id author title date pages extension mime words sentences flesch summary cache txt cord-020694-zoy49483 Baig, Ulfat Geriatric infections: Decreased immunity or evolved opportunists? 2020-04-10 .txt text/plain 3215 171 47 In order to compare the age specific incidence of opportunistic versus non-opportunistic infections, we selected pathogens that are sufficiently common globally, for whom there is good background epidemiological information including whether and with what frequency they inhabit the host body under normal conditions, whether a long-term carrier state is known, and whether they confer long-term immunity. We searched PubMed and Google Scholar for individual published reports giving age-class-specific incidence, in addition to available online data from Centers for Disease Control Bureau of Statistics. In the other pattern followed by 8 species and 12 pooled datasets, there was a significant negative trend in 6 with a 50% to 95% decrease in incidence between the 20 and over-60 age groups. The prediction specific to the declining immunity hypothesis that the incidence of externally acquired infections should also increase with age failed to obtain generalized support in epidemiological data. ./cache/cord-020694-zoy49483.txt ./txt/cord-020694-zoy49483.txt