id sid tid token lemma pos work_lbjz23isnfbh5bcl4jbmahp6r4 1 1 9:7 9:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 1 2 715–723 715–723 CD work_lbjz23isnfbh5bcl4jbmahp6r4 1 3 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 1 4 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 1 5 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 1 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 1 7 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 1 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 2 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 2 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 2 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 9 copeptin copeptin NNS work_lbjz23isnfbh5bcl4jbmahp6r4 2 10 RESEARCH research VB work_lbjz23isnfbh5bcl4jbmahp6r4 2 11 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 2 12 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 13 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 14 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 2 17 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 19 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 20 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 21 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 2 22 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 23 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 2 24 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 25 Milica Milica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 27 Popovic1,2 popovic1,2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 29 Fahim Fahim NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 31 Ebrahimi1,2 ebrahimi1,2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 33 Sandrine Sandrine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 34   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 35 Andrea Andrea NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 36   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 37 Urwyler1,2 urwyler1,2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 2 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 39 Marc Marc NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 41 Yves Yves NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 42   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 43 Donath1,3 donath1,3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 2 44 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 2 45 Mirjam Mirjam NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 46   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 2 47 Christ Christ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 48 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 2 49 Crain1,2 crain1,2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 2 50 1Department 1Department NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 51 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 52 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 53 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 54 Diabetology Diabetology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 55 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 2 56 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 57 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 58 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 59 Hospital Hospital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 60 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 61 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 62 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 63 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 64 Switzerland Switzerland NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 65 2Department 2department CD work_lbjz23isnfbh5bcl4jbmahp6r4 2 66 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 67 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 68 Research Research NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 69 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 70 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 71 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 72 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 73 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 2 74 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 75 Hospital Hospital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 76 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 77 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 78 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 79 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 80 Switzerland Switzerland NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 81 3Department 3Department NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 82 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 83 Biomedicine Biomedicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 84 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 85 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 86 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 87 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 88 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 89 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 90 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 2 91 Switzerland Switzerland NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 92 Correspondence Correspondence NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 93 should should MD work_lbjz23isnfbh5bcl4jbmahp6r4 2 94 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 2 95 addressed address VBN work_lbjz23isnfbh5bcl4jbmahp6r4 2 96 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 97 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 98 Christ Christ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 99 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 2 100 Crain Crain NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 101 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 2 102 mirjam.christ-crain@usb.ch mirjam.christ-crain@usb.ch : work_lbjz23isnfbh5bcl4jbmahp6r4 2 103 Abstract Abstract NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 104 Arginine Arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 105 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 106 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 2 107 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 2 108 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 2 109 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 2 110 suggested suggest VBN work_lbjz23isnfbh5bcl4jbmahp6r4 2 111 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 2 112 contribute contribute VB work_lbjz23isnfbh5bcl4jbmahp6r4 2 113 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 114 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 2 115 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 116 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 2 117 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 118 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 2 119 diabetes diabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 2 120 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 121 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 2 122 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 2 123 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 2 124 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 2 125 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 3 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 3 2 proinflammatory proinflammatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 3 3 cytokine cytokine NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 4 interleukin interleukin NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 5 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 3 6 IL)-1 IL)-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 3 7 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 3 8 able able JJ work_lbjz23isnfbh5bcl4jbmahp6r4 3 9 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 3 10 induce induce VB work_lbjz23isnfbh5bcl4jbmahp6r4 3 11 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 3 12 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 13 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 3 14 plays play VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 3 15 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 3 16 causal causal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 3 17 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 18 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 3 19 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 3 20 mortality mortality NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 21 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 3 22 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 23 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 3 24 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 3 25 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 4 1 We -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 4 2 investigated investigate VBD work_lbjz23isnfbh5bcl4jbmahp6r4 4 3 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 4 4 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 4 5 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 4 6 whether whether IN work_lbjz23isnfbh5bcl4jbmahp6r4 4 7 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 4 8 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 4 9 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 4 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 4 11 surrogate surrogate JJ work_lbjz23isnfbh5bcl4jbmahp6r4 4 12 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 4 13 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 4 14 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 4 15 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 4 16 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 4 17 regulated regulate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 4 18 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 4 19 IL-1-mediated il-1-mediate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 4 20 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 4 21 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 4 22 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 4 23 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 4 24 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 4 25 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 4 26 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 4 27 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 5 1 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 5 2 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 5 3 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 5 4 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 5 5 prospective prospective JJ work_lbjz23isnfbh5bcl4jbmahp6r4 5 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 5 7 interventional interventional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 5 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 5 9 single single JJ work_lbjz23isnfbh5bcl4jbmahp6r4 5 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 5 11 arm arm NN work_lbjz23isnfbh5bcl4jbmahp6r4 5 12 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 5 13 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 5 14 2014–2016 2014–2016 CD work_lbjz23isnfbh5bcl4jbmahp6r4 5 15 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 5 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 6 1 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 6 2 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 6 3 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 6 4 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 6 5 randomized randomized JJ work_lbjz23isnfbh5bcl4jbmahp6r4 6 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 6 7 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 6 8 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 6 9 controlled control VBN work_lbjz23isnfbh5bcl4jbmahp6r4 6 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 6 11 double double JJ work_lbjz23isnfbh5bcl4jbmahp6r4 6 12 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 6 13 blind blind JJ work_lbjz23isnfbh5bcl4jbmahp6r4 6 14 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 6 15 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 6 16 2016–2017 2016–2017 CD work_lbjz23isnfbh5bcl4jbmahp6r4 6 17 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 6 18 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 7 1 n n LS work_lbjz23isnfbh5bcl4jbmahp6r4 7 2     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 7 3 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 7 4     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 7 5 73 73 CD work_lbjz23isnfbh5bcl4jbmahp6r4 7 6 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 7 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 7 8 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 7 9 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 10 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 7 11 n n CD work_lbjz23isnfbh5bcl4jbmahp6r4 7 12     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 7 13 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 7 14     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 7 15 66 66 CD work_lbjz23isnfbh5bcl4jbmahp6r4 7 16 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 17 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 7 18 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 7 19 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 20 adult adult NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 21 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 7 22 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 7 23 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 7 24 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 25 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 7 26 treated treat VBN work_lbjz23isnfbh5bcl4jbmahp6r4 7 27 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 7 28 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 7 29 mg mg NNS work_lbjz23isnfbh5bcl4jbmahp6r4 7 30 anakinra anakinra NNS work_lbjz23isnfbh5bcl4jbmahp6r4 7 31 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 7 32 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 33 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 34 only only RB work_lbjz23isnfbh5bcl4jbmahp6r4 7 35 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 7 36 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 37 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 38 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 39 twice twice RB work_lbjz23isnfbh5bcl4jbmahp6r4 7 40 daily daily JJ work_lbjz23isnfbh5bcl4jbmahp6r4 7 41 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 7 42 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 7 43 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 44 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 45 study study VB work_lbjz23isnfbh5bcl4jbmahp6r4 7 46 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 47 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 48 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 7 49 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 7 50 days day NNS work_lbjz23isnfbh5bcl4jbmahp6r4 7 51 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 52 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 7 53 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 7 54 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 7 55 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 8 1 Fasting fast VBG work_lbjz23isnfbh5bcl4jbmahp6r4 8 2 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 8 3 samples sample NNS work_lbjz23isnfbh5bcl4jbmahp6r4 8 4 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 8 5 drawn draw VBN work_lbjz23isnfbh5bcl4jbmahp6r4 8 6 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 8 7 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 8 8 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 8 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 8 10 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 8 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 8 12 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 8 13 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 8 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 8 15 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 8 16 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 8 17 measurement measurement NN work_lbjz23isnfbh5bcl4jbmahp6r4 8 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 8 19 serum serum NNP work_lbjz23isnfbh5bcl4jbmahp6r4 8 20 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 8 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 9 1 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 9 2 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 9 3 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 9 4 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 9 5 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 9 6 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 7 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 8 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 9 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 9 11 reactive reactive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 9 12 protein protein NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 13 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 9 14 ≥2 ≥2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 15 mg mg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 16 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 9 17 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 18 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 19 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 9 20 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 21 > > XX work_lbjz23isnfbh5bcl4jbmahp6r4 9 22 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 23 kg kg NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 24 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 9 25 m2 m2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 26 had have VBD work_lbjz23isnfbh5bcl4jbmahp6r4 9 27 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 9 28 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 9 29 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 30 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 9 31 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 32 7.7 7.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 33 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 34 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 35 4.9–11.9 4.9–11.9 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 36 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 37 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 9 38 5.8 5.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 39 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 40 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 41 3.9–9.3 3.9–9.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 42 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 43 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 44 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 9 45 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 46 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 9 47 Pinflamm Pinflamm NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 48     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 9 49 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 9 50     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 9 51 0.009 0.009 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 52 ; ; : work_lbjz23isnfbh5bcl4jbmahp6r4 9 53 7.8 7.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 54 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 55 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 56 5.4–11.7 5.4–11.7 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 57 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 58 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 9 59 4.9 4.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 60 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 61 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 62 3.7–9.8 3.7–9.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 63 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 64 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 65 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 9 66 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 9 67 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 9 68 PBMI PBMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 9 69     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 9 70 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 9 71     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 9 72 0.008 0.008 CD work_lbjz23isnfbh5bcl4jbmahp6r4 9 73 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 9 74 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 10 1 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 10 2 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 10 3 did do VBD work_lbjz23isnfbh5bcl4jbmahp6r4 10 4 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 10 5 change change VB work_lbjz23isnfbh5bcl4jbmahp6r4 10 6 either either CC work_lbjz23isnfbh5bcl4jbmahp6r4 10 7 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 10 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 10 9 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 10 10 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 10 11 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 10 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 10 13 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 10 14 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 10 15 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 10 16 remained remain VBD work_lbjz23isnfbh5bcl4jbmahp6r4 10 17 stable stable JJ work_lbjz23isnfbh5bcl4jbmahp6r4 10 18 throughout throughout IN work_lbjz23isnfbh5bcl4jbmahp6r4 10 19 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 10 20 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 10 21 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 10 22 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 10 23     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 10 24 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 10 25     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 10 26 0.44 0.44 CD work_lbjz23isnfbh5bcl4jbmahp6r4 10 27 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 10 28 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 11 1 Subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 11 2 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 11 3 did do VBD work_lbjz23isnfbh5bcl4jbmahp6r4 11 4 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 11 5 reveal reveal VB work_lbjz23isnfbh5bcl4jbmahp6r4 11 6 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 11 7 modifications modification NNS work_lbjz23isnfbh5bcl4jbmahp6r4 11 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 12 1 Therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 12 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 12 3 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 12 4 conclude conclude VBP work_lbjz23isnfbh5bcl4jbmahp6r4 12 5 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 12 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 12 7 although although IN work_lbjz23isnfbh5bcl4jbmahp6r4 12 8 IL-1-mediated il-1-mediated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 12 9 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 12 10 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 12 11 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 12 12 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 12 13 increased increase VBN work_lbjz23isnfbh5bcl4jbmahp6r4 12 14 circulating circulate VBG work_lbjz23isnfbh5bcl4jbmahp6r4 12 15 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 12 16 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 12 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 12 18 antagonizing antagonize VBG work_lbjz23isnfbh5bcl4jbmahp6r4 12 19 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 12 20 does do VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 12 21 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 12 22 significantly significantly RB work_lbjz23isnfbh5bcl4jbmahp6r4 12 23 alter alter VB work_lbjz23isnfbh5bcl4jbmahp6r4 12 24 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 12 25 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 12 26 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 12 27 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 12 28 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 12 29 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 12 30 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 12 31 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 13 1 Introduction introduction NN work_lbjz23isnfbh5bcl4jbmahp6r4 13 2 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 13 3 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 13 4 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 13 5 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 13 6 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 13 7 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 13 8 significant significant JJ work_lbjz23isnfbh5bcl4jbmahp6r4 13 9 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 13 10 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 13 11 developing develop VBG work_lbjz23isnfbh5bcl4jbmahp6r4 13 12 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 13 13 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 13 14 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 13 15 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 13 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 13 17 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 13 18 diseases disease NNS work_lbjz23isnfbh5bcl4jbmahp6r4 13 19 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 13 20 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 13 21 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 13 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 14 1 Arginine Arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 14 2 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 3 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 14 4 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 14 5 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 14 6 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 14 7 suggested suggest VBN work_lbjz23isnfbh5bcl4jbmahp6r4 14 8 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 14 9 play play VB work_lbjz23isnfbh5bcl4jbmahp6r4 14 10 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 14 11 causal causal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 14 12 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 14 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 14 15 development development NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 14 17 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 18 2 2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 14 19 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 20 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 21 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 14 22 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 14 23 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 14 24 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 14 25 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 14 26 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 14 27 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 15 1 Indeed indeed RB work_lbjz23isnfbh5bcl4jbmahp6r4 15 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 3 several several JJ work_lbjz23isnfbh5bcl4jbmahp6r4 15 4 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 15 5 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 15 6 demonstrated demonstrate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 15 7 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 8 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 9 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 15 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 15 11 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 15 12 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 15 13 terminal terminal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 15 14 part part NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 15 17 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 15 18 precursor precursor NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 19 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 15 20 surrogate surrogate JJ work_lbjz23isnfbh5bcl4jbmahp6r4 15 21 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 22 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 23 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 15 24 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 15 25 3 3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 26 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 15 27 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 15 28 predicts predict VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 15 29 insulin insulin VBP work_lbjz23isnfbh5bcl4jbmahp6r4 15 30 resistance resistance NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 31 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 15 32 onset onset NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 33 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 34 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 35 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 36 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 37 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 38 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 15 39 4 4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 40 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 41 5 5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 42 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 43 6 6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 44 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 45 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 46 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 47 8 8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 48 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 49 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 50 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 51 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 52 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 15 53 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 15 54 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 15 55 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 15 56 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 57 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 15 58 increased increase VBN work_lbjz23isnfbh5bcl4jbmahp6r4 15 59 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 15 60 mortality mortality NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 61 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 62 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 15 63 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 15 64 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 15 65 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 15 66 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 15 67 5 5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 68 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 69 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 70 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 71 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 72 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 15 73 13 13 CD work_lbjz23isnfbh5bcl4jbmahp6r4 15 74 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 15 75 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 16 1 There there EX work_lbjz23isnfbh5bcl4jbmahp6r4 16 2 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 16 3 several several JJ work_lbjz23isnfbh5bcl4jbmahp6r4 16 4 potential potential JJ work_lbjz23isnfbh5bcl4jbmahp6r4 16 5 pathways pathway NNS work_lbjz23isnfbh5bcl4jbmahp6r4 16 6 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 16 7 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 16 8 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 16 9 might may MD work_lbjz23isnfbh5bcl4jbmahp6r4 16 10 mediate mediate VB work_lbjz23isnfbh5bcl4jbmahp6r4 16 11 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 16 12 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 16 13 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 16 14 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 16 15 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 16 16 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 16 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 17 1 First first RB work_lbjz23isnfbh5bcl4jbmahp6r4 17 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 17 3 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 4 leads lead VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 17 5 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 6 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 17 7 amplification amplification NN work_lbjz23isnfbh5bcl4jbmahp6r4 17 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 9 cortisol cortisol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 10 release release NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 11 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 12 inhibiting inhibit VBG work_lbjz23isnfbh5bcl4jbmahp6r4 17 13 negative negative JJ work_lbjz23isnfbh5bcl4jbmahp6r4 17 14 feedback feedback NN work_lbjz23isnfbh5bcl4jbmahp6r4 17 15 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 16 adrenocorticotropic adrenocorticotropic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 17 17 hormone hormone NN work_lbjz23isnfbh5bcl4jbmahp6r4 17 18 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 17 19 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 20 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 17 21 anterior anterior NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 22 pituitary pituitary NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 23 gland gland NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 24 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 17 25 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 26 direct direct JJ work_lbjz23isnfbh5bcl4jbmahp6r4 17 27 stimulation stimulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 17 28 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 17 29 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 17 30 adrenal adrenal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 17 31 cortex cortex NNP work_lbjz23isnfbh5bcl4jbmahp6r4 17 32 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 17 33 14 14 CD work_lbjz23isnfbh5bcl4jbmahp6r4 17 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 17 35 15 15 CD work_lbjz23isnfbh5bcl4jbmahp6r4 17 36 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 17 37 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 18 1 Moreover moreover RB work_lbjz23isnfbh5bcl4jbmahp6r4 18 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 18 3 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 18 4 induces induce VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 18 5 epinephrine epinephrine VBP work_lbjz23isnfbh5bcl4jbmahp6r4 18 6 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 7 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 18 8 stimulation stimulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 18 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 18 11 chromaffin chromaffin NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 12 cells cell NNS work_lbjz23isnfbh5bcl4jbmahp6r4 18 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 18 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 18 15 adrenal adrenal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 18 16 medulla medulla NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 18 18 16 16 CD work_lbjz23isnfbh5bcl4jbmahp6r4 18 19 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 18 20 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 18 21 stimulates stimulate VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 18 22 glycogenolysis glycogenolysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 23 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 18 24 gluconeogenesis gluconeogenesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 25 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 18 26 V1a V1a NNP work_lbjz23isnfbh5bcl4jbmahp6r4 18 27 receptors receptor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 18 28 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 18 29 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 18 30 liver liver NN work_lbjz23isnfbh5bcl4jbmahp6r4 18 31 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 18 32 17 17 CD work_lbjz23isnfbh5bcl4jbmahp6r4 18 33 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 18 34 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 19 1 Furthermore furthermore RB work_lbjz23isnfbh5bcl4jbmahp6r4 19 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 19 3 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 19 4 has have VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 19 5 antilipolytic antilipolytic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 19 6 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 19 7 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 19 8 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 19 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 19 10 prothrombotic prothrombotic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 19 11 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 19 12 19 19 CD work_lbjz23isnfbh5bcl4jbmahp6r4 19 13 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 19 14 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 19 15 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 19 16 mediates mediate VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 19 17 coronary coronary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 19 18 vasoconstriction vasoconstriction NN work_lbjz23isnfbh5bcl4jbmahp6r4 19 19 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 19 20 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 19 21 1a 1a NNP work_lbjz23isnfbh5bcl4jbmahp6r4 19 22 receptors receptor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 19 23 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 19 24 20 20 CD work_lbjz23isnfbh5bcl4jbmahp6r4 19 25 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 19 26 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 20 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 20 2 mechanisms mechanism NNS work_lbjz23isnfbh5bcl4jbmahp6r4 20 3 underlying underlie VBG work_lbjz23isnfbh5bcl4jbmahp6r4 20 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 20 5 upregulation upregulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 20 6 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 20 7 AVP/ AVP/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 20 8 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 20 9 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 20 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 20 11 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 20 12 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 20 13 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 20 14 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 20 15 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 20 16 unknown unknown JJ work_lbjz23isnfbh5bcl4jbmahp6r4 20 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 21 1 Interestingly interestingly RB work_lbjz23isnfbh5bcl4jbmahp6r4 21 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 21 3 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 21 4 seems seem VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 21 5 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 21 6 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 21 7 strongly strongly RB work_lbjz23isnfbh5bcl4jbmahp6r4 21 8 -20 -20 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 9 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 21 10 0197 0197 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 11 Key Key NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 12 Words Words NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 21 13 f f NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 14 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 21 15 syndrome syndrome NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 16 f f NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 17 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 18 f f NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 19 arginine arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 20 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 21 f f NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 22 interleukin-1 interleukin-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 23 f f NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 24 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 21 25 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 21 26 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 21 27 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 21 28 Endocrine Endocrine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 29 Connections Connections NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 21 30 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 21 31 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 32 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 21 33 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 21 35 715–723 715–723 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 36 ID ID NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 37 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 21 38 20 20 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 39 - - SYM work_lbjz23isnfbh5bcl4jbmahp6r4 21 40 0197 0197 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 41 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 42 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 43 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 21 44 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 21 45 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 21 46 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 21 47 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 21 48 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 21 49 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 50 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 51 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 52 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 21 53 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 54 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 55 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 56 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 57 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 21 58 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 59 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 60 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 21 61 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 21 62 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 21 63 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 21 64 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 65 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 66 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 21 67 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 21 68 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 69 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 21 70 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 21 71 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 72 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 21 73 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 21 74 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 21 75 mailto:mirjam.christ-crain@usb.ch mailto:mirjam.christ-crain@usb.ch IN work_lbjz23isnfbh5bcl4jbmahp6r4 21 76 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 77 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 78 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 79 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 80 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 81 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 82 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 83   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 21 84 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 21 85 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 22 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 22 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 22 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 22 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 22 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 22 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 22 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 22 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 22 9 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 22 10 716 716 CD work_lbjz23isnfbh5bcl4jbmahp6r4 22 11 PB PB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 22 12 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 22 13 XX XX NNP work_lbjz23isnfbh5bcl4jbmahp6r4 22 14 9:7 9:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 22 15 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 22 16 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 22 17 elevated elevated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 22 18 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 22 19 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 22 20 C c NN work_lbjz23isnfbh5bcl4jbmahp6r4 22 21 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 22 22 reactive reactive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 22 23 protein protein NN work_lbjz23isnfbh5bcl4jbmahp6r4 22 24 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 22 25 CRP crp NN work_lbjz23isnfbh5bcl4jbmahp6r4 22 26 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 22 27 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 22 28 8 8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 22 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 22 30 21 21 CD work_lbjz23isnfbh5bcl4jbmahp6r4 22 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 22 32 22 22 CD work_lbjz23isnfbh5bcl4jbmahp6r4 22 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 22 34 23 23 CD work_lbjz23isnfbh5bcl4jbmahp6r4 22 35 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 22 36 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 23 1 Elevated elevated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 23 2 CRP crp NN work_lbjz23isnfbh5bcl4jbmahp6r4 23 3 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 23 4 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 23 5 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 23 6 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 23 7 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 23 8 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 23 9 result result VBP work_lbjz23isnfbh5bcl4jbmahp6r4 23 10 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 23 11 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 23 12 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 23 13 activation activation NN work_lbjz23isnfbh5bcl4jbmahp6r4 23 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 23 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 23 16 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 23 17 system system NN work_lbjz23isnfbh5bcl4jbmahp6r4 23 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 23 19 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 23 20 key key JJ work_lbjz23isnfbh5bcl4jbmahp6r4 23 21 cytokine cytokine NN work_lbjz23isnfbh5bcl4jbmahp6r4 23 22 stimulated stimulate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 23 23 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 23 24 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 23 25 stress stress NN work_lbjz23isnfbh5bcl4jbmahp6r4 23 26 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 23 27 24 24 CD work_lbjz23isnfbh5bcl4jbmahp6r4 23 28 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 23 29 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 24 1 Chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 24 2 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 24 3 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 24 4 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 5 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 6 enacted enact VBN work_lbjz23isnfbh5bcl4jbmahp6r4 24 7 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 24 8 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 24 9 activity activity NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 10 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 24 11 recently recently RB work_lbjz23isnfbh5bcl4jbmahp6r4 24 12 shown show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 24 13 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 24 14 play play VB work_lbjz23isnfbh5bcl4jbmahp6r4 24 15 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 24 16 causal causal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 24 17 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 18 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 24 19 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 24 20 development development NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 21 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 24 22 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 24 23 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 24 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 24 25 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 26 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 27 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 24 28 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 24 29 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 24 30 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 25 1 Randomized randomized JJ work_lbjz23isnfbh5bcl4jbmahp6r4 25 2 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 3 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 25 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 25 5 antagonists antagonist NNS work_lbjz23isnfbh5bcl4jbmahp6r4 25 6 has have VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 25 7 proven prove VBN work_lbjz23isnfbh5bcl4jbmahp6r4 25 8 capacity capacity NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 9 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 25 10 reduce reduce VB work_lbjz23isnfbh5bcl4jbmahp6r4 25 11 HbA1c HbA1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 25 12 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 25 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 25 14 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 25 15 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 25 16 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 17 2 2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 25 18 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 19 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 20 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 25 21 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 25 22 reduce reduce VB work_lbjz23isnfbh5bcl4jbmahp6r4 25 23 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 25 24 mortality mortality NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 25 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 25 26 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 25 27 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 25 28 coronary coronary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 25 29 heart heart NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 30 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 25 31 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 25 32 elevated elevated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 25 33 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 25 34 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 25 35 CRP CRP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 25 36 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 25 37 25 25 CD work_lbjz23isnfbh5bcl4jbmahp6r4 25 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 25 39 26 26 CD work_lbjz23isnfbh5bcl4jbmahp6r4 25 40 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 25 41 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 26 1 Interestingly interestingly RB work_lbjz23isnfbh5bcl4jbmahp6r4 26 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 26 3 there there EX work_lbjz23isnfbh5bcl4jbmahp6r4 26 4 seems seem VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 26 5 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 26 6 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 26 7 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 26 8 interplay interplay NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 9 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 10 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 26 11 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 26 12 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 26 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 26 14 since since IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 15 animal animal NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 16 experiments experiment NNS work_lbjz23isnfbh5bcl4jbmahp6r4 26 17 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 26 18 shown show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 26 19 induction induction NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 20 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 21 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 26 22 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 23 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 24 response response NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 25 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 26 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 26 27 application application NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 28 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 26 29 27 27 CD work_lbjz23isnfbh5bcl4jbmahp6r4 26 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 26 31 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 26 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 26 33 29 29 CD work_lbjz23isnfbh5bcl4jbmahp6r4 26 34 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 26 35 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 26 36 although although IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 37 there there EX work_lbjz23isnfbh5bcl4jbmahp6r4 26 38 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 26 39 conflicting conflict VBG work_lbjz23isnfbh5bcl4jbmahp6r4 26 40 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 26 41 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 42 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 26 43 rat rat NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 44 model model NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 45 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 26 46 sepsis sepsis NN work_lbjz23isnfbh5bcl4jbmahp6r4 26 47 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 26 48 30 30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 26 49 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 26 50 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 27 1 We -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 27 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 27 3 therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 27 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 27 5 hypothesize hypothesize VB work_lbjz23isnfbh5bcl4jbmahp6r4 27 6 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 27 8 increased increase VBN work_lbjz23isnfbh5bcl4jbmahp6r4 27 9 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 27 10 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 11 copeptin copeptin NNS work_lbjz23isnfbh5bcl4jbmahp6r4 27 12 observed observe VBN work_lbjz23isnfbh5bcl4jbmahp6r4 27 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 14 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 27 15 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 16 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 27 17 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 27 18 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 27 19 caused cause VBN work_lbjz23isnfbh5bcl4jbmahp6r4 27 20 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 21 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 27 22 overactivity overactivity NN work_lbjz23isnfbh5bcl4jbmahp6r4 27 23 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 24 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 27 25 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 27 26 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 27 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 27 28 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 29 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 27 30 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 27 31 pathway pathway NN work_lbjz23isnfbh5bcl4jbmahp6r4 27 32 would would MD work_lbjz23isnfbh5bcl4jbmahp6r4 27 33 lead lead VB work_lbjz23isnfbh5bcl4jbmahp6r4 27 34 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 35 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 27 36 reduction reduction NN work_lbjz23isnfbh5bcl4jbmahp6r4 27 37 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 27 38 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 27 39 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 27 40 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 28 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 28 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 28 3 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 28 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 28 5 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 28 6 report report VBP work_lbjz23isnfbh5bcl4jbmahp6r4 28 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 