id author title date pages extension mime words sentences flesch summary cache txt cord-305743-rnfn6opa Anton, Stephen D. Innovations in Geroscience to enhance mobility in older adults 2020-10-22 .txt text/plain 15986 786 40 Aging is the primary risk factor for functional decline; thus, understanding and preventing disability among older adults has emerged as an important public health challenge of the 21st century. Given the aging US population, the disproportionately high prevalence of the metabolic syndrome in older adults is a significant public health concern, as it substantially increases the risk for cardiovascular disease J o u r n a l P r e -p r o o f Journal Pre-proof (CVD) [27] [28] [29] [30] and is associated with increased all-cause mortality, disability, CVD mortality, myocardial infarction, and stroke [31] . Age-related life changes that increase susceptibility to social isolation and loneliness includes changes in health status limiting functioning and mobility; changes in family structure (divorce, childless); death of friends, family members, and spouse; auditory and visual changes reducing the ability to communicate and interact; and resource reductions including healthcare access and quality of care [135] . ./cache/cord-305743-rnfn6opa.txt ./txt/cord-305743-rnfn6opa.txt