id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-284370-68o6f7ty	Zhou, Wei	Simultaneous determination of phenolic acids by UPLC–MS/MS in rat plasma and its application in pharmacokinetic study after oral administration of Flos Lonicerae preparations	2013-12-31		.txt	text/plain	4616	193	43	title: Simultaneous determination of phenolic acids by UPLC–MS/MS in rat plasma and its application in pharmacokinetic study after oral administration of Flos Lonicerae preparations In this study, a rapid and selective ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous determination of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, 3,5-dicaffeoylquinic acid and 3,4-dicaffeoylquinic acid was developed in rat plasma. The method was fully validated and applied to the pharmacokinetic study of phenolic acids in rat plasma following oral administration of Flos Lonicerae preparations. This validated UPLC-MS/MS method reported for the first time by us was successfully applied to the pharmacokinetic study of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, 3,5dicaffeoylquinic acid and 3,4-dicaffeoylquinic acid in rat plasma following oral administration of Flos Lonicerae preparations.	./cache/cord-284370-68o6f7ty.txt	./txt/cord-284370-68o6f7ty.txt