id	sid	tid	token	lemma	pos
cord-309556-xv3413k1	1	1	key	key	JJ
cord-309556-xv3413k1	2	1	:	:	:
cord-309556-xv3413k1	2	2	cord-309556-xv3413k1	cord-309556-xv3413k1	VBN
cord-309556-xv3413k1	2	3	authors	author	NNS
cord-309556-xv3413k1	2	4	:	:	:
cord-309556-xv3413k1	2	5	Chow	Chow	NNP
cord-309556-xv3413k1	2	6	,	,	,
cord-309556-xv3413k1	2	7	Ryan	Ryan	NNP
cord-309556-xv3413k1	2	8	D.	D.	NNP
cord-309556-xv3413k1	2	9	;	;	:
cord-309556-xv3413k1	2	10	Chen	Chen	NNP
cord-309556-xv3413k1	2	11	,	,	,
cord-309556-xv3413k1	2	12	Sidi	Sidi	NNP
cord-309556-xv3413k1	2	13	title	title	NN
cord-309556-xv3413k1	2	14	:	:	:
cord-309556-xv3413k1	2	15	The	the	DT
cord-309556-xv3413k1	2	16	aging	age	VBG
cord-309556-xv3413k1	2	17	transcriptome	transcriptome	NN
cord-309556-xv3413k1	2	18	and	and	CC
cord-309556-xv3413k1	2	19	cellular	cellular	JJ
cord-309556-xv3413k1	2	20	landscape	landscape	NN
cord-309556-xv3413k1	2	21	of	of	IN
cord-309556-xv3413k1	2	22	the	the	DT
cord-309556-xv3413k1	2	23	human	human	JJ
cord-309556-xv3413k1	2	24	lung	lung	NN
cord-309556-xv3413k1	2	25	in	in	IN
cord-309556-xv3413k1	2	26	relation	relation	NN
cord-309556-xv3413k1	2	27	to	to	IN
cord-309556-xv3413k1	2	28	SARS	SARS	NNP
cord-309556-xv3413k1	2	29	-	-	HYPH
cord-309556-xv3413k1	2	30	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	2	31	date	date	NN
cord-309556-xv3413k1	2	32	:	:	:
cord-309556-xv3413k1	2	33	2020	2020	CD
cord-309556-xv3413k1	2	34	-	-	HYPH
cord-309556-xv3413k1	2	35	04	04	CD
cord-309556-xv3413k1	2	36	-	-	SYM
cord-309556-xv3413k1	2	37	15	15	CD
cord-309556-xv3413k1	2	38	journal	journal	NN
cord-309556-xv3413k1	2	39	:	:	:
cord-309556-xv3413k1	3	1	bioRxiv	biorxiv	IN
cord-309556-xv3413k1	3	2	DOI	DOI	NNP
cord-309556-xv3413k1	3	3	:	:	:
cord-309556-xv3413k1	4	1	10.1101/2020.04.07.030684	10.1101/2020.04.07.030684	NNP
cord-309556-xv3413k1	5	1	sha	sha	NNP
cord-309556-xv3413k1	5	2	:	:	:
cord-309556-xv3413k1	5	3	56816e072e2af57957c7c6dcbbccd714463004bb	56816e072e2af57957c7c6dcbbccd714463004bb	NNP
cord-309556-xv3413k1	5	4	doc_id	doc_id	CD
cord-309556-xv3413k1	5	5	:	:	:
cord-309556-xv3413k1	5	6	309556	309556	CD
cord-309556-xv3413k1	5	7	cord_uid	cord_uid	NNS
cord-309556-xv3413k1	5	8	:	:	:
cord-309556-xv3413k1	6	1	xv3413k1	xv3413k1	XX
cord-309556-xv3413k1	7	1	Since	since	IN
cord-309556-xv3413k1	7	2	the	the	DT
cord-309556-xv3413k1	7	3	emergence	emergence	NN
cord-309556-xv3413k1	7	4	of	of	IN
cord-309556-xv3413k1	7	5	SARS	SARS	NNP
cord-309556-xv3413k1	7	6	-	-	HYPH
cord-309556-xv3413k1	7	7	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	7	8	in	in	IN
cord-309556-xv3413k1	7	9	December	December	NNP
cord-309556-xv3413k1	7	10	2019	2019	CD
cord-309556-xv3413k1	7	11	,	,	,
cord-309556-xv3413k1	7	12	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	7	13	Disease-2019	Disease-2019	NNP
cord-309556-xv3413k1	7	14	(	(	-LRB-
cord-309556-xv3413k1	7	15	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	7	16	)	)	-RRB-
cord-309556-xv3413k1	7	17	has	have	VBZ
cord-309556-xv3413k1	7	18	rapidly	rapidly	RB
cord-309556-xv3413k1	7	19	spread	spread	VBN
cord-309556-xv3413k1	7	20	across	across	IN
cord-309556-xv3413k1	7	21	the	the	DT
cord-309556-xv3413k1	7	22	globe	globe	NN
cord-309556-xv3413k1	7	23	.	.	.
cord-309556-xv3413k1	8	1	Epidemiologic	epidemiologic	JJ
cord-309556-xv3413k1	8	2	studies	study	NNS
cord-309556-xv3413k1	8	3	have	have	VBP
cord-309556-xv3413k1	8	4	demonstrated	demonstrate	VBN
cord-309556-xv3413k1	8	5	that	that	IN
cord-309556-xv3413k1	8	6	age	age	NN
cord-309556-xv3413k1	8	7	is	be	VBZ
cord-309556-xv3413k1	8	8	one	one	CD
cord-309556-xv3413k1	8	9	of	of	IN
cord-309556-xv3413k1	8	10	the	the	DT
cord-309556-xv3413k1	8	11	strongest	strong	JJS
cord-309556-xv3413k1	8	12	risk	risk	NN
cord-309556-xv3413k1	8	13	factors	factor	NNS
cord-309556-xv3413k1	8	14	influencing	influence	VBG
cord-309556-xv3413k1	8	15	the	the	DT
cord-309556-xv3413k1	8	16	morbidity	morbidity	NN
cord-309556-xv3413k1	8	17	and	and	CC
cord-309556-xv3413k1	8	18	mortality	mortality	NN
cord-309556-xv3413k1	8	19	of	of	IN
cord-309556-xv3413k1	8	20	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	8	21	.	.	.
cord-309556-xv3413k1	9	1	Here	here	RB
cord-309556-xv3413k1	9	2	,	,	,
cord-309556-xv3413k1	9	3	we	-PRON-	PRP
cord-309556-xv3413k1	9	4	interrogate	interrogate	VBP
cord-309556-xv3413k1	9	5	the	the	DT
cord-309556-xv3413k1	9	6	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	9	7	features	feature	NNS
cord-309556-xv3413k1	9	8	and	and	CC
cord-309556-xv3413k1	9	9	cellular	cellular	JJ
cord-309556-xv3413k1	9	10	landscapes	landscape	NNS
cord-309556-xv3413k1	9	11	of	of	IN
cord-309556-xv3413k1	9	12	the	the	DT
cord-309556-xv3413k1	9	13	aging	age	VBG
cord-309556-xv3413k1	9	14	human	human	JJ
cord-309556-xv3413k1	9	15	lung	lung	NN
cord-309556-xv3413k1	9	16	through	through	IN
cord-309556-xv3413k1	9	17	integrative	integrative	JJ
cord-309556-xv3413k1	9	18	analysis	analysis	NN
cord-309556-xv3413k1	9	19	of	of	IN
cord-309556-xv3413k1	9	20	bulk	bulk	JJ
cord-309556-xv3413k1	9	21	and	and	CC
cord-309556-xv3413k1	9	22	single	single	JJ
cord-309556-xv3413k1	9	23	-	-	HYPH
cord-309556-xv3413k1	9	24	cell	cell	NN
cord-309556-xv3413k1	9	25	transcriptomics	transcriptomic	NNS
cord-309556-xv3413k1	9	26	.	.	.
cord-309556-xv3413k1	10	1	By	by	IN
cord-309556-xv3413k1	10	2	intersecting	intersect	VBG
cord-309556-xv3413k1	10	3	these	these	DT
cord-309556-xv3413k1	10	4	age	age	NN
cord-309556-xv3413k1	10	5	-	-	HYPH
cord-309556-xv3413k1	10	6	associated	associate	VBN
cord-309556-xv3413k1	10	7	changes	change	NNS
cord-309556-xv3413k1	10	8	with	with	IN
cord-309556-xv3413k1	10	9	experimental	experimental	JJ
cord-309556-xv3413k1	10	10	data	datum	NNS
cord-309556-xv3413k1	10	11	on	on	IN
cord-309556-xv3413k1	10	12	host	host	NN
cord-309556-xv3413k1	10	13	interactions	interaction	NNS
cord-309556-xv3413k1	10	14	between	between	IN
cord-309556-xv3413k1	10	15	SARS	SARS	NNP
cord-309556-xv3413k1	10	16	-	-	HYPH
cord-309556-xv3413k1	10	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	10	18	or	or	CC
cord-309556-xv3413k1	10	19	its	-PRON-	PRP$
cord-309556-xv3413k1	10	20	relative	relative	JJ
cord-309556-xv3413k1	10	21	SARS	SARS	NNP
cord-309556-xv3413k1	10	22	-	-	HYPH
cord-309556-xv3413k1	10	23	CoV	CoV	NNP
cord-309556-xv3413k1	10	24	,	,	,
cord-309556-xv3413k1	10	25	we	-PRON-	PRP
cord-309556-xv3413k1	10	26	identify	identify	VBP
cord-309556-xv3413k1	10	27	several	several	JJ
cord-309556-xv3413k1	10	28	age	age	NN
cord-309556-xv3413k1	10	29	-	-	HYPH
cord-309556-xv3413k1	10	30	associated	associate	VBN
cord-309556-xv3413k1	10	31	factors	factor	NNS
cord-309556-xv3413k1	10	32	that	that	WDT
cord-309556-xv3413k1	10	33	may	may	MD
cord-309556-xv3413k1	10	34	contribute	contribute	VB
cord-309556-xv3413k1	10	35	to	to	IN
cord-309556-xv3413k1	10	36	the	the	DT
cord-309556-xv3413k1	10	37	heightened	heightened	JJ
cord-309556-xv3413k1	10	38	severity	severity	NN
cord-309556-xv3413k1	10	39	of	of	IN
cord-309556-xv3413k1	10	40	COVID-19	covid-19	CD
cord-309556-xv3413k1	10	41	in	in	IN
cord-309556-xv3413k1	10	42	older	old	JJR
cord-309556-xv3413k1	10	43	populations	population	NNS
cord-309556-xv3413k1	10	44	.	.	.
cord-309556-xv3413k1	11	1	We	-PRON-	PRP
cord-309556-xv3413k1	11	2	observed	observe	VBD
cord-309556-xv3413k1	11	3	that	that	IN
cord-309556-xv3413k1	11	4	age	age	NN
cord-309556-xv3413k1	11	5	-	-	HYPH
cord-309556-xv3413k1	11	6	associated	associate	VBN
cord-309556-xv3413k1	11	7	gene	gene	NN
cord-309556-xv3413k1	11	8	expression	expression	NN
cord-309556-xv3413k1	11	9	and	and	CC
cord-309556-xv3413k1	11	10	cell	cell	NN
cord-309556-xv3413k1	11	11	populations	population	NNS
cord-309556-xv3413k1	11	12	are	be	VBP
cord-309556-xv3413k1	11	13	significantly	significantly	RB
cord-309556-xv3413k1	11	14	linked	link	VBN
cord-309556-xv3413k1	11	15	to	to	IN
cord-309556-xv3413k1	11	16	the	the	DT
cord-309556-xv3413k1	11	17	heightened	heightened	JJ
cord-309556-xv3413k1	11	18	severity	severity	NN
cord-309556-xv3413k1	11	19	of	of	IN
cord-309556-xv3413k1	11	20	COVID-19	covid-19	CD
cord-309556-xv3413k1	11	21	in	in	IN
cord-309556-xv3413k1	11	22	older	old	JJR
cord-309556-xv3413k1	11	23	populations	population	NNS
cord-309556-xv3413k1	11	24	.	.	.
cord-309556-xv3413k1	12	1	The	the	DT
cord-309556-xv3413k1	12	2	aging	age	VBG
cord-309556-xv3413k1	12	3	lung	lung	NN
cord-309556-xv3413k1	12	4	is	be	VBZ
cord-309556-xv3413k1	12	5	characterized	characterize	VBN
cord-309556-xv3413k1	12	6	by	by	IN
cord-309556-xv3413k1	12	7	increased	increase	VBN
cord-309556-xv3413k1	12	8	vascular	vascular	JJ
cord-309556-xv3413k1	12	9	smooth	smooth	JJ
cord-309556-xv3413k1	12	10	muscle	muscle	NN
cord-309556-xv3413k1	12	11	contraction	contraction	NN
cord-309556-xv3413k1	12	12	,	,	,
cord-309556-xv3413k1	12	13	reduced	reduce	VBN
cord-309556-xv3413k1	12	14	mitochondrial	mitochondrial	JJ
cord-309556-xv3413k1	12	15	activity	activity	NN
cord-309556-xv3413k1	12	16	,	,	,
cord-309556-xv3413k1	12	17	and	and	CC
cord-309556-xv3413k1	12	18	decreased	decrease	VBD
cord-309556-xv3413k1	12	19	lipid	lipid	NN
cord-309556-xv3413k1	12	20	metabolism	metabolism	NN
cord-309556-xv3413k1	12	21	.	.	.
cord-309556-xv3413k1	13	1	Lung	lung	NN
cord-309556-xv3413k1	13	2	epithelial	epithelial	JJ
cord-309556-xv3413k1	13	3	cells	cell	NNS
cord-309556-xv3413k1	13	4	,	,	,
cord-309556-xv3413k1	13	5	macrophages	macrophage	NNS
cord-309556-xv3413k1	13	6	,	,	,
cord-309556-xv3413k1	13	7	and	and	CC
cord-309556-xv3413k1	13	8	Th1	th1	NN
cord-309556-xv3413k1	13	9	cells	cell	NNS
cord-309556-xv3413k1	13	10	decrease	decrease	VBP
cord-309556-xv3413k1	13	11	in	in	IN
cord-309556-xv3413k1	13	12	abundance	abundance	NN
cord-309556-xv3413k1	13	13	with	with	IN
cord-309556-xv3413k1	13	14	age	age	NN
cord-309556-xv3413k1	13	15	,	,	,
cord-309556-xv3413k1	13	16	whereas	whereas	IN
cord-309556-xv3413k1	13	17	fibroblasts	fibroblast	NNS
cord-309556-xv3413k1	13	18	,	,	,
cord-309556-xv3413k1	13	19	pericytes	pericyte	NNS
cord-309556-xv3413k1	13	20	and	and	CC
cord-309556-xv3413k1	13	21	CD4	CD4	NNP
cord-309556-xv3413k1	13	22	+	+	CC
cord-309556-xv3413k1	13	23	Tcm	Tcm	NNP
cord-309556-xv3413k1	13	24	cells	cell	NNS
cord-309556-xv3413k1	13	25	increase	increase	VBP
cord-309556-xv3413k1	13	26	in	in	IN
cord-309556-xv3413k1	13	27	abundance	abundance	NN
cord-309556-xv3413k1	13	28	with	with	IN
cord-309556-xv3413k1	13	29	age	age	NN
cord-309556-xv3413k1	13	30	.	.	.
cord-309556-xv3413k1	14	1	Several	several	JJ
cord-309556-xv3413k1	14	2	age	age	NN
cord-309556-xv3413k1	14	3	-	-	HYPH
cord-309556-xv3413k1	14	4	associated	associate	VBN
cord-309556-xv3413k1	14	5	genes	gene	NNS
cord-309556-xv3413k1	14	6	have	have	VBP
cord-309556-xv3413k1	14	7	functional	functional	JJ
cord-309556-xv3413k1	14	8	effects	effect	NNS
cord-309556-xv3413k1	14	9	on	on	IN
cord-309556-xv3413k1	14	10	SARS	SARS	NNP
cord-309556-xv3413k1	14	11	-	-	HYPH
cord-309556-xv3413k1	14	12	CoV	CoV	NNP
cord-309556-xv3413k1	14	13	replication	replication	NN
cord-309556-xv3413k1	14	14	,	,	,
cord-309556-xv3413k1	14	15	and	and	CC
cord-309556-xv3413k1	14	16	directly	directly	RB
cord-309556-xv3413k1	14	17	interact	interact	VB
cord-309556-xv3413k1	14	18	with	with	IN
cord-309556-xv3413k1	14	19	the	the	DT
cord-309556-xv3413k1	14	20	SARS	SARS	NNP
cord-309556-xv3413k1	14	21	-	-	HYPH
cord-309556-xv3413k1	14	22	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	14	23	proteome	proteome	NN
cord-309556-xv3413k1	14	24	.	.	.
cord-309556-xv3413k1	15	1	Interestingly	interestingly	RB
cord-309556-xv3413k1	15	2	,	,	,
cord-309556-xv3413k1	15	3	age	age	NN
cord-309556-xv3413k1	15	4	-	-	HYPH
cord-309556-xv3413k1	15	5	associated	associate	VBN
cord-309556-xv3413k1	15	6	genes	gene	NNS
cord-309556-xv3413k1	15	7	are	be	VBP
cord-309556-xv3413k1	15	8	heavily	heavily	RB
cord-309556-xv3413k1	15	9	enriched	enrich	VBN
cord-309556-xv3413k1	15	10	among	among	IN
cord-309556-xv3413k1	15	11	those	those	DT
cord-309556-xv3413k1	15	12	induced	induce	VBN
cord-309556-xv3413k1	15	13	or	or	CC
cord-309556-xv3413k1	15	14	suppressed	suppress	VBN
cord-309556-xv3413k1	15	15	by	by	IN
cord-309556-xv3413k1	15	16	SARS	SARS	NNP
cord-309556-xv3413k1	15	17	-	-	HYPH
cord-309556-xv3413k1	15	18	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	15	19	infection	infection	NN
cord-309556-xv3413k1	15	20	.	.	.
cord-309556-xv3413k1	16	1	These	these	DT
cord-309556-xv3413k1	16	2	analyses	analysis	NNS
cord-309556-xv3413k1	16	3	illuminate	illuminate	VBP
cord-309556-xv3413k1	16	4	potential	potential	JJ
cord-309556-xv3413k1	16	5	avenues	avenue	NNS
cord-309556-xv3413k1	16	6	for	for	IN
cord-309556-xv3413k1	16	7	further	further	JJ
cord-309556-xv3413k1	16	8	studies	study	NNS
cord-309556-xv3413k1	16	9	on	on	IN
cord-309556-xv3413k1	16	10	the	the	DT
cord-309556-xv3413k1	16	11	relationship	relationship	NN
cord-309556-xv3413k1	16	12	between	between	IN
cord-309556-xv3413k1	16	13	the	the	DT
cord-309556-xv3413k1	16	14	aging	age	VBG
cord-309556-xv3413k1	16	15	lung	lung	NN
cord-309556-xv3413k1	16	16	and	and	CC
cord-309556-xv3413k1	16	17	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	16	18	pathogenesis	pathogenesis	NN
cord-309556-xv3413k1	16	19	,	,	,
cord-309556-xv3413k1	16	20	which	which	WDT
cord-309556-xv3413k1	16	21	may	may	MD
cord-309556-xv3413k1	16	22	inform	inform	VB
cord-309556-xv3413k1	16	23	strategies	strategy	NNS
cord-309556-xv3413k1	16	24	to	to	IN
cord-309556-xv3413k1	16	25	more	more	RBR
cord-309556-xv3413k1	16	26	effectively	effectively	RB
cord-309556-xv3413k1	16	27	treat	treat	VB
cord-309556-xv3413k1	16	28	this	this	DT
cord-309556-xv3413k1	16	29	disease	disease	NN
cord-309556-xv3413k1	16	30	.	.	.
cord-309556-xv3413k1	17	1	these	these	DT
cord-309556-xv3413k1	17	2	data	datum	NNS
cord-309556-xv3413k1	17	3	indicate	indicate	VBP
cord-309556-xv3413k1	17	4	that	that	IN
cord-309556-xv3413k1	17	5	differential	differential	JJ
cord-309556-xv3413k1	17	6	expression	expression	NN
cord-309556-xv3413k1	17	7	of	of	IN
cord-309556-xv3413k1	17	8	SARS	SARS	NNP
cord-309556-xv3413k1	17	9	-	-	HYPH
cord-309556-xv3413k1	17	10	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	17	11	host	host	NN
cord-309556-xv3413k1	17	12	entry	entry	NN
cord-309556-xv3413k1	17	13	factors	factor	NNS
cord-309556-xv3413k1	17	14	alone	alone	RB
cord-309556-xv3413k1	17	15	is	be	VBZ
cord-309556-xv3413k1	17	16	unlikely	unlikely	JJ
cord-309556-xv3413k1	17	17	to	to	TO
cord-309556-xv3413k1	17	18	explain	explain	VB
cord-309556-xv3413k1	17	19	the	the	DT
cord-309556-xv3413k1	17	20	relationship	relationship	NN
cord-309556-xv3413k1	17	21	between	between	IN
cord-309556-xv3413k1	17	22	age	age	NN
cord-309556-xv3413k1	17	23	and	and	CC
cord-309556-xv3413k1	17	24	severity	severity	NN
cord-309556-xv3413k1	17	25	of	of	IN
cord-309556-xv3413k1	17	26	COVID-19	covid-19	JJ
cord-309556-xv3413k1	17	27	illness	illness	NN
cord-309556-xv3413k1	17	28	.	.	.
cord-309556-xv3413k1	18	1	To	to	TO
cord-309556-xv3413k1	18	2	discern	discern	VB
cord-309556-xv3413k1	18	3	the	the	DT
cord-309556-xv3413k1	18	4	host	host	NN
cord-309556-xv3413k1	18	5	cell	cell	NN
cord-309556-xv3413k1	18	6	types	type	NNS
cord-309556-xv3413k1	18	7	involved	involve	VBN
cord-309556-xv3413k1	18	8	in	in	IN
cord-309556-xv3413k1	18	9	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	18	10	entry	entry	NN
cord-309556-xv3413k1	18	11	,	,	,
cord-309556-xv3413k1	18	12	we	-PRON-	PRP
cord-309556-xv3413k1	18	13	turned	turn	VBD
cord-309556-xv3413k1	18	14	to	to	IN
cord-309556-xv3413k1	18	15	a	a	DT
cord-309556-xv3413k1	18	16	single	single	JJ
cord-309556-xv3413k1	18	17	cell	cell	NN
cord-309556-xv3413k1	18	18	RNA	rna	NN
cord-309556-xv3413k1	18	19	-	-	HYPH
cord-309556-xv3413k1	18	20	seq	seq	NNP
cord-309556-xv3413k1	18	21	(	(	-LRB-
cord-309556-xv3413k1	18	22	scRNA	scRNA	NNP
cord-309556-xv3413k1	18	23	-	-	HYPH
cord-309556-xv3413k1	18	24	seq	seq	NN
cord-309556-xv3413k1	18	25	)	)	-RRB-
cord-309556-xv3413k1	18	26	dataset	dataset	NN
cord-309556-xv3413k1	18	27	of	of	IN
cord-309556-xv3413k1	18	28	57,020	57,020	CD
cord-309556-xv3413k1	18	29	human	human	JJ
cord-309556-xv3413k1	18	30	lung	lung	NN
cord-309556-xv3413k1	18	31	cells	cell	NNS
cord-309556-xv3413k1	18	32	from	from	IN
cord-309556-xv3413k1	18	33	the	the	DT
cord-309556-xv3413k1	18	34	Tissue	Tissue	NNP
cord-309556-xv3413k1	18	35	Stability	Stability	NNP
cord-309556-xv3413k1	18	36	Cell	Cell	NNP
cord-309556-xv3413k1	18	37	Atlas	Atlas	NNP
cord-309556-xv3413k1	18	38	19	19	CD
cord-309556-xv3413k1	18	39	.	.	.
cord-309556-xv3413k1	19	1	In	in	IN
cord-309556-xv3413k1	19	2	agreement	agreement	NN
cord-309556-xv3413k1	19	3	with	with	IN
cord-309556-xv3413k1	19	4	prior	prior	JJ
cord-309556-xv3413k1	19	5	reports	report	NNS
cord-309556-xv3413k1	19	6	,	,	,
cord-309556-xv3413k1	19	7	analysis	analysis	NN
cord-309556-xv3413k1	19	8	of	of	IN
cord-309556-xv3413k1	19	9	the	the	DT
cord-309556-xv3413k1	19	10	single	single	JJ
cord-309556-xv3413k1	19	11	cell	cell	NN
cord-309556-xv3413k1	19	12	lung	lung	NN
cord-309556-xv3413k1	19	13	transcriptomes	transcriptomes	NNP
cord-309556-xv3413k1	19	14	revealed	reveal	VBD
cord-309556-xv3413k1	19	15	that	that	IN
cord-309556-xv3413k1	19	16	alveolar	alveolar	NN
cord-309556-xv3413k1	19	17	type	type	NN
cord-309556-xv3413k1	19	18	2	2	CD
cord-309556-xv3413k1	19	19	(	(	-LRB-
cord-309556-xv3413k1	19	20	AT2	at2	NN
cord-309556-xv3413k1	19	21	)	)	-RRB-
cord-309556-xv3413k1	19	22	cells	cell	NNS
cord-309556-xv3413k1	19	23	were	be	VBD
cord-309556-xv3413k1	19	24	comparatively	comparatively	RB
cord-309556-xv3413k1	19	25	enriched	enrich	VBN
cord-309556-xv3413k1	19	26	in	in	IN
cord-309556-xv3413k1	19	27	ACE2	ACE2	NNP
cord-309556-xv3413k1	19	28	and	and	CC
cord-309556-xv3413k1	19	29	TMPRSS2-expressing	tmprss2-expresse	VBG
cord-309556-xv3413k1	19	30	cells	cell	NNS
cord-309556-xv3413k1	19	31	20	20	CD
cord-309556-xv3413k1	19	32	,	,	,
cord-309556-xv3413k1	19	33	21	21	CD
cord-309556-xv3413k1	19	34	(	(	-LRB-
cord-309556-xv3413k1	19	35	Supplementary	Supplementary	NNP
cord-309556-xv3413k1	19	36	Figure	Figure	NNP
cord-309556-xv3413k1	19	37	3a	3a	NN
cord-309556-xv3413k1	19	38	-	-	HYPH
cord-309556-xv3413k1	19	39	b	b	NN
cord-309556-xv3413k1	19	40	)	)	-RRB-
cord-309556-xv3413k1	19	41	.	.	.
cord-309556-xv3413k1	20	1	However	however	RB
cord-309556-xv3413k1	20	2	,	,	,
cord-309556-xv3413k1	20	3	ACE2-expressing	ace2-expressing	NN
cord-309556-xv3413k1	20	4	cells	cell	NNS
cord-309556-xv3413k1	20	5	represented	represent	VBN
cord-309556-xv3413k1	20	6	only	only	RB
cord-309556-xv3413k1	20	7	1.69	1.69	CD
cord-309556-xv3413k1	20	8	%	%	NN
cord-309556-xv3413k1	20	9	of	of	IN
cord-309556-xv3413k1	20	10	all	all	DT
cord-309556-xv3413k1	20	11	AT2	at2	NN
cord-309556-xv3413k1	20	12	cells	cell	NNS
cord-309556-xv3413k1	20	13	,	,	,
cord-309556-xv3413k1	20	14	while	while	IN
cord-309556-xv3413k1	20	15	47.52	47.52	CD
cord-309556-xv3413k1	20	16	%	%	NN
cord-309556-xv3413k1	20	17	of	of	IN
cord-309556-xv3413k1	20	18	AT2	at2	NN
cord-309556-xv3413k1	20	19	cells	cell	NNS
cord-309556-xv3413k1	20	20	expressed	express	VBD
cord-309556-xv3413k1	20	21	TMPRSS2	TMPRSS2	NNP
cord-309556-xv3413k1	20	22	.	.	.
cord-309556-xv3413k1	21	1	Alveolar	alveolar	NN
cord-309556-xv3413k1	21	2	type	type	NN
cord-309556-xv3413k1	21	3	1	1	CD
cord-309556-xv3413k1	21	4	(	(	-LRB-
cord-309556-xv3413k1	21	5	AT1	at1	NN
cord-309556-xv3413k1	21	6	)	)	-RRB-
cord-309556-xv3413k1	21	7	cells	cell	NNS
cord-309556-xv3413k1	21	8	also	also	RB
cord-309556-xv3413k1	21	9	showed	show	VBD
cord-309556-xv3413k1	21	10	detectable	detectable	JJ
cord-309556-xv3413k1	21	11	expression	expression	NN
cord-309556-xv3413k1	21	12	of	of	IN
cord-309556-xv3413k1	21	13	ACE2	ACE2	NNP
cord-309556-xv3413k1	21	14	and	and	CC
cord-309556-xv3413k1	21	15	TMPRSS2	TMPRSS2	NNP
cord-309556-xv3413k1	21	16	,	,	,
cord-309556-xv3413k1	21	17	but	but	CC
cord-309556-xv3413k1	21	18	at	at	IN
cord-309556-xv3413k1	21	19	lower	low	JJR
cord-309556-xv3413k1	21	20	frequencies	frequency	NNS
cord-309556-xv3413k1	21	21	(	(	-LRB-
cord-309556-xv3413k1	21	22	0.39	0.39	CD
cord-309556-xv3413k1	21	23	%	%	NN
cord-309556-xv3413k1	21	24	and	and	CC
cord-309556-xv3413k1	21	25	26.70	26.70	CD
cord-309556-xv3413k1	21	26	%	%	NN
cord-309556-xv3413k1	21	27	)	)	-RRB-
cord-309556-xv3413k1	21	28	.	.	.
cord-309556-xv3413k1	22	1	CTSL	CTSL	NNP
cord-309556-xv3413k1	22	2	expression	expression	NN
cord-309556-xv3413k1	22	3	could	could	MD
cord-309556-xv3413k1	22	4	be	be	VB
cord-309556-xv3413k1	22	5	broadly	broadly	RB
cord-309556-xv3413k1	22	6	detected	detect	VBN
cord-309556-xv3413k1	22	7	in	in	IN
cord-309556-xv3413k1	22	8	many	many	JJ
cord-309556-xv3413k1	22	9	different	different	JJ
cord-309556-xv3413k1	22	10	cell	cell	NN
cord-309556-xv3413k1	22	11	types	type	NNS
cord-309556-xv3413k1	22	12	including	include	VBG
cord-309556-xv3413k1	22	13	AT2	at2	NN
cord-309556-xv3413k1	22	14	cells	cell	NNS
cord-309556-xv3413k1	22	15	,	,	,
cord-309556-xv3413k1	22	16	but	but	CC
cord-309556-xv3413k1	22	17	its	-PRON-	PRP$
cord-309556-xv3413k1	22	18	expression	expression	NN
cord-309556-xv3413k1	22	19	was	be	VBD
cord-309556-xv3413k1	22	20	particularly	particularly	RB
cord-309556-xv3413k1	22	21	pronounced	pronounce	VBN
cord-309556-xv3413k1	22	22	in	in	IN
cord-309556-xv3413k1	22	23	macrophages	macrophage	NNS
cord-309556-xv3413k1	22	24	(	(	-LRB-
cord-309556-xv3413k1	22	25	Supplementary	Supplementary	NNP
cord-309556-xv3413k1	22	26	Figure	Figure	NNP
cord-309556-xv3413k1	22	27	3c	3c	CD
cord-309556-xv3413k1	22	28	)	)	-RRB-
cord-309556-xv3413k1	22	29	.	.	.
cord-309556-xv3413k1	23	1	Since	since	IN
cord-309556-xv3413k1	23	2	the	the	DT
cord-309556-xv3413k1	23	3	expression	expression	NN
cord-309556-xv3413k1	23	4	of	of	IN
cord-309556-xv3413k1	23	5	host	host	NN
cord-309556-xv3413k1	23	6	entry	entry	NN
cord-309556-xv3413k1	23	7	factors	factor	NNS
cord-309556-xv3413k1	23	8	ACE2	ACE2	NNP
cord-309556-xv3413k1	23	9	,	,	,
cord-309556-xv3413k1	23	10	TMPRSS2	TMPRSS2	NNP
cord-309556-xv3413k1	23	11	and	and	CC
cord-309556-xv3413k1	23	12	CTSL	CTSL	NNP
cord-309556-xv3413k1	23	13	did	do	VBD
cord-309556-xv3413k1	23	14	not	not	RB
cord-309556-xv3413k1	23	15	increase	increase	VB
cord-309556-xv3413k1	23	16	with	with	IN
cord-309556-xv3413k1	23	17	age	age	NN
cord-309556-xv3413k1	23	18	,	,	,
cord-309556-xv3413k1	23	19	we	-PRON-	PRP
cord-309556-xv3413k1	23	20	next	next	RB
cord-309556-xv3413k1	23	21	sought	seek	VBD
cord-309556-xv3413k1	23	22	to	to	TO
cord-309556-xv3413k1	23	23	identify	identify	VB
cord-309556-xv3413k1	23	24	all	all	DT
cord-309556-xv3413k1	23	25	age	age	NN
cord-309556-xv3413k1	23	26	-	-	HYPH
cord-309556-xv3413k1	23	27	associated	associate	VBN
cord-309556-xv3413k1	23	28	genes	gene	NNS
cord-309556-xv3413k1	23	29	expressed	express	VBN
cord-309556-xv3413k1	23	30	in	in	IN
cord-309556-xv3413k1	23	31	the	the	DT
cord-309556-xv3413k1	23	32	human	human	JJ
cord-309556-xv3413k1	23	33	lung	lung	NN
cord-309556-xv3413k1	23	34	(	(	-LRB-
cord-309556-xv3413k1	23	35	Methods	method	NNS
cord-309556-xv3413k1	23	36	)	)	-RRB-
cord-309556-xv3413k1	23	37	.	.	.
cord-309556-xv3413k1	24	1	Using	use	VBG
cord-309556-xv3413k1	24	2	a	a	DT
cord-309556-xv3413k1	24	3	likelihood	likelihood	NN
cord-309556-xv3413k1	24	4	-	-	HYPH
cord-309556-xv3413k1	24	5	ratio	ratio	NN
cord-309556-xv3413k1	24	6	test	test	NN
cord-309556-xv3413k1	24	7	22	22	CD
cord-309556-xv3413k1	24	8	,	,	,
cord-309556-xv3413k1	24	9	we	-PRON-	PRP
cord-309556-xv3413k1	24	10	pinpointed	pinpoint	VBD
cord-309556-xv3413k1	24	11	the	the	DT
cord-309556-xv3413k1	24	12	genes	gene	NNS
cord-309556-xv3413k1	24	13	for	for	IN
cord-309556-xv3413k1	24	14	which	which	WDT
cord-309556-xv3413k1	24	15	age	age	NN
cord-309556-xv3413k1	24	16	significantly	significantly	RB
cord-309556-xv3413k1	24	17	impacts	impact	VBZ
cord-309556-xv3413k1	24	18	their	-PRON-	PRP$
cord-309556-xv3413k1	24	19	expression	expression	NN
cord-309556-xv3413k1	24	20	.	.	.
