300883-rws11uel	86	2	the	the	DT
cord-300883-rws11uel	86	3	M7	m7	NN
cord-300883-rws11uel	86	4	model	model	NN
cord-300883-rws11uel	86	5	,	,	,
cord-300883-rws11uel	86	6	ω	ω	NN
cord-300883-rws11uel	86	7	follows	follow	VBZ
cord-300883-rws11uel	86	8	a	a	DT
cord-300883-rws11uel	86	9	beta	beta	NN
cord-300883-rws11uel	86	10	distribution	distribution	NN
cord-300883-rws11uel	86	11	and	and	CC
cord-300883-rws11uel	86	12	is	be	VBZ
cord-300883-rws11uel	86	13	allowed	allow	VBN
cord-300883-rws11uel	86	14	to	to	TO
cord-300883-rws11uel	86	15	vary	vary	VB
cord-300883-rws11uel	86	16	between	between	IN
cord-300883-rws11uel	86	17	0	0	CD
cord-300883-rws11uel	86	18	and	and	CC
cord-300883-rws11uel	86	19	1	1	CD
cord-300883-rws11uel	86	20	,	,	,
cord-300883-rws11uel	86	21	and	and	CC
cord-300883-rws11uel	86	22	two	two	CD
cord-300883-rws11uel	86	23	parameters	parameter	NNS
cord-300883-rws11uel	86	24	(	(	-LRB-
cord-300883-rws11uel	86	25	p	p	NN
cord-300883-rws11uel	86	26	and	and	CC
cord-300883-rws11uel	86	27	q	q	NNP
cord-300883-rws11uel	86	28	)	)	-RRB-
cord-300883-rws11uel	86	29	of	of	IN
cord-300883-rws11uel	86	30	the	the	DT
cord-300883-rws11uel	86	31	beta	beta	NN
cord-300883-rws11uel	86	32	distribution	distribution	NN
cord-300883-rws11uel	86	33	are	be	VBP
cord-300883-rws11uel	86	34	estimated	estimate	VBN
cord-300883-rws11uel	86	35	from	from	IN
cord-300883-rws11uel	86	36	the	the	DT
cord-300883-rws11uel	86	37	data	datum	NNS
cord-300883-rws11uel	86	38	.	.	.
cord-300883-rws11uel	87	1	In	in	IN
cord-300883-rws11uel	87	2	the	the	DT
cord-300883-rws11uel	87	3	M8	M8	NNP
cord-300883-rws11uel	87	4	model	model	NN
cord-300883-rws11uel	87	5	,	,	,
cord-300883-rws11uel	87	6	a	a	DT
cord-300883-rws11uel	87	7	proportion	proportion	NN
cord-300883-rws11uel	87	8	,	,	,
cord-300883-rws11uel	87	9	p	p	NN
cord-300883-rws11uel	87	10	0	0	CD
cord-300883-rws11uel	87	11	,	,	,
cord-300883-rws11uel	87	12	of	of	IN
cord-300883-rws11uel	87	13	sites	site	NNS
cord-300883-rws11uel	87	14	have	have	VBP
cord-300883-rws11uel	87	15	ω	ω	NN
cord-300883-rws11uel	87	16	drawn	draw	VBN
cord-300883-rws11uel	87	17	from	from	IN
cord-300883-rws11uel	87	18	the	the	DT
cord-300883-rws11uel	87	19	beta	beta	NN
cord-300883-rws11uel	87	20	distribution	distribution	NN
cord-300883-rws11uel	87	21	and	and	CC
cord-300883-rws11uel	87	22	the	the	DT
cord-300883-rws11uel	87	23	remaining	remain	VBG
cord-300883-rws11uel	87	24	sites	site	NNS
cord-300883-rws11uel	87	25	with	with	IN
cord-300883-rws11uel	87	26	proportion	proportion	NN
cord-300883-rws11uel	87	27	p	p	NN
cord-300883-rws11uel	87	28	1	1	CD
cord-300883-rws11uel	87	29	are	be	VBP
cord-300883-rws11uel	87	30	positively	positively	RB
cord-300883-rws11uel	87	31	selected	select	VBN
cord-300883-rws11uel	87	32	(	(	-LRB-
cord-300883-rws11uel	87	33	ω	ω	NN
cord-300883-rws11uel	87	34	1	1	CD
cord-300883-rws11uel	87	35	>	>	SYM
cord-300883-rws11uel	87	36	1	1	CD
cord-300883-rws11uel	87	37	)	)	-RRB-
cord-300883-rws11uel	87	38	.	.	.
cord-300883-rws11uel	88	1	The	the	DT
cord-300883-rws11uel	88	2	LRTs	lrt	NNS
cord-300883-rws11uel	88	3	between	between	IN
cord-300883-rws11uel	88	4	nested	nested	JJ
cord-300883-rws11uel	88	5	models	model	NNS
cord-300883-rws11uel	88	6	were	be	VBD
cord-300883-rws11uel	88	7	conducted	conduct	VBN
cord-300883-rws11uel	88	8	by	by	IN
cord-300883-rws11uel	88	9	comparing	compare	VBG
cord-300883-rws11uel	88	10	twice	twice	PDT
cord-300883-rws11uel	88	11	the	the	DT
cord-300883-rws11uel	88	12	difference	difference	NN
cord-300883-rws11uel	88	13	in	in	IN
cord-300883-rws11uel	88	14	log	log	NN
cord-300883-rws11uel	88	15	-	-	HYPH
cord-300883-rws11uel	88	16	likelihood	likelihood	NN
cord-300883-rws11uel	88	17	values	value	NNS
cord-300883-rws11uel	88	18	(	(	-LRB-
cord-300883-rws11uel	88	19	2ln	2ln	NNP
cord-300883-rws11uel	88	20	l	l	NNP
cord-300883-rws11uel	88	21	)	)	-RRB-
cord-300883-rws11uel	88	22	against	against	IN
cord-300883-rws11uel	88	23	a	a	DT
cord-300883-rws11uel	88	24	χ	χ	CD
cord-300883-rws11uel	88	25	2	2	CD
cord-300883-rws11uel	88	26	-distribution	-distribution	NN
cord-300883-rws11uel	88	27	with	with	IN
cord-300883-rws11uel	88	28	degrees	degree	NNS
cord-300883-rws11uel	88	29	of	of	IN
cord-300883-rws11uel	88	30	freedom	freedom	NN
cord-300883-rws11uel	88	31	equal	equal	JJ
cord-300883-rws11uel	88	32	to	to	IN
cord-300883-rws11uel	88	33	the	the	DT
cord-300883-rws11uel	88	34	difference	difference	NN
cord-300883-rws11uel	88	35	in	in	IN
cord-300883-rws11uel	88	36	the	the	DT
cord-300883-rws11uel	88	37	number	number	NN
cord-300883-rws11uel	88	38	of	of	IN
cord-300883-rws11uel	88	39	parameters	parameter	NNS
cord-300883-rws11uel	88	40	between	between	IN
cord-300883-rws11uel	88	41	models	model	NNS
cord-300883-rws11uel	88	42	(	(	-LRB-
cord-300883-rws11uel	88	43	Yang	Yang	NNP
cord-300883-rws11uel	88	44	,	,	,
cord-300883-rws11uel	88	45	1997	1997	CD
cord-300883-rws11uel	88	46	)	)	-RRB-
cord-300883-rws11uel	88	47	.	.	.
cord-300883-rws11uel	89	1	Three	three	CD
cord-300883-rws11uel	89	2	LRTs	lrt	NNS
cord-300883-rws11uel	89	3	were	be	VBD
cord-300883-rws11uel	89	4	conducted	conduct	VBN
cord-300883-rws11uel	89	5	.	.	.
cord-300883-rws11uel	90	1	The	the	DT
cord-300883-rws11uel	90	2	first	first	JJ
cord-300883-rws11uel	90	3	comparison	comparison	NN
cord-300883-rws11uel	90	4	was	be	VBD
cord-300883-rws11uel	90	5	made	make	VBN
cord-300883-rws11uel	90	6	between	between	IN
cord-300883-rws11uel	90	7	M1a	M1a	NNP
cord-300883-rws11uel	90	8	,	,	,
cord-300883-rws11uel	90	9	which	which	WDT
cord-300883-rws11uel	90	10	allows	allow	VBZ
cord-300883-rws11uel	90	11	for	for	IN
cord-300883-rws11uel	90	12	two	two	CD
cord-300883-rws11uel	90	13	site	site	NN
cord-300883-rws11uel	90	14	classes	class	NNS
cord-300883-rws11uel	90	15	(	(	-LRB-
cord-300883-rws11uel	90	16	0	0	NFP
cord-300883-rws11uel	90	17	<	<	XX
cord-300883-rws11uel	90	18	ω	ω	NN
cord-300883-rws11uel	90	19	<	<	XX
cord-300883-rws11uel	90	20	1	1	CD
cord-300883-rws11uel	90	21	,	,	,
cord-300883-rws11uel	90	22	ω	ω	NN
cord-300883-rws11uel	90	23	=	=	SYM
cord-300883-rws11uel	90	24	1	1	CD
cord-300883-rws11uel	90	25	)	)	-RRB-
cord-300883-rws11uel	90	26	,	,	,
cord-300883-rws11uel	90	27	and	and	CC
cord-300883-rws11uel	90	28	M2a	M2a	NNP
cord-300883-rws11uel	90	29	,	,	,
cord-300883-rws11uel	90	30	which	which	WDT
cord-300883-rws11uel	90	31	allows	allow	VBZ
cord-300883-rws11uel	90	32	three	three	CD
cord-300883-rws11uel	90	33	site	site	NN
cord-300883-rws11uel	90	34	classes	class	NNS
cord-300883-rws11uel	90	35	(	(	-LRB-
cord-300883-rws11uel	90	36	0	0	NFP
cord-300883-rws11uel	90	37	<	<	XX
cord-300883-rws11uel	90	38	ω	ω	NN
cord-300883-rws11uel	90	39	<	<	XX
cord-300883-rws11uel	90	40	1	1	CD
cord-300883-rws11uel	90	41	,	,	,
cord-300883-rws11uel	90	42	ω	ω	NN
cord-300883-rws11uel	90	43	=	=	SYM
cord-300883-rws11uel	90	44	1	1	CD
cord-300883-rws11uel	90	45	or	or	CC
cord-300883-rws11uel	90	46	ω	ω	NN
cord-300883-rws11uel	90	47	>	>	XX
cord-300883-rws11uel	90	48	1	1	CD
cord-300883-rws11uel	90	49	)	)	-RRB-
cord-300883-rws11uel	90	50	.	.	.
cord-300883-rws11uel	91	1	The	the	DT
cord-300883-rws11uel	91	2	second	second	JJ
cord-300883-rws11uel	91	3	comparison	comparison	NN
cord-300883-rws11uel	91	4	was	be	VBD
cord-300883-rws11uel	91	5	between	between	IN
cord-300883-rws11uel	91	6	M7	m7	NN
cord-300883-rws11uel	91	7	and	and	CC
cord-300883-rws11uel	91	8	M8	m8	NN
cord-300883-rws11uel	91	9	,	,	,
cord-300883-rws11uel	91	10	and	and	CC
cord-300883-rws11uel	91	11	the	the	DT
cord-300883-rws11uel	91	12	last	last	JJ
cord-300883-rws11uel	91	13	comparison	comparison	NN
cord-300883-rws11uel	91	14	was	be	VBD
cord-300883-rws11uel	91	15	between	between	IN
cord-300883-rws11uel	91	16	M8	m8	NN
cord-300883-rws11uel	91	17	and	and	CC
cord-300883-rws11uel	91	18	M8a	M8a	NNP
cord-300883-rws11uel	91	19	,	,	,
cord-300883-rws11uel	91	20	in	in	IN
cord-300883-rws11uel	91	21	which	which	WDT
cord-300883-rws11uel	91	22	ω	ω	NN
cord-300883-rws11uel	91	23	for	for	IN
cord-300883-rws11uel	91	24	 	 	_SP
cord-300883-rws11uel	91	25	hMPV13	hMPV13	NNP
cord-300883-rws11uel	91	26	-	-	HYPH
cord-300883-rws11uel	91	27	M8a	M8a	NNP
cord-300883-rws11uel	91	28	was	be	VBD
cord-300883-rws11uel	91	29	constrained	constrain	VBN
cord-300883-rws11uel	91	30	to	to	IN
cord-300883-rws11uel	91	31	1	1	CD
cord-300883-rws11uel	91	32	.	.	.
cord-300883-rws11uel	92	1	In	in	IN
cord-300883-rws11uel	92	2	all	all	DT
cord-300883-rws11uel	92	3	LRTs	lrt	NNS
cord-300883-rws11uel	92	4	good	good	JJ
cord-300883-rws11uel	92	5	evidence	evidence	NN
cord-300883-rws11uel	92	6	for	for	IN
cord-300883-rws11uel	92	7	positive	positive	JJ
cord-300883-rws11uel	92	8	selection	selection	NN
cord-300883-rws11uel	92	9	is	be	VBZ
cord-300883-rws11uel	92	10	found	find	VBN
cord-300883-rws11uel	92	11	if	if	IN
cord-300883-rws11uel	92	12	the	the	DT
cord-300883-rws11uel	92	13	LRT	LRT	NNP
cord-300883-rws11uel	92	14	indicates	indicate	VBZ
cord-300883-rws11uel	92	15	that	that	IN
cord-300883-rws11uel	92	16	models	model	NNS
cord-300883-rws11uel	92	17	that	that	WDT
cord-300883-rws11uel	92	18	allow	allow	VBP
cord-300883-rws11uel	92	19	for	for	IN
cord-300883-rws11uel	92	20	selection	selection	NN
cord-300883-rws11uel	92	21	(	(	-LRB-
cord-300883-rws11uel	92	22	i.e.	i.e.	FW
cord-300883-rws11uel	92	23	M2a	M2a	NNP
cord-300883-rws11uel	92	24	and	and	CC
cord-300883-rws11uel	92	25	M8	m8	NN
cord-300883-rws11uel	92	26	;	;	:
cord-300883-rws11uel	92	27	alternative	alternative	JJ
cord-300883-rws11uel	92	28	models	model	NNS
cord-300883-rws11uel	92	29	)	)	-RRB-
cord-300883-rws11uel	92	30	are	be	VBP
cord-300883-rws11uel	92	31	significantly	significantly	RB
cord-300883-rws11uel	92	32	better	well	JJR
cord-300883-rws11uel	92	33	than	than	IN
cord-300883-rws11uel	92	34	their	-PRON-	PRP$
cord-300883-rws11uel	92	35	respective	respective	JJ
cord-300883-rws11uel	92	36	null	null	JJ
cord-300883-rws11uel	92	37	models	model	NNS
cord-300883-rws11uel	92	38	(	(	-LRB-
cord-300883-rws11uel	92	39	M1a	M1a	NNP
cord-300883-rws11uel	92	40	,	,	,
cord-300883-rws11uel	92	41	M7	M7	NNP
cord-300883-rws11uel	92	42	and	and	CC
cord-300883-rws11uel	92	43	M8a	M8a	NNP
cord-300883-rws11uel	92	44	)	)	-RRB-
cord-300883-rws11uel	93	1	(	(	-LRB-
cord-300883-rws11uel	93	2	Yang	Yang	NNP
cord-300883-rws11uel	93	3	,	,	,
cord-300883-rws11uel	93	4	1997	1997	CD
cord-300883-rws11uel	93	5	)	)	-RRB-
cord-300883-rws11uel	93	6	.	.	.
cord-300883-rws11uel	94	1	Posterior	posterior	JJ
cord-300883-rws11uel	94	2	probabilities	probability	NNS
cord-300883-rws11uel	94	3	of	of	IN
cord-300883-rws11uel	94	4	the	the	DT
cord-300883-rws11uel	94	5	inferred	infer	VBN
cord-300883-rws11uel	94	6	positively	positively	RB
cord-300883-rws11uel	94	7	selected	select	VBN
cord-300883-rws11uel	94	8	sites	site	NNS
cord-300883-rws11uel	94	9	were	be	VBD
cord-300883-rws11uel	94	10	estimated	estimate	VBN
cord-300883-rws11uel	94	11	by	by	IN
cord-300883-rws11uel	94	12	the	the	DT
cord-300883-rws11uel	94	13	Bayes	Bayes	NNP
cord-300883-rws11uel	94	14	empirical	empirical	JJ
cord-300883-rws11uel	94	15	Bayes	Bayes	NNP
cord-300883-rws11uel	94	16	(	(	-LRB-
cord-300883-rws11uel	94	17	BEB	BEB	NNP
cord-300883-rws11uel	94	18	)	)	-RRB-
cord-300883-rws11uel	94	19	approach	approach	NN
cord-300883-rws11uel	94	20	that	that	WDT
cord-300883-rws11uel	94	21	takes	take	VBZ
cord-300883-rws11uel	94	22	sampling	sampling	NN
cord-300883-rws11uel	94	23	errors	error	NNS
cord-300883-rws11uel	94	24	into	into	IN
cord-300883-rws11uel	94	25	account	account	NN
cord-300883-rws11uel	95	1	(	(	-LRB-
cord-300883-rws11uel	95	2	Yang	Yang	NNP
cord-300883-rws11uel	95	3	et	et	NNP
cord-300883-rws11uel	95	4	al	al	NNP
cord-300883-rws11uel	95	5	.	.	NNP
cord-300883-rws11uel	95	6	,	,	,
cord-300883-rws11uel	95	7	2005	2005	CD
cord-300883-rws11uel	95	8	)	)	-RRB-
cord-300883-rws11uel	95	9	.	.	.
