id author title date pages extension mime words sentences flesch summary cache txt cord-029015-rn62sbfm Guyonnet, Sophie The INSPIRE Bio-Resource Research Platform for Healthy Aging and Geroscience: Focus on the Human Translational Research Cohort (The INSPIRE-T Cohort) 2020-07-10 .txt text/plain 6088 269 44 The INSPIRE Human Translational Cohort (INSPIRE-T cohort) will recruit about 1000 individuals of several chronological ages (from 20 years to 100+) and functional capacity levels (from robust to frail, and even disabled) with baseline and follow-up biological, clinical, imaging and digital data over 10 years. The remote monitoring of intrinsic capacity will last the whole length of this research study, i.e., up to ten years Other examinations are proposed to a limited number of participants (all age ranges and functional status) in a volunteer basis: Dual energy X-ray absorptiometry (DXA) for body composition assessment; Whole body and brain magnetic resonance (MRI); cardiorespiratory fitness (maximum oxygen consumption (V02 max) with blood sampling before and after the effort, and maximal aerobic power), and isokinetic muscle strength. The INSPIRE-T cohort will gather clinical, biological (including imaging), and digital data for subjects of several chronological ages and functional capacity status regularly followed over up to 10 years. ./cache/cord-029015-rn62sbfm.txt ./txt/cord-029015-rn62sbfm.txt