cord-309556-xv3413k1	25	1	With	with	IN
cord-309556-xv3413k1	25	2	a	a	DT
cord-309556-xv3413k1	25	3	stringent	stringent	JJ
cord-309556-xv3413k1	25	4	cutoff	cutoff	NN
cord-309556-xv3413k1	25	5	of	of	IN
cord-309556-xv3413k1	25	6	adjusted	adjust	VBN
cord-309556-xv3413k1	25	7	p	p	NN
cord-309556-xv3413k1	25	8	<	<	XX
cord-309556-xv3413k1	25	9	0.0001	0.0001	CD
cord-309556-xv3413k1	25	10	,	,	,
cord-309556-xv3413k1	25	11	we	-PRON-	PRP
cord-309556-xv3413k1	25	12	identified	identify	VBD
cord-309556-xv3413k1	25	13	two	two	CD
cord-309556-xv3413k1	25	14	clusters	cluster	NNS
cord-309556-xv3413k1	25	15	of	of	IN
cord-309556-xv3413k1	25	16	genes	gene	NNS
cord-309556-xv3413k1	25	17	in	in	IN
cord-309556-xv3413k1	25	18	which	which	WDT
cord-309556-xv3413k1	25	19	their	-PRON-	PRP$
cord-309556-xv3413k1	25	20	expression	expression	NN
cord-309556-xv3413k1	25	21	progressively	progressively	RB
cord-309556-xv3413k1	25	22	changes	change	VBZ
cord-309556-xv3413k1	25	23	with	with	IN
cord-309556-xv3413k1	25	24	age	age	NN
cord-309556-xv3413k1	25	25	(	(	-LRB-
cord-309556-xv3413k1	25	26	Figure	figure	NN
cord-309556-xv3413k1	25	27	1d	1d	CD
cord-309556-xv3413k1	25	28	)	)	-RRB-
cord-309556-xv3413k1	25	29	.	.	.
cord-309556-xv3413k1	26	1	Cluster	cluster	NN
cord-309556-xv3413k1	26	2	1	1	CD
cord-309556-xv3413k1	26	3	is	be	VBZ
cord-309556-xv3413k1	26	4	composed	compose	VBN
cord-309556-xv3413k1	26	5	of	of	IN
cord-309556-xv3413k1	26	6	643	643	CD
cord-309556-xv3413k1	26	7	genes	gene	NNS
cord-309556-xv3413k1	26	8	that	that	WDT
cord-309556-xv3413k1	26	9	increase	increase	VBP
cord-309556-xv3413k1	26	10	in	in	IN
cord-309556-xv3413k1	26	11	expression	expression	NN
cord-309556-xv3413k1	26	12	with	with	IN
cord-309556-xv3413k1	26	13	age	age	NN
cord-309556-xv3413k1	26	14	,	,	,
cord-309556-xv3413k1	26	15	while	while	IN
cord-309556-xv3413k1	26	16	Cluster	cluster	NN
cord-309556-xv3413k1	26	17	2	2	CD
cord-309556-xv3413k1	26	18	contains	contain	VBZ
cord-309556-xv3413k1	26	19	642	642	CD
cord-309556-xv3413k1	26	20	genes	gene	NNS
cord-309556-xv3413k1	26	21	that	that	WDT
cord-309556-xv3413k1	26	22	decrease	decrease	VBP
cord-309556-xv3413k1	26	23	in	in	IN
cord-309556-xv3413k1	26	24	expression	expression	NN
cord-309556-xv3413k1	26	25	with	with	IN
cord-309556-xv3413k1	26	26	age	age	NN
cord-309556-xv3413k1	26	27	.	.	.
cord-309556-xv3413k1	27	1	Gene	gene	NN
cord-309556-xv3413k1	27	2	ontology	ontology	NN
cord-309556-xv3413k1	27	3	and	and	CC
cord-309556-xv3413k1	27	4	pathway	pathway	NN
cord-309556-xv3413k1	27	5	analysis	analysis	NN
cord-309556-xv3413k1	27	6	of	of	IN
cord-309556-xv3413k1	27	7	Cluster	cluster	NN
cord-309556-xv3413k1	27	8	1	1	CD
cord-309556-xv3413k1	27	9	genes	gene	NNS
cord-309556-xv3413k1	27	10	(	(	-LRB-
cord-309556-xv3413k1	27	11	increasing	increase	VBG
cord-309556-xv3413k1	27	12	with	with	IN
cord-309556-xv3413k1	27	13	age	age	NN
cord-309556-xv3413k1	27	14	)	)	-RRB-
cord-309556-xv3413k1	27	15	revealed	reveal	VBD
cord-309556-xv3413k1	27	16	significant	significant	JJ
cord-309556-xv3413k1	27	17	enrichment	enrichment	NN
cord-309556-xv3413k1	27	18	for	for	IN
cord-309556-xv3413k1	27	19	cell	cell	NN
cord-309556-xv3413k1	27	20	adhesion	adhesion	NN
cord-309556-xv3413k1	27	21	,	,	,
cord-309556-xv3413k1	27	22	vascular	vascular	JJ
cord-309556-xv3413k1	27	23	smooth	smooth	JJ
cord-309556-xv3413k1	27	24	muscle	muscle	NN
cord-309556-xv3413k1	27	25	contraction	contraction	NN
cord-309556-xv3413k1	27	26	,	,	,
cord-309556-xv3413k1	27	27	oxytocin	oxytocin	NN
cord-309556-xv3413k1	27	28	signaling	signal	VBG
cord-309556-xv3413k1	27	29	,	,	,
cord-309556-xv3413k1	27	30	and	and	CC
cord-309556-xv3413k1	27	31	platelet	platelet	NN
cord-309556-xv3413k1	27	32	activation	activation	NN
cord-309556-xv3413k1	27	33	,	,	,
cord-309556-xv3413k1	27	34	in	in	IN
cord-309556-xv3413k1	27	35	addition	addition	NN
cord-309556-xv3413k1	27	36	to	to	IN
cord-309556-xv3413k1	27	37	several	several	JJ
cord-309556-xv3413k1	27	38	other	other	JJ
cord-309556-xv3413k1	27	39	pathways	pathway	NNS
cord-309556-xv3413k1	27	40	(	(	-LRB-
cord-309556-xv3413k1	27	41	Figure	figure	NN
cord-309556-xv3413k1	27	42	1e	1e	CD
cord-309556-xv3413k1	27	43	)	)	-RRB-
cord-309556-xv3413k1	27	44	.	.	.
cord-309556-xv3413k1	28	1	These	these	DT
cord-309556-xv3413k1	28	2	findings	finding	NNS
cord-309556-xv3413k1	28	3	are	be	VBP
cord-309556-xv3413k1	28	4	consistent	consistent	JJ
cord-309556-xv3413k1	28	5	with	with	IN
cord-309556-xv3413k1	28	6	known	know	VBN
cord-309556-xv3413k1	28	7	physiologic	physiologic	JJ
cord-309556-xv3413k1	28	8	changes	change	NNS
cord-309556-xv3413k1	28	9	of	of	IN
cord-309556-xv3413k1	28	10	aging	age	VBG
cord-309556-xv3413k1	28	11	,	,	,
cord-309556-xv3413k1	28	12	including	include	VBG
cord-309556-xv3413k1	28	13	decreased	decrease	VBN
cord-309556-xv3413k1	28	14	pulmonary	pulmonary	JJ
cord-309556-xv3413k1	28	15	compliance	compliance	NN
cord-309556-xv3413k1	28	16	23	23	CD
cord-309556-xv3413k1	28	17	,	,	,
cord-309556-xv3413k1	28	18	and	and	CC
cord-309556-xv3413k1	28	19	heightened	heighten	VBD
cord-309556-xv3413k1	28	20	risk	risk	NN
cord-309556-xv3413k1	28	21	for	for	IN
cord-309556-xv3413k1	28	22	thrombotic	thrombotic	JJ
cord-309556-xv3413k1	28	23	diseases	disease	NNS
cord-309556-xv3413k1	28	24	24	24	CD
cord-309556-xv3413k1	28	25	.	.	.
cord-309556-xv3413k1	29	1	Of	of	IN
cord-309556-xv3413k1	29	2	note	note	NN
cord-309556-xv3413k1	29	3	,	,	,
cord-309556-xv3413k1	29	4	deregulation	deregulation	NN
cord-309556-xv3413k1	29	5	of	of	IN
cord-309556-xv3413k1	29	6	the	the	DT
cord-309556-xv3413k1	29	7	reninangiotensin	reninangiotensin	NNP
cord-309556-xv3413k1	29	8	system	system	NN
cord-309556-xv3413k1	29	9	has	have	VBZ
cord-309556-xv3413k1	29	10	been	be	VBN
cord-309556-xv3413k1	29	11	implicated	implicate	VBN
cord-309556-xv3413k1	29	12	in	in	IN
cord-309556-xv3413k1	29	13	the	the	DT
cord-309556-xv3413k1	29	14	pathogenesis	pathogenesis	NN
cord-309556-xv3413k1	29	15	of	of	IN
cord-309556-xv3413k1	29	16	acute	acute	JJ
cord-309556-xv3413k1	29	17	lung	lung	NN
cord-309556-xv3413k1	29	18	injury	injury	NN
cord-309556-xv3413k1	29	19	induced	induce	VBN
cord-309556-xv3413k1	29	20	by	by	IN
cord-309556-xv3413k1	29	21	SARS-	SARS-	NNP
cord-309556-xv3413k1	29	22	China	China	NNP
cord-309556-xv3413k1	29	23	and	and	CC
cord-309556-xv3413k1	29	24	Italy	Italy	NNP
cord-309556-xv3413k1	29	25	have	have	VBP
cord-309556-xv3413k1	29	26	found	find	VBN
cord-309556-xv3413k1	29	27	that	that	IN
cord-309556-xv3413k1	29	28	patients	patient	NNS
cord-309556-xv3413k1	29	29	with	with	IN
cord-309556-xv3413k1	29	30	hypertension	hypertension	NN
cord-309556-xv3413k1	29	31	were	be	VBD
cord-309556-xv3413k1	29	32	more	more	RBR
cord-309556-xv3413k1	29	33	likely	likely	JJ
cord-309556-xv3413k1	29	34	to	to	TO
cord-309556-xv3413k1	29	35	develop	develop	VB
cord-309556-xv3413k1	29	36	ARDS	ARDS	NNP
cord-309556-xv3413k1	29	37	17	17	CD
cord-309556-xv3413k1	29	38	,	,	,
cord-309556-xv3413k1	29	39	require	require	VB
cord-309556-xv3413k1	29	40	ICU	ICU	NNP
cord-309556-xv3413k1	29	41	admission	admission	NN
cord-309556-xv3413k1	29	42	31	31	CD
cord-309556-xv3413k1	29	43	,	,	,
cord-309556-xv3413k1	29	44	and	and	CC
cord-309556-xv3413k1	29	45	die	die	VB
cord-309556-xv3413k1	29	46	from	from	IN
cord-309556-xv3413k1	29	47	the	the	DT
cord-309556-xv3413k1	29	48	disease	disease	NN
cord-309556-xv3413k1	29	49	32	32	CD
cord-309556-xv3413k1	29	50	,	,	,
cord-309556-xv3413k1	29	51	though	though	IN
cord-309556-xv3413k1	29	52	we	-PRON-	PRP
cord-309556-xv3413k1	29	53	note	note	VBP
cord-309556-xv3413k1	29	54	that	that	IN
cord-309556-xv3413k1	29	55	correlative	correlative	JJ
cord-309556-xv3413k1	29	56	epidemiologic	epidemiologic	JJ
cord-309556-xv3413k1	29	57	studies	study	NNS
cord-309556-xv3413k1	29	58	do	do	VBP
cord-309556-xv3413k1	29	59	not	not	RB
cord-309556-xv3413k1	29	60	necessarily	necessarily	RB
cord-309556-xv3413k1	29	61	demonstrate	demonstrate	VB
cord-309556-xv3413k1	29	62	causality	causality	NN
cord-309556-xv3413k1	29	63	.	.	.
cord-309556-xv3413k1	30	1	Cluster	cluster	NN
cord-309556-xv3413k1	30	2	2	2	CD
cord-309556-xv3413k1	30	3	genes	gene	NNS
cord-309556-xv3413k1	30	4	(	(	-LRB-
cord-309556-xv3413k1	30	5	decreasing	decrease	VBG
cord-309556-xv3413k1	30	6	with	with	IN
cord-309556-xv3413k1	30	7	age	age	NN
cord-309556-xv3413k1	30	8	)	)	-RRB-
cord-309556-xv3413k1	30	9	were	be	VBD
cord-309556-xv3413k1	30	10	significantly	significantly	RB
cord-309556-xv3413k1	30	11	enriched	enrich	VBN
cord-309556-xv3413k1	30	12	for	for	IN
cord-309556-xv3413k1	30	13	mitochondrion	mitochondrion	NN
cord-309556-xv3413k1	30	14	,	,	,
cord-309556-xv3413k1	30	15	mitochondrial	mitochondrial	JJ
cord-309556-xv3413k1	30	16	translation	translation	NN
cord-309556-xv3413k1	30	17	,	,	,
cord-309556-xv3413k1	30	18	metabolic	metabolic	JJ
cord-309556-xv3413k1	30	19	pathways	pathway	NNS
cord-309556-xv3413k1	30	20	,	,	,
cord-309556-xv3413k1	30	21	and	and	CC
cord-309556-xv3413k1	30	22	mitosis	mitosis	NN
cord-309556-xv3413k1	30	23	,	,	,
cord-309556-xv3413k1	30	24	among	among	IN
cord-309556-xv3413k1	30	25	other	other	JJ
cord-309556-xv3413k1	30	26	pathways	pathway	NNS
cord-309556-xv3413k1	30	27	(	(	-LRB-
cord-309556-xv3413k1	30	28	Figure	figure	NN
cord-309556-xv3413k1	30	29	1f	1f	CD
cord-309556-xv3413k1	30	30	)	)	-RRB-
cord-309556-xv3413k1	30	31	,	,	,
cord-309556-xv3413k1	30	32	which	which	WDT
cord-309556-xv3413k1	30	33	is	be	VBZ
cord-309556-xv3413k1	30	34	consistent	consistent	JJ
cord-309556-xv3413k1	30	35	with	with	IN
cord-309556-xv3413k1	30	36	prior	prior	JJ
cord-309556-xv3413k1	30	37	observations	observation	NNS
cord-309556-xv3413k1	30	38	of	of	IN
cord-309556-xv3413k1	30	39	progressive	progressive	JJ
cord-309556-xv3413k1	30	40	mitochondrial	mitochondrial	JJ
cord-309556-xv3413k1	30	41	dysfunction	dysfunction	NN
cord-309556-xv3413k1	30	42	with	with	IN
cord-309556-xv3413k1	30	43	aging	age	VBG
cord-309556-xv3413k1	30	44	[	[	-LRB-
cord-309556-xv3413k1	30	45	33	33	CD
cord-309556-xv3413k1	30	46	]	]	-RRB-
cord-309556-xv3413k1	30	47	[	[	-LRB-
cord-309556-xv3413k1	30	48	34	34	CD
cord-309556-xv3413k1	30	49	]	]	-RRB-
cord-309556-xv3413k1	30	50	[	[	-LRB-
cord-309556-xv3413k1	30	51	35	35	CD
cord-309556-xv3413k1	30	52	]	]	-RRB-
cord-309556-xv3413k1	30	53	.	.	.
cord-309556-xv3413k1	31	1	Of	of	IN
cord-309556-xv3413k1	31	2	note	note	NN
cord-309556-xv3413k1	31	3	,	,	,
cord-309556-xv3413k1	31	4	Cluster	cluster	NN
cord-309556-xv3413k1	31	5	2	2	CD
cord-309556-xv3413k1	31	6	was	be	VBD
cord-309556-xv3413k1	31	7	also	also	RB
cord-309556-xv3413k1	31	8	enriched	enrich	VBN
cord-309556-xv3413k1	31	9	for	for	IN
cord-309556-xv3413k1	31	10	genes	gene	NNS
cord-309556-xv3413k1	31	11	involved	involve	VBN
cord-309556-xv3413k1	31	12	in	in	IN
cord-309556-xv3413k1	31	13	lipid	lipid	NN
cord-309556-xv3413k1	31	14	metabolism	metabolism	NN
cord-309556-xv3413k1	31	15	,	,	,
cord-309556-xv3413k1	31	16	fatty	fatty	JJ
cord-309556-xv3413k1	31	17	acid	acid	NN
cord-309556-xv3413k1	31	18	metabolism	metabolism	NN
cord-309556-xv3413k1	31	19	,	,	,
cord-309556-xv3413k1	31	20	peroxisome	peroxisome	NN
cord-309556-xv3413k1	31	21	,	,	,
cord-309556-xv3413k1	31	22	and	and	CC
cord-309556-xv3413k1	31	23	lysosomal	lysosomal	JJ
cord-309556-xv3413k1	31	24	membranes	membrane	NNS
cord-309556-xv3413k1	31	25	.	.	.
cord-309556-xv3413k1	32	1	Age	age	NN
cord-309556-xv3413k1	32	2	-	-	HYPH
cord-309556-xv3413k1	32	3	associated	associate	VBN
cord-309556-xv3413k1	32	4	alterations	alteration	NNS
cord-309556-xv3413k1	32	5	in	in	IN
cord-309556-xv3413k1	32	6	lipid	lipid	NN
cord-309556-xv3413k1	32	7	metabolism	metabolism	NN
cord-309556-xv3413k1	32	8	could	could	MD
cord-309556-xv3413k1	32	9	impact	impact	VB
cord-309556-xv3413k1	32	10	SARS	SARS	NNP
cord-309556-xv3413k1	32	11	-	-	HYPH
cord-309556-xv3413k1	32	12	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	32	13	infection	infection	NN
cord-309556-xv3413k1	32	14	,	,	,
cord-309556-xv3413k1	32	15	as	as	IN
cord-309556-xv3413k1	32	16	SARS	SARS	NNP
cord-309556-xv3413k1	32	17	-	-	HYPH
cord-309556-xv3413k1	32	18	CoV	CoV	NNP
cord-309556-xv3413k1	32	19	can	can	MD
cord-309556-xv3413k1	32	20	enter	enter	VB
cord-309556-xv3413k1	32	21	cells	cell	NNS
cord-309556-xv3413k1	32	22	through	through	IN
cord-309556-xv3413k1	32	23	cholesterol	cholesterol	NN
cord-309556-xv3413k1	32	24	-	-	HYPH
cord-309556-xv3413k1	32	25	rich	rich	JJ
cord-309556-xv3413k1	32	26	lipid	lipid	NN
cord-309556-xv3413k1	32	27	rafts	raft	NNS
cord-309556-xv3413k1	32	28	[	[	-LRB-
cord-309556-xv3413k1	32	29	36	36	CD
cord-309556-xv3413k1	32	30	]	]	-RRB-
cord-309556-xv3413k1	33	1	[	[	-LRB-
cord-309556-xv3413k1	33	2	37	37	CD
cord-309556-xv3413k1	33	3	]	]	-RRB-
cord-309556-xv3413k1	33	4	[	[	-LRB-
cord-309556-xv3413k1	33	5	38	38	CD
cord-309556-xv3413k1	33	6	]	]	-RRB-
cord-309556-xv3413k1	33	7	[	[	-LRB-
cord-309556-xv3413k1	33	8	39	39	CD
cord-309556-xv3413k1	33	9	]	]	-RRB-
cord-309556-xv3413k1	33	10	.	.	.
cord-309556-xv3413k1	34	1	Similarly	similarly	RB
cord-309556-xv3413k1	34	2	,	,	,
cord-309556-xv3413k1	34	3	age	age	NN
cord-309556-xv3413k1	34	4	-	-	HYPH
cord-309556-xv3413k1	34	5	associated	associate	VBN
cord-309556-xv3413k1	34	6	alterations	alteration	NNS
cord-309556-xv3413k1	34	7	in	in	IN
cord-309556-xv3413k1	34	8	lysosomes	lysosome	NNS
cord-309556-xv3413k1	34	9	could	could	MD
cord-309556-xv3413k1	34	10	influence	influence	VB
cord-309556-xv3413k1	34	11	late	late	RB
cord-309556-xv3413k1	34	12	endocytic	endocytic	JJ
cord-309556-xv3413k1	34	13	viral	viral	JJ
cord-309556-xv3413k1	34	14	entry	entry	NN
cord-309556-xv3413k1	34	15	,	,	,
cord-309556-xv3413k1	34	16	as	as	IN
cord-309556-xv3413k1	34	17	the	the	DT
cord-309556-xv3413k1	34	18	protease	protease	NN
cord-309556-xv3413k1	34	19	cathepsin	cathepsin	NN
cord-309556-xv3413k1	34	20	L	l	NN
cord-309556-xv3413k1	34	21	cleaves	cleave	VBZ
cord-309556-xv3413k1	34	22	SARS	SARS	NNP
cord-309556-xv3413k1	34	23	-	-	HYPH
cord-309556-xv3413k1	34	24	CoV	CoV	NNP
cord-309556-xv3413k1	34	25	spike	spike	NN
cord-309556-xv3413k1	34	26	proteins	protein	NNS
cord-309556-xv3413k1	34	27	from	from	IN
cord-309556-xv3413k1	34	28	within	within	IN
cord-309556-xv3413k1	34	29	lysosomes	lysosome	NNS
cord-309556-xv3413k1	34	30	40	40	CD
cord-309556-xv3413k1	34	31	,	,	,
cord-309556-xv3413k1	34	32	41	41	CD
cord-309556-xv3413k1	34	33	.	.	.
cord-309556-xv3413k1	35	1	Having	have	VBG
cord-309556-xv3413k1	35	2	compiled	compile	VBN
cord-309556-xv3413k1	35	3	a	a	DT
cord-309556-xv3413k1	35	4	high	high	JJ
cord-309556-xv3413k1	35	5	-	-	HYPH
cord-309556-xv3413k1	35	6	confidence	confidence	NN
cord-309556-xv3413k1	35	7	set	set	NN
cord-309556-xv3413k1	35	8	of	of	IN
cord-309556-xv3413k1	35	9	age	age	NN
cord-309556-xv3413k1	35	10	-	-	HYPH
cord-309556-xv3413k1	35	11	associated	associate	VBN
cord-309556-xv3413k1	35	12	genes	gene	NNS
cord-309556-xv3413k1	35	13	,	,	,
cord-309556-xv3413k1	35	14	we	-PRON-	PRP
cord-309556-xv3413k1	35	15	sought	seek	VBD
cord-309556-xv3413k1	35	16	to	to	TO
cord-309556-xv3413k1	35	17	identify	identify	VB
cord-309556-xv3413k1	35	18	the	the	DT
cord-309556-xv3413k1	35	19	lung	lung	NN
cord-309556-xv3413k1	35	20	cell	cell	NN
cord-309556-xv3413k1	35	21	types	type	NNS
cord-309556-xv3413k1	35	22	that	that	WDT
cord-309556-xv3413k1	35	23	normally	normally	RB
cord-309556-xv3413k1	35	24	express	express	VBP
cord-309556-xv3413k1	35	25	these	these	DT
cord-309556-xv3413k1	35	26	genes	gene	NNS
cord-309556-xv3413k1	35	27	,	,	,
cord-309556-xv3413k1	35	28	using	use	VBG
cord-309556-xv3413k1	35	29	the	the	DT
cord-309556-xv3413k1	35	30	human	human	JJ
cord-309556-xv3413k1	35	31	lung	lung	NN
cord-309556-xv3413k1	35	32	single	single	JJ
cord-309556-xv3413k1	35	33	cell	cell	NN
cord-309556-xv3413k1	35	34	transcriptomics	transcriptomic	NNS
cord-309556-xv3413k1	35	35	dataset	dataset	VBN
cord-309556-xv3413k1	35	36	from	from	IN
cord-309556-xv3413k1	35	37	the	the	DT
cord-309556-xv3413k1	35	38	Tissue	Tissue	NNP
cord-309556-xv3413k1	35	39	Stability	Stability	NNP
cord-309556-xv3413k1	35	40	Cell	Cell	NNP
cord-309556-xv3413k1	35	41	Atlas	Atlas	NNP
cord-309556-xv3413k1	35	42	19	19	CD
cord-309556-xv3413k1	35	43	.	.	.
cord-309556-xv3413k1	36	1	By	by	IN
cord-309556-xv3413k1	36	2	examining	examine	VBG
cord-309556-xv3413k1	36	3	the	the	DT
cord-309556-xv3413k1	36	4	scaled	scale	VBN
cord-309556-xv3413k1	36	5	percentage	percentage	NN
cord-309556-xv3413k1	36	6	of	of	IN
cord-309556-xv3413k1	36	7	expressing	express	VBG
cord-309556-xv3413k1	36	8	cells	cell	NNS
cord-309556-xv3413k1	36	9	within	within	IN
cord-309556-xv3413k1	36	10	each	each	DT
cord-309556-xv3413k1	36	11	cell	cell	NN
cord-309556-xv3413k1	36	12	subset	subset	VBN
cord-309556-xv3413k1	36	13	,	,	,
cord-309556-xv3413k1	36	14	we	-PRON-	PRP
cord-309556-xv3413k1	36	15	identified	identify	VBD
cord-309556-xv3413k1	36	16	age	age	NN
cord-309556-xv3413k1	36	17	-	-	HYPH
cord-309556-xv3413k1	36	18	associated	associate	VBN
cord-309556-xv3413k1	36	19	genes	gene	NNS
cord-309556-xv3413k1	36	20	predominantly	predominantly	RB
cord-309556-xv3413k1	36	21	enriched	enrich	VBN
cord-309556-xv3413k1	36	22	in	in	IN
cord-309556-xv3413k1	36	23	different	different	JJ
cord-309556-xv3413k1	36	24	cell	cell	NN
cord-309556-xv3413k1	36	25	types	type	NNS
cord-309556-xv3413k1	36	26	.	.	.
cord-309556-xv3413k1	37	1	Cell	cell	NN
cord-309556-xv3413k1	37	2	types	type	NNS
cord-309556-xv3413k1	37	3	with	with	IN
cord-309556-xv3413k1	37	4	highly	highly	RB
cord-309556-xv3413k1	37	5	enriched	enrich	VBN
cord-309556-xv3413k1	37	6	expression	expression	NN
cord-309556-xv3413k1	37	7	for	for	IN
cord-309556-xv3413k1	37	8	certain	certain	JJ
cord-309556-xv3413k1	37	9	Cluster	cluster	NN
cord-309556-xv3413k1	37	10	1	1	CD
cord-309556-xv3413k1	37	11	genes	gene	NNS
cord-309556-xv3413k1	37	12	(	(	-LRB-
cord-309556-xv3413k1	37	13	increasing	increase	VBG
cord-309556-xv3413k1	37	14	with	with	IN
cord-309556-xv3413k1	37	15	age	age	NN
cord-309556-xv3413k1	37	16	)	)	-RRB-
cord-309556-xv3413k1	37	17	included	include	VBD
cord-309556-xv3413k1	37	18	fibroblasts	fibroblast	NNS
cord-309556-xv3413k1	37	19	,	,	,
cord-309556-xv3413k1	37	20	muscle	muscle	NN
cord-309556-xv3413k1	37	21	cells	cell	NNS
cord-309556-xv3413k1	37	22	,	,	,
cord-309556-xv3413k1	37	23	and	and	CC
cord-309556-xv3413k1	37	24	lymph	lymph	NN
cord-309556-xv3413k1	37	25	vessels	vessel	NNS
cord-309556-xv3413k1	37	26	(	(	-LRB-
cord-309556-xv3413k1	37	27	Figure	figure	NN
cord-309556-xv3413k1	37	28	2a	2a	CD
cord-309556-xv3413k1	37	29	)	)	-RRB-
cord-309556-xv3413k1	37	30	.	.	.
cord-309556-xv3413k1	38	1	In	in	IN
cord-309556-xv3413k1	38	2	contrast	contrast	NN
cord-309556-xv3413k1	38	3	,	,	,
cord-309556-xv3413k1	38	4	cell	cell	NN
cord-309556-xv3413k1	38	5	types	type	NNS
cord-309556-xv3413k1	38	6	with	with	IN
cord-309556-xv3413k1	38	7	highly	highly	RB
cord-309556-xv3413k1	38	8	enriched	enrich	VBN
cord-309556-xv3413k1	38	9	expression	expression	NN
cord-309556-xv3413k1	38	10	for	for	IN
cord-309556-xv3413k1	38	11	certain	certain	JJ
cord-309556-xv3413k1	38	12	Cluster	cluster	NN
cord-309556-xv3413k1	38	13	2	2	CD
cord-309556-xv3413k1	38	14	genes	gene	NNS
cord-309556-xv3413k1	38	15	(	(	-LRB-
cord-309556-xv3413k1	38	16	decreasing	decrease	VBG
cord-309556-xv3413k1	38	17	with	with	IN
cord-309556-xv3413k1	38	18	age	age	NN
cord-309556-xv3413k1	38	19	)	)	-RRB-
cord-309556-xv3413k1	38	20	included	include	VBD
cord-309556-xv3413k1	38	21	macrophages	macrophage	NNS
cord-309556-xv3413k1	38	22	,	,	,
cord-309556-xv3413k1	38	23	dividing	divide	VBG
cord-309556-xv3413k1	38	24	dendritic	dendritic	JJ
cord-309556-xv3413k1	38	25	cells	cell	NNS
cord-309556-xv3413k1	38	26	(	(	-LRB-
cord-309556-xv3413k1	38	27	DCs)/monocytes	DCs)/monocytes	NNPS
cord-309556-xv3413k1	38	28	,	,	,
cord-309556-xv3413k1	38	29	and	and	CC
cord-309556-xv3413k1	38	30	AT2	at2	NN
cord-309556-xv3413k1	38	31	cells	cell	NNS
cord-309556-xv3413k1	38	32	(	(	-LRB-
cord-309556-xv3413k1	38	33	Figure	figure	NN
cord-309556-xv3413k1	38	34	2b	2b	CD
cord-309556-xv3413k1	38	35	)	)	-RRB-
cord-309556-xv3413k1	38	36	.	.	.
cord-309556-xv3413k1	39	1	Similar	similar	JJ
cord-309556-xv3413k1	39	2	results	result	NNS
cord-309556-xv3413k1	39	3	were	be	VBD
cord-309556-xv3413k1	39	4	found	find	VBN
cord-309556-xv3413k1	39	5	using	use	VBG
cord-309556-xv3413k1	39	6	an	an	DT
cord-309556-xv3413k1	39	7	independent	independent	JJ
cord-309556-xv3413k1	39	8	human	human	JJ
cord-309556-xv3413k1	39	9	lung	lung	NN
cord-309556-xv3413k1	39	10	scRNA	scRNA	NNP
cord-309556-xv3413k1	39	11	-	-	HYPH
cord-309556-xv3413k1	39	12	seq	seq	NN
cord-309556-xv3413k1	39	13	dataset	dataset	NN
cord-309556-xv3413k1	39	14	from	from	IN
cord-309556-xv3413k1	39	15	the	the	DT
cord-309556-xv3413k1	39	16	Human	Human	NNP
cord-309556-xv3413k1	39	17	Lung	Lung	NNP
cord-309556-xv3413k1	39	18	Cell	Cell	NNP
cord-309556-xv3413k1	39	19	Atlas	Atlas	NNP
cord-309556-xv3413k1	39	20	(	(	-LRB-
cord-309556-xv3413k1	39	21	Supplementary	Supplementary	NNP
cord-309556-xv3413k1	39	22	Figure	Figure	NNP
cord-309556-xv3413k1	39	23	4a	4a	NN
cord-309556-xv3413k1	39	24	-	-	HYPH
cord-309556-xv3413k1	39	25	b	b	NN
cord-309556-xv3413k1	39	26	)	)	-RRB-
cord-309556-xv3413k1	39	27	42	42	CD
cord-309556-xv3413k1	39	28	.	.	.
cord-309556-xv3413k1	40	1	Examining	examine	VBG
cord-309556-xv3413k1	40	2	the	the	DT
cord-309556-xv3413k1	40	3	muscle	muscle	NN
cord-309556-xv3413k1	40	4	-	-	HYPH
cord-309556-xv3413k1	40	5	enriched	enrich	VBN
cord-309556-xv3413k1	40	6	genes	gene	NNS
cord-309556-xv3413k1	40	7	that	that	WDT
cord-309556-xv3413k1	40	8	increased	increase	VBD
cord-309556-xv3413k1	40	9	in	in	IN
cord-309556-xv3413k1	40	10	expression	expression	NN
cord-309556-xv3413k1	40	11	with	with	IN
cord-309556-xv3413k1	40	12	age	age	NN
cord-309556-xv3413k1	40	13	,	,	,
cord-309556-xv3413k1	40	14	gene	gene	NN
cord-309556-xv3413k1	40	15	ontology	ontology	NN
cord-309556-xv3413k1	40	16	analysis	analysis	NN
cord-309556-xv3413k1	40	17	revealed	reveal	VBD
cord-309556-xv3413k1	40	18	enrichment	enrichment	NN
cord-309556-xv3413k1	40	19	for	for	IN
cord-309556-xv3413k1	40	20	vascular	vascular	JJ
cord-309556-xv3413k1	40	21	smooth	smooth	JJ
cord-309556-xv3413k1	40	22	muscle	muscle	NN
cord-309556-xv3413k1	40	23	contraction	contraction	NN
cord-309556-xv3413k1	40	24	,	,	,
cord-309556-xv3413k1	40	25	cGMP	cGMP	NNP
cord-309556-xv3413k1	40	26	-	-	HYPH
cord-309556-xv3413k1	40	27	PKG	pkg	NN
cord-309556-xv3413k1	40	28	signaling	signaling	NN
cord-309556-xv3413k1	40	29	,	,	,
cord-309556-xv3413k1	40	30	Z	z	NN
cord-309556-xv3413k1	40	31	-	-	HYPH
cord-309556-xv3413k1	40	32	disc	disc	NN
cord-309556-xv3413k1	40	33	,	,	,
cord-309556-xv3413k1	40	34	and	and	CC
cord-309556-xv3413k1	40	35	actin	actin	NN
cord-309556-xv3413k1	40	36	cytoskeleton	cytoskeleton	NN
cord-309556-xv3413k1	40	37	,	,	,
cord-309556-xv3413k1	40	38	among	among	IN
cord-309556-xv3413k1	40	39	other	other	JJ
cord-309556-xv3413k1	40	40	pathways	pathway	NNS
cord-309556-xv3413k1	40	41	(	(	-LRB-
cord-309556-xv3413k1	40	42	Figure	figure	NN
cord-309556-xv3413k1	40	43	  	  	_SP
cord-309556-xv3413k1	40	44	2c	2c	NN
cord-309556-xv3413k1	40	45	)	)	-RRB-
cord-309556-xv3413k1	40	46	.	.	.
cord-309556-xv3413k1	41	1	As	as	IN
cord-309556-xv3413k1	41	2	for	for	IN
cord-309556-xv3413k1	41	3	the	the	DT
cord-309556-xv3413k1	41	4	AT2-enriched	AT2-enriched	NNP
cord-309556-xv3413k1	41	5	genes	gene	NNS
cord-309556-xv3413k1	41	6	that	that	WDT
cord-309556-xv3413k1	41	7	decreased	decrease	VBD
cord-309556-xv3413k1	41	8	in	in	IN
cord-309556-xv3413k1	41	9	expression	expression	NN
cord-309556-xv3413k1	41	10	with	with	IN
cord-309556-xv3413k1	41	11	age	age	NN
cord-309556-xv3413k1	41	12	,	,	,
cord-309556-xv3413k1	41	13	gene	gene	NN
cord-309556-xv3413k1	41	14	ontology	ontology	NN
cord-309556-xv3413k1	41	15	analysis	analysis	NN
cord-309556-xv3413k1	41	16	revealed	reveal	VBD
cord-309556-xv3413k1	41	17	enrichment	enrichment	NN
cord-309556-xv3413k1	41	18	for	for	IN
cord-309556-xv3413k1	41	19	metabolic	metabolic	JJ
cord-309556-xv3413k1	41	20	pathways	pathway	NNS
cord-309556-xv3413k1	41	21	,	,	,
cord-309556-xv3413k1	41	22	biosynthesis	biosynthesis	NN
cord-309556-xv3413k1	41	23	of	of	IN
cord-309556-xv3413k1	41	24	antibiotics	antibiotic	NNS
cord-309556-xv3413k1	41	25	,	,	,
cord-309556-xv3413k1	41	26	lipid	lipid	NN
cord-309556-xv3413k1	41	27	metabolism	metabolism	NN
cord-309556-xv3413k1	41	28	,	,	,
cord-309556-xv3413k1	41	29	extracellular	extracellular	JJ
cord-309556-xv3413k1	41	30	exosome	exosome	NN
cord-309556-xv3413k1	41	31	,	,	,
cord-309556-xv3413k1	41	32	and	and	CC
cord-309556-xv3413k1	41	33	mitochondrial	mitochondrial	NN
cord-309556-xv3413k1	41	34	matrix	matrix	NN
cord-309556-xv3413k1	41	35	(	(	-LRB-
cord-309556-xv3413k1	41	36	Figure	Figure	NNP
cord-309556-xv3413k1	41	37	2d	2d	CD
cord-309556-xv3413k1	41	38	)	)	-RRB-
cord-309556-xv3413k1	41	39	.	.	.