cord-300883-rws11uel	96	1	Consistent	consistent	JJ
cord-300883-rws11uel	96	2	with	with	IN
cord-300883-rws11uel	96	3	earlier	early	JJR
cord-300883-rws11uel	96	4	studies	study	NNS
cord-300883-rws11uel	96	5	(	(	-LRB-
cord-300883-rws11uel	96	6	Peret	Peret	NNP
cord-300883-rws11uel	96	7	et	et	NNP
cord-300883-rws11uel	96	8	al	al	NNP
cord-300883-rws11uel	96	9	.	.	NNP
cord-300883-rws11uel	96	10	,	,	,
cord-300883-rws11uel	96	11	2004	2004	CD
cord-300883-rws11uel	96	12	)	)	-RRB-
cord-300883-rws11uel	96	13	,	,	,
cord-300883-rws11uel	96	14	G	g	NN
cord-300883-rws11uel	96	15	-	-	HYPH
cord-300883-rws11uel	96	16	protein	protein	NN
cord-300883-rws11uel	96	17	based	base	VBN
cord-300883-rws11uel	96	18	phylogeny	phylogeny	NN
cord-300883-rws11uel	96	19	in	in	IN
cord-300883-rws11uel	96	20	the	the	DT
cord-300883-rws11uel	96	21	present	present	JJ
cord-300883-rws11uel	96	22	study	study	NN
cord-300883-rws11uel	96	23	has	have	VBZ
cord-300883-rws11uel	96	24	also	also	RB
cord-300883-rws11uel	96	25	revealed	reveal	VBN
cord-300883-rws11uel	96	26	the	the	DT
cord-300883-rws11uel	96	27	existence	existence	NN
cord-300883-rws11uel	96	28	of	of	IN
cord-300883-rws11uel	96	29	multiple	multiple	JJ
cord-300883-rws11uel	96	30	lineages	lineage	NNS
cord-300883-rws11uel	96	31	of	of	IN
cord-300883-rws11uel	96	32	this	this	DT
cord-300883-rws11uel	96	33	virus	virus	NN
cord-300883-rws11uel	97	1	(	(	-LRB-
cord-300883-rws11uel	97	2	Fig	Fig	NNP
cord-300883-rws11uel	97	3	.	.	NNP
cord-300883-rws11uel	97	4	1	1	CD
cord-300883-rws11uel	97	5	)	)	-RRB-
cord-300883-rws11uel	97	6	.	.	.
cord-300883-rws11uel	98	1	All	all	DT
cord-300883-rws11uel	98	2	four	four	CD
cord-300883-rws11uel	98	3	lineages	lineage	NNS
cord-300883-rws11uel	98	4	showed	show	VBD
cord-300883-rws11uel	98	5	some	some	DT
cord-300883-rws11uel	98	6	degree	degree	NN
cord-300883-rws11uel	98	7	of	of	IN
cord-300883-rws11uel	98	8	spatial	spatial	JJ
cord-300883-rws11uel	98	9	structure	structure	NN
cord-300883-rws11uel	98	10	;	;	:
cord-300883-rws11uel	98	11	however	however	RB
cord-300883-rws11uel	98	12	,	,	,
cord-300883-rws11uel	98	13	few	few	JJ
cord-300883-rws11uel	98	14	strains	strain	NNS
cord-300883-rws11uel	98	15	in	in	IN
cord-300883-rws11uel	98	16	each	each	DT
cord-300883-rws11uel	98	17	lineage	lineage	NN
cord-300883-rws11uel	98	18	did	do	VBD
cord-300883-rws11uel	98	19	not	not	RB
cord-300883-rws11uel	98	20	show	show	VB
cord-300883-rws11uel	98	21	any	any	DT
cord-300883-rws11uel	98	22	spatial	spatial	JJ
cord-300883-rws11uel	98	23	structure	structure	NN
cord-300883-rws11uel	98	24	,	,	,
cord-300883-rws11uel	98	25	indicating	indicate	VBG
cord-300883-rws11uel	98	26	extensive	extensive	JJ
cord-300883-rws11uel	98	27	viral	viral	JJ
cord-300883-rws11uel	98	28	gene	gene	NN
cord-300883-rws11uel	98	29	flow	flow	NN
cord-300883-rws11uel	98	30	across	across	IN
cord-300883-rws11uel	98	31	the	the	DT
cord-300883-rws11uel	98	32	regions	region	NNS
cord-300883-rws11uel	98	33	in	in	IN
cord-300883-rws11uel	98	34	a	a	DT
cord-300883-rws11uel	98	35	given	give	VBN
cord-300883-rws11uel	98	36	epidemic	epidemic	NN
cord-300883-rws11uel	98	37	season	season	NN
cord-300883-rws11uel	98	38	.	.	.
cord-300883-rws11uel	99	1	Relatively	relatively	RB
cord-300883-rws11uel	99	2	weak	weak	JJ
cord-300883-rws11uel	99	3	temporal	temporal	JJ
cord-300883-rws11uel	99	4	structure	structure	NN
cord-300883-rws11uel	99	5	across	across	IN
cord-300883-rws11uel	99	6	the	the	DT
cord-300883-rws11uel	99	7	regions	region	NNS
cord-300883-rws11uel	99	8	further	further	RB
cord-300883-rws11uel	99	9	suggested	suggest	VBD
cord-300883-rws11uel	99	10	that	that	IN
cord-300883-rws11uel	99	11	either	either	CC
cord-300883-rws11uel	99	12	certain	certain	JJ
cord-300883-rws11uel	99	13	strains	strain	NNS
cord-300883-rws11uel	99	14	can	can	MD
cord-300883-rws11uel	99	15	remain	remain	VB
cord-300883-rws11uel	99	16	stable	stable	JJ
cord-300883-rws11uel	99	17	for	for	IN
cord-300883-rws11uel	99	18	more	more	JJR
cord-300883-rws11uel	99	19	than	than	IN
cord-300883-rws11uel	99	20	one	one	CD
cord-300883-rws11uel	99	21	epidemic	epidemic	NN
cord-300883-rws11uel	99	22	season	season	NN
cord-300883-rws11uel	99	23	(	(	-LRB-
cord-300883-rws11uel	99	24	e.g.	e.g.	RB
cord-300883-rws11uel	99	25	,	,	,
cord-300883-rws11uel	99	26	HRSV	HRSV	NNP
cord-300883-rws11uel	99	27	,	,	,
cord-300883-rws11uel	99	28	Zlateva	Zlateva	NNP
cord-300883-rws11uel	99	29	et	et	FW
cord-300883-rws11uel	99	30	al	al	NNP
cord-300883-rws11uel	99	31	.	.	NNP
cord-300883-rws11uel	99	32	,	,	,
cord-300883-rws11uel	99	33	2004	2004	CD
cord-300883-rws11uel	100	1	Zlateva	Zlateva	NNP
cord-300883-rws11uel	100	2	et	et	FW
cord-300883-rws11uel	100	3	al	al	NNP
cord-300883-rws11uel	100	4	.	.	NNP
cord-300883-rws11uel	100	5	,	,	,
cord-300883-rws11uel	100	6	,	,	,
cord-300883-rws11uel	100	7	2005	2005	CD
cord-300883-rws11uel	100	8	,	,	,
cord-300883-rws11uel	100	9	or	or	CC
cord-300883-rws11uel	100	10	mutations	mutation	NNS
cord-300883-rws11uel	100	11	might	may	MD
cord-300883-rws11uel	100	12	not	not	RB
cord-300883-rws11uel	100	13	have	have	VB
cord-300883-rws11uel	100	14	occurred	occur	VBN
cord-300883-rws11uel	100	15	in	in	IN
cord-300883-rws11uel	100	16	a	a	DT
cord-300883-rws11uel	100	17	linear	linear	JJ
cord-300883-rws11uel	100	18	fashion	fashion	NN
cord-300883-rws11uel	100	19	with	with	IN
cord-300883-rws11uel	100	20	the	the	DT
cord-300883-rws11uel	100	21	preservation	preservation	NN
cord-300883-rws11uel	100	22	of	of	IN
cord-300883-rws11uel	100	23	changes	change	NNS
cord-300883-rws11uel	100	24	in	in	IN
cord-300883-rws11uel	100	25	the	the	DT
cord-300883-rws11uel	100	26	circulating	circulate	VBG
cord-300883-rws11uel	100	27	viral	viral	JJ
cord-300883-rws11uel	100	28	strains	strain	NNS
cord-300883-rws11uel	100	29	.	.	.
cord-300883-rws11uel	101	1	Thus	thus	RB
cord-300883-rws11uel	101	2	,	,	,
cord-300883-rws11uel	101	3	virus	virus	NN
cord-300883-rws11uel	101	4	genotypes	genotype	NNS
cord-300883-rws11uel	101	5	would	would	MD
cord-300883-rws11uel	101	6	frequently	frequently	RB
cord-300883-rws11uel	101	7	appear	appear	VB
cord-300883-rws11uel	101	8	and	and	CC
cord-300883-rws11uel	101	9	disappear	disappear	VB
cord-300883-rws11uel	101	10	along	along	IN
cord-300883-rws11uel	101	11	with	with	IN
cord-300883-rws11uel	101	12	new	new	JJ
cord-300883-rws11uel	101	13	mutations	mutation	NNS
cord-300883-rws11uel	101	14	in	in	IN
cord-300883-rws11uel	101	15	the	the	DT
cord-300883-rws11uel	101	16	populations	population	NNS
cord-300883-rws11uel	101	17	.	.	.
cord-300883-rws11uel	102	1	However	however	RB
cord-300883-rws11uel	102	2	,	,	,
cord-300883-rws11uel	102	3	HRSV	HRSV	NNP
cord-300883-rws11uel	102	4	(	(	-LRB-
cord-300883-rws11uel	102	5	Zlateva	Zlateva	NNP
cord-300883-rws11uel	102	6	et	et	FW
cord-300883-rws11uel	102	7	al	al	NNP
cord-300883-rws11uel	102	8	.	.	NNP
cord-300883-rws11uel	102	9	,	,	,
cord-300883-rws11uel	102	10	2004	2004	CD
cord-300883-rws11uel	102	11	(	(	-LRB-
cord-300883-rws11uel	102	12	Zlateva	Zlateva	NNP
cord-300883-rws11uel	102	13	et	et	FW
cord-300883-rws11uel	102	14	al	al	NNP
cord-300883-rws11uel	102	15	.	.	NNP
cord-300883-rws11uel	102	16	,	,	,
cord-300883-rws11uel	102	17	,	,	,
cord-300883-rws11uel	102	18	2005	2005	CD
cord-300883-rws11uel	102	19	showed	show	VBD
cord-300883-rws11uel	102	20	a	a	DT
cord-300883-rws11uel	102	21	strong	strong	JJ
cord-300883-rws11uel	102	22	correlation	correlation	NN
cord-300883-rws11uel	102	23	between	between	IN
cord-300883-rws11uel	102	24	the	the	DT
cord-300883-rws11uel	102	25	accumulation	accumulation	NN
cord-300883-rws11uel	102	26	of	of	IN
cord-300883-rws11uel	102	27	genetic	genetic	JJ
cord-300883-rws11uel	102	28	divergence	divergence	NN
cord-300883-rws11uel	102	29	and	and	CC
cord-300883-rws11uel	102	30	the	the	DT
cord-300883-rws11uel	102	31	isolation	isolation	NN
cord-300883-rws11uel	102	32	date	date	NN
cord-300883-rws11uel	102	33	of	of	IN
cord-300883-rws11uel	102	34	the	the	DT
cord-300883-rws11uel	102	35	sequences	sequence	NNS
cord-300883-rws11uel	102	36	.	.	.
cord-300883-rws11uel	103	1	Based	base	VBN
cord-300883-rws11uel	103	2	on	on	IN
cord-300883-rws11uel	103	3	the	the	DT
cord-300883-rws11uel	103	4	relaxed	relaxed	JJ
cord-300883-rws11uel	103	5	clock	clock	NN
cord-300883-rws11uel	103	6	assumption	assumption	NN
cord-300883-rws11uel	103	7	,	,	,
cord-300883-rws11uel	103	8	the	the	DT
cord-300883-rws11uel	103	9	evolutionary	evolutionary	JJ
cord-300883-rws11uel	103	10	rate	rate	NN
cord-300883-rws11uel	103	11	of	of	IN
cord-300883-rws11uel	103	12	each	each	DT
cord-300883-rws11uel	103	13	major	major	JJ
cord-300883-rws11uel	103	14	lineage	lineage	NN
cord-300883-rws11uel	103	15	of	of	IN
cord-300883-rws11uel	103	16	hMPVs	hMPVs	NNP
cord-300883-rws11uel	103	17	(	(	-LRB-
cord-300883-rws11uel	103	18	1	1	CD
cord-300883-rws11uel	103	19	and	and	CC
cord-300883-rws11uel	103	20	2	2	CD
cord-300883-rws11uel	103	21	;	;	:
cord-300883-rws11uel	103	22	Table	table	NN
cord-300883-rws11uel	103	23	2	2	CD
cord-300883-rws11uel	103	24	)	)	-RRB-
cord-300883-rws11uel	103	25	are	be	VBP
cord-300883-rws11uel	103	26	5.18	5.18	CD
cord-300883-rws11uel	103	27	×	×	NN
cord-300883-rws11uel	103	28	10	10	CD
cord-300883-rws11uel	103	29	−3	−3	NN
cord-300883-rws11uel	103	30	and	and	CC
cord-300883-rws11uel	103	31	6.49	6.49	CD
cord-300883-rws11uel	103	32	×	×	NN
cord-300883-rws11uel	103	33	10	10	CD
cord-300883-rws11uel	104	1	−3	−3	NNP
cord-300883-rws11uel	104	2	substitutions	substitution	NNS
cord-300883-rws11uel	104	3	/	/	SYM
cord-300883-rws11uel	104	4	site	site	NN
cord-300883-rws11uel	104	5	/	/	SYM
cord-300883-rws11uel	104	6	year	year	NN
cord-300883-rws11uel	104	7	,	,	,
cord-300883-rws11uel	104	8	respectively	respectively	RB
cord-300883-rws11uel	104	9	.	.	.
cord-300883-rws11uel	105	1	Although	although	IN
cord-300883-rws11uel	105	2	these	these	DT
cord-300883-rws11uel	105	3	rates	rate	NNS
cord-300883-rws11uel	105	4	are	be	VBP
cord-300883-rws11uel	105	5	compatible	compatible	JJ
cord-300883-rws11uel	105	6	with	with	IN
cord-300883-rws11uel	105	7	the	the	DT
cord-300883-rws11uel	105	8	substitution	substitution	NN
cord-300883-rws11uel	105	9	rates	rate	NNS
cord-300883-rws11uel	105	10	reported	report	VBN
cord-300883-rws11uel	105	11	for	for	IN
cord-300883-rws11uel	105	12	influenza	influenza	NN
cord-300883-rws11uel	105	13	viruses	virus	NNS
cord-300883-rws11uel	105	14	(	(	-LRB-
cord-300883-rws11uel	105	15	Chen	Chen	NNP
cord-300883-rws11uel	105	16	and	and	CC
cord-300883-rws11uel	105	17	Holmes	Holmes	NNP
cord-300883-rws11uel	105	18	,	,	,
cord-300883-rws11uel	105	19	2006	2006	CD
cord-300883-rws11uel	105	20	)	)	-RRB-
cord-300883-rws11uel	105	21	,	,	,
cord-300883-rws11uel	105	22	these	these	DT
cord-300883-rws11uel	105	23	rates	rate	NNS
cord-300883-rws11uel	105	24	are	be	VBP
cord-300883-rws11uel	105	25	higher	high	JJR
cord-300883-rws11uel	105	26	than	than	IN
cord-300883-rws11uel	105	27	the	the	DT
cord-300883-rws11uel	105	28	estimates	estimate	NNS
cord-300883-rws11uel	105	29	of	of	IN
cord-300883-rws11uel	105	30	HRSV	HRSV	NNP
cord-300883-rws11uel	105	31	(	(	-LRB-
cord-300883-rws11uel	105	32	Matheson	Matheson	NNP
cord-300883-rws11uel	105	33	et	et	NNP
cord-300883-rws11uel	105	34	al	al	NNP
cord-300883-rws11uel	105	35	.	.	NNP
cord-300883-rws11uel	105	36	,	,	,
cord-300883-rws11uel	105	37	2006	2006	CD
cord-300883-rws11uel	105	38	)	)	-RRB-
cord-300883-rws11uel	105	39	and	and	CC
cord-300883-rws11uel	105	40	other	other	JJ
cord-300883-rws11uel	105	41	paramyxoviruses	paramyxovirus	NNS
cord-300883-rws11uel	105	42	(	(	-LRB-
cord-300883-rws11uel	105	43	e.g.	e.g.	RB
cord-300883-rws11uel	105	44	,	,	,
cord-300883-rws11uel	105	45	measles	measle	NNS
cord-300883-rws11uel	105	46	:	:	:
cord-300883-rws11uel	105	47	Woelk	Woelk	NNP
cord-300883-rws11uel	105	48	et	et	NNP
cord-300883-rws11uel	105	49	al	al	NNP
cord-300883-rws11uel	105	50	.	.	NNP
cord-300883-rws11uel	105	51	,	,	,
cord-300883-rws11uel	105	52	2002	2002	CD
cord-300883-rws11uel	105	53	)	)	-RRB-
cord-300883-rws11uel	105	54	.	.	.