28 8 results result NNS work_lbjz23isnfbh5bcl4jbmahp6r4 28 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 28 10 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 28 11 interventional interventional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 28 12 trials trial NNS work_lbjz23isnfbh5bcl4jbmahp6r4 28 13 investigating investigate VBG work_lbjz23isnfbh5bcl4jbmahp6r4 28 14 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 28 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 28 16 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 28 17 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 28 18 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 28 19 obese obese JJ work_lbjz23isnfbh5bcl4jbmahp6r4 28 20 individuals individual NNS work_lbjz23isnfbh5bcl4jbmahp6r4 28 21 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 28 22 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 28 23 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 28 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 29 1 Methods method NNS work_lbjz23isnfbh5bcl4jbmahp6r4 29 2 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 29 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 29 4 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 29 5 preplanned preplanne VBN work_lbjz23isnfbh5bcl4jbmahp6r4 29 6 secondary secondary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 29 7 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 29 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 29 9 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 29 10 interventional interventional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 29 11 trials trial NNS work_lbjz23isnfbh5bcl4jbmahp6r4 29 12 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 29 13 31 31 CD work_lbjz23isnfbh5bcl4jbmahp6r4 29 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 29 15 32 32 CD work_lbjz23isnfbh5bcl4jbmahp6r4 29 16 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 29 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 30 1 Both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 30 2 trials trial NNS work_lbjz23isnfbh5bcl4jbmahp6r4 30 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 30 4 conducted conduct VBN work_lbjz23isnfbh5bcl4jbmahp6r4 30 5 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 30 6 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 30 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 30 8 ethical ethical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 30 9 guidelines guideline NNS work_lbjz23isnfbh5bcl4jbmahp6r4 30 10 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 30 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 30 12 Declaration Declaration NNP work_lbjz23isnfbh5bcl4jbmahp6r4 30 13 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 30 14 Helsinki Helsinki NNP work_lbjz23isnfbh5bcl4jbmahp6r4 30 15 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 30 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 30 17 applicable applicable JJ work_lbjz23isnfbh5bcl4jbmahp6r4 30 18 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 30 19 Conference Conference NNP work_lbjz23isnfbh5bcl4jbmahp6r4 30 20 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 30 21 Harmonization Harmonization NNP work_lbjz23isnfbh5bcl4jbmahp6r4 30 22 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 30 23 ICH ICH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 30 24 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 30 25 guidelines guideline NNS work_lbjz23isnfbh5bcl4jbmahp6r4 30 26 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 30 27 good good JJ work_lbjz23isnfbh5bcl4jbmahp6r4 30 28 clinical clinical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 30 29 practice practice NN work_lbjz23isnfbh5bcl4jbmahp6r4 30 30 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 31 1 Both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 31 2 trials trial NNS work_lbjz23isnfbh5bcl4jbmahp6r4 31 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 31 4 approved approve VBN work_lbjz23isnfbh5bcl4jbmahp6r4 31 5 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 31 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 31 7 Ethics Ethics NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 8 Committee Committee NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 9 Northwest Northwest NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 10 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 31 11 Central Central NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 12 Switzerland Switzerland NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 13 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 31 14 EKNZ EKNZ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 15 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 31 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 31 17 Swissmedic Swissmedic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 31 19 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 31 20 registered register VBN work_lbjz23isnfbh5bcl4jbmahp6r4 31 21 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 31 22 ClinicalTrials.gov ClinicalTrials.gov NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 23 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 31 24 NCT00757276 NCT00757276 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 31 26 NCT02672592 NCT02672592 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 31 27 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 31 28 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 32 1 All all DT work_lbjz23isnfbh5bcl4jbmahp6r4 32 2 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 32 3 provided provide VBD work_lbjz23isnfbh5bcl4jbmahp6r4 32 4 written write VBN work_lbjz23isnfbh5bcl4jbmahp6r4 32 5 informed informed JJ work_lbjz23isnfbh5bcl4jbmahp6r4 32 6 consent consent NN work_lbjz23isnfbh5bcl4jbmahp6r4 32 7 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 33 1 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 33 2 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 33 3 recruited recruit VBN work_lbjz23isnfbh5bcl4jbmahp6r4 33 4 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 33 5 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 33 6 tertiary tertiary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 33 7 care care NN work_lbjz23isnfbh5bcl4jbmahp6r4 33 8 centers center NNS work_lbjz23isnfbh5bcl4jbmahp6r4 33 9 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 33 10 Switzerland Switzerland NNP work_lbjz23isnfbh5bcl4jbmahp6r4 33 11 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 33 12 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 33 13 Hospital Hospital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 33 14 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 33 15 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 33 16 Kantonsspital Kantonsspital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 33 17 Aarau Aarau NNP work_lbjz23isnfbh5bcl4jbmahp6r4 33 18 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 33 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 34 1 Study study VB work_lbjz23isnfbh5bcl4jbmahp6r4 34 2 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 3 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 34 4 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 34 5 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 34 6 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 7 design design NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 8 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 34 9 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 34 10 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 34 11 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 34 12 prospective prospective JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 34 14 open open JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 15 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 34 16 labeled labeled JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 34 18 interventional interventional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 19 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 20 investigating investigate VBG work_lbjz23isnfbh5bcl4jbmahp6r4 34 21 short short JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 22 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 34 23 term term NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 24 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 34 25 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 34 26 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 34 27 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 28 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 34 29 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 34 30 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 34 31 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 32 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 33 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 34 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 34 35 73 73 CD work_lbjz23isnfbh5bcl4jbmahp6r4 34 36 obese obese JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 37 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 34 38 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 34 39 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 34 40 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 34 41 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 35 1 Detailed detailed JJ work_lbjz23isnfbh5bcl4jbmahp6r4 35 2 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 35 3 procedures procedure NNS work_lbjz23isnfbh5bcl4jbmahp6r4 35 4 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 35 5 been be VBN work_lbjz23isnfbh5bcl4jbmahp6r4 35 6 published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 35 7 previously previously RB work_lbjz23isnfbh5bcl4jbmahp6r4 35 8 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 35 9 32 32 CD work_lbjz23isnfbh5bcl4jbmahp6r4 35 10 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 35 11 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 36 1 Briefly briefly RB work_lbjz23isnfbh5bcl4jbmahp6r4 36 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 36 3 inclusion inclusion NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 4 criteria criterion NNS work_lbjz23isnfbh5bcl4jbmahp6r4 36 5 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 36 6 age age NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 7 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 36 8 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 10 80 80 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 11 years year NNS work_lbjz23isnfbh5bcl4jbmahp6r4 36 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 36 13 body body NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 36 15 mass mass NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 16 index index NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 18 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 19 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 20 > > NFP work_lbjz23isnfbh5bcl4jbmahp6r4 36 21 30 30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 22 kg kg NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 23 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 36 24 m2 m2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 25 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 26 at at RB work_lbjz23isnfbh5bcl4jbmahp6r4 36 27 least least JJS work_lbjz23isnfbh5bcl4jbmahp6r4 36 28 one one CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 29 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 36 30 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 36 31 following follow VBG work_lbjz23isnfbh5bcl4jbmahp6r4 36 32 additional additional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 36 33 features feature NNS work_lbjz23isnfbh5bcl4jbmahp6r4 36 34 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 36 35 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 36 36 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 36 37 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 38 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 36 39 Hyperglycemia hyperglycemia NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 40 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 41 HbA1c HbA1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 42 > > NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 43 5.7 5.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 44 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 45 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 46 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 36 47 hypertension hypertension NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 48 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 49 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 50 pressure pressure NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 51 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 52 BP BP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 53 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 54 > > XX work_lbjz23isnfbh5bcl4jbmahp6r4 36 55 130/85 130/85 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 56 mmHg mmhg CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 57 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 58 BP BP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 59 lowering lower VBG work_lbjz23isnfbh5bcl4jbmahp6r4 36 60 therapy therapy NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 61 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 62 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 36 63 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 64 dyslipidemia dyslipidemia NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 65 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 66 HDL HDL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 67 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 36 68 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 69 < < XX work_lbjz23isnfbh5bcl4jbmahp6r4 36 70 1.0 1.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 71 mmol mmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 72 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 36 73 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 74 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 75 triglycerides triglyceride NNS work_lbjz23isnfbh5bcl4jbmahp6r4 36 76 > > XX work_lbjz23isnfbh5bcl4jbmahp6r4 36 77 1.7 1.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 78 mmol mmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 79 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 36 80 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 81 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 82 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 36 83 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 36 84 density density NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 85 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 36 86 lipoprotein- lipoprotein- NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 87 cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 88 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 89 LDL LDL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 90 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 36 91 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 36 92 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 93 > > XX work_lbjz23isnfbh5bcl4jbmahp6r4 36 94 3.4 3.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 36 95 mmol mmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 96 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 36 97 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 98 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 36 99 lipid lipid NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 100 lowering lowering NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 101 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 36 102 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 36 103 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 37 1 Main main JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 2 exclusion exclusion NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 3 criteria criterion NNS work_lbjz23isnfbh5bcl4jbmahp6r4 37 4 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 37 5 concurrent concurrent JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 6 medication medication NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 7 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 37 8 glucocorticoids glucocorticoid NNS work_lbjz23isnfbh5bcl4jbmahp6r4 37 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 37 10 known know VBN work_lbjz23isnfbh5bcl4jbmahp6r4 37 11 Cushing Cushing NNP work_lbjz23isnfbh5bcl4jbmahp6r4 37 12 ’s ’s POS work_lbjz23isnfbh5bcl4jbmahp6r4 37 13 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 37 15 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 37 16 underlying underlie VBG work_lbjz23isnfbh5bcl4jbmahp6r4 37 17 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 18 inflammatory inflammatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 19 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 37 21 history history NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 22 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 37 23 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 37 24 severe severe JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 25 infection infection NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 26 within within IN work_lbjz23isnfbh5bcl4jbmahp6r4 37 27 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 37 28 previous previous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 29 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 37 30 months month NNS work_lbjz23isnfbh5bcl4jbmahp6r4 37 31 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 37 32 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 37 33 current current JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 34 infection infection NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 35 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 37 36 severe severe JJ work_lbjz23isnfbh5bcl4jbmahp6r4 37 37 comorbidities comorbiditie NNS work_lbjz23isnfbh5bcl4jbmahp6r4 37 38 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 37 39 pregnancy pregnancy NN work_lbjz23isnfbh5bcl4jbmahp6r4 37 40 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 37 41 breastfeeding breastfeed VBG work_lbjz23isnfbh5bcl4jbmahp6r4 37 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 38 1 After after IN work_lbjz23isnfbh5bcl4jbmahp6r4 38 2 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 38 3 screening screening NN work_lbjz23isnfbh5bcl4jbmahp6r4 38 4 visit visit NN work_lbjz23isnfbh5bcl4jbmahp6r4 38 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 38 6 all all DT work_lbjz23isnfbh5bcl4jbmahp6r4 38 7 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 38 8 received receive VBD work_lbjz23isnfbh5bcl4jbmahp6r4 38 9 three three CD work_lbjz23isnfbh5bcl4jbmahp6r4 38 10 s.c s.c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 38 11 . . NNP work_lbjz23isnfbh5bcl4jbmahp6r4 38 12 injections injection NNS work_lbjz23isnfbh5bcl4jbmahp6r4 38 13 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 38 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 38 15 recombinant recombinant JJ work_lbjz23isnfbh5bcl4jbmahp6r4 38 16 human human JJ work_lbjz23isnfbh5bcl4jbmahp6r4 38 17 interleukin-1-receptor interleukin-1-receptor NNP work_lbjz23isnfbh5bcl4jbmahp6r4 38 18 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 38 19 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 38 20 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 38 21 Kineret Kineret NNP work_lbjz23isnfbh5bcl4jbmahp6r4 38 22 ® ® NNP work_lbjz23isnfbh5bcl4jbmahp6r4 38 23 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 38 24 mg mg CD work_lbjz23isnfbh5bcl4jbmahp6r4 38 25 within within IN work_lbjz23isnfbh5bcl4jbmahp6r4 38 26 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 38 27 days day NNS work_lbjz23isnfbh5bcl4jbmahp6r4 38 28 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 39 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 39 2 consecutive consecutive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 39 3 injections injection NNS work_lbjz23isnfbh5bcl4jbmahp6r4 39 4 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 39 5 started start VBN work_lbjz23isnfbh5bcl4jbmahp6r4 39 6 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 39 7 20:00 20:00 CD work_lbjz23isnfbh5bcl4jbmahp6r4 39 8 h h NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 39 10 continued continue VBD work_lbjz23isnfbh5bcl4jbmahp6r4 39 11 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 39 12 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 39 13 time time NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 14 interval interval NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 39 16 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 39 17 h. h. NNS work_lbjz23isnfbh5bcl4jbmahp6r4 39 18 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 39 19 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 20 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 39 21 visits visit NNS work_lbjz23isnfbh5bcl4jbmahp6r4 39 22 assessed assess VBN work_lbjz23isnfbh5bcl4jbmahp6r4 39 23 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 39 24 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 39 25 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 26 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 39 27 ‘ ' `` work_lbjz23isnfbh5bcl4jbmahp6r4 39 28 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 39 29 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 39 30 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 39 31 = = NFP work_lbjz23isnfbh5bcl4jbmahp6r4 39 32 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 39 33 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 34 0 0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 39 35 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 39 36 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 39 37 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 39 38 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 39 39 three three CD work_lbjz23isnfbh5bcl4jbmahp6r4 39 40 injections injection NNS work_lbjz23isnfbh5bcl4jbmahp6r4 39 41 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 39 42 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 39 43 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 39 44 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 45 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 39 46 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 39 47 Kineret Kineret NNP work_lbjz23isnfbh5bcl4jbmahp6r4 39 48 ® ® , work_lbjz23isnfbh5bcl4jbmahp6r4 39 49 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 39 50 = = NFP work_lbjz23isnfbh5bcl4jbmahp6r4 39 51 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 39 52 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 39 53 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 39 54 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 39 55 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 39 56 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 40 1 Study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 40 2 visits visit NNS work_lbjz23isnfbh5bcl4jbmahp6r4 40 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 40 4 scheduled schedule VBN work_lbjz23isnfbh5bcl4jbmahp6r4 40 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 40 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 40 7 morning morning NN work_lbjz23isnfbh5bcl4jbmahp6r4 40 8 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 40 9 07:30 07:30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 40 10 h h NN work_lbjz23isnfbh5bcl4jbmahp6r4 40 11 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 40 12 10:00 10:00 CD work_lbjz23isnfbh5bcl4jbmahp6r4 40 13 h h NN work_lbjz23isnfbh5bcl4jbmahp6r4 40 14 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 40 15 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 40 16 overnight overnight JJ work_lbjz23isnfbh5bcl4jbmahp6r4 40 17 fast fast NN work_lbjz23isnfbh5bcl4jbmahp6r4 40 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 40 19 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 40 20 samples sample NNS work_lbjz23isnfbh5bcl4jbmahp6r4 40 21 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 40 22 drawn draw VBN work_lbjz23isnfbh5bcl4jbmahp6r4 40 23 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 40 24 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 40 25 visits visit NNS work_lbjz23isnfbh5bcl4jbmahp6r4 40 26 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 41 1 Study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 2 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 41 3 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 41 4 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 41 5 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 41 6 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 7 design design NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 8 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 41 9 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 41 10 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 41 11 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 41 12 randomized randomized JJ work_lbjz23isnfbh5bcl4jbmahp6r4 41 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 41 14 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 15 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 41 16 controlled control VBN work_lbjz23isnfbh5bcl4jbmahp6r4 41 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 41 18 double- double- VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 41 19 blind blind JJ work_lbjz23isnfbh5bcl4jbmahp6r4 41 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 41 21 interventional interventional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 41 22 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 23 investigating investigate VBG work_lbjz23isnfbh5bcl4jbmahp6r4 41 24 short- short- NNS work_lbjz23isnfbh5bcl4jbmahp6r4 41 25 as as RB work_lbjz23isnfbh5bcl4jbmahp6r4 41 26 well well RB work_lbjz23isnfbh5bcl4jbmahp6r4 41 27 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 41 28 long long JJ work_lbjz23isnfbh5bcl4jbmahp6r4 41 29 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 41 30 term term NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 31 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 41 32 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 41 33 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 41 34 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 35 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 41 36 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 41 37 67 67 CD work_lbjz23isnfbh5bcl4jbmahp6r4 41 38 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 41 39 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 42 1 A a DT work_lbjz23isnfbh5bcl4jbmahp6r4 42 2 detailed detailed JJ work_lbjz23isnfbh5bcl4jbmahp6r4 42 3 description description NN work_lbjz23isnfbh5bcl4jbmahp6r4 42 4 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 42 5 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 42 6 procedures procedure NNS work_lbjz23isnfbh5bcl4jbmahp6r4 42 7 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 42 8 published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 42 9 previously previously RB work_lbjz23isnfbh5bcl4jbmahp6r4 42 10 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 42 11 31 31 CD work_lbjz23isnfbh5bcl4jbmahp6r4 42 12 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 42 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 43 1 Main main JJ work_lbjz23isnfbh5bcl4jbmahp6r4 43 2 eligibility eligibility NN work_lbjz23isnfbh5bcl4jbmahp6r4 43 3 criteria criterion NNS work_lbjz23isnfbh5bcl4jbmahp6r4 43 4 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 43 5 similar similar JJ work_lbjz23isnfbh5bcl4jbmahp6r4 43 6 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 43 7 study study VB work_lbjz23isnfbh5bcl4jbmahp6r4 43 8 A. a. NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 1 As as IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 2 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 3 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 4 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 44 5 primarily primarily RB work_lbjz23isnfbh5bcl4jbmahp6r4 44 6 designed design VBN work_lbjz23isnfbh5bcl4jbmahp6r4 44 7 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 44 8 investigate investigate VB work_lbjz23isnfbh5bcl4jbmahp6r4 44 9 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 44 10 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 11 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 12 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 44 13 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 14 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 15 testosterone testosterone NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 16 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 44 17 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 18 obese obese JJ work_lbjz23isnfbh5bcl4jbmahp6r4 44 19 men man NNS work_lbjz23isnfbh5bcl4jbmahp6r4 44 20 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 21 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 44 22 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 44 23 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 24 testosterone testosterone NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 44 26 all all DT work_lbjz23isnfbh5bcl4jbmahp6r4 44 27 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 44 28 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 44 29 male male JJ work_lbjz23isnfbh5bcl4jbmahp6r4 44 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 44 31 aged age VBN work_lbjz23isnfbh5bcl4jbmahp6r4 44 32 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 44 33 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 44 34 75 75 CD work_lbjz23isnfbh5bcl4jbmahp6r4 44 35 years year NNS work_lbjz23isnfbh5bcl4jbmahp6r4 44 36 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 44 37 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 44 38 BMI bmi NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 39 > > NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 40 30 30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 44 41 kg kg NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 42 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 44 43 m2 m2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 44 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 44 45 total total JJ work_lbjz23isnfbh5bcl4jbmahp6r4 44 46 testosterone testosterone NN work_lbjz23isnfbh5bcl4jbmahp6r4 44 47 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 44 48 < < XX work_lbjz23isnfbh5bcl4jbmahp6r4 44 49 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 44 50 nmol nmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 44 51 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 44 52 L. L. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 1 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 45 2 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 45 3 randomized randomized JJ work_lbjz23isnfbh5bcl4jbmahp6r4 45 4 1:1 1:1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 5 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 45 6 receive receive VB work_lbjz23isnfbh5bcl4jbmahp6r4 45 7 either either CC work_lbjz23isnfbh5bcl4jbmahp6r4 45 8 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 9 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 45 10 Kineret Kineret NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 11 ® ® NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 12 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 13 mg mg NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 14 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 45 15 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 16 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 17 s.c s.c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 18 . . NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 19 injection injection VBP work_lbjz23isnfbh5bcl4jbmahp6r4 45 20 twice twice RB work_lbjz23isnfbh5bcl4jbmahp6r4 45 21 daily daily RB work_lbjz23isnfbh5bcl4jbmahp6r4 45 22 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 23 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 45 24 time time NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 25 interval interval NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 26 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 27 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 28 h. h. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 29 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 30 visits visit NNS work_lbjz23isnfbh5bcl4jbmahp6r4 45 31 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 45 32 scheduled schedule VBN work_lbjz23isnfbh5bcl4jbmahp6r4 45 33 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 34 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 45 35 morning morning NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 36 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 37 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 45 38 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 45 39 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 40 0 0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 41 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 45 42 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 45 43 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 44 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 45 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 46 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 45 47 short short JJ work_lbjz23isnfbh5bcl4jbmahp6r4 45 48 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 45 49 term term NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 50 visit visit NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 51 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 45 52 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 45 53 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 54 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 45 55 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 56 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 45 57 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 45 58 4 4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 45 59 weeks week NNS work_lbjz23isnfbh5bcl4jbmahp6r4 45 60 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 46 1 Blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 46 2 samples sample NNS work_lbjz23isnfbh5bcl4jbmahp6r4 46 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 46 4 drawn draw VBN work_lbjz23isnfbh5bcl4jbmahp6r4 46 5 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 46 6 every every DT work_lbjz23isnfbh5bcl4jbmahp6r4 46 7 visit visit NN work_lbjz23isnfbh5bcl4jbmahp6r4 46 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 47 1 Therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 47 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 47 3 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 47 4 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 47 5 instructed instruct VBN work_lbjz23isnfbh5bcl4jbmahp6r4 47 6 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 47 7 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 47 8 eat eat VB work_lbjz23isnfbh5bcl4jbmahp6r4 47 9 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 47 10 drink drink VB work_lbjz23isnfbh5bcl4jbmahp6r4 47 11 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 47 12 midnight midnight NN work_lbjz23isnfbh5bcl4jbmahp6r4 47 13 before before IN work_lbjz23isnfbh5bcl4jbmahp6r4 47 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 47 15 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 47 16 visits visit NNS work_lbjz23isnfbh5bcl4jbmahp6r4 47 17 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 47 18 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 47 19 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 47 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 48 1 Laboratory laboratory NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 2 analyses analyse VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 48 3 Routine routine JJ work_lbjz23isnfbh5bcl4jbmahp6r4 48 4 laboratory laboratory NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 5 parameters parameter NNS work_lbjz23isnfbh5bcl4jbmahp6r4 48 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 48 7 that that RB work_lbjz23isnfbh5bcl4jbmahp6r4 48 8 is is RB work_lbjz23isnfbh5bcl4jbmahp6r4 48 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 48 10 total total JJ work_lbjz23isnfbh5bcl4jbmahp6r4 48 11 cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 48 13 HDL hdl NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 14 cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 15 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 48 16 HbA1c hba1c UH work_lbjz23isnfbh5bcl4jbmahp6r4 48 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 48 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 48 19 triglyceride triglyceride NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 20 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 48 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 48 22 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 48 23 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 24 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 48 25 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 48 26 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 48 27 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 48 28 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 29 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 30 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 31 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 48 32 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 33 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 48 34 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 35 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 36 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 48 37 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 38 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 48 39 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 48 40 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 48 41 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 48 42 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 48 43 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 44 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 45 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 48 46 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 48 47 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 48 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 48 49 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 48 50 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 51 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 48 52 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 48 53 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 48 54 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 55 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 56 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 57 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 58 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 59 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 60 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 61   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 48 62 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 48 63 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 49 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 49 2 role role NN 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. work_lbjz23isnfbh5bcl4jbmahp6r4 50 1 At at IN work_lbjz23isnfbh5bcl4jbmahp6r4 50 2 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 50 3 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 50 4 Hospital Hospital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 50 5 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 50 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 50 7 all all DT work_lbjz23isnfbh5bcl4jbmahp6r4 50 8 routine routine JJ work_lbjz23isnfbh5bcl4jbmahp6r4 50 9 parameters parameter NNS work_lbjz23isnfbh5bcl4jbmahp6r4 50 10 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 50 11 measured measure VBN work_lbjz23isnfbh5bcl4jbmahp6r4 50 12 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 50 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 50 14 Cobas Cobas NNP work_lbjz23isnfbh5bcl4jbmahp6r4 50 15 8000 8000 CD work_lbjz23isnfbh5bcl4jbmahp6r4 50 16 c502 c502 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 50 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 50 18 Roche Roche NNP work_lbjz23isnfbh5bcl4jbmahp6r4 50 19 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 50 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 51 1 At at IN work_lbjz23isnfbh5bcl4jbmahp6r4 51 2 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 51 3 Kantonsspital Kantonsspital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 4 Aarau Aarau NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 51 6 total total NN work_lbjz23isnfbh5bcl4jbmahp6r4 51 7 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 51 8 HDL hdl NN work_lbjz23isnfbh5bcl4jbmahp6r4 51 9 cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 51 10 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 51 11 measured measure VBN work_lbjz23isnfbh5bcl4jbmahp6r4 51 12 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 51 13 immunoassay immunoassay NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 14 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 51 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 51 16 Architect Architect NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 17 i2000SR i2000sr NN work_lbjz23isnfbh5bcl4jbmahp6r4 51 18 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 51 19 Abbott Abbott NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 20 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 51 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 51 22 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 51 23 HbA1c HbA1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 24 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 51 25 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 51 26 performed perform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 51 27 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 51 28 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 51 29 D-100 D-100 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 30 testing testing NN work_lbjz23isnfbh5bcl4jbmahp6r4 51 31 systems system NNS work_lbjz23isnfbh5bcl4jbmahp6r4 51 32 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 51 33 BIORAD BIORAD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 51 34 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 52 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 52 2 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 52 3 centers center NNS work_lbjz23isnfbh5bcl4jbmahp6r4 52 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 52 5 LDL LDL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 52 6 cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 52 7 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 52 8 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 52 9 calculated calculate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 52 10 using use VBG work_lbjz23isnfbh5bcl4jbmahp6r4 52 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 52 12 Friedewald Friedewald NNP work_lbjz23isnfbh5bcl4jbmahp6r4 52 13 formula formula NN work_lbjz23isnfbh5bcl4jbmahp6r4 52 14 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 52 15 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 52 16 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 52 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 53 1 CRP CRP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 53 2 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 53 3 determined determine VBN work_lbjz23isnfbh5bcl4jbmahp6r4 53 4 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 53 5 an an DT 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Gen. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 53 17 3 3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 53 18 Test Test NNP work_lbjz23isnfbh5bcl4jbmahp6r4 53 19 ; ; : work_lbjz23isnfbh5bcl4jbmahp6r4 53 20 Roche Roche NNP work_lbjz23isnfbh5bcl4jbmahp6r4 53 21 Diagnostics Diagnostics NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 53 22 GmbH GmbH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 53 23 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 53 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 54 1 Plasma Plasma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 2 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 54 3 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 54 4 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 54 5 measured measure VBN work_lbjz23isnfbh5bcl4jbmahp6r4 54 6 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 54 7 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 54 8 commercial commercial JJ work_lbjz23isnfbh5bcl4jbmahp6r4 54 9 automated automate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 54 10 immunofluorescence immunofluorescence NN work_lbjz23isnfbh5bcl4jbmahp6r4 54 11 assay assay NN work_lbjz23isnfbh5bcl4jbmahp6r4 54 12 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 54 13 B.R.A.H.M.S B.R.A.H.M.S : work_lbjz23isnfbh5bcl4jbmahp6r4 54 14 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 15 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 54 16 proAVP proAVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 17 KRYPTOR KRYPTOR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 54 19 BRAHMS BRAHMS NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 20 GmbH GmbH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 54 22 part part NN work_lbjz23isnfbh5bcl4jbmahp6r4 54 23 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 54 24 Thermo Thermo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 25 Fisher Fisher NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 26 Scientific Scientific NNP work_lbjz23isnfbh5bcl4jbmahp6r4 54 27 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 54 28 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 54 29 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 54 30 batch batch NN work_lbjz23isnfbh5bcl4jbmahp6r4 54 31 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 54 32 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 55 1 For for IN work_lbjz23isnfbh5bcl4jbmahp6r4 55 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 55 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 55 4 EDTA EDTA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 55 5 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 55 6 samples sample NNS work_lbjz23isnfbh5bcl4jbmahp6r4 55 7 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 55 8 centrifuged centrifuge VBN work_lbjz23isnfbh5bcl4jbmahp6r4 55 9 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 55 10 4 4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 55 11 ° ° NNS work_lbjz23isnfbh5bcl4jbmahp6r4 55 12 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 55 13 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 55 14 stored store VBN work_lbjz23isnfbh5bcl4jbmahp6r4 55 15 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 55 16 −76 −76 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 55 17 ° ° , work_lbjz23isnfbh5bcl4jbmahp6r4 55 18 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 55 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 56 1 Statistical statistical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 56 2 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 56 3 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 56 4 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 56 5 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 56 6 log log NN work_lbjz23isnfbh5bcl4jbmahp6r4 56 7 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 56 8 transformed transform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 56 9 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 56 10 order order NN work_lbjz23isnfbh5bcl4jbmahp6r4 56 11 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 56 12 achieve achieve VB work_lbjz23isnfbh5bcl4jbmahp6r4 56 13 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 56 14 distribution distribution NN work_lbjz23isnfbh5bcl4jbmahp6r4 56 15 analog analog NN work_lbjz23isnfbh5bcl4jbmahp6r4 56 16 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 56 17 normal normal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 56 18 distribution distribution NN work_lbjz23isnfbh5bcl4jbmahp6r4 56 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 57 1 Thereby thereby RB work_lbjz23isnfbh5bcl4jbmahp6r4 57 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 57 3 one one CD work_lbjz23isnfbh5bcl4jbmahp6r4 57 4 patient patient NN work_lbjz23isnfbh5bcl4jbmahp6r4 57 5 had have VBD work_lbjz23isnfbh5bcl4jbmahp6r4 57 6 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 57 7 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 57 8 excluded exclude VBN work_lbjz23isnfbh5bcl4jbmahp6r4 57 9 due due JJ work_lbjz23isnfbh5bcl4jbmahp6r4 57 10 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 57 11 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 57 12 extreme extreme JJ work_lbjz23isnfbh5bcl4jbmahp6r4 57 13 value value NN work_lbjz23isnfbh5bcl4jbmahp6r4 57 14 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 57 15 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 57 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 57 17 129 129 CD work_lbjz23isnfbh5bcl4jbmahp6r4 57 18 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 57 19 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 57 20 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 57 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 57 22 resulting result VBG work_lbjz23isnfbh5bcl4jbmahp6r4 57 23 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 57 24 n n NN work_lbjz23isnfbh5bcl4jbmahp6r4 57 25 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 57 26 66 66 CD work_lbjz23isnfbh5bcl4jbmahp6r4 57 27 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 57 28 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 57 29 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 57 30 B. B. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 58 1 Unless unless IN work_lbjz23isnfbh5bcl4jbmahp6r4 58 2 stated state VBN work_lbjz23isnfbh5bcl4jbmahp6r4 58 3 otherwise otherwise RB work_lbjz23isnfbh5bcl4jbmahp6r4 58 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 58 5 categorical categorical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 58 6 variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 58 7 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 58 8 expressed express VBN work_lbjz23isnfbh5bcl4jbmahp6r4 58 9 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 58 10 count count NN work_lbjz23isnfbh5bcl4jbmahp6r4 58 11 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 58 12 percentage percentage NN work_lbjz23isnfbh5bcl4jbmahp6r4 58 13 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 58 14 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 58 15 continuous continuous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 58 16 variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 58 17 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 58 18 means mean NNS work_lbjz23isnfbh5bcl4jbmahp6r4 58 19 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 58 20 ±s.d ±s.d NNP work_lbjz23isnfbh5bcl4jbmahp6r4 58 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 58 22 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 58 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 59 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 59 2 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 59 3 first first JJ work_lbjz23isnfbh5bcl4jbmahp6r4 59 4 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 59 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 59 6 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 59 7 aimed aim VBD work_lbjz23isnfbh5bcl4jbmahp6r4 59 8 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 59 9 investigate investigate VB work_lbjz23isnfbh5bcl4jbmahp6r4 59 10 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 59 11 parameters parameter NNS work_lbjz23isnfbh5bcl4jbmahp6r4 59 12 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 59 13 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 59 14 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 59 15 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 59 16 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 59 17 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 59 18 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 59 19 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 59 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 60 1 Therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 60 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 60 3 linear linear JJ work_lbjz23isnfbh5bcl4jbmahp6r4 60 4 regression regression NN work_lbjz23isnfbh5bcl4jbmahp6r4 60 5 models model NNS work_lbjz23isnfbh5bcl4jbmahp6r4 60 6 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 60 7 calculated calculate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 60 8 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 60 9 log log NN work_lbjz23isnfbh5bcl4jbmahp6r4 60 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 60 11 transformed transform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 60 12 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 60 13 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 60 14 dependent dependent JJ work_lbjz23isnfbh5bcl4jbmahp6r4 60 15 variable variable NN work_lbjz23isnfbh5bcl4jbmahp6r4 60 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 60 17 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 60 18 respective respective JJ work_lbjz23isnfbh5bcl4jbmahp6r4 60 19 parameter parameter NN work_lbjz23isnfbh5bcl4jbmahp6r4 60 20 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 60 21 explanatory explanatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 60 22 variable variable NN work_lbjz23isnfbh5bcl4jbmahp6r4 60 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 61 1 All all DT work_lbjz23isnfbh5bcl4jbmahp6r4 61 2 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 61 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 61 4 adjusted adjust VBN work_lbjz23isnfbh5bcl4jbmahp6r4 61 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 61 6 sex sex NN work_lbjz23isnfbh5bcl4jbmahp6r4 61 7 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 62 1 Afterwards afterwards RB work_lbjz23isnfbh5bcl4jbmahp6r4 62 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 62 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 62 4 statistically statistically RB work_lbjz23isnfbh5bcl4jbmahp6r4 62 5 significant significant JJ work_lbjz23isnfbh5bcl4jbmahp6r4 62 6 variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 62 7 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 62 8 selected select VBN work_lbjz23isnfbh5bcl4jbmahp6r4 62 9 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 62 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 62 11 combined combined JJ work_lbjz23isnfbh5bcl4jbmahp6r4 62 12 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 62 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 63 1 These these DT work_lbjz23isnfbh5bcl4jbmahp6r4 63 2 variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 63 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 63 4 combined combine VBN work_lbjz23isnfbh5bcl4jbmahp6r4 63 5 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 63 6 = = NNS work_lbjz23isnfbh5bcl4jbmahp6r4 63 7 added add VBN work_lbjz23isnfbh5bcl4jbmahp6r4 63 8 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 63 9 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 63 10 explanatory explanatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 63 11 variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 63 12 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 63 13 one one CD work_lbjz23isnfbh5bcl4jbmahp6r4 63 14 linear linear JJ work_lbjz23isnfbh5bcl4jbmahp6r4 63 15 regression regression NN work_lbjz23isnfbh5bcl4jbmahp6r4 63 16 model model NN work_lbjz23isnfbh5bcl4jbmahp6r4 63 17 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 63 18 investigate investigate VB work_lbjz23isnfbh5bcl4jbmahp6r4 63 19 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 63 20 factors factor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 63 21 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 63 22 independently independently RB work_lbjz23isnfbh5bcl4jbmahp6r4 63 23 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 63 24 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 63 25 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 63 26 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 63 27 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 64 1 To to TO work_lbjz23isnfbh5bcl4jbmahp6r4 64 2 assess assess VB work_lbjz23isnfbh5bcl4jbmahp6r4 64 3 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 4 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 64 5 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 64 6 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 7 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 64 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 64 9 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 64 10 used use VBD work_lbjz23isnfbh5bcl4jbmahp6r4 64 11 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 64 12 linear linear JJ work_lbjz23isnfbh5bcl4jbmahp6r4 64 13 mixed mixed JJ work_lbjz23isnfbh5bcl4jbmahp6r4 64 14 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 64 15 model model NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 16 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 64 17 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 18 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 19 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 64 20 baseline baseline VB work_lbjz23isnfbh5bcl4jbmahp6r4 64 21 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 22 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 64 23 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 64 24 fixed fix VBN work_lbjz23isnfbh5bcl4jbmahp6r4 64 25 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 26 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 64 27 participant participant NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 28 ID ID NNP work_lbjz23isnfbh5bcl4jbmahp6r4 64 29 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 64 30 random random JJ work_lbjz23isnfbh5bcl4jbmahp6r4 64 31 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 64 32 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 65 1 To to TO work_lbjz23isnfbh5bcl4jbmahp6r4 65 2 investigate investigate VB work_lbjz23isnfbh5bcl4jbmahp6r4 65 3 whether whether IN work_lbjz23isnfbh5bcl4jbmahp6r4 65 4 defined defined JJ work_lbjz23isnfbh5bcl4jbmahp6r4 65 5 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 65 6 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 65 7 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 65 8 responded respond VBD work_lbjz23isnfbh5bcl4jbmahp6r4 65 9 differently differently RB work_lbjz23isnfbh5bcl4jbmahp6r4 65 10 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 65 11 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 65 12 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 65 13 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 65 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 65 15 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 65 16 conducted conduct VBD work_lbjz23isnfbh5bcl4jbmahp6r4 65 17 subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 65 18 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 65 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 66 1 For for IN work_lbjz23isnfbh5bcl4jbmahp6r4 66 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 66 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 66 4 linear linear JJ work_lbjz23isnfbh5bcl4jbmahp6r4 66 5 regression regression NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 6 models model NNS work_lbjz23isnfbh5bcl4jbmahp6r4 66 7 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 66 8 calculated calculate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 66 9 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 66 10 log- log- DT work_lbjz23isnfbh5bcl4jbmahp6r4 66 11 transformed transform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 66 12 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 66 13 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 66 14 dependent dependent JJ work_lbjz23isnfbh5bcl4jbmahp6r4 66 15 variable variable NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 66 17 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 66 18 following follow VBG work_lbjz23isnfbh5bcl4jbmahp6r4 66 19 interaction interaction NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 20 term term NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 21 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 66 22 explanatory explanatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 66 23 variable variable NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 24 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 66 25 Treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 26 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 27 * * NFP work_lbjz23isnfbh5bcl4jbmahp6r4 66 28 subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 29 variable variable NN work_lbjz23isnfbh5bcl4jbmahp6r4 66 30 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 67 1 These these DT work_lbjz23isnfbh5bcl4jbmahp6r4 67 2 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 67 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 67 4 adjusted adjust VBN work_lbjz23isnfbh5bcl4jbmahp6r4 67 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 67 6 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 67 7 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 67 8 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 67 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 67 10 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 67 11 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 67 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 67 13 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 67 14 sex sex NN work_lbjz23isnfbh5bcl4jbmahp6r4 67 15 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 68 1 All all DT work_lbjz23isnfbh5bcl4jbmahp6r4 68 2 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 68 3 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 68 4 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 68 5 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 68 6 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 68 7 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 68 8 sided sided JJ work_lbjz23isnfbh5bcl4jbmahp6r4 68 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 68 10 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 68 11 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 68 12 been be VBN work_lbjz23isnfbh5bcl4jbmahp6r4 68 13 adjusted adjust VBN work_lbjz23isnfbh5bcl4jbmahp6r4 68 14 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 68 15 multiple multiple JJ work_lbjz23isnfbh5bcl4jbmahp6r4 68 16 testing testing NN work_lbjz23isnfbh5bcl4jbmahp6r4 68 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 69 1 Statistical statistical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 69 2 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 69 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 69 4 performed perform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 69 5 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 69 6 graphs graphs JJ work_lbjz23isnfbh5bcl4jbmahp6r4 69 7 drawn drawn NN work_lbjz23isnfbh5bcl4jbmahp6r4 69 8 using use VBG work_lbjz23isnfbh5bcl4jbmahp6r4 69 9 R R NNP work_lbjz23isnfbh5bcl4jbmahp6r4 69 10 i386 i386 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 69 11 Version Version NNP work_lbjz23isnfbh5bcl4jbmahp6r4 69 12 3.4.1 3.4.