cord-309556-xv3413k1	42	1	A	a	DT
cord-309556-xv3413k1	42	2	subset	subset	NN
cord-309556-xv3413k1	42	3	of	of	IN
cord-309556-xv3413k1	42	4	these	these	DT
cord-309556-xv3413k1	42	5	enriched	enrich	VBN
cord-309556-xv3413k1	42	6	gene	gene	NN
cord-309556-xv3413k1	42	7	ontologies	ontology	NNS
cord-309556-xv3413k1	42	8	had	have	VBD
cord-309556-xv3413k1	42	9	also	also	RB
cord-309556-xv3413k1	42	10	been	be	VBN
cord-309556-xv3413k1	42	11	identified	identify	VBN
cord-309556-xv3413k1	42	12	by	by	IN
cord-309556-xv3413k1	42	13	the	the	DT
cord-309556-xv3413k1	42	14	bulk	bulk	JJ
cord-309556-xv3413k1	42	15	RNA	RNA	NNP
cord-309556-xv3413k1	42	16	-	-	HYPH
cord-309556-xv3413k1	42	17	seq	seq	NN
cord-309556-xv3413k1	42	18	analysis	analysis	NN
cord-309556-xv3413k1	42	19	(	(	-LRB-
cord-309556-xv3413k1	42	20	Figure	figure	NN
cord-309556-xv3413k1	42	21	1e	1e	NNP
cord-309556-xv3413k1	42	22	-	-	HYPH
cord-309556-xv3413k1	42	23	f	f	NNP
cord-309556-xv3413k1	42	24	)	)	-RRB-
cord-309556-xv3413k1	42	25	.	.	.
cord-309556-xv3413k1	43	1	Thus	thus	RB
cord-309556-xv3413k1	43	2	,	,	,
cord-309556-xv3413k1	43	3	integrative	integrative	JJ
cord-309556-xv3413k1	43	4	analysis	analysis	NN
cord-309556-xv3413k1	43	5	of	of	IN
cord-309556-xv3413k1	43	6	bulk	bulk	JJ
cord-309556-xv3413k1	43	7	and	and	CC
cord-309556-xv3413k1	43	8	single	single	JJ
cord-309556-xv3413k1	43	9	-	-	HYPH
cord-309556-xv3413k1	43	10	cell	cell	NN
cord-309556-xv3413k1	43	11	transcriptomes	transcriptome	NNS
cord-309556-xv3413k1	43	12	revealed	reveal	VBD
cord-309556-xv3413k1	43	13	that	that	IN
cord-309556-xv3413k1	43	14	many	many	JJ
cord-309556-xv3413k1	43	15	of	of	IN
cord-309556-xv3413k1	43	16	the	the	DT
cord-309556-xv3413k1	43	17	age	age	NN
cord-309556-xv3413k1	43	18	-	-	HYPH
cord-309556-xv3413k1	43	19	associated	associate	VBN
cord-309556-xv3413k1	43	20	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	43	21	changes	change	NNS
cord-309556-xv3413k1	43	22	in	in	IN
cord-309556-xv3413k1	43	23	human	human	JJ
cord-309556-xv3413k1	43	24	lung	lung	NN
cord-309556-xv3413k1	43	25	can	can	MD
cord-309556-xv3413k1	43	26	be	be	VB
cord-309556-xv3413k1	43	27	mapped	map	VBN
cord-309556-xv3413k1	43	28	to	to	IN
cord-309556-xv3413k1	43	29	specific	specific	JJ
cord-309556-xv3413k1	43	30	cell	cell	NN
cord-309556-xv3413k1	43	31	subpopulations	subpopulation	NNS
cord-309556-xv3413k1	43	32	,	,	,
cord-309556-xv3413k1	43	33	suggesting	suggest	VBG
cord-309556-xv3413k1	43	34	that	that	IN
cord-309556-xv3413k1	43	35	the	the	DT
cord-309556-xv3413k1	43	36	overall	overall	JJ
cord-309556-xv3413k1	43	37	abundance	abundance	NN
cord-309556-xv3413k1	43	38	of	of	IN
cord-309556-xv3413k1	43	39	these	these	DT
cord-309556-xv3413k1	43	40	cell	cell	NN
cord-309556-xv3413k1	43	41	types	type	NNS
cord-309556-xv3413k1	43	42	,	,	,
cord-309556-xv3413k1	43	43	their	-PRON-	PRP$
cord-309556-xv3413k1	43	44	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	43	45	status	status	NN
cord-309556-xv3413k1	43	46	,	,	,
cord-309556-xv3413k1	43	47	or	or	CC
cord-309556-xv3413k1	43	48	both	both	DT
cord-309556-xv3413k1	43	49	,	,	,
cord-309556-xv3413k1	43	50	may	may	MD
cord-309556-xv3413k1	43	51	be	be	VB
cord-309556-xv3413k1	43	52	altered	alter	VBN
cord-309556-xv3413k1	43	53	with	with	IN
cord-309556-xv3413k1	43	54	aging	age	VBG
cord-309556-xv3413k1	43	55	.	.	.
cord-309556-xv3413k1	44	1	As	as	IN
cord-309556-xv3413k1	44	2	the	the	DT
cord-309556-xv3413k1	44	3	pathophysiology	pathophysiology	NN
cord-309556-xv3413k1	44	4	of	of	IN
cord-309556-xv3413k1	44	5	viral	viral	JJ
cord-309556-xv3413k1	44	6	-	-	HYPH
cord-309556-xv3413k1	44	7	induced	induce	VBN
cord-309556-xv3413k1	44	8	ARDS	ARDS	NNP
cord-309556-xv3413k1	44	9	involves	involve	VBZ
cord-309556-xv3413k1	44	10	an	an	DT
cord-309556-xv3413k1	44	11	intricate	intricate	JJ
cord-309556-xv3413k1	44	12	interplay	interplay	NN
cord-309556-xv3413k1	44	13	of	of	IN
cord-309556-xv3413k1	44	14	diverse	diverse	JJ
cord-309556-xv3413k1	44	15	cell	cell	NN
cord-309556-xv3413k1	44	16	types	type	NNS
cord-309556-xv3413k1	44	17	,	,	,
cord-309556-xv3413k1	44	18	most	most	RBS
cord-309556-xv3413k1	44	19	notably	notably	RB
cord-309556-xv3413k1	44	20	the	the	DT
cord-309556-xv3413k1	44	21	immune	immune	JJ
cord-309556-xv3413k1	44	22	system	system	NN
cord-309556-xv3413k1	44	23	43	43	CD
cord-309556-xv3413k1	44	24	,	,	,
cord-309556-xv3413k1	44	25	44	44	CD
cord-309556-xv3413k1	44	26	,	,	,
cord-309556-xv3413k1	44	27	aging	age	VBG
cord-309556-xv3413k1	44	28	-	-	HYPH
cord-309556-xv3413k1	44	29	associated	associate	VBN
cord-309556-xv3413k1	44	30	shifts	shift	NNS
cord-309556-xv3413k1	44	31	in	in	IN
cord-309556-xv3413k1	44	32	the	the	DT
cord-309556-xv3413k1	44	33	lung	lung	NN
cord-309556-xv3413k1	44	34	cellular	cellular	JJ
cord-309556-xv3413k1	44	35	milieu	milieu	NN
cord-309556-xv3413k1	44	36	23	23	CD
cord-309556-xv3413k1	44	37	could	could	MD
cord-309556-xv3413k1	44	38	contribute	contribute	VB
cord-309556-xv3413k1	44	39	an	an	DT
cord-309556-xv3413k1	44	40	important	important	JJ
cord-309556-xv3413k1	44	41	dimension	dimension	NN
cord-309556-xv3413k1	44	42	to	to	IN
cord-309556-xv3413k1	44	43	the	the	DT
cord-309556-xv3413k1	44	44	relationship	relationship	NN
cord-309556-xv3413k1	44	45	between	between	IN
cord-309556-xv3413k1	44	46	age	age	NN
cord-309556-xv3413k1	44	47	and	and	CC
cord-309556-xv3413k1	44	48	risk	risk	NN
cord-309556-xv3413k1	44	49	of	of	IN
cord-309556-xv3413k1	44	50	ARDS	ARDS	NNP
cord-309556-xv3413k1	44	51	in	in	IN
cord-309556-xv3413k1	44	52	patients	patient	NNS
cord-309556-xv3413k1	44	53	with	with	IN
cord-309556-xv3413k1	44	54	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	44	55	31	31	CD
cord-309556-xv3413k1	44	56	.	.	.
cord-309556-xv3413k1	45	1	To	to	TO
cord-309556-xv3413k1	45	2	investigate	investigate	VB
cord-309556-xv3413k1	45	3	the	the	DT
cord-309556-xv3413k1	45	4	cellular	cellular	JJ
cord-309556-xv3413k1	45	5	landscape	landscape	NN
cord-309556-xv3413k1	45	6	of	of	IN
cord-309556-xv3413k1	45	7	the	the	DT
cord-309556-xv3413k1	45	8	aging	age	VBG
cord-309556-xv3413k1	45	9	lung	lung	NN
cord-309556-xv3413k1	45	10	,	,	,
cord-309556-xv3413k1	45	11	we	-PRON-	PRP
cord-309556-xv3413k1	45	12	applied	apply	VBD
cord-309556-xv3413k1	45	13	a	a	DT
cord-309556-xv3413k1	45	14	gene	gene	NN
cord-309556-xv3413k1	45	15	signature	signature	NN
cord-309556-xv3413k1	45	16	-	-	HYPH
cord-309556-xv3413k1	45	17	based	base	VBN
cord-309556-xv3413k1	45	18	approach	approach	NN
cord-309556-xv3413k1	45	19	45	45	CD
cord-309556-xv3413k1	45	20	to	to	TO
cord-309556-xv3413k1	45	21	infer	infer	VB
cord-309556-xv3413k1	45	22	the	the	DT
cord-309556-xv3413k1	45	23	enrichment	enrichment	NN
cord-309556-xv3413k1	45	24	of	of	IN
cord-309556-xv3413k1	45	25	different	different	JJ
cord-309556-xv3413k1	45	26	cell	cell	NN
cord-309556-xv3413k1	45	27	types	type	NNS
cord-309556-xv3413k1	45	28	from	from	IN
cord-309556-xv3413k1	45	29	the	the	DT
cord-309556-xv3413k1	45	30	bulk	bulk	JJ
cord-309556-xv3413k1	45	31	RNA	RNA	NNP
cord-309556-xv3413k1	45	32	-	-	HYPH
cord-309556-xv3413k1	45	33	seq	seq	NN
cord-309556-xv3413k1	45	34	profiles	profile	NNS
cord-309556-xv3413k1	45	35	.	.	.
cord-309556-xv3413k1	46	1	Since	since	IN
cord-309556-xv3413k1	46	2	bulk	bulk	JJ
cord-309556-xv3413k1	46	3	RNA	RNA	NNP
cord-309556-xv3413k1	46	4	-	-	HYPH
cord-309556-xv3413k1	46	5	seq	seq	NN
cord-309556-xv3413k1	46	6	measures	measure	VBZ
cord-309556-xv3413k1	46	7	the	the	DT
cord-309556-xv3413k1	46	8	average	average	JJ
cord-309556-xv3413k1	46	9	expression	expression	NN
cord-309556-xv3413k1	46	10	of	of	IN
cord-309556-xv3413k1	46	11	genes	gene	NNS
cord-309556-xv3413k1	46	12	within	within	IN
cord-309556-xv3413k1	46	13	a	a	DT
cord-309556-xv3413k1	46	14	cell	cell	NN
cord-309556-xv3413k1	46	15	population	population	NN
cord-309556-xv3413k1	46	16	,	,	,
cord-309556-xv3413k1	46	17	such	such	JJ
cord-309556-xv3413k1	46	18	datasets	dataset	NNS
cord-309556-xv3413k1	46	19	will	will	MD
cord-309556-xv3413k1	46	20	reflect	reflect	VB
cord-309556-xv3413k1	46	21	the	the	DT
cord-309556-xv3413k1	46	22	relative	relative	JJ
cord-309556-xv3413k1	46	23	proportions	proportion	NNS
cord-309556-xv3413k1	46	24	of	of	IN
cord-309556-xv3413k1	46	25	the	the	DT
cord-309556-xv3413k1	46	26	cell	cell	NN
cord-309556-xv3413k1	46	27	types	type	NNS
cord-309556-xv3413k1	46	28	that	that	WDT
cord-309556-xv3413k1	46	29	comprised	comprise	VBD
cord-309556-xv3413k1	46	30	the	the	DT
cord-309556-xv3413k1	46	31	input	input	NN
cord-309556-xv3413k1	46	32	population	population	NN
cord-309556-xv3413k1	46	33	,	,	,
cord-309556-xv3413k1	46	34	though	though	IN
cord-309556-xv3413k1	46	35	with	with	IN
cord-309556-xv3413k1	46	36	the	the	DT
cord-309556-xv3413k1	46	37	caveat	caveat	NN
cord-309556-xv3413k1	46	38	that	that	IN
cord-309556-xv3413k1	46	39	cell	cell	NN
cord-309556-xv3413k1	46	40	types	type	NNS
cord-309556-xv3413k1	46	41	can	can	MD
cord-309556-xv3413k1	46	42	have	have	VB
cord-309556-xv3413k1	46	43	overlapping	overlapping	JJ
cord-309556-xv3413k1	46	44	expression	expression	NN
cord-309556-xv3413k1	46	45	profiles	profile	NNS
cord-309556-xv3413k1	46	46	and	and	CC
cord-309556-xv3413k1	46	47	such	such	JJ
cord-309556-xv3413k1	46	48	profiles	profile	NNS
cord-309556-xv3413k1	46	49	may	may	MD
cord-309556-xv3413k1	46	50	be	be	VB
cord-309556-xv3413k1	46	51	altered	alter	VBN
cord-309556-xv3413k1	46	52	in	in	IN
cord-309556-xv3413k1	46	53	response	response	NN
cord-309556-xv3413k1	46	54	to	to	IN
cord-309556-xv3413k1	46	55	stimuli	stimulus	NNS
cord-309556-xv3413k1	46	56	.	.	.
cord-309556-xv3413k1	47	1	Using	use	VBG
cord-309556-xv3413k1	47	2	this	this	DT
cord-309556-xv3413k1	47	3	approach	approach	NN
cord-309556-xv3413k1	47	4	,	,	,
cord-309556-xv3413k1	47	5	we	-PRON-	PRP
cord-309556-xv3413k1	47	6	identified	identify	VBD
cord-309556-xv3413k1	47	7	ageassociated	ageassociated	JJ
cord-309556-xv3413k1	47	8	alterations	alteration	NNS
cord-309556-xv3413k1	47	9	in	in	IN
cord-309556-xv3413k1	47	10	the	the	DT
cord-309556-xv3413k1	47	11	enrichment	enrichment	NN
cord-309556-xv3413k1	47	12	scores	score	NNS
cord-309556-xv3413k1	47	13	of	of	IN
cord-309556-xv3413k1	47	14	several	several	JJ
cord-309556-xv3413k1	47	15	cell	cell	NN
cord-309556-xv3413k1	47	16	types	type	NNS
cord-309556-xv3413k1	47	17	(	(	-LRB-
cord-309556-xv3413k1	47	18	Figure	figure	NN
cord-309556-xv3413k1	47	19	3a	3a	CD
cord-309556-xv3413k1	47	20	)	)	-RRB-
cord-309556-xv3413k1	47	21	.	.	.
cord-309556-xv3413k1	48	1	Whereas	whereas	IN
cord-309556-xv3413k1	48	2	epithelial	epithelial	JJ
cord-309556-xv3413k1	48	3	cells	cell	NNS
cord-309556-xv3413k1	48	4	decreased	decrease	VBD
cord-309556-xv3413k1	48	5	with	with	IN
cord-309556-xv3413k1	48	6	age	age	NN
cord-309556-xv3413k1	48	7	,	,	,
cord-309556-xv3413k1	48	8	fibroblasts	fibroblast	NNS
cord-309556-xv3413k1	48	9	increased	increase	VBD
cord-309556-xv3413k1	48	10	with	with	IN
cord-309556-xv3413k1	48	11	age	age	NN
cord-309556-xv3413k1	48	12	(	(	-LRB-
cord-309556-xv3413k1	48	13	Figure	figure	NN
cord-309556-xv3413k1	48	14	3b	3b	CD
cord-309556-xv3413k1	48	15	)	)	-RRB-
cord-309556-xv3413k1	48	16	.	.	.
cord-309556-xv3413k1	49	1	This	this	DT
cord-309556-xv3413k1	49	2	finding	finding	NN
cord-309556-xv3413k1	49	3	is	be	VBZ
cord-309556-xv3413k1	49	4	consistent	consistent	JJ
cord-309556-xv3413k1	49	5	with	with	IN
cord-309556-xv3413k1	49	6	the	the	DT
cord-309556-xv3413k1	49	7	progressive	progressive	JJ
cord-309556-xv3413k1	49	8	loss	loss	NN
cord-309556-xv3413k1	49	9	of	of	IN
cord-309556-xv3413k1	49	10	lung	lung	NN
cord-309556-xv3413k1	49	11	parenchyma	parenchyma	NN
cord-309556-xv3413k1	49	12	due	due	JJ
cord-309556-xv3413k1	49	13	to	to	IN
cord-309556-xv3413k1	49	14	reduced	reduce	VBN
cord-309556-xv3413k1	49	15	regenerative	regenerative	JJ
cord-309556-xv3413k1	49	16	capacity	capacity	NN
cord-309556-xv3413k1	49	17	of	of	IN
cord-309556-xv3413k1	49	18	the	the	DT
cord-309556-xv3413k1	49	19	aging	age	VBG
cord-309556-xv3413k1	49	20	lung	lung	NN
cord-309556-xv3413k1	49	21	46	46	CD
cord-309556-xv3413k1	49	22	,	,	,
cord-309556-xv3413k1	49	23	as	as	RB
cord-309556-xv3413k1	49	24	well	well	RB
cord-309556-xv3413k1	49	25	as	as	IN
cord-309556-xv3413k1	49	26	the	the	DT
cord-309556-xv3413k1	49	27	increased	increase	VBN
cord-309556-xv3413k1	49	28	risk	risk	NN
cord-309556-xv3413k1	49	29	for	for	IN
cord-309556-xv3413k1	49	30	diseases	disease	NNS
cord-309556-xv3413k1	49	31	such	such	JJ
cord-309556-xv3413k1	49	32	as	as	IN
cord-309556-xv3413k1	49	33	chronic	chronic	JJ
cord-309556-xv3413k1	49	34	obstructive	obstructive	JJ
cord-309556-xv3413k1	49	35	pulmonary	pulmonary	JJ
cord-309556-xv3413k1	49	36	disease	disease	NN
cord-309556-xv3413k1	49	37	and	and	CC
cord-309556-xv3413k1	49	38	pulmonary	pulmonary	JJ
cord-309556-xv3413k1	49	39	fibrosis	fibrosis	NN
cord-309556-xv3413k1	49	40	47	47	CD
cord-309556-xv3413k1	49	41	.	.	.
cord-309556-xv3413k1	50	1	In	in	IN
cord-309556-xv3413k1	50	2	addition	addition	NN
cord-309556-xv3413k1	50	3	,	,	,
cord-309556-xv3413k1	50	4	these	these	DT
cord-309556-xv3413k1	50	5	results	result	NNS
cord-309556-xv3413k1	50	6	are	be	VBP
cord-309556-xv3413k1	50	7	concordant	concordant	JJ
cord-309556-xv3413k1	50	8	with	with	IN
cord-309556-xv3413k1	50	9	the	the	DT
cord-309556-xv3413k1	50	10	findings	finding	NNS
cord-309556-xv3413k1	50	11	from	from	IN
cord-309556-xv3413k1	50	12	analysis	analysis	NN
cord-309556-xv3413k1	50	13	of	of	IN
cord-309556-xv3413k1	50	14	human	human	JJ
cord-309556-xv3413k1	50	15	lung	lung	NN
cord-309556-xv3413k1	50	16	single	single	JJ
cord-309556-xv3413k1	50	17	-	-	HYPH
cord-309556-xv3413k1	50	18	cell	cell	NN
cord-309556-xv3413k1	50	19	transcriptomes	transcriptome	NNS
cord-309556-xv3413k1	50	20	(	(	-LRB-
cord-309556-xv3413k1	50	21	Figure	Figure	NNP
cord-309556-xv3413k1	50	22	2a	2a	CD
cord-309556-xv3413k1	50	23	-	-	HYPH
cord-309556-xv3413k1	50	24	b	b	NN
cord-309556-xv3413k1	50	25	)	)	-RRB-
cord-309556-xv3413k1	50	26	.	.	.
cord-309556-xv3413k1	51	1	Among	among	IN
cord-309556-xv3413k1	51	2	the	the	DT
cord-309556-xv3413k1	51	3	innate	innate	JJ
cord-309556-xv3413k1	51	4	immune	immune	JJ
cord-309556-xv3413k1	51	5	cell	cell	NN
cord-309556-xv3413k1	51	6	populations	population	NNS
cord-309556-xv3413k1	51	7	,	,	,
cord-309556-xv3413k1	51	8	the	the	DT
cord-309556-xv3413k1	51	9	enrichment	enrichment	NN
cord-309556-xv3413k1	51	10	scores	score	NNS
cord-309556-xv3413k1	51	11	of	of	IN
cord-309556-xv3413k1	51	12	total	total	JJ
cord-309556-xv3413k1	51	13	macrophages	macrophage	NNS
cord-309556-xv3413k1	51	14	were	be	VBD
cord-309556-xv3413k1	51	15	inversely	inversely	RB
cord-309556-xv3413k1	51	16	associated	associate	VBN
cord-309556-xv3413k1	51	17	with	with	IN
cord-309556-xv3413k1	51	18	age	age	NN
cord-309556-xv3413k1	51	19	(	(	-LRB-
cord-309556-xv3413k1	51	20	Figure	figure	NN
cord-309556-xv3413k1	51	21	3c	3c	CD
cord-309556-xv3413k1	51	22	)	)	-RRB-
cord-309556-xv3413k1	51	23	.	.	.
cord-309556-xv3413k1	52	1	Macrophages	macrophage	NNS
cord-309556-xv3413k1	52	2	are	be	VBP
cord-309556-xv3413k1	52	3	major	major	JJ
cord-309556-xv3413k1	52	4	drivers	driver	NNS
cord-309556-xv3413k1	52	5	of	of	IN
cord-309556-xv3413k1	52	6	innate	innate	JJ
cord-309556-xv3413k1	52	7	immune	immune	JJ
cord-309556-xv3413k1	52	8	responses	response	NNS
cord-309556-xv3413k1	52	9	in	in	IN
cord-309556-xv3413k1	52	10	the	the	DT
cord-309556-xv3413k1	52	11	lung	lung	NN
cord-309556-xv3413k1	52	12	,	,	,
cord-309556-xv3413k1	52	13	acting	act	VBG
cord-309556-xv3413k1	52	14	as	as	IN
cord-309556-xv3413k1	52	15	first	first	JJ
cord-309556-xv3413k1	52	16	-	-	HYPH
cord-309556-xv3413k1	52	17	responders	responder	NNS
cord-309556-xv3413k1	52	18	against	against	IN
cord-309556-xv3413k1	52	19	diverse	diverse	JJ
cord-309556-xv3413k1	52	20	respiratory	respiratory	JJ
cord-309556-xv3413k1	52	21	infections	infection	NNS
cord-309556-xv3413k1	52	22	48	48	CD
cord-309556-xv3413k1	52	23	.	.	.
cord-309556-xv3413k1	53	1	Thus	thus	RB
cord-309556-xv3413k1	53	2	,	,	,
cord-309556-xv3413k1	53	3	the	the	DT
cord-309556-xv3413k1	53	4	age	age	NN
cord-309556-xv3413k1	53	5	-	-	HYPH
cord-309556-xv3413k1	53	6	associated	associate	VBN
cord-309556-xv3413k1	53	7	decrease	decrease	NN
cord-309556-xv3413k1	53	8	in	in	IN
cord-309556-xv3413k1	53	9	macrophage	macrophage	NN
cord-309556-xv3413k1	53	10	abundance	abundance	NN
cord-309556-xv3413k1	53	11	may	may	MD
cord-309556-xv3413k1	53	12	be	be	VB
cord-309556-xv3413k1	53	13	a	a	DT
cord-309556-xv3413k1	53	14	possible	possible	JJ
cord-309556-xv3413k1	53	15	factor	factor	NN
cord-309556-xv3413k1	53	16	related	relate	VBN
cord-309556-xv3413k1	53	17	to	to	IN
cord-309556-xv3413k1	53	18	the	the	DT
cord-309556-xv3413k1	53	19	greater	great	JJR
cord-309556-xv3413k1	53	20	severity	severity	NN
cord-309556-xv3413k1	53	21	of	of	IN
cord-309556-xv3413k1	53	22	lung	lung	NN
cord-309556-xv3413k1	53	23	pathology	pathology	NN
cord-309556-xv3413k1	53	24	in	in	IN
cord-309556-xv3413k1	53	25	patients	patient	NNS
cord-309556-xv3413k1	53	26	with	with	IN
cord-309556-xv3413k1	53	27	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	53	28	.	.	.
cord-309556-xv3413k1	54	1	Although	although	IN
cord-309556-xv3413k1	54	2	macrophage	macrophage	NN
cord-309556-xv3413k1	54	3	accumulation	accumulation	NN
cord-309556-xv3413k1	54	4	is	be	VBZ
cord-309556-xv3413k1	54	5	often	often	RB
cord-309556-xv3413k1	54	6	associated	associate	VBN
cord-309556-xv3413k1	54	7	with	with	IN
cord-309556-xv3413k1	54	8	the	the	DT
cord-309556-xv3413k1	54	9	pathologic	pathologic	JJ
cord-309556-xv3413k1	54	10	inflammation	inflammation	NN
cord-309556-xv3413k1	54	11	of	of	IN
cord-309556-xv3413k1	54	12	viral	viral	JJ
cord-309556-xv3413k1	54	13	ARDS	ARDS	NNP
cord-309556-xv3413k1	54	14	49	49	CD
cord-309556-xv3413k1	54	15	,	,	,
cord-309556-xv3413k1	54	16	50	50	CD
cord-309556-xv3413k1	54	17	,	,	,
cord-309556-xv3413k1	54	18	pulmonary	pulmonary	JJ
cord-309556-xv3413k1	54	19	macrophages	macrophage	NNS
cord-309556-xv3413k1	54	20	can	can	MD
cord-309556-xv3413k1	54	21	act	act	VB
cord-309556-xv3413k1	54	22	to	to	TO
cord-309556-xv3413k1	54	23	limit	limit	VB
cord-309556-xv3413k1	54	24	the	the	DT
cord-309556-xv3413k1	54	25	duration	duration	NN
cord-309556-xv3413k1	54	26	and	and	CC
cord-309556-xv3413k1	54	27	severity	severity	NN
cord-309556-xv3413k1	54	28	of	of	IN
cord-309556-xv3413k1	54	29	infection	infection	NN
cord-309556-xv3413k1	54	30	by	by	IN
cord-309556-xv3413k1	54	31	efficiently	efficiently	RB
cord-309556-xv3413k1	54	32	phagocytosing	phagocytose	VBG
cord-309556-xv3413k1	54	33	dead	dead	JJ
cord-309556-xv3413k1	54	34	infected	infected	JJ
cord-309556-xv3413k1	54	35	cells	cell	NNS
cord-309556-xv3413k1	54	36	and	and	CC
cord-309556-xv3413k1	54	37	released	release	VBN
cord-309556-xv3413k1	54	38	virions	virion	NNS
cord-309556-xv3413k1	54	39	[	[	-LRB-
cord-309556-xv3413k1	54	40	51	51	CD
cord-309556-xv3413k1	54	41	]	]	-RRB-
cord-309556-xv3413k1	55	1	[	[	-LRB-
cord-309556-xv3413k1	55	2	52	52	CD
cord-309556-xv3413k1	55	3	]	]	-RRB-
cord-309556-xv3413k1	56	1	[	[	-LRB-
cord-309556-xv3413k1	56	2	53	53	CD
cord-309556-xv3413k1	56	3	]	]	-RRB-
cord-309556-xv3413k1	56	4	.	.	.
cord-309556-xv3413k1	57	1	Notably	notably	RB
cord-309556-xv3413k1	57	2	,	,	,
cord-309556-xv3413k1	57	3	macrophages	macrophage	NNS
cord-309556-xv3413k1	57	4	infected	infect	VBN
cord-309556-xv3413k1	57	5	with	with	IN
cord-309556-xv3413k1	57	6	SARS	SARS	NNP
cord-309556-xv3413k1	57	7	-	-	HYPH
cord-309556-xv3413k1	57	8	CoV	CoV	NNP
cord-309556-xv3413k1	57	9	have	have	VBP
cord-309556-xv3413k1	57	10	been	be	VBN
cord-309556-xv3413k1	57	11	found	find	VBN
cord-309556-xv3413k1	57	12	to	to	TO
cord-309556-xv3413k1	57	13	abort	abort	VB
cord-309556-xv3413k1	57	14	the	the	DT
cord-309556-xv3413k1	57	15	replication	replication	NN
cord-309556-xv3413k1	57	16	cycle	cycle	NN
cord-309556-xv3413k1	57	17	of	of	IN
cord-309556-xv3413k1	57	18	the	the	DT
cord-309556-xv3413k1	57	19	virus	virus	NN
cord-309556-xv3413k1	57	20	54,55	54,55	CD
cord-309556-xv3413k1	57	21	,	,	,
cord-309556-xv3413k1	57	22	further	further	RB
cord-309556-xv3413k1	57	23	supporting	support	VBG
cord-309556-xv3413k1	57	24	their	-PRON-	PRP$
cord-309556-xv3413k1	57	25	role	role	NN
cord-309556-xv3413k1	57	26	in	in	IN
cord-309556-xv3413k1	57	27	antiviral	antiviral	JJ
cord-309556-xv3413k1	57	28	responses	response	NNS
cord-309556-xv3413k1	57	29	.	.	.
cord-309556-xv3413k1	58	1	However	however	RB
cord-309556-xv3413k1	58	2	,	,	,
cord-309556-xv3413k1	58	3	macrophages	macrophage	NNS
cord-309556-xv3413k1	58	4	may	may	MD
cord-309556-xv3413k1	58	5	suppress	suppress	VB
cord-309556-xv3413k1	58	6	antiviral	antiviral	JJ
cord-309556-xv3413k1	58	7	adaptive	adaptive	JJ
cord-309556-xv3413k1	58	8	immune	immune	JJ
cord-309556-xv3413k1	58	9	responses	response	NNS
cord-309556-xv3413k1	58	10	48	48	CD
cord-309556-xv3413k1	58	11	,	,	,
cord-309556-xv3413k1	58	12	56	56	CD
cord-309556-xv3413k1	58	13	,	,	,
cord-309556-xv3413k1	58	14	inhibiting	inhibit	VBG
cord-309556-xv3413k1	58	15	viral	viral	JJ
cord-309556-xv3413k1	58	16	clearance	clearance	NN
cord-309556-xv3413k1	58	17	in	in	IN
cord-309556-xv3413k1	58	18	mouse	mouse	NN
cord-309556-xv3413k1	58	19	models	model	NNS
cord-309556-xv3413k1	58	20	of	of	IN
cord-309556-xv3413k1	58	21	SARS	SARS	NNP
cord-309556-xv3413k1	58	22	-	-	HYPH
cord-309556-xv3413k1	58	23	CoV	CoV	NNP
cord-309556-xv3413k1	58	24	infection	infection	NN
cord-309556-xv3413k1	58	25	57	57	CD
cord-309556-xv3413k1	58	26	.	.	.
cord-309556-xv3413k1	59	1	In	in	IN
cord-309556-xv3413k1	59	2	aggregate	aggregate	NN
cord-309556-xv3413k1	59	3	,	,	,
cord-309556-xv3413k1	59	4	these	these	DT
cord-309556-xv3413k1	59	5	prior	prior	JJ
cord-309556-xv3413k1	59	6	reports	report	NNS
cord-309556-xv3413k1	59	7	suggest	suggest	VBP
cord-309556-xv3413k1	59	8	that	that	IN
cord-309556-xv3413k1	59	9	the	the	DT
cord-309556-xv3413k1	59	10	precise	precise	JJ
cord-309556-xv3413k1	59	11	role	role	NN
cord-309556-xv3413k1	59	12	of	of	IN
cord-309556-xv3413k1	59	13	lung	lung	NN
cord-309556-xv3413k1	59	14	macrophages	macrophage	NNS
cord-309556-xv3413k1	59	15	in	in	IN
cord-309556-xv3413k1	59	16	SARS	SARS	NNP
cord-309556-xv3413k1	59	17	-	-	HYPH
cord-309556-xv3413k1	59	18	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	59	19	pathophysiology	pathophysiology	NN
cord-309556-xv3413k1	59	20	is	be	VBZ
cord-309556-xv3413k1	59	21	likely	likely	RB
cord-309556-xv3413k1	59	22	contextdependent	contextdependent	JJ
cord-309556-xv3413k1	59	23	.	.	.
cord-309556-xv3413k1	60	1	It	-PRON-	PRP
cord-309556-xv3413k1	60	2	is	be	VBZ
cord-309556-xv3413k1	60	3	also	also	RB
cord-309556-xv3413k1	60	4	plausible	plausible	JJ
cord-309556-xv3413k1	60	5	that	that	IN
cord-309556-xv3413k1	60	6	the	the	DT
cord-309556-xv3413k1	60	7	increased	increase	VBN
cord-309556-xv3413k1	60	8	numbers	number	NNS
cord-309556-xv3413k1	60	9	of	of	IN
cord-309556-xv3413k1	60	10	macrophages	macrophage	NNS
cord-309556-xv3413k1	60	11	are	be	VBP
cord-309556-xv3413k1	60	12	not	not	RB
cord-309556-xv3413k1	60	13	the	the	DT
cord-309556-xv3413k1	60	14	primary	primary	JJ
cord-309556-xv3413k1	60	15	distinction	distinction	NN
cord-309556-xv3413k1	60	16	between	between	IN
cord-309556-xv3413k1	60	17	young	young	JJ
cord-309556-xv3413k1	60	18	and	and	CC
cord-309556-xv3413k1	60	19	old	old	JJ
cord-309556-xv3413k1	60	20	patients	patient	NNS
cord-309556-xv3413k1	60	21	,	,	,
cord-309556-xv3413k1	60	22	but	but	CC
cord-309556-xv3413k1	60	23	rather	rather	RB
cord-309556-xv3413k1	60	24	the	the	DT
cord-309556-xv3413k1	60	25	functional	functional	JJ
cord-309556-xv3413k1	60	26	status	status	NN
cord-309556-xv3413k1	60	27	of	of	IN
cord-309556-xv3413k1	60	28	the	the	DT
cord-309556-xv3413k1	60	29	macrophages	macrophage	NNS
cord-309556-xv3413k1	60	30	.	.	.