cord-300883-rws11uel	106	1	These	these	DT
cord-300883-rws11uel	106	2	discrepancies	discrepancy	NNS
cord-300883-rws11uel	106	3	in	in	IN
cord-300883-rws11uel	106	4	the	the	DT
cord-300883-rws11uel	106	5	evolutionary	evolutionary	JJ
cord-300883-rws11uel	106	6	rates	rate	NNS
cord-300883-rws11uel	106	7	could	could	MD
cord-300883-rws11uel	106	8	be	be	VB
cord-300883-rws11uel	106	9	associated	associate	VBN
cord-300883-rws11uel	106	10	with	with	IN
cord-300883-rws11uel	106	11	the	the	DT
cord-300883-rws11uel	106	12	differential	differential	JJ
cord-300883-rws11uel	106	13	selective	selective	JJ
cord-300883-rws11uel	106	14	pressures	pressure	NNS
cord-300883-rws11uel	106	15	targeting	target	VBG
cord-300883-rws11uel	106	16	different	different	JJ
cord-300883-rws11uel	106	17	genomic	genomic	JJ
cord-300883-rws11uel	106	18	regions	region	NNS
cord-300883-rws11uel	106	19	.	.	.
cord-300883-rws11uel	107	1	For	for	IN
cord-300883-rws11uel	107	2	example	example	NN
cord-300883-rws11uel	107	3	,	,	,
cord-300883-rws11uel	107	4	the	the	DT
cord-300883-rws11uel	107	5	presence	presence	NN
cord-300883-rws11uel	107	6	of	of	IN
cord-300883-rws11uel	107	7	a	a	DT
cord-300883-rws11uel	107	8	greater	great	JJR
cord-300883-rws11uel	107	9	number	number	NN
cord-300883-rws11uel	107	10	of	of	IN
cord-300883-rws11uel	107	11	adaptively	adaptively	RB
cord-300883-rws11uel	107	12	evolved	evolve	VBN
cord-300883-rws11uel	107	13	amino	amino	NN
cord-300883-rws11uel	107	14	acid	acid	NN
cord-300883-rws11uel	107	15	sites	site	NNS
cord-300883-rws11uel	107	16	in	in	IN
cord-300883-rws11uel	107	17	the	the	DT
cord-300883-rws11uel	107	18	gene	gene	NN
cord-300883-rws11uel	107	19	can	can	MD
cord-300883-rws11uel	107	20	cause	cause	VB
cord-300883-rws11uel	107	21	an	an	DT
cord-300883-rws11uel	107	22	accelerated	accelerate	VBN
cord-300883-rws11uel	107	23	rate	rate	NN
cord-300883-rws11uel	107	24	of	of	IN
cord-300883-rws11uel	107	25	evolution	evolution	NN
cord-300883-rws11uel	107	26	.	.	.
cord-300883-rws11uel	108	1	As	as	IN
cord-300883-rws11uel	108	2	a	a	DT
cord-300883-rws11uel	108	3	consequence	consequence	NN
cord-300883-rws11uel	108	4	,	,	,
cord-300883-rws11uel	108	5	the	the	DT
cord-300883-rws11uel	108	6	overall	overall	JJ
cord-300883-rws11uel	108	7	evolutionary	evolutionary	JJ
cord-300883-rws11uel	108	8	rate	rate	NN
cord-300883-rws11uel	108	9	is	be	VBZ
cord-300883-rws11uel	108	10	expected	expect	VBN
cord-300883-rws11uel	108	11	to	to	TO
cord-300883-rws11uel	108	12	be	be	VB
cord-300883-rws11uel	108	13	higher	high	JJR
cord-300883-rws11uel	108	14	.	.	.
cord-300883-rws11uel	109	1	Both	both	DT
cord-300883-rws11uel	109	2	major	major	JJ
cord-300883-rws11uel	109	3	lineages	lineage	NNS
cord-300883-rws11uel	109	4	of	of	IN
cord-300883-rws11uel	109	5	hMPVs	hMPVs	NNPS
cord-300883-rws11uel	109	6	showed	show	VBD
cord-300883-rws11uel	109	7	interesting	interesting	JJ
cord-300883-rws11uel	109	8	population	population	NN
cord-300883-rws11uel	109	9	dynamics	dynamic	NNS
cord-300883-rws11uel	109	10	(	(	-LRB-
cord-300883-rws11uel	109	11	Fig	fig	NN
cord-300883-rws11uel	109	12	.	.	NNP
cord-300883-rws11uel	109	13	2	2	CD
cord-300883-rws11uel	109	14	)	)	-RRB-
cord-300883-rws11uel	109	15	.	.	.
cord-300883-rws11uel	110	1	The	the	DT
cord-300883-rws11uel	110	2	times	time	NNS
cord-300883-rws11uel	110	3	to	to	IN
cord-300883-rws11uel	110	4	the	the	DT
cord-300883-rws11uel	110	5	most	most	RBS
cord-300883-rws11uel	110	6	recent	recent	JJ
cord-300883-rws11uel	110	7	common	common	JJ
cord-300883-rws11uel	110	8	ancestor	ancestor	NN
cord-300883-rws11uel	110	9	for	for	IN
cord-300883-rws11uel	110	10	lineage	lineage	NN
cord-300883-rws11uel	110	11	1	1	CD
cord-300883-rws11uel	110	12	and	and	CC
cord-300883-rws11uel	110	13	2	2	CD
cord-300883-rws11uel	110	14	are	be	VBP
cord-300883-rws11uel	110	15	49.452	49.452	CD
cord-300883-rws11uel	110	16	(	(	-LRB-
cord-300883-rws11uel	110	17	29.08	29.08	CD
cord-300883-rws11uel	110	18	-	-	SYM
cord-300883-rws11uel	110	19	70.8	70.8	CD
cord-300883-rws11uel	110	20	)	)	-RRB-
cord-300883-rws11uel	110	21	and	and	CC
cord-300883-rws11uel	110	22	26.091	26.091	CD
cord-300883-rws11uel	110	23	(	(	-LRB-
cord-300883-rws11uel	110	24	21	21	CD
cord-300883-rws11uel	110	25	-	-	SYM
cord-300883-rws11uel	110	26	36.651	36.651	CD
cord-300883-rws11uel	110	27	)	)	-RRB-
cord-300883-rws11uel	110	28	years	year	NNS
cord-300883-rws11uel	110	29	,	,	,
cord-300883-rws11uel	110	30	respectively	respectively	RB
cord-300883-rws11uel	110	31	.	.	.
cord-300883-rws11uel	111	1	While	while	IN
cord-300883-rws11uel	111	2	the	the	DT
cord-300883-rws11uel	111	3	population	population	NN
cord-300883-rws11uel	111	4	size	size	NN
cord-300883-rws11uel	111	5	of	of	IN
cord-300883-rws11uel	111	6	lineage	lineage	NN
cord-300883-rws11uel	111	7	1	1	CD
cord-300883-rws11uel	111	8	recently	recently	RB
cord-300883-rws11uel	111	9	declined	decline	VBD
cord-300883-rws11uel	111	10	,	,	,
cord-300883-rws11uel	111	11	the	the	DT
cord-300883-rws11uel	111	12	lineage	lineage	NN
cord-300883-rws11uel	111	13	2	2	CD
cord-300883-rws11uel	111	14	population	population	NN
cord-300883-rws11uel	111	15	size	size	NN
cord-300883-rws11uel	111	16	did	do	VBD
cord-300883-rws11uel	111	17	not	not	RB
cord-300883-rws11uel	111	18	show	show	VB
cord-300883-rws11uel	111	19	any	any	DT
cord-300883-rws11uel	111	20	declining	decline	VBG
cord-300883-rws11uel	111	21	trend	trend	NN
cord-300883-rws11uel	111	22	.	.	.
cord-300883-rws11uel	112	1	This	this	DT
cord-300883-rws11uel	112	2	contrast	contrast	NN
cord-300883-rws11uel	112	3	in	in	IN
cord-300883-rws11uel	112	4	the	the	DT
cord-300883-rws11uel	112	5	population	population	NN
cord-300883-rws11uel	112	6	size	size	NN
cord-300883-rws11uel	112	7	could	could	MD
cord-300883-rws11uel	112	8	be	be	VB
cord-300883-rws11uel	112	9	associated	associate	VBN
cord-300883-rws11uel	112	10	with	with	IN
cord-300883-rws11uel	112	11	fitness	fitness	NN
cord-300883-rws11uel	112	12	of	of	IN
cord-300883-rws11uel	112	13	the	the	DT
cord-300883-rws11uel	112	14	virus	virus	NN
cord-300883-rws11uel	112	15	.	.	.
cord-300883-rws11uel	113	1	Despite	despite	IN
cord-300883-rws11uel	113	2	the	the	DT
cord-300883-rws11uel	113	3	weak	weak	JJ
cord-300883-rws11uel	113	4	temporal	temporal	JJ
cord-300883-rws11uel	113	5	and	and	CC
cord-300883-rws11uel	113	6	spatial	spatial	JJ
cord-300883-rws11uel	113	7	structure	structure	NN
cord-300883-rws11uel	113	8	,	,	,
cord-300883-rws11uel	113	9	viral	viral	JJ
cord-300883-rws11uel	113	10	strains	strain	NNS
cord-300883-rws11uel	113	11	belonging	belong	VBG
cord-300883-rws11uel	113	12	to	to	IN
cord-300883-rws11uel	113	13	lineage	lineage	NN
cord-300883-rws11uel	113	14	1a	1a	CD
cord-300883-rws11uel	114	1	(	(	-LRB-
cord-300883-rws11uel	114	2	Australia	Australia	NNP
cord-300883-rws11uel	114	3	,	,	,
cord-300883-rws11uel	114	4	Canada	Canada	NNP
cord-300883-rws11uel	114	5	,	,	,
cord-300883-rws11uel	114	6	The	the	DT
cord-300883-rws11uel	114	7	Netherlands	Netherlands	NNP
cord-300883-rws11uel	114	8	,	,	,
cord-300883-rws11uel	114	9	South	South	NNP
cord-300883-rws11uel	114	10	Africa	Africa	NNP
cord-300883-rws11uel	114	11	,	,	,
cord-300883-rws11uel	114	12	USA	USA	NNP
cord-300883-rws11uel	114	13	,	,	,
cord-300883-rws11uel	114	14	Argentina	Argentina	NNP
cord-300883-rws11uel	114	15	,	,	,
cord-300883-rws11uel	114	16	and	and	CC
cord-300883-rws11uel	114	17	Japan	Japan	NNP
cord-300883-rws11uel	114	18	)	)	-RRB-
cord-300883-rws11uel	114	19	and	and	CC
cord-300883-rws11uel	114	20	1b	1b	LS
cord-300883-rws11uel	114	21	(	(	-LRB-
cord-300883-rws11uel	114	22	Canada	Canada	NNP
cord-300883-rws11uel	114	23	,	,	,
cord-300883-rws11uel	114	24	The	the	DT
cord-300883-rws11uel	114	25	Netherlands	Netherlands	NNP
cord-300883-rws11uel	114	26	,	,	,
cord-300883-rws11uel	114	27	South	South	NNP
cord-300883-rws11uel	114	28	Africa	Africa	NNP
cord-300883-rws11uel	114	29	,	,	,
cord-300883-rws11uel	114	30	USA	USA	NNP
cord-300883-rws11uel	114	31	,	,	,
cord-300883-rws11uel	114	32	Japan	Japan	NNP
cord-300883-rws11uel	114	33	,	,	,
cord-300883-rws11uel	114	34	China	China	NNP
cord-300883-rws11uel	114	35	,	,	,
cord-300883-rws11uel	114	36	and	and	CC
cord-300883-rws11uel	114	37	Argentina	Argentina	NNP
cord-300883-rws11uel	114	38	)	)	-RRB-
cord-300883-rws11uel	114	39	have	have	VBP
cord-300883-rws11uel	114	40	a	a	DT
cord-300883-rws11uel	114	41	wider	wide	JJR
cord-300883-rws11uel	114	42	geographic	geographic	JJ
cord-300883-rws11uel	114	43	spread	spread	NN
cord-300883-rws11uel	114	44	than	than	IN
cord-300883-rws11uel	114	45	the	the	DT
cord-300883-rws11uel	114	46	strains	strain	NNS
cord-300883-rws11uel	114	47	belonging	belong	VBG
cord-300883-rws11uel	114	48	to	to	IN
cord-300883-rws11uel	114	49	lineage	lineage	NN
cord-300883-rws11uel	114	50	2a	2a	CD
cord-300883-rws11uel	114	51	(	(	-LRB-
cord-300883-rws11uel	114	52	Canada	Canada	NNP
cord-300883-rws11uel	114	53	,	,	,
cord-300883-rws11uel	114	54	UK	UK	NNP
cord-300883-rws11uel	114	55	,	,	,
cord-300883-rws11uel	114	56	The	the	DT
cord-300883-rws11uel	114	57	Netherlands	Netherlands	NNP
cord-300883-rws11uel	114	58	,	,	,
cord-300883-rws11uel	114	59	USA	USA	NNP
cord-300883-rws11uel	114	60	,	,	,
cord-300883-rws11uel	114	61	China	China	NNP
cord-300883-rws11uel	114	62	,	,	,
cord-300883-rws11uel	114	63	and	and	CC
cord-300883-rws11uel	114	64	South	South	NNP
cord-300883-rws11uel	114	65	Africa	Africa	NNP
cord-300883-rws11uel	114	66	)	)	-RRB-
cord-300883-rws11uel	114	67	and	and	CC
cord-300883-rws11uel	114	68	2b	2b	CD
cord-300883-rws11uel	115	1	(	(	-LRB-
cord-300883-rws11uel	115	2	The	the	DT
cord-300883-rws11uel	115	3	Netherlands	Netherlands	NNP
cord-300883-rws11uel	115	4	,	,	,
cord-300883-rws11uel	115	5	Canada	Canada	NNP
cord-300883-rws11uel	115	6	,	,	,
cord-300883-rws11uel	115	7	USA	USA	NNP
cord-300883-rws11uel	115	8	,	,	,
cord-300883-rws11uel	115	9	Peru	Peru	NNP
cord-300883-rws11uel	115	10	,	,	,
cord-300883-rws11uel	115	11	and	and	CC
cord-300883-rws11uel	115	12	Japan	Japan	NNP
cord-300883-rws11uel	115	13	)	)	-RRB-
cord-300883-rws11uel	115	14	,	,	,
cord-300883-rws11uel	115	15	indicating	indicate	VBG
cord-300883-rws11uel	115	16	that	that	IN
cord-300883-rws11uel	115	17	fitness	fitness	NN
cord-300883-rws11uel	115	18	of	of	IN
cord-300883-rws11uel	115	19	the	the	DT
cord-300883-rws11uel	115	20	viral	viral	JJ
cord-300883-rws11uel	115	21	strains	strain	NNS
cord-300883-rws11uel	115	22	might	may	MD
cord-300883-rws11uel	115	23	have	have	VB
cord-300883-rws11uel	115	24	Estimates	estimate	NNS
cord-300883-rws11uel	115	25	with	with	IN
cord-300883-rws11uel	115	26	relaxed	relaxed	JJ
cord-300883-rws11uel	115	27	clock	clock	NN
cord-300883-rws11uel	115	28	are	be	VBP
cord-300883-rws11uel	115	29	better	well	RBR
cord-300883-rws11uel	115	30	fit	fit	JJ
cord-300883-rws11uel	115	31	to	to	IN
cord-300883-rws11uel	115	32	the	the	DT
cord-300883-rws11uel	115	33	data	datum	NNS
cord-300883-rws11uel	115	34	.	.	.
cord-300883-rws11uel	116	1	played	play	VBD
cord-300883-rws11uel	116	2	a	a	DT
cord-300883-rws11uel	116	3	crucial	crucial	JJ
cord-300883-rws11uel	116	4	role	role	NN
cord-300883-rws11uel	116	5	in	in	IN
cord-300883-rws11uel	116	6	the	the	DT
cord-300883-rws11uel	116	7	uneven	uneven	JJ
cord-300883-rws11uel	116	8	distribution	distribution	NN
cord-300883-rws11uel	116	9	across	across	IN
cord-300883-rws11uel	116	10	the	the	DT
cord-300883-rws11uel	116	11	wide	wide	JJ
cord-300883-rws11uel	116	12	geographic	geographic	JJ
cord-300883-rws11uel	116	13	regions	region	NNS
cord-300883-rws11uel	116	14	.	.	.
cord-300883-rws11uel	117	1	The	the	DT
cord-300883-rws11uel	117	2	extensive	extensive	JJ
cord-300883-rws11uel	117	3	polymorphisms	polymorphism	NNS
cord-300883-rws11uel	117	4	of	of	IN
cord-300883-rws11uel	117	5	the	the	DT
cord-300883-rws11uel	117	6	hMPV	hmpv	NN
cord-300883-rws11uel	117	7	G	g	NN
cord-300883-rws11uel	117	8	-	-	HYPH
cord-300883-rws11uel	117	9	gene	gene	NN
cord-300883-rws11uel	117	10	may	may	MD
cord-300883-rws11uel	117	11	have	have	VB
cord-300883-rws11uel	117	12	resulted	result	VBN
cord-300883-rws11uel	117	13	from	from	IN
cord-300883-rws11uel	117	14	mutations	mutation	NNS
cord-300883-rws11uel	117	15	occurring	occur	VBG
cord-300883-rws11uel	117	16	during	during	IN
cord-300883-rws11uel	117	17	virus	virus	NN
cord-300883-rws11uel	117	18	propagation	propagation	NN
cord-300883-rws11uel	117	19	in	in	IN
cord-300883-rws11uel	117	20	cell	cell	NN
cord-300883-rws11uel	117	21	culture	culture	NN
cord-300883-rws11uel	117	22	;	;	:
cord-300883-rws11uel	117	23	however	however	RB
cord-300883-rws11uel	117	24	,	,	,
cord-300883-rws11uel	117	25	Peret	Peret	NNP
cord-300883-rws11uel	117	26	et	et	NNP
cord-300883-rws11uel	117	27	al	al	NNP
cord-300883-rws11uel	117	28	.	.	.
