id author title date pages extension mime words sentences flesch summary cache txt cord-001401-f29y8vh5 Nelson, Martha I. Multiyear Persistence of 2 Pandemic A/H1N1 Influenza Virus Lineages in West Africa 2014-07-01 .txt text/plain 2511 121 47 Increased genetic sequencing of African A/H1N1 pandemic influenza viruses during 2009-2013 revealed multiyear persistence of 2 viral lineages within West Africa, raising questions about the roles of reduced air traffic and the asynchrony of seasonal influenza epidemics among West African countries in the evolution of independent lineages. Increased genetic sequencing of African A/H1N1 pandemic influenza viruses during 2009-2013 revealed multiyear persistence of 2 viral lineages within West Africa, raising questions about the roles of reduced air traffic and the asynchrony of seasonal influenza epidemics among West African countries in the evolution of independent lineages. To elucidate the evolution of influenza viruses in Africa, we conducted a large-scale phylogenetic analysis of global pH1N1 influenza virus diversity during 2009-2013, including 299 pH1N1 HA sequences collected in 18 African countries. Our analysis identified 2 well-supported clades of pH1N1 viruses that each persisted for >1.5 years in West Africa, highlighting the need to further understand the ecology and evolution of IAVs in this understudied and relatively geographically isolated region. ./cache/cord-001401-f29y8vh5.txt ./txt/cord-001401-f29y8vh5.txt