cord-309556-xv3413k1	61	1	In	in	IN
cord-309556-xv3413k1	61	2	line	line	NN
cord-309556-xv3413k1	61	3	with	with	IN
cord-309556-xv3413k1	61	4	this	this	DT
cord-309556-xv3413k1	61	5	,	,	,
cord-309556-xv3413k1	61	6	we	-PRON-	PRP
cord-309556-xv3413k1	61	7	observed	observe	VBD
cord-309556-xv3413k1	61	8	that	that	IN
cord-309556-xv3413k1	61	9	the	the	DT
cord-309556-xv3413k1	61	10	age	age	NN
cord-309556-xv3413k1	61	11	-	-	HYPH
cord-309556-xv3413k1	61	12	associated	associate	VBN
cord-309556-xv3413k1	61	13	changes	change	NNS
cord-309556-xv3413k1	61	14	in	in	IN
cord-309556-xv3413k1	61	15	macrophages	macrophage	NNS
cord-309556-xv3413k1	61	16	were	be	VBD
cord-309556-xv3413k1	61	17	specifically	specifically	RB
cord-309556-xv3413k1	61	18	attributed	attribute	VBN
cord-309556-xv3413k1	61	19	to	to	IN
cord-309556-xv3413k1	61	20	the	the	DT
cord-309556-xv3413k1	61	21	pro	pro	JJ
cord-309556-xv3413k1	61	22	-	-	JJ
cord-309556-xv3413k1	61	23	inflammatory	inflammatory	JJ
cord-309556-xv3413k1	61	24	M1	M1	NNP
cord-309556-xv3413k1	61	25	macrophage	macrophage	NN
cord-309556-xv3413k1	61	26	subset	subset	VBN
cord-309556-xv3413k1	61	27	but	but	CC
cord-309556-xv3413k1	61	28	not	not	RB
cord-309556-xv3413k1	61	29	the	the	DT
cord-309556-xv3413k1	61	30	immunoregulatory	immunoregulatory	JJ
cord-309556-xv3413k1	61	31	M2	M2	NNP
cord-309556-xv3413k1	61	32	subset	subset	VBN
cord-309556-xv3413k1	61	33	58	58	CD
cord-309556-xv3413k1	61	34	(	(	-LRB-
cord-309556-xv3413k1	61	35	Figure	figure	NN
cord-309556-xv3413k1	61	36	3c	3c	CD
cord-309556-xv3413k1	61	37	)	)	-RRB-
cord-309556-xv3413k1	61	38	,	,	,
cord-309556-xv3413k1	61	39	though	though	IN
cord-309556-xv3413k1	61	40	this	this	DT
cord-309556-xv3413k1	61	41	binary	binary	JJ
cord-309556-xv3413k1	61	42	classification	classification	NN
cord-309556-xv3413k1	61	43	scheme	scheme	NN
cord-309556-xv3413k1	61	44	represents	represent	VBZ
cord-309556-xv3413k1	61	45	an	an	DT
cord-309556-xv3413k1	61	46	oversimplification	oversimplification	NN
cord-309556-xv3413k1	61	47	of	of	IN
cord-309556-xv3413k1	61	48	macrophage	macrophage	NN
cord-309556-xv3413k1	61	49	function	function	NN
cord-309556-xv3413k1	61	50	.	.	.
cord-309556-xv3413k1	62	1	Nevertheless	nevertheless	RB
cord-309556-xv3413k1	62	2	,	,	,
cord-309556-xv3413k1	62	3	elucidating	elucidate	VBG
cord-309556-xv3413k1	62	4	the	the	DT
cord-309556-xv3413k1	62	5	consequences	consequence	NNS
cord-309556-xv3413k1	62	6	of	of	IN
cord-309556-xv3413k1	62	7	age	age	NN
cord-309556-xv3413k1	62	8	-	-	HYPH
cord-309556-xv3413k1	62	9	associated	associate	VBN
cord-309556-xv3413k1	62	10	changes	change	NNS
cord-309556-xv3413k1	62	11	in	in	IN
cord-309556-xv3413k1	62	12	lung	lung	NN
cord-309556-xv3413k1	62	13	macrophages	macrophage	NNS
cord-309556-xv3413k1	62	14	may	may	MD
cord-309556-xv3413k1	62	15	reveal	reveal	VB
cord-309556-xv3413k1	62	16	insights	insight	NNS
cord-309556-xv3413k1	62	17	into	into	IN
cord-309556-xv3413k1	62	18	the	the	DT
cord-309556-xv3413k1	62	19	differential	differential	JJ
cord-309556-xv3413k1	62	20	outcomes	outcome	NNS
cord-309556-xv3413k1	62	21	of	of	IN
cord-309556-xv3413k1	62	22	older	old	JJR
cord-309556-xv3413k1	62	23	patients	patient	NNS
cord-309556-xv3413k1	62	24	with	with	IN
cord-309556-xv3413k1	62	25	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	62	26	.	.	.
cord-309556-xv3413k1	63	1	Further	further	JJ
cord-309556-xv3413k1	63	2	studies	study	NNS
cord-309556-xv3413k1	63	3	are	be	VBP
cord-309556-xv3413k1	63	4	needed	need	VBN
cord-309556-xv3413k1	63	5	to	to	TO
cord-309556-xv3413k1	63	6	investigate	investigate	VB
cord-309556-xv3413k1	63	7	whether	whether	IN
cord-309556-xv3413k1	63	8	macrophages	macrophage	NNS
cord-309556-xv3413k1	63	9	or	or	CC
cord-309556-xv3413k1	63	10	other	other	JJ
cord-309556-xv3413k1	63	11	innate	innate	JJ
cord-309556-xv3413k1	63	12	immune	immune	JJ
cord-309556-xv3413k1	63	13	cells	cell	NNS
cord-309556-xv3413k1	63	14	respond	respond	VBP
cord-309556-xv3413k1	63	15	to	to	IN
cord-309556-xv3413k1	63	16	SARS	SARS	NNP
cord-309556-xv3413k1	63	17	-	-	HYPH
cord-309556-xv3413k1	63	18	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	63	19	infection	infection	NN
cord-309556-xv3413k1	63	20	,	,	,
cord-309556-xv3413k1	63	21	and	and	CC
cord-309556-xv3413k1	63	22	how	how	WRB
cord-309556-xv3413k1	63	23	their	-PRON-	PRP$
cord-309556-xv3413k1	63	24	numbers	number	NNS
cord-309556-xv3413k1	63	25	or	or	CC
cord-309556-xv3413k1	63	26	function	function	NN
cord-309556-xv3413k1	63	27	may	may	MD
cord-309556-xv3413k1	63	28	change	change	VB
cord-309556-xv3413k1	63	29	with	with	IN
cord-309556-xv3413k1	63	30	aging	age	VBG
cord-309556-xv3413k1	63	31	.	.	.
cord-309556-xv3413k1	64	1	Among	among	IN
cord-309556-xv3413k1	64	2	the	the	DT
cord-309556-xv3413k1	64	3	adaptive	adaptive	JJ
cord-309556-xv3413k1	64	4	immune	immune	JJ
cord-309556-xv3413k1	64	5	cell	cell	NN
cord-309556-xv3413k1	64	6	populations	population	NNS
cord-309556-xv3413k1	64	7	,	,	,
cord-309556-xv3413k1	64	8	we	-PRON-	PRP
cord-309556-xv3413k1	64	9	observed	observe	VBD
cord-309556-xv3413k1	64	10	that	that	IN
cord-309556-xv3413k1	64	11	Th1	th1	NN
cord-309556-xv3413k1	64	12	cells	cell	NNS
cord-309556-xv3413k1	64	13	and	and	CC
cord-309556-xv3413k1	64	14	CD4	CD4	NNP
cord-309556-xv3413k1	64	15	+	+	CC
cord-309556-xv3413k1	64	16	Tcm	Tcm	NNP
cord-309556-xv3413k1	64	17	cells	cell	NNS
cord-309556-xv3413k1	64	18	trended	trend	VBD
cord-309556-xv3413k1	64	19	in	in	IN
cord-309556-xv3413k1	64	20	opposite	opposite	JJ
cord-309556-xv3413k1	64	21	directions	direction	NNS
cord-309556-xv3413k1	64	22	with	with	IN
cord-309556-xv3413k1	64	23	aging	age	VBG
cord-309556-xv3413k1	64	24	(	(	-LRB-
cord-309556-xv3413k1	64	25	Figure	Figure	NNP
cord-309556-xv3413k1	64	26	3d	3d	NNP
cord-309556-xv3413k1	64	27	)	)	-RRB-
cord-309556-xv3413k1	64	28	.	.	.
cord-309556-xv3413k1	65	1	While	while	IN
cord-309556-xv3413k1	65	2	the	the	DT
cord-309556-xv3413k1	65	3	lungs	lung	NNS
cord-309556-xv3413k1	65	4	of	of	IN
cord-309556-xv3413k1	65	5	younger	young	JJR
cord-309556-xv3413k1	65	6	donors	donor	NNS
cord-309556-xv3413k1	65	7	were	be	VBD
cord-309556-xv3413k1	65	8	enriched	enrich	VBN
cord-309556-xv3413k1	65	9	for	for	IN
cord-309556-xv3413k1	65	10	Th1	th1	NN
cord-309556-xv3413k1	65	11	cells	cell	NNS
cord-309556-xv3413k1	65	12	,	,	,
cord-309556-xv3413k1	65	13	they	-PRON-	PRP
cord-309556-xv3413k1	65	14	were	be	VBD
cord-309556-xv3413k1	65	15	comparatively	comparatively	RB
cord-309556-xv3413k1	65	16	depleted	deplete	VBN
cord-309556-xv3413k1	65	17	for	for	IN
cord-309556-xv3413k1	65	18	CD4	CD4	NNP
cord-309556-xv3413k1	65	19	+	+	CC
cord-309556-xv3413k1	65	20	Tcm	Tcm	NNP
cord-309556-xv3413k1	65	21	cells	cell	NNS
cord-309556-xv3413k1	65	22	;	;	:
cord-309556-xv3413k1	65	23	the	the	DT
cord-309556-xv3413k1	65	24	inverse	inverse	NN
cord-309556-xv3413k1	65	25	was	be	VBD
cord-309556-xv3413k1	65	26	true	true	JJ
cord-309556-xv3413k1	65	27	in	in	IN
cord-309556-xv3413k1	65	28	the	the	DT
cord-309556-xv3413k1	65	29	lungs	lung	NNS
cord-309556-xv3413k1	65	30	of	of	IN
cord-309556-xv3413k1	65	31	older	old	JJR
cord-309556-xv3413k1	65	32	donors	donor	NNS
cord-309556-xv3413k1	65	33	.	.	.
cord-309556-xv3413k1	66	1	Of	of	IN
cord-309556-xv3413k1	66	2	note	note	NN
cord-309556-xv3413k1	66	3	,	,	,
cord-309556-xv3413k1	66	4	mouse	mouse	NN
cord-309556-xv3413k1	66	5	models	model	NNS
cord-309556-xv3413k1	66	6	of	of	IN
cord-309556-xv3413k1	66	7	SARS	SARS	NNP
cord-309556-xv3413k1	66	8	-	-	HYPH
cord-309556-xv3413k1	66	9	CoV	CoV	NNP
cord-309556-xv3413k1	66	10	infection	infection	NN
cord-309556-xv3413k1	66	11	have	have	VBP
cord-309556-xv3413k1	66	12	indicated	indicate	VBN
cord-309556-xv3413k1	66	13	important	important	JJ
cord-309556-xv3413k1	66	14	roles	role	NNS
cord-309556-xv3413k1	66	15	for	for	IN
cord-309556-xv3413k1	66	16	CD4	CD4	NNP
cord-309556-xv3413k1	66	17	+	+	CC
cord-309556-xv3413k1	66	18	T	T	NNP
cord-309556-xv3413k1	66	19	cell	cell	NN
cord-309556-xv3413k1	66	20	responses	response	NNS
cord-309556-xv3413k1	66	21	in	in	IN
cord-309556-xv3413k1	66	22	viral	viral	JJ
cord-309556-xv3413k1	66	23	clearance	clearance	NN
cord-309556-xv3413k1	66	24	59	59	CD
cord-309556-xv3413k1	66	25	,	,	,
cord-309556-xv3413k1	66	26	60	60	CD
cord-309556-xv3413k1	66	27	.	.	.
cord-309556-xv3413k1	67	1	Additionally	additionally	RB
cord-309556-xv3413k1	67	2	,	,	,
cord-309556-xv3413k1	67	3	Th1	th1	NN
cord-309556-xv3413k1	67	4	cells	cell	NNS
cord-309556-xv3413k1	67	5	are	be	VBP
cord-309556-xv3413k1	67	6	responsive	responsive	JJ
cord-309556-xv3413k1	67	7	to	to	IN
cord-309556-xv3413k1	67	8	SARS	SARS	NNP
cord-309556-xv3413k1	67	9	-	-	HYPH
cord-309556-xv3413k1	67	10	CoV	CoV	NNP
cord-309556-xv3413k1	67	11	vaccines	vaccine	NNS
cord-309556-xv3413k1	67	12	61	61	CD
cord-309556-xv3413k1	67	13	and	and	CC
cord-309556-xv3413k1	67	14	promote	promote	VB
cord-309556-xv3413k1	67	15	macrophage	macrophage	NN
cord-309556-xv3413k1	67	16	activation	activation	NN
cord-309556-xv3413k1	67	17	against	against	IN
cord-309556-xv3413k1	67	18	viruses	virus	NNS
cord-309556-xv3413k1	67	19	62	62	CD
cord-309556-xv3413k1	67	20	.	.	.
cord-309556-xv3413k1	68	1	It	-PRON-	PRP
cord-309556-xv3413k1	68	2	is	be	VBZ
cord-309556-xv3413k1	68	3	therefore	therefore	RB
cord-309556-xv3413k1	68	4	possible	possible	JJ
cord-309556-xv3413k1	68	5	that	that	IN
cord-309556-xv3413k1	68	6	age	age	NN
cord-309556-xv3413k1	68	7	-	-	HYPH
cord-309556-xv3413k1	68	8	associated	associate	VBN
cord-309556-xv3413k1	68	9	shifts	shift	NNS
cord-309556-xv3413k1	68	10	in	in	IN
cord-309556-xv3413k1	68	11	CD4	CD4	NNP
cord-309556-xv3413k1	68	12	+	+	CC
cord-309556-xv3413k1	68	13	T	t	NN
cord-309556-xv3413k1	68	14	cell	cell	NN
cord-309556-xv3413k1	68	15	subtypes	subtype	NNS
cord-309556-xv3413k1	68	16	within	within	IN
cord-309556-xv3413k1	68	17	the	the	DT
cord-309556-xv3413k1	68	18	lung	lung	NN
cord-309556-xv3413k1	68	19	may	may	MD
cord-309556-xv3413k1	68	20	influence	influence	VB
cord-309556-xv3413k1	68	21	the	the	DT
cord-309556-xv3413k1	68	22	subsequent	subsequent	JJ
cord-309556-xv3413k1	68	23	host	host	NN
cord-309556-xv3413k1	68	24	immune	immune	JJ
cord-309556-xv3413k1	68	25	response	response	NN
cord-309556-xv3413k1	68	26	in	in	IN
cord-309556-xv3413k1	68	27	response	response	NN
cord-309556-xv3413k1	68	28	to	to	IN
cord-309556-xv3413k1	68	29	coronavirus	coronavirus	NN
cord-309556-xv3413k1	68	30	infection	infection	NN
cord-309556-xv3413k1	68	31	.	.	.
cord-309556-xv3413k1	69	1	However	however	RB
cord-309556-xv3413k1	69	2	,	,	,
cord-309556-xv3413k1	69	3	future	future	JJ
cord-309556-xv3413k1	69	4	studies	study	NNS
cord-309556-xv3413k1	69	5	will	will	MD
cord-309556-xv3413k1	69	6	be	be	VB
cord-309556-xv3413k1	69	7	needed	need	VBN
cord-309556-xv3413k1	69	8	to	to	TO
cord-309556-xv3413k1	69	9	determine	determine	VB
cord-309556-xv3413k1	69	10	the	the	DT
cord-309556-xv3413k1	69	11	role	role	NN
cord-309556-xv3413k1	69	12	of	of	IN
cord-309556-xv3413k1	69	13	Th1	th1	NN
cord-309556-xv3413k1	69	14	cells	cell	NNS
cord-309556-xv3413k1	69	15	and	and	CC
cord-309556-xv3413k1	69	16	other	other	JJ
cord-309556-xv3413k1	69	17	adaptive	adaptive	JJ
cord-309556-xv3413k1	69	18	immune	immune	JJ
cord-309556-xv3413k1	69	19	cells	cell	NNS
cord-309556-xv3413k1	69	20	in	in	IN
cord-309556-xv3413k1	69	21	the	the	DT
cord-309556-xv3413k1	69	22	response	response	NN
cord-309556-xv3413k1	69	23	to	to	IN
cord-309556-xv3413k1	69	24	SARS	SARS	NNP
cord-309556-xv3413k1	69	25	-	-	HYPH
cord-309556-xv3413k1	69	26	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	69	27	,	,	,
cord-309556-xv3413k1	69	28	and	and	CC
cord-309556-xv3413k1	69	29	how	how	WRB
cord-309556-xv3413k1	69	30	these	these	DT
cord-309556-xv3413k1	69	31	dynamics	dynamic	NNS
cord-309556-xv3413k1	69	32	may	may	MD
cord-309556-xv3413k1	69	33	change	change	VB
cord-309556-xv3413k1	69	34	with	with	IN
cord-309556-xv3413k1	69	35	aging	age	VBG
cord-309556-xv3413k1	69	36	.	.	.
cord-309556-xv3413k1	70	1	We	-PRON-	PRP
cord-309556-xv3413k1	70	2	next	next	RB
cord-309556-xv3413k1	70	3	explored	explore	VBD
cord-309556-xv3413k1	70	4	the	the	DT
cord-309556-xv3413k1	70	5	roles	role	NNS
cord-309556-xv3413k1	70	6	of	of	IN
cord-309556-xv3413k1	70	7	lung	lung	NN
cord-309556-xv3413k1	70	8	age	age	NN
cord-309556-xv3413k1	70	9	-	-	HYPH
cord-309556-xv3413k1	70	10	associated	associate	VBN
cord-309556-xv3413k1	70	11	genes	gene	NNS
cord-309556-xv3413k1	70	12	in	in	IN
cord-309556-xv3413k1	70	13	host	host	NN
cord-309556-xv3413k1	70	14	responses	response	NNS
cord-309556-xv3413k1	70	15	to	to	IN
cord-309556-xv3413k1	70	16	viral	viral	JJ
cord-309556-xv3413k1	70	17	infection	infection	NN
cord-309556-xv3413k1	70	18	.	.	.
cord-309556-xv3413k1	71	1	Since	since	IN
cord-309556-xv3413k1	71	2	functional	functional	JJ
cord-309556-xv3413k1	71	3	screening	screening	NN
cord-309556-xv3413k1	71	4	data	datum	NNS
cord-309556-xv3413k1	71	5	with	with	IN
cord-309556-xv3413k1	71	6	SARS	SARS	NNP
cord-309556-xv3413k1	71	7	-	-	HYPH
cord-309556-xv3413k1	71	8	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	71	9	has	have	VBZ
cord-309556-xv3413k1	71	10	not	not	RB
cord-309556-xv3413k1	71	11	yet	yet	RB
cord-309556-xv3413k1	71	12	been	be	VBN
cord-309556-xv3413k1	71	13	described	describe	VBN
cord-309556-xv3413k1	71	14	(	(	-LRB-
cord-309556-xv3413k1	71	15	as	as	IN
cord-309556-xv3413k1	71	16	of	of	IN
cord-309556-xv3413k1	71	17	March	March	NNP
cord-309556-xv3413k1	71	18	30	30	CD
cord-309556-xv3413k1	71	19	,	,	,
cord-309556-xv3413k1	71	20	2020	2020	CD
cord-309556-xv3413k1	71	21	)	)	-RRB-
cord-309556-xv3413k1	71	22	,	,	,
cord-309556-xv3413k1	71	23	we	-PRON-	PRP
cord-309556-xv3413k1	71	24	instead	instead	RB
cord-309556-xv3413k1	71	25	searched	search	VBD
cord-309556-xv3413k1	71	26	for	for	IN
cord-309556-xv3413k1	71	27	data	datum	NNS
cord-309556-xv3413k1	71	28	on	on	IN
cord-309556-xv3413k1	71	29	SARS	SARS	NNP
cord-309556-xv3413k1	71	30	-	-	HYPH
cord-309556-xv3413k1	71	31	CoV.	CoV.	NNP
cord-309556-xv3413k1	71	32	While	while	IN
cord-309556-xv3413k1	71	33	these	these	DT
cord-309556-xv3413k1	71	34	two	two	CD
cord-309556-xv3413k1	71	35	viruses	virus	NNS
cord-309556-xv3413k1	71	36	belong	belong	VBP
cord-309556-xv3413k1	71	37	to	to	IN
cord-309556-xv3413k1	71	38	the	the	DT
cord-309556-xv3413k1	71	39	same	same	JJ
cord-309556-xv3413k1	71	40	genus	genus	NN
cord-309556-xv3413k1	71	41	(	(	-LRB-
cord-309556-xv3413k1	71	42	Betacoronaviridae	Betacoronaviridae	NNP
cord-309556-xv3413k1	71	43	)	)	-RRB-
cord-309556-xv3413k1	71	44	and	and	CC
cord-309556-xv3413k1	71	45	are	be	VBP
cord-309556-xv3413k1	71	46	conserved	conserve	VBN
cord-309556-xv3413k1	71	47	to	to	IN
cord-309556-xv3413k1	71	48	some	some	DT
cord-309556-xv3413k1	71	49	extent	extent	NN
cord-309556-xv3413k1	71	50	8	8	CD
cord-309556-xv3413k1	71	51	,	,	,
cord-309556-xv3413k1	71	52	they	-PRON-	PRP
cord-309556-xv3413k1	71	53	are	be	VBP
cord-309556-xv3413k1	71	54	nevertheless	nevertheless	RB
cord-309556-xv3413k1	71	55	two	two	CD
cord-309556-xv3413k1	71	56	distinct	distinct	JJ
cord-309556-xv3413k1	71	57	viruses	virus	NNS
cord-309556-xv3413k1	71	58	with	with	IN
cord-309556-xv3413k1	71	59	different	different	JJ
cord-309556-xv3413k1	71	60	epidemiological	epidemiological	JJ
cord-309556-xv3413k1	71	61	features	feature	NNS
cord-309556-xv3413k1	71	62	,	,	,
cord-309556-xv3413k1	71	63	indicating	indicate	VBG
cord-309556-xv3413k1	71	64	unique	unique	JJ
cord-309556-xv3413k1	71	65	virology	virology	NN
cord-309556-xv3413k1	71	66	and	and	CC
cord-309556-xv3413k1	71	67	host	host	NN
cord-309556-xv3413k1	71	68	biology	biology	NN
cord-309556-xv3413k1	71	69	.	.	.
cord-309556-xv3413k1	72	1	Therefore	therefore	RB
cord-309556-xv3413k1	72	2	,	,	,
cord-309556-xv3413k1	72	3	data	datum	NNS
cord-309556-xv3413k1	72	4	from	from	IN
cord-309556-xv3413k1	72	5	experiments	experiment	NNS
cord-309556-xv3413k1	72	6	performed	perform	VBN
cord-309556-xv3413k1	72	7	with	with	IN
cord-309556-xv3413k1	72	8	SARS	SARS	NNP
cord-309556-xv3413k1	72	9	-	-	HYPH
cord-309556-xv3413k1	72	10	CoV	CoV	NNP
cord-309556-xv3413k1	72	11	must	must	MD
cord-309556-xv3413k1	72	12	be	be	VB
cord-309556-xv3413k1	72	13	interpreted	interpret	VBN
cord-309556-xv3413k1	72	14	with	with	IN
cord-309556-xv3413k1	72	15	caution	caution	NN
cord-309556-xv3413k1	72	16	.	.	.
cord-309556-xv3413k1	73	1	We	-PRON-	PRP
cord-309556-xv3413k1	73	2	reassessed	reassess	VBD
cord-309556-xv3413k1	73	3	the	the	DT
cord-309556-xv3413k1	73	4	results	result	NNS
cord-309556-xv3413k1	73	5	from	from	IN
cord-309556-xv3413k1	73	6	a	a	DT
cord-309556-xv3413k1	74	1	prior	prior	RB
cord-309556-xv3413k1	74	2	in	in	IN
cord-309556-xv3413k1	74	3	vitro	vitro	FW
cord-309556-xv3413k1	74	4	siRNA	siRNA	NNP
cord-309556-xv3413k1	74	5	screen	screen	NN
cord-309556-xv3413k1	74	6	of	of	IN
cord-309556-xv3413k1	74	7	host	host	NN
cord-309556-xv3413k1	74	8	factors	factor	NNS
cord-309556-xv3413k1	74	9	involved	involve	VBN
cord-309556-xv3413k1	74	10	in	in	IN
cord-309556-xv3413k1	74	11	SARS	SARS	NNP
cord-309556-xv3413k1	74	12	-	-	HYPH
cord-309556-xv3413k1	74	13	CoV	CoV	NNP
cord-309556-xv3413k1	74	14	infection	infection	NN
cord-309556-xv3413k1	74	15	63	63	CD
cord-309556-xv3413k1	74	16	.	.	.
cord-309556-xv3413k1	75	1	In	in	IN
cord-309556-xv3413k1	75	2	this	this	DT
cord-309556-xv3413k1	75	3	kinase	kinase	NN
cord-309556-xv3413k1	75	4	-	-	HYPH
cord-309556-xv3413k1	75	5	focused	focus	VBN
cord-309556-xv3413k1	75	6	screen	screen	NN
cord-309556-xv3413k1	75	7	,	,	,
cord-309556-xv3413k1	75	8	130	130	CD
cord-309556-xv3413k1	75	9	factors	factor	NNS
cord-309556-xv3413k1	75	10	were	be	VBD
cord-309556-xv3413k1	75	11	determined	determine	VBN
cord-309556-xv3413k1	75	12	to	to	TO
cord-309556-xv3413k1	75	13	have	have	VB
cord-309556-xv3413k1	75	14	a	a	DT
cord-309556-xv3413k1	75	15	significant	significant	JJ
cord-309556-xv3413k1	75	16	effect	effect	NN
cord-309556-xv3413k1	75	17	on	on	IN
cord-309556-xv3413k1	75	18	SARS	SARS	NNP
cord-309556-xv3413k1	75	19	-	-	HYPH
cord-309556-xv3413k1	75	20	CoV	CoV	NNP
cord-309556-xv3413k1	75	21	replication	replication	NN
cord-309556-xv3413k1	75	22	.	.	.
cord-309556-xv3413k1	76	1	Notably	notably	RB
cord-309556-xv3413k1	76	2	,	,	,
cord-309556-xv3413k1	76	3	11	11	CD
cord-309556-xv3413k1	76	4	of	of	IN
cord-309556-xv3413k1	76	5	the	the	DT
cord-309556-xv3413k1	76	6	130	130	CD
cord-309556-xv3413k1	76	7	factors	factor	NNS
cord-309556-xv3413k1	76	8	exhibited	exhibit	VBD
cord-309556-xv3413k1	76	9	age	age	NN
cord-309556-xv3413k1	76	10	-	-	HYPH
cord-309556-xv3413k1	76	11	associated	associate	VBN
cord-309556-xv3413k1	76	12	gene	gene	NN
cord-309556-xv3413k1	76	13	expression	expression	NN
cord-309556-xv3413k1	76	14	patterns	pattern	NNS
cord-309556-xv3413k1	76	15	(	(	-LRB-
cord-309556-xv3413k1	76	16	Figure	figure	NN
cord-309556-xv3413k1	76	17	4a	4a	CD
cord-309556-xv3413k1	76	18	)	)	-RRB-
cord-309556-xv3413k1	76	19	,	,	,
cord-309556-xv3413k1	76	20	with	with	IN
cord-309556-xv3413k1	76	21	4	4	CD
cord-309556-xv3413k1	76	22	genes	gene	NNS
cord-309556-xv3413k1	76	23	in	in	IN
cord-309556-xv3413k1	76	24	Cluster	cluster	NN
cord-309556-xv3413k1	76	25	1	1	CD
cord-309556-xv3413k1	76	26	(	(	-LRB-
cord-309556-xv3413k1	76	27	increasing	increase	VBG
cord-309556-xv3413k1	76	28	with	with	IN
cord-309556-xv3413k1	76	29	age	age	NN
cord-309556-xv3413k1	76	30	)	)	-RRB-
cord-309556-xv3413k1	76	31	and	and	CC
cord-309556-xv3413k1	76	32	7	7	CD
cord-309556-xv3413k1	76	33	genes	gene	NNS
cord-309556-xv3413k1	76	34	in	in	IN
cord-309556-xv3413k1	76	35	Cluster	cluster	NN
cord-309556-xv3413k1	76	36	2	2	CD
cord-309556-xv3413k1	76	37	(	(	-LRB-
cord-309556-xv3413k1	76	38	decreasing	decrease	VBG
cord-309556-xv3413k1	76	39	with	with	IN
cord-309556-xv3413k1	76	40	age	age	NN
cord-309556-xv3413k1	76	41	)	)	-RRB-
cord-309556-xv3413k1	76	42	.	.	.
cord-309556-xv3413k1	77	1	The	the	DT
cord-309556-xv3413k1	77	2	4	4	CD
cord-309556-xv3413k1	77	3	genes	gene	NNS
cord-309556-xv3413k1	77	4	in	in	IN
cord-309556-xv3413k1	77	5	Cluster	cluster	NN
cord-309556-xv3413k1	77	6	1	1	CD
cord-309556-xv3413k1	77	7	were	be	VBD
cord-309556-xv3413k1	77	8	all	all	DT
cord-309556-xv3413k1	77	9	associated	associate	VBN
cord-309556-xv3413k1	77	10	with	with	IN
cord-309556-xv3413k1	77	11	increased	increase	VBN
cord-309556-xv3413k1	77	12	SARS	SARS	NNP
cord-309556-xv3413k1	77	13	infectivity	infectivity	NN
cord-309556-xv3413k1	77	14	upon	upon	IN
cord-309556-xv3413k1	77	15	siRNA	siRNA	NNP
cord-309556-xv3413k1	77	16	knockdown	knockdown	NNP
cord-309556-xv3413k1	77	17	;	;	:
cord-309556-xv3413k1	77	18	these	these	DT
cord-309556-xv3413k1	77	19	genes	gene	NNS
cord-309556-xv3413k1	77	20	included	include	VBD
cord-309556-xv3413k1	77	21	CLK1	CLK1	NNP
cord-309556-xv3413k1	77	22	,	,	,
cord-309556-xv3413k1	77	23	AKAP6	AKAP6	NNP
cord-309556-xv3413k1	77	24	,	,	,
cord-309556-xv3413k1	77	25	ALPK2	ALPK2	NNP
cord-309556-xv3413k1	77	26	,	,	,
cord-309556-xv3413k1	77	27	and	and	CC
cord-309556-xv3413k1	77	28	ITK	ITK	NNP
cord-309556-xv3413k1	77	29	.	.	.
cord-309556-xv3413k1	78	1	Paradoxically	paradoxically	RB
cord-309556-xv3413k1	78	2	,	,	,
cord-309556-xv3413k1	78	3	while	while	IN
cord-309556-xv3413k1	78	4	knockdown	knockdown	NN
cord-309556-xv3413k1	78	5	of	of	IN
cord-309556-xv3413k1	78	6	CLK1	CLK1	NNP
cord-309556-xv3413k1	78	7	was	be	VBD
cord-309556-xv3413k1	78	8	associated	associate	VBN
cord-309556-xv3413k1	78	9	with	with	IN
cord-309556-xv3413k1	78	10	increased	increase	VBN
cord-309556-xv3413k1	78	11	SARS	SARS	NNP
cord-309556-xv3413k1	78	12	infectivity	infectivity	NN
cord-309556-xv3413k1	78	13	,	,	,
cord-309556-xv3413k1	78	14	cell	cell	NN
cord-309556-xv3413k1	78	15	viability	viability	NN
cord-309556-xv3413k1	78	16	was	be	VBD
cord-309556-xv3413k1	78	17	also	also	RB
cord-309556-xv3413k1	78	18	found	find	VBN
cord-309556-xv3413k1	78	19	to	to	TO
cord-309556-xv3413k1	78	20	be	be	VB
cord-309556-xv3413k1	78	21	increased	increase	VBN
cord-309556-xv3413k1	78	22	(	(	-LRB-
cord-309556-xv3413k1	78	23	Figure	figure	NN
cord-309556-xv3413k1	78	24	4b	4b	CD
cord-309556-xv3413k1	78	25	)	)	-RRB-
cord-309556-xv3413k1	78	26	.	.	.
cord-309556-xv3413k1	79	1	Of	of	IN
cord-309556-xv3413k1	79	2	the	the	DT
cord-309556-xv3413k1	79	3	7	7	CD
cord-309556-xv3413k1	79	4	genes	gene	NNS
cord-309556-xv3413k1	79	5	in	in	IN
cord-309556-xv3413k1	79	6	Cluster	Cluster	NNP
cord-309556-xv3413k1	79	7	2	2	CD
cord-309556-xv3413k1	79	8	,	,	,
cord-309556-xv3413k1	79	9	6	6	CD
cord-309556-xv3413k1	79	10	were	be	VBD
cord-309556-xv3413k1	79	11	associated	associate	VBN
cord-309556-xv3413k1	79	12	with	with	IN
cord-309556-xv3413k1	79	13	increased	increase	VBN
cord-309556-xv3413k1	79	14	SARS	SARS	NNP
cord-309556-xv3413k1	79	15	infectivity	infectivity	NN
cord-309556-xv3413k1	79	16	and	and	CC
cord-309556-xv3413k1	79	17	reduced	reduced	JJ
cord-309556-xv3413k1	79	18	cell	cell	NN
cord-309556-xv3413k1	79	19	viability	viability	NN
cord-309556-xv3413k1	79	20	upon	upon	IN
cord-309556-xv3413k1	79	21	siRNA	siRNA	NNP
cord-309556-xv3413k1	79	22	knockdown	knockdown	NNP
cord-309556-xv3413k1	79	23	(	(	-LRB-
cord-309556-xv3413k1	79	24	AURKB	AURKB	NNP
cord-309556-xv3413k1	79	25	,	,	,
cord-309556-xv3413k1	79	26	CDKL2	CDKL2	NNP
cord-309556-xv3413k1	79	27	,	,	,
cord-309556-xv3413k1	79	28	PDIK1L	PDIK1L	NNP
cord-309556-xv3413k1	79	29	,	,	,
cord-309556-xv3413k1	79	30	CDKN3	CDKN3	NNP
cord-309556-xv3413k1	79	31	,	,	,
cord-309556-xv3413k1	79	32	MST1R	MST1R	NNP
cord-309556-xv3413k1	79	33	,	,	,
cord-309556-xv3413k1	79	34	and	and	CC
cord-309556-xv3413k1	79	35	ADK	ADK	NNP
cord-309556-xv3413k1	79	36	)	)	-RRB-
cord-309556-xv3413k1	79	37	.	.	.
cord-309556-xv3413k1	80	1	Age	age	NN
cord-309556-xv3413k1	80	2	-	-	HYPH
cord-309556-xv3413k1	80	3	related	relate	VBN
cord-309556-xv3413k1	80	4	downregulation	downregulation	NN
cord-309556-xv3413k1	80	5	of	of	IN
cord-309556-xv3413k1	80	6	these	these	DT
cord-309556-xv3413k1	80	7	6	6	CD
cord-309556-xv3413k1	80	8	factors	factor	NNS
cord-309556-xv3413k1	80	9	could	could	MD
cord-309556-xv3413k1	80	10	be	be	VB
cord-309556-xv3413k1	80	11	related	relate	VBN
cord-309556-xv3413k1	80	12	to	to	IN
cord-309556-xv3413k1	80	13	the	the	DT
cord-309556-xv3413k1	80	14	increased	increase	VBN
cord-309556-xv3413k1	80	15	severity	severity	NN
cord-309556-xv3413k1	80	16	of	of	IN
cord-309556-xv3413k1	80	17	illness	illness	NN
cord-309556-xv3413k1	80	18	in	in	IN
cord-309556-xv3413k1	80	19	older	old	JJR
cord-309556-xv3413k1	80	20	patients	patient	NNS
cord-309556-xv3413k1	80	21	.	.	.