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 69 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 70 1 Results Results NNP work_lbjz23isnfbh5bcl4jbmahp6r4 70 2 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 70 3 characteristics characteristic NNS work_lbjz23isnfbh5bcl4jbmahp6r4 70 4 Baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 70 5 characteristics characteristic NNS work_lbjz23isnfbh5bcl4jbmahp6r4 70 6 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 70 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 70 8 73 73 CD work_lbjz23isnfbh5bcl4jbmahp6r4 70 9 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 70 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 70 11 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 70 12 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 70 13 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 70 14 66 66 CD work_lbjz23isnfbh5bcl4jbmahp6r4 70 15 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 70 16 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 70 17 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 70 18 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 70 19 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 70 20 shown show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 70 21 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 70 22 Table table NN work_lbjz23isnfbh5bcl4jbmahp6r4 70 23 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 70 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 71 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 71 2 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 71 3 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 71 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 71 5 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 71 6 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 71 7 characteristics characteristic NNS work_lbjz23isnfbh5bcl4jbmahp6r4 71 8 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 71 9 well well RB work_lbjz23isnfbh5bcl4jbmahp6r4 71 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 71 11 balanced balance VBN work_lbjz23isnfbh5bcl4jbmahp6r4 71 12 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 71 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 71 14 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 71 15 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 71 16 groups group NNS work_lbjz23isnfbh5bcl4jbmahp6r4 71 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 72 1 To to TO work_lbjz23isnfbh5bcl4jbmahp6r4 72 2 summarize summarize VB work_lbjz23isnfbh5bcl4jbmahp6r4 72 3 briefly briefly RB work_lbjz23isnfbh5bcl4jbmahp6r4 72 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 72 5 49.3 49.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 72 6 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 72 7 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 72 8 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 72 9 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 72 10 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 72 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 72 12 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 72 13 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 72 14 male male JJ work_lbjz23isnfbh5bcl4jbmahp6r4 72 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 72 16 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 72 17 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 72 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 72 19 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 72 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 72 21 respectively respectively RB work_lbjz23isnfbh5bcl4jbmahp6r4 72 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 73 1 Mean mean JJ work_lbjz23isnfbh5bcl4jbmahp6r4 73 2 age age NN work_lbjz23isnfbh5bcl4jbmahp6r4 73 3 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 73 4 54 54 CD work_lbjz23isnfbh5bcl4jbmahp6r4 73 5 years year NNS work_lbjz23isnfbh5bcl4jbmahp6r4 73 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 74 1 Mean Mean NNP work_lbjz23isnfbh5bcl4jbmahp6r4 74 2 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 74 3 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 74 4 approximately approximately RB work_lbjz23isnfbh5bcl4jbmahp6r4 74 5 37 37 CD work_lbjz23isnfbh5bcl4jbmahp6r4 74 6 kg kg NN work_lbjz23isnfbh5bcl4jbmahp6r4 74 7 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 74 8 m2 m2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 74 9 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 74 10 nearly nearly RB work_lbjz23isnfbh5bcl4jbmahp6r4 74 11 all all DT work_lbjz23isnfbh5bcl4jbmahp6r4 74 12 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 74 13 having have VBG work_lbjz23isnfbh5bcl4jbmahp6r4 74 14 visceral visceral JJ work_lbjz23isnfbh5bcl4jbmahp6r4 74 15 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 74 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 75 1 Around around IN work_lbjz23isnfbh5bcl4jbmahp6r4 75 2 70 70 CD work_lbjz23isnfbh5bcl4jbmahp6r4 75 3 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 75 4 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 75 5 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 75 6 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 75 7 presented present VBN work_lbjz23isnfbh5bcl4jbmahp6r4 75 8 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 75 9 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 75 10 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 75 11 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 75 12 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 75 13 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 75 14 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 75 15 defined define VBN work_lbjz23isnfbh5bcl4jbmahp6r4 75 16 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 75 17 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 75 18 CRP crp NN work_lbjz23isnfbh5bcl4jbmahp6r4 75 19 level level NN work_lbjz23isnfbh5bcl4jbmahp6r4 75 20 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 75 21 ≥2 ≥2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 75 22 mg mg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 75 23 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 75 24 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 75 25 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 75 26 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 76 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 76 2 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 76 3 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 76 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 76 5 86.3 86.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 76 6 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 76 7 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 76 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 76 9 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 76 10 suffered suffer VBD work_lbjz23isnfbh5bcl4jbmahp6r4 76 11 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 76 12 either either DT work_lbjz23isnfbh5bcl4jbmahp6r4 76 13 prediabetes prediabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 76 14 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 76 15 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 76 16 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 76 17 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 76 18 compared compare VBN work_lbjz23isnfbh5bcl4jbmahp6r4 76 19 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 76 20 51.5 51.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 76 21 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 76 22 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 76 23 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 76 24 B. B. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 77 1 Furthermore furthermore RB work_lbjz23isnfbh5bcl4jbmahp6r4 77 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 77 3 72 72 CD work_lbjz23isnfbh5bcl4jbmahp6r4 77 4 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 5 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 77 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 77 7 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 77 8 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 77 9 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 10 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 77 11 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 77 12 treated treat VBN work_lbjz23isnfbh5bcl4jbmahp6r4 77 13 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 77 14 antihypertensive antihypertensive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 77 15 medication medication NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 77 17 whereas whereas IN work_lbjz23isnfbh5bcl4jbmahp6r4 77 18 45 45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 77 19 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 20 had have VBD work_lbjz23isnfbh5bcl4jbmahp6r4 77 21 antihypertensive antihypertensive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 77 22 drugs drug NNS work_lbjz23isnfbh5bcl4jbmahp6r4 77 23 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 77 24 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 25 B. B. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 77 26 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 77 27 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 28 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 77 29 Figure figure NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 30 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 77 31 shows show VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 77 32 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 77 33 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 77 34 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 77 35 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 77 36 different different JJ work_lbjz23isnfbh5bcl4jbmahp6r4 77 37 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 77 38 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 78 1 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 78 2 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 78 3 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 78 4 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 78 5 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 78 6 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 78 7 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 78 8 had have VBD work_lbjz23isnfbh5bcl4jbmahp6r4 78 9 significantly significantly RB work_lbjz23isnfbh5bcl4jbmahp6r4 78 10 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 78 11 median median JJ work_lbjz23isnfbh5bcl4jbmahp6r4 78 12 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 78 13 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 78 14 than than IN work_lbjz23isnfbh5bcl4jbmahp6r4 78 15 those those DT work_lbjz23isnfbh5bcl4jbmahp6r4 78 16 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 78 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 78 18 7.7 7.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 78 19 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 78 20 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 78 21 4.9–11.9 4.9–11.9 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 78 22 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 78 23 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 78 24 5.8 5.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 78 25 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 78 26 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 78 27 3.9–9.3 3.9–9.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 78 28 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 78 29 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 78 30 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 78 31 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 78 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 78 33 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 78 34 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 78 35 0.009 0.009 CD work_lbjz23isnfbh5bcl4jbmahp6r4 78 36 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 78 37 Fig Fig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 78 38 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 79 1 1a 1a LS work_lbjz23isnfbh5bcl4jbmahp6r4 79 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 79 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 80 1 We -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 80 2 observed observe VBD work_lbjz23isnfbh5bcl4jbmahp6r4 80 3 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 80 4 increase increase NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 6 median median JJ work_lbjz23isnfbh5bcl4jbmahp6r4 80 7 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 80 8 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 80 9 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 10 dependence dependence NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 11 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 12 diabetic diabetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 80 13 status status NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 80 15 that that RB work_lbjz23isnfbh5bcl4jbmahp6r4 80 16 is is RB work_lbjz23isnfbh5bcl4jbmahp6r4 80 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 80 18 median median JJ work_lbjz23isnfbh5bcl4jbmahp6r4 80 19 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 20 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 80 21 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 22 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 80 23 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 24 diabetes diabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 80 25 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 80 26 6.0 6.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 27 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 28 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 80 29 4.7–8.0 4.7–8.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 30 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 31 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 32 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 80 33 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 80 35 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 36 those those DT work_lbjz23isnfbh5bcl4jbmahp6r4 80 37 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 38 prediabetes prediabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 80 39 7.3 7.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 40 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 41 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 80 42 4.9–11.0 4.9–11.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 43 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 44 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 45 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 80 46 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 47 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 80 48 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 80 49 8.5 8.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 50 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 51 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 80 52 4.0–14.1 4.0–14.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 53 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 54 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 55 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 80 56 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 57 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 58 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 80 59 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 80 60 overt overt JJ work_lbjz23isnfbh5bcl4jbmahp6r4 80 61 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 62 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 63 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 64 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 80 65 overall overall JJ work_lbjz23isnfbh5bcl4jbmahp6r4 80 66 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 80 67 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 80 68 0.03 0.03 CD work_lbjz23isnfbh5bcl4jbmahp6r4 80 69 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 80 70 Fig Fig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 80 71 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 81 1 1b 1b NN work_lbjz23isnfbh5bcl4jbmahp6r4 81 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 81 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 82 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 82 2 same same JJ work_lbjz23isnfbh5bcl4jbmahp6r4 82 3 held hold VBN work_lbjz23isnfbh5bcl4jbmahp6r4 82 4 true true JJ work_lbjz23isnfbh5bcl4jbmahp6r4 82 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 82 6 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 82 7 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 82 8 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 82 9 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 82 10 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 11 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 82 12 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 13 antihypertensive antihypertensive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 82 14 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 82 15 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 16 7.7 7.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 82 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 18 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 82 19 4.8–13.1 4.8–13.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 82 20 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 21 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 82 22 6.4 6.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 82 23 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 24 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 82 25 4.2–9.1 4.2–9.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 82 26 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 82 27 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 82 28 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 82 29 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 82 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 82 31 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 82 32 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 82 33 0.013 0.013 CD work_lbjz23isnfbh5bcl4jbmahp6r4 82 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 82 35 Fig fig NN work_lbjz23isnfbh5bcl4jbmahp6r4 82 36 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 83 1 1c 1c LS work_lbjz23isnfbh5bcl4jbmahp6r4 83 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 83 4 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 5 2 2 LS work_lbjz23isnfbh5bcl4jbmahp6r4 83 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 7 lipid lipid NN work_lbjz23isnfbh5bcl4jbmahp6r4 83 8 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 83 9 lowering lower VBG work_lbjz23isnfbh5bcl4jbmahp6r4 83 10 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 83 11 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 12 8.8 8.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 83 13 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 14 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 83 15 4.5–11.6 4.5–11.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 83 16 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 17 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 83 18 6.6 6.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 83 19 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 20 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 83 21 4.3–9.5 4.3–9.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 83 22 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 83 23 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 83 24 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 83 25 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 83 26 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 83 27 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 83 28 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 83 29 0.009 0.009 CD work_lbjz23isnfbh5bcl4jbmahp6r4 83 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 83 31 Fig Fig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 83 32 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 84 1 1d 1d NNP work_lbjz23isnfbh5bcl4jbmahp6r4 84 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 84 4 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 84 5 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 6 3 3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 84 7 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 8 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 84 9 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 84 10 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 84 11 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 84 12 above above IN work_lbjz23isnfbh5bcl4jbmahp6r4 84 13 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 84 14 below below IN work_lbjz23isnfbh5bcl4jbmahp6r4 84 15 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 84 16 kg kg NNS work_lbjz23isnfbh5bcl4jbmahp6r4 84 17 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 84 18 m2 m2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 84 19 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 20 7.8 7.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 84 21 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 22 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 84 23 5.4–11.7 5.4–11.7 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 84 24 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 25 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 84 26 4.9 4.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 84 27 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 28 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 84 29 3.7–9.8 3.7–9.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 84 30 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 84 31 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 84 32 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 84 33 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 84 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 84 35 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 84 36 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 84 37 0.008 0.008 CD work_lbjz23isnfbh5bcl4jbmahp6r4 84 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 84 39 Fig Fig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 84 40 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 85 1 1e 1e LS work_lbjz23isnfbh5bcl4jbmahp6r4 85 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 85 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 86 1 When when WRB work_lbjz23isnfbh5bcl4jbmahp6r4 86 2 adding add VBG work_lbjz23isnfbh5bcl4jbmahp6r4 86 3 all all PDT work_lbjz23isnfbh5bcl4jbmahp6r4 86 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 86 5 investigated investigated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 86 6 parameters parameter NNS work_lbjz23isnfbh5bcl4jbmahp6r4 86 7 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 86 8 i.e. i.e. FW work_lbjz23isnfbh5bcl4jbmahp6r4 87 1 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 2 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 3 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 87 4 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 5 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 87 7 diabetic diabetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 8 status status NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 87 10 antihypertensive antihypertensive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 87 12 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 87 13 lipid lipid NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 87 15 lowering lower VBG work_lbjz23isnfbh5bcl4jbmahp6r4 87 16 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 87 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 87 19 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 87 20 categories category NNS work_lbjz23isnfbh5bcl4jbmahp6r4 87 21 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 87 22 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 87 23 one one CD work_lbjz23isnfbh5bcl4jbmahp6r4 87 24 model model NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 87 26 only only RB work_lbjz23isnfbh5bcl4jbmahp6r4 87 27 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 28 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 29 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 87 30 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 31 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 32 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 87 33 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 87 34 remained remain VBD work_lbjz23isnfbh5bcl4jbmahp6r4 87 35 significantly significantly RB work_lbjz23isnfbh5bcl4jbmahp6r4 87 36 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 87 37 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 87 38 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 87 39 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 87 40 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 87 41 PInflamm PInflamm NNP work_lbjz23isnfbh5bcl4jbmahp6r4 87 42 < < XX work_lbjz23isnfbh5bcl4jbmahp6r4 87 43 0.01 0.01 XX work_lbjz23isnfbh5bcl4jbmahp6r4 87 44 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 87 45 PBMI PBMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 87 46 = = NFP work_lbjz23isnfbh5bcl4jbmahp6r4 87 47 0.02 0.02 CD work_lbjz23isnfbh5bcl4jbmahp6r4 87 48 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 87 49 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 88 1 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 88 2 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 88 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 88 4 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 88 5 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 88 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 88 7 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 8 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 9 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 88 11 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 12 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 88 13 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 14 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 15 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 88 16 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 17 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 88 18 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 88 19 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 88 20 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 88 21 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 88 22 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 23 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 24 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 88 25 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 88 26 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 27 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 88 28 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 88 29 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 88 30 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 88 31 free free JJ 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work_lbjz23isnfbh5bcl4jbmahp6r4 89 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 89 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 9 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 10 718 718 CD work_lbjz23isnfbh5bcl4jbmahp6r4 89 11 PB PB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 12 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 89 13 XX XX NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 14 9:7 9:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 89 15 Effect Effect NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 17 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 18 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 19 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 20 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 21 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 22 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 89 23 Median median JJ work_lbjz23isnfbh5bcl4jbmahp6r4 89 24 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 25 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 89 26 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 27 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 28 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 89 29 7.0 7.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 89 30 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 89 31 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 32 4.2–11.2 4.2–11.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 89 33 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 89 34 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 35 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 89 36 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 37 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 38 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 89 39 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 40 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 41 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 89 42 7.2 7.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 89 43 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 89 44 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 89 45 5.4–10.1 5.4–10.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 89 46 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 89 47 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 48 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 89 49 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 50 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 89 51 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 89 52 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 53 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 89 54 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 90 1 After after IN work_lbjz23isnfbh5bcl4jbmahp6r4 90 2 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 3 initiation initiation NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 90 5 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 6 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 90 7 did do VBD work_lbjz23isnfbh5bcl4jbmahp6r4 90 8 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 90 9 change change VB work_lbjz23isnfbh5bcl4jbmahp6r4 90 10 either either CC work_lbjz23isnfbh5bcl4jbmahp6r4 90 11 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 90 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 90 13 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 90 14 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 90 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 90 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 90 17 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 18 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 19 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 90 20 remained remain VBD work_lbjz23isnfbh5bcl4jbmahp6r4 90 21 stable stable JJ work_lbjz23isnfbh5bcl4jbmahp6r4 90 22 throughout throughout IN work_lbjz23isnfbh5bcl4jbmahp6r4 90 23 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 90 24 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 25 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 90 26 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 27 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 90 28 0.44 0.44 CD work_lbjz23isnfbh5bcl4jbmahp6r4 90 29 ; ; : work_lbjz23isnfbh5bcl4jbmahp6r4 90 30 Table table NN work_lbjz23isnfbh5bcl4jbmahp6r4 90 31 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 90 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 90 33 Fig Fig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 90 34 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 91 1 2 2 LS work_lbjz23isnfbh5bcl4jbmahp6r4 91 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 91 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 92 1 Subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 2 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 92 3 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 92 4 performed perform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 92 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 6 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 7 1 1 LS work_lbjz23isnfbh5bcl4jbmahp6r4 92 8 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 9 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 92 10 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 92 11 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 92 12 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 13 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 92 15 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 16 2 2 LS work_lbjz23isnfbh5bcl4jbmahp6r4 92 17 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 18 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 19 status status NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 92 21 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 22 2 2 LS work_lbjz23isnfbh5bcl4jbmahp6r4 92 23 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 24 BMI bmi VB work_lbjz23isnfbh5bcl4jbmahp6r4 92 25 below below IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 26 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 92 27 above above IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 28 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 92 29 kg kg NNS work_lbjz23isnfbh5bcl4jbmahp6r4 92 30 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 92 31 m2 m2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 92 33 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 92 34 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 35 4 4 LS work_lbjz23isnfbh5bcl4jbmahp6r4 92 36 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 92 37 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 92 38 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 39 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 92 40 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 92 41 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 42 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 92 43 stratification stratification NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 44 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 45 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 92 46 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 92 47 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 92 48 into into IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 49 tertile tertile JJ work_lbjz23isnfbh5bcl4jbmahp6r4 92 50 categories category NNS work_lbjz23isnfbh5bcl4jbmahp6r4 92 51 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 92 52 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 92 53 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 92 54 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 93 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 93 2 results result NNS work_lbjz23isnfbh5bcl4jbmahp6r4 93 3 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 93 4 depicted depict VBN work_lbjz23isnfbh5bcl4jbmahp6r4 93 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 93 6 Fig Fig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 93 7 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 94 1 3a 3a NNP work_lbjz23isnfbh5bcl4jbmahp6r4 94 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 94 3 b b NNP work_lbjz23isnfbh5bcl4jbmahp6r4 94 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 94 5 c c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 94 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 94 7 d. d. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 94 8 Treatment Treatment NNP work_lbjz23isnfbh5bcl4jbmahp6r4 94 9 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 94 10 no no DT work_lbjz23isnfbh5bcl4jbmahp6r4 94 11 significant significant JJ work_lbjz23isnfbh5bcl4jbmahp6r4 94 12 variable variable NN work_lbjz23isnfbh5bcl4jbmahp6r4 94 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 94 14 any any DT work_lbjz23isnfbh5bcl4jbmahp6r4 94 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 94 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 94 17 four four CD work_lbjz23isnfbh5bcl4jbmahp6r4 94 18 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 94 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 95 1 Only only RB work_lbjz23isnfbh5bcl4jbmahp6r4 95 2 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 95 3 interaction interaction NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 4 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 6 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 95 7 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 95 8 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 95 9 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 10 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 11 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 95 12 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 13 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 95 14 below below IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 15 0.05 0.05 CD work_lbjz23isnfbh5bcl4jbmahp6r4 95 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 95 17 suggesting suggest VBG work_lbjz23isnfbh5bcl4jbmahp6r4 95 18 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 19 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 95 20 has have VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 95 21 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 95 22 different different JJ work_lbjz23isnfbh5bcl4jbmahp6r4 95 23 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 24 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 25 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 95 26 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 27 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 95 28 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 95 29 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 95 30 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 31 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 95 32 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 33 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 95 34 compared compare VBN work_lbjz23isnfbh5bcl4jbmahp6r4 95 35 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 36 those those DT work_lbjz23isnfbh5bcl4jbmahp6r4 95 37 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 95 38 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 96 1 However however RB work_lbjz23isnfbh5bcl4jbmahp6r4 96 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 96 3 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 96 4 exploration exploration NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 5 revealed reveal VBD work_lbjz23isnfbh5bcl4jbmahp6r4 96 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 96 7 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 96 8 probability probability NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 96 10 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 96 11 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 12 I -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 96 13 error error VBP work_lbjz23isnfbh5bcl4jbmahp6r4 96 14 due due IN work_lbjz23isnfbh5bcl4jbmahp6r4 96 15 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 96 16 randomly randomly VB work_lbjz23isnfbh5bcl4jbmahp6r4 96 17 large large JJ work_lbjz23isnfbh5bcl4jbmahp6r4 96 18 differences difference NNS work_lbjz23isnfbh5bcl4jbmahp6r4 96 19 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 96 20 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 96 21 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 22 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 96 23 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 96 24 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 96 25 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 96 26 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 27 groups group NNS work_lbjz23isnfbh5bcl4jbmahp6r4 96 28 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 96 29 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 96 30 subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 31 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 96 32 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 96 33 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 96 34 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 96 35 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 36 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 96 37 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 97 1 Furthermore furthermore RB work_lbjz23isnfbh5bcl4jbmahp6r4 97 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 97 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 97 4 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 97 5 size size NN work_lbjz23isnfbh5bcl4jbmahp6r4 97 6 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 97 7 very very RB work_lbjz23isnfbh5bcl4jbmahp6r4 97 8 small small JJ work_lbjz23isnfbh5bcl4jbmahp6r4 97 9 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 97 10 −0.7 −0.7 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 97 11 pmol pmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 97 12 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 97 13 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 97 14 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 97 15 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 97 16 has have VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 97 17 no no DT work_lbjz23isnfbh5bcl4jbmahp6r4 97 18 clinical clinical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 97 19 relevance relevance NN work_lbjz23isnfbh5bcl4jbmahp6r4 97 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 98 1 Discussion discussion NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 2 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 3 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 98 4 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 5 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 98 6 present present VBP work_lbjz23isnfbh5bcl4jbmahp6r4 98 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 98 8 following follow VBG work_lbjz23isnfbh5bcl4jbmahp6r4 98 9 main main JJ work_lbjz23isnfbh5bcl4jbmahp6r4 98 10 findings finding NNS work_lbjz23isnfbh5bcl4jbmahp6r4 98 11 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 98 12 First first RB work_lbjz23isnfbh5bcl4jbmahp6r4 98 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 98 14 presence presence NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 16 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 98 17 1 1 LS work_lbjz23isnfbh5bcl4jbmahp6r4 98 18 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 98 19 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 98 20 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 98 21 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 98 22 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 23 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 98 25 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 26 shown show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 98 27 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 28 increased increase VBN work_lbjz23isnfbh5bcl4jbmahp6r4 98 29 CRP crp NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 30 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 98 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 98 32 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 98 33 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 98 34 2 2 LS work_lbjz23isnfbh5bcl4jbmahp6r4 98 35 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 98 36 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 98 37 BMI bmi NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 38 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 39 > > XX work_lbjz23isnfbh5bcl4jbmahp6r4 98 40 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 98 41 kg kg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 98 42 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 98 43 m2 m2 NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 44 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 98 45 independently independently RB work_lbjz23isnfbh5bcl4jbmahp6r4 98 46 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 98 47 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 48 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 98 49 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 50 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 98 51 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 52 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 98 53 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 98 54 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 98 55 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 98 56 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 99 1 Second second RB work_lbjz23isnfbh5bcl4jbmahp6r4 99 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 99 3 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 99 4 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 99 5 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 99 6 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 99 7 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 99 8 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 99 9 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 99 10 did do VBD work_lbjz23isnfbh5bcl4jbmahp6r4 99 11 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 99 12 lead lead VB work_lbjz23isnfbh5bcl4jbmahp6r4 99 13 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 99 14 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 99 15 reduction reduction NN work_lbjz23isnfbh5bcl4jbmahp6r4 99 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 99 17 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 99 18 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 99 19 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 99 20 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 99 21 patient patient JJ work_lbjz23isnfbh5bcl4jbmahp6r4 99 22 population population NN work_lbjz23isnfbh5bcl4jbmahp6r4 99 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 100 1 There there EX work_lbjz23isnfbh5bcl4jbmahp6r4 100 2 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 100 3 also also RB work_lbjz23isnfbh5bcl4jbmahp6r4 100 4 no no DT work_lbjz23isnfbh5bcl4jbmahp6r4 100 5 relevant relevant JJ work_lbjz23isnfbh5bcl4jbmahp6r4 100 6 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 100 7 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 100 8 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 100 9 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 100 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 100 11 any any DT work_lbjz23isnfbh5bcl4jbmahp6r4 100 12 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 100 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 100 14 analyzed analyze VBN work_lbjz23isnfbh5bcl4jbmahp6r4 100 15 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 100 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 101 1 Numerous numerous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 101 2 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 101 3 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 101 4 described describe VBN work_lbjz23isnfbh5bcl4jbmahp6r4 101 5 associations association NNS work_lbjz23isnfbh5bcl4jbmahp6r4 101 6 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 101 7 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 101 8 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 101 9 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 101 10 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 101 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 101 12 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 101 13 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 101 14 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 102 1 Most Most JJS work_lbjz23isnfbh5bcl4jbmahp6r4 102 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 102 3 them -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 102 4 found find VBD work_lbjz23isnfbh5bcl4jbmahp6r4 102 5 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 102 6 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 102 7 association association NN work_lbjz23isnfbh5bcl4jbmahp6r4 102 8 did do VBD work_lbjz23isnfbh5bcl4jbmahp6r4 102 9 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 102 10 persist persist VB work_lbjz23isnfbh5bcl4jbmahp6r4 102 11 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 102 12 adjusting adjust VBG work_lbjz23isnfbh5bcl4jbmahp6r4 102 13 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 102 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 102 15 single single JJ work_lbjz23isnfbh5bcl4jbmahp6r4 102 16 components component NNS work_lbjz23isnfbh5bcl4jbmahp6r4 102 17 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 102 18 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 102 19 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 102 20 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 102 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 103 1 However however RB work_lbjz23isnfbh5bcl4jbmahp6r4 103 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 3 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 103 4 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 103 5 several several JJ work_lbjz23isnfbh5bcl4jbmahp6r4 103 6 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 103 7 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 8 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 103 9 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 103 10 remained remain VBD work_lbjz23isnfbh5bcl4jbmahp6r4 103 11 independently independently RB work_lbjz23isnfbh5bcl4jbmahp6r4 103 12 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 103 13 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 103 14 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 103 15 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 103 16 6 6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 18 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 20 21 21 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 22 22 22 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 23 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 24 34 34 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 25 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 103 26 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 27 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 103 28 resistance resistance NN work_lbjz23isnfbh5bcl4jbmahp6r4 103 29 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 103 30 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 32 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 34 22 22 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 35 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 36 34 34 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 37 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 103 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 39 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 103 40 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 103 41 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 103 42 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 103 43 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 103 44 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 103 45 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 103 46 6 6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 47 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 48 8 8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 49 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 103 50 22 22 CD work_lbjz23isnfbh5bcl4jbmahp6r4 103 51 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 103 52 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 104 1 These these DT work_lbjz23isnfbh5bcl4jbmahp6r4 104 2 results result NNS work_lbjz23isnfbh5bcl4jbmahp6r4 104 3 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 104 4 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 104 5 accordance accordance NN work_lbjz23isnfbh5bcl4jbmahp6r4 104 6 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 104 7 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 104 8 findings finding NNS work_lbjz23isnfbh5bcl4jbmahp6r4 104 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 105 1 Table table NN work_lbjz23isnfbh5bcl4jbmahp6r4 105 2 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 105 3     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 105 4 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 105 5 characteristics characteristic NNS work_lbjz23isnfbh5bcl4jbmahp6r4 105 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 106 1 Variable Variable NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 2 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 3 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 4 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 5 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 6 Treatment Treatment NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 7 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 8 Anakinra Anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 9 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 10 n n NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 11     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 106 12 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 13     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 106 14 73 73 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 15 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 16 Anakinra Anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 18 n n CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 19     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 106 20 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 21     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 106 22 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 23 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 24 Placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 25 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 26 n n CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 27     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 106 28 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 29     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 106 30 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 31 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 32 Age age NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 33 54 54 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 34 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 35 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 36 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 37 55 55 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 38 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 39 13 13 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 40 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 41 53 53 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 42 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 43 14 14 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 44 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 45 Male male JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 46 sex sex NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 47 36 36 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 48 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 49 49 49 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 50 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 51 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 52 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 53 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 54 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 55 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 56 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 57 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 58 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 59 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 60 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 61 kg kg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 62 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 63 m2 m2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 64 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 65 37.4 37.