id author title date pages extension mime words sentences flesch summary cache txt work_ftmr4sfzuveahklyxgbwfeyeh4 Michael Menzel Enhort: a platform for deep analysis of genomic positions 2019 13 .pdf application/pdf 5280 640 57 Keywords Virology, Data analysis, Genome annotation, Next-generation sequencing, Integration Reads containing viral integration sites are identified and sequenced in the WebLab and mapped to a reference genome. Together with genomic annotations from public database the analysis in Enhort is conducted to generated analysis of the given integration sites. be achieved in Enhort by setting the appropriate genome annotation as a covariate. MLV integration sites are compared to two different control sets: A random and an altered The upper diagram contains integration frequencies of MLV compared to random sites for a selection of annotations. MLV integration is no longer enriched but depleted in CpG islands when compared to the adapted background model. (A) Log fold changes of PB integration sites in relation to several annotations against a random and an adapted background model. We have shown that Enhort is capable of reproducing integration site analysis with less ./cache/work_ftmr4sfzuveahklyxgbwfeyeh4.pdf ./txt/work_ftmr4sfzuveahklyxgbwfeyeh4.txt