cord-309556-xv3413k1	81	1	However	however	RB
cord-309556-xv3413k1	81	2	,	,	,
cord-309556-xv3413k1	81	3	we	-PRON-	PRP
cord-309556-xv3413k1	81	4	emphasize	emphasize	VBP
cord-309556-xv3413k1	81	5	that	that	IN
cord-309556-xv3413k1	81	6	until	until	IN
cord-309556-xv3413k1	81	7	rigorous	rigorous	JJ
cord-309556-xv3413k1	81	8	follow	follow	NN
cord-309556-xv3413k1	81	9	-	-	HYPH
cord-309556-xv3413k1	81	10	up	up	RP
cord-309556-xv3413k1	81	11	experiments	experiment	NNS
cord-309556-xv3413k1	81	12	are	be	VBP
cord-309556-xv3413k1	81	13	performed	perform	VBN
cord-309556-xv3413k1	81	14	with	with	IN
cord-309556-xv3413k1	81	15	SARS	SARS	NNP
cord-309556-xv3413k1	81	16	-	-	HYPH
cord-309556-xv3413k1	81	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	81	18	,	,	,
cord-309556-xv3413k1	81	19	the	the	DT
cord-309556-xv3413k1	81	20	therapeutic	therapeutic	JJ
cord-309556-xv3413k1	81	21	potential	potential	NN
cord-309556-xv3413k1	81	22	of	of	IN
cord-309556-xv3413k1	81	23	targeting	target	VBG
cord-309556-xv3413k1	81	24	these	these	DT
cord-309556-xv3413k1	81	25	factors	factor	NNS
cord-309556-xv3413k1	81	26	in	in	IN
cord-309556-xv3413k1	81	27	patients	patient	NNS
cord-309556-xv3413k1	81	28	with	with	IN
cord-309556-xv3413k1	81	29	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	81	30	is	be	VBZ
cord-309556-xv3413k1	81	31	unknown	unknown	JJ
cord-309556-xv3413k1	81	32	.	.	.
cord-309556-xv3413k1	82	1	Using	use	VBG
cord-309556-xv3413k1	82	2	the	the	DT
cord-309556-xv3413k1	82	3	human	human	JJ
cord-309556-xv3413k1	82	4	lung	lung	NN
cord-309556-xv3413k1	82	5	scRNA	scRNA	NNP
cord-309556-xv3413k1	82	6	-	-	HYPH
cord-309556-xv3413k1	82	7	seq	seq	NN
cord-309556-xv3413k1	82	8	data	datum	NNS
cord-309556-xv3413k1	82	9	,	,	,
cord-309556-xv3413k1	82	10	we	-PRON-	PRP
cord-309556-xv3413k1	82	11	then	then	RB
cord-309556-xv3413k1	82	12	determined	determine	VBD
cord-309556-xv3413k1	82	13	which	which	WDT
cord-309556-xv3413k1	82	14	cell	cell	NN
cord-309556-xv3413k1	82	15	types	type	NNS
cord-309556-xv3413k1	82	16	predominantly	predominantly	RB
cord-309556-xv3413k1	82	17	express	express	VBP
cord-309556-xv3413k1	82	18	these	these	DT
cord-309556-xv3413k1	82	19	host	host	NN
cord-309556-xv3413k1	82	20	factors	factor	NNS
cord-309556-xv3413k1	82	21	.	.	.
cord-309556-xv3413k1	83	1	Of	of	IN
cord-309556-xv3413k1	83	2	the	the	DT
cord-309556-xv3413k1	83	3	4	4	CD
cord-309556-xv3413k1	83	4	genes	gene	NNS
cord-309556-xv3413k1	83	5	in	in	IN
cord-309556-xv3413k1	83	6	Cluster	cluster	NN
cord-309556-xv3413k1	83	7	1	1	CD
cord-309556-xv3413k1	83	8	that	that	WDT
cord-309556-xv3413k1	83	9	had	have	VBD
cord-309556-xv3413k1	83	10	a	a	DT
cord-309556-xv3413k1	83	11	significant	significant	JJ
cord-309556-xv3413k1	83	12	impact	impact	NN
cord-309556-xv3413k1	83	13	on	on	IN
cord-309556-xv3413k1	83	14	SARS	SARS	NNP
cord-309556-xv3413k1	83	15	-	-	HYPH
cord-309556-xv3413k1	83	16	CoV	cov	NN
cord-309556-xv3413k1	83	17	replication	replication	NN
cord-309556-xv3413k1	83	18	,	,	,
cord-309556-xv3413k1	83	19	CLK1	CLK1	NNP
cord-309556-xv3413k1	83	20	was	be	VBD
cord-309556-xv3413k1	83	21	universally	universally	RB
cord-309556-xv3413k1	83	22	expressed	express	VBN
cord-309556-xv3413k1	83	23	,	,	,
cord-309556-xv3413k1	83	24	while	while	IN
cord-309556-xv3413k1	83	25	ALPK2	alpk2	JJ
cord-309556-xv3413k1	83	26	expression	expression	NN
cord-309556-xv3413k1	83	27	was	be	VBD
cord-309556-xv3413k1	83	28	rarely	rarely	RB
cord-309556-xv3413k1	83	29	detected	detect	VBN
cord-309556-xv3413k1	83	30	(	(	-LRB-
cord-309556-xv3413k1	83	31	Figure	figure	NN
cord-309556-xv3413k1	83	32	4c	4c	CD
cord-309556-xv3413k1	83	33	,	,	,
cord-309556-xv3413k1	83	34	Supplementary	Supplementary	NNP
cord-309556-xv3413k1	83	35	Figure	Figure	NNP
cord-309556-xv3413k1	83	36	5a	5a	CD
cord-309556-xv3413k1	83	37	)	)	-RRB-
cord-309556-xv3413k1	83	38	.	.	.
cord-309556-xv3413k1	84	1	ITK	ITK	NNP
cord-309556-xv3413k1	84	2	was	be	VBD
cord-309556-xv3413k1	84	3	preferentially	preferentially	RB
cord-309556-xv3413k1	84	4	expressed	express	VBN
cord-309556-xv3413k1	84	5	in	in	IN
cord-309556-xv3413k1	84	6	lymphocytic	lymphocytic	JJ
cord-309556-xv3413k1	84	7	populations	population	NNS
cord-309556-xv3413k1	84	8	,	,	,
cord-309556-xv3413k1	84	9	and	and	CC
cord-309556-xv3413k1	84	10	AKAP6	AKAP6	NNP
cord-309556-xv3413k1	84	11	was	be	VBD
cord-309556-xv3413k1	84	12	most	most	RBS
cord-309556-xv3413k1	84	13	frequently	frequently	RB
cord-309556-xv3413k1	84	14	expressed	express	VBN
cord-309556-xv3413k1	84	15	in	in	IN
cord-309556-xv3413k1	84	16	ciliated	ciliated	JJ
cord-309556-xv3413k1	84	17	cells	cell	NNS
cord-309556-xv3413k1	84	18	and	and	CC
cord-309556-xv3413k1	84	19	muscle	muscle	NN
cord-309556-xv3413k1	84	20	cells	cell	NNS
cord-309556-xv3413k1	84	21	.	.	.
cord-309556-xv3413k1	85	1	Of	of	IN
cord-309556-xv3413k1	85	2	the	the	DT
cord-309556-xv3413k1	85	3	7	7	CD
cord-309556-xv3413k1	85	4	overlapping	overlapping	JJ
cord-309556-xv3413k1	85	5	genes	gene	NNS
cord-309556-xv3413k1	85	6	in	in	IN
cord-309556-xv3413k1	85	7	Cluster	Cluster	NNP
cord-309556-xv3413k1	85	8	2	2	CD
cord-309556-xv3413k1	85	9	,	,	,
cord-309556-xv3413k1	85	10	AURKB	AURKB	NNP
cord-309556-xv3413k1	85	11	and	and	CC
cord-309556-xv3413k1	85	12	CDKN3	CDKN3	NNP
cord-309556-xv3413k1	85	13	were	be	VBD
cord-309556-xv3413k1	85	14	predominantly	predominantly	RB
cord-309556-xv3413k1	85	15	expressed	express	VBN
cord-309556-xv3413k1	85	16	in	in	IN
cord-309556-xv3413k1	85	17	proliferating	proliferate	VBG
cord-309556-xv3413k1	85	18	immune	immune	JJ
cord-309556-xv3413k1	85	19	cell	cell	NN
cord-309556-xv3413k1	85	20	populations	population	NNS
cord-309556-xv3413k1	85	21	,	,	,
cord-309556-xv3413k1	85	22	such	such	JJ
cord-309556-xv3413k1	85	23	as	as	IN
cord-309556-xv3413k1	85	24	macrophages	macrophage	NNS
cord-309556-xv3413k1	85	25	,	,	,
cord-309556-xv3413k1	85	26	DCs	DCs	NNP
cord-309556-xv3413k1	85	27	/	/	SYM
cord-309556-xv3413k1	85	28	monocytes	monocyte	NNS
cord-309556-xv3413k1	85	29	,	,	,
cord-309556-xv3413k1	85	30	T	t	NN
cord-309556-xv3413k1	85	31	cells	cell	NNS
cord-309556-xv3413k1	85	32	,	,	,
cord-309556-xv3413k1	85	33	and	and	CC
cord-309556-xv3413k1	85	34	NK	NK	NNP
cord-309556-xv3413k1	85	35	cells	cell	NNS
cord-309556-xv3413k1	85	36	(	(	-LRB-
cord-309556-xv3413k1	85	37	Figure	figure	NN
cord-309556-xv3413k1	85	38	4d	4d	CD
cord-309556-xv3413k1	85	39	,	,	,
cord-309556-xv3413k1	85	40	Supplementary	Supplementary	NNP
cord-309556-xv3413k1	85	41	Figure	Figure	NNP
cord-309556-xv3413k1	85	42	5b	5b	CD
cord-309556-xv3413k1	85	43	)	)	-RRB-
cord-309556-xv3413k1	85	44	.	.	.
cord-309556-xv3413k1	86	1	MST1R	MST1R	NNP
cord-309556-xv3413k1	86	2	,	,	,
cord-309556-xv3413k1	86	3	PDIK1L	PDIK1L	NNP
cord-309556-xv3413k1	86	4	,	,	,
cord-309556-xv3413k1	86	5	and	and	CC
cord-309556-xv3413k1	86	6	PSKH1	PSKH1	NNP
cord-309556-xv3413k1	86	7	were	be	VBD
cord-309556-xv3413k1	86	8	infrequently	infrequently	RB
cord-309556-xv3413k1	86	9	expressed	express	VBN
cord-309556-xv3413k1	86	10	,	,	,
cord-309556-xv3413k1	86	11	through	through	IN
cord-309556-xv3413k1	86	12	their	-PRON-	PRP$
cord-309556-xv3413k1	86	13	expression	expression	NN
cord-309556-xv3413k1	86	14	was	be	VBD
cord-309556-xv3413k1	86	15	detected	detect	VBN
cord-309556-xv3413k1	86	16	in	in	IN
cord-309556-xv3413k1	86	17	a	a	DT
cord-309556-xv3413k1	86	18	portion	portion	NN
cord-309556-xv3413k1	86	19	of	of	IN
cord-309556-xv3413k1	86	20	AT2	at2	NN
cord-309556-xv3413k1	86	21	cells	cell	NNS
cord-309556-xv3413k1	86	22	(	(	-LRB-
cord-309556-xv3413k1	86	23	5.54	5.54	CD
cord-309556-xv3413k1	86	24	%	%	NN
cord-309556-xv3413k1	86	25	,	,	,
cord-309556-xv3413k1	86	26	5.30	5.30	CD
cord-309556-xv3413k1	86	27	%	%	NN
cord-309556-xv3413k1	86	28	,	,	,
cord-309556-xv3413k1	86	29	and	and	CC
cord-309556-xv3413k1	86	30	5.47	5.47	CD
cord-309556-xv3413k1	86	31	%	%	NN
cord-309556-xv3413k1	86	32	,	,	,
cord-309556-xv3413k1	86	33	respectively	respectively	RB
cord-309556-xv3413k1	86	34	)	)	-RRB-
cord-309556-xv3413k1	86	35	.	.	.
cord-309556-xv3413k1	87	1	Finally	finally	RB
cord-309556-xv3413k1	87	2	,	,	,
cord-309556-xv3413k1	87	3	ADK	ADK	NNP
cord-309556-xv3413k1	87	4	and	and	CC
cord-309556-xv3413k1	87	5	CDKL2	CDKL2	NNP
cord-309556-xv3413k1	87	6	exhibited	exhibit	VBD
cord-309556-xv3413k1	87	7	preferential	preferential	JJ
cord-309556-xv3413k1	87	8	enrichment	enrichment	NN
cord-309556-xv3413k1	87	9	in	in	IN
cord-309556-xv3413k1	87	10	AT2	at2	NN
cord-309556-xv3413k1	87	11	cells	cell	NNS
cord-309556-xv3413k1	87	12	(	(	-LRB-
cord-309556-xv3413k1	87	13	51.40	51.40	CD
cord-309556-xv3413k1	87	14	%	%	NN
cord-309556-xv3413k1	87	15	and	and	CC
cord-309556-xv3413k1	87	16	34.43	34.43	CD
cord-309556-xv3413k1	87	17	%	%	NN
cord-309556-xv3413k1	87	18	)	)	-RRB-
cord-309556-xv3413k1	87	19	.	.	.
cord-309556-xv3413k1	88	1	In	in	IN
cord-309556-xv3413k1	88	2	aggregate	aggregate	NN
cord-309556-xv3413k1	88	3	,	,	,
cord-309556-xv3413k1	88	4	these	these	DT
cord-309556-xv3413k1	88	5	analyses	analysis	NNS
cord-309556-xv3413k1	88	6	showed	show	VBD
cord-309556-xv3413k1	88	7	that	that	IN
cord-309556-xv3413k1	88	8	the	the	DT
cord-309556-xv3413k1	88	9	age	age	NN
cord-309556-xv3413k1	88	10	-	-	HYPH
cord-309556-xv3413k1	88	11	associated	associate	VBN
cord-309556-xv3413k1	88	12	genes	gene	NNS
cord-309556-xv3413k1	88	13	with	with	IN
cord-309556-xv3413k1	88	14	functional	functional	JJ
cord-309556-xv3413k1	88	15	roles	role	NNS
cord-309556-xv3413k1	88	16	in	in	IN
cord-309556-xv3413k1	88	17	SARS	SARS	NNP
cord-309556-xv3413k1	88	18	-	-	HYPH
cord-309556-xv3413k1	88	19	CoV	CoV	NNP
cord-309556-xv3413k1	88	20	are	be	VBP
cord-309556-xv3413k1	88	21	expressed	express	VBN
cord-309556-xv3413k1	88	22	in	in	IN
cord-309556-xv3413k1	88	23	specific	specific	JJ
cord-309556-xv3413k1	88	24	cell	cell	NN
cord-309556-xv3413k1	88	25	types	type	NNS
cord-309556-xv3413k1	88	26	of	of	IN
cord-309556-xv3413k1	88	27	the	the	DT
cord-309556-xv3413k1	88	28	human	human	JJ
cord-309556-xv3413k1	88	29	lung	lung	NN
cord-309556-xv3413k1	88	30	.	.	.
cord-309556-xv3413k1	89	1	We	-PRON-	PRP
cord-309556-xv3413k1	89	2	then	then	RB
cord-309556-xv3413k1	89	3	investigated	investigate	VBD
cord-309556-xv3413k1	89	4	whether	whether	IN
cord-309556-xv3413k1	89	5	age	age	NN
cord-309556-xv3413k1	89	6	-	-	HYPH
cord-309556-xv3413k1	89	7	associated	associate	VBN
cord-309556-xv3413k1	89	8	genes	gene	NNS
cord-309556-xv3413k1	89	9	in	in	IN
cord-309556-xv3413k1	89	10	the	the	DT
cord-309556-xv3413k1	89	11	human	human	JJ
cord-309556-xv3413k1	89	12	lung	lung	NN
cord-309556-xv3413k1	89	13	interact	interact	VBP
cord-309556-xv3413k1	89	14	with	with	IN
cord-309556-xv3413k1	89	15	proteins	protein	NNS
cord-309556-xv3413k1	89	16	encoded	encode	VBN
cord-309556-xv3413k1	89	17	by	by	IN
cord-309556-xv3413k1	89	18	SARS	SARS	NNP
cord-309556-xv3413k1	89	19	-	-	HYPH
cord-309556-xv3413k1	89	20	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	89	21	.	.	.
cord-309556-xv3413k1	90	1	A	a	DT
cord-309556-xv3413k1	90	2	recent	recent	JJ
cord-309556-xv3413k1	90	3	study	study	NN
cord-309556-xv3413k1	90	4	interrogated	interrogate	VBD
cord-309556-xv3413k1	90	5	the	the	DT
cord-309556-xv3413k1	90	6	human	human	JJ
cord-309556-xv3413k1	90	7	host	host	NN
cord-309556-xv3413k1	90	8	factors	factor	NNS
cord-309556-xv3413k1	90	9	that	that	WDT
cord-309556-xv3413k1	90	10	interact	interact	VBP
cord-309556-xv3413k1	90	11	with	with	IN
cord-309556-xv3413k1	90	12	27	27	CD
cord-309556-xv3413k1	90	13	different	different	JJ
cord-309556-xv3413k1	90	14	SARS	SARS	NNP
cord-309556-xv3413k1	90	15	-	-	HYPH
cord-309556-xv3413k1	90	16	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	90	17	proteins	protein	VBZ
cord-309556-xv3413k1	90	18	64	64	CD
cord-309556-xv3413k1	90	19	,	,	,
cord-309556-xv3413k1	90	20	revealing	reveal	VBG
cord-309556-xv3413k1	90	21	the	the	DT
cord-309556-xv3413k1	90	22	SARS	SARS	NNP
cord-309556-xv3413k1	90	23	-	-	HYPH
cord-309556-xv3413k1	90	24	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	90	25	:	:	:
cord-309556-xv3413k1	90	26	Human	human	JJ
cord-309556-xv3413k1	90	27	protein	protein	NN
cord-309556-xv3413k1	90	28	interactome	interactome	NNP
cord-309556-xv3413k1	90	29	in	in	IN
cord-309556-xv3413k1	90	30	cell	cell	NN
cord-309556-xv3413k1	90	31	lines	line	NNS
cord-309556-xv3413k1	90	32	expressing	express	VBG
cord-309556-xv3413k1	90	33	recombinant	recombinant	JJ
cord-309556-xv3413k1	90	34	SARS	SARS	NNP
cord-309556-xv3413k1	90	35	-	-	HYPH
cord-309556-xv3413k1	90	36	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	90	37	proteins	protein	NNS
cord-309556-xv3413k1	90	38	.	.	.
cord-309556-xv3413k1	91	1	By	by	IN
cord-309556-xv3413k1	91	2	cross	cross	NN
cord-309556-xv3413k1	91	3	-	-	JJ
cord-309556-xv3413k1	91	4	referencing	reference	VBG
cord-309556-xv3413k1	91	5	the	the	DT
cord-309556-xv3413k1	91	6	interacting	interact	VBG
cord-309556-xv3413k1	91	7	host	host	NN
cord-309556-xv3413k1	91	8	factors	factor	NNS
cord-309556-xv3413k1	91	9	with	with	IN
cord-309556-xv3413k1	91	10	the	the	DT
cord-309556-xv3413k1	91	11	set	set	NN
cord-309556-xv3413k1	91	12	of	of	IN
cord-309556-xv3413k1	91	13	age	age	NN
cord-309556-xv3413k1	91	14	-	-	HYPH
cord-309556-xv3413k1	91	15	associated	associate	VBN
cord-309556-xv3413k1	91	16	genes	gene	NNS
cord-309556-xv3413k1	91	17	,	,	,
cord-309556-xv3413k1	91	18	we	-PRON-	PRP
cord-309556-xv3413k1	91	19	identified	identify	VBD
cord-309556-xv3413k1	91	20	20	20	CD
cord-309556-xv3413k1	91	21	factors	factor	NNS
cord-309556-xv3413k1	91	22	at	at	IN
cord-309556-xv3413k1	91	23	the	the	DT
cord-309556-xv3413k1	91	24	intersection	intersection	NN
cord-309556-xv3413k1	92	1	(	(	-LRB-
cord-309556-xv3413k1	92	2	Figure	figure	NN
cord-309556-xv3413k1	92	3	  	  	_SP
cord-309556-xv3413k1	92	4	5a	5a	CD
cord-309556-xv3413k1	92	5	)	)	-RRB-
cord-309556-xv3413k1	92	6	.	.	.
cord-309556-xv3413k1	93	1	4	4	CD
cord-309556-xv3413k1	93	2	of	of	IN
cord-309556-xv3413k1	93	3	these	these	DT
cord-309556-xv3413k1	93	4	genes	gene	NNS
cord-309556-xv3413k1	93	5	showed	show	VBD
cord-309556-xv3413k1	93	6	an	an	DT
cord-309556-xv3413k1	93	7	increase	increase	NN
cord-309556-xv3413k1	93	8	in	in	IN
cord-309556-xv3413k1	93	9	expression	expression	NN
cord-309556-xv3413k1	93	10	with	with	IN
cord-309556-xv3413k1	93	11	age	age	NN
cord-309556-xv3413k1	93	12	(	(	-LRB-
cord-309556-xv3413k1	93	13	i.e.	i.e.	FW
cord-309556-xv3413k1	93	14	Cluster	cluster	NN
cord-309556-xv3413k1	93	15	1	1	CD
cord-309556-xv3413k1	93	16	genes	gene	NNS
cord-309556-xv3413k1	93	17	)	)	-RRB-
cord-309556-xv3413k1	93	18	,	,	,
cord-309556-xv3413k1	93	19	while	while	IN
cord-309556-xv3413k1	93	20	16	16	CD
cord-309556-xv3413k1	93	21	decreased	decrease	VBD
cord-309556-xv3413k1	93	22	in	in	IN
cord-309556-xv3413k1	93	23	expression	expression	NN
cord-309556-xv3413k1	93	24	with	with	IN
cord-309556-xv3413k1	93	25	age	age	NN
cord-309556-xv3413k1	93	26	(	(	-LRB-
cord-309556-xv3413k1	93	27	Cluster	cluster	NN
cord-309556-xv3413k1	93	28	2	2	CD
cord-309556-xv3413k1	93	29	genes	gene	NNS
cord-309556-xv3413k1	93	30	)	)	-RRB-
cord-309556-xv3413k1	93	31	.	.	.
cord-309556-xv3413k1	94	1	Mapping	map	VBG
cord-309556-xv3413k1	94	2	these	these	DT
cord-309556-xv3413k1	94	3	factors	factor	NNS
cord-309556-xv3413k1	94	4	to	to	IN
cord-309556-xv3413k1	94	5	their	-PRON-	PRP$
cord-309556-xv3413k1	94	6	interacting	interact	VBG
cord-309556-xv3413k1	94	7	SARS	SARS	NNP
cord-309556-xv3413k1	94	8	-	-	HYPH
cord-309556-xv3413k1	94	9	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	94	10	proteins	protein	NNS
cord-309556-xv3413k1	94	11	,	,	,
cord-309556-xv3413k1	94	12	we	-PRON-	PRP
cord-309556-xv3413k1	94	13	noted	note	VBD
cord-309556-xv3413k1	94	14	that	that	IN
cord-309556-xv3413k1	94	15	the	the	DT
cord-309556-xv3413k1	94	16	age	age	NN
cord-309556-xv3413k1	94	17	-	-	HYPH
cord-309556-xv3413k1	94	18	associated	associate	VBN
cord-309556-xv3413k1	94	19	host	host	NN
cord-309556-xv3413k1	94	20	factors	factor	NNS
cord-309556-xv3413k1	94	21	which	which	WDT
cord-309556-xv3413k1	94	22	interact	interact	VBP
cord-309556-xv3413k1	94	23	with	with	IN
cord-309556-xv3413k1	94	24	M	M	NNP
cord-309556-xv3413k1	94	25	,	,	,
cord-309556-xv3413k1	94	26	Nsp13	Nsp13	NNP
cord-309556-xv3413k1	94	27	,	,	,
cord-309556-xv3413k1	94	28	Nsp1	Nsp1	NNP
cord-309556-xv3413k1	94	29	,	,	,
cord-309556-xv3413k1	94	30	Nsp7	Nsp7	NNP
cord-309556-xv3413k1	94	31	,	,	,
cord-309556-xv3413k1	94	32	Nsp8	Nsp8	NNP
cord-309556-xv3413k1	94	33	,	,	,
cord-309556-xv3413k1	94	34	Orf3a	orf3a	XX
cord-309556-xv3413k1	94	35	,	,	,
cord-309556-xv3413k1	94	36	Orf8	Orf8	NNP
cord-309556-xv3413k1	94	37	,	,	,
cord-309556-xv3413k1	94	38	Orf9c	Orf9c	NNP
cord-309556-xv3413k1	94	39	,	,	,
cord-309556-xv3413k1	94	40	and	and	CC
cord-309556-xv3413k1	94	41	Orf10	Orf10	NNP
cord-309556-xv3413k1	94	42	proteins	protein	NNS
cord-309556-xv3413k1	94	43	generally	generally	RB
cord-309556-xv3413k1	94	44	decrease	decrease	VBP
cord-309556-xv3413k1	94	45	in	in	IN
cord-309556-xv3413k1	94	46	expression	expression	NN
cord-309556-xv3413k1	94	47	with	with	IN
cord-309556-xv3413k1	94	48	aging	age	VBG
cord-309556-xv3413k1	94	49	(	(	-LRB-
cord-309556-xv3413k1	94	50	Figure	figure	NN
cord-309556-xv3413k1	94	51	5b	5b	CD
cord-309556-xv3413k1	94	52	)	)	-RRB-
cord-309556-xv3413k1	94	53	.	.	.
cord-309556-xv3413k1	95	1	However	however	RB
cord-309556-xv3413k1	95	2	,	,	,
cord-309556-xv3413k1	95	3	a	a	DT
cord-309556-xv3413k1	95	4	notable	notable	JJ
cord-309556-xv3413k1	95	5	exception	exception	NN
cord-309556-xv3413k1	95	6	was	be	VBD
cord-309556-xv3413k1	95	7	Nsp12	Nsp12	NNP
cord-309556-xv3413k1	95	8	,	,	,
cord-309556-xv3413k1	95	9	as	as	IN
cord-309556-xv3413k1	95	10	the	the	DT
cord-309556-xv3413k1	95	11	age	age	NN
cord-309556-xv3413k1	95	12	-	-	HYPH
cord-309556-xv3413k1	95	13	associated	associate	VBN
cord-309556-xv3413k1	95	14	hostfactors	hostfactor	NNS
cord-309556-xv3413k1	95	15	that	that	WDT
cord-309556-xv3413k1	95	16	interact	interact	VBP
cord-309556-xv3413k1	95	17	with	with	IN
cord-309556-xv3413k1	95	18	Nsp12	Nsp12	NNP
cord-309556-xv3413k1	95	19	both	both	DT
cord-309556-xv3413k1	95	20	showed	show	VBD
cord-309556-xv3413k1	95	21	increased	increased	JJ
cord-309556-xv3413k1	95	22	expression	expression	NN
cord-309556-xv3413k1	95	23	with	with	IN
cord-309556-xv3413k1	95	24	aging	age	VBG
cord-309556-xv3413k1	95	25	(	(	-LRB-
cord-309556-xv3413k1	95	26	CRTC3	crtc3	NN
cord-309556-xv3413k1	96	1	and	and	CC
cord-309556-xv3413k1	96	2	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	96	3	)	)	-RRB-
cord-309556-xv3413k1	97	1	(	(	-LRB-
cord-309556-xv3413k1	97	2	Figure	figure	NN
cord-309556-xv3413k1	97	3	5c	5c	CD
cord-309556-xv3413k1	97	4	)	)	-RRB-
cord-309556-xv3413k1	97	5	.	.	.
cord-309556-xv3413k1	98	1	Nsp12	Nsp12	NNP
cord-309556-xv3413k1	98	2	encodes	encode	VBZ
cord-309556-xv3413k1	98	3	for	for	IN
cord-309556-xv3413k1	98	4	the	the	DT
cord-309556-xv3413k1	98	5	primary	primary	JJ
cord-309556-xv3413k1	98	6	RNA	RNA	NNP
cord-309556-xv3413k1	98	7	-	-	HYPH
cord-309556-xv3413k1	98	8	dependent	dependent	JJ
cord-309556-xv3413k1	98	9	RNA	RNA	NNP
cord-309556-xv3413k1	98	10	polymerase	polymerase	NN
cord-309556-xv3413k1	98	11	(	(	-LRB-
cord-309556-xv3413k1	98	12	RdRp	RdRp	NNP
cord-309556-xv3413k1	98	13	)	)	-RRB-
cord-309556-xv3413k1	98	14	of	of	IN
cord-309556-xv3413k1	98	15	SARS	SARS	NNP
cord-309556-xv3413k1	98	16	-	-	HYPH
cord-309556-xv3413k1	98	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	98	18	,	,	,
cord-309556-xv3413k1	98	19	and	and	CC
cord-309556-xv3413k1	98	20	is	be	VBZ
cord-309556-xv3413k1	98	21	a	a	DT
cord-309556-xv3413k1	98	22	prime	prime	JJ
cord-309556-xv3413k1	98	23	target	target	NN
cord-309556-xv3413k1	98	24	for	for	IN
cord-309556-xv3413k1	98	25	developing	develop	VBG
cord-309556-xv3413k1	98	26	therapies	therapy	NNS
cord-309556-xv3413k1	98	27	against	against	IN
cord-309556-xv3413k1	98	28	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	98	29	.	.	.
cord-309556-xv3413k1	99	1	The	the	DT
cord-309556-xv3413k1	99	2	observation	observation	NN
cord-309556-xv3413k1	99	3	that	that	WDT
cord-309556-xv3413k1	99	4	CRTC3	crtc3	NN
cord-309556-xv3413k1	99	5	and	and	CC
cord-309556-xv3413k1	99	6	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	99	7	increase	increase	VB
cord-309556-xv3413k1	99	8	in	in	IN
cord-309556-xv3413k1	99	9	expression	expression	NN
cord-309556-xv3413k1	99	10	with	with	IN
cord-309556-xv3413k1	99	11	aging	age	VBG
cord-309556-xv3413k1	99	12	is	be	VBZ
cord-309556-xv3413k1	99	13	intriguing	intriguing	JJ
cord-309556-xv3413k1	99	14	,	,	,
cord-309556-xv3413k1	99	15	as	as	IN
cord-309556-xv3413k1	99	16	these	these	DT
cord-309556-xv3413k1	99	17	genes	gene	NNS
cord-309556-xv3413k1	99	18	may	may	MD
cord-309556-xv3413k1	99	19	be	be	VB
cord-309556-xv3413k1	99	20	related	relate	VBN
cord-309556-xv3413k1	99	21	to	to	IN
cord-309556-xv3413k1	99	22	the	the	DT
cord-309556-xv3413k1	99	23	activity	activity	NN
cord-309556-xv3413k1	99	24	of	of	IN
cord-309556-xv3413k1	99	25	Nsp12	Nsp12	NNP
cord-309556-xv3413k1	99	26	/	/	SYM
cord-309556-xv3413k1	99	27	RdRp	RdRp	NNP
cord-309556-xv3413k1	99	28	in	in	IN
cord-309556-xv3413k1	99	29	host	host	NN
cord-309556-xv3413k1	99	30	cells	cell	NNS
cord-309556-xv3413k1	99	31	.	.	.
cord-309556-xv3413k1	100	1	Of	of	IN
cord-309556-xv3413k1	100	2	note	note	NN
cord-309556-xv3413k1	100	3	,	,	,
cord-309556-xv3413k1	100	4	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	100	5	is	be	VBZ
cord-309556-xv3413k1	100	6	a	a	DT
cord-309556-xv3413k1	100	7	known	know	VBN
cord-309556-xv3413k1	100	8	repressor	repressor	NN
cord-309556-xv3413k1	100	9	of	of	IN
cord-309556-xv3413k1	100	10	cAMP	camp	NN
cord-309556-xv3413k1	100	11	signaling	signal	VBG
cord-309556-xv3413k1	100	12	65	65	CD
cord-309556-xv3413k1	100	13	,	,	,
cord-309556-xv3413k1	100	14	66	66	CD
cord-309556-xv3413k1	100	15	,	,	,
cord-309556-xv3413k1	100	16	and	and	CC
cord-309556-xv3413k1	100	17	cAMP	camp	NN
cord-309556-xv3413k1	100	18	signaling	signal	VBG
cord-309556-xv3413k1	100	19	potently	potently	RB
cord-309556-xv3413k1	100	20	inhibits	inhibit	VBZ
cord-309556-xv3413k1	100	21	contraction	contraction	NN
cord-309556-xv3413k1	100	22	of	of	IN
cord-309556-xv3413k1	100	23	airway	airway	JJ
cord-309556-xv3413k1	100	24	smooth	smooth	JJ
cord-309556-xv3413k1	100	25	muscle	muscle	NN
cord-309556-xv3413k1	100	26	cells	cell	NNS
cord-309556-xv3413k1	100	27	67	67	CD
cord-309556-xv3413k1	100	28	.	.	.
cord-309556-xv3413k1	101	1	Thus	thus	RB
cord-309556-xv3413k1	101	2	,	,	,
cord-309556-xv3413k1	101	3	age	age	NN
cord-309556-xv3413k1	101	4	-	-	HYPH
cord-309556-xv3413k1	101	5	associated	associate	VBN
cord-309556-xv3413k1	101	6	increases	increase	NNS
cord-309556-xv3413k1	101	7	in	in	IN
cord-309556-xv3413k1	101	8	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	101	9	could	could	MD
cord-309556-xv3413k1	101	10	promote	promote	VB
cord-309556-xv3413k1	101	11	smooth	smooth	JJ
cord-309556-xv3413k1	101	12	muscle	muscle	NN
cord-309556-xv3413k1	101	13	contraction	contraction	NN
cord-309556-xv3413k1	101	14	,	,	,
cord-309556-xv3413k1	101	15	which	which	WDT
cord-309556-xv3413k1	101	16	is	be	VBZ
cord-309556-xv3413k1	101	17	concordant	concordant	JJ
cord-309556-xv3413k1	101	18	with	with	IN
cord-309556-xv3413k1	101	19	our	-PRON-	PRP$
cord-309556-xv3413k1	101	20	analyses	analysis	NNS
cord-309556-xv3413k1	101	21	on	on	IN
cord-309556-xv3413k1	101	22	age	age	NN
cord-309556-xv3413k1	101	23	-	-	HYPH
cord-309556-xv3413k1	101	24	associated	associate	VBN
cord-309556-xv3413k1	101	25	gene	gene	NN
cord-309556-xv3413k1	101	26	signatures	signature	NNS
cord-309556-xv3413k1	101	27	in	in	IN
cord-309556-xv3413k1	101	28	the	the	DT
cord-309556-xv3413k1	101	29	lung	lung	NN
cord-309556-xv3413k1	101	30	(	(	-LRB-
cord-309556-xv3413k1	101	31	Figure	figure	NN
cord-309556-xv3413k1	101	32	1e	1e	CD
cord-309556-xv3413k1	101	33	)	)	-RRB-
cord-309556-xv3413k1	101	34	.	.	.
