id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-309161-ceahghs1	Epel, Elissa S.	The geroscience agenda: What does stress have to do with it?	2020-09-28		.txt	text/plain	7754	447	43	While there are myriad individual patterns of exposures, traumatic stress or material deprivation have larger effects early in life than when they occur at later periods; Early life adversity is predictive of a range of poor outcomes, including poor mental health, health behaviors, biomarkers of aging, and earlier disease onset (Deighton et al., 2018; Hughes et al., 2017) although plasticity is still possible (McEwen & Morrison, 2013) . Several of these basic mechanisms in immune cells have been associated with aspects of social stress, including systemic inflammation and shorter telomeres (Epel et al., 2004; Kiecolt-Glaser et al., 2011; Miller et al., 2008) poor mitochondrial function (Picard et al., 2018) , and accelerated epigenetic aging (Park et al., 2019; Wolf et al., 2018) . Stress resilience depends in part on the pre-existing level of reserve capacity, the positive protective factors of an organism, as well as the immediate adaptive psychological response to stressors (cognitive appraisals).	./cache/cord-309161-ceahghs1.txt	./txt/cord-309161-ceahghs1.txt