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 66 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 67 5.5 5.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 68 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 69 36.8 36.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 70 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 71 4.1 4.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 72 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 73 36.6 36.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 74 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 75 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 76 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 77 Visceral visceral JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 78 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 79 72 72 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 80 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 81 99 99 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 82 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 83 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 84 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 85 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 86 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 87 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 88 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 89 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 90 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 91 Alcohol alcohol NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 92 consumption consumption NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 93 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 94 glasses glass NNS work_lbjz23isnfbh5bcl4jbmahp6r4 106 95 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 96 week week NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 97 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 98 1.3 1.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 99 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 100 2.0 2.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 101 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 102 4.2 4.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 103 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 104 5.9 5.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 105 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 106 4.6 4.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 107 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 108 5.5 5.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 109 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 110 Smokers smoker NNS work_lbjz23isnfbh5bcl4jbmahp6r4 106 111 13 13 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 112 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 113 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 114 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 115 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 116 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 117 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 118 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 119 5 5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 120 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 121 15 15 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 122 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 123 Ethnicity ethnicity NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 124 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 125 Caucasian Caucasian NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 126 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 127 68 68 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 128 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 129 93 93 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 130 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 131 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 132 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 133 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 134 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 135 32 32 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 136 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 137 97 97 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 138 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 139 Systolic systolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 140 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 141 pressure pressure NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 142 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 143 mmHg mmHg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 144 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 145 136 136 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 146 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 147 17 17 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 148 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 149 140 140 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 150 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 151 16 16 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 152 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 153 136 136 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 154 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 155 15 15 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 156 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 157 Diastolic diastolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 158 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 159 pressure pressure NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 160 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 161 mmHg mmHg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 162 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 163 84 84 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 164 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 165 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 166 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 167 88 88 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 168 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 169 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 170 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 171 86 86 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 172 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 173 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 174 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 175 Heart heart NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 176 rate rate NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 177 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 178 bpm bpm NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 179 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 180 78 78 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 181 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 182 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 183 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 184 70 70 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 185 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 186 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 187 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 188 69 69 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 189 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 190 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 191 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 192 CRP CRP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 193 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 194 mg mg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 195 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 196 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 197 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 198 3.59 3.59 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 199 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 200 3.34 3.34 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 201 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 202 3.04 3.04 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 203 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 204 2.07 2.07 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 205 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 206 4.01 4.01 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 207 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 208 3.30 3.30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 209 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 210 Chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 211 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 212 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 106 213 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 214 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 215 51 51 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 216 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 217 69.9 69.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 218 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 219 25 25 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 220 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 221 75.8 75.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 222 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 223 22 22 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 224 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 225 66.7 66.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 226 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 227 Cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 228 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 106 229 total total JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 230 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 231 mmol mmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 232 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 233 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 234 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 235 4.56 4.56 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 236 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 237 1.12 1.12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 238 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 239 5.08 5.08 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 240 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 241 1.72 1.72 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 242 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 243 4.64 4.64 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 244 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 245 1.45 1.45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 246 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 247 HDL hdl NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 248 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 106 249 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 250 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 251 mmol mmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 252 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 253 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 254 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 255 1.35 1.35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 256 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 257 0.71 0.71 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 258 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 259 1.17 1.17 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 260 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 261 0.26 0.26 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 262 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 263 1.50 1.50 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 264 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 265 1.25 1.25 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 266 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 267 LDL LDL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 268 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 106 269 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 270 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 271 mmol mmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 272 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 273 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 274 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 275 2.45 2.45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 276 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 277 0.97 0.97 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 278 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 279 4.02 4.02 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 280 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 281 6.89 6.89 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 282 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 283 2.80 2.80 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 284 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 285 1.00 1.00 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 286 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 287 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 288 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 289 pmol pmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 290 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 291 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 292 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 293 9.46 9.46 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 294 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 295 8.73 8.73 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 296 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 297 8.59 8.59 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 298 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 299 4.96 4.96 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 300 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 301 8.52 8.52 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 302 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 303 5.06 5.06 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 304 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 305 HbA1c HbA1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 306 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 307 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 308 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 309 7.4 7.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 310 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 311 3.2 3.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 312 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 313 6.1 6.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 314 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 315 1.0 1.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 316 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 317 5.9 5.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 318 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 319 0.6 0.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 320 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 321 Triglycerides triglyceride NNS work_lbjz23isnfbh5bcl4jbmahp6r4 106 322 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 323 mmol mmol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 324 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 106 325 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 326 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 327 2.16 2.16 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 328 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 329 1.45 1.45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 330 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 331 2.28 2.28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 332 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 333 1.71 1.71 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 334 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 335 2.11 2.11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 336 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 337 1.37 1.37 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 338 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 339 Waist waist JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 340 circumference circumference NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 341 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 342 cm cm NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 343 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 344 122 122 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 345 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 346 13 13 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 347 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 348 124 124 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 349 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 350 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 351 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 352 127 127 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 353 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 354 19 19 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 355 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 356 No no DT work_lbjz23isnfbh5bcl4jbmahp6r4 106 357 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 358 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 359 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 360 13.7 13.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 361 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 362 14 14 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 363 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 364 42.4 42.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 365 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 366 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 367 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 368 54.5 54.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 369 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 370 Prediabetes Prediabetes NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 371 16 16 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 372 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 373 21.9 21.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 374 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 375 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 376 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 377 30.3 30.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 378 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 379 8 8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 380 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 381 24.2 24.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 382 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 383 Diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 384 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 385 47 47 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 386 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 387 64.4 64.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 388 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 389 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 390 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 391 27.3 27.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 392 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 393 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 394 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 395 21.2 21.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 396 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 397 Treatment Treatment NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 398 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 106 399 OAD OAD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 400 36 36 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 401 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 402 49.3 49.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 403 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 404 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 405 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 406 27.3 27.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 407 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 408 6 6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 409 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 410 18.2 18.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 411 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 412 Antihypertensive antihypertensive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 413 medication medication NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 414 53 53 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 415 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 416 72.6 72.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 417 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 418 16 16 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 419 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 420 48.5 48.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 421 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 422 14 14 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 423 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 424 42.4 42.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 425 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 426 Treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 427 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 106 428 statins statin NNS work_lbjz23isnfbh5bcl4jbmahp6r4 106 429 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 430 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 431 47.9 47.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 432 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 433 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 434 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 435 33.3 33.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 436 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 437 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 438 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 439 21.2 21.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 440 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 441 Antidepressive antidepressive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 442 medication medication NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 443 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 444 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 445 15.1 15.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 446 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 447 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 448 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 449 3.0 3.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 450 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 451 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 452 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 453 3.0 3.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 454 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 455 Antipsychotic antipsychotic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 106 456 medication medication NN work_lbjz23isnfbh5bcl4jbmahp6r4 106 457 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 458 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 459 1.4 1.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 460 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 461 0 0 NFP work_lbjz23isnfbh5bcl4jbmahp6r4 106 462 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 463 0.0 0.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 464 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 465 0 0 NFP work_lbjz23isnfbh5bcl4jbmahp6r4 106 466 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 467 0.0 0.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 106 468 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 469 Variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 106 470 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 106 471 summarized summarize VBN work_lbjz23isnfbh5bcl4jbmahp6r4 106 472 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 106 473 mean mean NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 474 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 106 475 s.d s.d NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 476 . . NNP work_lbjz23isnfbh5bcl4jbmahp6r4 106 477 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 107 1 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 107 2 counts count VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 107 3 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 107 4 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 107 5 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 107 6 if if IN work_lbjz23isnfbh5bcl4jbmahp6r4 107 7 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 107 8 otherwise otherwise RB work_lbjz23isnfbh5bcl4jbmahp6r4 107 9 specified specify VBN work_lbjz23isnfbh5bcl4jbmahp6r4 107 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 108 1 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 108 2 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 108 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 108 4 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 108 5 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 108 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 108 7 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 8 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 9 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 108 11 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 12 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 108 13 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 14 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 15 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 108 16 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 17 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 108 18 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 108 19 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 108 20 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 108 21 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 108 22 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 23 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 24 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 108 25 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 108 26 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 27 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 108 28 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 108 29 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 30 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 108 31 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 108 32 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 108 33 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 34 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 35 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 36 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 37 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 38 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 39 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 108 41 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 108 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 109 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 109 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 109 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 109 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 109 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 109 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 109 9 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 109 10 7199:7 7199:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 109 11 Obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 109 13 especially especially RB work_lbjz23isnfbh5bcl4jbmahp6r4 109 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 109 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 109 16 visceral visceral JJ work_lbjz23isnfbh5bcl4jbmahp6r4 109 17 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 109 19 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 109 20 considered consider VBN work_lbjz23isnfbh5bcl4jbmahp6r4 109 21 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 109 22 driving drive VBG work_lbjz23isnfbh5bcl4jbmahp6r4 109 23 factor factor NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 24 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 109 25 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 109 26 development development NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 27 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 109 28 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 29 resistance resistance NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 30 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 109 31 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 32 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 109 33 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 109 34 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 109 35 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 109 36 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 109 37 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 110 1 Furthermore furthermore RB work_lbjz23isnfbh5bcl4jbmahp6r4 110 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 110 3 visceral visceral JJ work_lbjz23isnfbh5bcl4jbmahp6r4 110 4 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 110 5 evokes evoke VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 110 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 110 7 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 110 8 pro pro JJ work_lbjz23isnfbh5bcl4jbmahp6r4 110 9 - - JJ work_lbjz23isnfbh5bcl4jbmahp6r4 110 10 inflammatory inflammatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 110 11 state state NN work_lbjz23isnfbh5bcl4jbmahp6r4 110 12 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 110 13 36 36 CD work_lbjz23isnfbh5bcl4jbmahp6r4 110 14 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 110 15 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 111 1 Chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 111 2 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 111 3 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 111 4 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 111 5 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 111 6 plays play VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 111 7 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 111 8 important important JJ work_lbjz23isnfbh5bcl4jbmahp6r4 111 9 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 111 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 111 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 111 12 destruction destruction NN work_lbjz23isnfbh5bcl4jbmahp6r4 111 13 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 111 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 111 15 β β NNP work_lbjz23isnfbh5bcl4jbmahp6r4 111 16 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 111 17 cells cell NNS work_lbjz23isnfbh5bcl4jbmahp6r4 111 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 111 19 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 111 20 pancreas pancrea NNS work_lbjz23isnfbh5bcl4jbmahp6r4 111 21 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 111 22 37 37 CD work_lbjz23isnfbh5bcl4jbmahp6r4 111 23 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 111 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 112 1 Concordantly concordantly RB work_lbjz23isnfbh5bcl4jbmahp6r4 112 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 112 3 it -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 112 4 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 112 5 shown show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 112 6 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 112 7 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 112 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 112 9 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 112 10 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 112 11 pathway pathway JJ work_lbjz23isnfbh5bcl4jbmahp6r4 112 12 ameliorates ameliorate NNS work_lbjz23isnfbh5bcl4jbmahp6r4 112 13 glucose glucose VBP work_lbjz23isnfbh5bcl4jbmahp6r4 112 14 metabolism metabolism NN work_lbjz23isnfbh5bcl4jbmahp6r4 112 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 112 16 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 112 17 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 112 18 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 112 19 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 112 20 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 112 21 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 112 22 25 25 CD work_lbjz23isnfbh5bcl4jbmahp6r4 112 23 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 112 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 113 1 There there EX work_lbjz23isnfbh5bcl4jbmahp6r4 113 2 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 113 3 experimental experimental JJ work_lbjz23isnfbh5bcl4jbmahp6r4 113 4 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 113 5 showing show VBG work_lbjz23isnfbh5bcl4jbmahp6r4 113 6 stimulating stimulating JJ work_lbjz23isnfbh5bcl4jbmahp6r4 113 7 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 113 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 113 9 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 113 10 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 113 11 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 113 12 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 113 13 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 113 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 113 15 neurohypophysis neurohypophysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 113 16 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 113 17 27 27 CD work_lbjz23isnfbh5bcl4jbmahp6r4 113 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 113 19 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 113 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 113 21 29 29 CD work_lbjz23isnfbh5bcl4jbmahp6r4 113 22 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 113 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 114 1 Therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 114 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 114 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 114 4 increased increase VBN work_lbjz23isnfbh5bcl4jbmahp6r4 114 5 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 114 6 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 114 7 observed observe VBN work_lbjz23isnfbh5bcl4jbmahp6r4 114 8 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 114 9 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 114 10 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 114 11 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 114 12 might may MD work_lbjz23isnfbh5bcl4jbmahp6r4 114 13 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 114 14 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 114 15 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 114 16 IL-1-driven IL-1-driven `` work_lbjz23isnfbh5bcl4jbmahp6r4 114 17 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 114 18 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 114 19 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 114 20 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 114 21 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 114 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 115 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 115 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 115 3 case case NN work_lbjz23isnfbh5bcl4jbmahp6r4 115 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 115 5 blocking block VBG work_lbjz23isnfbh5bcl4jbmahp6r4 115 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 115 7 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 115 8 pathway pathway NN work_lbjz23isnfbh5bcl4jbmahp6r4 115 9 would would MD work_lbjz23isnfbh5bcl4jbmahp6r4 115 10 lead lead VB work_lbjz23isnfbh5bcl4jbmahp6r4 115 11 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 115 12 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 115 13 reduction reduction NN work_lbjz23isnfbh5bcl4jbmahp6r4 115 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 115 15 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 115 16 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 115 17 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 115 18 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 115 19 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 115 20 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 115 21 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 115 22 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 115 23 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 115 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 116 1 To to IN work_lbjz23isnfbh5bcl4jbmahp6r4 116 2 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 116 3 knowledge knowledge NN work_lbjz23isnfbh5bcl4jbmahp6r4 116 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 116 5 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 116 6 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 116 7 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 116 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 116 9 first first JJ work_lbjz23isnfbh5bcl4jbmahp6r4 116 10 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 116 11 investigate investigate VB work_lbjz23isnfbh5bcl4jbmahp6r4 116 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 116 13 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 116 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 116 15 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 116 16 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 116 17 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 116 18 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 116 19 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 116 20 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 116 21 AVP/ AVP/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 116 22 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 116 23 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 116 24 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 116 25 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 116 26 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 116 27 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 116 28 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 116 29 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 117 1 Interestingly interestingly RB work_lbjz23isnfbh5bcl4jbmahp6r4 117 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 117 3 however however RB work_lbjz23isnfbh5bcl4jbmahp6r4 117 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 117 5 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 117 6 did do VBD work_lbjz23isnfbh5bcl4jbmahp6r4 117 7 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 117 8 observe observe VB work_lbjz23isnfbh5bcl4jbmahp6r4 117 9 any any DT work_lbjz23isnfbh5bcl4jbmahp6r4 117 10 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 117 11 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 117 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 117 13 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 117 14 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 117 15 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 117 16 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 117 17 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 117 18 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 117 19 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 117 20 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 117 21 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 117 22 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 117 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 118 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 118 2 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 118 3 original original JJ work_lbjz23isnfbh5bcl4jbmahp6r4 118 4 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 118 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 118 6 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 118 7 showed show VBD work_lbjz23isnfbh5bcl4jbmahp6r4 118 8 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 118 9 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 118 10 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 118 11 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 118 12 significantly significantly RB work_lbjz23isnfbh5bcl4jbmahp6r4 118 13 down down RB work_lbjz23isnfbh5bcl4jbmahp6r4 118 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 118 15 regulated regulated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 118 16 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 118 17 mirrored mirror VBN work_lbjz23isnfbh5bcl4jbmahp6r4 118 18 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 118 19 CRP CRP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 118 20 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 118 21 interleukin-6 interleukin-6 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 118 22 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 118 23 as as RB work_lbjz23isnfbh5bcl4jbmahp6r4 118 24 early early RB work_lbjz23isnfbh5bcl4jbmahp6r4 118 25 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 118 26 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 118 27 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 118 28 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 118 29 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 118 30 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 118 31 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 118 32 31 31 CD work_lbjz23isnfbh5bcl4jbmahp6r4 118 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 118 34 32 32 CD work_lbjz23isnfbh5bcl4jbmahp6r4 118 35 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 118 36 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 119 1 Despite despite IN work_lbjz23isnfbh5bcl4jbmahp6r4 119 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 119 3 clear clear JJ work_lbjz23isnfbh5bcl4jbmahp6r4 119 4 anti anti JJ work_lbjz23isnfbh5bcl4jbmahp6r4 119 5 - - JJ work_lbjz23isnfbh5bcl4jbmahp6r4 119 6 inflammatory inflammatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 119 7 action action NN work_lbjz23isnfbh5bcl4jbmahp6r4 119 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 119 9 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 119 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 119 11 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 119 12 observed observe VBD work_lbjz23isnfbh5bcl4jbmahp6r4 119 13 no no DT work_lbjz23isnfbh5bcl4jbmahp6r4 119 14 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 119 15 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 119 16 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 119 17 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 119 18 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 120 1 We -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 120 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 120 3 therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 120 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 120 5 conclude conclude VBP work_lbjz23isnfbh5bcl4jbmahp6r4 120 6 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 120 7 systemic systemic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 120 8 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 120 9 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 120 10 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 120 11 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 120 12 major major JJ work_lbjz23isnfbh5bcl4jbmahp6r4 120 13 regulator regulator NN work_lbjz23isnfbh5bcl4jbmahp6r4 120 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 120 15 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 120 16 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 120 17 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 120 18 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 120 19 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 120 20 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 120 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 121 1 Thus thus RB work_lbjz23isnfbh5bcl4jbmahp6r4 121 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 121 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 121 4 question question NN work_lbjz23isnfbh5bcl4jbmahp6r4 121 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 121 6 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 121 7 factor factor NN work_lbjz23isnfbh5bcl4jbmahp6r4 121 8 leads lead VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 121 9 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 121 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 121 11 upregulation upregulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 121 12 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 121 13 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 121 14 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 121 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 121 16 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 121 17 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 121 18 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 121 19 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 121 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 121 21 remains remain VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 121 22 open open JJ work_lbjz23isnfbh5bcl4jbmahp6r4 121 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 122 1 Possibly possibly RB work_lbjz23isnfbh5bcl4jbmahp6r4 122 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 122 3 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 122 4 might may MD work_lbjz23isnfbh5bcl4jbmahp6r4 122 5 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 122 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 122 7 underlying underlie VBG work_lbjz23isnfbh5bcl4jbmahp6r4 122 8 factor factor NN work_lbjz23isnfbh5bcl4jbmahp6r4 122 9 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 122 10 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 122 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 122 12 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 122 13 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 122 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 122 15 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 122 16 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 122 17 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 122 18 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 122 19 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 122 20 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 122 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 123 1 Visceral visceral JJ work_lbjz23isnfbh5bcl4jbmahp6r4 123 2 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 3 represents represent VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 123 4 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 123 5 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 123 6 stress stress NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 7 state state NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 8 leading lead VBG work_lbjz23isnfbh5bcl4jbmahp6r4 123 9 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 123 10 only only RB work_lbjz23isnfbh5bcl4jbmahp6r4 123 11 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 123 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 123 13 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 123 15 proinflammatory proinflammatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 123 16 cytokines cytokine NNS work_lbjz23isnfbh5bcl4jbmahp6r4 123 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 123 18 38 38 CD work_lbjz23isnfbh5bcl4jbmahp6r4 123 19 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 123 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 123 21 but but CC work_lbjz23isnfbh5bcl4jbmahp6r4 123 22 also also RB work_lbjz23isnfbh5bcl4jbmahp6r4 123 23 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 123 24 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 123 25 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 123 26 activation activation NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 27 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 123 28 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 123 29 sympathetic sympathetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 123 30 nervous nervous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 123 31 system system NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 32 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 123 33 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 123 34 most most RBS work_lbjz23isnfbh5bcl4jbmahp6r4 123 35 obviously obviously RB work_lbjz23isnfbh5bcl4jbmahp6r4 123 36 mirrored mirror VBN work_lbjz23isnfbh5bcl4jbmahp6r4 123 37 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 123 38 elevation elevation NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 39 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 123 40 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 41 pressure pressure NN work_lbjz23isnfbh5bcl4jbmahp6r4 123 42 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 123 43 39 39 CD work_lbjz23isnfbh5bcl4jbmahp6r4 123 44 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 123 45 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 124 1 Activation activation NN work_lbjz23isnfbh5bcl4jbmahp6r4 124 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 124 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 124 4 sympathetic sympathetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 124 5 nervous nervous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 124 6 system system NN work_lbjz23isnfbh5bcl4jbmahp6r4 124 7 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 124 8 recognized recognize VBN work_lbjz23isnfbh5bcl4jbmahp6r4 124 9 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 124 10 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 124 11 non non JJ work_lbjz23isnfbh5bcl4jbmahp6r4 124 12 - - JJ work_lbjz23isnfbh5bcl4jbmahp6r4 124 13 osmotic osmotic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 124 14 stimulus stimulus NN work_lbjz23isnfbh5bcl4jbmahp6r4 124 15 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 124 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 124 17 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 124 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 124 19 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 124 20 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 124 21 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 124 22 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 124 23 40 40 CD work_lbjz23isnfbh5bcl4jbmahp6r4 124 24 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 124 25 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 125 1 Therefore therefore RB work_lbjz23isnfbh5bcl4jbmahp6r4 125 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 125 3 it -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 125 4 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 125 5 possible possible JJ work_lbjz23isnfbh5bcl4jbmahp6r4 125 6 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 125 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 125 8 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 125 9 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 125 10 stress stress NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 11 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 125 12 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 13 increases increase VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 125 14 AVP/ AVP/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 125 15 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 16 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 125 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 125 18 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 125 19 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 125 20 mediated mediate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 125 21 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 125 22 sympathetic sympathetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 125 23 nervous nervous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 125 24 Figure figure NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 25   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 125 26 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 125 27 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 125 28 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 29 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 125 30 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 31 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 125 32 Log Log NNP work_lbjz23isnfbh5bcl4jbmahp6r4 125 33 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 125 34 transformed transform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 125 35 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 125 36 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 125 37 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 125 38 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 125 39 different different JJ work_lbjz23isnfbh5bcl4jbmahp6r4 125 40 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 125 41 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 126 1 Log log NN work_lbjz23isnfbh5bcl4jbmahp6r4 126 2 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 126 3 transformed transform VBN work_lbjz23isnfbh5bcl4jbmahp6r4 126 4 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 126 5 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 126 6 measured measure VBN work_lbjz23isnfbh5bcl4jbmahp6r4 126 7 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 126 8 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 126 9 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 126 10 shown show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 126 11 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 126 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 126 13 y y NN work_lbjz23isnfbh5bcl4jbmahp6r4 126 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 126 15 axis axis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 126 16 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 126 17 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 126 18 different different JJ work_lbjz23isnfbh5bcl4jbmahp6r4 126 19 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 126 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 127 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 127 2 A a DT work_lbjz23isnfbh5bcl4jbmahp6r4 127 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 127 4 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 127 5 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 127 6 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 127 7 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 127 8 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 127 9 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 127 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 127 11 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 127 12 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 127 13 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 127 14 defined define VBN work_lbjz23isnfbh5bcl4jbmahp6r4 127 15 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 127 16 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 127 17 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 127 18 reactive reactive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 127 19 protein protein NN work_lbjz23isnfbh5bcl4jbmahp6r4 127 20 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 127 21 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 127 22 < < NNP work_lbjz23isnfbh5bcl4jbmahp6r4 127 23 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 127 24 ≥2 ≥2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 127 25 mg mg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 127 26 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 127 27 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 127 28 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 127 29 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 127 30 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 128 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 128 2 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 128 4 Diabetic diabetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 128 5 status status NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 6 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 128 7 determined determine VBN work_lbjz23isnfbh5bcl4jbmahp6r4 128 8 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 128 9 medical medical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 128 10 history history NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 11 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 128 12 HbA1c HbA1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 128 13 cut cut NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 128 15 offs off NNS work_lbjz23isnfbh5bcl4jbmahp6r4 128 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 128 17 ≥6.5 ≥6.5 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 128 18 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 19 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 128 20 overt overt JJ work_lbjz23isnfbh5bcl4jbmahp6r4 128 21 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 22 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 128 23 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 24 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 128 25 5.7–6.4 5.7–6.