cord-300883-rws11uel	118	1	(	(	-LRB-
cord-300883-rws11uel	118	2	2004	2004	CD
cord-300883-rws11uel	118	3	)	)	-RRB-
cord-300883-rws11uel	118	4	reported	report	VBD
cord-300883-rws11uel	118	5	identical	identical	JJ
cord-300883-rws11uel	118	6	sequences	sequence	NNS
cord-300883-rws11uel	118	7	of	of	IN
cord-300883-rws11uel	118	8	the	the	DT
cord-300883-rws11uel	118	9	same	same	JJ
cord-300883-rws11uel	118	10	viral	viral	JJ
cord-300883-rws11uel	118	11	strain	strain	NN
cord-300883-rws11uel	118	12	after	after	IN
cord-300883-rws11uel	118	13	multiple	multiple	JJ
cord-300883-rws11uel	118	14	passages	passage	NNS
cord-300883-rws11uel	118	15	,	,	,
cord-300883-rws11uel	118	16	and	and	CC
cord-300883-rws11uel	118	17	thus	thus	RB
cord-300883-rws11uel	118	18	,	,	,
cord-300883-rws11uel	118	19	the	the	DT
cord-300883-rws11uel	118	20	observed	observed	JJ
cord-300883-rws11uel	118	21	variation	variation	NN
cord-300883-rws11uel	118	22	in	in	IN
cord-300883-rws11uel	118	23	the	the	DT
cord-300883-rws11uel	118	24	G	g	NN
cord-300883-rws11uel	118	25	-	-	HYPH
cord-300883-rws11uel	118	26	gene	gene	NN
cord-300883-rws11uel	118	27	of	of	IN
cord-300883-rws11uel	118	28	hMPVs	hmpvs	CD
cord-300883-rws11uel	118	29	due	due	IN
cord-300883-rws11uel	118	30	to	to	IN
cord-300883-rws11uel	118	31	multiple	multiple	JJ
cord-300883-rws11uel	118	32	passages	passage	NNS
cord-300883-rws11uel	118	33	is	be	VBZ
cord-300883-rws11uel	118	34	more	more	RBR
cord-300883-rws11uel	118	35	unlikely	unlikely	JJ
cord-300883-rws11uel	118	36	.	.	.
cord-300883-rws11uel	119	1	However	however	RB
cord-300883-rws11uel	119	2	,	,	,
cord-300883-rws11uel	119	3	it	-PRON-	PRP
cord-300883-rws11uel	119	4	is	be	VBZ
cord-300883-rws11uel	119	5	unclear	unclear	JJ
cord-300883-rws11uel	119	6	whether	whether	IN
cord-300883-rws11uel	119	7	the	the	DT
cord-300883-rws11uel	119	8	hMPV	hmpv	NN
cord-300883-rws11uel	119	9	G	g	NN
cord-300883-rws11uel	119	10	-	-	HYPH
cord-300883-rws11uel	119	11	gene	gene	NN
cord-300883-rws11uel	119	12	experienced	experience	VBD
cord-300883-rws11uel	119	13	differential	differential	JJ
cord-300883-rws11uel	119	14	selection	selection	NN
cord-300883-rws11uel	119	15	pressures	pressure	NNS
cord-300883-rws11uel	119	16	,	,	,
cord-300883-rws11uel	119	17	or	or	CC
cord-300883-rws11uel	119	18	all	all	PDT
cord-300883-rws11uel	119	19	the	the	DT
cord-300883-rws11uel	119	20	deduced	deduce	VBN
cord-300883-rws11uel	119	21	amino	amino	NN
cord-300883-rws11uel	119	22	acid	acid	NN
cord-300883-rws11uel	119	23	sites	site	NNS
cord-300883-rws11uel	119	24	evolved	evolve	VBD
cord-300883-rws11uel	119	25	due	due	JJ
cord-300883-rws11uel	119	26	to	to	IN
cord-300883-rws11uel	119	27	stochastic	stochastic	JJ
cord-300883-rws11uel	119	28	mutational	mutational	JJ
cord-300883-rws11uel	119	29	processes	process	NNS
cord-300883-rws11uel	119	30	?	?	.
cord-300883-rws11uel	120	1	Sliding	slide	VBG
cord-300883-rws11uel	120	2	window	window	NN
cord-300883-rws11uel	120	3	analyses	analysis	NNS
cord-300883-rws11uel	120	4	of	of	IN
cord-300883-rws11uel	120	5	each	each	DT
cord-300883-rws11uel	120	6	lineage	lineage	NN
cord-300883-rws11uel	120	7	revealed	reveal	VBD
cord-300883-rws11uel	120	8	that	that	IN
cord-300883-rws11uel	120	9	in	in	IN
cord-300883-rws11uel	120	10	the	the	DT
cord-300883-rws11uel	120	11	majority	majority	NN
cord-300883-rws11uel	120	12	of	of	IN
cord-300883-rws11uel	120	13	regions	region	NNS
cord-300883-rws11uel	120	14	synonymous	synonymous	JJ
cord-300883-rws11uel	120	15	divergence	divergence	NN
cord-300883-rws11uel	120	16	exceeds	exceed	VBZ
cord-300883-rws11uel	120	17	the	the	DT
cord-300883-rws11uel	120	18	corresponding	correspond	VBG
cord-300883-rws11uel	120	19	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	120	20	divergence	divergence	NN
cord-300883-rws11uel	120	21	,	,	,
cord-300883-rws11uel	120	22	thus	thus	RB
cord-300883-rws11uel	120	23	suggesting	suggest	VBG
cord-300883-rws11uel	120	24	that	that	IN
cord-300883-rws11uel	120	25	the	the	DT
cord-300883-rws11uel	120	26	G	g	NN
cord-300883-rws11uel	120	27	-	-	HYPH
cord-300883-rws11uel	120	28	gene	gene	NN
cord-300883-rws11uel	120	29	of	of	IN
cord-300883-rws11uel	120	30	hMPV	hmpv	NN
cord-300883-rws11uel	120	31	is	be	VBZ
cord-300883-rws11uel	120	32	influenced	influence	VBN
cord-300883-rws11uel	120	33	by	by	IN
cord-300883-rws11uel	120	34	purifying	purify	VBG
cord-300883-rws11uel	120	35	selection	selection	NN
cord-300883-rws11uel	121	1	(	(	-LRB-
cord-300883-rws11uel	121	2	Fig	Fig	NNP
cord-300883-rws11uel	121	3	.	.	NNP
cord-300883-rws11uel	121	4	1	1	CD
cord-300883-rws11uel	121	5	)	)	-RRB-
cord-300883-rws11uel	121	6	.	.	.
cord-300883-rws11uel	122	1	However	however	RB
cord-300883-rws11uel	122	2	,	,	,
cord-300883-rws11uel	122	3	a	a	DT
cord-300883-rws11uel	122	4	few	few	JJ
cord-300883-rws11uel	122	5	coding	code	VBG
cord-300883-rws11uel	122	6	regions	region	NNS
cord-300883-rws11uel	122	7	in	in	IN
cord-300883-rws11uel	122	8	all	all	PDT
cord-300883-rws11uel	122	9	the	the	DT
cord-300883-rws11uel	122	10	lineages	lineage	NNS
cord-300883-rws11uel	122	11	showed	show	VBD
cord-300883-rws11uel	122	12	relatively	relatively	RB
cord-300883-rws11uel	122	13	higher	high	JJR
cord-300883-rws11uel	122	14	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	122	15	divergence	divergence	NN
cord-300883-rws11uel	122	16	than	than	IN
cord-300883-rws11uel	122	17	synonymous	synonymous	JJ
cord-300883-rws11uel	122	18	divergence	divergence	NN
cord-300883-rws11uel	122	19	,	,	,
cord-300883-rws11uel	122	20	therefore	therefore	RB
cord-300883-rws11uel	122	21	indicating	indicate	VBG
cord-300883-rws11uel	122	22	the	the	DT
cord-300883-rws11uel	122	23	pervasive	pervasive	JJ
cord-300883-rws11uel	122	24	role	role	NN
cord-300883-rws11uel	122	25	of	of	IN
cord-300883-rws11uel	122	26	positive	positive	JJ
cord-300883-rws11uel	122	27	selection	selection	NN
cord-300883-rws11uel	122	28	in	in	IN
cord-300883-rws11uel	122	29	certain	certain	JJ
cord-300883-rws11uel	122	30	amino	amino	NN
cord-300883-rws11uel	122	31	acid	acid	NN
cord-300883-rws11uel	122	32	sites	site	NNS
cord-300883-rws11uel	122	33	.	.	.
cord-300883-rws11uel	123	1	To	to	TO
cord-300883-rws11uel	123	2	identify	identify	VB
cord-300883-rws11uel	123	3	the	the	DT
cord-300883-rws11uel	123	4	codon	codon	NN
cord-300883-rws11uel	123	5	sites	site	NNS
cord-300883-rws11uel	123	6	that	that	WDT
cord-300883-rws11uel	123	7	are	be	VBP
cord-300883-rws11uel	123	8	positively	positively	RB
cord-300883-rws11uel	123	9	selected	select	VBN
cord-300883-rws11uel	123	10	,	,	,
cord-300883-rws11uel	123	11	we	-PRON-	PRP
cord-300883-rws11uel	123	12	performed	perform	VBD
cord-300883-rws11uel	123	13	ML	ml	NN
cord-300883-rws11uel	123	14	-	-	HYPH
cord-300883-rws11uel	123	15	based	base	VBN
cord-300883-rws11uel	123	16	codon	codon	NN
cord-300883-rws11uel	123	17	substitution	substitution	NN
cord-300883-rws11uel	123	18	analyses	analysis	NNS
cord-300883-rws11uel	123	19	.	.	.
cord-300883-rws11uel	124	1	Consistent	consistent	JJ
cord-300883-rws11uel	124	2	with	with	IN
cord-300883-rws11uel	124	3	sliding	slide	VBG
cord-300883-rws11uel	124	4	window	window	NN
cord-300883-rws11uel	124	5	results	result	NNS
cord-300883-rws11uel	124	6	,	,	,
cord-300883-rws11uel	124	7	the	the	DT
cord-300883-rws11uel	124	8	M0	m0	NN
cord-300883-rws11uel	124	9	model	model	NN
cord-300883-rws11uel	124	10	revealed	reveal	VBD
cord-300883-rws11uel	124	11	that	that	IN
cord-300883-rws11uel	124	12	the	the	DT
cord-300883-rws11uel	124	13	average	average	JJ
cord-300883-rws11uel	124	14	ω	ω	NN
cord-300883-rws11uel	124	15	for	for	IN
cord-300883-rws11uel	124	16	each	each	DT
cord-300883-rws11uel	124	17	lineage	lineage	NN
cord-300883-rws11uel	124	18	is	be	VBZ
cord-300883-rws11uel	124	19	less	less	JJR
cord-300883-rws11uel	124	20	than	than	IN
cord-300883-rws11uel	124	21	one	one	CD
cord-300883-rws11uel	124	22	(	(	-LRB-
cord-300883-rws11uel	124	23	Table	Table	NNP
cord-300883-rws11uel	124	24	3	3	CD
cord-300883-rws11uel	124	25	)	)	-RRB-
cord-300883-rws11uel	124	26	,	,	,
cord-300883-rws11uel	124	27	thus	thus	RB
cord-300883-rws11uel	124	28	suggesting	suggest	VBG
cord-300883-rws11uel	124	29	each	each	DT
cord-300883-rws11uel	124	30	lineage	lineage	NN
cord-300883-rws11uel	124	31	experienced	experience	VBD
cord-300883-rws11uel	124	32	purifying	purify	VBG
cord-300883-rws11uel	124	33	selection	selection	NN
cord-300883-rws11uel	124	34	.	.	.
cord-300883-rws11uel	125	1	However	however	RB
cord-300883-rws11uel	125	2	,	,	,
cord-300883-rws11uel	125	3	comparison	comparison	NN
cord-300883-rws11uel	125	4	of	of	IN
cord-300883-rws11uel	125	5	the	the	DT
cord-300883-rws11uel	125	6	models	model	NNS
cord-300883-rws11uel	125	7	that	that	WDT
cord-300883-rws11uel	125	8	assume	assume	VBP
cord-300883-rws11uel	125	9	positive	positive	JJ
cord-300883-rws11uel	125	10	selection	selection	NN
cord-300883-rws11uel	125	11	(	(	-LRB-
cord-300883-rws11uel	125	12	M2a	M2a	NNP
cord-300883-rws11uel	125	13	,	,	,
cord-300883-rws11uel	125	14	M8	m8	NN
cord-300883-rws11uel	125	15	)	)	-RRB-
cord-300883-rws11uel	125	16	with	with	IN
cord-300883-rws11uel	125	17	the	the	DT
cord-300883-rws11uel	125	18	models	model	NNS
cord-300883-rws11uel	125	19	(	(	-LRB-
cord-300883-rws11uel	125	20	M1a	M1a	NNP
cord-300883-rws11uel	125	21	,	,	,
cord-300883-rws11uel	125	22	M7	m7	NN
cord-300883-rws11uel	125	23	,	,	,
cord-300883-rws11uel	125	24	and	and	CC
cord-300883-rws11uel	125	25	M8a	M8a	NNP
cord-300883-rws11uel	125	26	)	)	-RRB-
cord-300883-rws11uel	125	27	that	that	WDT
cord-300883-rws11uel	125	28	assume	assume	VBP
cord-300883-rws11uel	125	29	no	no	DT
cord-300883-rws11uel	125	30	positive	positive	JJ
cord-300883-rws11uel	125	31	selection	selection	NN
cord-300883-rws11uel	125	32	,	,	,
cord-300883-rws11uel	125	33	detected	detect	VBD
cord-300883-rws11uel	125	34	approximately	approximately	RB
cord-300883-rws11uel	125	35	6	6	CD
cord-300883-rws11uel	125	36	%	%	NN
cord-300883-rws11uel	125	37	,	,	,
cord-300883-rws11uel	125	38	1.3	1.3	CD
cord-300883-rws11uel	125	39	%	%	NN
cord-300883-rws11uel	125	40	,	,	,
cord-300883-rws11uel	125	41	7.3	7.3	CD
cord-300883-rws11uel	125	42	%	%	NN
cord-300883-rws11uel	125	43	,	,	,
cord-300883-rws11uel	125	44	and	and	CC
cord-300883-rws11uel	125	45	3	3	CD
cord-300883-rws11uel	125	46	%	%	NN
cord-300883-rws11uel	125	47	positively	positively	RB
cord-300883-rws11uel	125	48	selected	select	VBN
cord-300883-rws11uel	125	49	codons	codon	NNS
cord-300883-rws11uel	125	50	in	in	IN
cord-300883-rws11uel	125	51	lineage	lineage	NN
cord-300883-rws11uel	125	52	1a	1a	CD
cord-300883-rws11uel	125	53	,	,	,
cord-300883-rws11uel	125	54	1b	1b	CD
cord-300883-rws11uel	125	55	,	,	,
cord-300883-rws11uel	125	56	2a	2a	CD
cord-300883-rws11uel	125	57	,	,	,
cord-300883-rws11uel	125	58	and	and	CC
cord-300883-rws11uel	125	59	2b	2b	NNP
cord-300883-rws11uel	125	60	,	,	,
cord-300883-rws11uel	125	61	respectively	respectively	RB
cord-300883-rws11uel	125	62	(	(	-LRB-
cord-300883-rws11uel	125	63	Table	table	NN
cord-300883-rws11uel	125	64	3	3	CD
cord-300883-rws11uel	125	65	)	)	-RRB-
cord-300883-rws11uel	125	66	.	.	.
cord-300883-rws11uel	126	1	There	there	EX
cord-300883-rws11uel	126	2	are	be	VBP
cord-300883-rws11uel	126	3	eight	eight	CD
cord-300883-rws11uel	126	4	positively	positively	RB
cord-300883-rws11uel	126	5	selected	select	VBN
cord-300883-rws11uel	126	6	sites	site	NNS
cord-300883-rws11uel	126	7	(	(	-LRB-
cord-300883-rws11uel	126	8	site	site	NN
cord-300883-rws11uel	126	9	93	93	CD
cord-300883-rws11uel	126	10	,	,	,
cord-300883-rws11uel	126	11	105	105	CD
cord-300883-rws11uel	126	12	,	,	,
cord-300883-rws11uel	126	13	106	106	CD
cord-300883-rws11uel	126	14	,	,	,
cord-300883-rws11uel	126	15	154	154	CD
cord-300883-rws11uel	126	16	,	,	,
cord-300883-rws11uel	126	17	158	158	CD
cord-300883-rws11uel	126	18	,	,	,
cord-300883-rws11uel	126	19	171	171	CD
cord-300883-rws11uel	126	20	,	,	,
cord-300883-rws11uel	126	21	173	173	CD
cord-300883-rws11uel	126	22	,	,	,
cord-300883-rws11uel	126	23	and	and	CC
cord-300883-rws11uel	126	24	188	188	CD
cord-300883-rws11uel	126	25	)	)	-RRB-
cord-300883-rws11uel	126	26	with	with	IN
cord-300883-rws11uel	126	27	posterior	posterior	JJ
cord-300883-rws11uel	126	28	probability	probability	NN
cord-300883-rws11uel	126	29	≥0.95	≥0.95	CD
cord-300883-rws11uel	126	30	within	within	IN
cord-300883-rws11uel	126	31	lineage	lineage	NN
cord-300883-rws11uel	126	32	1a	1a	NN
cord-300883-rws11uel	126	33	,	,	,
cord-300883-rws11uel	126	34	whereas	whereas	IN
cord-300883-rws11uel	126	35	lineage	lineage	NN
cord-300883-rws11uel	126	36	1b	1b	CD
cord-300883-rws11uel	126	37	(	(	-LRB-
cord-300883-rws11uel	126	38	site	site	NN
cord-300883-rws11uel	126	39	146	146	CD
cord-300883-rws11uel	126	40	,	,	,
cord-300883-rws11uel	126	41	183	183	CD
cord-300883-rws11uel	126	42	,	,	,
cord-300883-rws11uel	126	43	and	and	CC
cord-300883-rws11uel	126	44	196	196	CD
cord-300883-rws11uel	126	45	)	)	-RRB-
cord-300883-rws11uel	126	46	and	and	CC
cord-300883-rws11uel	126	47	lineage	lineage	NN
cord-300883-rws11uel	126	48	2a	2a	CD
cord-300883-rws11uel	126	49	(	(	-LRB-
cord-300883-rws11uel	126	50	85	85	CD
cord-300883-rws11uel	126	51	,	,	,
cord-300883-rws11uel	126	52	232	232	CD
cord-300883-rws11uel	126	53	,	,	,
cord-300883-rws11uel	126	54	and	and	CC
cord-300883-rws11uel	126	55	239	239	CD
cord-300883-rws11uel	126	56	)	)	-RRB-
cord-300883-rws11uel	126	57	each	each	DT
cord-300883-rws11uel	126	58	have	have	VBP
cord-300883-rws11uel	126	59	three	three	CD
cord-300883-rws11uel	126	60	positively	positively	RB
cord-300883-rws11uel	126	61	selected	select	VBN
cord-300883-rws11uel	126	62	sites	site	NNS
cord-300883-rws11uel	126	63	with	with	IN
cord-300883-rws11uel	126	64	posterior	posterior	JJ
cord-300883-rws11uel	126	65	probability	probability	NN
cord-300883-rws11uel	126	66	≥0.95	≥0.95	CD
cord-300883-rws11uel	126	67	.	.	.