cord-309556-xv3413k1	102	1	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	102	2	might	may	MD
cord-309556-xv3413k1	102	3	possibly	possibly	RB
cord-309556-xv3413k1	102	4	contribute	contribute	VB
cord-309556-xv3413k1	102	5	to	to	IN
cord-309556-xv3413k1	102	6	COVID-19	covid-19	JJ
cord-309556-xv3413k1	102	7	pathology	pathology	NN
cord-309556-xv3413k1	102	8	by	by	IN
cord-309556-xv3413k1	102	9	not	not	RB
cord-309556-xv3413k1	102	10	only	only	RB
cord-309556-xv3413k1	102	11	interacting	interact	VBG
cord-309556-xv3413k1	102	12	with	with	IN
cord-309556-xv3413k1	102	13	SARS	SARS	NNP
cord-309556-xv3413k1	102	14	-	-	HYPH
cord-309556-xv3413k1	102	15	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	102	16	RdRp	RdRp	NNP
cord-309556-xv3413k1	102	17	,	,	,
cord-309556-xv3413k1	102	18	but	but	CC
cord-309556-xv3413k1	102	19	also	also	RB
cord-309556-xv3413k1	102	20	through	through	IN
cord-309556-xv3413k1	102	21	its	-PRON-	PRP$
cord-309556-xv3413k1	102	22	normal	normal	JJ
cord-309556-xv3413k1	102	23	physiologic	physiologic	JJ
cord-309556-xv3413k1	102	24	role	role	NN
cord-309556-xv3413k1	102	25	in	in	IN
cord-309556-xv3413k1	102	26	promoting	promote	VBG
cord-309556-xv3413k1	102	27	smooth	smooth	JJ
cord-309556-xv3413k1	102	28	muscle	muscle	NN
cord-309556-xv3413k1	102	29	contraction	contraction	NN
cord-309556-xv3413k1	102	30	.	.	.
cord-309556-xv3413k1	103	1	To	to	TO
cord-309556-xv3413k1	103	2	assess	assess	VB
cord-309556-xv3413k1	103	3	the	the	DT
cord-309556-xv3413k1	103	4	cell	cell	NN
cord-309556-xv3413k1	103	5	type	type	NN
cord-309556-xv3413k1	103	6	-	-	HYPH
cord-309556-xv3413k1	103	7	specific	specific	JJ
cord-309556-xv3413k1	103	8	expression	expression	NN
cord-309556-xv3413k1	103	9	patterns	pattern	NNS
cord-309556-xv3413k1	103	10	of	of	IN
cord-309556-xv3413k1	103	11	these	these	DT
cord-309556-xv3413k1	103	12	various	various	JJ
cord-309556-xv3413k1	103	13	factors	factor	NNS
cord-309556-xv3413k1	103	14	,	,	,
cord-309556-xv3413k1	103	15	we	-PRON-	PRP
cord-309556-xv3413k1	103	16	further	further	RB
cord-309556-xv3413k1	103	17	analyzed	analyze	VBD
cord-309556-xv3413k1	103	18	the	the	DT
cord-309556-xv3413k1	103	19	lung	lung	NN
cord-309556-xv3413k1	103	20	scRNA	scrna	SYM
cord-309556-xv3413k1	103	21	-	-	HYPH
cord-309556-xv3413k1	103	22	seq	seq	NN
cord-309556-xv3413k1	103	23	data	datum	NNS
cord-309556-xv3413k1	103	24	.	.	.
cord-309556-xv3413k1	104	1	Of	of	IN
cord-309556-xv3413k1	104	2	the	the	DT
cord-309556-xv3413k1	104	3	SARS	SARS	NNP
cord-309556-xv3413k1	104	4	-	-	HYPH
cord-309556-xv3413k1	104	5	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	104	6	interacting	interact	VBG
cord-309556-xv3413k1	104	7	genes	gene	NNS
cord-309556-xv3413k1	104	8	that	that	WDT
cord-309556-xv3413k1	104	9	increase	increase	VBP
cord-309556-xv3413k1	104	10	in	in	IN
cord-309556-xv3413k1	104	11	expression	expression	NN
cord-309556-xv3413k1	104	12	with	with	IN
cord-309556-xv3413k1	104	13	age	age	NN
cord-309556-xv3413k1	104	14	,	,	,
cord-309556-xv3413k1	104	15	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	104	16	was	be	VBD
cord-309556-xv3413k1	104	17	frequently	frequently	RB
cord-309556-xv3413k1	104	18	expressed	express	VBN
cord-309556-xv3413k1	104	19	across	across	IN
cord-309556-xv3413k1	104	20	several	several	JJ
cord-309556-xv3413k1	104	21	populations	population	NNS
cord-309556-xv3413k1	104	22	,	,	,
cord-309556-xv3413k1	104	23	particularly	particularly	RB
cord-309556-xv3413k1	104	24	proliferating	proliferate	VBG
cord-309556-xv3413k1	104	25	immune	immune	JJ
cord-309556-xv3413k1	104	26	populations	population	NNS
cord-309556-xv3413k1	104	27	(	(	-LRB-
cord-309556-xv3413k1	104	28	DC	DC	NNP
cord-309556-xv3413k1	104	29	/	/	SYM
cord-309556-xv3413k1	104	30	monocyte	monocyte	NNP
cord-309556-xv3413k1	104	31	,	,	,
cord-309556-xv3413k1	104	32	T	t	NN
cord-309556-xv3413k1	104	33	cells	cell	NNS
cord-309556-xv3413k1	104	34	,	,	,
cord-309556-xv3413k1	104	35	macrophages	macrophage	NNS
cord-309556-xv3413k1	104	36	)	)	-RRB-
cord-309556-xv3413k1	104	37	,	,	,
cord-309556-xv3413k1	104	38	muscle	muscle	NN
cord-309556-xv3413k1	104	39	cells	cell	NNS
cord-309556-xv3413k1	104	40	,	,	,
cord-309556-xv3413k1	104	41	fibroblasts	fibroblast	NNS
cord-309556-xv3413k1	104	42	,	,	,
cord-309556-xv3413k1	104	43	and	and	CC
cord-309556-xv3413k1	104	44	lymph	lymph	NN
cord-309556-xv3413k1	104	45	vessels	vessel	NNS
cord-309556-xv3413k1	104	46	(	(	-LRB-
cord-309556-xv3413k1	104	47	Figure	figure	NN
cord-309556-xv3413k1	104	48	5d	5d	CD
cord-309556-xv3413k1	104	49	)	)	-RRB-
cord-309556-xv3413k1	104	50	.	.	.
cord-309556-xv3413k1	105	1	MYCBP2	MYCBP2	NNP
cord-309556-xv3413k1	105	2	was	be	VBD
cord-309556-xv3413k1	105	3	also	also	RB
cord-309556-xv3413k1	105	4	expressed	express	VBN
cord-309556-xv3413k1	105	5	in	in	IN
cord-309556-xv3413k1	105	6	21.86	21.86	CD
cord-309556-xv3413k1	105	7	%	%	NN
cord-309556-xv3413k1	105	8	of	of	IN
cord-309556-xv3413k1	105	9	AT2	at2	NN
cord-309556-xv3413k1	105	10	cells	cell	NNS
cord-309556-xv3413k1	105	11	.	.	.
cord-309556-xv3413k1	106	1	CEP68	CEP68	NNP
cord-309556-xv3413k1	106	2	was	be	VBD
cord-309556-xv3413k1	106	3	preferentially	preferentially	RB
cord-309556-xv3413k1	106	4	expressed	express	VBN
cord-309556-xv3413k1	106	5	in	in	IN
cord-309556-xv3413k1	106	6	lymph	lymph	NN
cord-309556-xv3413k1	106	7	vessels	vessel	NNS
cord-309556-xv3413k1	106	8	,	,	,
cord-309556-xv3413k1	106	9	while	while	IN
cord-309556-xv3413k1	106	10	AKAP8L	AKAP8L	NNP
cord-309556-xv3413k1	106	11	and	and	CC
cord-309556-xv3413k1	106	12	CRTC3	CRTC3	NNP
cord-309556-xv3413k1	106	13	showed	show	VBD
cord-309556-xv3413k1	106	14	relatively	relatively	RB
cord-309556-xv3413k1	106	15	uniform	uniform	JJ
cord-309556-xv3413k1	106	16	expression	expression	NN
cord-309556-xv3413k1	106	17	frequencies	frequency	NNS
cord-309556-xv3413k1	106	18	across	across	IN
cord-309556-xv3413k1	106	19	cell	cell	NN
cord-309556-xv3413k1	106	20	types	type	NNS
cord-309556-xv3413k1	106	21	,	,	,
cord-309556-xv3413k1	106	22	including	include	VBG
cord-309556-xv3413k1	106	23	a	a	DT
cord-309556-xv3413k1	106	24	fraction	fraction	NN
cord-309556-xv3413k1	106	25	of	of	IN
cord-309556-xv3413k1	106	26	AT2	at2	NN
cord-309556-xv3413k1	106	27	cells	cell	NNS
cord-309556-xv3413k1	106	28	(	(	-LRB-
cord-309556-xv3413k1	106	29	8.53	8.53	CD
cord-309556-xv3413k1	106	30	%	%	NN
cord-309556-xv3413k1	106	31	and	and	CC
cord-309556-xv3413k1	106	32	9.07	9.07	CD
cord-309556-xv3413k1	106	33	%	%	NN
cord-309556-xv3413k1	106	34	expressing	express	VBG
cord-309556-xv3413k1	106	35	cells	cell	NNS
cord-309556-xv3413k1	106	36	,	,	,
cord-309556-xv3413k1	106	37	respectively	respectively	RB
cord-309556-xv3413k1	106	38	)	)	-RRB-
cord-309556-xv3413k1	106	39	.	.	.
cord-309556-xv3413k1	107	1	Of	of	IN
cord-309556-xv3413k1	107	2	the	the	DT
cord-309556-xv3413k1	107	3	SARS	SARS	NNP
cord-309556-xv3413k1	107	4	-	-	HYPH
cord-309556-xv3413k1	107	5	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	107	6	interacting	interact	VBG
cord-309556-xv3413k1	107	7	genes	gene	NNS
cord-309556-xv3413k1	107	8	that	that	WDT
cord-309556-xv3413k1	107	9	decrease	decrease	VBP
cord-309556-xv3413k1	107	10	in	in	IN
cord-309556-xv3413k1	107	11	expression	expression	NN
cord-309556-xv3413k1	107	12	age	age	NN
cord-309556-xv3413k1	107	13	,	,	,
cord-309556-xv3413k1	107	14	NPC2	NPC2	NNP
cord-309556-xv3413k1	107	15	and	and	CC
cord-309556-xv3413k1	107	16	NDUFB9	ndufb9	JJ
cord-309556-xv3413k1	107	17	were	be	VBD
cord-309556-xv3413k1	107	18	broadly	broadly	RB
cord-309556-xv3413k1	107	19	expressed	express	VBN
cord-309556-xv3413k1	107	20	in	in	IN
cord-309556-xv3413k1	107	21	many	many	JJ
cord-309556-xv3413k1	107	22	cell	cell	NN
cord-309556-xv3413k1	107	23	types	type	NNS
cord-309556-xv3413k1	107	24	,	,	,
cord-309556-xv3413k1	107	25	including	include	VBG
cord-309556-xv3413k1	107	26	AT2	at2	NN
cord-309556-xv3413k1	107	27	cells	cell	NNS
cord-309556-xv3413k1	107	28	(	(	-LRB-
cord-309556-xv3413k1	107	29	99.96	99.96	CD
cord-309556-xv3413k1	107	30	%	%	NN
cord-309556-xv3413k1	107	31	Together	together	RB
cord-309556-xv3413k1	107	32	,	,	,
cord-309556-xv3413k1	107	33	these	these	DT
cord-309556-xv3413k1	107	34	analyses	analysis	NNS
cord-309556-xv3413k1	107	35	highlight	highlight	VBP
cord-309556-xv3413k1	107	36	specific	specific	JJ
cord-309556-xv3413k1	107	37	age	age	NN
cord-309556-xv3413k1	107	38	-	-	HYPH
cord-309556-xv3413k1	107	39	associated	associate	VBN
cord-309556-xv3413k1	107	40	factors	factor	NNS
cord-309556-xv3413k1	107	41	that	that	WDT
cord-309556-xv3413k1	107	42	interact	interact	VBP
cord-309556-xv3413k1	107	43	with	with	IN
cord-309556-xv3413k1	107	44	the	the	DT
cord-309556-xv3413k1	107	45	SARS	SARS	NNP
cord-309556-xv3413k1	107	46	-	-	HYPH
cord-309556-xv3413k1	107	47	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	107	48	proteome	proteome	NN
cord-309556-xv3413k1	107	49	,	,	,
cord-309556-xv3413k1	107	50	in	in	IN
cord-309556-xv3413k1	107	51	the	the	DT
cord-309556-xv3413k1	107	52	context	context	NN
cord-309556-xv3413k1	107	53	of	of	IN
cord-309556-xv3413k1	107	54	the	the	DT
cord-309556-xv3413k1	107	55	lung	lung	NN
cord-309556-xv3413k1	107	56	cell	cell	NN
cord-309556-xv3413k1	107	57	types	type	NNS
cord-309556-xv3413k1	107	58	in	in	IN
cord-309556-xv3413k1	107	59	which	which	WDT
cord-309556-xv3413k1	107	60	these	these	DT
cord-309556-xv3413k1	107	61	factors	factor	NNS
cord-309556-xv3413k1	107	62	are	be	VBP
cord-309556-xv3413k1	107	63	normally	normally	RB
cord-309556-xv3413k1	107	64	expressed	express	VBN
cord-309556-xv3413k1	107	65	.	.	.
cord-309556-xv3413k1	108	1	Finally	finally	RB
cord-309556-xv3413k1	108	2	,	,	,
cord-309556-xv3413k1	108	3	we	-PRON-	PRP
cord-309556-xv3413k1	108	4	assessed	assess	VBD
cord-309556-xv3413k1	108	5	whether	whether	IN
cord-309556-xv3413k1	108	6	SARS	SARS	NNP
cord-309556-xv3413k1	108	7	-	-	HYPH
cord-309556-xv3413k1	108	8	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	108	9	infection	infection	NN
cord-309556-xv3413k1	108	10	directly	directly	RB
cord-309556-xv3413k1	108	11	alters	alter	VBZ
cord-309556-xv3413k1	108	12	the	the	DT
cord-309556-xv3413k1	108	13	expression	expression	NN
cord-309556-xv3413k1	108	14	of	of	IN
cord-309556-xv3413k1	108	15	lung	lung	NN
cord-309556-xv3413k1	108	16	ageassociated	ageassociate	VBN
cord-309556-xv3413k1	108	17	genes	gene	NNS
cord-309556-xv3413k1	108	18	.	.	.
cord-309556-xv3413k1	109	1	A	a	DT
cord-309556-xv3413k1	109	2	recent	recent	JJ
cord-309556-xv3413k1	109	3	study	study	NN
cord-309556-xv3413k1	109	4	profiled	profile	VBD
cord-309556-xv3413k1	109	5	the	the	DT
cord-309556-xv3413k1	109	6	in	in	FW
cord-309556-xv3413k1	109	7	vitro	vitro	FW
cord-309556-xv3413k1	109	8	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	109	9	changes	change	NNS
cord-309556-xv3413k1	109	10	associated	associate	VBN
cord-309556-xv3413k1	109	11	with	with	IN
cord-309556-xv3413k1	109	12	SARS	SARS	NNP
cord-309556-xv3413k1	109	13	-	-	HYPH
cord-309556-xv3413k1	109	14	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	109	15	infection	infection	NN
cord-309556-xv3413k1	109	16	in	in	IN
cord-309556-xv3413k1	109	17	different	different	JJ
cord-309556-xv3413k1	109	18	human	human	JJ
cord-309556-xv3413k1	109	19	lung	lung	NN
cord-309556-xv3413k1	109	20	cell	cell	NN
cord-309556-xv3413k1	109	21	lines	line	NNS
cord-309556-xv3413k1	109	22	68	68	CD
cord-309556-xv3413k1	109	23	.	.	.
cord-309556-xv3413k1	110	1	We	-PRON-	PRP
cord-309556-xv3413k1	110	2	specifically	specifically	RB
cord-309556-xv3413k1	110	3	focused	focus	VBD
cord-309556-xv3413k1	110	4	on	on	IN
cord-309556-xv3413k1	110	5	the	the	DT
cord-309556-xv3413k1	110	6	data	datum	NNS
cord-309556-xv3413k1	110	7	from	from	IN
cord-309556-xv3413k1	110	8	A549	a549	JJ
cord-309556-xv3413k1	110	9	lung	lung	NN
cord-309556-xv3413k1	110	10	cancer	cancer	NN
cord-309556-xv3413k1	110	11	cells	cell	NNS
cord-309556-xv3413k1	110	12	,	,	,
cord-309556-xv3413k1	110	13	A549	a549	JJ
cord-309556-xv3413k1	110	14	cells	cell	NNS
cord-309556-xv3413k1	110	15	transduced	transduce	VBN
cord-309556-xv3413k1	110	16	with	with	IN
cord-309556-xv3413k1	110	17	an	an	DT
cord-309556-xv3413k1	110	18	ACE2	ACE2	NNP
cord-309556-xv3413k1	110	19	expression	expression	NN
cord-309556-xv3413k1	110	20	vector	vector	NN
cord-309556-xv3413k1	110	21	(	(	-LRB-
cord-309556-xv3413k1	110	22	A549-ACE2	A549-ACE2	NNP
cord-309556-xv3413k1	110	23	)	)	-RRB-
cord-309556-xv3413k1	110	24	,	,	,
cord-309556-xv3413k1	110	25	and	and	CC
cord-309556-xv3413k1	110	26	Calu-3	Calu-3	NNP
cord-309556-xv3413k1	110	27	lung	lung	NN
cord-309556-xv3413k1	110	28	cancer	cancer	NN
cord-309556-xv3413k1	110	29	cells	cell	NNS
cord-309556-xv3413k1	110	30	.	.	.
cord-309556-xv3413k1	111	1	Several	several	JJ
cord-309556-xv3413k1	111	2	age	age	NN
cord-309556-xv3413k1	111	3	-	-	HYPH
cord-309556-xv3413k1	111	4	associated	associate	VBN
cord-309556-xv3413k1	111	5	genes	gene	NNS
cord-309556-xv3413k1	111	6	were	be	VBD
cord-309556-xv3413k1	111	7	found	find	VBN
cord-309556-xv3413k1	111	8	to	to	TO
cord-309556-xv3413k1	111	9	be	be	VB
cord-309556-xv3413k1	111	10	differentially	differentially	RB
cord-309556-xv3413k1	111	11	expressed	express	VBN
cord-309556-xv3413k1	111	12	upon	upon	IN
cord-309556-xv3413k1	111	13	SARS	SARS	NNP
cord-309556-xv3413k1	111	14	-	-	HYPH
cord-309556-xv3413k1	111	15	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	111	16	infection	infection	NN
cord-309556-xv3413k1	111	17	(	(	-LRB-
cord-309556-xv3413k1	111	18	Figure	figure	NN
cord-309556-xv3413k1	111	19	6a	6a	CD
cord-309556-xv3413k1	111	20	-	-	HYPH
cord-309556-xv3413k1	111	21	c	c	NN
cord-309556-xv3413k1	111	22	)	)	-RRB-
cord-309556-xv3413k1	111	23	.	.	.
cord-309556-xv3413k1	112	1	Of	of	IN
cord-309556-xv3413k1	112	2	note	note	NN
cord-309556-xv3413k1	112	3	,	,	,
cord-309556-xv3413k1	112	4	the	the	DT
cord-309556-xv3413k1	112	5	overlap	overlap	NN
cord-309556-xv3413k1	112	6	between	between	IN
cord-309556-xv3413k1	112	7	lung	lung	NN
cord-309556-xv3413k1	112	8	ageassociated	ageassociate	VBN
cord-309556-xv3413k1	112	9	genes	gene	NNS
cord-309556-xv3413k1	112	10	and	and	CC
cord-309556-xv3413k1	112	11	SARS	SARS	NNP
cord-309556-xv3413k1	112	12	-	-	HYPH
cord-309556-xv3413k1	112	13	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	112	14	regulated	regulate	VBN
cord-309556-xv3413k1	112	15	genes	gene	NNS
cord-309556-xv3413k1	112	16	was	be	VBD
cord-309556-xv3413k1	112	17	statistically	statistically	RB
cord-309556-xv3413k1	112	18	significant	significant	JJ
cord-309556-xv3413k1	112	19	across	across	IN
cord-309556-xv3413k1	112	20	all	all	DT
cord-309556-xv3413k1	112	21	3	3	CD
cord-309556-xv3413k1	112	22	cell	cell	NN
cord-309556-xv3413k1	112	23	lines	line	NNS
cord-309556-xv3413k1	112	24	(	(	-LRB-
cord-309556-xv3413k1	112	25	Figure	Figure	NNP
cord-309556-xv3413k1	112	26	6d	6d	NNP
cord-309556-xv3413k1	112	27	-	-	HYPH
cord-309556-xv3413k1	112	28	f	f	NNP
cord-309556-xv3413k1	112	29	)	)	-RRB-
cord-309556-xv3413k1	112	30	,	,	,
cord-309556-xv3413k1	112	31	suggesting	suggest	VBG
cord-309556-xv3413k1	112	32	a	a	DT
cord-309556-xv3413k1	112	33	degree	degree	NN
cord-309556-xv3413k1	112	34	of	of	IN
cord-309556-xv3413k1	112	35	similarity	similarity	NN
cord-309556-xv3413k1	112	36	between	between	IN
cord-309556-xv3413k1	112	37	the	the	DT
cord-309556-xv3413k1	112	38	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	112	39	changes	change	NNS
cord-309556-xv3413k1	112	40	associated	associate	VBN
cord-309556-xv3413k1	112	41	with	with	IN
cord-309556-xv3413k1	112	42	aging	age	VBG
cord-309556-xv3413k1	112	43	and	and	CC
cord-309556-xv3413k1	112	44	with	with	IN
cord-309556-xv3413k1	112	45	SARS	SARS	NNP
cord-309556-xv3413k1	112	46	-	-	HYPH
cord-309556-xv3413k1	112	47	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	112	48	infection	infection	NN
cord-309556-xv3413k1	112	49	.	.	.
cord-309556-xv3413k1	113	1	Among	among	IN
cord-309556-xv3413k1	113	2	the	the	DT
cord-309556-xv3413k1	113	3	age	age	NN
cord-309556-xv3413k1	113	4	-	-	HYPH
cord-309556-xv3413k1	113	5	associated	associate	VBN
cord-309556-xv3413k1	113	6	genes	gene	NNS
cord-309556-xv3413k1	113	7	that	that	WDT
cord-309556-xv3413k1	113	8	were	be	VBD
cord-309556-xv3413k1	113	9	induced	induce	VBN
cord-309556-xv3413k1	113	10	by	by	IN
cord-309556-xv3413k1	113	11	SARS	SARS	NNP
cord-309556-xv3413k1	113	12	-	-	HYPH
cord-309556-xv3413k1	113	13	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	113	14	infection	infection	NN
cord-309556-xv3413k1	113	15	,	,	,
cord-309556-xv3413k1	113	16	the	the	DT
cord-309556-xv3413k1	113	17	majority	majority	NN
cord-309556-xv3413k1	113	18	of	of	IN
cord-309556-xv3413k1	113	19	these	these	DT
cord-309556-xv3413k1	113	20	genes	gene	NNS
cord-309556-xv3413k1	113	21	increase	increase	VBP
cord-309556-xv3413k1	113	22	in	in	IN
cord-309556-xv3413k1	113	23	expression	expression	NN
cord-309556-xv3413k1	113	24	with	with	IN
cord-309556-xv3413k1	113	25	age	age	NN
cord-309556-xv3413k1	113	26	(	(	-LRB-
cord-309556-xv3413k1	113	27	Cluster	cluster	NN
cord-309556-xv3413k1	113	28	1	1	CD
cord-309556-xv3413k1	113	29	)	)	-RRB-
cord-309556-xv3413k1	113	30	(	(	-LRB-
cord-309556-xv3413k1	113	31	Figure	figure	NN
cord-309556-xv3413k1	113	32	6g	6g	NN
cord-309556-xv3413k1	113	33	-	-	:
cord-309556-xv3413k1	113	34	i	i	NN
cord-309556-xv3413k1	113	35	)	)	-RRB-
cord-309556-xv3413k1	113	36	.	.	.
cord-309556-xv3413k1	114	1	Conversely	conversely	RB
cord-309556-xv3413k1	114	2	,	,	,
cord-309556-xv3413k1	114	3	among	among	IN
cord-309556-xv3413k1	114	4	the	the	DT
cord-309556-xv3413k1	114	5	age	age	NN
cord-309556-xv3413k1	114	6	-	-	HYPH
cord-309556-xv3413k1	114	7	associated	associate	VBN
cord-309556-xv3413k1	114	8	genes	gene	NNS
cord-309556-xv3413k1	114	9	that	that	WDT
cord-309556-xv3413k1	114	10	were	be	VBD
cord-309556-xv3413k1	114	11	repressed	repress	VBN
cord-309556-xv3413k1	114	12	by	by	IN
cord-309556-xv3413k1	114	13	SARS	SARS	NNP
cord-309556-xv3413k1	114	14	-	-	HYPH
cord-309556-xv3413k1	114	15	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	114	16	infection	infection	NN
cord-309556-xv3413k1	114	17	,	,	,
cord-309556-xv3413k1	114	18	most	most	JJS
cord-309556-xv3413k1	114	19	of	of	IN
cord-309556-xv3413k1	114	20	these	these	DT
cord-309556-xv3413k1	114	21	genes	gene	NNS
cord-309556-xv3413k1	114	22	decrease	decrease	VBP
cord-309556-xv3413k1	114	23	in	in	IN
cord-309556-xv3413k1	114	24	expression	expression	NN
cord-309556-xv3413k1	114	25	with	with	IN
cord-309556-xv3413k1	114	26	age	age	NN
cord-309556-xv3413k1	114	27	(	(	-LRB-
cord-309556-xv3413k1	114	28	Cluster	cluster	NN
cord-309556-xv3413k1	114	29	2	2	CD
cord-309556-xv3413k1	114	30	)	)	-RRB-
cord-309556-xv3413k1	114	31	.	.	.
cord-309556-xv3413k1	115	1	Of	of	IN
cord-309556-xv3413k1	115	2	note	note	NN
cord-309556-xv3413k1	115	3	,	,	,
cord-309556-xv3413k1	115	4	the	the	DT
cord-309556-xv3413k1	115	5	directionality	directionality	NN
cord-309556-xv3413k1	115	6	of	of	IN
cord-309556-xv3413k1	115	7	SARS	SARS	NNP
cord-309556-xv3413k1	115	8	-	-	HYPH
cord-309556-xv3413k1	115	9	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	115	10	regulation	regulation	NN
cord-309556-xv3413k1	115	11	(	(	-LRB-
cord-309556-xv3413k1	115	12	induced	induce	VBN
cord-309556-xv3413k1	115	13	or	or	CC
cord-309556-xv3413k1	115	14	repressed	repress	VBN
cord-309556-xv3413k1	115	15	)	)	-RRB-
cord-309556-xv3413k1	115	16	and	and	CC
cord-309556-xv3413k1	115	17	the	the	DT
cord-309556-xv3413k1	115	18	directionality	directionality	NN
cord-309556-xv3413k1	115	19	of	of	IN
cord-309556-xv3413k1	115	20	ageassociation	ageassociation	NN
cord-309556-xv3413k1	115	21	(	(	-LRB-
cord-309556-xv3413k1	115	22	increase	increase	NN
cord-309556-xv3413k1	115	23	or	or	CC
cord-309556-xv3413k1	115	24	decrease	decrease	VB
cord-309556-xv3413k1	115	25	with	with	IN
cord-309556-xv3413k1	115	26	age	age	NN
cord-309556-xv3413k1	115	27	)	)	-RRB-
cord-309556-xv3413k1	115	28	were	be	VBD
cord-309556-xv3413k1	115	29	significantly	significantly	RB
cord-309556-xv3413k1	115	30	associated	associate	VBN
cord-309556-xv3413k1	115	31	across	across	IN
cord-309556-xv3413k1	115	32	all	all	DT
cord-309556-xv3413k1	115	33	3	3	CD
cord-309556-xv3413k1	115	34	cell	cell	NN
cord-309556-xv3413k1	115	35	lines	line	NNS
cord-309556-xv3413k1	115	36	(	(	-LRB-
cord-309556-xv3413k1	115	37	Figure	figure	NN
cord-309556-xv3413k1	115	38	6g	6g	NNPS
cord-309556-xv3413k1	115	39	-	-	:
cord-309556-xv3413k1	115	40	i	i	NN
cord-309556-xv3413k1	115	41	)	)	-RRB-
cord-309556-xv3413k1	115	42	.	.	.
cord-309556-xv3413k1	116	1	To	to	TO
cord-309556-xv3413k1	116	2	identify	identify	VB
cord-309556-xv3413k1	116	3	a	a	DT
cord-309556-xv3413k1	116	4	consensus	consensus	NN
cord-309556-xv3413k1	116	5	set	set	VBN
cord-309556-xv3413k1	116	6	of	of	IN
cord-309556-xv3413k1	116	7	age	age	NN
cord-309556-xv3413k1	116	8	-	-	HYPH
cord-309556-xv3413k1	116	9	associated	associate	VBN
cord-309556-xv3413k1	116	10	genes	gene	NNS
cord-309556-xv3413k1	116	11	that	that	WDT
cord-309556-xv3413k1	116	12	are	be	VBP
cord-309556-xv3413k1	116	13	regulated	regulate	VBN
cord-309556-xv3413k1	116	14	by	by	IN
cord-309556-xv3413k1	116	15	SARS	SARS	NNP
cord-309556-xv3413k1	116	16	-	-	HYPH
cord-309556-xv3413k1	116	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	116	18	infection	infection	NN
cord-309556-xv3413k1	116	19	,	,	,
cord-309556-xv3413k1	116	20	we	-PRON-	PRP
cord-309556-xv3413k1	116	21	integrated	integrate	VBD
cord-309556-xv3413k1	116	22	the	the	DT
cord-309556-xv3413k1	116	23	analyses	analysis	NNS
cord-309556-xv3413k1	116	24	from	from	IN
cord-309556-xv3413k1	116	25	all	all	DT
cord-309556-xv3413k1	116	26	3	3	CD
cord-309556-xv3413k1	116	27	cell	cell	NN
cord-309556-xv3413k1	116	28	lines	line	NNS
cord-309556-xv3413k1	116	29	.	.	.
cord-309556-xv3413k1	117	1	603	603	CD
cord-309556-xv3413k1	117	2	genes	gene	NNS
cord-309556-xv3413k1	117	3	were	be	VBD
cord-309556-xv3413k1	117	4	consistently	consistently	RB
cord-309556-xv3413k1	117	5	induced	induce	VBN
cord-309556-xv3413k1	117	6	by	by	IN
cord-309556-xv3413k1	117	7	SARS	SARS	NNP
cord-309556-xv3413k1	117	8	-	-	HYPH
cord-309556-xv3413k1	117	9	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	117	10	infection	infection	NN
cord-309556-xv3413k1	117	11	(	(	-LRB-
cord-309556-xv3413k1	117	12	Figure	figure	NN
cord-309556-xv3413k1	117	13	7a	7a	NN
cord-309556-xv3413k1	117	14	)	)	-RRB-
cord-309556-xv3413k1	117	15	.	.	.
cord-309556-xv3413k1	118	1	Of	of	IN
cord-309556-xv3413k1	118	2	these	these	DT
cord-309556-xv3413k1	118	3	,	,	,
cord-309556-xv3413k1	118	4	20	20	CD
cord-309556-xv3413k1	118	5	genes	gene	NNS
cord-309556-xv3413k1	118	6	are	be	VBP
cord-309556-xv3413k1	118	7	in	in	IN
cord-309556-xv3413k1	118	8	Cluster	cluster	NN
cord-309556-xv3413k1	118	9	1	1	CD
cord-309556-xv3413k1	118	10	(	(	-LRB-
cord-309556-xv3413k1	118	11	increase	increase	NN
cord-309556-xv3413k1	118	12	with	with	IN
cord-309556-xv3413k1	118	13	age	age	NN
cord-309556-xv3413k1	118	14	)	)	-RRB-
cord-309556-xv3413k1	118	15	and	and	CC
cord-309556-xv3413k1	118	16	2	2	CD
cord-309556-xv3413k1	118	17	genes	gene	NNS
cord-309556-xv3413k1	118	18	are	be	VBP
cord-309556-xv3413k1	118	19	in	in	IN
cord-309556-xv3413k1	118	20	Cluster	cluster	NN
cord-309556-xv3413k1	118	21	2	2	CD
cord-309556-xv3413k1	118	22	(	(	-LRB-
cord-309556-xv3413k1	118	23	decrease	decrease	NN
cord-309556-xv3413k1	118	24	with	with	IN
cord-309556-xv3413k1	118	25	age	age	NN
cord-309556-xv3413k1	118	26	)	)	-RRB-
cord-309556-xv3413k1	118	27	.	.	.
cord-309556-xv3413k1	119	1	The	the	DT
cord-309556-xv3413k1	119	2	20	20	CD
cord-309556-xv3413k1	119	3	induced	induce	VBN
cord-309556-xv3413k1	119	4	genes	gene	NNS
cord-309556-xv3413k1	119	5	in	in	IN
cord-309556-xv3413k1	119	6	Cluster	cluster	NN
cord-309556-xv3413k1	119	7	1	1	CD
cord-309556-xv3413k1	119	8	include	include	VBP
cord-309556-xv3413k1	119	9	several	several	JJ
cord-309556-xv3413k1	119	10	factors	factor	NNS
cord-309556-xv3413k1	119	11	involved	involve	VBN
cord-309556-xv3413k1	119	12	in	in	IN
cord-309556-xv3413k1	119	13	RAS	RAS	NNP
cord-309556-xv3413k1	119	14	signaling	signal	VBG
cord-309556-xv3413k1	119	15	(	(	-LRB-
cord-309556-xv3413k1	119	16	RAB8B	RAB8B	NNP
cord-309556-xv3413k1	119	17	,	,	,
cord-309556-xv3413k1	119	18	RASA2	RASA2	NNS
cord-309556-xv3413k1	119	19	,	,	,
cord-309556-xv3413k1	119	20	and	and	CC
cord-309556-xv3413k1	119	21	RASGRP1	RASGRP1	NNP
cord-309556-xv3413k1	119	22	)	)	-RRB-
cord-309556-xv3413k1	119	23	as	as	RB
cord-309556-xv3413k1	119	24	well	well	RB
cord-309556-xv3413k1	119	25	as	as	IN
cord-309556-xv3413k1	119	26	CLK1	CLK1	NNP
cord-309556-xv3413k1	119	27	,	,	,
cord-309556-xv3413k1	119	28	which	which	WDT
cord-309556-xv3413k1	119	29	was	be	VBD
cord-309556-xv3413k1	119	30	shown	show	VBN
cord-309556-xv3413k1	119	31	to	to	TO
cord-309556-xv3413k1	119	32	be	be	VB
cord-309556-xv3413k1	119	33	involved	involve	VBN
cord-309556-xv3413k1	119	34	in	in	IN
cord-309556-xv3413k1	119	35	host	host	NN
cord-309556-xv3413k1	119	36	responses	response	NNS
cord-309556-xv3413k1	119	37	to	to	IN
cord-309556-xv3413k1	119	38	SARS	SARS	NNP
cord-309556-xv3413k1	119	39	-	-	HYPH
cord-309556-xv3413k1	119	40	CoV	CoV	NNP
cord-309556-xv3413k1	119	41	infection	infection	NN
cord-309556-xv3413k1	119	42	(	(	-LRB-
cord-309556-xv3413k1	119	43	Figure	figure	NN
cord-309556-xv3413k1	119	44	4a	4a	CD
cord-309556-xv3413k1	119	45	-	-	HYPH
cord-309556-xv3413k1	119	46	b	b	NN
cord-309556-xv3413k1	119	47	)	)	-RRB-
cord-309556-xv3413k1	119	48	.	.	.