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 128 26 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 128 27 defined define VBN work_lbjz23isnfbh5bcl4jbmahp6r4 128 28 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 128 29 prediabetes prediabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 128 30 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 129 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 129 2 C c NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 3 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 129 4 D d NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 5 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 129 6 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 129 7 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 129 8 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 129 9 without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 129 10 any any DT work_lbjz23isnfbh5bcl4jbmahp6r4 129 11 antihypertensive antihypertensive NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 12 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 129 13 C c NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 14 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 129 15 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 129 16 lipid lipid NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 17 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 129 18 lowering lowering NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 19 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 129 20 D d NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 21 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 129 22 medication medication NN work_lbjz23isnfbh5bcl4jbmahp6r4 129 23 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 129 24 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 129 25 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 130 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 130 2 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 130 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 130 4 Subgroup Subgroup NNP work_lbjz23isnfbh5bcl4jbmahp6r4 130 5 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 130 6 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 130 7 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 130 8 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 130 9 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 130 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 131 1 * * NFP work_lbjz23isnfbh5bcl4jbmahp6r4 131 2 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 131 3     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 131 4 < < NN work_lbjz23isnfbh5bcl4jbmahp6r4 131 5     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 131 6 0.05 0.05 CD work_lbjz23isnfbh5bcl4jbmahp6r4 131 7 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 131 8 * * NFP work_lbjz23isnfbh5bcl4jbmahp6r4 131 9 * * NFP work_lbjz23isnfbh5bcl4jbmahp6r4 131 10 P p NN work_lbjz23isnfbh5bcl4jbmahp6r4 131 11     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 131 12 < < XX work_lbjz23isnfbh5bcl4jbmahp6r4 131 13     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 131 14 0.01 0.01 CD work_lbjz23isnfbh5bcl4jbmahp6r4 131 15 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 132 1 Figure figure NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 2   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 132 3 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 132 4 Change change NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 132 6 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 132 7 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 132 8 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 132 9 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 10 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 132 11 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 132 12 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 13 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 14 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 132 15 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 132 16 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 132 17 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 18 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 132 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 132 20 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 132 21 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 132 22 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 132 23 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 132 24 subtracted subtract VBN work_lbjz23isnfbh5bcl4jbmahp6r4 132 25 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 132 26 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 27 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 132 28 split split VBD work_lbjz23isnfbh5bcl4jbmahp6r4 132 29 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 132 30 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 132 31 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 132 32 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 33 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 132 34 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 133 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 133 2 difference difference NN work_lbjz23isnfbh5bcl4jbmahp6r4 133 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 133 4 depicted depict VBN work_lbjz23isnfbh5bcl4jbmahp6r4 133 5 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 133 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 133 7 y y NN work_lbjz23isnfbh5bcl4jbmahp6r4 133 8 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 133 9 axis axis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 133 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 134 1 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 134 2 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 134 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 134 4 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 134 5 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 134 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 134 7 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 8 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 9 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 134 11 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 12 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 134 13 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 14 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 15 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 134 16 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 17 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 134 18 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 134 19 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 134 20 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 134 21 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 134 22 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 23 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 24 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 134 25 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 134 26 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 27 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 134 28 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 134 29 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 30 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 134 31 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 134 32 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 134 33 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 34 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 35 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 36 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 37 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 38 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 39 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 134 41 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 134 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 135 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 135 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 135 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 135 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 135 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 135 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 135 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 135 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 135 9 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 135 10 720 720 CD work_lbjz23isnfbh5bcl4jbmahp6r4 135 11 PB PB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 135 12 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 135 13 XX xx NN work_lbjz23isnfbh5bcl4jbmahp6r4 135 14 9:7 9:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 135 15 activity activity NN work_lbjz23isnfbh5bcl4jbmahp6r4 135 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 136 1 Interestingly interestingly RB work_lbjz23isnfbh5bcl4jbmahp6r4 136 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 136 3 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 136 4 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 136 5 support support NN work_lbjz23isnfbh5bcl4jbmahp6r4 136 6 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 136 7 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 136 8 hypothesis hypothesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 136 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 136 10 Loncar Loncar NNP work_lbjz23isnfbh5bcl4jbmahp6r4 136 11 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 136 12   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 136 13 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 136 14 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 137 1 reported report VBD work_lbjz23isnfbh5bcl4jbmahp6r4 137 2 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 137 3 reduction reduction NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 4 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 137 5 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 137 6 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 137 7 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 137 8 initiation initiation NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 137 10 beta beta NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 11 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 137 12 blockade blockade NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 13 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 14 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 137 15 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 137 16 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 137 17 heart heart NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 18 failure failure NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 19 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 137 20 reduced reduced JJ work_lbjz23isnfbh5bcl4jbmahp6r4 137 21 ejection ejection NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 22 fraction fraction NN work_lbjz23isnfbh5bcl4jbmahp6r4 137 23 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 137 24 41 41 CD work_lbjz23isnfbh5bcl4jbmahp6r4 137 25 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 137 26 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 138 1 As as IN work_lbjz23isnfbh5bcl4jbmahp6r4 138 2 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 138 3 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 138 4 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 138 5 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 138 6 already already RB work_lbjz23isnfbh5bcl4jbmahp6r4 138 7 obese obese JJ work_lbjz23isnfbh5bcl4jbmahp6r4 138 8 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 138 9 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 138 10 inclusion inclusion NN work_lbjz23isnfbh5bcl4jbmahp6r4 138 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 138 12 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 138 13 can can MD work_lbjz23isnfbh5bcl4jbmahp6r4 138 14 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 138 15 conclude conclude VB work_lbjz23isnfbh5bcl4jbmahp6r4 138 16 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 138 17 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 138 18 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 138 19 whether whether IN work_lbjz23isnfbh5bcl4jbmahp6r4 138 20 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 138 21 per per FW work_lbjz23isnfbh5bcl4jbmahp6r4 138 22 se se FW work_lbjz23isnfbh5bcl4jbmahp6r4 138 23 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 138 24 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 138 25 driving drive VBG work_lbjz23isnfbh5bcl4jbmahp6r4 138 26 force force NN work_lbjz23isnfbh5bcl4jbmahp6r4 138 27 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 138 28 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 138 29 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 138 30 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 138 31 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 139 1 To to TO work_lbjz23isnfbh5bcl4jbmahp6r4 139 2 investigate investigate VB work_lbjz23isnfbh5bcl4jbmahp6r4 139 3 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 139 4 hypothesis hypothesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 139 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 139 6 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 139 7 before before IN work_lbjz23isnfbh5bcl4jbmahp6r4 139 8 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 139 9 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 139 10 weight weight NN work_lbjz23isnfbh5bcl4jbmahp6r4 139 11 gain gain NN work_lbjz23isnfbh5bcl4jbmahp6r4 139 12 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 139 13 overfeeding overfeeding NN work_lbjz23isnfbh5bcl4jbmahp6r4 139 14 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 139 15 lack lack NN work_lbjz23isnfbh5bcl4jbmahp6r4 139 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 139 17 physical physical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 139 18 exercise exercise NN work_lbjz23isnfbh5bcl4jbmahp6r4 139 19 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 139 20 required require VBN work_lbjz23isnfbh5bcl4jbmahp6r4 139 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 140 1 However however RB work_lbjz23isnfbh5bcl4jbmahp6r4 140 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 140 3 surprisingly surprisingly RB work_lbjz23isnfbh5bcl4jbmahp6r4 140 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 140 5 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 140 6 found find VBD work_lbjz23isnfbh5bcl4jbmahp6r4 140 7 only only RB work_lbjz23isnfbh5bcl4jbmahp6r4 140 8 one one CD work_lbjz23isnfbh5bcl4jbmahp6r4 140 9 abstract abstract JJ work_lbjz23isnfbh5bcl4jbmahp6r4 140 10 reporting reporting NN work_lbjz23isnfbh5bcl4jbmahp6r4 140 11 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 140 12 results result NNS work_lbjz23isnfbh5bcl4jbmahp6r4 140 13 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 140 14 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 140 15 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 140 16 before before IN work_lbjz23isnfbh5bcl4jbmahp6r4 140 17 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 140 18 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 140 19 weight weight NN work_lbjz23isnfbh5bcl4jbmahp6r4 140 20 loss loss NN work_lbjz23isnfbh5bcl4jbmahp6r4 140 21 so so RB work_lbjz23isnfbh5bcl4jbmahp6r4 140 22 far far RB work_lbjz23isnfbh5bcl4jbmahp6r4 140 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 141 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 141 3 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 4 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 5 Aktimur Aktimur NNP work_lbjz23isnfbh5bcl4jbmahp6r4 141 6 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 141 7     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 141 8 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 141 9 . . NNP work_lbjz23isnfbh5bcl4jbmahp6r4 141 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 141 11 weight weight NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 12 loss loss NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 13 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 141 14 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 15 bariatric bariatric JJ work_lbjz23isnfbh5bcl4jbmahp6r4 141 16 surgery surgery NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 17 led lead VBD work_lbjz23isnfbh5bcl4jbmahp6r4 141 18 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 19 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 141 20 significant significant JJ work_lbjz23isnfbh5bcl4jbmahp6r4 141 21 decrease decrease NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 22 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 23 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 141 24 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 141 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 141 26 arguing argue VBG work_lbjz23isnfbh5bcl4jbmahp6r4 141 27 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 28 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 141 29 causal causal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 141 30 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 31 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 32 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 33 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 141 34 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 141 35 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 141 36 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 141 37 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 141 38 42 42 CD work_lbjz23isnfbh5bcl4jbmahp6r4 141 39 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 141 40 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 142 1 Nevertheless nevertheless RB work_lbjz23isnfbh5bcl4jbmahp6r4 142 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 142 3 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 142 4 bidirectional bidirectional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 142 5 relationship relationship NN work_lbjz23isnfbh5bcl4jbmahp6r4 142 6 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 142 7 elevated elevated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 142 8 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 142 9 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 142 10 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 142 11 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 142 12 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 142 13 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 142 14 needs need VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 142 15 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 142 16 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 142 17 considered consider VBN work_lbjz23isnfbh5bcl4jbmahp6r4 142 18 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 143 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 143 2 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 143 3 regard regard NN work_lbjz23isnfbh5bcl4jbmahp6r4 143 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 143 5 Enhörning Enhörning NNP work_lbjz23isnfbh5bcl4jbmahp6r4 143 6 et et FW work_lbjz23isnfbh5bcl4jbmahp6r4 143 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 143 8 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 143 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 144 1 showed show VBN work_lbjz23isnfbh5bcl4jbmahp6r4 144 2 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 144 3 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 144 4 longitudinal longitudinal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 144 5 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 6 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 144 7 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 144 8 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 9 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 144 10 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 144 11 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 144 12 predicted predict VBD work_lbjz23isnfbh5bcl4jbmahp6r4 144 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 144 14 development development NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 144 16 abdominal abdominal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 144 17 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 144 19 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 20 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 144 21 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 22 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 144 23 15.8 15.8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 144 24 years year NNS work_lbjz23isnfbh5bcl4jbmahp6r4 144 25 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 144 26 follow follow NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 27 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 144 28 up up NN work_lbjz23isnfbh5bcl4jbmahp6r4 144 29 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 144 30 6 6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 144 31 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 144 32 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 145 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 145 2 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 145 3 suggested suggest VBD work_lbjz23isnfbh5bcl4jbmahp6r4 145 4 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 5 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 145 6 might may MD work_lbjz23isnfbh5bcl4jbmahp6r4 145 7 play play VB work_lbjz23isnfbh5bcl4jbmahp6r4 145 8 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 145 9 causal causal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 145 10 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 145 11 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 145 13 development development NN work_lbjz23isnfbh5bcl4jbmahp6r4 145 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 15 these these DT work_lbjz23isnfbh5bcl4jbmahp6r4 145 16 two two CD work_lbjz23isnfbh5bcl4jbmahp6r4 145 17 conditions condition NNS work_lbjz23isnfbh5bcl4jbmahp6r4 145 18 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 19 enhancing enhance VBG work_lbjz23isnfbh5bcl4jbmahp6r4 145 20 gluconeogenesis gluconeogenesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 145 21 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 145 22 glycogenolysis glycogenolysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 145 23 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 24 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 145 25 liver liver NN work_lbjz23isnfbh5bcl4jbmahp6r4 145 26 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 27 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 145 28 1a 1a NNP work_lbjz23isnfbh5bcl4jbmahp6r4 145 29 receptors receptor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 145 30 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 145 31 43 43 CD work_lbjz23isnfbh5bcl4jbmahp6r4 145 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 145 33 44 44 CD work_lbjz23isnfbh5bcl4jbmahp6r4 145 34 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 145 35 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 145 36 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 145 37 antilipolytic antilipolytic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 145 38 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 145 39 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 145 40 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 145 41 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 145 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 146 1 Furthermore furthermore RB work_lbjz23isnfbh5bcl4jbmahp6r4 146 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 146 3 it -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 146 4 might may MD work_lbjz23isnfbh5bcl4jbmahp6r4 146 5 lead lead VB work_lbjz23isnfbh5bcl4jbmahp6r4 146 6 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 146 7 hyperinsulinemia hyperinsulinemia NN work_lbjz23isnfbh5bcl4jbmahp6r4 146 8 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 146 9 activation activation NN work_lbjz23isnfbh5bcl4jbmahp6r4 146 10 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 146 11 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 146 12 1b 1b NNP work_lbjz23isnfbh5bcl4jbmahp6r4 146 13 Table Table NNP work_lbjz23isnfbh5bcl4jbmahp6r4 146 14 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 146 15     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 146 16 Effects Effects NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 146 17 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 146 18 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 146 19 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 146 20 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 146 21 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 146 22 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 146 23 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 146 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 147 1 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 2 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 3 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 4 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 147 5 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 7 Anakinra Anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 8 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 9 n n CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 10     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 11 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 147 12     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 13 106 106 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 147 15 n n CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 16     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 17 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 147 18     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 19 73 73 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 20 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 147 21 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 22 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 23 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 147 24 n n NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 25     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 26 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 147 27     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 28 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 29 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 147 30 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 31 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 32 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 33 Placebo Placebo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 34 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 35 n n CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 36     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 37 = = SYM work_lbjz23isnfbh5bcl4jbmahp6r4 147 38     _SP work_lbjz23isnfbh5bcl4jbmahp6r4 147 39 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 40 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 147 41 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 42 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 43 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 44 Absolute absolute JJ work_lbjz23isnfbh5bcl4jbmahp6r4 147 45 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 147 46 Change change NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 47 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 147 48 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 147 49 Absolute absolute JJ work_lbjz23isnfbh5bcl4jbmahp6r4 147 50 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 147 51 Change change NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 52 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 147 53 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 147 54 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 55 7.0 7.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 56 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 57 4.2–11.2 4.2–11.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 58 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 59 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 147 60 7.2 7.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 61 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 62 5.4–10.1 5.4–10.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 63 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 64 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 147 65 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 66 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 67 7.5 7.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 68 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 69 3.9–11.5 3.9–11.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 70 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 71 0.1 0.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 72 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 73 −1.1–1.6 −1.1–1.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 74 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 75 7.5 7.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 76 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 77 6.2–10.4 6.2–10.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 78 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 79 0.1 0.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 80 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 81 −0.7–1.1 −0.7–1.1 ADD work_lbjz23isnfbh5bcl4jbmahp6r4 147 82 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 83 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 84 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 85 8.6 8.6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 86 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 87 5.7–10.4 5.7–10.4 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 88 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 89 0.7 0.7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 90 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 91 −0.8–1.7 −0.8–1.7 NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 92 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 93 7.2 7.2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 94 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 95 5.6–10.0 5.6–10.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 96 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 97 −0.2 −0.2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 98 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 99 −1.9–1.5 −1.9–1.5 NFP work_lbjz23isnfbh5bcl4jbmahp6r4 147 100 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 101 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 102 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 103 7.5 7.5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 104 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 105 5.3–10.4 5.3–10.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 106 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 107 −0.3 −0.3 NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 108 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 109 −2.2–1.8 −2.2–1.8 NN work_lbjz23isnfbh5bcl4jbmahp6r4 147 110 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 111 7.9 7.9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 112 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 113 5.7–9.3 5.7–9.3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 114 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 115 0.1 0.1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 147 116 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 117 −1.8–1.4 −1.8–1.4 ADD work_lbjz23isnfbh5bcl4jbmahp6r4 147 118 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 119 Variables variable NNS work_lbjz23isnfbh5bcl4jbmahp6r4 147 120 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 147 121 summarized summarize VBN work_lbjz23isnfbh5bcl4jbmahp6r4 147 122 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 147 123 medians median NNS work_lbjz23isnfbh5bcl4jbmahp6r4 147 124 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 125 IQR IQR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 147 126 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 147 127 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 148 1 For for IN work_lbjz23isnfbh5bcl4jbmahp6r4 148 2 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 148 3 rows row NNS work_lbjz23isnfbh5bcl4jbmahp6r4 148 4 ‘ ' `` work_lbjz23isnfbh5bcl4jbmahp6r4 148 5 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 148 6 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 148 7 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 148 8 ‘ ' `` work_lbjz23isnfbh5bcl4jbmahp6r4 148 9 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 148 10 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 148 11 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 148 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 148 13 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 148 14 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 148 15 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 148 16 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 148 17 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 148 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 148 19 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 148 20 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 148 21 included include VBN work_lbjz23isnfbh5bcl4jbmahp6r4 148 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 149 1 For for IN work_lbjz23isnfbh5bcl4jbmahp6r4 149 2 ‘ ' `` work_lbjz23isnfbh5bcl4jbmahp6r4 149 3 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 149 4 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 149 5 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 149 6 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 149 7 ‘ ' `` work_lbjz23isnfbh5bcl4jbmahp6r4 149 8 Day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 149 9 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 149 10 ’ ' '' work_lbjz23isnfbh5bcl4jbmahp6r4 149 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 149 12 only only RB work_lbjz23isnfbh5bcl4jbmahp6r4 149 13 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 149 14 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 149 15 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 149 16 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 149 17 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 149 18 available available JJ work_lbjz23isnfbh5bcl4jbmahp6r4 149 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 150 1 Figure figure NN work_lbjz23isnfbh5bcl4jbmahp6r4 150 2   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 150 3 3 3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 150 4 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 150 5 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 150 6 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 150 7 D d NN work_lbjz23isnfbh5bcl4jbmahp6r4 150 8 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 150 9 Change change NN work_lbjz23isnfbh5bcl4jbmahp6r4 150 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 150 11 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 150 12 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 150 13 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 150 14 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 150 15 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 150 16 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 150 17 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 150 18 group group NNP work_lbjz23isnfbh5bcl4jbmahp6r4 150 19 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 150 20 subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 150 21 analyses analysis NNS work_lbjz23isnfbh5bcl4jbmahp6r4 150 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 151 1 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 151 2 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 151 3 divided divide VBN work_lbjz23isnfbh5bcl4jbmahp6r4 151 4 into into IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 5 subgroups subgroup NNS work_lbjz23isnfbh5bcl4jbmahp6r4 151 6 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 151 7 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 151 9 presence presence NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 10 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 11 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 12 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 13 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 14 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 15 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 16 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 151 17 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 18 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 151 20 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 21 defined define VBN work_lbjz23isnfbh5bcl4jbmahp6r4 151 22 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 23 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 24 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 151 25 reactive reactive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 26 protein protein NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 27 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 151 28 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 29 < < NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 30 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 151 31 ≥2 ≥2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 32 mg mg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 33 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 151 34 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 35 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 36 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 37 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 151 38 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 39 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 40 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 41 diabetic diabetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 42 status status NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 43 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 44 baseline baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 45 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 151 46 was be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 151 47 determined determine VBN work_lbjz23isnfbh5bcl4jbmahp6r4 151 48 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 49 medical medical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 50 history history NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 51 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 151 52 HbA1c HbA1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 53 cut cut NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 54 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 151 55 offs off NNS work_lbjz23isnfbh5bcl4jbmahp6r4 151 56 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 151 57 ≥6.5 ≥6.5 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 58 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 59 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 60 overt overt JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 61 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 62 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 151 63 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 64 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 151 65 5.7–6.4 5.7–6.4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 151 66 % % NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 67 defined define VBN work_lbjz23isnfbh5bcl4jbmahp6r4 151 68 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 69 prediabetes prediabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 151 70 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 151 71 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 72 C c NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 73 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 74 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 151 75 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 76 BMI BMI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 77 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 78 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 79 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 151 80 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 81 D d NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 82 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 83 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 151 84 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 85 baseline baseline JJ work_lbjz23isnfbh5bcl4jbmahp6r4 151 86 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 151 87 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 151 88 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 151 89 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 151 90 highest high JJS work_lbjz23isnfbh5bcl4jbmahp6r4 151 91 tertile tertile NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 92 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 93 ≥9.4 ≥9.4 NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 94 pmol pmol NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 95 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 151 96 L l NN work_lbjz23isnfbh5bcl4jbmahp6r4 151 97 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 151 98 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 152 1 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 152 2 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 152 3 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 152 4 day day NN work_lbjz23isnfbh5bcl4jbmahp6r4 152 5 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 152 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 152 7 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 152 8 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 152 9 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 152 10 were be VBD work_lbjz23isnfbh5bcl4jbmahp6r4 152 11 subtracted subtract VBN work_lbjz23isnfbh5bcl4jbmahp6r4 152 12 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 152 13 baseline baseline NN work_lbjz23isnfbh5bcl4jbmahp6r4 152 14 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 152 15 split split VBD work_lbjz23isnfbh5bcl4jbmahp6r4 152 16 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 152 17 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 152 18 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 152 19 treatment treatment NN work_lbjz23isnfbh5bcl4jbmahp6r4 152 20 group group NN work_lbjz23isnfbh5bcl4jbmahp6r4 152 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 153 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 153 2 difference difference NN work_lbjz23isnfbh5bcl4jbmahp6r4 153 3 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 153 4 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 153 5 values value NNS work_lbjz23isnfbh5bcl4jbmahp6r4 153 6 according accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 153 7 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 153 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 153 9 subgroup subgroup NN work_lbjz23isnfbh5bcl4jbmahp6r4 153 10 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 153 11 depicted depict VBN work_lbjz23isnfbh5bcl4jbmahp6r4 153 12 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 153 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 153 14 y y NN work_lbjz23isnfbh5bcl4jbmahp6r4 153 15 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 153 16 axis axis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 153 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 154 1 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 154 2 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 154 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 154 4 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 154 5 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 154 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 154 7 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 8 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 9 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 154 11 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 12 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 154 13 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 14 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 15 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 154 16 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 17 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 154 18 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 154 19 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 154 20 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 154 21 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 154 22 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 23 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 24 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 154 25 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 154 26 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 27 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 154 28 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 154 29 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 30 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 154 31 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 154 32 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 154 33 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 34 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 35 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 36 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 37 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 38 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 39 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 154 41 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 154 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 155 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 155 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 155 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 155 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 155 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 155 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 155 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 155 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 155 9 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 155 10 7219:7 7219:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 155 11 receptors receptor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 155 12 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 155 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 155 14 pancreas pancrea NNS work_lbjz23isnfbh5bcl4jbmahp6r4 155 15 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 155 16 45 45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 155 17 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 155 18 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 156 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 156 2 summary summary NN work_lbjz23isnfbh5bcl4jbmahp6r4 156 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 156 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 156 5 available available JJ work_lbjz23isnfbh5bcl4jbmahp6r4 156 6 evidence evidence NN work_lbjz23isnfbh5bcl4jbmahp6r4 156 7 suggests suggest VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 156 8 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 156 9 bidirectional bidirectional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 156 10 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 156 11 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 156 12 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 156 13 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 156 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 156 15 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 156 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 156 17 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 156 18 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 156 19 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 156 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 157 1 According accord VBG work_lbjz23isnfbh5bcl4jbmahp6r4 157 2 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 157 3 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 157 4 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 157 6 however however RB work_lbjz23isnfbh5bcl4jbmahp6r4 157 7 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 157 8 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 9 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 157 11 grade grade NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 12 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 13 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 157 14 probably probably RB work_lbjz23isnfbh5bcl4jbmahp6r4 157 15 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 157 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 157 17 driving drive VBG work_lbjz23isnfbh5bcl4jbmahp6r4 157 18 force force NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 19 behind behind IN work_lbjz23isnfbh5bcl4jbmahp6r4 157 20 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 157 21 elevation elevation NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 22 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 157 23 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 157 24 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 157 25 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 157 26 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 157 27 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 157 28 other other JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 29 mechanisms mechanism NNS work_lbjz23isnfbh5bcl4jbmahp6r4 157 30 such such JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 31 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 157 32 sympathetic sympathetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 33 nervous nervous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 34 system system NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 35 activation activation NN work_lbjz23isnfbh5bcl4jbmahp6r4 157 36 must must MD work_lbjz23isnfbh5bcl4jbmahp6r4 157 37 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 157 38 investigated investigate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 157 39 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 157 40 future future JJ work_lbjz23isnfbh5bcl4jbmahp6r4 157 41 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 157 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 158 1 Strengths strength NNS work_lbjz23isnfbh5bcl4jbmahp6r4 158 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 158 3 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 158 4 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 158 5 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 158 6 first first JJ work_lbjz23isnfbh5bcl4jbmahp6r4 158 7 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 158 8 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 158 9 used use VBD work_lbjz23isnfbh5bcl4jbmahp6r4 158 10 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 158 11 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 158 12 interventional interventional JJ work_lbjz23isnfbh5bcl4jbmahp6r4 158 13 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 158 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 158 15 one one CD work_lbjz23isnfbh5bcl4jbmahp6r4 158 16 being be VBG work_lbjz23isnfbh5bcl4jbmahp6r4 158 17 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 158 18 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 158 19 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 158 20 controlled control VBN work_lbjz23isnfbh5bcl4jbmahp6r4 158 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 158 22 double double JJ work_lbjz23isnfbh5bcl4jbmahp6r4 158 23 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 158 24 blinded blinded JJ work_lbjz23isnfbh5bcl4jbmahp6r4 158 25 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 158 26 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 158 27 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 158 28 spares spare VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 158 29 questions question NNS work_lbjz23isnfbh5bcl4jbmahp6r4 158 30 about about IN work_lbjz23isnfbh5bcl4jbmahp6r4 158 31 association association NN work_lbjz23isnfbh5bcl4jbmahp6r4 158 32 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 158 33 causality causality NN work_lbjz23isnfbh5bcl4jbmahp6r4 158 34 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 159 1 Second second JJ work_lbjz23isnfbh5bcl4jbmahp6r4 159 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 159 3 we -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 159 4 investigated investigate VBD work_lbjz23isnfbh5bcl4jbmahp6r4 