cord-300883-rws11uel	127	1	Lineage	lineage	NN
cord-300883-rws11uel	127	2	2b	2b	NNP
cord-300883-rws11uel	127	3	has	have	VBZ
cord-300883-rws11uel	127	4	only	only	RB
cord-300883-rws11uel	127	5	two	two	CD
cord-300883-rws11uel	127	6	positively	positively	RB
cord-300883-rws11uel	127	7	selected	select	VBN
cord-300883-rws11uel	127	8	sites	site	NNS
cord-300883-rws11uel	127	9	(	(	-LRB-
cord-300883-rws11uel	127	10	site	site	NN
cord-300883-rws11uel	127	11	100	100	CD
cord-300883-rws11uel	127	12	and	and	CC
cord-300883-rws11uel	127	13	105	105	CD
cord-300883-rws11uel	127	14	)	)	-RRB-
cord-300883-rws11uel	127	15	with	with	IN
cord-300883-rws11uel	127	16	posterior	posterior	JJ
cord-300883-rws11uel	127	17	probability	probability	NN
cord-300883-rws11uel	127	18	≥0.95	≥0.95	CD
cord-300883-rws11uel	127	19	.	.	.
cord-300883-rws11uel	128	1	Except	except	IN
cord-300883-rws11uel	128	2	site	site	NN
cord-300883-rws11uel	128	3	105	105	CD
cord-300883-rws11uel	128	4	,	,	,
cord-300883-rws11uel	128	5	which	which	WDT
cord-300883-rws11uel	128	6	is	be	VBZ
cord-300883-rws11uel	128	7	positively	positively	RB
cord-300883-rws11uel	128	8	selected	select	VBN
cord-300883-rws11uel	128	9	in	in	IN
cord-300883-rws11uel	128	10	lineage	lineage	NN
cord-300883-rws11uel	128	11	1a	1a	NN
cord-300883-rws11uel	128	12	and	and	CC
cord-300883-rws11uel	128	13	2b	2b	NNP
cord-300883-rws11uel	128	14	,	,	,
cord-300883-rws11uel	128	15	none	none	NN
cord-300883-rws11uel	128	16	of	of	IN
cord-300883-rws11uel	128	17	the	the	DT
cord-300883-rws11uel	128	18	positively	positively	RB
cord-300883-rws11uel	128	19	selected	select	VBN
cord-300883-rws11uel	128	20	sites	site	NNS
cord-300883-rws11uel	128	21	are	be	VBP
cord-300883-rws11uel	128	22	overlapping	overlap	VBG
cord-300883-rws11uel	128	23	among	among	IN
cord-300883-rws11uel	128	24	the	the	DT
cord-300883-rws11uel	128	25	lineages	lineage	NNS
cord-300883-rws11uel	128	26	.	.	.
cord-300883-rws11uel	129	1	It	-PRON-	PRP
cord-300883-rws11uel	129	2	is	be	VBZ
cord-300883-rws11uel	129	3	unclear	unclear	JJ
cord-300883-rws11uel	129	4	whether	whether	IN
cord-300883-rws11uel	129	5	these	these	DT
cord-300883-rws11uel	129	6	positively	positively	RB
cord-300883-rws11uel	129	7	selected	select	VBN
cord-300883-rws11uel	129	8	sites	site	NNS
cord-300883-rws11uel	129	9	are	be	VBP
cord-300883-rws11uel	129	10	associated	associate	VBN
cord-300883-rws11uel	129	11	with	with	IN
cord-300883-rws11uel	129	12	the	the	DT
cord-300883-rws11uel	129	13	fitness	fitness	NN
cord-300883-rws11uel	129	14	of	of	IN
cord-300883-rws11uel	129	15	this	this	DT
cord-300883-rws11uel	129	16	virus	virus	NN
cord-300883-rws11uel	129	17	.	.	.
cord-300883-rws11uel	130	1	Research	research	NN
cord-300883-rws11uel	130	2	with	with	IN
cord-300883-rws11uel	130	3	monoclonal	monoclonal	JJ
cord-300883-rws11uel	130	4	antibodies	antibody	NNS
cord-300883-rws11uel	130	5	has	have	VBZ
cord-300883-rws11uel	130	6	shown	show	VBN
cord-300883-rws11uel	130	7	that	that	IN
cord-300883-rws11uel	130	8	the	the	DT
cord-300883-rws11uel	130	9	hMPV	hmpv	NN
cord-300883-rws11uel	130	10	F	F	NNP
cord-300883-rws11uel	130	11	-	-	HYPH
cord-300883-rws11uel	130	12	protein	protein	NNP
cord-300883-rws11uel	130	13	carries	carry	VBZ
cord-300883-rws11uel	130	14	neutralizing	neutralize	VBG
cord-300883-rws11uel	130	15	epitopes	epitope	NNS
cord-300883-rws11uel	130	16	(	(	-LRB-
cord-300883-rws11uel	130	17	Skiadopoulos	Skiadopoulos	NNP
cord-300883-rws11uel	130	18	et	et	NNP
cord-300883-rws11uel	130	19	al	al	NNP
cord-300883-rws11uel	130	20	.	.	NNP
cord-300883-rws11uel	130	21	,	,	,
cord-300883-rws11uel	130	22	2004	2004	CD
cord-300883-rws11uel	130	23	;	;	:
cord-300883-rws11uel	130	24	Ulbrand	Ulbrand	NNP
cord-300883-rws11uel	130	25	et	et	NNP
cord-300883-rws11uel	130	26	al	al	NNP
cord-300883-rws11uel	130	27	.	.	NNP
cord-300883-rws11uel	130	28	,	,	,
cord-300883-rws11uel	130	29	2006	2006	CD
cord-300883-rws11uel	130	30	)	)	-RRB-
cord-300883-rws11uel	130	31	;	;	:
cord-300883-rws11uel	130	32	therefore	therefore	RB
cord-300883-rws11uel	130	33	,	,	,
cord-300883-rws11uel	130	34	antigenic	antigenic	JJ
cord-300883-rws11uel	130	35	variation	variation	NN
cord-300883-rws11uel	130	36	due	due	JJ
cord-300883-rws11uel	130	37	to	to	IN
cord-300883-rws11uel	130	38	immune	immune	JJ
cord-300883-rws11uel	130	39	selection	selection	NN
cord-300883-rws11uel	130	40	in	in	IN
cord-300883-rws11uel	130	41	the	the	DT
cord-300883-rws11uel	130	42	hMPV	hmpv	NN
cord-300883-rws11uel	130	43	F	F	NNP
cord-300883-rws11uel	130	44	-	-	HYPH
cord-300883-rws11uel	130	45	protein	protein	NNP
cord-300883-rws11uel	130	46	is	be	VBZ
cord-300883-rws11uel	130	47	more	more	RBR
cord-300883-rws11uel	130	48	likely	likely	JJ
cord-300883-rws11uel	130	49	.	.	.
cord-300883-rws11uel	131	1	Although	although	IN
cord-300883-rws11uel	131	2	,	,	,
cord-300883-rws11uel	131	3	the	the	DT
cord-300883-rws11uel	131	4	overall	overall	JJ
cord-300883-rws11uel	131	5	excess	excess	NN
cord-300883-rws11uel	131	6	of	of	IN
cord-300883-rws11uel	131	7	synonymous	synonymous	JJ
cord-300883-rws11uel	131	8	substitutions	substitution	NNS
cord-300883-rws11uel	131	9	at	at	IN
cord-300883-rws11uel	131	10	the	the	DT
cord-300883-rws11uel	131	11	hMPV	hmpv	NN
cord-300883-rws11uel	131	12	G	g	NN
cord-300883-rws11uel	131	13	-	-	HYPH
cord-300883-rws11uel	131	14	protein	protein	NN
cord-300883-rws11uel	131	15	indicates	indicate	VBZ
cord-300883-rws11uel	131	16	that	that	IN
cord-300883-rws11uel	131	17	host	host	NN
cord-300883-rws11uel	131	18	immune	immune	NN
cord-300883-rws11uel	131	19	selection	selection	NN
cord-300883-rws11uel	131	20	might	may	MD
cord-300883-rws11uel	131	21	not	not	RB
cord-300883-rws11uel	131	22	be	be	VB
cord-300883-rws11uel	131	23	the	the	DT
cord-300883-rws11uel	131	24	dominant	dominant	JJ
cord-300883-rws11uel	131	25	selective	selective	JJ
cord-300883-rws11uel	131	26	force	force	NN
cord-300883-rws11uel	131	27	,	,	.
cord-300883-rws11uel	132	1	the	the	DT
cord-300883-rws11uel	132	2	findings	finding	NNS
cord-300883-rws11uel	132	3	of	of	IN
cord-300883-rws11uel	132	4	several	several	JJ
cord-300883-rws11uel	132	5	hotspots	hotspot	NNS
cord-300883-rws11uel	132	6	of	of	IN
cord-300883-rws11uel	132	7	nonsynonymous	nonsynonymous	JJ
cord-300883-rws11uel	132	8	substitutions	substitution	NNS
cord-300883-rws11uel	132	9	in	in	IN
cord-300883-rws11uel	132	10	this	this	DT
cord-300883-rws11uel	132	11	protein	protein	NN
cord-300883-rws11uel	132	12	suggests	suggest	VBZ
cord-300883-rws11uel	132	13	that	that	IN
cord-300883-rws11uel	132	14	host	host	NN
cord-300883-rws11uel	132	15	immune	immune	NN
cord-300883-rws11uel	132	16	selection	selection	NN
cord-300883-rws11uel	132	17	might	may	MD
cord-300883-rws11uel	132	18	also	also	RB
cord-300883-rws11uel	132	19	play	play	VB
cord-300883-rws11uel	132	20	a	a	DT
cord-300883-rws11uel	132	21	role	role	NN
cord-300883-rws11uel	132	22	in	in	IN
cord-300883-rws11uel	132	23	maintaining	maintain	VBG
cord-300883-rws11uel	132	24	diversity	diversity	NN
cord-300883-rws11uel	132	25	.	.	.
cord-300883-rws11uel	133	1	Recent	recent	JJ
cord-300883-rws11uel	133	2	study	study	NN
cord-300883-rws11uel	133	3	has	have	VBZ
cord-300883-rws11uel	133	4	shown	show	VBN
cord-300883-rws11uel	133	5	that	that	IN
cord-300883-rws11uel	133	6	a	a	DT
cord-300883-rws11uel	133	7	majority	majority	NN
cord-300883-rws11uel	133	8	of	of	IN
cord-300883-rws11uel	133	9	the	the	DT
cord-300883-rws11uel	133	10	neutralizing	neutralize	VBG
cord-300883-rws11uel	133	11	epitopes	epitope	NNS
cord-300883-rws11uel	133	12	in	in	IN
cord-300883-rws11uel	133	13	the	the	DT
cord-300883-rws11uel	133	14	HRSV	HRSV	NNP
cord-300883-rws11uel	133	15	G	g	NN
cord-300883-rws11uel	133	16	-	-	HYPH
cord-300883-rws11uel	133	17	gene	gene	NN
cord-300883-rws11uel	133	18	is	be	VBZ
cord-300883-rws11uel	133	19	strongly	strongly	RB
cord-300883-rws11uel	133	20	associated	associate	VBN
cord-300883-rws11uel	133	21	with	with	IN
cord-300883-rws11uel	133	22	positively	positively	RB
cord-300883-rws11uel	133	23	selected	select	VBN
cord-300883-rws11uel	133	24	sites	site	NNS
cord-300883-rws11uel	133	25	,	,	,
cord-300883-rws11uel	133	26	and	and	CC
cord-300883-rws11uel	133	27	some	some	DT
cord-300883-rws11uel	133	28	of	of	IN
cord-300883-rws11uel	133	29	the	the	DT
cord-300883-rws11uel	133	30	positively	positively	RB
cord-300883-rws11uel	133	31	selected	select	VBN
cord-300883-rws11uel	133	32	sites	site	NNS
cord-300883-rws11uel	133	33	correspond	correspond	VBP
cord-300883-rws11uel	133	34	to	to	IN
cord-300883-rws11uel	133	35	the	the	DT
cord-300883-rws11uel	133	36	sites	site	NNS
cord-300883-rws11uel	133	37	of	of	IN
cord-300883-rws11uel	133	38	O	o	NN
cord-300883-rws11uel	133	39	-	-	HYPH
cord-300883-rws11uel	133	40	glycosylation	glycosylation	NN
cord-300883-rws11uel	133	41	(	(	-LRB-
cord-300883-rws11uel	133	42	Zlateva	Zlateva	NNP
cord-300883-rws11uel	133	43	et	et	FW
cord-300883-rws11uel	133	44	al	al	NNP
cord-300883-rws11uel	133	45	.	.	NNP
cord-300883-rws11uel	133	46	,	,	,
cord-300883-rws11uel	133	47	2004	2004	CD
cord-300883-rws11uel	133	48	)	)	-RRB-
cord-300883-rws11uel	133	49	.	.	.
cord-300883-rws11uel	134	1	Like	like	IN
cord-300883-rws11uel	134	2	HRSV	HRSV	NNP
cord-300883-rws11uel	134	3	,	,	,
cord-300883-rws11uel	134	4	although	although	IN
cord-300883-rws11uel	134	5	all	all	PDT
cord-300883-rws11uel	134	6	the	the	DT
cord-300883-rws11uel	134	7	positively	positively	RB
cord-300883-rws11uel	134	8	selected	select	VBN
cord-300883-rws11uel	134	9	codons	codon	NNS
cord-300883-rws11uel	134	10	of	of	IN
cord-300883-rws11uel	134	11	hMPV	hmpv	NN
cord-300883-rws11uel	134	12	G	g	NN
cord-300883-rws11uel	134	13	-	-	HYPH
cord-300883-rws11uel	134	14	gene	gene	NN
cord-300883-rws11uel	134	15	are	be	VBP
cord-300883-rws11uel	134	16	located	locate	VBN
cord-300883-rws11uel	134	17	in	in	IN
cord-300883-rws11uel	134	18	the	the	DT
cord-300883-rws11uel	134	19	extracellular	extracellular	JJ
cord-300883-rws11uel	134	20	domain	domain	NN
cord-300883-rws11uel	134	21	and	and	CC
cord-300883-rws11uel	134	22	some	some	DT
cord-300883-rws11uel	134	23	of	of	IN
cord-300883-rws11uel	134	24	them	-PRON-	PRP
cord-300883-rws11uel	134	25	correspond	correspond	VBP
cord-300883-rws11uel	134	26	to	to	IN
cord-300883-rws11uel	134	27	sites	site	NNS
cord-300883-rws11uel	134	28	of	of	IN
cord-300883-rws11uel	134	29	O	o	NN
cord-300883-rws11uel	134	30	-	-	HYPH
cord-300883-rws11uel	134	31	glycosylation	glycosylation	NN
cord-300883-rws11uel	134	32	,	,	,
cord-300883-rws11uel	134	33	the	the	DT
cord-300883-rws11uel	134	34	putative	putative	JJ
cord-300883-rws11uel	134	35	role	role	NN
cord-300883-rws11uel	134	36	is	be	VBZ
cord-300883-rws11uel	134	37	still	still	RB
cord-300883-rws11uel	134	38	unclear	unclear	JJ
cord-300883-rws11uel	134	39	for	for	IN
cord-300883-rws11uel	134	40	these	these	DT
cord-300883-rws11uel	134	41	positively	positively	RB
cord-300883-rws11uel	134	42	selected	select	VBN
cord-300883-rws11uel	134	43	sites	site	NNS
cord-300883-rws11uel	134	44	,	,	,
cord-300883-rws11uel	134	45	as	as	IN
cord-300883-rws11uel	134	46	is	be	VBZ
cord-300883-rws11uel	134	47	whether	whether	IN
cord-300883-rws11uel	134	48	some	some	DT
cord-300883-rws11uel	134	49	of	of	IN
cord-300883-rws11uel	134	50	these	these	DT
cord-300883-rws11uel	134	51	positively	positively	RB
cord-300883-rws11uel	134	52	selected	select	VBN
cord-300883-rws11uel	134	53	sites	site	NNS
cord-300883-rws11uel	134	54	are	be	VBP
cord-300883-rws11uel	134	55	associated	associate	VBN
cord-300883-rws11uel	134	56	with	with	IN
cord-300883-rws11uel	134	57	the	the	DT
cord-300883-rws11uel	134	58	region	region	NN
cord-300883-rws11uel	134	59	of	of	IN
cord-300883-rws11uel	134	60	antigenic	antigenic	JJ
cord-300883-rws11uel	134	61	determinants	determinant	NNS
cord-300883-rws11uel	134	62	.	.	.
