id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294180-t5bncpo4	Neto, Leônidas Oliveira	Aging and Coronavirus: Exploring Complementary Therapies to Avoid Inflammatory Overload	2020-06-26		.txt	text/plain	3499	166	38	It is interesting to highlight that both aging and chronic diseases are linked to an increase in levels of systemic inflammation, which could explain a potential common pathway between these factors and COVID-19. In this context, lifestyle and nutraceuticals arise as important prophylactic interventions to reduce the burden of baseline inflammation in older adults and consequently improve quality of life, mobility, cognition, mood, and metabolic and immune balances, especially during the pandemic. Vitamin D, or more specifically, 25hydroxyvitamin D [25 (OH) D], is an anti-inflammatory nutrient (41) , and reduces the activation of the renin-angiotensin system, preventing hypertension (42), besides its importance to bone and muscle, an inverse relationship is also observed between its levels and mortality risk in old adults (43) . Furthermore, reducing sedentary behavior and engaging in exercise may increasing the production of systemic anti-inflammatory cytokines and help to combat inflammation (63, 64) by increasing innate immune function (65) and decreasing the chronic inflammation related to various diseases (66) .	./cache/cord-294180-t5bncpo4.txt	./txt/cord-294180-t5bncpo4.txt