cord-309556-xv3413k1	120	1	On	on	IN
cord-309556-xv3413k1	120	2	the	the	DT
cord-309556-xv3413k1	120	3	other	other	JJ
cord-309556-xv3413k1	120	4	hand	hand	NN
cord-309556-xv3413k1	120	5	,	,	,
cord-309556-xv3413k1	120	6	641	641	CD
cord-309556-xv3413k1	120	7	genes	gene	NNS
cord-309556-xv3413k1	120	8	were	be	VBD
cord-309556-xv3413k1	120	9	concordantly	concordantly	RB
cord-309556-xv3413k1	120	10	repressed	repress	VBN
cord-309556-xv3413k1	120	11	by	by	IN
cord-309556-xv3413k1	120	12	SARS	SARS	NNP
cord-309556-xv3413k1	120	13	-	-	HYPH
cord-309556-xv3413k1	120	14	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	120	15	infection	infection	NN
cord-309556-xv3413k1	120	16	(	(	-LRB-
cord-309556-xv3413k1	120	17	Figure	figure	NN
cord-309556-xv3413k1	120	18	7b	7b	NN
cord-309556-xv3413k1	120	19	 	 	_SP
cord-309556-xv3413k1	121	1	Here	here	RB
cord-309556-xv3413k1	121	2	we	-PRON-	PRP
cord-309556-xv3413k1	121	3	systematically	systematically	RB
cord-309556-xv3413k1	121	4	analyzed	analyze	VBD
cord-309556-xv3413k1	121	5	the	the	DT
cord-309556-xv3413k1	121	6	transcriptome	transcriptome	NN
cord-309556-xv3413k1	121	7	of	of	IN
cord-309556-xv3413k1	121	8	the	the	DT
cord-309556-xv3413k1	121	9	aging	age	VBG
cord-309556-xv3413k1	121	10	human	human	JJ
cord-309556-xv3413k1	121	11	lung	lung	NN
cord-309556-xv3413k1	121	12	and	and	CC
cord-309556-xv3413k1	121	13	its	-PRON-	PRP$
cord-309556-xv3413k1	121	14	relationship	relationship	NN
cord-309556-xv3413k1	121	15	to	to	IN
cord-309556-xv3413k1	121	16	SARS	SARS	NNP
cord-309556-xv3413k1	121	17	-	-	HYPH
cord-309556-xv3413k1	121	18	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	121	19	.	.	.
cord-309556-xv3413k1	122	1	We	-PRON-	PRP
cord-309556-xv3413k1	122	2	found	find	VBD
cord-309556-xv3413k1	122	3	that	that	IN
cord-309556-xv3413k1	122	4	the	the	DT
cord-309556-xv3413k1	122	5	aging	age	VBG
cord-309556-xv3413k1	122	6	lung	lung	NN
cord-309556-xv3413k1	122	7	is	be	VBZ
cord-309556-xv3413k1	122	8	characterized	characterize	VBN
cord-309556-xv3413k1	122	9	by	by	IN
cord-309556-xv3413k1	122	10	a	a	DT
cord-309556-xv3413k1	122	11	wide	wide	JJ
cord-309556-xv3413k1	122	12	array	array	NN
cord-309556-xv3413k1	122	13	of	of	IN
cord-309556-xv3413k1	122	14	changes	change	NNS
cord-309556-xv3413k1	122	15	that	that	WDT
cord-309556-xv3413k1	122	16	could	could	MD
cord-309556-xv3413k1	122	17	contribute	contribute	VB
cord-309556-xv3413k1	122	18	to	to	IN
cord-309556-xv3413k1	122	19	the	the	DT
cord-309556-xv3413k1	122	20	worse	bad	JJR
cord-309556-xv3413k1	122	21	outcomes	outcome	NNS
cord-309556-xv3413k1	122	22	of	of	IN
cord-309556-xv3413k1	122	23	older	old	JJR
cord-309556-xv3413k1	122	24	patients	patient	NNS
cord-309556-xv3413k1	122	25	with	with	IN
cord-309556-xv3413k1	122	26	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	122	27	.	.	.
cord-309556-xv3413k1	123	1	On	on	IN
cord-309556-xv3413k1	123	2	the	the	DT
cord-309556-xv3413k1	123	3	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	123	4	level	level	NN
cord-309556-xv3413k1	123	5	,	,	,
cord-309556-xv3413k1	123	6	we	-PRON-	PRP
cord-309556-xv3413k1	123	7	first	first	RB
cord-309556-xv3413k1	123	8	identified	identify	VBD
cord-309556-xv3413k1	123	9	1,285	1,285	CD
cord-309556-xv3413k1	123	10	genes	gene	NNS
cord-309556-xv3413k1	123	11	that	that	WDT
cord-309556-xv3413k1	123	12	exhibit	exhibit	VBP
cord-309556-xv3413k1	123	13	age	age	NN
cord-309556-xv3413k1	123	14	-	-	HYPH
cord-309556-xv3413k1	123	15	associated	associate	VBN
cord-309556-xv3413k1	123	16	expression	expression	NN
cord-309556-xv3413k1	123	17	patterns	pattern	NNS
cord-309556-xv3413k1	123	18	.	.	.
cord-309556-xv3413k1	124	1	We	-PRON-	PRP
cord-309556-xv3413k1	124	2	subsequently	subsequently	RB
cord-309556-xv3413k1	124	3	demonstrated	demonstrate	VBD
cord-309556-xv3413k1	124	4	that	that	IN
cord-309556-xv3413k1	124	5	the	the	DT
cord-309556-xv3413k1	124	6	aging	age	VBG
cord-309556-xv3413k1	124	7	lung	lung	NN
cord-309556-xv3413k1	124	8	is	be	VBZ
cord-309556-xv3413k1	124	9	characterized	characterize	VBN
cord-309556-xv3413k1	124	10	by	by	IN
cord-309556-xv3413k1	124	11	several	several	JJ
cord-309556-xv3413k1	124	12	gene	gene	NN
cord-309556-xv3413k1	124	13	signatures	signature	NNS
cord-309556-xv3413k1	124	14	,	,	,
cord-309556-xv3413k1	124	15	including	include	VBG
cord-309556-xv3413k1	124	16	increased	increase	VBN
cord-309556-xv3413k1	124	17	vascular	vascular	JJ
cord-309556-xv3413k1	124	18	smooth	smooth	JJ
cord-309556-xv3413k1	124	19	muscle	muscle	NN
cord-309556-xv3413k1	124	20	contraction	contraction	NN
cord-309556-xv3413k1	124	21	,	,	,
cord-309556-xv3413k1	124	22	reduced	reduce	VBN
cord-309556-xv3413k1	124	23	mitochondrial	mitochondrial	JJ
cord-309556-xv3413k1	124	24	activity	activity	NN
cord-309556-xv3413k1	124	25	,	,	,
cord-309556-xv3413k1	124	26	and	and	CC
cord-309556-xv3413k1	124	27	decreased	decrease	VBD
cord-309556-xv3413k1	124	28	lipid	lipid	NN
cord-309556-xv3413k1	124	29	metabolism	metabolism	NN
cord-309556-xv3413k1	124	30	.	.	.
cord-309556-xv3413k1	125	1	By	by	IN
cord-309556-xv3413k1	125	2	integrating	integrate	VBG
cord-309556-xv3413k1	125	3	these	these	DT
cord-309556-xv3413k1	125	4	data	datum	NNS
cord-309556-xv3413k1	125	5	with	with	IN
cord-309556-xv3413k1	125	6	single	single	JJ
cord-309556-xv3413k1	125	7	cell	cell	NN
cord-309556-xv3413k1	125	8	transcriptomes	transcriptome	NNS
cord-309556-xv3413k1	125	9	of	of	IN
cord-309556-xv3413k1	125	10	human	human	JJ
cord-309556-xv3413k1	125	11	lung	lung	NN
cord-309556-xv3413k1	125	12	tissue	tissue	NN
cord-309556-xv3413k1	125	13	,	,	,
cord-309556-xv3413k1	125	14	we	-PRON-	PRP
cord-309556-xv3413k1	125	15	further	further	RB
cord-309556-xv3413k1	125	16	pinpointed	pinpoint	VBD
cord-309556-xv3413k1	125	17	the	the	DT
cord-309556-xv3413k1	125	18	specific	specific	JJ
cord-309556-xv3413k1	125	19	cell	cell	NN
cord-309556-xv3413k1	125	20	types	type	NNS
cord-309556-xv3413k1	125	21	that	that	WDT
cord-309556-xv3413k1	125	22	normally	normally	RB
cord-309556-xv3413k1	125	23	express	express	VBP
cord-309556-xv3413k1	125	24	the	the	DT
cord-309556-xv3413k1	125	25	age	age	NN
cord-309556-xv3413k1	125	26	-	-	HYPH
cord-309556-xv3413k1	125	27	associated	associate	VBN
cord-309556-xv3413k1	125	28	genes	gene	NNS
cord-309556-xv3413k1	125	29	.	.	.
cord-309556-xv3413k1	126	1	We	-PRON-	PRP
cord-309556-xv3413k1	126	2	showed	show	VBD
cord-309556-xv3413k1	126	3	that	that	IN
cord-309556-xv3413k1	126	4	lung	lung	NN
cord-309556-xv3413k1	126	5	epithelial	epithelial	JJ
cord-309556-xv3413k1	126	6	cells	cell	NNS
cord-309556-xv3413k1	126	7	,	,	,
cord-309556-xv3413k1	126	8	macrophages	macrophage	NNS
cord-309556-xv3413k1	126	9	,	,	,
cord-309556-xv3413k1	126	10	and	and	CC
cord-309556-xv3413k1	126	11	Th1	th1	NN
cord-309556-xv3413k1	126	12	cells	cell	NNS
cord-309556-xv3413k1	126	13	decrease	decrease	VBP
cord-309556-xv3413k1	126	14	in	in	IN
cord-309556-xv3413k1	126	15	abundance	abundance	NN
cord-309556-xv3413k1	126	16	with	with	IN
cord-309556-xv3413k1	126	17	age	age	NN
cord-309556-xv3413k1	126	18	,	,	,
cord-309556-xv3413k1	126	19	whereas	whereas	IN
cord-309556-xv3413k1	126	20	fibroblasts	fibroblast	NNS
cord-309556-xv3413k1	126	21	and	and	CC
cord-309556-xv3413k1	126	22	pericytes	pericyte	NNS
cord-309556-xv3413k1	126	23	increase	increase	VBP
cord-309556-xv3413k1	126	24	in	in	IN
cord-309556-xv3413k1	126	25	abundance	abundance	NN
cord-309556-xv3413k1	126	26	with	with	IN
cord-309556-xv3413k1	126	27	age	age	NN
cord-309556-xv3413k1	126	28	.	.	.
cord-309556-xv3413k1	127	1	These	these	DT
cord-309556-xv3413k1	127	2	systematic	systematic	JJ
cord-309556-xv3413k1	127	3	changes	change	NNS
cord-309556-xv3413k1	127	4	in	in	IN
cord-309556-xv3413k1	127	5	tissue	tissue	NN
cord-309556-xv3413k1	127	6	composition	composition	NN
cord-309556-xv3413k1	127	7	and	and	CC
cord-309556-xv3413k1	127	8	cell	cell	NN
cord-309556-xv3413k1	127	9	interactions	interaction	NNS
cord-309556-xv3413k1	127	10	can	can	MD
cord-309556-xv3413k1	127	11	potentially	potentially	RB
cord-309556-xv3413k1	127	12	propagate	propagate	VB
cord-309556-xv3413k1	127	13	positive	positive	JJ
cord-309556-xv3413k1	127	14	feedback	feedback	NN
cord-309556-xv3413k1	127	15	loops	loop	NNS
cord-309556-xv3413k1	127	16	that	that	WDT
cord-309556-xv3413k1	127	17	predispose	predispose	VBP
cord-309556-xv3413k1	127	18	the	the	DT
cord-309556-xv3413k1	127	19	airways	airway	NNS
cord-309556-xv3413k1	127	20	to	to	IN
cord-309556-xv3413k1	127	21	pathological	pathological	JJ
cord-309556-xv3413k1	127	22	contraction	contraction	NN
cord-309556-xv3413k1	127	23	69	69	CD
cord-309556-xv3413k1	127	24	.	.	.
cord-309556-xv3413k1	128	1	We	-PRON-	PRP
cord-309556-xv3413k1	128	2	find	find	VBP
cord-309556-xv3413k1	128	3	that	that	IN
cord-309556-xv3413k1	128	4	some	some	DT
cord-309556-xv3413k1	128	5	of	of	IN
cord-309556-xv3413k1	128	6	the	the	DT
cord-309556-xv3413k1	128	7	age	age	NN
cord-309556-xv3413k1	128	8	-	-	HYPH
cord-309556-xv3413k1	128	9	associated	associate	VBN
cord-309556-xv3413k1	128	10	genes	gene	NNS
cord-309556-xv3413k1	128	11	have	have	VBP
cord-309556-xv3413k1	128	12	been	be	VBN
cord-309556-xv3413k1	128	13	previously	previously	RB
cord-309556-xv3413k1	128	14	identified	identify	VBN
cord-309556-xv3413k1	128	15	as	as	IN
cord-309556-xv3413k1	128	16	host	host	NN
cord-309556-xv3413k1	128	17	factors	factor	NNS
cord-309556-xv3413k1	128	18	with	with	IN
cord-309556-xv3413k1	128	19	a	a	DT
cord-309556-xv3413k1	128	20	functional	functional	JJ
cord-309556-xv3413k1	128	21	role	role	NN
cord-309556-xv3413k1	128	22	in	in	IN
cord-309556-xv3413k1	128	23	SARS	SARS	NNP
cord-309556-xv3413k1	128	24	-	-	HYPH
cord-309556-xv3413k1	128	25	CoV	CoV	NNP
cord-309556-xv3413k1	128	26	replication	replication	NN
cord-309556-xv3413k1	128	27	63	63	CD
cord-309556-xv3413k1	128	28	,	,	,
cord-309556-xv3413k1	128	29	and	and	CC
cord-309556-xv3413k1	128	30	a	a	DT
cord-309556-xv3413k1	128	31	fraction	fraction	NN
cord-309556-xv3413k1	128	32	of	of	IN
cord-309556-xv3413k1	128	33	the	the	DT
cord-309556-xv3413k1	128	34	age	age	NN
cord-309556-xv3413k1	128	35	-	-	HYPH
cord-309556-xv3413k1	128	36	associated	associate	VBN
cord-309556-xv3413k1	128	37	factors	factor	NNS
cord-309556-xv3413k1	128	38	have	have	VBP
cord-309556-xv3413k1	128	39	been	be	VBN
cord-309556-xv3413k1	128	40	shown	show	VBN
cord-309556-xv3413k1	128	41	to	to	TO
cord-309556-xv3413k1	128	42	directly	directly	RB
cord-309556-xv3413k1	128	43	interact	interact	VB
cord-309556-xv3413k1	128	44	with	with	IN
cord-309556-xv3413k1	128	45	the	the	DT
cord-309556-xv3413k1	128	46	SARS	SARS	NNP
cord-309556-xv3413k1	128	47	-	-	HYPH
cord-309556-xv3413k1	128	48	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	128	49	proteome	proteome	NN
cord-309556-xv3413k1	128	50	64	64	CD
cord-309556-xv3413k1	128	51	.	.	.
cord-309556-xv3413k1	129	1	Furthermore	furthermore	RB
cord-309556-xv3413k1	129	2	,	,	,
cord-309556-xv3413k1	129	3	age	age	NN
cord-309556-xv3413k1	129	4	-	-	HYPH
cord-309556-xv3413k1	129	5	associated	associate	VBN
cord-309556-xv3413k1	129	6	genes	gene	NNS
cord-309556-xv3413k1	129	7	are	be	VBP
cord-309556-xv3413k1	129	8	significantly	significantly	RB
cord-309556-xv3413k1	129	9	enriched	enrich	VBN
cord-309556-xv3413k1	129	10	among	among	IN
cord-309556-xv3413k1	129	11	genes	gene	NNS
cord-309556-xv3413k1	129	12	directly	directly	RB
cord-309556-xv3413k1	129	13	regulated	regulate	VBN
cord-309556-xv3413k1	129	14	by	by	IN
cord-309556-xv3413k1	129	15	SARS	SARS	NNP
cord-309556-xv3413k1	129	16	-	-	HYPH
cord-309556-xv3413k1	129	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	129	18	infection	infection	NN
cord-309556-xv3413k1	129	19	68	68	CD
cord-309556-xv3413k1	129	20	,	,	,
cord-309556-xv3413k1	129	21	suggesting	suggest	VBG
cord-309556-xv3413k1	129	22	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	129	23	parallels	parallel	NNS
cord-309556-xv3413k1	129	24	between	between	IN
cord-309556-xv3413k1	129	25	the	the	DT
cord-309556-xv3413k1	129	26	aging	age	VBG
cord-309556-xv3413k1	129	27	lung	lung	NN
cord-309556-xv3413k1	129	28	and	and	CC
cord-309556-xv3413k1	129	29	SARS	SARS	NNP
cord-309556-xv3413k1	129	30	-	-	HYPH
cord-309556-xv3413k1	129	31	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	129	32	infection	infection	NN
cord-309556-xv3413k1	129	33	.	.	.
cord-309556-xv3413k1	130	1	Moreover	moreover	RB
cord-309556-xv3413k1	130	2	,	,	,
cord-309556-xv3413k1	130	3	it	-PRON-	PRP
cord-309556-xv3413k1	130	4	is	be	VBZ
cord-309556-xv3413k1	130	5	intriguing	intriguing	JJ
cord-309556-xv3413k1	130	6	that	that	IN
cord-309556-xv3413k1	130	7	the	the	DT
cord-309556-xv3413k1	130	8	genes	gene	NNS
cord-309556-xv3413k1	130	9	induced	induce	VBN
cord-309556-xv3413k1	130	10	by	by	IN
cord-309556-xv3413k1	130	11	SARS	SARS	NNP
cord-309556-xv3413k1	130	12	-	-	HYPH
cord-309556-xv3413k1	130	13	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	130	14	infection	infection	NN
cord-309556-xv3413k1	130	15	tend	tend	VBP
cord-309556-xv3413k1	130	16	to	to	TO
cord-309556-xv3413k1	130	17	increase	increase	VB
cord-309556-xv3413k1	130	18	in	in	IN
cord-309556-xv3413k1	130	19	expression	expression	NN
cord-309556-xv3413k1	130	20	with	with	IN
cord-309556-xv3413k1	130	21	aging	age	VBG
cord-309556-xv3413k1	130	22	,	,	,
cord-309556-xv3413k1	130	23	and	and	CC
cord-309556-xv3413k1	130	24	vice	vice	NN
cord-309556-xv3413k1	130	25	versa	versa	RB
cord-309556-xv3413k1	130	26	.	.	.
cord-309556-xv3413k1	131	1	Whether	whether	IN
cord-309556-xv3413k1	131	2	any	any	DT
cord-309556-xv3413k1	131	3	of	of	IN
cord-309556-xv3413k1	131	4	these	these	DT
cord-309556-xv3413k1	131	5	age	age	NN
cord-309556-xv3413k1	131	6	-	-	HYPH
cord-309556-xv3413k1	131	7	associated	associate	VBN
cord-309556-xv3413k1	131	8	changes	change	NNS
cord-309556-xv3413k1	131	9	causally	causally	RB
cord-309556-xv3413k1	131	10	contribute	contribute	VBP
cord-309556-xv3413k1	131	11	to	to	IN
cord-309556-xv3413k1	131	12	the	the	DT
cord-309556-xv3413k1	131	13	heightened	heightened	JJ
cord-309556-xv3413k1	131	14	susceptibility	susceptibility	NN
cord-309556-xv3413k1	131	15	of	of	IN
cord-309556-xv3413k1	131	16	COVID-19	covid-19	DT
cord-309556-xv3413k1	131	17	in	in	IN
cord-309556-xv3413k1	131	18	older	old	JJR
cord-309556-xv3413k1	131	19	populations	population	NNS
cord-309556-xv3413k1	131	20	remains	remain	VBZ
cord-309556-xv3413k1	131	21	to	to	TO
cord-309556-xv3413k1	131	22	be	be	VB
cord-309556-xv3413k1	131	23	experimentally	experimentally	RB
cord-309556-xv3413k1	131	24	tested	test	VBN
cord-309556-xv3413k1	131	25	.	.	.
cord-309556-xv3413k1	132	1	It	-PRON-	PRP
cord-309556-xv3413k1	132	2	is	be	VBZ
cord-309556-xv3413k1	132	3	also	also	RB
cord-309556-xv3413k1	132	4	important	important	JJ
cord-309556-xv3413k1	132	5	to	to	TO
cord-309556-xv3413k1	132	6	note	note	VB
cord-309556-xv3413k1	132	7	that	that	IN
cord-309556-xv3413k1	132	8	the	the	DT
cord-309556-xv3413k1	132	9	datasets	dataset	NNS
cord-309556-xv3413k1	132	10	analyzed	analyze	VBN
cord-309556-xv3413k1	132	11	here	here	RB
cord-309556-xv3413k1	132	12	were	be	VBD
cord-309556-xv3413k1	132	13	not	not	RB
cord-309556-xv3413k1	132	14	from	from	IN
cord-309556-xv3413k1	132	15	patients	patient	NNS
cord-309556-xv3413k1	132	16	with	with	IN
cord-309556-xv3413k1	132	17	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	132	18	.	.	.
cord-309556-xv3413k1	133	1	Given	give	VBN
cord-309556-xv3413k1	133	2	the	the	DT
cord-309556-xv3413k1	133	3	limited	limited	JJ
cord-309556-xv3413k1	133	4	data	datum	NNS
cord-309556-xv3413k1	133	5	that	that	WDT
cord-309556-xv3413k1	133	6	is	be	VBZ
cord-309556-xv3413k1	133	7	currently	currently	RB
cord-309556-xv3413k1	133	8	publicly	publicly	RB
cord-309556-xv3413k1	133	9	available	available	JJ
cord-309556-xv3413k1	133	10	,	,	,
cord-309556-xv3413k1	133	11	we	-PRON-	PRP
cord-309556-xv3413k1	133	12	emphasize	emphasize	VBP
cord-309556-xv3413k1	133	13	that	that	IN
cord-309556-xv3413k1	133	14	the	the	DT
cord-309556-xv3413k1	133	15	analyses	analysis	NNS
cord-309556-xv3413k1	133	16	presented	present	VBN
cord-309556-xv3413k1	133	17	here	here	RB
cord-309556-xv3413k1	133	18	at	at	IN
cord-309556-xv3413k1	133	19	this	this	DT
cord-309556-xv3413k1	133	20	stage	stage	NN
cord-309556-xv3413k1	133	21	should	should	MD
cord-309556-xv3413k1	133	22	not	not	RB
cord-309556-xv3413k1	133	23	be	be	VB
cord-309556-xv3413k1	133	24	used	use	VBN
cord-309556-xv3413k1	133	25	to	to	TO
cord-309556-xv3413k1	133	26	guide	guide	VB
cord-309556-xv3413k1	133	27	clinical	clinical	JJ
cord-309556-xv3413k1	133	28	practice	practice	NN
cord-309556-xv3413k1	133	29	.	.	.
cord-309556-xv3413k1	134	1	These	these	DT
cord-309556-xv3413k1	134	2	analyses	analysis	NNS
cord-309556-xv3413k1	134	3	resulted	result	VBD
cord-309556-xv3413k1	134	4	in	in	IN
cord-309556-xv3413k1	134	5	a	a	DT
cord-309556-xv3413k1	134	6	number	number	NN
cord-309556-xv3413k1	134	7	of	of	IN
cord-309556-xv3413k1	134	8	previously	previously	RB
cord-309556-xv3413k1	134	9	unnoted	unnoted	JJ
cord-309556-xv3413k1	134	10	observations	observation	NNS
cord-309556-xv3413k1	134	11	and	and	CC
cord-309556-xv3413k1	134	12	phenomena	phenomena	JJ
cord-309556-xv3413k1	134	13	that	that	WDT
cord-309556-xv3413k1	134	14	illuminate	illuminate	VBP
cord-309556-xv3413k1	134	15	new	new	JJ
cord-309556-xv3413k1	134	16	directions	direction	NNS
cord-309556-xv3413k1	134	17	for	for	IN
cord-309556-xv3413k1	134	18	subsequent	subsequent	JJ
cord-309556-xv3413k1	134	19	research	research	NN
cord-309556-xv3413k1	134	20	efforts	effort	NNS
cord-309556-xv3413k1	134	21	on	on	IN
cord-309556-xv3413k1	134	22	SARS	SARS	NNP
cord-309556-xv3413k1	134	23	-	-	HYPH
cord-309556-xv3413k1	134	24	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	134	25	,	,	,
cord-309556-xv3413k1	134	26	generating	generate	VBG
cord-309556-xv3413k1	134	27	genetically	genetically	RB
cord-309556-xv3413k1	134	28	-	-	HYPH
cord-309556-xv3413k1	134	29	tractable	tractable	JJ
cord-309556-xv3413k1	134	30	hypotheses	hypothesis	NNS
cord-309556-xv3413k1	134	31	for	for	IN
cord-309556-xv3413k1	134	32	why	why	WRB
cord-309556-xv3413k1	134	33	advanced	advanced	JJ
cord-309556-xv3413k1	134	34	age	age	NN
cord-309556-xv3413k1	134	35	is	be	VBZ
cord-309556-xv3413k1	134	36	one	one	CD
cord-309556-xv3413k1	134	37	of	of	IN
cord-309556-xv3413k1	134	38	the	the	DT
cord-309556-xv3413k1	134	39	strongest	strong	JJS
cord-309556-xv3413k1	134	40	risk	risk	NN
cord-309556-xv3413k1	134	41	factors	factor	NNS
cord-309556-xv3413k1	134	42	for	for	IN
cord-309556-xv3413k1	134	43	COVID-19	covid-19	JJ
cord-309556-xv3413k1	134	44	morbidity	morbidity	NN
cord-309556-xv3413k1	134	45	and	and	CC
cord-309556-xv3413k1	134	46	mortality	mortality	NN
cord-309556-xv3413k1	134	47	.	.	.
cord-309556-xv3413k1	135	1	Ultimately	ultimately	RB
cord-309556-xv3413k1	135	2	,	,	,
cord-309556-xv3413k1	135	3	we	-PRON-	PRP
cord-309556-xv3413k1	135	4	hope	hope	VBP
cord-309556-xv3413k1	135	5	such	such	JJ
cord-309556-xv3413k1	135	6	knowledge	knowledge	NN
cord-309556-xv3413k1	135	7	can	can	MD
cord-309556-xv3413k1	135	8	help	help	VB
cord-309556-xv3413k1	135	9	the	the	DT
cord-309556-xv3413k1	135	10	field	field	NN
cord-309556-xv3413k1	135	11	to	to	TO
cord-309556-xv3413k1	135	12	sooner	sooner	RB
cord-309556-xv3413k1	135	13	develop	develop	VB
cord-309556-xv3413k1	135	14	rational	rational	JJ
cord-309556-xv3413k1	135	15	therapies	therapy	NNS
cord-309556-xv3413k1	135	16	for	for	IN
cord-309556-xv3413k1	135	17	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	135	18	that	that	WDT
cord-309556-xv3413k1	135	19	are	be	VBP
cord-309556-xv3413k1	135	20	rooted	root	VBN
cord-309556-xv3413k1	135	21	in	in	IN
cord-309556-xv3413k1	135	22	concrete	concrete	JJ
cord-309556-xv3413k1	135	23	biological	biological	JJ
cord-309556-xv3413k1	135	24	mechanisms	mechanism	NNS
cord-309556-xv3413k1	135	25	.	.	.
cord-309556-xv3413k1	136	1	We	-PRON-	PRP
cord-309556-xv3413k1	136	2	thank	thank	VBP
cord-309556-xv3413k1	136	3	Akiko	Akiko	NNP
cord-309556-xv3413k1	136	4	Iwasaki	Iwasaki	NNP
cord-309556-xv3413k1	136	5	,	,	,
cord-309556-xv3413k1	136	6	Craig	Craig	NNP
cord-309556-xv3413k1	136	7	Wilen	Wilen	NNP
cord-309556-xv3413k1	136	8	,	,	,
cord-309556-xv3413k1	136	9	Hongyu	Hongyu	NNP
cord-309556-xv3413k1	136	10	Zhao	Zhao	NNP
cord-309556-xv3413k1	136	11	,	,	,
cord-309556-xv3413k1	136	12	Wei	Wei	NNP
cord-309556-xv3413k1	136	13	Liu	Liu	NNP
cord-309556-xv3413k1	136	14	,	,	,
cord-309556-xv3413k1	136	15	Wenxuan	Wenxuan	NNP
cord-309556-xv3413k1	136	16	Deng	Deng	NNP
cord-309556-xv3413k1	136	17	,	,	,
cord-309556-xv3413k1	136	18	Andre	Andre	NNP
cord-309556-xv3413k1	136	19	Levchenko	Levchenko	NNP
cord-309556-xv3413k1	136	20	,	,	,
cord-309556-xv3413k1	136	21	Katie	Katie	NNP
cord-309556-xv3413k1	136	22	Zhu	Zhu	NNP
cord-309556-xv3413k1	136	23	,	,	,
cord-309556-xv3413k1	136	24	Ruth	Ruth	NNP
cord-309556-xv3413k1	136	25	Montgomery	Montgomery	NNP
cord-309556-xv3413k1	136	26	,	,	,
cord-309556-xv3413k1	136	27	Bram	Bram	NNP
cord-309556-xv3413k1	136	28	Gerriten	Gerriten	NNP
cord-309556-xv3413k1	136	29	,	,	,
cord-309556-xv3413k1	136	30	Steven	Steven	NNP
cord-309556-xv3413k1	136	31	Kleinstein	Kleinstein	NNP
cord-309556-xv3413k1	136	32	and	and	CC
cord-309556-xv3413k1	136	33	a	a	DT
cord-309556-xv3413k1	136	34	number	number	NN
cord-309556-xv3413k1	136	35	of	of	IN
cord-309556-xv3413k1	136	36	other	other	JJ
cord-309556-xv3413k1	136	37	colleagues	colleague	NNS
cord-309556-xv3413k1	136	38	for	for	IN
cord-309556-xv3413k1	136	39	their	-PRON-	PRP$
cord-309556-xv3413k1	136	40	critical	critical	JJ
cord-309556-xv3413k1	136	41	comments	comment	NNS
cord-309556-xv3413k1	136	42	and	and	CC
cord-309556-xv3413k1	136	43	suggestions	suggestion	NNS
cord-309556-xv3413k1	136	44	,	,	,
cord-309556-xv3413k1	136	45	which	which	WDT
cord-309556-xv3413k1	136	46	were	be	VBD
cord-309556-xv3413k1	136	47	incorporated	incorporate	VBN
cord-309556-xv3413k1	136	48	into	into	IN
cord-309556-xv3413k1	136	49	the	the	DT
cord-309556-xv3413k1	136	50	analyses	analysis	NNS
cord-309556-xv3413k1	136	51	and	and	CC
cord-309556-xv3413k1	136	52	manuscript	manuscript	NN
cord-309556-xv3413k1	136	53	.	.	.
cord-309556-xv3413k1	137	1	We	-PRON-	PRP
cord-309556-xv3413k1	137	2	thank	thank	VBP
cord-309556-xv3413k1	137	3	Antonio	Antonio	NNP
cord-309556-xv3413k1	137	4	Giraldez	Giraldez	NNP
cord-309556-xv3413k1	137	5	,	,	,
cord-309556-xv3413k1	137	6	Andre	Andre	NNP
cord-309556-xv3413k1	137	7	Levchenko	Levchenko	NNP
cord-309556-xv3413k1	137	8	,	,	,
cord-309556-xv3413k1	137	9	Chris	Chris	NNP
cord-309556-xv3413k1	137	10	Incarvito	Incarvito	NNP
cord-309556-xv3413k1	137	11	,	,	,
cord-309556-xv3413k1	137	12	Mike	Mike	NNP
cord-309556-xv3413k1	137	13	Crair	Crair	NNP
cord-309556-xv3413k1	137	14	,	,	,
cord-309556-xv3413k1	137	15	and	and	CC
cord-309556-xv3413k1	137	16	Scott	Scott	NNP
cord-309556-xv3413k1	137	17	Strobel	Strobel	NNP
cord-309556-xv3413k1	137	18	for	for	IN
cord-309556-xv3413k1	137	19	their	-PRON-	PRP$
cord-309556-xv3413k1	137	20	support	support	NN
cord-309556-xv3413k1	137	21	on	on	IN
cord-309556-xv3413k1	137	22	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	137	23	research	research	NN
cord-309556-xv3413k1	137	24	.	.	.
cord-309556-xv3413k1	138	1	We	-PRON-	PRP
cord-309556-xv3413k1	138	2	thank	thank	VBP
cord-309556-xv3413k1	138	3	our	-PRON-	PRP$
cord-309556-xv3413k1	138	4	colleagues	colleague	NNS
cord-309556-xv3413k1	138	5	in	in	IN
cord-309556-xv3413k1	138	6	the	the	DT
cord-309556-xv3413k1	138	7	Chen	Chen	NNP
cord-309556-xv3413k1	138	8	lab	lab	NN
cord-309556-xv3413k1	138	9	,	,	,
cord-309556-xv3413k1	138	10	the	the	DT
cord-309556-xv3413k1	138	11	Genetics	Genetics	NNP
cord-309556-xv3413k1	138	12	Department	Department	NNP
cord-309556-xv3413k1	138	13	,	,	,
cord-309556-xv3413k1	138	14	the	the	DT
cord-309556-xv3413k1	138	15	Systems	Systems	NNPS
cord-309556-xv3413k1	138	16	Biology	Biology	NNP
cord-309556-xv3413k1	138	17	Institute	Institute	NNP
cord-309556-xv3413k1	138	18	and	and	CC
cord-309556-xv3413k1	138	19	various	various	JJ
cord-309556-xv3413k1	138	20	Yale	Yale	NNP
cord-309556-xv3413k1	138	21	entities	entity	NNS
cord-309556-xv3413k1	138	22	.	.	.
cord-309556-xv3413k1	139	1	We	-PRON-	PRP
cord-309556-xv3413k1	139	2	also	also	RB
cord-309556-xv3413k1	139	3	want	want	VBP
cord-309556-xv3413k1	139	4	to	to	TO
cord-309556-xv3413k1	139	5	thank	thank	VB
cord-309556-xv3413k1	139	6	all	all	DT
cord-309556-xv3413k1	139	7	of	of	IN
cord-309556-xv3413k1	139	8	the	the	DT
cord-309556-xv3413k1	139	9	healthcare	healthcare	NN
cord-309556-xv3413k1	139	10	workers	worker	NNS
cord-309556-xv3413k1	139	11	who	who	WP
cord-309556-xv3413k1	139	12	are	be	VBP
cord-309556-xv3413k1	139	13	risking	risk	VBG
cord-309556-xv3413k1	139	14	their	-PRON-	PRP$
cord-309556-xv3413k1	139	15	health	health	NN
cord-309556-xv3413k1	139	16	on	on	IN
cord-309556-xv3413k1	139	17	the	the	DT
cord-309556-xv3413k1	139	18	frontlines	frontline	NNS
cord-309556-xv3413k1	139	19	to	to	TO
cord-309556-xv3413k1	139	20	treat	treat	VB
cord-309556-xv3413k1	139	21	patients	patient	NNS
cord-309556-xv3413k1	139	22	with	with	IN
cord-309556-xv3413k1	139	23	this	this	DT
cord-309556-xv3413k1	139	24	disease	disease	NN
cord-309556-xv3413k1	139	25	.	.	.