cord-300883-rws11uel	135	1	We	-PRON-	PRP
cord-300883-rws11uel	135	2	intended	intend	VBD
cord-300883-rws11uel	135	3	to	to	TO
cord-300883-rws11uel	135	4	map	map	VB
cord-300883-rws11uel	135	5	these	these	DT
cord-300883-rws11uel	135	6	positively	positively	RB
cord-300883-rws11uel	135	7	selected	select	VBN
cord-300883-rws11uel	135	8	sites	site	NNS
cord-300883-rws11uel	135	9	with	with	IN
cord-300883-rws11uel	135	10	the	the	DT
cord-300883-rws11uel	135	11	HRSV	HRSV	NNP
cord-300883-rws11uel	135	12	G	g	NN
cord-300883-rws11uel	135	13	-	-	HYPH
cord-300883-rws11uel	135	14	protein	protein	NN
cord-300883-rws11uel	135	15	to	to	TO
cord-300883-rws11uel	135	16	see	see	VB
cord-300883-rws11uel	135	17	whether	whether	IN
cord-300883-rws11uel	135	18	the	the	DT
cord-300883-rws11uel	135	19	same	same	JJ
cord-300883-rws11uel	135	20	sites	site	NNS
cord-300883-rws11uel	135	21	were	be	VBD
cord-300883-rws11uel	135	22	also	also	RB
cord-300883-rws11uel	135	23	positively	positively	RB
cord-300883-rws11uel	135	24	selected	select	VBN
cord-300883-rws11uel	135	25	in	in	IN
cord-300883-rws11uel	135	26	HRSV	HRSV	NNP
cord-300883-rws11uel	136	1	(	(	-LRB-
cord-300883-rws11uel	136	2	Zlateva	Zlateva	NNP
cord-300883-rws11uel	136	3	et	et	FW
cord-300883-rws11uel	136	4	al	al	NNP
cord-300883-rws11uel	136	5	.	.	NNP
cord-300883-rws11uel	136	6	,	,	,
cord-300883-rws11uel	136	7	2004	2004	CD
cord-300883-rws11uel	137	1	(	(	-LRB-
cord-300883-rws11uel	137	2	Zlateva	Zlateva	NNP
cord-300883-rws11uel	137	3	et	et	FW
cord-300883-rws11uel	137	4	al	al	NNP
cord-300883-rws11uel	137	5	.	.	.
cord-300883-rws11uel	138	1	,	,	,
cord-300883-rws11uel	138	2	,	,	,
cord-300883-rws11uel	138	3	2005	2005	CD
cord-300883-rws11uel	138	4	;	;	:
cord-300883-rws11uel	138	5	however	however	RB
cord-300883-rws11uel	138	6	,	,	,
cord-300883-rws11uel	138	7	the	the	DT
cord-300883-rws11uel	138	8	predicted	predict	VBN
cord-300883-rws11uel	138	9	G	g	NN
cord-300883-rws11uel	138	10	-	-	HYPH
cord-300883-rws11uel	138	11	gene	gene	NN
cord-300883-rws11uel	138	12	amino	amino	NN
cord-300883-rws11uel	138	13	acid	acid	NN
cord-300883-rws11uel	138	14	sequences	sequence	NNS
cord-300883-rws11uel	138	15	of	of	IN
cord-300883-rws11uel	138	16	the	the	DT
cord-300883-rws11uel	138	17	two	two	CD
cord-300883-rws11uel	138	18	viruses	virus	NNS
cord-300883-rws11uel	138	19	could	could	MD
cord-300883-rws11uel	138	20	not	not	RB
cord-300883-rws11uel	138	21	be	be	VB
cord-300883-rws11uel	138	22	aligned	align	VBN
cord-300883-rws11uel	139	1	(	(	-LRB-
cord-300883-rws11uel	139	2	van	van	NNP
cord-300883-rws11uel	139	3	den	den	NNP
cord-300883-rws11uel	139	4	Hoogen	Hoogen	NNP
cord-300883-rws11uel	139	5	et	et	NNP
cord-300883-rws11uel	139	6	al	al	NNP
cord-300883-rws11uel	139	7	.	.	NNP
cord-300883-rws11uel	139	8	,	,	,
cord-300883-rws11uel	139	9	2002	2002	CD
cord-300883-rws11uel	139	10	;	;	:
cord-300883-rws11uel	139	11	Kahn	Kahn	NNP
cord-300883-rws11uel	139	12	,	,	,
cord-300883-rws11uel	139	13	2006	2006	CD
cord-300883-rws11uel	139	14	)	)	-RRB-
cord-300883-rws11uel	139	15	.	.	.
cord-300883-rws11uel	140	1	Although	although	IN
cord-300883-rws11uel	140	2	a	a	DT
cord-300883-rws11uel	140	3	vast	vast	JJ
cord-300883-rws11uel	140	4	majority	majority	NN
cord-300883-rws11uel	140	5	of	of	IN
cord-300883-rws11uel	140	6	codon	codon	NN
cord-300883-rws11uel	140	7	sites	site	NNS
cord-300883-rws11uel	140	8	(	(	-LRB-
cord-300883-rws11uel	140	9	>	>	NFP
cord-300883-rws11uel	140	10	95	95	CD
cord-300883-rws11uel	140	11	%	%	NN
cord-300883-rws11uel	140	12	in	in	IN
cord-300883-rws11uel	140	13	most	most	JJS
cord-300883-rws11uel	140	14	cases	case	NNS
cord-300883-rws11uel	140	15	)	)	-RRB-
cord-300883-rws11uel	140	16	are	be	VBP
cord-300883-rws11uel	140	17	shown	show	VBN
cord-300883-rws11uel	140	18	to	to	TO
cord-300883-rws11uel	140	19	have	have	VB
cord-300883-rws11uel	140	20	been	be	VBN
cord-300883-rws11uel	140	21	under	under	IN
cord-300883-rws11uel	140	22	purifying	purify	VBG
cord-300883-rws11uel	140	23	selection	selection	NN
cord-300883-rws11uel	140	24	,	,	,
cord-300883-rws11uel	140	25	significantly	significantly	RB
cord-300883-rws11uel	140	26	higher	high	JJR
cord-300883-rws11uel	140	27	ω	ω	NN
cord-300883-rws11uel	140	28	values	value	NNS
cord-300883-rws11uel	140	29	(	(	-LRB-
cord-300883-rws11uel	140	30	>	>	NFP
cord-300883-rws11uel	140	31	1	1	CD
cord-300883-rws11uel	140	32	)	)	-RRB-
cord-300883-rws11uel	140	33	at	at	IN
cord-300883-rws11uel	140	34	certain	certain	JJ
cord-300883-rws11uel	140	35	codon	codon	NN
cord-300883-rws11uel	140	36	sites	site	NNS
cord-300883-rws11uel	140	37	(	(	-LRB-
cord-300883-rws11uel	140	38	Table	Table	NNP
cord-300883-rws11uel	140	39	3	3	CD
cord-300883-rws11uel	140	40	)	)	-RRB-
cord-300883-rws11uel	140	41	indicate	indicate	VBP
cord-300883-rws11uel	140	42	the	the	DT
cord-300883-rws11uel	140	43	hMPV	hmpv	NN
cord-300883-rws11uel	140	44	G	g	NN
cord-300883-rws11uel	140	45	-	-	HYPH
cord-300883-rws11uel	140	46	gene	gene	NN
cord-300883-rws11uel	140	47	is	be	VBZ
cord-300883-rws11uel	140	48	under	under	IN
cord-300883-rws11uel	140	49	positive	positive	JJ
cord-300883-rws11uel	140	50	selection	selection	NN
cord-300883-rws11uel	140	51	.	.	.
cord-300883-rws11uel	141	1	Identification	identification	NN
cord-300883-rws11uel	141	2	of	of	IN
cord-300883-rws11uel	141	3	these	these	DT
cord-300883-rws11uel	141	4	positively	positively	RB
cord-300883-rws11uel	141	5	selected	select	VBN
cord-300883-rws11uel	141	6	amino	amino	NN
cord-300883-rws11uel	141	7	acid	acid	NN
cord-300883-rws11uel	141	8	sites	site	NNS
cord-300883-rws11uel	141	9	would	would	MD
cord-300883-rws11uel	141	10	help	help	VB
cord-300883-rws11uel	141	11	in	in	IN
cord-300883-rws11uel	141	12	better	well	JJR
cord-300883-rws11uel	141	13	screening	screening	NN
cord-300883-rws11uel	141	14	using	use	VBG
cord-300883-rws11uel	141	15	epitope	epitope	NN
cord-300883-rws11uel	141	16	mapping	mapping	NN
cord-300883-rws11uel	141	17	technology	technology	NN
cord-300883-rws11uel	141	18	to	to	TO
cord-300883-rws11uel	141	19	identify	identify	VB
cord-300883-rws11uel	141	20	and	and	CC
cord-300883-rws11uel	141	21	localize	localize	VB
cord-300883-rws11uel	141	22	the	the	DT
cord-300883-rws11uel	141	23	sites	site	NNS
cord-300883-rws11uel	141	24	that	that	WDT
cord-300883-rws11uel	141	25	can	can	MD
cord-300883-rws11uel	141	26	be	be	VB
cord-300883-rws11uel	141	27	recognized	recognize	VBN
cord-300883-rws11uel	141	28	by	by	IN
cord-300883-rws11uel	141	29	the	the	DT
cord-300883-rws11uel	141	30	immune	immune	JJ
cord-300883-rws11uel	141	31	system	system	NN
cord-300883-rws11uel	141	32	.	.	.
cord-300883-rws11uel	142	1	Knowledge	knowledge	NN
cord-300883-rws11uel	142	2	of	of	IN
cord-300883-rws11uel	142	3	sites	site	NNS
cord-300883-rws11uel	142	4	that	that	WDT
cord-300883-rws11uel	142	5	have	have	VBP
cord-300883-rws11uel	142	6	adaptively	adaptively	RB
cord-300883-rws11uel	142	7	evolved	evolve	VBN
cord-300883-rws11uel	142	8	can	can	MD
cord-300883-rws11uel	142	9	greatly	greatly	RB
cord-300883-rws11uel	142	10	cut	cut	VB
cord-300883-rws11uel	142	11	the	the	DT
cord-300883-rws11uel	142	12	cost	cost	NN
cord-300883-rws11uel	142	13	of	of	IN
cord-300883-rws11uel	142	14	these	these	DT
cord-300883-rws11uel	142	15	screening	screening	NN
cord-300883-rws11uel	142	16	processes	process	NNS
cord-300883-rws11uel	142	17	and	and	CC
cord-300883-rws11uel	142	18	thereby	thereby	RB
cord-300883-rws11uel	142	19	help	help	VB
cord-300883-rws11uel	142	20	in	in	IN
cord-300883-rws11uel	142	21	developing	develop	VBG
cord-300883-rws11uel	142	22	better	well	JJR
cord-300883-rws11uel	142	23	immunization	immunization	NN
cord-300883-rws11uel	142	24	techniques	technique	NNS
cord-300883-rws11uel	142	25	(	(	-LRB-
cord-300883-rws11uel	142	26	Mes	Mes	NNP
cord-300883-rws11uel	142	27	and	and	CC
cord-300883-rws11uel	142	28	van	van	NNP
cord-300883-rws11uel	142	29	Putten	Putten	NNP
cord-300883-rws11uel	142	30	,	,	,
cord-300883-rws11uel	142	31	2007	2007	CD
cord-300883-rws11uel	142	32	)	)	-RRB-
cord-300883-rws11uel	142	33	.	.	.
cord-300883-rws11uel	143	1	Genetic	genetic	JJ
cord-300883-rws11uel	143	2	variability	variability	NN
cord-300883-rws11uel	143	3	of	of	IN
cord-300883-rws11uel	143	4	the	the	DT
cord-300883-rws11uel	143	5	G	g	NN
cord-300883-rws11uel	143	6	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	143	7	gene	gene	NN
cord-300883-rws11uel	143	8	of	of	IN
cord-300883-rws11uel	143	9	human	human	JJ
cord-300883-rws11uel	143	10	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	143	11	Human	Human	NNP
cord-300883-rws11uel	143	12	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	143	13	infection	infection	NN
cord-300883-rws11uel	143	14	in	in	IN
cord-300883-rws11uel	143	15	the	the	DT
cord-300883-rws11uel	143	16	Canadian	canadian	JJ
cord-300883-rws11uel	143	17	population	population	NN
cord-300883-rws11uel	143	18	Genetic	genetic	JJ
cord-300883-rws11uel	143	19	diversity	diversity	NN
cord-300883-rws11uel	143	20	between	between	IN
cord-300883-rws11uel	143	21	human	human	JJ
cord-300883-rws11uel	143	22	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	143	23	subgroups	subgroup	NNS
cord-300883-rws11uel	144	1	An	an	DT
cord-300883-rws11uel	144	2	outbreak	outbreak	NN
cord-300883-rws11uel	144	3	of	of	IN
cord-300883-rws11uel	144	4	severe	severe	JJ
cord-300883-rws11uel	144	5	respiratory	respiratory	JJ
cord-300883-rws11uel	144	6	tract	tract	NN
cord-300883-rws11uel	144	7	infection	infection	NN
cord-300883-rws11uel	144	8	due	due	IN
cord-300883-rws11uel	144	9	to	to	IN
cord-300883-rws11uel	144	10	human	human	JJ
cord-300883-rws11uel	144	11	metapneumovirus	metapneumovirus	NN
cord-300883-rws11uel	144	12	in	in	IN
cord-300883-rws11uel	144	13	a	a	DT
cord-300883-rws11uel	144	14	long	long	JJ
cord-300883-rws11uel	144	15	-	-	HYPH
cord-300883-rws11uel	144	16	term	term	NN
cord-300883-rws11uel	144	17	care	care	NN
cord-300883-rws11uel	144	18	facility	facility	NN
cord-300883-rws11uel	144	19	Human	Human	NNP
cord-300883-rws11uel	144	20	metapneumovirusassociated	metapneumovirusassociate	VBD
cord-300883-rws11uel	144	21	respiratory	respiratory	JJ
cord-300883-rws11uel	144	22	tract	tract	NN
cord-300883-rws11uel	144	23	infections	infection	NNS
cord-300883-rws11uel	144	24	in	in	IN
cord-300883-rws11uel	144	25	the	the	DT
cord-300883-rws11uel	144	26	republic	republic	NN
cord-300883-rws11uel	144	27	of	of	IN
cord-300883-rws11uel	144	28	Ireland	Ireland	NNP
cord-300883-rws11uel	144	29	during	during	IN
cord-300883-rws11uel	144	30	the	the	DT
cord-300883-rws11uel	144	31	influenza	influenza	NN
cord-300883-rws11uel	144	32	season	season	NN
cord-300883-rws11uel	144	33	of	of	IN
cord-300883-rws11uel	144	34	Avian	avian	JJ
cord-300883-rws11uel	144	35	influenza	influenza	NN
cord-300883-rws11uel	144	36	virus	virus	NN
cord-300883-rws11uel	144	37	exhibits	exhibit	VBZ
cord-300883-rws11uel	144	38	rapid	rapid	JJ
cord-300883-rws11uel	144	39	evolutionary	evolutionary	JJ
cord-300883-rws11uel	144	40	dynamics	dynamic	NNS
cord-300883-rws11uel	145	1	Comparative	comparative	JJ
cord-300883-rws11uel	145	2	evaluation	evaluation	NN
cord-300883-rws11uel	145	3	of	of	IN
cord-300883-rws11uel	145	4	real	real	JJ
cord-300883-rws11uel	145	5	-	-	HYPH
cord-300883-rws11uel	145	6	time	time	NN
cord-300883-rws11uel	145	7	PCR	PCR	NNP
cord-300883-rws11uel	145	8	assays	assay	NNS
cord-300883-rws11uel	145	9	for	for	IN
cord-300883-rws11uel	145	10	detection	detection	NN
cord-300883-rws11uel	145	11	of	of	IN
cord-300883-rws11uel	145	12	the	the	DT
cord-300883-rws11uel	145	13	human	human	JJ
cord-300883-rws11uel	145	14	metapneumovirus	metapneumovirus	NN
cord-300883-rws11uel	145	15	Relaxed	relaxed	JJ
cord-300883-rws11uel	145	16	phylogenetics	phylogenetic	NNS
cord-300883-rws11uel	145	17	and	and	CC
cord-300883-rws11uel	145	18	dating	date	VBG
cord-300883-rws11uel	145	19	with	with	IN
cord-300883-rws11uel	145	20	confidence	confidence	NN
cord-300883-rws11uel	145	21	Estimating	estimating	NN
cord-300883-rws11uel	145	22	mutation	mutation	NN
cord-300883-rws11uel	145	23	parameters	parameter	NNS
cord-300883-rws11uel	145	24	,	,	,
cord-300883-rws11uel	145	25	population	population	NN
cord-300883-rws11uel	145	26	history	history	NN
cord-300883-rws11uel	145	27	,	,	,
cord-300883-rws11uel	145	28	and	and	CC
cord-300883-rws11uel	145	29	genealogy	genealogy	NN
cord-300883-rws11uel	145	30	simultaneously	simultaneously	RB
cord-300883-rws11uel	145	31	from	from	IN
cord-300883-rws11uel	145	32	temporally	temporally	RB
cord-300883-rws11uel	145	33	spaced	space	VBN
cord-300883-rws11uel	145	34	sequence	sequence	NN
cord-300883-rws11uel	145	35	data	data	NN
cord-300883-rws11uel	145	36	Bayesian	bayesian	JJ
cord-300883-rws11uel	145	37	coalescent	coalescent	JJ
cord-300883-rws11uel	145	38	inference	inference	NN
cord-300883-rws11uel	145	39	of	of	IN
