id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-303879-3hug5hj3	Cushnie, T.P. Tim	Antimicrobial activity of flavonoids	2005-10-19		.txt	text/plain	7955	450	38	Increasingly, this class of natural products is becoming the subject of anti-infective research, and many groups have isolated and identified the structures of flavonoids possessing antifungal, antiviral and antibacterial activity. Although there have been comparatively few studies into the mechanisms underlying flavonoid antibacterial activity, information from published literature indicates that different compounds within this class of phytochemicals may target different components and functions of the bacterial cell [137] [138] [139] . The cytoplasmic membrane activity detected for quercetin by Mirzoeva and co-workers may represent one of the additional mechanisms of antibacterial action that was suspected to be present among the seven DNA gyrase-inhibiting flavonoid compounds tested by Ohemeng and colleagues [68] . In addition to the structural alteration of weak and moderately active antimicrobial flavonoids, investigation into the mechanisms of action of these compounds is likely to be a productive area of research.	./cache/cord-303879-3hug5hj3.txt	./txt/cord-303879-3hug5hj3.txt