159 5 short- short- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 159 6 term term NN work_lbjz23isnfbh5bcl4jbmahp6r4 159 7 as as RB work_lbjz23isnfbh5bcl4jbmahp6r4 159 8 well well RB work_lbjz23isnfbh5bcl4jbmahp6r4 159 9 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 159 10 longer long JJR work_lbjz23isnfbh5bcl4jbmahp6r4 159 11 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 159 12 term term NN work_lbjz23isnfbh5bcl4jbmahp6r4 159 13 effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 159 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 159 15 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 159 16 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 159 17 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 159 18 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 159 19 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 159 20 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 159 21 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 159 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 160 1 Third third JJ work_lbjz23isnfbh5bcl4jbmahp6r4 160 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 160 3 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 160 4 studies study NNS work_lbjz23isnfbh5bcl4jbmahp6r4 160 5 had have VBD work_lbjz23isnfbh5bcl4jbmahp6r4 160 6 similar similar JJ work_lbjz23isnfbh5bcl4jbmahp6r4 160 7 eligibility eligibility NN work_lbjz23isnfbh5bcl4jbmahp6r4 160 8 criteria criterion NNS work_lbjz23isnfbh5bcl4jbmahp6r4 160 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 160 10 visit visit VB work_lbjz23isnfbh5bcl4jbmahp6r4 160 11 procedures procedure NNS work_lbjz23isnfbh5bcl4jbmahp6r4 160 12 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 161 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 161 2 both both DT work_lbjz23isnfbh5bcl4jbmahp6r4 161 3 trials trial NNS work_lbjz23isnfbh5bcl4jbmahp6r4 161 4 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 161 5 had have VBD work_lbjz23isnfbh5bcl4jbmahp6r4 161 6 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 161 7 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 161 8 fasting fast VBG work_lbjz23isnfbh5bcl4jbmahp6r4 161 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 161 10 refrain refrain VB work_lbjz23isnfbh5bcl4jbmahp6r4 161 11 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 161 12 drinking drink VBG work_lbjz23isnfbh5bcl4jbmahp6r4 161 13 water water NN work_lbjz23isnfbh5bcl4jbmahp6r4 161 14 before before IN work_lbjz23isnfbh5bcl4jbmahp6r4 161 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 161 16 morning morning NN work_lbjz23isnfbh5bcl4jbmahp6r4 161 17 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 161 18 samplings sampling NNS work_lbjz23isnfbh5bcl4jbmahp6r4 161 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 161 20 rendering render VBG work_lbjz23isnfbh5bcl4jbmahp6r4 161 21 reliable reliable JJ work_lbjz23isnfbh5bcl4jbmahp6r4 161 22 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 161 23 measurements measurement NNS work_lbjz23isnfbh5bcl4jbmahp6r4 161 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 162 1 Limitations limitation NNS work_lbjz23isnfbh5bcl4jbmahp6r4 162 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 162 3 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 162 4 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 162 5 include include VBP work_lbjz23isnfbh5bcl4jbmahp6r4 162 6 that that IN work_lbjz23isnfbh5bcl4jbmahp6r4 162 7 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 162 8 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 162 9 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 162 10 secondary secondary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 162 11 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 162 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 162 13 which which WDT work_lbjz23isnfbh5bcl4jbmahp6r4 162 14 always always RB work_lbjz23isnfbh5bcl4jbmahp6r4 162 15 bears bear VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 162 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 162 17 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 162 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 162 19 insufficient insufficient JJ work_lbjz23isnfbh5bcl4jbmahp6r4 162 20 power power NN work_lbjz23isnfbh5bcl4jbmahp6r4 162 21 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 162 22 this this DT work_lbjz23isnfbh5bcl4jbmahp6r4 162 23 endpoint endpoint NN work_lbjz23isnfbh5bcl4jbmahp6r4 162 24 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 163 1 Nevertheless nevertheless RB work_lbjz23isnfbh5bcl4jbmahp6r4 163 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 163 3 no no DT work_lbjz23isnfbh5bcl4jbmahp6r4 163 4 tendency tendency NN work_lbjz23isnfbh5bcl4jbmahp6r4 163 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 163 6 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 163 7 decrease decrease NN work_lbjz23isnfbh5bcl4jbmahp6r4 163 8 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 163 9 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 163 10 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 163 11 can can MD work_lbjz23isnfbh5bcl4jbmahp6r4 163 12 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 163 13 observed observe VBN work_lbjz23isnfbh5bcl4jbmahp6r4 163 14 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 163 15 our -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 163 16 data datum NNS work_lbjz23isnfbh5bcl4jbmahp6r4 163 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 164 1 Alternatively alternatively RB work_lbjz23isnfbh5bcl4jbmahp6r4 164 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 164 3 another another DT work_lbjz23isnfbh5bcl4jbmahp6r4 164 4 cytokine cytokine NN work_lbjz23isnfbh5bcl4jbmahp6r4 164 5 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 164 6 e.g. e.g. RB work_lbjz23isnfbh5bcl4jbmahp6r4 165 1 tumor tumor NNP work_lbjz23isnfbh5bcl4jbmahp6r4 165 2 necrosis necrosis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 165 3 factor factor NNP work_lbjz23isnfbh5bcl4jbmahp6r4 165 4 α α XX work_lbjz23isnfbh5bcl4jbmahp6r4 165 5 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 165 6 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 165 7 cell cell NN work_lbjz23isnfbh5bcl4jbmahp6r4 165 8 nutrients nutrient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 165 9 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 165 10 e.g. e.g. RB work_lbjz23isnfbh5bcl4jbmahp6r4 166 1 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 166 2 fatty fatty NN work_lbjz23isnfbh5bcl4jbmahp6r4 166 3 acids acid NNS work_lbjz23isnfbh5bcl4jbmahp6r4 166 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 166 5 glucose glucose NN work_lbjz23isnfbh5bcl4jbmahp6r4 166 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 166 7 may may MD work_lbjz23isnfbh5bcl4jbmahp6r4 166 8 regulate regulate VB work_lbjz23isnfbh5bcl4jbmahp6r4 166 9 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 166 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 167 1 Thus thus RB work_lbjz23isnfbh5bcl4jbmahp6r4 167 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 167 3 anakinra anakinra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 167 4 alone alone RB work_lbjz23isnfbh5bcl4jbmahp6r4 167 5 might may MD work_lbjz23isnfbh5bcl4jbmahp6r4 167 6 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 167 7 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 167 8 sufficiently sufficiently RB work_lbjz23isnfbh5bcl4jbmahp6r4 167 9 potent potent JJ work_lbjz23isnfbh5bcl4jbmahp6r4 167 10 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 167 11 inhibit inhibit VB work_lbjz23isnfbh5bcl4jbmahp6r4 167 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 167 13 drive drive NN work_lbjz23isnfbh5bcl4jbmahp6r4 167 14 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 167 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 167 16 other other JJ work_lbjz23isnfbh5bcl4jbmahp6r4 167 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 167 18 unknown unknown JJ work_lbjz23isnfbh5bcl4jbmahp6r4 167 19 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 167 20 factors factor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 167 21 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 167 22 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 167 23 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 167 24 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 167 25 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 167 26 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 168 1 In in IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 2 conclusion conclusion NN work_lbjz23isnfbh5bcl4jbmahp6r4 168 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 168 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 168 5 observed observed JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 6 elevation elevation NN work_lbjz23isnfbh5bcl4jbmahp6r4 168 7 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 8 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 168 9 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 168 10 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 168 11 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 168 12 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 13 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 168 14 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 15 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 16 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 168 17 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 168 18 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 168 19 due due JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 20 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 21 systemic systemic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 22 chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 23 activation activation NN work_lbjz23isnfbh5bcl4jbmahp6r4 168 24 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 25 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 168 26 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 27 system system NN work_lbjz23isnfbh5bcl4jbmahp6r4 168 28 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 168 29 other other JJ work_lbjz23isnfbh5bcl4jbmahp6r4 168 30 factors factor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 168 31 should should MD work_lbjz23isnfbh5bcl4jbmahp6r4 168 32 be be VB work_lbjz23isnfbh5bcl4jbmahp6r4 168 33 investigated investigate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 168 34 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 168 35 elucidate elucidate VB work_lbjz23isnfbh5bcl4jbmahp6r4 168 36 regulators regulator NNS work_lbjz23isnfbh5bcl4jbmahp6r4 168 37 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 168 38 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 168 39 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 168 40 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 168 41 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 168 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 169 1 Declaration declaration NN work_lbjz23isnfbh5bcl4jbmahp6r4 169 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 169 3 interest interest NN work_lbjz23isnfbh5bcl4jbmahp6r4 169 4 MCC MCC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 169 5 received receive VBD work_lbjz23isnfbh5bcl4jbmahp6r4 169 6 speaking speak VBG work_lbjz23isnfbh5bcl4jbmahp6r4 169 7 honoraria honoraria NN work_lbjz23isnfbh5bcl4jbmahp6r4 169 8 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 169 9 Thermo Thermo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 169 10 Fisher Fisher NNP work_lbjz23isnfbh5bcl4jbmahp6r4 169 11 AG AG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 169 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 169 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 169 14 manufacturer manufacturer NN work_lbjz23isnfbh5bcl4jbmahp6r4 169 15 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 169 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 169 17 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 169 18 assay assay NN work_lbjz23isnfbh5bcl4jbmahp6r4 169 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 170 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 170 2 remaining remain VBG work_lbjz23isnfbh5bcl4jbmahp6r4 170 3 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 170 4 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 170 5 nothing nothing NN work_lbjz23isnfbh5bcl4jbmahp6r4 170 6 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 170 7 disclose disclose VB work_lbjz23isnfbh5bcl4jbmahp6r4 170 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 171 1 Funding fund VBG work_lbjz23isnfbh5bcl4jbmahp6r4 171 2 MP MP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 3 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 171 4 MCC MCC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 5 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 171 6 supported support VBN work_lbjz23isnfbh5bcl4jbmahp6r4 171 7 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 171 8 grants grant NNS work_lbjz23isnfbh5bcl4jbmahp6r4 171 9 awarded award VBN work_lbjz23isnfbh5bcl4jbmahp6r4 171 10 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 171 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 171 12 Swiss Swiss NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 13 National National NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 14 Science Science NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 15 Foundation Foundation NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 16 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 171 17 MCC MCC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 18 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 171 19 SNF-162608 SNF-162608 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 20 ; ; : work_lbjz23isnfbh5bcl4jbmahp6r4 171 21 MP MP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 22 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 171 23 SNF-177578 SNF-177578 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 171 24 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 171 25 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 172 1 MCC MCC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 172 2 received receive VBD work_lbjz23isnfbh5bcl4jbmahp6r4 172 3 speaking speak VBG work_lbjz23isnfbh5bcl4jbmahp6r4 172 4 honoraria honoraria NN work_lbjz23isnfbh5bcl4jbmahp6r4 172 5 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 172 6 Thermo Thermo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 172 7 Fisher Fisher NNP work_lbjz23isnfbh5bcl4jbmahp6r4 172 8 AG AG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 172 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 172 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 172 11 manufacturer manufacturer NN work_lbjz23isnfbh5bcl4jbmahp6r4 172 12 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 172 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 172 14 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 172 15 assay assay NN work_lbjz23isnfbh5bcl4jbmahp6r4 172 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 173 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 173 2 remaining remain VBG work_lbjz23isnfbh5bcl4jbmahp6r4 173 3 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 173 4 have have VBP work_lbjz23isnfbh5bcl4jbmahp6r4 173 5 nothing nothing NN work_lbjz23isnfbh5bcl4jbmahp6r4 173 6 to to TO work_lbjz23isnfbh5bcl4jbmahp6r4 173 7 disclose disclose VB work_lbjz23isnfbh5bcl4jbmahp6r4 173 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 174 1 Financial financial JJ work_lbjz23isnfbh5bcl4jbmahp6r4 174 2 support support NN work_lbjz23isnfbh5bcl4jbmahp6r4 174 3 MP MP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 4 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 174 5 MCC MCC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 6 are be VBP work_lbjz23isnfbh5bcl4jbmahp6r4 174 7 supported support VBN work_lbjz23isnfbh5bcl4jbmahp6r4 174 8 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 174 9 grants grant NNS work_lbjz23isnfbh5bcl4jbmahp6r4 174 10 awarded award VBN work_lbjz23isnfbh5bcl4jbmahp6r4 174 11 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 174 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 174 13 Swiss Swiss NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 14 National National NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 15 Science Science NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 16 Foundation Foundation NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 17 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 174 18 MCC MCC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 19 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 174 20 SNF-162608 SNF-162608 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 21 ; ; : work_lbjz23isnfbh5bcl4jbmahp6r4 174 22 MP MP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 23 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 174 24 SNF-177578 SNF-177578 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 174 25 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 174 26 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 175 1 Acknowledgements acknowledgement NNS work_lbjz23isnfbh5bcl4jbmahp6r4 175 2 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 3 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 175 4 thank thank VBP work_lbjz23isnfbh5bcl4jbmahp6r4 175 5 all all DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 6 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 175 7 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 175 8 their -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 175 9 participation participation NN work_lbjz23isnfbh5bcl4jbmahp6r4 175 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 175 11 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 12 staff staff NN work_lbjz23isnfbh5bcl4jbmahp6r4 175 13 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 175 14 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 15 laboratory laboratory NN work_lbjz23isnfbh5bcl4jbmahp6r4 175 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 175 17 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 18 Department Department NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 19 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 175 20 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 175 22 Diabetology Diabetology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 23 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 175 24 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 25 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 175 26 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 27 University University NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 28 Hospital Hospital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 29 Basel Basel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 30 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 175 31 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 175 32 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 175 33 Kantonsspital Kantonsspital NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 34 Aarau Aarau NNP work_lbjz23isnfbh5bcl4jbmahp6r4 175 35 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 176 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 176 2 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 176 3 extend extend VBP work_lbjz23isnfbh5bcl4jbmahp6r4 176 4 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 176 5 special special JJ work_lbjz23isnfbh5bcl4jbmahp6r4 176 6 thanks thank NNS work_lbjz23isnfbh5bcl4jbmahp6r4 176 7 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 176 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 176 9 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 176 10 nurses nurse NNS work_lbjz23isnfbh5bcl4jbmahp6r4 176 11 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 176 12 their -PRON- PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 176 13 most most RBS work_lbjz23isnfbh5bcl4jbmahp6r4 176 14 helpful helpful JJ work_lbjz23isnfbh5bcl4jbmahp6r4 176 15 support support NN work_lbjz23isnfbh5bcl4jbmahp6r4 176 16 during during IN work_lbjz23isnfbh5bcl4jbmahp6r4 176 17 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 176 18 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 176 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 177 1 References reference NNS work_lbjz23isnfbh5bcl4jbmahp6r4 177 2 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 177 3 Eckel eckel NN work_lbjz23isnfbh5bcl4jbmahp6r4 177 4   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 177 5 RH RH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 177 6 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 177 7 Grundy Grundy NNP work_lbjz23isnfbh5bcl4jbmahp6r4 177 8   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 177 9 SM SM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 177 10 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 177 11 Zimmet Zimmet NNP work_lbjz23isnfbh5bcl4jbmahp6r4 177 12   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 177 13 PZ PZ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 177 14 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 178 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 178 2 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 178 3 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 178 4 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 179 1 Lancet Lancet NNP work_lbjz23isnfbh5bcl4jbmahp6r4 179 2 2005 2005 CD work_lbjz23isnfbh5bcl4jbmahp6r4 179 3 365 365 CD work_lbjz23isnfbh5bcl4jbmahp6r4 179 4 1415–1428 1415–1428 CD work_lbjz23isnfbh5bcl4jbmahp6r4 179 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 180 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 180 2 https://doi.org/10.1016/S0140- https://doi.org/10.1016/S0140- NNP work_lbjz23isnfbh5bcl4jbmahp6r4 180 3 6736(05)66378 6736(05)66378 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 180 4 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 180 5 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 180 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 180 7 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 180 8 Melander melander NN work_lbjz23isnfbh5bcl4jbmahp6r4 180 9   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 180 10 O. O. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 180 11 Vasopressin Vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 180 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 180 13 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 180 14 regulator regulator NN work_lbjz23isnfbh5bcl4jbmahp6r4 180 15 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 180 16 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 180 17 predictor predictor NN work_lbjz23isnfbh5bcl4jbmahp6r4 180 18 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 180 19 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 180 20 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 180 21 cardiometabolic cardiometabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 180 22 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 180 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 181 1 Annals annal NNS work_lbjz23isnfbh5bcl4jbmahp6r4 181 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 181 3 Nutrition Nutrition NNP work_lbjz23isnfbh5bcl4jbmahp6r4 181 4 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 181 5 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 181 6 2016 2016 CD work_lbjz23isnfbh5bcl4jbmahp6r4 181 7 68 68 CD work_lbjz23isnfbh5bcl4jbmahp6r4 181 8 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 181 9 Supplement Supplement NNP work_lbjz23isnfbh5bcl4jbmahp6r4 181 10 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 181 11 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 181 12 24–28 24–28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 181 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 182 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 182 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 182 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 183 1 org/10.1159/000446201 org/10.1159/000446201 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 183 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 183 3 3 3 CD work_lbjz23isnfbh5bcl4jbmahp6r4 183 4 Fenske Fenske NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 5   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 6 WK WK NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 7 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 8 Schnyder schnyder NN work_lbjz23isnfbh5bcl4jbmahp6r4 183 9   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 10 I -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 183 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 12 Koch Koch NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 14 G G NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 15 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 16 Walti Walti NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 17   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 18 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 20 Pfister Pfister NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 21   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 22 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 23 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 24 Kopp Kopp NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 25   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 26 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 27 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 28 Fassnacht Fassnacht NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 29   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 30 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 183 32 Strauss Strauss NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 33   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 34 K K NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 35 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 183 36 Christ Christ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 37 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 183 38 Crain Crain NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 39   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 183 40 M. M. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 41 Release Release NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 42 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 183 43 decay decay VB work_lbjz23isnfbh5bcl4jbmahp6r4 183 44 kinetics kinetic NNS work_lbjz23isnfbh5bcl4jbmahp6r4 183 45 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 183 46 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 47 vs vs IN work_lbjz23isnfbh5bcl4jbmahp6r4 183 48 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 183 49 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 183 50 response response NN work_lbjz23isnfbh5bcl4jbmahp6r4 183 51 to to IN work_lbjz23isnfbh5bcl4jbmahp6r4 183 52 osmotic osmotic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 183 53 alterations alteration NNS work_lbjz23isnfbh5bcl4jbmahp6r4 183 54 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 183 55 healthy healthy JJ work_lbjz23isnfbh5bcl4jbmahp6r4 183 56 volunteers volunteer NNS work_lbjz23isnfbh5bcl4jbmahp6r4 183 57 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 184 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 184 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 184 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 184 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 184 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 184 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 184 7 2018 2018 CD work_lbjz23isnfbh5bcl4jbmahp6r4 184 8 103 103 CD work_lbjz23isnfbh5bcl4jbmahp6r4 184 9 505–513 505–513 CD work_lbjz23isnfbh5bcl4jbmahp6r4 184 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 185 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 185 2 https://doi.org/10.1210/jc.2017-01891 https://doi.org/10.1210/jc.2017-01891 NN work_lbjz23isnfbh5bcl4jbmahp6r4 185 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 185 4 4 4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 185 5 Enhörning enhörne VBG work_lbjz23isnfbh5bcl4jbmahp6r4 185 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 7 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 9 Wang Wang NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 11 TJ TJ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 13 Nilsson Nilsson NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 15 PM PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 17 Almgren Almgren NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 19 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 21 Hedblad Hedblad NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 23 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 25 Berglund Berglund NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 27 G G NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 29 Struck Struck NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 31 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 33 Morgenthaler Morgenthaler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 34   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 35 NG NG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 36 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 37 Bergmann Bergmann NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 38   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 39 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 40 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 41 Lindholm Lindholm NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 42   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 43 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 185 44 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 185 45 et et NN work_lbjz23isnfbh5bcl4jbmahp6r4 185 46   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 185 47 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 185 48 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 186 1 Plasma Plasma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 186 2 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 186 3 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 186 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 186 5 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 186 6 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 186 7 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 186 8 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 186 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 187 1 Circulation circulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 187 2 2010 2010 CD work_lbjz23isnfbh5bcl4jbmahp6r4 187 3 121 121 CD work_lbjz23isnfbh5bcl4jbmahp6r4 187 4 2102–2108 2102–2108 CD work_lbjz23isnfbh5bcl4jbmahp6r4 187 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 188 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 188 2 https://doi.org/10.1161/ https://doi.org/10.1161/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 3 CIRCULATIONAHA.109.909663 CIRCULATIONAHA.109.909663 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 188 5 5 5 CD work_lbjz23isnfbh5bcl4jbmahp6r4 188 6 Abbasi Abbasi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 8 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 188 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 10 Corpeleijn Corpeleijn NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 12 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 188 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 14 Meijer Meijer NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 16 E E NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 18 Postmus Postmus NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 20 D D NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 22 Gansevoort gansevoort NN work_lbjz23isnfbh5bcl4jbmahp6r4 188 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 24 RT RT NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 26 Gans Gans NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 27   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 28 ROB ROB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 30 Struck Struck NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 31   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 32 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 34 Hillege Hillege NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 35   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 36 HL HL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 37 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 38 Stolk Stolk NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 39   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 40 RP RP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 41 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 42 Navis Navis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 43   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 44 G g NN work_lbjz23isnfbh5bcl4jbmahp6r4 188 45 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 188 46 et et NN work_lbjz23isnfbh5bcl4jbmahp6r4 188 47   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 188 48 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 188 49 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 189 1 Sex sex NN work_lbjz23isnfbh5bcl4jbmahp6r4 189 2 differences difference NNS work_lbjz23isnfbh5bcl4jbmahp6r4 189 3 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 189 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 189 5 association association NN work_lbjz23isnfbh5bcl4jbmahp6r4 189 6 between between IN work_lbjz23isnfbh5bcl4jbmahp6r4 189 7 plasma plasma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 8 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 189 10 incident incident NN work_lbjz23isnfbh5bcl4jbmahp6r4 189 11 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 189 12 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 189 13 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 189 14 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 189 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 189 16 Prevention Prevention NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 17 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 189 18 Renal renal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 189 19 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 189 20 Vascular Vascular NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 21 Endstage Endstage NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 22 Disease Disease NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 23 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 189 24 PREVEND PREVEND NNP work_lbjz23isnfbh5bcl4jbmahp6r4 189 25 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 189 26 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 189 27 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 190 1 Diabetologia Diabetologia NNP work_lbjz23isnfbh5bcl4jbmahp6r4 190 2 2012 2012 CD work_lbjz23isnfbh5bcl4jbmahp6r4 190 3 55 55 CD work_lbjz23isnfbh5bcl4jbmahp6r4 190 4 1963–1970 1963–1970 CD work_lbjz23isnfbh5bcl4jbmahp6r4 190 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 191 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 191 2 https:// https:// NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 3 doi.org/10.1007/s00125-012-2545-x doi.org/10.1007/s00125-012-2545-x NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 191 5 6 6 CD work_lbjz23isnfbh5bcl4jbmahp6r4 191 6 Enhörning enhörne VBG work_lbjz23isnfbh5bcl4jbmahp6r4 191 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 8 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 10 Bankir Bankir NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 12 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 14 Bouby Bouby NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 16 N N NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 18 Struck Struck NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 20 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 22 Hedblad Hedblad NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 24 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 26 Persson Persson NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 27   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 28 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 30 Morgenthaler Morgenthaler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 31   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 32 NG NG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 34 Nilsson Nilsson NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 35   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 36 PM PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 37 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 191 38 Melander Melander NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 39   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 191 40 O. O. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 41 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 42 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 43 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 191 44 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 191 45 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 191 46 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 191 47 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 48 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 191 49 abdominal abdominal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 191 50 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 191 51 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 191 52 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 191 53 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 191 54 microalbuminuria microalbuminuria NN work_lbjz23isnfbh5bcl4jbmahp6r4 191 55 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 191 56 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 191 57 prospective prospective JJ work_lbjz23isnfbh5bcl4jbmahp6r4 191 58 Malmö Malmö NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 59 Diet Diet NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 60 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 191 61 Cancer Cancer NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 62 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 191 63 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 191 64 cohort cohort NN work_lbjz23isnfbh5bcl4jbmahp6r4 191 65 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 192 1 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 192 2 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 192 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 192 4 Obesity Obesity NNP work_lbjz23isnfbh5bcl4jbmahp6r4 192 5 2013 2013 CD work_lbjz23isnfbh5bcl4jbmahp6r4 192 6 37 37 CD work_lbjz23isnfbh5bcl4jbmahp6r4 192 7 598–603 598–603 CD work_lbjz23isnfbh5bcl4jbmahp6r4 192 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 193 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 193 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 193 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 194 1 org/10.1038 org/10.1038 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 2 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 194 3 ijo.2012.88 ijo.2012.88 CD work_lbjz23isnfbh5bcl4jbmahp6r4 194 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 194 5 7 7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 194 6 Asferg Asferg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 194 8 CL CL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 194 10 Andersen Andersen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 194 12 UB UB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 194 14 Linneberg Linneberg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 194 16 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 194 18 Goetze Goetze NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 194 20 JP JP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 21 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 194 22 Jeppesen Jeppesen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 194 24 JL JL NNP work_lbjz23isnfbh5bcl4jbmahp6r4 194 25 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 195 1 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 195 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 195 3 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 195 4 surrogate surrogate JJ work_lbjz23isnfbh5bcl4jbmahp6r4 195 5 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 195 6 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 195 7 arginine arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 195 8 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 195 9 secretion secretion NNP work_lbjz23isnfbh5bcl4jbmahp6r4 195 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 195 11 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 195 12 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 195 13 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 195 14 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 195 15 glucose glucose NN work_lbjz23isnfbh5bcl4jbmahp6r4 195 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 195 17 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 195 18 concentrations concentration NNS work_lbjz23isnfbh5bcl4jbmahp6r4 195 19 but but CC work_lbjz23isnfbh5bcl4jbmahp6r4 195 20 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 195 21 higher high JJR work_lbjz23isnfbh5bcl4jbmahp6r4 195 22 blood blood NN work_lbjz23isnfbh5bcl4jbmahp6r4 195 23 pressure pressure NN work_lbjz23isnfbh5bcl4jbmahp6r4 195 24 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 195 25 obese obese JJ work_lbjz23isnfbh5bcl4jbmahp6r4 195 26 men man NNS work_lbjz23isnfbh5bcl4jbmahp6r4 195 27 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 196 1 Diabetic Diabetic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 196 2 Medicine Medicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 196 3 2014 2014 CD work_lbjz23isnfbh5bcl4jbmahp6r4 196 4 31 31 CD work_lbjz23isnfbh5bcl4jbmahp6r4 196 5 728–732 728–732 CD work_lbjz23isnfbh5bcl4jbmahp6r4 196 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 197 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 197 2 https://doi.org/10.1111/dme.12411 https://doi.org/10.1111/dme.12411 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 197 4 8 8 CD work_lbjz23isnfbh5bcl4jbmahp6r4 197 5 Then then RB work_lbjz23isnfbh5bcl4jbmahp6r4 197 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 7 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 9 Kowall Kowall NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 11 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 13 Lechner Lechner NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 15 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 17 Meisinger Meisinger NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 19 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 21 Heier Heier NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 23 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 25 Koenig Koenig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 27 W W NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 29 Peters Peters NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 31 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 197 33 Rathmann Rathmann NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 34   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 35 W W NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 36 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 197 37 Seissler Seissler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 197 38   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 197 39 J. J. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 198 1 Plasma Plasma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 198 2 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 198 3 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 198 4 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 198 5 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 198 6 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 198 7 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 198 8 diabetes diabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 198 9 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 198 10 men man NNS work_lbjz23isnfbh5bcl4jbmahp6r4 198 11 but but CC work_lbjz23isnfbh5bcl4jbmahp6r4 198 12 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 198 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 198 14 women woman NNS work_lbjz23isnfbh5bcl4jbmahp6r4 198 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 198 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 198 17 population- population- NN work_lbjz23isnfbh5bcl4jbmahp6r4 198 18 based base VBN work_lbjz23isnfbh5bcl4jbmahp6r4 198 19 KORA KORA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 198 20 F4 F4 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 198 21 study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 198 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 199 1 Acta Acta NNP work_lbjz23isnfbh5bcl4jbmahp6r4 199 2 Diabetologica Diabetologica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 199 3 2015 2015 CD work_lbjz23isnfbh5bcl4jbmahp6r4 199 4 52 52 CD work_lbjz23isnfbh5bcl4jbmahp6r4 199 5 103–112 103–112 CD work_lbjz23isnfbh5bcl4jbmahp6r4 199 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 200 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 200 2 https:// https:// NN work_lbjz23isnfbh5bcl4jbmahp6r4 200 3 doi.org/10.1007/s00592-014-0609-8 doi.org/10.1007/s00592-014-0609-8 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 200 5 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 200 6 Roussel Roussel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 8 R R NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 10 Boustany Boustany NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 12 R R NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 13 El El NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 15 Bouby Bouby NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 16   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 17 N N NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 19 Potier Potier NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 20   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 21 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 22 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 23 Fumeron Fumeron NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 24   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 25 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 26 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 27 Mohammedi Mohammedi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 28   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 29 K K NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 31 Balkau Balkau NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 32   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 33 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 200 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 35 Tichet Tichet NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 36   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 37 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 39 Bankir Bankir NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 41 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 42 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 43 Marre Marre NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 44   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 45 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 46 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 200 47 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 48   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 200 49 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 200 50 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 201 1 Plasma Plasma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 201 2 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 201 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 201 4 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 201 5 gene gene NN work_lbjz23isnfbh5bcl4jbmahp6r4 201 6 variants variant NNS work_lbjz23isnfbh5bcl4jbmahp6r4 201 7 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 201 8 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 201 9 incidence incidence NN work_lbjz23isnfbh5bcl4jbmahp6r4 201 10 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 201 11 Type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 201 12 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 201 13 diabetes diabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 201 14 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 201 15 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 201 16 cohort cohort NN work_lbjz23isnfbh5bcl4jbmahp6r4 201 17 From from IN work_lbjz23isnfbh5bcl4jbmahp6r4 201 18 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 201 19 community community NN work_lbjz23isnfbh5bcl4jbmahp6r4 201 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 202 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 202 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 202 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 202 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 202 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 202 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 202 7 2016 2016 CD work_lbjz23isnfbh5bcl4jbmahp6r4 202 8 101 101 CD work_lbjz23isnfbh5bcl4jbmahp6r4 202 9 2432–2439 2432–2439 CD work_lbjz23isnfbh5bcl4jbmahp6r4 202 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 203 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 203 2 https://doi.org/10.1210/jc.2016- https://doi.org/10.1210/jc.2016- NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 3 1113 1113 CD work_lbjz23isnfbh5bcl4jbmahp6r4 203 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 203 5 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 203 6 Vintilă Vintilă NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 8 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 10 Gheorghiu Gheorghiu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 12 ML ML NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 14 Caragheorgheopol Caragheorgheopol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 16 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 18 Baculescu Baculescu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 20 N N NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 22 Lichiardopol Lichiardopol NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 24 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 26 Badiu Badiu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 27   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 28 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 30 Coculescu Coculescu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 31   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 32 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 203 34 Grigorescu Grigorescu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 35   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 36 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 37 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 203 38 Poiană Poiană NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 39   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 203 40 C. C. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 41 Increased Increased NNP work_lbjz23isnfbh5bcl4jbmahp6r4 203 42 copeptin copeptin JJ work_lbjz23isnfbh5bcl4jbmahp6r4 203 43 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 203 44 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 203 45 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 203 46 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 203 47 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 203 48 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 203 49 Romanian romanian JJ work_lbjz23isnfbh5bcl4jbmahp6r4 203 50 population population NN work_lbjz23isnfbh5bcl4jbmahp6r4 203 51 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 204 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 204 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 204 3 Medicine Medicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 204 4 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 204 5 Life Life NNP work_lbjz23isnfbh5bcl4jbmahp6r4 204 6 2016 2016 CD work_lbjz23isnfbh5bcl4jbmahp6r4 204 7 9 9 CD work_lbjz23isnfbh5bcl4jbmahp6r4 204 8 353–357 353–357 CD work_lbjz23isnfbh5bcl4jbmahp6r4 204 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 205 1 11 11 CD work_lbjz23isnfbh5bcl4jbmahp6r4 205 2 Riphagen Riphagen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 3   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 4 IJ IJ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 6 Boertien Boertien NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 8 WE WE NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 10 Alkhalaf Alkhalaf NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 12 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 14 Kleefstra Kleefstra NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 16 N N NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 18 Gansevoort Gansevoort NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 20 RT RT NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 22 Groenier Groenier NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 24 KH KH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 26 van van NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 27 Hateren Hateren NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 28   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 29 KJJ KJJ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 31 Struck Struck NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 32   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 33 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 35 Navis Navis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 36   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 37 G g NN work_lbjz23isnfbh5bcl4jbmahp6r4 205 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 39 Bilo Bilo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 41 HJG HJG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 42 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 205 43 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 44   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 205 45 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 205 46 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 206 1 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 206 2 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 206 3 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 206 4 surrogate surrogate JJ work_lbjz23isnfbh5bcl4jbmahp6r4 206 5 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 206 6 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 206 7 arginine arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 206 8 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 206 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 206 10 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 206 11 associated associate VBN work_lbjz23isnfbh5bcl4jbmahp6r4 206 12 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 206 13 cardiovascular cardiovascular JJ work_lbjz23isnfbh5bcl4jbmahp6r4 206 14 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 206 15 all all DT work_lbjz23isnfbh5bcl4jbmahp6r4 206 16 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 206 17 cause cause VB work_lbjz23isnfbh5bcl4jbmahp6r4 206 18 mortality mortality NN work_lbjz23isnfbh5bcl4jbmahp6r4 206 19 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 206 20 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 206 21 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 206 22 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 206 23 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 206 24 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 206 25 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 206 26 ZODIAC-31 ZODIAC-31 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 206 27 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 206 28 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 207 1 Diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 207 2 Care care NN work_lbjz23isnfbh5bcl4jbmahp6r4 207 3 2013 2013 CD work_lbjz23isnfbh5bcl4jbmahp6r4 207 4 36 36 CD work_lbjz23isnfbh5bcl4jbmahp6r4 207 5 3201–3207 3201–3207 CD work_lbjz23isnfbh5bcl4jbmahp6r4 207 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 208 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 208 2 https:// https:// NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 3 doi.org/10.2337/dc12-2165 doi.org/10.2337/dc12-2165 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 208 5 12 12 CD work_lbjz23isnfbh5bcl4jbmahp6r4 208 6 Zellweger Zellweger NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 8 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 10 Wildi Wildi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 12 K K NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 14 Twerenbold Twerenbold NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 16 R R NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 18 Reichlin Reichlin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 20 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 22 Naduvilekoot Naduvilekoot NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 24 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 26 Neuhaus Neuhaus NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 27   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 28 JD JD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 30 Balmelli Balmelli NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 31   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 32 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 34 Gabutti Gabutti NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 35   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 36 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 37 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 38 Afify Afify NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 39   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 40 AAl AAl NNS work_lbjz23isnfbh5bcl4jbmahp6r4 208 41 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 42 Ballarino Ballarino NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 43   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 44 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 45 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 208 46 et et NN work_lbjz23isnfbh5bcl4jbmahp6r4 208 47   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 208 48 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 208 49 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 209 1 Use use NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 3 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 4 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 209 5 high high JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 6 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 209 7 sensitive sensitive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 8 cardiac cardiac NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 9 troponin troponin NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 10 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 11 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 12 diagnosis diagnosis NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 13 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 209 14 prognosis prognosis NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 15 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 16 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 209 17 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 18 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 19 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 20 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 209 21 suspected suspect VBD work_lbjz23isnfbh5bcl4jbmahp6r4 209 22 acute acute JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 23 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 209 24 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 25 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 209 26 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 209 27 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 28 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 209 29 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 30 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 31 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 32 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 209 33 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 34 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 209 35 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 36 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 37 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 209 38 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 39 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 209 40 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 209 41 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 209 42 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 209 43 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 44 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 45 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 46 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 209 47 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 48 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 49 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 50 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 209 51 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 52 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 209 53 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 54 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 209 55 https://doi.org/10.1016/S0140-6736(05)66378-7 https://doi.org/10.1016/S0140-6736(05)66378-7 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 56 https://doi.org/10.1016/S0140-6736(05)66378-7 https://doi.org/10.1016/S0140-6736(05)66378-7 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 57 https://doi.org/10.1159/000446201 https://doi.org/10.1159/000446201 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 58 https://doi.org/10.1159/000446201 https://doi.org/10.1159/000446201 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 59 https://doi.org/10.1210/jc.2017-01891 https://doi.org/10.1210/jc.2017-01891 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 209 60 https://doi.org/10.1161/CIRCULATIONAHA.109.909663 https://doi.org/10.1161/CIRCULATIONAHA.109.909663 NNS work_lbjz23isnfbh5bcl4jbmahp6r4 209 61 https://doi.org/10.1161/CIRCULATIONAHA.109.909663 https://doi.org/10.1161/CIRCULATIONAHA.109.909663 -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 209 62 https://doi.org/10.1007/s00125-012-2545-x https://doi.org/10.1007/s00125-012-2545-x NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 63 https://doi.org/10.1007/s00125-012-2545-x https://doi.org/10.1007/s00125-012-2545-x NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 64 https://doi.org/10.1038/ijo.2012.88 https://doi.org/10.1038/ijo.2012.88 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 65 https://doi.org/10.1038/ijo.2012.88 https://doi.org/10.1038/ijo.2012.88 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 66 https://doi.org/10.1111/dme.12411 https://doi.org/10.1111/dme.12411 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 67 https://doi.org/10.1007/s00592-014-0609-8 https://doi.org/10.1007/s00592-014-0609-8 VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 209 68 https://doi.org/10.1007/s00592-014-0609-8 https://doi.org/10.1007/s00592-014-0609-8 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 69 https://doi.org/10.1210/jc.2016-1113 https://doi.org/10.1210/jc.2016-1113 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 70 https://doi.org/10.1210/jc.2016-1113 https://doi.org/10.1210/jc.2016-1113 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 71 https://doi.org/10.2337/dc12-2165 https://doi.org/10.2337/dc12-2165 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 72 https://doi.org/10.2337/dc12-2165 https://doi.org/10.2337/dc12-2165 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 73 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 74 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 75 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 76 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 77 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 78 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 79 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 80   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 209 81 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 209 82 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 210 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 210 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 210 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 210 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 210 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 210 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 210 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 210 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 210 9 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 210 10 722 722 CD work_lbjz23isnfbh5bcl4jbmahp6r4 210 11 PB PB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 210 12 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 210 13 XX XX NNP work_lbjz23isnfbh5bcl4jbmahp6r4 210 14 9:7 9:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 210 15 myocardial myocardial JJ work_lbjz23isnfbh5bcl4jbmahp6r4 210 16 infarction infarction NN work_lbjz23isnfbh5bcl4jbmahp6r4 210 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 211 1 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 211 2 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 211 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 211 4 Cardiology Cardiology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 211 5 2015 2015 CD work_lbjz23isnfbh5bcl4jbmahp6r4 211 6 190 190 CD work_lbjz23isnfbh5bcl4jbmahp6r4 211 7 190–197 190–197 CD work_lbjz23isnfbh5bcl4jbmahp6r4 211 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 212 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 212 2 https://doi.org/10.1016/j.ijcard.2015.04.134 https://doi.org/10.1016/j.ijcard.2015.04.134 UH work_lbjz23isnfbh5bcl4jbmahp6r4 212 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 212 4 13 13 CD work_lbjz23isnfbh5bcl4jbmahp6r4 212 5 Enhörning enhörne VBG work_lbjz23isnfbh5bcl4jbmahp6r4 212 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 212 7 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 212 9 Hedblad Hedblad NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 212 11 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 212 13 Nilsson Nilsson NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 212 15 PM pm NN work_lbjz23isnfbh5bcl4jbmahp6r4 212 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 212 17 Engström Engström NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 212 19 G G NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 20 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 212 21 Melander Melander NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 212 23 O. O. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 24 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 212 25 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 212 26 an an DT work_lbjz23isnfbh5bcl4jbmahp6r4 212 27 independent independent JJ work_lbjz23isnfbh5bcl4jbmahp6r4 212 28 predictor predictor NN work_lbjz23isnfbh5bcl4jbmahp6r4 212 29 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 212 30 diabetic diabetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 212 31 heart heart NN work_lbjz23isnfbh5bcl4jbmahp6r4 212 32 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 212 33 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 212 34 death death NN work_lbjz23isnfbh5bcl4jbmahp6r4 212 35 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 213 1 American American NNP work_lbjz23isnfbh5bcl4jbmahp6r4 213 2 Heart Heart NNP work_lbjz23isnfbh5bcl4jbmahp6r4 213 3 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 213 4 2015 2015 CD work_lbjz23isnfbh5bcl4jbmahp6r4 213 5 169 169 CD work_lbjz23isnfbh5bcl4jbmahp6r4 213 6 549–556.e1 549–556.e1 NNS work_lbjz23isnfbh5bcl4jbmahp6r4 213 7 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 214 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 214 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 214 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 215 1 org/10.1016 org/10.1016 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 2 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 215 3 J.AHJ.2014.11.020 j.ahj.2014.11.020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 215 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 215 5 14 14 CD work_lbjz23isnfbh5bcl4jbmahp6r4 215 6 Gallo Gallo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 7 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 215 8 Payet payet NN work_lbjz23isnfbh5bcl4jbmahp6r4 215 9   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 215 10 N N NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 11 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 215 12 Guillon Guillon NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 215 14 G. G. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 15 Regulation Regulation NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 215 17 adrenocortical adrenocortical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 215 18 function function NN work_lbjz23isnfbh5bcl4jbmahp6r4 215 19 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 215 20 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 215 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 216 1 Hormone Hormone NNP work_lbjz23isnfbh5bcl4jbmahp6r4 216 2 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 216 3 Metabolic Metabolic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 216 4 Research Research NNP work_lbjz23isnfbh5bcl4jbmahp6r4 216 5 1998 1998 CD work_lbjz23isnfbh5bcl4jbmahp6r4 216 6 30 30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 216 7 360–367 360–367 CD work_lbjz23isnfbh5bcl4jbmahp6r4 216 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 217 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 217 2 https://doi.org/10.1055/s-2007-978899 https://doi.org/10.1055/s-2007-978899 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 217 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 217 4 15 15 CD work_lbjz23isnfbh5bcl4jbmahp6r4 217 5 Scott Scott NNP work_lbjz23isnfbh5bcl4jbmahp6r4 217 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 217 7 LV LV NNP work_lbjz23isnfbh5bcl4jbmahp6r4 217 8 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 217 9 Dinan Dinan NNP work_lbjz23isnfbh5bcl4jbmahp6r4 217 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 217 11 TG TG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 217 12 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 218 1 Vasopressin Vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 218 2 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 218 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 218 4 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 218 5 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 218 6 hypothalamic hypothalamic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 218 7 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 218 8 pituitary pituitary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 218 9 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 218 10 adrenal adrenal NN work_lbjz23isnfbh5bcl4jbmahp6r4 218 11 axis axis NN work_lbjz23isnfbh5bcl4jbmahp6r4 218 12 function function NN work_lbjz23isnfbh5bcl4jbmahp6r4 218 13 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 218 14 implications implication NNS work_lbjz23isnfbh5bcl4jbmahp6r4 218 15 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 218 16 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 218 17 pathophysiology pathophysiology NN work_lbjz23isnfbh5bcl4jbmahp6r4 218 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 218 19 depression depression NN work_lbjz23isnfbh5bcl4jbmahp6r4 218 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 219 1 Life Life NNP work_lbjz23isnfbh5bcl4jbmahp6r4 219 2 Sciences Sciences NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 219 3 1998 1998 CD work_lbjz23isnfbh5bcl4jbmahp6r4 219 4 62 62 CD work_lbjz23isnfbh5bcl4jbmahp6r4 219 5 1985–1998 1985–1998 CD work_lbjz23isnfbh5bcl4jbmahp6r4 219 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 220 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 220 2 https://doi.org/10.1016/s0024-3205(98)00027-7 https://doi.org/10.1016/s0024-3205(98)00027-7 NN work_lbjz23isnfbh5bcl4jbmahp6r4 220 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 220 4 16 16 CD work_lbjz23isnfbh5bcl4jbmahp6r4 220 5 Grazzini grazzini NN work_lbjz23isnfbh5bcl4jbmahp6r4 220 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 7 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 220 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 9 Breton Breton NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 11 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 13 Derick Derick NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 15 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 17 Andres Andres NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 19 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 21 Raufaste raufaste NN work_lbjz23isnfbh5bcl4jbmahp6r4 220 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 23 D d NN work_lbjz23isnfbh5bcl4jbmahp6r4 220 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 25 Rickwaert Rickwaert NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 27 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 29 Boccara Boccara NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 31 G G NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 33 Colson Colson NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 34   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 35 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 36 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 37 Guérineau Guérineau NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 38   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 39 NC NC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 40 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 41 Serradeil Serradeil NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 42 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 220 43 Le Le NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 44 Gal Gal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 45   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 46 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 47 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 220 48 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 49   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 220 50 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 220 51 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 221 1 Vasopressin Vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 221 2 receptors receptor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 221 3 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 221 4 human human JJ work_lbjz23isnfbh5bcl4jbmahp6r4 221 5 adrenal adrenal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 221 6 medulla medulla NNP work_lbjz23isnfbh5bcl4jbmahp6r4 221 7 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 221 8 pheochromocytoma pheochromocytoma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 221 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 222 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 222 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 222 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 222 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 222 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 222 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 222 7 1999 1999 CD work_lbjz23isnfbh5bcl4jbmahp6r4 222 8 84 84 CD work_lbjz23isnfbh5bcl4jbmahp6r4 222 9 2195–2203 2195–2203 CD work_lbjz23isnfbh5bcl4jbmahp6r4 222 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 223 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 223 2 https://doi.org/10.1210/jcem.84.6.5775 https://doi.org/10.1210/jcem.84.6.5775 PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 223 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 223 4 17 17 CD work_lbjz23isnfbh5bcl4jbmahp6r4 223 5 Hems Hems NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 223 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 223 7 DA DA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 223 8 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 223 9 Whitton Whitton NNP work_lbjz23isnfbh5bcl4jbmahp6r4 223 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 223 11 PD PD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 223 12 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 224 1 Stimulation stimulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 224 2 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 224 3 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 224 4 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 224 5 glycogen glycogen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 224 6 breakdown breakdown NNP work_lbjz23isnfbh5bcl4jbmahp6r4 224 7 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 224 8 gluconeogenesis gluconeogenesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 224 9 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 224 10 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 224 11 perfused perfuse VBN work_lbjz23isnfbh5bcl4jbmahp6r4 224 12 rat rat NN work_lbjz23isnfbh5bcl4jbmahp6r4 224 13 liver liver NN work_lbjz23isnfbh5bcl4jbmahp6r4 224 14 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 225 1 Biochemical Biochemical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 225 2 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 225 3 1973 1973 CD work_lbjz23isnfbh5bcl4jbmahp6r4 225 4 136 136 CD work_lbjz23isnfbh5bcl4jbmahp6r4 225 5 705–709 705–709 CD work_lbjz23isnfbh5bcl4jbmahp6r4 225 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 226 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 226 2 https://doi.org/10.1042/bj1360705 https://doi.org/10.1042/bj1360705 NN work_lbjz23isnfbh5bcl4jbmahp6r4 226 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 226 4 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 226 5 Hiroyama Hiroyama NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 7 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 9 Aoyagi Aoyagi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 11 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 13 Fujiwara Fujiwara NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 15 Y Y NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 17 Birumachi Birumachi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 19 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 21 Shigematsu Shigematsu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 23 Y Y NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 25 Kiwaki Kiwaki NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 27 K K NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 29 Tasaki tasaki NN work_lbjz23isnfbh5bcl4jbmahp6r4 226 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 31 R r NN work_lbjz23isnfbh5bcl4jbmahp6r4 226 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 226 33 Endo Endo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 34   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 35 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 36 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 226 37 Tanoue Tanoue NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 38   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 226 39 A. a. NN work_lbjz23isnfbh5bcl4jbmahp6r4 226 40 Hypermetabolism hypermetabolism NN work_lbjz23isnfbh5bcl4jbmahp6r4 226 41 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 226 42 fat fat NN work_lbjz23isnfbh5bcl4jbmahp6r4 226 43 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 226 44 V1a V1a NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 45 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 46 receptor receptor NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 47 knockout knockout NNP work_lbjz23isnfbh5bcl4jbmahp6r4 226 48 mice mouse NNS work_lbjz23isnfbh5bcl4jbmahp6r4 226 49 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 227 1 Molecular Molecular NNP work_lbjz23isnfbh5bcl4jbmahp6r4 227 2 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 227 3 2007 2007 CD work_lbjz23isnfbh5bcl4jbmahp6r4 227 4 21 21 CD work_lbjz23isnfbh5bcl4jbmahp6r4 227 5 247–258 247–258 CD work_lbjz23isnfbh5bcl4jbmahp6r4 227 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 228 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 228 2 https://doi.org/10.1210/me.2006-0069 https://doi.org/10.1210/me.2006-0069 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 228 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 228 4 19 19 CD work_lbjz23isnfbh5bcl4jbmahp6r4 228 5 Filep Filep NNP work_lbjz23isnfbh5bcl4jbmahp6r4 228 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 228 7 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 228 8 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 228 9 Rosenkranz Rosenkranz NNP work_lbjz23isnfbh5bcl4jbmahp6r4 228 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 228 11 B. B. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 229 1 Mechanism mechanism NN work_lbjz23isnfbh5bcl4jbmahp6r4 229 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 229 3 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 229 4 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 229 5 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 229 6 platelet platelet NN work_lbjz23isnfbh5bcl4jbmahp6r4 229 7 aggregation aggregation NN work_lbjz23isnfbh5bcl4jbmahp6r4 229 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 230 1 Thrombosis Thrombosis NNP work_lbjz23isnfbh5bcl4jbmahp6r4 230 2 Research Research NNP work_lbjz23isnfbh5bcl4jbmahp6r4 230 3 1987 1987 CD work_lbjz23isnfbh5bcl4jbmahp6r4 230 4 45 45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 230 5 7–15 7–15 CD work_lbjz23isnfbh5bcl4jbmahp6r4 230 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 231 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 231 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 231 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 232 1 org/10.1016/0049 org/10.1016/0049 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 2 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 232 3 3848(87)90252 3848(87)90252 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 4 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 232 5 0 0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 232 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 232 7 20 20 CD work_lbjz23isnfbh5bcl4jbmahp6r4 232 8 Maturi Maturi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 9   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 10 MF MF NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 12 Martin Martin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 14 SE SE NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 15 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 16 Markle Markle NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 17   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 18 D D NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 20 Maxwell Maxwell NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 21   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 22 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 23 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 24 Burruss Burruss NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 25   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 26 CR CR NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 27 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 28 Speir Speir NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 29   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 30 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 232 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 32 Greene Greene NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 33   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 34 R R NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 35 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 36 Ro ro NN work_lbjz23isnfbh5bcl4jbmahp6r4 232 37   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 38 YM YM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 39 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 232 40 Vitale Vitale NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 41   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 42 D D NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 43 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 232 44 Green Green NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 45   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 232 46 MV MV NNP work_lbjz23isnfbh5bcl4jbmahp6r4 232 47 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 233 1 Coronary coronary JJ work_lbjz23isnfbh5bcl4jbmahp6r4 233 2 vasoconstriction vasoconstriction NN work_lbjz23isnfbh5bcl4jbmahp6r4 233 3 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 233 4 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 233 5 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 233 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 234 1 Production production NN work_lbjz23isnfbh5bcl4jbmahp6r4 234 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 234 3 myocardial myocardial JJ work_lbjz23isnfbh5bcl4jbmahp6r4 234 4 ischemia ischemia NN work_lbjz23isnfbh5bcl4jbmahp6r4 234 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 234 6 dogs dog NNS work_lbjz23isnfbh5bcl4jbmahp6r4 234 7 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 234 8 constriction constriction NN work_lbjz23isnfbh5bcl4jbmahp6r4 234 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 234 10 nondiseased nondiseased JJ work_lbjz23isnfbh5bcl4jbmahp6r4 234 11 small small JJ work_lbjz23isnfbh5bcl4jbmahp6r4 234 12 vessels vessel NNS work_lbjz23isnfbh5bcl4jbmahp6r4 234 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 235 1 Circulation circulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 235 2 1991 1991 CD work_lbjz23isnfbh5bcl4jbmahp6r4 235 3 83 83 CD work_lbjz23isnfbh5bcl4jbmahp6r4 235 4 2111–2121 2111–2121 CD work_lbjz23isnfbh5bcl4jbmahp6r4 235 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 236 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 236 2 https://doi.org/10.1161/01.cir.83.6.2111 https://doi.org/10.1161/01.cir.83.6.2111 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 236 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 236 4 21 21 CD work_lbjz23isnfbh5bcl4jbmahp6r4 236 5 Enhörning enhörne VBG work_lbjz23isnfbh5bcl4jbmahp6r4 236 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 236 7 S s NN work_lbjz23isnfbh5bcl4jbmahp6r4 236 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 236 9 Struck Struck NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 236 11 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 236 13 Wirfält Wirfält NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 236 15 E E NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 236 17 Hedblad Hedblad NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 236 19 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 236 21 Morgenthaler morgenthaler NN work_lbjz23isnfbh5bcl4jbmahp6r4 236 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 236 23 NG NG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 24 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 236 25 Melander Melander NNP work_lbjz23isnfbh5bcl4jbmahp6r4 236 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 236 27 O. O. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 237 1 Plasma Plasma NNP work_lbjz23isnfbh5bcl4jbmahp6r4 237 2 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 237 3 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 237 4 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 237 5 unifying unifying JJ work_lbjz23isnfbh5bcl4jbmahp6r4 237 6 factor factor NN work_lbjz23isnfbh5bcl4jbmahp6r4 237 7 behind behind IN work_lbjz23isnfbh5bcl4jbmahp6r4 237 8 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 237 9 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 237 10 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 237 11 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 238 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 238 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 238 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 238 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 238 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 238 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 238 7 2011 2011 CD work_lbjz23isnfbh5bcl4jbmahp6r4 238 8 96 96 CD work_lbjz23isnfbh5bcl4jbmahp6r4 238 9 E1065–E1072 e1065–e1072 NN work_lbjz23isnfbh5bcl4jbmahp6r4 238 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 239 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 239 2 https://doi.org/10.1210/jc.2010-2981 https://doi.org/10.1210/jc.2010-2981 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 239 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 239 4 22 22 CD work_lbjz23isnfbh5bcl4jbmahp6r4 239 5 Wannamethee wannamethee NN work_lbjz23isnfbh5bcl4jbmahp6r4 239 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 239 7 SG SG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 239 9 Welsh Welsh NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 239 11 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 239 13 Papacosta Papacosta NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 239 15 O o UH work_lbjz23isnfbh5bcl4jbmahp6r4 239 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 239 17 Lennon lennon NN work_lbjz23isnfbh5bcl4jbmahp6r4 239 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 239 19 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 239 21 Whincup Whincup NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 239 23 PH PH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 24 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 239 25 Sattar Sattar NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 239 27 N. N. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 28 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 239 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 239 30 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 239 31 resistance resistance NN work_lbjz23isnfbh5bcl4jbmahp6r4 239 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 239 33 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 239 34 risk risk NN work_lbjz23isnfbh5bcl4jbmahp6r4 239 35 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 239 36 incident incident NN work_lbjz23isnfbh5bcl4jbmahp6r4 239 37 diabetes diabete NNS work_lbjz23isnfbh5bcl4jbmahp6r4 239 38 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 239 39 older old JJR work_lbjz23isnfbh5bcl4jbmahp6r4 239 40 men man NNS work_lbjz23isnfbh5bcl4jbmahp6r4 239 41 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 240 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 240 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 240 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 240 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 240 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 240 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 240 7 2015 2015 CD work_lbjz23isnfbh5bcl4jbmahp6r4 240 8 100 100 CD work_lbjz23isnfbh5bcl4jbmahp6r4 240 9 3332–3339 3332–3339 CD work_lbjz23isnfbh5bcl4jbmahp6r4 240 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 241 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 241 2 https://doi.org/10.1210/JC.2015-2362 https://doi.org/10.1210/JC.2015-2362 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 241 4 23 23 CD work_lbjz23isnfbh5bcl4jbmahp6r4 241 5 Barchetta Barchetta NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 7 I -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 241 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 9 Enhörning enhörne VBG work_lbjz23isnfbh5bcl4jbmahp6r4 241 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 11 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 13 Cimini Cimini NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 15 FA FA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 17 Capoccia Capoccia NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 19 D D NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 21 Chiappetta Chiappetta NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 23 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 25 Cristofano Cristofano NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 27 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 28 Di Di NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 30 Silecchia Silecchia NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 31   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 32 G G NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 33 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 34 Leonetti Leonetti NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 35   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 36 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 37 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 241 38 Melander Melander NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 39   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 40 O O NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 41 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 241 42 Cavallo Cavallo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 43   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 241 44 MG MG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 241 45 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 241 46 Elevated elevated JJ work_lbjz23isnfbh5bcl4jbmahp6r4 241 47 plasma plasma NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 48 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 49 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 241 50 identify identify VBP work_lbjz23isnfbh5bcl4jbmahp6r4 241 51 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 241 52 presence presence NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 53 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 241 54 severity severity NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 55 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 241 56 non non JJ work_lbjz23isnfbh5bcl4jbmahp6r4 241 57 - - JJ work_lbjz23isnfbh5bcl4jbmahp6r4 241 58 alcoholic alcoholic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 241 59 fatty fatty NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 60 liver liver NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 61 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 62 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 241 63 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 241 64 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 242 1 BMC BMC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 242 2 Medicine Medicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 242 3 2019 2019 CD work_lbjz23isnfbh5bcl4jbmahp6r4 242 4 17 17 CD work_lbjz23isnfbh5bcl4jbmahp6r4 242 5 85 85 CD work_lbjz23isnfbh5bcl4jbmahp6r4 242 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 243 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 243 2 https://doi.org/10.1186/s12916-019-1319-4 https://doi.org/10.1186/s12916-019-1319-4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 243 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 243 4 24 24 CD work_lbjz23isnfbh5bcl4jbmahp6r4 243 5 Ridker ridker NN work_lbjz23isnfbh5bcl4jbmahp6r4 243 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 7 PM pm NN work_lbjz23isnfbh5bcl4jbmahp6r4 243 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 243 9 Howard Howard NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 11 CP CP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 243 13 Walter Walter NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 15 V V NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 243 17 Everett Everett NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 19 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 243 21 Libby Libby NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 23 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 243 25 Hensen Hensen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 27 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 243 29 Thuren Thuren NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 243 31 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 32 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 243 33 CANTOS CANTOS NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 34 Pilot Pilot NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 35 Investigative Investigative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 36 Group Group NNP work_lbjz23isnfbh5bcl4jbmahp6r4 243 37 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 244 1 Effects effect NNS work_lbjz23isnfbh5bcl4jbmahp6r4 244 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 244 3 interleukin-1β interleukin-1β CD work_lbjz23isnfbh5bcl4jbmahp6r4 244 4 inhibition inhibition NN work_lbjz23isnfbh5bcl4jbmahp6r4 244 5 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 244 6 canakinumab canakinumab NNS work_lbjz23isnfbh5bcl4jbmahp6r4 244 7 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 244 8 hemoglobin hemoglobin NN work_lbjz23isnfbh5bcl4jbmahp6r4 244 9 A1c A1c NNP work_lbjz23isnfbh5bcl4jbmahp6r4 244 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 244 11 lipids lipid NNS work_lbjz23isnfbh5bcl4jbmahp6r4 244 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 244 13 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 244 14 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 244 15 reactive reactive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 244 16 protein protein NN work_lbjz23isnfbh5bcl4jbmahp6r4 244 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 244 18 interleukin-6 interleukin-6 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 244 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 244 20 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 244 21 fibrinogen fibrinogen VB work_lbjz23isnfbh5bcl4jbmahp6r4 244 22 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 244 23 phase phase NN work_lbjz23isnfbh5bcl4jbmahp6r4 244 24 IIb iib RB work_lbjz23isnfbh5bcl4jbmahp6r4 244 25 randomized randomize VBN work_lbjz23isnfbh5bcl4jbmahp6r4 244 26 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 244 27 placebo placebo NN work_lbjz23isnfbh5bcl4jbmahp6r4 244 28 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 244 29 controlled control VBN work_lbjz23isnfbh5bcl4jbmahp6r4 244 30 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 244 31 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 245 1 Circulation circulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 245 2 2012 2012 CD work_lbjz23isnfbh5bcl4jbmahp6r4 245 3 126 126 CD work_lbjz23isnfbh5bcl4jbmahp6r4 245 4 2739–2748 2739–2748 CD work_lbjz23isnfbh5bcl4jbmahp6r4 245 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 246 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 246 2 https://doi.org/10.1161/ https://doi.org/10.1161/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 3 CIRCULATIONAHA.112.122556 CIRCULATIONAHA.112.122556 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 246 5 25 25 CD work_lbjz23isnfbh5bcl4jbmahp6r4 246 6 Larsen Larsen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 8 CM CM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 246 10 Faulenbach Faulenbach NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 12 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 246 14 Vaag Vaag NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 16 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 246 18 Vølund Vølund NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 20 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 246 22 Ehses Ehses NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 24 JA JA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 246 26 Seifert Seifert NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 27   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 28 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 29 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 246 30 Mandrup Mandrup NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 31 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 246 32 Poulsen Poulsen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 33   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 34 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 35 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 246 36 Donath Donath NNP work_lbjz23isnfbh5bcl4jbmahp6r4 246 37   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 246 38 MY my NN work_lbjz23isnfbh5bcl4jbmahp6r4 246 39 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 247 1 Interleukin-1-receptor Interleukin-1-receptor NNP work_lbjz23isnfbh5bcl4jbmahp6r4 247 2 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 247 3 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 247 4 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 247 5 2 2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 247 6 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 247 7 mellitus mellitus NN work_lbjz23isnfbh5bcl4jbmahp6r4 247 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 248 1 New New NNP work_lbjz23isnfbh5bcl4jbmahp6r4 248 2 England England NNP work_lbjz23isnfbh5bcl4jbmahp6r4 248 3 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 248 4 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 248 5 Medicine Medicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 248 6 2007 2007 CD work_lbjz23isnfbh5bcl4jbmahp6r4 248 7 356 356 CD work_lbjz23isnfbh5bcl4jbmahp6r4 248 8 1517–1526 1517–1526 CD work_lbjz23isnfbh5bcl4jbmahp6r4 248 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 249 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 249 2 https://doi.org/10.1056/NEJMoa065213 https://doi.org/10.1056/nejmoa065213 NN work_lbjz23isnfbh5bcl4jbmahp6r4 249 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 249 4 26 26 CD work_lbjz23isnfbh5bcl4jbmahp6r4 249 5 Ridker ridker NN work_lbjz23isnfbh5bcl4jbmahp6r4 249 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 7 PM pm NN work_lbjz23isnfbh5bcl4jbmahp6r4 249 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 9 Everett Everett NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 11 BM BM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 13 Thuren thuren NN work_lbjz23isnfbh5bcl4jbmahp6r4 249 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 15 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 17 MacFadyen MacFadyen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 19 JG JG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 21 Chang Chang NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 23 WH WH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 24 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 25 Ballantyne Ballantyne NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 27 C C NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 28 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 29 Fonseca Fonseca NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 30   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 31 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 32 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 33 Nicolau Nicolau NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 34   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 35 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 36 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 37 Koenig Koenig NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 38   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 39 W W NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 40 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 41 Anker Anker NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 42   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 43 SD SD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 44 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 249 45 et et NN work_lbjz23isnfbh5bcl4jbmahp6r4 249 46   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 249 47 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 249 48 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 250 1 Antiinflammatory antiinflammatory JJ work_lbjz23isnfbh5bcl4jbmahp6r4 250 2 therapy therapy NN work_lbjz23isnfbh5bcl4jbmahp6r4 250 3 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 250 4 canakinumab canakinumab NNS work_lbjz23isnfbh5bcl4jbmahp6r4 250 5 for for IN work_lbjz23isnfbh5bcl4jbmahp6r4 250 6 atherosclerotic atherosclerotic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 250 7 disease disease NN work_lbjz23isnfbh5bcl4jbmahp6r4 250 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 251 1 New New NNP work_lbjz23isnfbh5bcl4jbmahp6r4 251 2 England England NNP work_lbjz23isnfbh5bcl4jbmahp6r4 251 3 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 251 4 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 251 5 Medicine Medicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 251 6 2017 2017 CD work_lbjz23isnfbh5bcl4jbmahp6r4 251 7 377 377 CD work_lbjz23isnfbh5bcl4jbmahp6r4 251 8 1119–1131 1119–1131 CD work_lbjz23isnfbh5bcl4jbmahp6r4 251 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 252 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 252 2 https://doi.org/10.1056/NEJMoa1707914 https://doi.org/10.1056/NEJMoa1707914 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 252 4 27 27 CD work_lbjz23isnfbh5bcl4jbmahp6r4 252 5 Nakatsuru nakatsuru NN work_lbjz23isnfbh5bcl4jbmahp6r4 252 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 252 7 K K NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 252 9 Ohgo Ohgo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 252 11 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 252 13 Oki Oki NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 252 15 Y Y NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 16 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 252 17 Matsukura Matsukura NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 252 19 S. S. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 20 Interleukin-1 Interleukin-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 21 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 252 22 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 23 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 252 24 stimulates stimulate VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 252 25 arginine arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 26 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 27 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 252 28 AVP AVP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 29 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 252 30 release release VBP work_lbjz23isnfbh5bcl4jbmahp6r4 252 31 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 252 32 superfused superfused JJ work_lbjz23isnfbh5bcl4jbmahp6r4 252 33 rat rat NNP work_lbjz23isnfbh5bcl4jbmahp6r4 252 34 hypothalamo hypothalamo JJ work_lbjz23isnfbh5bcl4jbmahp6r4 252 35 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 252 36 neurohypophyseal neurohypophyseal NN work_lbjz23isnfbh5bcl4jbmahp6r4 252 37 complexes complex NNS work_lbjz23isnfbh5bcl4jbmahp6r4 252 38 independently independently RB work_lbjz23isnfbh5bcl4jbmahp6r4 252 39 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 252 40 cholinergic cholinergic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 252 41 mechanism mechanism NN work_lbjz23isnfbh5bcl4jbmahp6r4 252 42 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 253 1 Brain Brain NNP work_lbjz23isnfbh5bcl4jbmahp6r4 253 2 Research Research NNP work_lbjz23isnfbh5bcl4jbmahp6r4 253 3 1991 1991 CD work_lbjz23isnfbh5bcl4jbmahp6r4 253 4 554 554 CD work_lbjz23isnfbh5bcl4jbmahp6r4 253 5 38–45 38–45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 253 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 254 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 254 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 254 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 255 1 org/10.1016/0006 org/10.1016/0006 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 2 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 255 3 8993(91)90169-v 8993(91)90169-v CD work_lbjz23isnfbh5bcl4jbmahp6r4 255 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 255 5 28 28 CD work_lbjz23isnfbh5bcl4jbmahp6r4 255 6 Watanobe Watanobe NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 255 8 H H NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 9 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 255 10 Takebe Takebe NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 255 12 K. K. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 13 Intrahypothalamic intrahypothalamic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 255 14 perfusion perfusion NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 15 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 255 16 interleukin-1-beta interleukin-1-beta NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 17 stimulates stimulate VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 255 18 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 255 19 local local JJ work_lbjz23isnfbh5bcl4jbmahp6r4 255 20 release release NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 21 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 255 22 corticotropin- corticotropin- NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 23 releasing release VBG work_lbjz23isnfbh5bcl4jbmahp6r4 255 24 hormone hormone NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 25 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 255 26 arginine arginine VB work_lbjz23isnfbh5bcl4jbmahp6r4 255 27 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 28 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 255 29 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 255 30 plasma plasma NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 31 adrenocorticotropin adrenocorticotropin VBP work_lbjz23isnfbh5bcl4jbmahp6r4 255 32 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 255 33 freely freely RB work_lbjz23isnfbh5bcl4jbmahp6r4 255 34 moving moving JJ work_lbjz23isnfbh5bcl4jbmahp6r4 255 35 rats rat NNS work_lbjz23isnfbh5bcl4jbmahp6r4 255 36 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 255 37 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 255 38 comparative comparative JJ work_lbjz23isnfbh5bcl4jbmahp6r4 255 39 perfusion perfusion NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 40 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 255 41 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 255 42 paraventricular paraventricular NNP work_lbjz23isnfbh5bcl4jbmahp6r4 255 43 nucleus nucleus NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 44 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 255 45 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 255 46 median median JJ work_lbjz23isnfbh5bcl4jbmahp6r4 255 47 eminence eminence NN work_lbjz23isnfbh5bcl4jbmahp6r4 255 48 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 256 1 Neuroendocrinology neuroendocrinology NN work_lbjz23isnfbh5bcl4jbmahp6r4 256 2 1993 1993 CD work_lbjz23isnfbh5bcl4jbmahp6r4 256 3 57 57 CD work_lbjz23isnfbh5bcl4jbmahp6r4 256 4 593–599 593–599 CD work_lbjz23isnfbh5bcl4jbmahp6r4 256 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 257 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 257 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 257 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 258 1 org/10.1159/000126412 org/10.1159/000126412 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 258 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 258 3 29 29 CD work_lbjz23isnfbh5bcl4jbmahp6r4 258 4 Raber Raber NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 5   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 258 6 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 7 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 258 8 Pich Pich NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 9   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 258 10 EM EM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 11 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 258 12 Koob Koob NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 258 14 GF GF NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 15 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 258 16 Bloom Bloom NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 17   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 258 18 FE FE NNP work_lbjz23isnfbh5bcl4jbmahp6r4 258 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 259 1 IL-1 il-1 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 259 2 beta beta NN work_lbjz23isnfbh5bcl4jbmahp6r4 259 3 potentiates potentiate VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 259 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 259 5 acetylcholine acetylcholine NN work_lbjz23isnfbh5bcl4jbmahp6r4 259 6 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 259 7 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 259 8 release release NN work_lbjz23isnfbh5bcl4jbmahp6r4 259 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 259 10 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 259 11 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 259 12 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 259 13 hypothalamus hypothalamus NN work_lbjz23isnfbh5bcl4jbmahp6r4 259 14 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 259 15 vitro vitro FW work_lbjz23isnfbh5bcl4jbmahp6r4 259 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 259 17 but but CC work_lbjz23isnfbh5bcl4jbmahp6r4 259 18 not not RB work_lbjz23isnfbh5bcl4jbmahp6r4 259 19 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 259 20 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 259 21 amygdala amygdala NNP work_lbjz23isnfbh5bcl4jbmahp6r4 259 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 260 1 Neuroendocrinology neuroendocrinology NN work_lbjz23isnfbh5bcl4jbmahp6r4 260 2 1994 1994 CD work_lbjz23isnfbh5bcl4jbmahp6r4 260 3 59 59 CD work_lbjz23isnfbh5bcl4jbmahp6r4 260 4 208–217 208–217 CD work_lbjz23isnfbh5bcl4jbmahp6r4 260 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 261 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 261 2 https://doi.org/10.1159/000126661 https://doi.org/10.1159/000126661 JJ work_lbjz23isnfbh5bcl4jbmahp6r4 261 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 261 4 30 30 CD work_lbjz23isnfbh5bcl4jbmahp6r4 261 5 Wahab wahab NN work_lbjz23isnfbh5bcl4jbmahp6r4 261 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 261 7 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 261 9 Tazinafo Tazinafo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 261 11 LF LF NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 12 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 261 13 Cárnio Cárnio NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 261 15 EC EC NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 16 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 261 17 Aguila Aguila NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 18   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 261 19 FA FA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 20 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 261 21 Batalhão Batalhão NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 22   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 261 23 ME ME NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 24 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 261 25 Rocha Rocha NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 261 27 MJ MJ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 261 28 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 262 1 Interleukin-1 Interleukin-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 262 2 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 262 3 antagonist antagonist NN work_lbjz23isnfbh5bcl4jbmahp6r4 262 4 decreases decrease VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 262 5 cerebrospinal cerebrospinal JJ work_lbjz23isnfbh5bcl4jbmahp6r4 262 6 fluid fluid JJ work_lbjz23isnfbh5bcl4jbmahp6r4 262 7 nitric nitric JJ work_lbjz23isnfbh5bcl4jbmahp6r4 262 8 oxide oxide NN work_lbjz23isnfbh5bcl4jbmahp6r4 262 9 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 262 10 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 262 11 increases increase VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 262 12 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 262 13 secretion secretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 262 14 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 262 15 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 262 16 late late JJ work_lbjz23isnfbh5bcl4jbmahp6r4 262 17 phase phase NN work_lbjz23isnfbh5bcl4jbmahp6r4 262 18 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 262 19 sepsis sepsis NN work_lbjz23isnfbh5bcl4jbmahp6r4 262 20 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 262 21 rats rat NNS work_lbjz23isnfbh5bcl4jbmahp6r4 262 22 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 263 1 Endocrine Endocrine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 263 2 2015 2015 CD work_lbjz23isnfbh5bcl4jbmahp6r4 263 3 49 49 CD work_lbjz23isnfbh5bcl4jbmahp6r4 263 4 215–221 215–221 CD work_lbjz23isnfbh5bcl4jbmahp6r4 263 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 264 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 264 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 264 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 265 1 org/10.1007 org/10.1007 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 2 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 265 3 s12020 s12020 NN work_lbjz23isnfbh5bcl4jbmahp6r4 265 4 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 265 5 014 014 CD work_lbjz23isnfbh5bcl4jbmahp6r4 265 6 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 265 7 0452 0452 CD work_lbjz23isnfbh5bcl4jbmahp6r4 265 8 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 265 9 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 265 10 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 265 11 31 31 CD work_lbjz23isnfbh5bcl4jbmahp6r4 265 12 Ebrahimi ebrahimi NN work_lbjz23isnfbh5bcl4jbmahp6r4 265 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 14 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 15 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 16 Urwyler Urwyler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 17   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 18 SA SA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 20 Straumann Straumann NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 21   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 22 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 23 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 24 Doerpfeld Doerpfeld NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 25   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 26 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 27 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 28 Bernasconi Bernasconi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 29   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 30 L L NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 32 Neyer Neyer NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 33   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 34 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 35 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 36 Schuetz Schuetz NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 37   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 38 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 39 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 40 Mueller Mueller NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 41   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 42 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 43 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 265 44 Donath Donath NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 45   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 46 MY MY NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 47 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 265 48 Christ Christ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 49 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 265 50 Crain Crain NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 51   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 265 52 M. M. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 53 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 265 54 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 265 55 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 265 56 men man NNS work_lbjz23isnfbh5bcl4jbmahp6r4 265 57 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 265 58 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 265 59 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 265 60 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 265 61 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 265 62 testosterone testosterone NN work_lbjz23isnfbh5bcl4jbmahp6r4 265 63 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 265 64 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 265 65 randomized randomized JJ work_lbjz23isnfbh5bcl4jbmahp6r4 265 66 clinical clinical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 265 67 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 265 68 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 266 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 266 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 266 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 266 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 266 5 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 266 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 266 7 2018 2018 CD work_lbjz23isnfbh5bcl4jbmahp6r4 266 8 103 103 CD work_lbjz23isnfbh5bcl4jbmahp6r4 266 9 3466–3476 3466–3476 CD work_lbjz23isnfbh5bcl4jbmahp6r4 266 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 267 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 267 2 https://doi.org/10.1210/jc.2018- https://doi.org/10.1210/jc.2018- NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 3 00739 00739 CD work_lbjz23isnfbh5bcl4jbmahp6r4 267 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 267 5 32 32 CD work_lbjz23isnfbh5bcl4jbmahp6r4 267 6 Urwyler Urwyler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 267 8 SA SA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 267 10 Schuetz Schuetz NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 267 12 P P NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 267 14 Ebrahimi Ebrahimi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 267 16 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 267 18 Donath Donath NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 267 20 MY MY NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 21 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 267 22 Christ Christ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 23 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 267 24 Crain Crain NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 25   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 267 26 M. M. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 27 Interleukin-1 Interleukin-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 267 28 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 267 29 decreases decrease VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 267 30 cortisol cortisol NN work_lbjz23isnfbh5bcl4jbmahp6r4 267 31 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 267 32 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 267 33 obese obese JJ work_lbjz23isnfbh5bcl4jbmahp6r4 267 34 individuals individual NNS work_lbjz23isnfbh5bcl4jbmahp6r4 267 35 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 268 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 268 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 268 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 268 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 268 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 268 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 268 7 2017 2017 CD work_lbjz23isnfbh5bcl4jbmahp6r4 268 8 102 102 CD work_lbjz23isnfbh5bcl4jbmahp6r4 268 9 1712–1718 1712–1718 CD work_lbjz23isnfbh5bcl4jbmahp6r4 268 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 269 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 269 2 https://doi.org/10.1210/jc.2016-3931 https://doi.org/10.1210/jc.2016-3931 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 269 4 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 269 5 Friedewald Friedewald NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 269 7 WT WT NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 269 9 Levy Levy NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 269 11 RI RI NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 12 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 269 13 Fredrickson Fredrickson NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 269 15 DS DS NNP work_lbjz23isnfbh5bcl4jbmahp6r4 269 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 270 1 Estimation estimation NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 270 3 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 270 4 concentration concentration NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 5 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 270 6 low low JJ work_lbjz23isnfbh5bcl4jbmahp6r4 270 7 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 270 8 density density NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 9 lipoprotein lipoprotein NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 10 cholesterol cholesterol NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 11 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 270 12 plasma plasma NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 270 14 Without without IN work_lbjz23isnfbh5bcl4jbmahp6r4 270 15 use use NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 16 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 270 17 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 270 18 preparative preparative JJ work_lbjz23isnfbh5bcl4jbmahp6r4 270 19 ultracentrifuge ultracentrifuge NN work_lbjz23isnfbh5bcl4jbmahp6r4 270 20 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 271 1 Clinical clinical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 271 2 Chemistry Chemistry NNP work_lbjz23isnfbh5bcl4jbmahp6r4 271 3 1972 1972 CD work_lbjz23isnfbh5bcl4jbmahp6r4 271 4 18 18 CD work_lbjz23isnfbh5bcl4jbmahp6r4 271 5 499–502 499–502 CD work_lbjz23isnfbh5bcl4jbmahp6r4 271 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 272 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 272 2 https://doi.org/10.1093/ https://doi.org/10.1093/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 3 clinchem/18.6.499 clinchem/18.6.499 ADD work_lbjz23isnfbh5bcl4jbmahp6r4 272 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 272 5 34 34 CD work_lbjz23isnfbh5bcl4jbmahp6r4 272 6 Saleem saleem NN work_lbjz23isnfbh5bcl4jbmahp6r4 272 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 8 U u NN work_lbjz23isnfbh5bcl4jbmahp6r4 272 9 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 272 10 Khaleghi Khaleghi NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 12 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 272 14 Morgenthaler Morgenthaler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 15   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 16 NG NG NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 272 18 Bergmann Bergmann NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 19   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 20 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 21 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 272 22 Struck Struck NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 23   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 24 J J NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 25 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 272 26 Mosley Mosley NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 27   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 28 TH TH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 29 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 272 30 Kullo Kullo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 31   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 272 32 IJ IJ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 272 33 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 273 1 Plasma plasma NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 2 carboxy carboxy NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 3 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 273 4 terminal terminal NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 5 provasopressin provasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 6 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 273 7 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 273 8 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 273 9 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 273 10 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 273 11 novel novel JJ work_lbjz23isnfbh5bcl4jbmahp6r4 273 12 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 13 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 273 14 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 15 resistance resistance NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 273 17 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 273 18 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 273 19 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 274 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 274 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 274 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 274 4 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 274 5 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 274 6 Metabolism Metabolism NNP work_lbjz23isnfbh5bcl4jbmahp6r4 274 7 2009 2009 CD work_lbjz23isnfbh5bcl4jbmahp6r4 274 8 94 94 CD work_lbjz23isnfbh5bcl4jbmahp6r4 274 9 2558–2564 2558–2564 CD work_lbjz23isnfbh5bcl4jbmahp6r4 274 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 275 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 275 2 https://doi.org/10.1210/jc.2008-2278 https://doi.org/10.1210/jc.2008-2278 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 275 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 275 4 35 35 CD work_lbjz23isnfbh5bcl4jbmahp6r4 275 5 Kahn Kahn NNP work_lbjz23isnfbh5bcl4jbmahp6r4 275 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 275 7 BB BB NNP work_lbjz23isnfbh5bcl4jbmahp6r4 275 8 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 275 9 Flier Flier NNP work_lbjz23isnfbh5bcl4jbmahp6r4 275 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 275 11 JS JS NNP work_lbjz23isnfbh5bcl4jbmahp6r4 275 12 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 276 1 Obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 276 2 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 276 3 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 276 4 resistance resistance NN work_lbjz23isnfbh5bcl4jbmahp6r4 276 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 277 1 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 277 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 277 3 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 277 4 Investigation Investigation NNP work_lbjz23isnfbh5bcl4jbmahp6r4 277 5 2000 2000 CD work_lbjz23isnfbh5bcl4jbmahp6r4 277 6 106 106 CD work_lbjz23isnfbh5bcl4jbmahp6r4 277 7 473–481 473–481 CD work_lbjz23isnfbh5bcl4jbmahp6r4 277 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 278 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 278 2 https://doi.org/10.1172/ https://doi.org/10.1172/ UH work_lbjz23isnfbh5bcl4jbmahp6r4 278 3 JCI10842 JCI10842 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 278 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 278 5 36 36 CD work_lbjz23isnfbh5bcl4jbmahp6r4 278 6 Monteiro Monteiro NNP work_lbjz23isnfbh5bcl4jbmahp6r4 278 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 278 8 R r NN work_lbjz23isnfbh5bcl4jbmahp6r4 278 9 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 278 10 Azevedo Azevedo NNP work_lbjz23isnfbh5bcl4jbmahp6r4 278 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 278 12 I. I. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 279 1 Chronic chronic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 279 2 inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 279 3 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 279 4 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 279 5 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 279 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 279 7 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 279 8 syndrome syndrome NN work_lbjz23isnfbh5bcl4jbmahp6r4 279 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 280 1 Mediators mediator NNS work_lbjz23isnfbh5bcl4jbmahp6r4 280 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 280 3 Inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 280 4 2010 2010 CD work_lbjz23isnfbh5bcl4jbmahp6r4 280 5 2010 2010 CD work_lbjz23isnfbh5bcl4jbmahp6r4 280 6 289645 289645 CD work_lbjz23isnfbh5bcl4jbmahp6r4 280 7 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 281 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 281 2 https://doi.org/10.1155/2010/289645 https://doi.org/10.1155/2010/289645 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 281 4 37 37 CD work_lbjz23isnfbh5bcl4jbmahp6r4 281 5 Aharon Aharon NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 6 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 281 7 Hananel Hananel NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 8   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 281 9 G G NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 281 11 Jörns Jörns NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 12   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 281 13 A A NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 281 15 Lenzen Lenzen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 16   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 281 17 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 281 19 Raz Raz NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 20   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 281 21 I -PRON- PRP work_lbjz23isnfbh5bcl4jbmahp6r4 281 22 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 281 23 Weksler Weksler NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 24 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 281 25 Zangen Zangen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 26   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 281 27 S. S. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 28 Antidiabetic Antidiabetic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 29 effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 30 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 281 31 interleukin-1β interleukin-1β JJ work_lbjz23isnfbh5bcl4jbmahp6r4 281 32 antibody antibody NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 33 therapy therapy NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 34 through through IN work_lbjz23isnfbh5bcl4jbmahp6r4 281 35 β β NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 36 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 281 37 cell cell NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 38 protection protection NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 39 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 281 40 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 281 41 Cohen Cohen NNP work_lbjz23isnfbh5bcl4jbmahp6r4 281 42 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 43 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 281 44 sensitive sensitive JJ work_lbjz23isnfbh5bcl4jbmahp6r4 281 45 rat rat NN work_lbjz23isnfbh5bcl4jbmahp6r4 281 46 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 282 1 Diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 282 2 2015 2015 CD work_lbjz23isnfbh5bcl4jbmahp6r4 282 3 64 64 CD work_lbjz23isnfbh5bcl4jbmahp6r4 282 4 1780–1785 1780–1785 CD work_lbjz23isnfbh5bcl4jbmahp6r4 282 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 283 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 283 2 https://doi.org/10.2337/db14-1018 https://doi.org/10.2337/db14-1018 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 283 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 283 4 38 38 CD work_lbjz23isnfbh5bcl4jbmahp6r4 283 5 Donath Donath NNP work_lbjz23isnfbh5bcl4jbmahp6r4 283 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 283 7 MY my NN work_lbjz23isnfbh5bcl4jbmahp6r4 283 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 284 1 Inflammation inflammation NN work_lbjz23isnfbh5bcl4jbmahp6r4 284 2 as as IN work_lbjz23isnfbh5bcl4jbmahp6r4 284 3 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 284 4 sensor sensor NN work_lbjz23isnfbh5bcl4jbmahp6r4 284 5 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 284 6 metabolic metabolic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 284 7 stress stress NN work_lbjz23isnfbh5bcl4jbmahp6r4 284 8 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 284 9 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 284 10 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 284 11 type type NN work_lbjz23isnfbh5bcl4jbmahp6r4 284 12 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 284 13 diabetes diabetes NN work_lbjz23isnfbh5bcl4jbmahp6r4 284 14 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 285 1 Endocrinology Endocrinology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 285 2 2011 2011 CD work_lbjz23isnfbh5bcl4jbmahp6r4 285 3 152 152 CD work_lbjz23isnfbh5bcl4jbmahp6r4 285 4 4005–4006 4005–4006 CD work_lbjz23isnfbh5bcl4jbmahp6r4 285 5 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 286 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 286 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 286 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 287 1 org/10.1210 org/10.1210 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 287 2 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 287 3 en.2011 en.2011 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 287 4 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 287 5 1691 1691 CD work_lbjz23isnfbh5bcl4jbmahp6r4 287 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 287 7 39 39 CD work_lbjz23isnfbh5bcl4jbmahp6r4 287 8 Davy Davy NNP work_lbjz23isnfbh5bcl4jbmahp6r4 287 9   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 287 10 KP KP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 287 11 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 287 12 Orr Orr NNP work_lbjz23isnfbh5bcl4jbmahp6r4 287 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 287 14 JS JS NNP work_lbjz23isnfbh5bcl4jbmahp6r4 287 15 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 288 1 Sympathetic sympathetic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 288 2 nervous nervous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 288 3 system system NN work_lbjz23isnfbh5bcl4jbmahp6r4 288 4 behavior behavior NN work_lbjz23isnfbh5bcl4jbmahp6r4 288 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 288 6 human human JJ work_lbjz23isnfbh5bcl4jbmahp6r4 288 7 obesity obesity NN work_lbjz23isnfbh5bcl4jbmahp6r4 288 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 289 1 Neuroscience Neuroscience NNP work_lbjz23isnfbh5bcl4jbmahp6r4 289 2 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 289 3 Biobehavioral Biobehavioral NNP work_lbjz23isnfbh5bcl4jbmahp6r4 289 4 Reviews Reviews NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 289 5 2009 2009 CD work_lbjz23isnfbh5bcl4jbmahp6r4 289 6 33 33 CD work_lbjz23isnfbh5bcl4jbmahp6r4 289 7 116–124 116–124 CD work_lbjz23isnfbh5bcl4jbmahp6r4 289 8 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 290 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 290 2 https://doi.org/10.1016/j.neubiorev.2008.05.024 https://doi.org/10.1016/j.neubiorev.2008.05.024 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 290 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 290 4 40 40 CD work_lbjz23isnfbh5bcl4jbmahp6r4 290 5 Schrier Schrier NNP work_lbjz23isnfbh5bcl4jbmahp6r4 290 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 290 7 RW RW NNP work_lbjz23isnfbh5bcl4jbmahp6r4 290 8 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 290 9 Goldberg Goldberg NNP work_lbjz23isnfbh5bcl4jbmahp6r4 290 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 290 11 JP JP NNP work_lbjz23isnfbh5bcl4jbmahp6r4 290 12 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 291 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 291 2 physiology physiology NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 291 4 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 5 release release NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 6 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 291 7 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 291 8 pathogenesis pathogenesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 9 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 291 10 impaired impaired JJ work_lbjz23isnfbh5bcl4jbmahp6r4 291 11 water water NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 12 excretion excretion NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 13 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 291 14 adrenal adrenal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 291 15 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 291 16 thyroid thyroid NN work_lbjz23isnfbh5bcl4jbmahp6r4 291 17 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 291 18 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 291 19 edematous edematous JJ work_lbjz23isnfbh5bcl4jbmahp6r4 291 20 disorders disorder NNS work_lbjz23isnfbh5bcl4jbmahp6r4 291 21 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 292 1 Yale Yale NNP work_lbjz23isnfbh5bcl4jbmahp6r4 292 2 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 292 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 292 4 Biology Biology NNP work_lbjz23isnfbh5bcl4jbmahp6r4 292 5 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 292 6 Medicine Medicine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 292 7 1980 1980 CD work_lbjz23isnfbh5bcl4jbmahp6r4 292 8 53 53 CD work_lbjz23isnfbh5bcl4jbmahp6r4 292 9 525–541 525–541 CD work_lbjz23isnfbh5bcl4jbmahp6r4 292 10 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 293 1 41 41 CD work_lbjz23isnfbh5bcl4jbmahp6r4 293 2 Loncar loncar NN work_lbjz23isnfbh5bcl4jbmahp6r4 293 3   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 4 G g NN work_lbjz23isnfbh5bcl4jbmahp6r4 293 5 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 6 von von NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 7 Haehling Haehling NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 8   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 9 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 10 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 11 Tahirovic Tahirovic VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 293 12   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 13 E e NN work_lbjz23isnfbh5bcl4jbmahp6r4 293 14 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 15 Inkrot Inkrot NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 16   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 17 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 18 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 19 Mende Mende NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 20   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 21 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 22 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 23 Sekularac Sekularac NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 24   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 25 N N NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 26 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 27 Lainscak Lainscak NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 28   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 29 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 30 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 31 Apostolovic Apostolovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 32   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 33 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 34 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 35 Putnikovic Putnikovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 36   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 37 B b NN work_lbjz23isnfbh5bcl4jbmahp6r4 293 38 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 39 Edelmann Edelmann NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 40   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 41 F F NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 42 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 293 43 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 44   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 293 45 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 293 46 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 294 1 Effect effect NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 2 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 294 3 beta beta JJ work_lbjz23isnfbh5bcl4jbmahp6r4 294 4 blockade blockade NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 5 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 294 6 natriuretic natriuretic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 294 7 peptides peptide NNS work_lbjz23isnfbh5bcl4jbmahp6r4 294 8 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 294 9 copeptin copeptin NNS work_lbjz23isnfbh5bcl4jbmahp6r4 294 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 294 11 elderly elderly JJ work_lbjz23isnfbh5bcl4jbmahp6r4 294 12 patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 294 13 with with IN work_lbjz23isnfbh5bcl4jbmahp6r4 294 14 heart heart NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 15 failure failure NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 16 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 294 17 preserved preserve VBN work_lbjz23isnfbh5bcl4jbmahp6r4 294 18 or or CC work_lbjz23isnfbh5bcl4jbmahp6r4 294 19 reduced reduce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 294 20 ejection ejection NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 21 fraction fraction NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 22 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 294 23 results result NNS work_lbjz23isnfbh5bcl4jbmahp6r4 294 24 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 294 25 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 294 26 CIBIS CIBIS NNP work_lbjz23isnfbh5bcl4jbmahp6r4 294 27 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 294 28 ELD ELD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 294 29 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 294 30 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 295 1 Clinical Clinical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 295 2 Biochemistry Biochemistry NNP work_lbjz23isnfbh5bcl4jbmahp6r4 295 3 2012 2012 CD work_lbjz23isnfbh5bcl4jbmahp6r4 295 4 45 45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 295 5 117–122 117–122 CD work_lbjz23isnfbh5bcl4jbmahp6r4 295 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 296 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 296 2 https://doi.org/10.1016/j https://doi.org/10.1016/j NNP work_lbjz23isnfbh5bcl4jbmahp6r4 296 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 297 1 clinbiochem.2011.11.010 clinbiochem.2011.11.010 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 2 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 297 3 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 297 4 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 297 5 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 297 6 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 297 7 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 297 8 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 297 9 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 10 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 11 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 12 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 297 13 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 14 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 297 15 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 16 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 17 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 297 18 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 19 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 297 20 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 297 21 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 297 22 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 297 23 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 297 24 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 25 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 26 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 297 27 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 297 28 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 29 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 297 30 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 297 31 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 32 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 297 33 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 297 34 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 297 35 https://doi.org/10.1016/j.ijcard.2015.04.134 https://doi.org/10.1016/j.ijcard.2015.04.134 UH work_lbjz23isnfbh5bcl4jbmahp6r4 297 36 https://doi.org/10.1016/J.AHJ.2014.11.020 https://doi.org/10.1016/J.AHJ.2014.11.020 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 37 https://doi.org/10.1016/J.AHJ.2014.11.020 https://doi.org/10.1016/J.AHJ.2014.11.020 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 38 https://doi.org/10.1055/s-2007-978899 https://doi.org/10.1055/s-2007-978899 ADD work_lbjz23isnfbh5bcl4jbmahp6r4 297 39 https://doi.org/10.1016/s0024-3205(98)00027-7 https://doi.org/10.1016/s0024-3205(98)00027-7 VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 297 40 https://doi.org/10.1210/jcem.84.6.5775 https://doi.org/10.1210/jcem.84.6.5775 PRP$ work_lbjz23isnfbh5bcl4jbmahp6r4 297 41 https://doi.org/10.1042/bj1360705 https://doi.org/10.1042/bj1360705 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 42 https://doi.org/10.1210/me.2006-0069 https://doi.org/10.1210/me.2006-0069 UH work_lbjz23isnfbh5bcl4jbmahp6r4 297 43 https://doi.org/10.1016/0049-3848(87)90252-0 https://doi.org/10.1016/0049-3848(87)90252-0 UH work_lbjz23isnfbh5bcl4jbmahp6r4 297 44 https://doi.org/10.1016/0049-3848(87)90252-0 https://doi.org/10.1016/0049-3848(87)90252-0 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 45 https://doi.org/10.1161/01.cir.83.6.2111 https://doi.org/10.1161/01.cir.83.6.2111 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 46 https://doi.org/10.1210/jc.2010-2981 https://doi.org/10.1210/jc.2010-2981 NN work_lbjz23isnfbh5bcl4jbmahp6r4 297 47 https://doi.org/10.1210/JC.2015-2362 https://doi.org/10.1210/jc.2015-2362 VBP work_lbjz23isnfbh5bcl4jbmahp6r4 297 48 https://doi.org/10.1186/s12916-019-1319-4 https://doi.org/10.1186/s12916-019-1319-4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 297 49 https://doi.org/10.1161/CIRCULATIONAHA.112.122556 https://doi.org/10.1161/CIRCULATIONAHA.112.122556 -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 297 50 https://doi.org/10.1161/CIRCULATIONAHA.112.122556 https://doi.org/10.1161/circulationaha.112.122556 ADD work_lbjz23isnfbh5bcl4jbmahp6r4 297 51 https://doi.org/10.1056/NEJMoa065213 https://doi.org/10.1056/nejmoa065213 IN work_lbjz23isnfbh5bcl4jbmahp6r4 297 52 https://doi.org/10.1056/NEJMoa1707914 https://doi.org/10.1056/NEJMoa1707914 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 53 https://doi.org/10.1016/0006-8993(91)90169-v https://doi.org/10.1016/0006-8993(91)90169-v NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 54 https://doi.org/10.1016/0006-8993(91)90169-v https://doi.org/10.1016/0006-8993(91)90169-v NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 55 https://doi.org/10.1159/000126412 https://doi.org/10.1159/000126412 FW work_lbjz23isnfbh5bcl4jbmahp6r4 297 56 https://doi.org/10.1159/000126412 https://doi.org/10.1159/000126412 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 57 https://doi.org/10.1159/000126661 https://doi.org/10.1159/000126661 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 58 https://doi.org/10.1007/s12020-014-0452-2 https://doi.org/10.1007/s12020-014-0452-2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 297 59 https://doi.org/10.1007/s12020-014-0452-2 https://doi.org/10.1007/s12020-014-0452-2 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 60 https://doi.org/10.1210/jc.2018-00739 https://doi.org/10.1210/jc.2018-00739 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 61 https://doi.org/10.1210/jc.2018-00739 https://doi.org/10.1210/jc.2018-00739 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 62 https://doi.org/10.1210/jc.2016-3931 https://doi.org/10.1210/jc.2016-3931 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 63 https://doi.org/10.1093/clinchem/18.6.499 https://doi.org/10.1093/clinchem/18.6.499 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 64 https://doi.org/10.1093/clinchem/18.6.499 https://doi.org/10.1093/clinchem/18.6.499 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 65 https://doi.org/10.1210/jc.2008-2278 https://doi.org/10.1210/jc.2008-2278 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 66 https://doi.org/10.1172/JCI10842 https://doi.org/10.1172/JCI10842 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 67 https://doi.org/10.1172/JCI10842 https://doi.org/10.1172/JCI10842 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 68 https://doi.org/10.1155/2010/289645 https://doi.org/10.1155/2010/289645 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 69 https://doi.org/10.2337/db14-1018 https://doi.org/10.2337/db14-1018 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 70 https://doi.org/10.1210/en.2011-1691 https://doi.org/10.1210/en.2011-1691 NN work_lbjz23isnfbh5bcl4jbmahp6r4 297 71 https://doi.org/10.1210/en.2011-1691 https://doi.org/10.1210/en.2011-1691 NNS work_lbjz23isnfbh5bcl4jbmahp6r4 297 72 https://doi.org/10.1016/j.neubiorev.2008.05.024 https://doi.org/10.1016/j.neubiorev.2008.05.024 ADD work_lbjz23isnfbh5bcl4jbmahp6r4 297 73 https://doi.org/10.1016/j.clinbiochem.2011.11.010 https://doi.org/10.1016/j.clinbiochem.2011.11.010 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 74 https://doi.org/10.1016/j.clinbiochem.2011.11.010 https://doi.org/10.1016/j.clinbiochem.2011.11.010 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 75 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 76 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 77 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 78 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 79 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 80 Popovic Popovic NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 81 et et NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 82   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 297 83 al al NNP work_lbjz23isnfbh5bcl4jbmahp6r4 297 84 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 298 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 298 2 role role NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 298 4 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 5 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 298 6 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 298 7 regulation regulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 298 9 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 10 7239:7 7239:7 CD work_lbjz23isnfbh5bcl4jbmahp6r4 298 11 42 42 CD work_lbjz23isnfbh5bcl4jbmahp6r4 298 12 Aktimur aktimur NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 13   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 14 R r NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 15 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 16 Mete Mete NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 17   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 18 T T NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 19 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 20 Cetinkunar Cetinkunar NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 21   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 22 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 23 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 24 Yaman Yaman NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 25   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 26 M M NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 27 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 28 Beton Beton NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 29   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 30 O o UH work_lbjz23isnfbh5bcl4jbmahp6r4 298 31 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 32 Avci Avci NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 33   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 34 E E NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 35 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 36 Erdem Erdem NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 37   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 38 H H NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 39 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 298 40 Yildirim Yildirim NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 41   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 298 42 K. K. NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 43 Copeptin Copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 298 44 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 45 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 298 46 marker marker NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 47 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 298 48 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 49 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 298 50 decreases decrease VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 298 51 significantly significantly RB work_lbjz23isnfbh5bcl4jbmahp6r4 298 52 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 298 53 early early JJ work_lbjz23isnfbh5bcl4jbmahp6r4 298 54 state state NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 55 after after IN work_lbjz23isnfbh5bcl4jbmahp6r4 298 56 bariatric bariatric JJ work_lbjz23isnfbh5bcl4jbmahp6r4 298 57 surgery surgery NN work_lbjz23isnfbh5bcl4jbmahp6r4 298 58 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 299 1 Endocrine Endocrine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 299 2 Abstracts abstract NNS work_lbjz23isnfbh5bcl4jbmahp6r4 299 3 2016 2016 CD work_lbjz23isnfbh5bcl4jbmahp6r4 299 4 41 41 CD work_lbjz23isnfbh5bcl4jbmahp6r4 299 5 EP806 ep806 NN work_lbjz23isnfbh5bcl4jbmahp6r4 299 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 300 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 300 2 https://doi.org/10.1530/endoabs.41.EP806 https://doi.org/10.1530/endoabs.41.ep806 NN work_lbjz23isnfbh5bcl4jbmahp6r4 300 3 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 300 4 43 43 CD work_lbjz23isnfbh5bcl4jbmahp6r4 300 5 Whitton Whitton NNP work_lbjz23isnfbh5bcl4jbmahp6r4 300 6   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 300 7 PD PD NNP work_lbjz23isnfbh5bcl4jbmahp6r4 300 8 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 300 9 Rodrigues Rodrigues NNP work_lbjz23isnfbh5bcl4jbmahp6r4 300 10   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 300 11 LM LM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 300 12 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 300 13 Hems Hems NNP work_lbjz23isnfbh5bcl4jbmahp6r4 300 14   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 300 15 DA DA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 300 16 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 301 1 Stimulation stimulation NN work_lbjz23isnfbh5bcl4jbmahp6r4 301 2 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 301 3 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 301 4 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 301 5 angiotensin angiotensin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 301 6 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 301 7 oxytocin oxytocin NNS work_lbjz23isnfbh5bcl4jbmahp6r4 301 8 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 301 9 gluconeogenesis gluconeogenesis NN work_lbjz23isnfbh5bcl4jbmahp6r4 301 10 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 301 11 hepatocyte hepatocyte JJ work_lbjz23isnfbh5bcl4jbmahp6r4 301 12 suspensions suspension NNS work_lbjz23isnfbh5bcl4jbmahp6r4 301 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 302 1 Biochemical Biochemical NNP work_lbjz23isnfbh5bcl4jbmahp6r4 302 2 Journal Journal NNP work_lbjz23isnfbh5bcl4jbmahp6r4 302 3 1978 1978 CD work_lbjz23isnfbh5bcl4jbmahp6r4 302 4 176 176 CD work_lbjz23isnfbh5bcl4jbmahp6r4 302 5 893–898 893–898 CD work_lbjz23isnfbh5bcl4jbmahp6r4 302 6 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 303 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 303 2 https://doi https://doi NN work_lbjz23isnfbh5bcl4jbmahp6r4 303 3 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 304 1 org/10.1042 org/10.1042 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 304 2 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 304 3 bj1760893 bj1760893 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 304 4 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 304 5 44 44 CD work_lbjz23isnfbh5bcl4jbmahp6r4 304 6 Keppens Keppens NNP work_lbjz23isnfbh5bcl4jbmahp6r4 304 7   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 304 8 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 304 9 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 304 10 De De NNP work_lbjz23isnfbh5bcl4jbmahp6r4 304 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 304 12 WH WH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 304 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 305 1 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 305 2 nature nature NN work_lbjz23isnfbh5bcl4jbmahp6r4 305 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 305 4 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 305 5 hepatic hepatic JJ work_lbjz23isnfbh5bcl4jbmahp6r4 305 6 receptors receptor NNS work_lbjz23isnfbh5bcl4jbmahp6r4 305 7 involved involve VBN work_lbjz23isnfbh5bcl4jbmahp6r4 305 8 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 305 9 vasopressin vasopressin NN work_lbjz23isnfbh5bcl4jbmahp6r4 305 10 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 305 11 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 305 12 glycogenolysis glycogenolysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 305 13 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 306 1 BBA BBA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 306 2 – – : work_lbjz23isnfbh5bcl4jbmahp6r4 306 3 Series Series NNP work_lbjz23isnfbh5bcl4jbmahp6r4 306 4 General General NNP work_lbjz23isnfbh5bcl4jbmahp6r4 306 5 Subjects Subjects NNP work_lbjz23isnfbh5bcl4jbmahp6r4 306 6 1979 1979 CD work_lbjz23isnfbh5bcl4jbmahp6r4 306 7 588 588 CD work_lbjz23isnfbh5bcl4jbmahp6r4 306 8 63–69 63–69 CD work_lbjz23isnfbh5bcl4jbmahp6r4 306 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 307 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 307 2 https://doi.org/10.1016/0304- https://doi.org/10.1016/0304- NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 3 4165(79)90371 4165(79)90371 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 4 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 307 5 4 4 CD work_lbjz23isnfbh5bcl4jbmahp6r4 307 6 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 307 7 45 45 CD work_lbjz23isnfbh5bcl4jbmahp6r4 307 8 Abu Abu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 9 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 307 10 Basha Basha NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 11   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 307 12 EA EA NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 13 , , , work_lbjz23isnfbh5bcl4jbmahp6r4 307 14 Yibchok Yibchok NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 15 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 307 16 Anun Anun NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 17   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 307 18 S S NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 19 & & CC work_lbjz23isnfbh5bcl4jbmahp6r4 307 20 Hsu Hsu NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 21   _SP work_lbjz23isnfbh5bcl4jbmahp6r4 307 22 WH WH NNP work_lbjz23isnfbh5bcl4jbmahp6r4 307 23 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 308 1 Glucose glucose VB work_lbjz23isnfbh5bcl4jbmahp6r4 308 2 dependency dependency NN work_lbjz23isnfbh5bcl4jbmahp6r4 308 3 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 308 4 arginine arginine NNP work_lbjz23isnfbh5bcl4jbmahp6r4 308 5 vasopressin vasopressin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 308 6 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 308 7 induced induce VBN work_lbjz23isnfbh5bcl4jbmahp6r4 308 8 insulin insulin NN work_lbjz23isnfbh5bcl4jbmahp6r4 308 9 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 308 10 glucagon glucagon NN work_lbjz23isnfbh5bcl4jbmahp6r4 308 11 release release NN work_lbjz23isnfbh5bcl4jbmahp6r4 308 12 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 308 13 the the DT work_lbjz23isnfbh5bcl4jbmahp6r4 308 14 perfused perfuse VBN work_lbjz23isnfbh5bcl4jbmahp6r4 308 15 rat rat NN work_lbjz23isnfbh5bcl4jbmahp6r4 308 16 pancreas pancrea NNS work_lbjz23isnfbh5bcl4jbmahp6r4 308 17 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 309 1 Metabolism metabolism NN work_lbjz23isnfbh5bcl4jbmahp6r4 309 2 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 309 3 Clinical clinical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 309 4 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 309 5 Experimental experimental JJ work_lbjz23isnfbh5bcl4jbmahp6r4 309 6 2002 2002 CD work_lbjz23isnfbh5bcl4jbmahp6r4 309 7 51 51 CD work_lbjz23isnfbh5bcl4jbmahp6r4 309 8 1184–1190 1184–1190 CD work_lbjz23isnfbh5bcl4jbmahp6r4 309 9 . . . work_lbjz23isnfbh5bcl4jbmahp6r4 310 1 ( ( -LRB- work_lbjz23isnfbh5bcl4jbmahp6r4 310 2 doi:10.1053 doi:10.1053 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 3 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 310 4 meta.2002.34052 meta.2002.34052 NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 5 ) ) -RRB- work_lbjz23isnfbh5bcl4jbmahp6r4 310 6 Received receive VBN work_lbjz23isnfbh5bcl4jbmahp6r4 310 7 in in IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 8 final final JJ work_lbjz23isnfbh5bcl4jbmahp6r4 310 9 form form NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 10 10 10 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 11 June June NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 12 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 13 Accepted Accepted NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 14 1 1 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 15 July July NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 16 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 17 Accepted Accepted NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 18 Manuscript Manuscript NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 19 published publish VBD work_lbjz23isnfbh5bcl4jbmahp6r4 310 20 online online RB work_lbjz23isnfbh5bcl4jbmahp6r4 310 21 2 2 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 22 July July NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 23 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 24 This this DT work_lbjz23isnfbh5bcl4jbmahp6r4 310 25 work work NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 26 is be VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 310 27 licensed license VBN work_lbjz23isnfbh5bcl4jbmahp6r4 310 28 under under IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 29 a a DT work_lbjz23isnfbh5bcl4jbmahp6r4 310 30 Creative Creative NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 31 Commons Commons NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 32 Attribution Attribution NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 33 - - HYPH work_lbjz23isnfbh5bcl4jbmahp6r4 310 34 NonCommercial NonCommercial NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 35 4.0 4.0 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 36 International International NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 37 License.https://doi.org/10.1530/EC-20-0197 License.https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 38 https://ec.bioscientifica.com https://ec.bioscientifica.com ADD work_lbjz23isnfbh5bcl4jbmahp6r4 310 39 © © NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 40 2020 2020 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 41 The the DT work_lbjz23isnfbh5bcl4jbmahp6r4 310 42 authors author NNS work_lbjz23isnfbh5bcl4jbmahp6r4 310 43 Published publish VBN work_lbjz23isnfbh5bcl4jbmahp6r4 310 44 by by IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 45 Bioscientifica Bioscientifica NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 46 Ltd Ltd NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 47 Downloaded download VBN work_lbjz23isnfbh5bcl4jbmahp6r4 310 48 from from IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 49 Bioscientifica.com Bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 50 at at IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 51 04/06/2021 04/06/2021 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 52 04:58:20PM 04:58:20PM NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 53 via via IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 54 free free JJ work_lbjz23isnfbh5bcl4jbmahp6r4 310 55 access access NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 56 https://doi.org/10.1042/bj1760893 https://doi.org/10.1042/bj1760893 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 57 https://doi.org/10.1042/bj1760893 https://doi.org/10.1042/bj1760893 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 58 https://doi.org/10.1016/0304-4165(79)90371-4 https://doi.org/10.1016/0304-4165(79)90371-4 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 59 https://doi.org/10.1016/0304-4165(79)90371-4 https://doi.org/10.1016/0304-4165(79)90371-4 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 60 10.1053 10.1053 CD work_lbjz23isnfbh5bcl4jbmahp6r4 310 61 / / SYM work_lbjz23isnfbh5bcl4jbmahp6r4 310 62 meta.2002.34052 meta.2002.34052 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 63 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 64 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 65 https://doi.org/10.1530/EC-20-0197 https://doi.org/10.1530/EC-20-0197 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 66 https://ec.bioscientifica.com https://ec.bioscientifica.com NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 67 Abstract abstract JJ work_lbjz23isnfbh5bcl4jbmahp6r4 310 68 Introduction introduction NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 69 Methods Methods NNPS work_lbjz23isnfbh5bcl4jbmahp6r4 310 70 Study Study NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 71 A a NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 72 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 310 73 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 310 74 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 310 75 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 76 design design NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 77 Study study NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 78 B B NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 79 : : : work_lbjz23isnfbh5bcl4jbmahp6r4 310 80 Patients patient NNS work_lbjz23isnfbh5bcl4jbmahp6r4 310 81 and and CC work_lbjz23isnfbh5bcl4jbmahp6r4 310 82 trial trial NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 83 design design NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 84 Laboratory Laboratory NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 85 analyses analyse VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 310 86 Statistical statistical JJ work_lbjz23isnfbh5bcl4jbmahp6r4 310 87 analysis analysis NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 88 Results Results NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 89 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 90 characteristics characteristic NNS work_lbjz23isnfbh5bcl4jbmahp6r4 310 91 Baseline Baseline NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 92 copeptin copeptin NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 93 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 310 94 Effect Effect NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 95 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 96 IL-1 IL-1 NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 97 receptor receptor NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 98 antagonism antagonism NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 99 on on IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 100 copeptin copeptin NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 101 levels level NNS work_lbjz23isnfbh5bcl4jbmahp6r4 310 102 Discussion Discussion NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 103 Declaration Declaration NNP work_lbjz23isnfbh5bcl4jbmahp6r4 310 104 of of IN work_lbjz23isnfbh5bcl4jbmahp6r4 310 105 interest interest NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 106 Funding fund VBG work_lbjz23isnfbh5bcl4jbmahp6r4 310 107 Financial financial JJ work_lbjz23isnfbh5bcl4jbmahp6r4 310 108 support support NN work_lbjz23isnfbh5bcl4jbmahp6r4 310 109 Acknowledgements acknowledgement VBZ work_lbjz23isnfbh5bcl4jbmahp6r4 310 110 References reference NNS