cord-300883-rws11uel	145	40	past	past	JJ
cord-300883-rws11uel	145	41	population	population	NN
cord-300883-rws11uel	145	42	dynamics	dynamic	NNS
cord-300883-rws11uel	145	43	from	from	IN
cord-300883-rws11uel	145	44	molecular	molecular	JJ
cord-300883-rws11uel	145	45	sequences	sequence	NNS
cord-300883-rws11uel	145	46	Comparison	Comparison	NNP
cord-300883-rws11uel	145	47	of	of	IN
cord-300883-rws11uel	145	48	the	the	DT
cord-300883-rws11uel	145	49	seroprevalence	seroprevalence	NN
cord-300883-rws11uel	145	50	of	of	IN
cord-300883-rws11uel	145	51	human	human	JJ
cord-300883-rws11uel	145	52	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	145	53	and	and	CC
cord-300883-rws11uel	145	54	human	human	JJ
cord-300883-rws11uel	145	55	respiratory	respiratory	JJ
cord-300883-rws11uel	145	56	syncytial	syncytial	JJ
cord-300883-rws11uel	145	57	virus	virus	NN
cord-300883-rws11uel	145	58	Newer	new	JJR
cord-300883-rws11uel	145	59	respiratory	respiratory	JJ
cord-300883-rws11uel	145	60	virus	virus	NN
cord-300883-rws11uel	145	61	infections	infection	NNS
cord-300883-rws11uel	145	62	:	:	:
cord-300883-rws11uel	145	63	human	human	JJ
cord-300883-rws11uel	145	64	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	145	65	,	,	,
cord-300883-rws11uel	145	66	avian	avian	JJ
cord-300883-rws11uel	145	67	influenza	influenza	NN
cord-300883-rws11uel	145	68	,	,	,
cord-300883-rws11uel	145	69	and	and	CC
cord-300883-rws11uel	145	70	coronaviruses	coronaviruse	VBZ
cord-300883-rws11uel	145	71	Genetic	genetic	JJ
cord-300883-rws11uel	145	72	heterogeneity	heterogeneity	NN
cord-300883-rws11uel	145	73	of	of	IN
cord-300883-rws11uel	145	74	G	g	NN
cord-300883-rws11uel	145	75	and	and	CC
cord-300883-rws11uel	145	76	F	F	NNP
cord-300883-rws11uel	145	77	protein	protein	NN
cord-300883-rws11uel	145	78	genes	gene	NNS
cord-300883-rws11uel	145	79	from	from	IN
cord-300883-rws11uel	145	80	Argentinean	argentinean	JJ
cord-300883-rws11uel	145	81	human	human	JJ
cord-300883-rws11uel	145	82	metapneumovirus	metapneumovirus	NN
cord-300883-rws11uel	145	83	strains	strain	VBZ
cord-300883-rws11uel	145	84	Human	Human	NNP
cord-300883-rws11uel	145	85	metapneumovirus	metapneumovirus	JJ
cord-300883-rws11uel	145	86	Multi	Multi	NNP
cord-300883-rws11uel	145	87	-	-	JJ
cord-300883-rws11uel	145	88	year	year	JJ
cord-300883-rws11uel	145	89	study	study	NN
cord-300883-rws11uel	145	90	of	of	IN
cord-300883-rws11uel	145	91	human	human	JJ
cord-300883-rws11uel	145	92	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	145	93	infection	infection	NN
cord-300883-rws11uel	145	94	at	at	IN
cord-300883-rws11uel	145	95	a	a	DT
cord-300883-rws11uel	145	96	large	large	JJ
cord-300883-rws11uel	145	97	US	US	NNP
cord-300883-rws11uel	145	98	midwestern	midwestern	JJ
cord-300883-rws11uel	145	99	medical	medical	JJ
cord-300883-rws11uel	145	100	referral	referral	NN
cord-300883-rws11uel	145	101	center	center	NN
cord-300883-rws11uel	146	1	A	a	DT
cord-300883-rws11uel	146	2	simple	simple	JJ
cord-300883-rws11uel	146	3	,	,	,
cord-300883-rws11uel	146	4	fast	fast	JJ
cord-300883-rws11uel	146	5	,	,	,
cord-300883-rws11uel	146	6	and	and	CC
cord-300883-rws11uel	146	7	accurate	accurate	JJ
cord-300883-rws11uel	146	8	algorithm	algorithm	NN
cord-300883-rws11uel	146	9	to	to	TO
cord-300883-rws11uel	146	10	estimate	estimate	VB
cord-300883-rws11uel	146	11	large	large	JJ
cord-300883-rws11uel	146	12	phylogenies	phylogeny	NNS
cord-300883-rws11uel	146	13	by	by	IN
cord-300883-rws11uel	146	14	maximum	maximum	JJ
cord-300883-rws11uel	146	15	likelihood	likelihood	NN
cord-300883-rws11uel	147	1	BioEdit	bioedit	NN
cord-300883-rws11uel	147	2	:	:	:
cord-300883-rws11uel	147	3	a	a	DT
cord-300883-rws11uel	147	4	user	user	NN
cord-300883-rws11uel	147	5	friendly	friendly	JJ
cord-300883-rws11uel	147	6	biological	biological	JJ
cord-300883-rws11uel	147	7	sequence	sequence	NN
cord-300883-rws11uel	147	8	alignment	alignment	NN
cord-300883-rws11uel	147	9	editor	editor	NN
cord-300883-rws11uel	147	10	and	and	CC
cord-300883-rws11uel	147	11	analyses	analyse	VBZ
cord-300883-rws11uel	147	12	program	program	NN
cord-300883-rws11uel	147	13	for	for	IN
cord-300883-rws11uel	147	14	windows	window	NNS
cord-300883-rws11uel	147	15	95/98	95/98	CD
cord-300883-rws11uel	147	16	/	/	SYM
cord-300883-rws11uel	147	17	N	N	NNP
cord-300883-rws11uel	147	18	Development	Development	NNP
cord-300883-rws11uel	147	19	and	and	CC
cord-300883-rws11uel	147	20	validation	validation	NN
cord-300883-rws11uel	147	21	of	of	IN
cord-300883-rws11uel	147	22	an	an	DT
cord-300883-rws11uel	147	23	enzyme	enzyme	NN
cord-300883-rws11uel	147	24	-	-	HYPH
cord-300883-rws11uel	147	25	linked	link	VBN
cord-300883-rws11uel	147	26	immunosorbent	immunosorbent	JJ
cord-300883-rws11uel	147	27	assay	assay	NN
cord-300883-rws11uel	147	28	for	for	IN
cord-300883-rws11uel	147	29	human	human	JJ
cord-300883-rws11uel	147	30	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	147	31	serology	serology	NN
cord-300883-rws11uel	147	32	based	base	VBN
cord-300883-rws11uel	147	33	on	on	IN
cord-300883-rws11uel	147	34	a	a	DT
cord-300883-rws11uel	147	35	recombinant	recombinant	JJ
cord-300883-rws11uel	147	36	viral	viral	JJ
cord-300883-rws11uel	147	37	protein	protein	NN
cord-300883-rws11uel	147	38	Nucleotide	Nucleotide	NNP
cord-300883-rws11uel	147	39	substitution	substitution	NN
cord-300883-rws11uel	147	40	at	at	IN
cord-300883-rws11uel	147	41	major	major	JJ
cord-300883-rws11uel	147	42	histocompatibility	histocompatibility	NN
cord-300883-rws11uel	147	43	complex	complex	JJ
cord-300883-rws11uel	147	44	class	class	NN
cord-300883-rws11uel	147	45	II	ii	CD
cord-300883-rws11uel	147	46	loci	locus	NNS
cord-300883-rws11uel	147	47	:	:	:
cord-300883-rws11uel	147	48	evidence	evidence	NN
cord-300883-rws11uel	147	49	for	for	IN
cord-300883-rws11uel	147	50	overdominant	overdominant	NN
cord-300883-rws11uel	147	51	selection	selection	NN
cord-300883-rws11uel	147	52	High	high	JJ
cord-300883-rws11uel	147	53	genetic	genetic	JJ
cord-300883-rws11uel	147	54	diversity	diversity	NN
cord-300883-rws11uel	147	55	of	of	IN
cord-300883-rws11uel	147	56	the	the	DT
cord-300883-rws11uel	147	57	attachment	attachment	NN
cord-300883-rws11uel	147	58	(	(	-LRB-
cord-300883-rws11uel	147	59	G	G	NNP
cord-300883-rws11uel	147	60	)	)	-RRB-
cord-300883-rws11uel	147	61	protein	protein	NN
cord-300883-rws11uel	147	62	of	of	IN
cord-300883-rws11uel	147	63	human	human	JJ
cord-300883-rws11uel	147	64	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	147	65	Epidemiology	Epidemiology	NNP
cord-300883-rws11uel	147	66	of	of	IN
cord-300883-rws11uel	147	67	human	human	NNP
cord-300883-rws11uel	147	68	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	147	69	MEGA3	MEGA3	NNP
cord-300883-rws11uel	147	70	,	,	,
cord-300883-rws11uel	147	71	1	1	CD
cord-300883-rws11uel	147	72	:	:	SYM
cord-300883-rws11uel	147	73	integrated	integrated	JJ
cord-300883-rws11uel	147	74	software	software	NN
cord-300883-rws11uel	147	75	for	for	IN
cord-300883-rws11uel	147	76	molecular	molecular	JJ
cord-300883-rws11uel	147	77	evolutionary	evolutionary	JJ
cord-300883-rws11uel	147	78	genetics	genetics	NN
cord-300883-rws11uel	147	79	analysis	analysis	NN
cord-300883-rws11uel	147	80	and	and	CC
cord-300883-rws11uel	147	81	sequence	sequence	NN
cord-300883-rws11uel	147	82	alignment	alignment	NN
cord-300883-rws11uel	147	83	Seroepidemiology	Seroepidemiology	NNP
cord-300883-rws11uel	147	84	of	of	IN
cord-300883-rws11uel	147	85	human	human	JJ
cord-300883-rws11uel	147	86	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	147	87	(	(	-LRB-
cord-300883-rws11uel	147	88	hMPV	hMPV	NNP
cord-300883-rws11uel	147	89	)	)	-RRB-
cord-300883-rws11uel	147	90	on	on	IN
cord-300883-rws11uel	147	91	the	the	DT
cord-300883-rws11uel	147	92	basis	basis	NN
cord-300883-rws11uel	147	93	of	of	IN
cord-300883-rws11uel	147	94	a	a	DT
cord-300883-rws11uel	147	95	novel	novel	JJ
cord-300883-rws11uel	147	96	enzyme	enzyme	NN
cord-300883-rws11uel	147	97	-	-	HYPH
cord-300883-rws11uel	147	98	linked	link	VBN
cord-300883-rws11uel	147	99	immunosorbent	immunosorbent	JJ
cord-300883-rws11uel	147	100	assay	assay	NN
cord-300883-rws11uel	147	101	utilizing	utilize	VBG
cord-300883-rws11uel	147	102	hMPV	hmpv	NN
cord-300883-rws11uel	147	103	fusion	fusion	NN
cord-300883-rws11uel	147	104	protein	protein	NN
cord-300883-rws11uel	147	105	expressed	express	VBN
cord-300883-rws11uel	147	106	in	in	IN
cord-300883-rws11uel	147	107	recombinant	recombinant	JJ
cord-300883-rws11uel	147	108	vesicular	vesicular	JJ
cord-300883-rws11uel	147	109	stomatitis	stomatitis	NN
cord-300883-rws11uel	147	110	virus	virus	NN
cord-300883-rws11uel	147	111	Human	Human	NNP
cord-300883-rws11uel	147	112	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	148	1	genetic	genetic	JJ
cord-300883-rws11uel	148	2	variability	variability	NN
cord-300883-rws11uel	148	3	Molecular	molecular	JJ
cord-300883-rws11uel	148	4	assays	assay	NNS
cord-300883-rws11uel	148	5	for	for	IN
cord-300883-rws11uel	148	6	detection	detection	NN
cord-300883-rws11uel	148	7	of	of	IN
cord-300883-rws11uel	148	8	human	human	JJ
cord-300883-rws11uel	148	9	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	148	10	Mesquite	Mesquite	NNP
cord-300883-rws11uel	148	11	:	:	:
cord-300883-rws11uel	148	12	a	a	DT
cord-300883-rws11uel	148	13	modular	modular	JJ
cord-300883-rws11uel	148	14	system	system	NN
cord-300883-rws11uel	148	15	for	for	IN
cord-300883-rws11uel	148	16	evolutionary	evolutionary	JJ
cord-300883-rws11uel	148	17	analysis	analysis	NN
cord-300883-rws11uel	148	18	Real	real	JJ
cord-300883-rws11uel	148	19	-	-	HYPH
cord-300883-rws11uel	148	20	time	time	NN
cord-300883-rws11uel	148	21	reverse	reverse	NN
cord-300883-rws11uel	148	22	transcriptase	transcriptase	NN
cord-300883-rws11uel	148	23	PCR	pcr	NN
cord-300883-rws11uel	148	24	assay	assay	NN
cord-300883-rws11uel	148	25	for	for	IN
cord-300883-rws11uel	148	26	detection	detection	NN
cord-300883-rws11uel	148	27	of	of	IN
cord-300883-rws11uel	148	28	human	human	JJ
cord-300883-rws11uel	148	29	metapneumoviruses	metapneumoviruse	NNS
cord-300883-rws11uel	148	30	from	from	IN
cord-300883-rws11uel	148	31	all	all	DT
cord-300883-rws11uel	148	32	known	know	VBN
cord-300883-rws11uel	148	33	genetic	genetic	JJ
cord-300883-rws11uel	148	34	lineages	lineage	NNS
cord-300883-rws11uel	149	1	Distinct	distinct	JJ
cord-300883-rws11uel	149	2	patterns	pattern	NNS
cord-300883-rws11uel	149	3	of	of	IN
cord-300883-rws11uel	149	4	evolution	evolution	NN
cord-300883-rws11uel	149	5	between	between	IN
cord-300883-rws11uel	149	6	respiratory	respiratory	JJ
cord-300883-rws11uel	149	7	syncytial	syncytial	JJ
cord-300883-rws11uel	149	8	virus	virus	NN
cord-300883-rws11uel	149	9	subgroups	subgroup	VBZ
cord-300883-rws11uel	149	10	A	a	VBP
cord-300883-rws11uel	149	11	and	and	CC
cord-300883-rws11uel	149	12	B	b	NN
cord-300883-rws11uel	149	13	from	from	IN
cord-300883-rws11uel	149	14	New	New	NNP
cord-300883-rws11uel	149	15	Zealland	Zealland	NNP
cord-300883-rws11uel	149	16	isolates	isolate	VBZ
cord-300883-rws11uel	149	17	collected	collect	VBN
cord-300883-rws11uel	149	18	over	over	IN
cord-300883-rws11uel	149	19	thirty	thirty	CD
cord-300883-rws11uel	149	20	-	-	HYPH
cord-300883-rws11uel	149	21	seven	seven	CD
cord-300883-rws11uel	149	22	years	year	NNS
cord-300883-rws11uel	149	23	Positively	positively	RB
cord-300883-rws11uel	149	24	selected	select	VBN
cord-300883-rws11uel	149	25	codons	codon	NNS
cord-300883-rws11uel	149	26	in	in	IN
cord-300883-rws11uel	149	27	immuneexposed	immuneexpose	VBN
cord-300883-rws11uel	149	28	loops	loop	NNS
cord-300883-rws11uel	149	29	of	of	IN
cord-300883-rws11uel	149	30	the	the	DT
cord-300883-rws11uel	149	31	vaccine	vaccine	NN
cord-300883-rws11uel	149	32	candidate	candidate	NN
cord-300883-rws11uel	149	33	OMP	OMP	NNP
cord-300883-rws11uel	149	34	-	-	HYPH
cord-300883-rws11uel	149	35	P1	P1	NNP
cord-300883-rws11uel	149	36	of	of	IN
cord-300883-rws11uel	149	37	Haemophilus	Haemophilus	NNP
cord-300883-rws11uel	149	38	influenzae	influenzae	NN
cord-300883-rws11uel	149	39	Sequence	sequence	NN
cord-300883-rws11uel	149	40	polymorphism	polymorphism	NN
cord-300883-rws11uel	149	41	of	of	IN
cord-300883-rws11uel	149	42	the	the	DT
cord-300883-rws11uel	149	43	predicted	predict	VBN
cord-300883-rws11uel	149	44	human	human	JJ
cord-300883-rws11uel	149	45	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	149	46	G	G	NNP
cord-300883-rws11uel	149	47	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	149	48	Modeltest	Modeltest	NNP
cord-300883-rws11uel	149	49	:	:	:
cord-300883-rws11uel	149	50	testing	test	VBG
cord-300883-rws11uel	149	51	the	the	DT
cord-300883-rws11uel	149	52	model	model	NN
cord-300883-rws11uel	149	53	of	of	IN
cord-300883-rws11uel	149	54	DNA	dna	NN
cord-300883-rws11uel	149	55	substitution	substitution	NN
cord-300883-rws11uel	149	56	Tracer	Tracer	NNP
cord-300883-rws11uel	149	57	version	version	NN
cord-300883-rws11uel	149	58	1	1	CD
cord-300883-rws11uel	149	59	Characterization	characterization	NN
cord-300883-rws11uel	149	60	of	of	IN
cord-300883-rws11uel	149	61	human	human	JJ
cord-300883-rws11uel	149	62	metapneumovirus	metapneumovirus	JJ
cord-300883-rws11uel	149	63	infections	infection	NNS
cord-300883-rws11uel	149	64	in	in	IN
cord-300883-rws11uel	149	65	Israel	Israel	NNP
cord-300883-rws11uel	149	66	DnaSP	DnaSP	NNP
cord-300883-rws11uel	149	67	,	,	,
cord-300883-rws11uel	150	1	DNA	dna	NN
cord-300883-rws11uel	150	2	polymorphism	polymorphism	NN
cord-300883-rws11uel	150	3	analyses	analysis	NNS
cord-300883-rws11uel	150	4	by	by	IN
cord-300883-rws11uel	150	5	the	the	DT
cord-300883-rws11uel	150	6	coalescent	coalescent	JJ
cord-300883-rws11uel	150	7	and	and	CC
cord-300883-rws11uel	150	8	other	other	JJ
cord-300883-rws11uel	150	9	methods	method	NNS
cord-300883-rws11uel	151	1	The	the	DT
cord-300883-rws11uel	151	2	two	two	CD
cord-300883-rws11uel	151	3	major	major	JJ
cord-300883-rws11uel	151	4	human	human	JJ
cord-300883-rws11uel	151	5	metapneumovirus	metapneumovirus	NN
cord-300883-rws11uel	151	6	genetic	genetic	JJ
cord-300883-rws11uel	151	7	lineages	lineage	NNS
cord-300883-rws11uel	151	8	are	be	VBP
cord-300883-rws11uel	151	9	highly	highly	RB
cord-300883-rws11uel	151	10	related	relate	VBN
cord-300883-rws11uel	151	11	antigenically	antigenically	RB
cord-300883-rws11uel	151	12	,	,	,
cord-300883-rws11uel	151	13	and	and	CC
cord-300883-rws11uel	151	14	the	the	DT
cord-300883-rws11uel	151	15	fusion	fusion	NN
cord-300883-rws11uel	151	16	(	(	-LRB-
cord-300883-rws11uel	151	17	F	F	NNP
cord-300883-rws11uel	151	18	)	)	-RRB-
cord-300883-rws11uel	151	19	protein	protein	NN
cord-300883-rws11uel	151	20	is	be	VBZ
cord-300883-rws11uel	151	21	a	a	DT
cord-300883-rws11uel	151	22	major	major	JJ
cord-300883-rws11uel	151	23	contributor	contributor	NN
cord-300883-rws11uel	151	24	to	to	IN
cord-300883-rws11uel	151	25	this	this	DT
cord-300883-rws11uel	151	26	antigenic	antigenic	JJ
cord-300883-rws11uel	151	27	relatedness	relatedness	NN
cord-300883-rws11uel	151	28	Human	Human	NNP
cord-300883-rws11uel	151	29	metapneumovirus	metapneumovirus	NNP
cord-300883-rws11uel	151	30	as	as	IN
cord-300883-rws11uel	151	31	a	a	DT
cord-300883-rws11uel	151	32	cause	cause	NN
cord-300883-rws11uel	151	33	of	of	IN
cord-300883-rws11uel	151	34	community	community	NN
cord-300883-rws11uel	151	35	-	-	HYPH
cord-300883-rws11uel	151	36	acquired	acquire	VBN
cord-300883-rws11uel	151	37	respiratory	respiratory	JJ
cord-300883-rws11uel	151	38	illness	illness	NN
cord-300883-rws11uel	151	39	Pervasive	pervasive	JJ
cord-300883-rws11uel	151	40	adaptive	adaptive	JJ
cord-300883-rws11uel	151	41	evolution	evolution	NN
cord-300883-rws11uel	151	42	in	in	IN
cord-300883-rws11uel	151	43	mammalian	mammalian	JJ
cord-300883-rws11uel	151	44	fertilization	fertilization	NN
cord-300883-rws11uel	151	45	proteins	protein	NNS
cord-300883-rws11uel	151	46	Natural	natural	JJ
cord-300883-rws11uel	151	47	history	history	NN
cord-300883-rws11uel	151	48	of	of	IN
cord-300883-rws11uel	151	49	human	human	JJ
cord-300883-rws11uel	151	50	respiratory	respiratory	JJ
cord-300883-rws11uel	151	51	syncytial	syncytial	JJ
cord-300883-rws11uel	151	52	virus	virus	NN
cord-300883-rws11uel	151	53	inferred	infer	VBN
cord-300883-rws11uel	151	54	from	from	IN
cord-300883-rws11uel	151	55	phylogenetic	phylogenetic	JJ
cord-300883-rws11uel	151	56	analysis	analysis	NN
cord-300883-rws11uel	151	57	of	of	IN
cord-300883-rws11uel	151	58	the	the	DT
cord-300883-rws11uel	151	59	attachment	attachment	NN
cord-300883-rws11uel	151	60	(	(	-LRB-
cord-300883-rws11uel	151	61	G	g	NN
cord-300883-rws11uel	151	62	)	)	-RRB-
cord-300883-rws11uel	151	63	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	151	64	with	with	IN
cord-300883-rws11uel	151	65	a	a	DT
cord-300883-rws11uel	151	66	60-nucleotide	60-nucleotide	CD
cord-300883-rws11uel	151	67	duplication	duplication	NN
cord-300883-rws11uel	151	68	Isolation	isolation	NN
cord-300883-rws11uel	151	69	and	and	CC
cord-300883-rws11uel	151	70	characterization	characterization	NN
cord-300883-rws11uel	151	71	of	of	IN
cord-300883-rws11uel	151	72	monoclonal	monoclonal	JJ
cord-300883-rws11uel	151	73	antibodies	antibody	NNS
cord-300883-rws11uel	151	74	which	which	WDT
cord-300883-rws11uel	151	75	neutralize	neutralize	VBP
cord-300883-rws11uel	151	76	human	human	JJ
cord-300883-rws11uel	151	77	metapneumovirus	metapneumovirus	NN
cord-300883-rws11uel	151	78	in	in	IN
cord-300883-rws11uel	151	79	in	in	IN
cord-300883-rws11uel	151	80	vitro	vitro	FW
cord-300883-rws11uel	151	81	and	and	CC
cord-300883-rws11uel	151	82	in	in	IN
cord-300883-rws11uel	151	83	vivo	vivo	NN
cord-300883-rws11uel	152	1	A	a	DT
cord-300883-rws11uel	152	2	newly	newly	RB
cord-300883-rws11uel	152	3	discovered	discover	VBN
cord-300883-rws11uel	152	4	human	human	JJ
cord-300883-rws11uel	152	5	pneumovirus	pneumovirus	NNP
cord-300883-rws11uel	152	6	isolated	isolate	VBN
cord-300883-rws11uel	152	7	from	from	IN
cord-300883-rws11uel	152	8	young	young	JJ
cord-300883-rws11uel	152	9	children	child	NNS
cord-300883-rws11uel	152	10	with	with	IN
cord-300883-rws11uel	152	11	respiratory	respiratory	JJ
cord-300883-rws11uel	152	12	tract	tract	NN
cord-300883-rws11uel	152	13	disease	disease	NN
cord-300883-rws11uel	152	14	Increased	increase	VBD
cord-300883-rws11uel	152	15	positive	positive	JJ
cord-300883-rws11uel	152	16	selection	selection	NN
cord-300883-rws11uel	152	17	pressure	pressure	NN
cord-300883-rws11uel	152	18	in	in	IN
cord-300883-rws11uel	152	19	persistent	persistent	JJ
cord-300883-rws11uel	152	20	(	(	-LRB-
cord-300883-rws11uel	152	21	SSPE	SSPE	NNP
cord-300883-rws11uel	152	22	)	)	-RRB-
cord-300883-rws11uel	152	23	versus	versus	IN
cord-300883-rws11uel	152	24	acute	acute	JJ
cord-300883-rws11uel	152	25	measles	measle	NNS
cord-300883-rws11uel	152	26	virus	virus	NN
cord-300883-rws11uel	152	27	infections	infection	NNS
cord-300883-rws11uel	152	28	Data	Data	NNP
cord-300883-rws11uel	152	29	analysis	analysis	NN
cord-300883-rws11uel	152	30	in	in	IN
cord-300883-rws11uel	152	31	molecular	molecular	JJ
cord-300883-rws11uel	152	32	biology	biology	NN
cord-300883-rws11uel	152	33	and	and	CC
cord-300883-rws11uel	152	34	evolution	evolution	NN
cord-300883-rws11uel	152	35	DAMBE	DAMBE	NNP
cord-300883-rws11uel	152	36	:	:	:
cord-300883-rws11uel	153	1	Data	data	NN
cord-300883-rws11uel	153	2	analysis	analysis	NN
cord-300883-rws11uel	153	3	in	in	IN
cord-300883-rws11uel	153	4	molecular	molecular	JJ
cord-300883-rws11uel	153	5	biology	biology	NN
cord-300883-rws11uel	153	6	and	and	CC
cord-300883-rws11uel	153	7	evolution	evolution	NN
cord-300883-rws11uel	153	8	PAML	PAML	NNP
cord-300883-rws11uel	153	9	:	:	:
cord-300883-rws11uel	153	10	a	a	DT
cord-300883-rws11uel	153	11	program	program	NN
cord-300883-rws11uel	153	12	package	package	NN
cord-300883-rws11uel	153	13	for	for	IN
cord-300883-rws11uel	153	14	phylogenetic	phylogenetic	JJ
cord-300883-rws11uel	153	15	analysis	analysis	NN
cord-300883-rws11uel	153	16	by	by	IN
cord-300883-rws11uel	153	17	maximum	maximum	JJ
cord-300883-rws11uel	153	18	likelihood	likelihood	NN
cord-300883-rws11uel	153	19	Codon	codon	NN
cord-300883-rws11uel	153	20	-	-	HYPH
cord-300883-rws11uel	153	21	substitution	substitution	NN
cord-300883-rws11uel	153	22	models	model	NNS
cord-300883-rws11uel	153	23	for	for	IN
cord-300883-rws11uel	153	24	heterogeneous	heterogeneous	JJ
cord-300883-rws11uel	153	25	selection	selection	NN
cord-300883-rws11uel	153	26	pressures	pressure	NNS
cord-300883-rws11uel	153	27	at	at	IN
cord-300883-rws11uel	153	28	amino	amino	NN
cord-300883-rws11uel	153	29	acid	acid	NN
cord-300883-rws11uel	153	30	sites	site	NNS
cord-300883-rws11uel	154	1	Bayes	Bayes	NNP
cord-300883-rws11uel	154	2	empirical	empirical	JJ
cord-300883-rws11uel	154	3	bayes	bayes	NN
cord-300883-rws11uel	154	4	inference	inference	NN
cord-300883-rws11uel	154	5	of	of	IN
cord-300883-rws11uel	154	6	amino	amino	JJ
cord-300883-rws11uel	154	7	acid	acid	NN
cord-300883-rws11uel	154	8	sites	site	NNS
cord-300883-rws11uel	154	9	under	under	IN
cord-300883-rws11uel	154	10	positive	positive	JJ
cord-300883-rws11uel	154	11	selection	selection	NN
cord-300883-rws11uel	155	1	Adaptive	adaptive	JJ
cord-300883-rws11uel	155	2	evolution	evolution	NN
cord-300883-rws11uel	155	3	of	of	IN
cord-300883-rws11uel	155	4	the	the	DT
cord-300883-rws11uel	155	5	spike	spike	NN
cord-300883-rws11uel	155	6	gene	gene	NN
cord-300883-rws11uel	155	7	of	of	IN
cord-300883-rws11uel	155	8	SARS	SARS	NNP
cord-300883-rws11uel	155	9	coronavirus	coronavirus	NN
cord-300883-rws11uel	155	10	:	:	:
cord-300883-rws11uel	155	11	changes	change	NNS
cord-300883-rws11uel	155	12	in	in	IN
cord-300883-rws11uel	155	13	positively	positively	RB
cord-300883-rws11uel	155	14	selected	select	VBN
cord-300883-rws11uel	155	15	sites	site	NNS
cord-300883-rws11uel	155	16	in	in	IN
cord-300883-rws11uel	155	17	different	different	JJ
cord-300883-rws11uel	155	18	epidemic	epidemic	NN
cord-300883-rws11uel	155	19	groups	group	NNS
cord-300883-rws11uel	155	20	Genetic	genetic	JJ
cord-300883-rws11uel	155	21	variability	variability	NN
cord-300883-rws11uel	155	22	and	and	CC
cord-300883-rws11uel	155	23	molecular	molecular	JJ
cord-300883-rws11uel	155	24	evolution	evolution	NN
cord-300883-rws11uel	155	25	of	of	IN
cord-300883-rws11uel	155	26	the	the	DT
cord-300883-rws11uel	155	27	human	human	JJ
cord-300883-rws11uel	155	28	respiratory	respiratory	JJ
cord-300883-rws11uel	155	29	syncytial	syncytial	JJ
cord-300883-rws11uel	155	30	virus	virus	NN
cord-300883-rws11uel	155	31	subgroup	subgroup	NN
cord-300883-rws11uel	155	32	B	b	NN
cord-300883-rws11uel	155	33	attachment	attachment	NN
cord-300883-rws11uel	155	34	G	g	NN
cord-300883-rws11uel	155	35	protein	protein	NN
cord-300883-rws11uel	155	36	Molecular	molecular	JJ
cord-300883-rws11uel	155	37	evolution	evolution	NN
cord-300883-rws11uel	155	38	and	and	CC
cord-300883-rws11uel	155	39	circulation	circulation	NN
cord-300883-rws11uel	155	40	patterns	pattern	NNS
cord-300883-rws11uel	155	41	of	of	IN
cord-300883-rws11uel	155	42	human	human	JJ
cord-300883-rws11uel	155	43	respiratory	respiratory	JJ
cord-300883-rws11uel	155	44	syncytial	syncytial	JJ
cord-300883-rws11uel	155	45	virus	virus	NN
cord-300883-rws11uel	156	1	subgroup	subgroup	RB
cord-300883-rws11uel	156	2	A	A	NNP
cord-300883-rws11uel	156	3	:	:	:
cord-300883-rws11uel	156	4	Positively	positively	RB
cord-300883-rws11uel	156	5	selected	select	VBN
cord-300883-rws11uel	156	6	sites	site	NNS
cord-300883-rws11uel	156	7	in	in	IN
cord-300883-rws11uel	156	8	the	the	DT
cord-300883-rws11uel	156	9	attachment	attachment	NN
cord-300883-rws11uel	156	10	G	g	NN
cord-300883-rws11uel	156	11	glycoprotein	glycoprotein	NN
cord-300883-rws11uel	157	1	We	-PRON-	PRP
cord-300883-rws11uel	157	2	thank	thank	VBP
cord-300883-rws11uel	157	3	the	the	DT
cord-300883-rws11uel	157	4	University	University	NNP
cord-300883-rws11uel	157	5	of	of	IN
cord-300883-rws11uel	157	6	Tulsa	Tulsa	NNP
cord-300883-rws11uel	157	7	for	for	IN
cord-300883-rws11uel	157	8	providing	provide	VBG
cord-300883-rws11uel	157	9	facilities	facility	NNS
cord-300883-rws11uel	157	10	to	to	TO
cord-300883-rws11uel	157	11	carry	carry	VB
cord-300883-rws11uel	157	12	out	out	RP
cord-300883-rws11uel	157	13	this	this	DT
cord-300883-rws11uel	157	14	work	work	NN
cord-300883-rws11uel	157	15	and	and	CC
cord-300883-rws11uel	157	16	Dr.	Dr.	NNP
cord-300883-rws11uel	157	17	Peggy	Peggy	NNP
cord-300883-rws11uel	157	18	S.M.	S.M.	NNP
cord-300883-rws11uel	157	19	Hill	Hill	NNP
cord-300883-rws11uel	157	20	for	for	IN
cord-300883-rws11uel	157	21	editing	editing	NN
cord-300883-rws11uel	157	22	and	and	CC
cord-300883-rws11uel	157	23	comments	comment	NNS
cord-300883-rws11uel	157	24	for	for	IN
cord-300883-rws11uel	157	25	improving	improve	VBG
cord-300883-rws11uel	157	26	the	the	DT
cord-300883-rws11uel	157	27	manuscript	manuscript	NN
cord-300883-rws11uel	157	28	.	.	.
cord-300883-rws11uel	158	1	We	-PRON-	PRP
cord-300883-rws11uel	158	2	thank	thank	VBP
cord-300883-rws11uel	158	3	two	two	CD
cord-300883-rws11uel	158	4	anonymous	anonymous	JJ
cord-300883-rws11uel	158	5	reviewers	reviewer	NNS
cord-300883-rws11uel	158	6	for	for	IN
cord-300883-rws11uel	158	7	the	the	DT
cord-300883-rws11uel	158	8	helpful	helpful	JJ
cord-300883-rws11uel	158	9	comments	comment	NNS
cord-300883-rws11uel	158	10	on	on	IN
cord-300883-rws11uel	158	11	the	the	DT
cord-300883-rws11uel	158	12	earlier	early	JJR
cord-300883-rws11uel	158	13	version	version	NN
cord-300883-rws11uel	158	14	of	of	IN
cord-300883-rws11uel	158	15	the	the	DT
cord-300883-rws11uel	158	16	manuscript	manuscript	NN
cord-300883-rws11uel	158	17	.	.	.