cord-309556-xv3413k1	140	1	RC	RC	NNP
cord-309556-xv3413k1	140	2	and	and	CC
cord-309556-xv3413k1	140	3	SC	SC	NNP
cord-309556-xv3413k1	140	4	conceived	conceive	VBD
cord-309556-xv3413k1	140	5	and	and	CC
cord-309556-xv3413k1	140	6	designed	design	VBD
cord-309556-xv3413k1	140	7	the	the	DT
cord-309556-xv3413k1	140	8	study	study	NN
cord-309556-xv3413k1	140	9	.	.	.
cord-309556-xv3413k1	141	1	RC	RC	NNP
cord-309556-xv3413k1	141	2	developed	develop	VBD
cord-309556-xv3413k1	141	3	the	the	DT
cord-309556-xv3413k1	141	4	analysis	analysis	NN
cord-309556-xv3413k1	141	5	approach	approach	NN
cord-309556-xv3413k1	141	6	,	,	,
cord-309556-xv3413k1	141	7	performed	perform	VBD
cord-309556-xv3413k1	141	8	all	all	DT
cord-309556-xv3413k1	141	9	data	data	NN
cord-309556-xv3413k1	141	10	analyses	analysis	NNS
cord-309556-xv3413k1	141	11	,	,	,
cord-309556-xv3413k1	141	12	and	and	CC
cord-309556-xv3413k1	141	13	created	create	VBD
cord-309556-xv3413k1	141	14	the	the	DT
cord-309556-xv3413k1	141	15	figures	figure	NNS
cord-309556-xv3413k1	141	16	.	.	.
cord-309556-xv3413k1	142	1	RC	RC	NNP
cord-309556-xv3413k1	142	2	and	and	CC
cord-309556-xv3413k1	142	3	SC	SC	NNP
cord-309556-xv3413k1	142	4	prepared	prepare	VBD
cord-309556-xv3413k1	142	5	the	the	DT
cord-309556-xv3413k1	142	6	manuscript	manuscript	NN
cord-309556-xv3413k1	142	7	.	.	.
cord-309556-xv3413k1	143	1	SC	SC	NNP
cord-309556-xv3413k1	143	2	supervised	supervise	VBD
cord-309556-xv3413k1	143	3	the	the	DT
cord-309556-xv3413k1	143	4	work	work	NN
cord-309556-xv3413k1	143	5	.	.	.
cord-309556-xv3413k1	144	1	No	no	DT
cord-309556-xv3413k1	144	2	competing	compete	VBG
cord-309556-xv3413k1	144	3	interests	interest	NNS
cord-309556-xv3413k1	144	4	related	relate	VBN
cord-309556-xv3413k1	144	5	to	to	IN
cord-309556-xv3413k1	144	6	this	this	DT
cord-309556-xv3413k1	144	7	study	study	NN
cord-309556-xv3413k1	144	8	.	.	.
cord-309556-xv3413k1	145	1	The	the	DT
cord-309556-xv3413k1	145	2	authors	author	NNS
cord-309556-xv3413k1	145	3	have	have	VBP
cord-309556-xv3413k1	145	4	no	no	DT
cord-309556-xv3413k1	145	5	competing	compete	VBG
cord-309556-xv3413k1	145	6	interests	interest	NNS
cord-309556-xv3413k1	145	7	as	as	IN
cord-309556-xv3413k1	145	8	defined	define	VBN
cord-309556-xv3413k1	145	9	by	by	IN
cord-309556-xv3413k1	145	10	Nature	Nature	NNP
cord-309556-xv3413k1	145	11	Research	Research	NNP
cord-309556-xv3413k1	145	12	,	,	,
cord-309556-xv3413k1	145	13	or	or	CC
cord-309556-xv3413k1	145	14	other	other	JJ
cord-309556-xv3413k1	145	15	interests	interest	NNS
cord-309556-xv3413k1	145	16	that	that	WDT
cord-309556-xv3413k1	145	17	might	may	MD
cord-309556-xv3413k1	145	18	be	be	VB
cord-309556-xv3413k1	145	19	perceived	perceive	VBN
cord-309556-xv3413k1	145	20	to	to	TO
cord-309556-xv3413k1	145	21	influence	influence	VB
cord-309556-xv3413k1	145	22	the	the	DT
cord-309556-xv3413k1	145	23	interpretation	interpretation	NN
cord-309556-xv3413k1	145	24	of	of	IN
cord-309556-xv3413k1	145	25	the	the	DT
cord-309556-xv3413k1	145	26	article	article	NN
cord-309556-xv3413k1	145	27	.	.	.
cord-309556-xv3413k1	146	1	The	the	DT
cord-309556-xv3413k1	146	2	authors	author	NNS
cord-309556-xv3413k1	146	3	are	be	VBP
cord-309556-xv3413k1	146	4	committed	commit	VBN
cord-309556-xv3413k1	146	5	to	to	TO
cord-309556-xv3413k1	146	6	freely	freely	RB
cord-309556-xv3413k1	146	7	share	share	VB
cord-309556-xv3413k1	146	8	all	all	DT
cord-309556-xv3413k1	146	9	COVID-19	covid-19	JJ
cord-309556-xv3413k1	146	10	related	related	JJ
cord-309556-xv3413k1	146	11	data	datum	NNS
cord-309556-xv3413k1	146	12	,	,	,
cord-309556-xv3413k1	146	13	knowledge	knowledge	NN
cord-309556-xv3413k1	146	14	and	and	CC
cord-309556-xv3413k1	146	15	resources	resource	NNS
cord-309556-xv3413k1	146	16	to	to	IN
cord-309556-xv3413k1	146	17	the	the	DT
cord-309556-xv3413k1	146	18	community	community	NN
cord-309556-xv3413k1	146	19	to	to	TO
cord-309556-xv3413k1	146	20	facilitate	facilitate	VB
cord-309556-xv3413k1	146	21	the	the	DT
cord-309556-xv3413k1	146	22	development	development	NN
cord-309556-xv3413k1	146	23	of	of	IN
cord-309556-xv3413k1	146	24	new	new	JJ
cord-309556-xv3413k1	146	25	treatment	treatment	NN
cord-309556-xv3413k1	146	26	or	or	CC
cord-309556-xv3413k1	146	27	prevention	prevention	NN
cord-309556-xv3413k1	146	28	approaches	approach	NNS
cord-309556-xv3413k1	146	29	against	against	IN
cord-309556-xv3413k1	146	30	SARS	SARS	NNP
cord-309556-xv3413k1	146	31	-	-	HYPH
cord-309556-xv3413k1	146	32	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	146	33	/	/	.
cord-309556-xv3413k1	147	1	COVID-19	covid-19	VB
cord-309556-xv3413k1	147	2	as	as	RB
cord-309556-xv3413k1	147	3	soon	soon	RB
cord-309556-xv3413k1	147	4	as	as	IN
cord-309556-xv3413k1	147	5	possible	possible	JJ
cord-309556-xv3413k1	147	6	.	.	.
cord-309556-xv3413k1	148	1	As	as	IN
cord-309556-xv3413k1	148	2	a	a	DT
cord-309556-xv3413k1	148	3	note	note	NN
cord-309556-xv3413k1	148	4	for	for	IN
cord-309556-xv3413k1	148	5	full	full	JJ
cord-309556-xv3413k1	148	6	disclosure	disclosure	NN
cord-309556-xv3413k1	148	7	,	,	,
cord-309556-xv3413k1	148	8	SC	SC	NNP
cord-309556-xv3413k1	148	9	is	be	VBZ
cord-309556-xv3413k1	148	10	a	a	DT
cord-309556-xv3413k1	148	11	co	co	NN
cord-309556-xv3413k1	148	12	-	-	NN
cord-309556-xv3413k1	148	13	founder	founder	NN
cord-309556-xv3413k1	148	14	,	,	,
cord-309556-xv3413k1	148	15	funding	funding	NN
cord-309556-xv3413k1	148	16	recipient	recipient	NN
cord-309556-xv3413k1	148	17	and	and	CC
cord-309556-xv3413k1	148	18	scientific	scientific	JJ
cord-309556-xv3413k1	148	19	advisor	advisor	NN
cord-309556-xv3413k1	148	20	of	of	IN
cord-309556-xv3413k1	148	21	EvolveImmune	EvolveImmune	NNP
cord-309556-xv3413k1	148	22	Therapeutics	Therapeutics	NNP
cord-309556-xv3413k1	148	23	,	,	,
cord-309556-xv3413k1	148	24	which	which	WDT
cord-309556-xv3413k1	148	25	is	be	VBZ
cord-309556-xv3413k1	148	26	not	not	RB
cord-309556-xv3413k1	148	27	related	relate	VBN
cord-309556-xv3413k1	148	28	to	to	IN
cord-309556-xv3413k1	148	29	this	this	DT
cord-309556-xv3413k1	148	30	study	study	NN
cord-309556-xv3413k1	148	31	.	.	.
cord-309556-xv3413k1	149	1	c.	c.	NNP
cord-309556-xv3413k1	149	2	DAVID	DAVID	NNP
cord-309556-xv3413k1	149	3	gene	gene	NN
cord-309556-xv3413k1	149	4	ontology	ontology	NN
cord-309556-xv3413k1	149	5	and	and	CC
cord-309556-xv3413k1	149	6	pathway	pathway	NN
cord-309556-xv3413k1	149	7	analysis	analysis	NN
cord-309556-xv3413k1	149	8	of	of	IN
cord-309556-xv3413k1	149	9	Cluster	cluster	NN
cord-309556-xv3413k1	149	10	1	1	CD
cord-309556-xv3413k1	149	11	age	age	NN
cord-309556-xv3413k1	149	12	-	-	HYPH
cord-309556-xv3413k1	149	13	associated	associate	VBN
cord-309556-xv3413k1	149	14	genes	gene	NNS
cord-309556-xv3413k1	149	15	that	that	WDT
cord-309556-xv3413k1	149	16	exhibit	exhibit	VBP
cord-309556-xv3413k1	149	17	enriched	enrich	VBN
cord-309556-xv3413k1	149	18	expression	expression	NN
cord-309556-xv3413k1	149	19	in	in	IN
cord-309556-xv3413k1	149	20	muscle	muscle	NN
cord-309556-xv3413k1	149	21	cells	cell	NNS
cord-309556-xv3413k1	149	22	.	.	.
cord-309556-xv3413k1	150	1	d.	d.	NNP
cord-309556-xv3413k1	150	2	DAVID	DAVID	NNP
cord-309556-xv3413k1	150	3	gene	gene	NN
cord-309556-xv3413k1	150	4	ontology	ontology	NN
cord-309556-xv3413k1	150	5	and	and	CC
cord-309556-xv3413k1	150	6	pathway	pathway	NN
cord-309556-xv3413k1	150	7	analysis	analysis	NN
cord-309556-xv3413k1	150	8	of	of	IN
cord-309556-xv3413k1	150	9	Cluster	cluster	NN
cord-309556-xv3413k1	150	10	2	2	CD
cord-309556-xv3413k1	150	11	age	age	NN
cord-309556-xv3413k1	150	12	-	-	HYPH
cord-309556-xv3413k1	150	13	associated	associate	VBN
cord-309556-xv3413k1	150	14	genes	gene	NNS
cord-309556-xv3413k1	150	15	that	that	WDT
cord-309556-xv3413k1	150	16	exhibit	exhibit	VBP
cord-309556-xv3413k1	150	17	enriched	enrich	VBN
cord-309556-xv3413k1	150	18	expression	expression	NN
cord-309556-xv3413k1	150	19	in	in	IN
cord-309556-xv3413k1	150	20	alveolar	alveolar	JJ
cord-309556-xv3413k1	150	21	type	type	NN
cord-309556-xv3413k1	150	22	2	2	CD
cord-309556-xv3413k1	150	23	(	(	-LRB-
cord-309556-xv3413k1	150	24	AT2	at2	NN
cord-309556-xv3413k1	150	25	)	)	-RRB-
cord-309556-xv3413k1	150	26	cells	cell	NNS
cord-309556-xv3413k1	150	27	.	.	.
cord-309556-xv3413k1	151	1	a.	a.	NN
cord-309556-xv3413k1	152	1	Venn	Venn	NNP
cord-309556-xv3413k1	152	2	diagram	diagram	NN
cord-309556-xv3413k1	152	3	of	of	IN
cord-309556-xv3413k1	152	4	the	the	DT
cord-309556-xv3413k1	152	5	intersection	intersection	NN
cord-309556-xv3413k1	152	6	between	between	IN
cord-309556-xv3413k1	152	7	age	age	NN
cord-309556-xv3413k1	152	8	-	-	HYPH
cord-309556-xv3413k1	152	9	associated	associate	VBN
cord-309556-xv3413k1	152	10	genes	gene	NNS
cord-309556-xv3413k1	152	11	in	in	IN
cord-309556-xv3413k1	152	12	human	human	JJ
cord-309556-xv3413k1	152	13	lung	lung	NN
cord-309556-xv3413k1	152	14	and	and	CC
cord-309556-xv3413k1	152	15	the	the	DT
cord-309556-xv3413k1	152	16	SARS	SARS	NNP
cord-309556-xv3413k1	152	17	-	-	HYPH
cord-309556-xv3413k1	152	18	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	152	19	:	:	:
cord-309556-xv3413k1	152	20	Human	human	JJ
cord-309556-xv3413k1	152	21	protein	protein	NN
cord-309556-xv3413k1	152	22	interactome	interactome	NNP
cord-309556-xv3413k1	153	1	(	(	-LRB-
cord-309556-xv3413k1	153	2	Gordon	Gordon	NNP
cord-309556-xv3413k1	153	3	et	et	NNP
cord-309556-xv3413k1	153	4	al	al	NNP
cord-309556-xv3413k1	153	5	.	.	NNP
cord-309556-xv3413k1	153	6	,	,	,
cord-309556-xv3413k1	153	7	2020	2020	CD
cord-309556-xv3413k1	153	8	)	)	-RRB-
cord-309556-xv3413k1	153	9	.	.	.
cord-309556-xv3413k1	154	1	Of	of	IN
cord-309556-xv3413k1	154	2	the	the	DT
cord-309556-xv3413k1	154	3	20	20	CD
cord-309556-xv3413k1	154	4	age	age	NN
cord-309556-xv3413k1	154	5	-	-	HYPH
cord-309556-xv3413k1	154	6	associated	associate	VBN
cord-309556-xv3413k1	154	7	genes	gene	NNS
cord-309556-xv3413k1	154	8	that	that	WDT
cord-309556-xv3413k1	154	9	were	be	VBD
cord-309556-xv3413k1	154	10	found	find	VBN
cord-309556-xv3413k1	154	11	to	to	TO
cord-309556-xv3413k1	154	12	also	also	RB
cord-309556-xv3413k1	154	13	interact	interact	VB
cord-309556-xv3413k1	154	14	with	with	IN
cord-309556-xv3413k1	154	15	SARS	SARS	NNP
cord-309556-xv3413k1	154	16	-	-	HYPH
cord-309556-xv3413k1	154	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	154	18	,	,	,
cord-309556-xv3413k1	154	19	4	4	CD
cord-309556-xv3413k1	154	20	of	of	IN
cord-309556-xv3413k1	154	21	them	-PRON-	PRP
cord-309556-xv3413k1	154	22	increased	increase	VBD
cord-309556-xv3413k1	154	23	in	in	IN
cord-309556-xv3413k1	154	24	expression	expression	NN
cord-309556-xv3413k1	154	25	with	with	IN
cord-309556-xv3413k1	154	26	age	age	NN
cord-309556-xv3413k1	154	27	,	,	,
cord-309556-xv3413k1	154	28	while	while	IN
cord-309556-xv3413k1	154	29	16	16	CD
cord-309556-xv3413k1	154	30	decreased	decrease	VBD
cord-309556-xv3413k1	154	31	with	with	IN
cord-309556-xv3413k1	154	32	age	age	NN
cord-309556-xv3413k1	154	33	.	.	.
cord-309556-xv3413k1	155	1	b.	b.	NNP
cord-309556-xv3413k1	155	2	Age	Age	NNP
cord-309556-xv3413k1	155	3	-	-	HYPH
cord-309556-xv3413k1	155	4	associated	associate	VBN
cord-309556-xv3413k1	155	5	genes	gene	NNS
cord-309556-xv3413k1	155	6	in	in	IN
cord-309556-xv3413k1	155	7	human	human	JJ
cord-309556-xv3413k1	155	8	lung	lung	NN
cord-309556-xv3413k1	155	9	and	and	CC
cord-309556-xv3413k1	155	10	their	-PRON-	PRP$
cord-309556-xv3413k1	155	11	interaction	interaction	NN
cord-309556-xv3413k1	155	12	with	with	IN
cord-309556-xv3413k1	155	13	SARS	SARS	NNP
cord-309556-xv3413k1	155	14	-	-	HYPH
cord-309556-xv3413k1	155	15	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	155	16	proteins	protein	NNS
cord-309556-xv3413k1	155	17	,	,	,
cord-309556-xv3413k1	155	18	where	where	WRB
cord-309556-xv3413k1	155	19	each	each	DT
cord-309556-xv3413k1	155	20	block	block	NN
cord-309556-xv3413k1	155	21	contains	contain	VBZ
cord-309556-xv3413k1	155	22	a	a	DT
cord-309556-xv3413k1	155	23	SARS	SARS	NNP
cord-309556-xv3413k1	155	24	-	-	HYPH
cord-309556-xv3413k1	155	25	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	155	26	protein	protein	NN
cord-309556-xv3413k1	155	27	(	(	-LRB-
cord-309556-xv3413k1	155	28	underlined	underline	VBN
cord-309556-xv3413k1	155	29	)	)	-RRB-
cord-309556-xv3413k1	155	30	and	and	CC
cord-309556-xv3413k1	155	31	its	-PRON-	PRP$
cord-309556-xv3413k1	155	32	interacting	interact	VBG
cord-309556-xv3413k1	155	33	age	age	NN
cord-309556-xv3413k1	155	34	-	-	HYPH
cord-309556-xv3413k1	155	35	associated	associate	VBN
cord-309556-xv3413k1	155	36	factors	factor	NNS
cord-309556-xv3413k1	155	37	.	.	.
cord-309556-xv3413k1	156	1	Blocks	block	NNS
cord-309556-xv3413k1	156	2	are	be	VBP
cord-309556-xv3413k1	156	3	colored	color	VBN
cord-309556-xv3413k1	156	4	by	by	IN
cord-309556-xv3413k1	156	5	the	the	DT
cord-309556-xv3413k1	156	6	dominant	dominant	JJ
cord-309556-xv3413k1	156	7	directionality	directionality	NN
cord-309556-xv3413k1	156	8	of	of	IN
cord-309556-xv3413k1	156	9	the	the	DT
cord-309556-xv3413k1	156	10	age	age	NNP
cord-309556-xv3413k1	156	11	association	association	NNP
cord-309556-xv3413k1	156	12	(	(	-LRB-
cord-309556-xv3413k1	156	13	orange	orange	NNP
cord-309556-xv3413k1	156	14	,	,	,
cord-309556-xv3413k1	156	15	decreasing	decrease	VBG
cord-309556-xv3413k1	156	16	with	with	IN
cord-309556-xv3413k1	156	17	age	age	NN
cord-309556-xv3413k1	156	18	;	;	,
cord-309556-xv3413k1	156	19	blue	blue	JJ
cord-309556-xv3413k1	156	20	,	,	,
cord-309556-xv3413k1	156	21	increasing	increase	VBG
cord-309556-xv3413k1	156	22	with	with	IN
cord-309556-xv3413k1	156	23	age	age	NN
cord-309556-xv3413k1	156	24	)	)	-RRB-
cord-309556-xv3413k1	156	25	.	.	.
cord-309556-xv3413k1	157	1	Gene	gene	NN
cord-309556-xv3413k1	157	2	targets	target	NNS
cord-309556-xv3413k1	157	3	with	with	IN
cord-309556-xv3413k1	157	4	already	already	RB
cord-309556-xv3413k1	157	5	approved	approve	VBN
cord-309556-xv3413k1	157	6	drugs	drug	NNS
cord-309556-xv3413k1	157	7	,	,	,
cord-309556-xv3413k1	157	8	investigational	investigational	JJ
cord-309556-xv3413k1	157	9	new	new	JJ
cord-309556-xv3413k1	157	10	drugs	drug	NNS
cord-309556-xv3413k1	157	11	,	,	,
cord-309556-xv3413k1	157	12	or	or	CC
cord-309556-xv3413k1	157	13	preclinical	preclinical	JJ
cord-309556-xv3413k1	157	14	molecules	molecule	NNS
cord-309556-xv3413k1	157	15	are	be	VBP
cord-309556-xv3413k1	157	16	additionally	additionally	RB
cord-309556-xv3413k1	157	17	denoted	denote	VBN
cord-309556-xv3413k1	157	18	with	with	IN
cord-309556-xv3413k1	157	19	an	an	DT
cord-309556-xv3413k1	157	20	asterisk	asterisk	NN
cord-309556-xv3413k1	157	21	.	.	.
cord-309556-xv3413k1	157	22	 	 	_SP
cord-309556-xv3413k1	158	1	The	the	DT
cord-309556-xv3413k1	158	2	Genotype	Genotype	NNP
cord-309556-xv3413k1	158	3	-	-	HYPH
cord-309556-xv3413k1	158	4	Tissue	Tissue	NNP
cord-309556-xv3413k1	158	5	Expression	expression	NN
cord-309556-xv3413k1	158	6	(	(	-LRB-
cord-309556-xv3413k1	158	7	GTEx	gtex	NN
cord-309556-xv3413k1	158	8	)	)	-RRB-
cord-309556-xv3413k1	158	9	Project	Project	NNP
cord-309556-xv3413k1	158	10	was	be	VBD
cord-309556-xv3413k1	158	11	supported	support	VBN
cord-309556-xv3413k1	158	12	by	by	IN
cord-309556-xv3413k1	158	13	the	the	DT
cord-309556-xv3413k1	158	14	Common	Common	NNP
cord-309556-xv3413k1	158	15	Fund	Fund	NNP
cord-309556-xv3413k1	158	16	of	of	IN
cord-309556-xv3413k1	158	17	the	the	DT
cord-309556-xv3413k1	158	18	Office	Office	NNP
cord-309556-xv3413k1	158	19	of	of	IN
cord-309556-xv3413k1	158	20	the	the	DT
cord-309556-xv3413k1	158	21	Director	Director	NNP
cord-309556-xv3413k1	158	22	of	of	IN
cord-309556-xv3413k1	158	23	the	the	DT
cord-309556-xv3413k1	158	24	National	National	NNP
cord-309556-xv3413k1	158	25	Institutes	Institutes	NNPS
cord-309556-xv3413k1	158	26	of	of	IN
cord-309556-xv3413k1	158	27	Health	Health	NNP
cord-309556-xv3413k1	158	28	,	,	,
cord-309556-xv3413k1	158	29	and	and	CC
cord-309556-xv3413k1	158	30	by	by	IN
cord-309556-xv3413k1	158	31	NCI	NCI	NNP
cord-309556-xv3413k1	158	32	,	,	,
cord-309556-xv3413k1	158	33	NHGRI	NHGRI	NNP
cord-309556-xv3413k1	158	34	,	,	,
cord-309556-xv3413k1	158	35	NHLBI	NHLBI	NNP
cord-309556-xv3413k1	158	36	,	,	,
cord-309556-xv3413k1	158	37	NIDA	NIDA	NNP
cord-309556-xv3413k1	158	38	,	,	,
cord-309556-xv3413k1	158	39	NIMH	NIMH	NNP
cord-309556-xv3413k1	158	40	,	,	,
cord-309556-xv3413k1	158	41	and	and	CC
cord-309556-xv3413k1	158	42	NINDS	NINDS	NNP
cord-309556-xv3413k1	158	43	10	10	CD
cord-309556-xv3413k1	158	44	,	,	,
cord-309556-xv3413k1	158	45	11	11	CD
cord-309556-xv3413k1	158	46	.	.	.
cord-309556-xv3413k1	159	1	RNA	RNA	NNP
cord-309556-xv3413k1	159	2	-	-	HYPH
cord-309556-xv3413k1	159	3	seq	seq	NN
cord-309556-xv3413k1	159	4	raw	raw	JJ
cord-309556-xv3413k1	159	5	counts	count	NNS
cord-309556-xv3413k1	159	6	and	and	CC
cord-309556-xv3413k1	159	7	normalized	normalize	VBN
cord-309556-xv3413k1	159	8	TPM	TPM	NNP
cord-309556-xv3413k1	159	9	matrices	matrix	NNS
cord-309556-xv3413k1	159	10	were	be	VBD
cord-309556-xv3413k1	159	11	downloaded	download	VBN
cord-309556-xv3413k1	159	12	from	from	IN
cord-309556-xv3413k1	159	13	the	the	DT
cord-309556-xv3413k1	159	14	GTEx	GTEx	NNP
cord-309556-xv3413k1	159	15	Portal	Portal	NNP
cord-309556-xv3413k1	159	16	(	(	-LRB-
cord-309556-xv3413k1	159	17	https://gtexportal.org/home/index.html	https://gtexportal.org/home/index.html	ADD
cord-309556-xv3413k1	159	18	)	)	-RRB-
cord-309556-xv3413k1	159	19	on	on	IN
cord-309556-xv3413k1	159	20	March	March	NNP
cord-309556-xv3413k1	159	21	18	18	CD
cord-309556-xv3413k1	159	22	,	,	,
cord-309556-xv3413k1	159	23	2020	2020	CD
cord-309556-xv3413k1	159	24	,	,	,
cord-309556-xv3413k1	159	25	release	release	VB
cord-309556-xv3413k1	159	26	v8	v8	NNP
cord-309556-xv3413k1	159	27	.	.	.
cord-309556-xv3413k1	160	1	All	all	DT
cord-309556-xv3413k1	160	2	accessed	access	VBN
cord-309556-xv3413k1	160	3	data	datum	NNS
cord-309556-xv3413k1	160	4	used	use	VBN
cord-309556-xv3413k1	160	5	in	in	IN
cord-309556-xv3413k1	160	6	this	this	DT
cord-309556-xv3413k1	160	7	study	study	NN
cord-309556-xv3413k1	160	8	are	be	VBP
cord-309556-xv3413k1	160	9	publicly	publicly	RB
cord-309556-xv3413k1	160	10	available	available	JJ
cord-309556-xv3413k1	160	11	on	on	IN
cord-309556-xv3413k1	160	12	the	the	DT
cord-309556-xv3413k1	160	13	web	web	NN
cord-309556-xv3413k1	160	14	portal	portal	NN
cord-309556-xv3413k1	160	15	and	and	CC
cord-309556-xv3413k1	160	16	have	have	VBP
cord-309556-xv3413k1	160	17	been	be	VBN
cord-309556-xv3413k1	160	18	deidentified	deidentifie	VBN
cord-309556-xv3413k1	160	19	,	,	,
cord-309556-xv3413k1	160	20	except	except	IN
cord-309556-xv3413k1	160	21	for	for	IN
cord-309556-xv3413k1	160	22	patient	patient	JJ
cord-309556-xv3413k1	160	23	age	age	NN
cord-309556-xv3413k1	160	24	range	range	NN
cord-309556-xv3413k1	160	25	and	and	CC
cord-309556-xv3413k1	160	26	gender	gender	NN
cord-309556-xv3413k1	160	27	.	.	.
cord-309556-xv3413k1	161	1	Case	case	NN
cord-309556-xv3413k1	161	2	-	-	HYPH
cord-309556-xv3413k1	161	3	fatality	fatality	NN
cord-309556-xv3413k1	161	4	rates	rate	NNS
cord-309556-xv3413k1	161	5	in	in	IN
cord-309556-xv3413k1	161	6	China	China	NNP
cord-309556-xv3413k1	161	7	and	and	CC
cord-309556-xv3413k1	161	8	Italy	Italy	NNP
cord-309556-xv3413k1	161	9	were	be	VBD
cord-309556-xv3413k1	161	10	from	from	IN
cord-309556-xv3413k1	161	11	the	the	DT
cord-309556-xv3413k1	161	12	Chinese	chinese	JJ
cord-309556-xv3413k1	161	13	CDC	CDC	NNP
cord-309556-xv3413k1	161	14	and	and	CC
cord-309556-xv3413k1	161	15	Italian	italian	JJ
cord-309556-xv3413k1	161	16	ISS	ISS	NNP
cord-309556-xv3413k1	161	17	,	,	,
cord-309556-xv3413k1	161	18	 	 	_SP
cord-309556-xv3413k1	161	19	For	for	IN
cord-309556-xv3413k1	161	20	visualization	visualization	NN
cord-309556-xv3413k1	161	21	of	of	IN
cord-309556-xv3413k1	161	22	RNA	RNA	NNP
cord-309556-xv3413k1	161	23	-	-	HYPH
cord-309556-xv3413k1	161	24	seq	seq	NNP
cord-309556-xv3413k1	161	25	expression	expression	NN
cord-309556-xv3413k1	161	26	data	datum	NNS
cord-309556-xv3413k1	161	27	,	,	,
cord-309556-xv3413k1	161	28	the	the	DT
cord-309556-xv3413k1	161	29	TPM	TPM	NNP
cord-309556-xv3413k1	161	30	values	value	NNS
cord-309556-xv3413k1	161	31	were	be	VBD
cord-309556-xv3413k1	161	32	log2	log2	NNS
cord-309556-xv3413k1	161	33	transformed	transform	VBN
cord-309556-xv3413k1	161	34	and	and	CC
cord-309556-xv3413k1	161	35	plotted	plot	VBN
cord-309556-xv3413k1	161	36	in	in	IN
cord-309556-xv3413k1	161	37	R	r	NN
cord-309556-xv3413k1	161	38	(	(	-LRB-
cord-309556-xv3413k1	161	39	v3.6.1	v3.6.1	NNP
cord-309556-xv3413k1	161	40	)	)	-RRB-
cord-309556-xv3413k1	161	41	.	.	.
cord-309556-xv3413k1	162	1	All	all	DT
cord-309556-xv3413k1	162	2	boxplots	boxplot	NNS
cord-309556-xv3413k1	162	3	are	be	VBP
cord-309556-xv3413k1	162	4	Tukey	Tukey	NNP
cord-309556-xv3413k1	162	5	boxplots	boxplot	NNS
cord-309556-xv3413k1	162	6	,	,	,
cord-309556-xv3413k1	162	7	with	with	IN
cord-309556-xv3413k1	162	8	interquartile	interquartile	JJ
cord-309556-xv3413k1	162	9	range	range	NN
cord-309556-xv3413k1	162	10	(	(	-LRB-
cord-309556-xv3413k1	162	11	IQR	IQR	NNP
cord-309556-xv3413k1	162	12	)	)	-RRB-
cord-309556-xv3413k1	162	13	boxes	box	NNS
cord-309556-xv3413k1	162	14	and	and	CC
cord-309556-xv3413k1	162	15	1.5	1.5	CD
cord-309556-xv3413k1	162	16	×	×	NN
cord-309556-xv3413k1	162	17	IQR	IQR	NNP
cord-309556-xv3413k1	162	18	whiskers	whisker	NNS
cord-309556-xv3413k1	162	19	.	.	.
cord-309556-xv3413k1	163	1	Pairwise	pairwise	JJ
cord-309556-xv3413k1	163	2	statistical	statistical	JJ
cord-309556-xv3413k1	163	3	comparisons	comparison	NNS
cord-309556-xv3413k1	163	4	in	in	IN
cord-309556-xv3413k1	163	5	the	the	DT
cord-309556-xv3413k1	163	6	plots	plot	NNS
cord-309556-xv3413k1	163	7	were	be	VBD
cord-309556-xv3413k1	163	8	assessed	assess	VBN
cord-309556-xv3413k1	163	9	by	by	IN
cord-309556-xv3413k1	163	10	two	two	CD
cord-309556-xv3413k1	163	11	-	-	HYPH
cord-309556-xv3413k1	163	12	tailed	tailed	JJ
cord-309556-xv3413k1	163	13	Mann	Mann	NNP
cord-309556-xv3413k1	163	14	-	-	HYPH
cord-309556-xv3413k1	163	15	Whitney	Whitney	NNP
cord-309556-xv3413k1	163	16	test	test	NN
cord-309556-xv3413k1	163	17	,	,	,
cord-309556-xv3413k1	163	18	while	while	IN
cord-309556-xv3413k1	163	19	statistical	statistical	JJ
cord-309556-xv3413k1	163	20	comparisons	comparison	NNS
cord-309556-xv3413k1	163	21	across	across	IN
cord-309556-xv3413k1	163	22	all	all	DT
cord-309556-xv3413k1	163	23	age	age	NN
cord-309556-xv3413k1	163	24	groups	group	NNS
cord-309556-xv3413k1	163	25	were	be	VBD
cord-309556-xv3413k1	163	26	performed	perform	VBN
cord-309556-xv3413k1	163	27	by	by	IN
cord-309556-xv3413k1	163	28	Kruskal	Kruskal	NNP
cord-309556-xv3413k1	163	29	-	-	HYPH
cord-309556-xv3413k1	163	30	Wallis	Wallis	NNP
cord-309556-xv3413k1	163	31	test	test	NN
cord-309556-xv3413k1	163	32	.	.	.
cord-309556-xv3413k1	164	1	To	to	TO
cord-309556-xv3413k1	164	2	identify	identify	VB
cord-309556-xv3413k1	164	3	age	age	NN
cord-309556-xv3413k1	164	4	-	-	HYPH
cord-309556-xv3413k1	164	5	associated	associate	VBN
cord-309556-xv3413k1	164	6	genes	gene	NNS
cord-309556-xv3413k1	164	7	,	,	,
cord-309556-xv3413k1	164	8	the	the	DT
cord-309556-xv3413k1	164	9	raw	raw	JJ
cord-309556-xv3413k1	164	10	counts	count	NNS
cord-309556-xv3413k1	164	11	values	value	NNS
cord-309556-xv3413k1	164	12	were	be	VBD
cord-309556-xv3413k1	164	13	analyzed	analyze	VBN
cord-309556-xv3413k1	164	14	by	by	IN
cord-309556-xv3413k1	164	15	DESeq2	DESeq2	NNP
cord-309556-xv3413k1	164	16	(	(	-LRB-
cord-309556-xv3413k1	164	17	v1.24.0	v1.24.0	NNP
cord-309556-xv3413k1	164	18	)	)	-RRB-
cord-309556-xv3413k1	164	19	22	22	CD
cord-309556-xv3413k1	164	20	,	,	,
cord-309556-xv3413k1	164	21	using	use	VBG
cord-309556-xv3413k1	164	22	the	the	DT
cord-309556-xv3413k1	164	23	likelihood	likelihood	NN
cord-309556-xv3413k1	164	24	ratio	ratio	NN
cord-309556-xv3413k1	164	25	test	test	NN
cord-309556-xv3413k1	164	26	(	(	-LRB-
cord-309556-xv3413k1	164	27	LRT	LRT	NNP
cord-309556-xv3413k1	164	28	)	)	-RRB-
cord-309556-xv3413k1	164	29	.	.	.
cord-309556-xv3413k1	165	1	Age	age	NN
cord-309556-xv3413k1	165	2	-	-	HYPH
cord-309556-xv3413k1	165	3	associated	associate	VBN
cord-309556-xv3413k1	165	4	genes	gene	NNS
cord-309556-xv3413k1	165	5	were	be	VBD
cord-309556-xv3413k1	165	6	determined	determine	VBN
cord-309556-xv3413k1	165	7	at	at	IN
cord-309556-xv3413k1	165	8	a	a	DT
cord-309556-xv3413k1	165	9	significance	significance	NN
cord-309556-xv3413k1	165	10	threshold	threshold	NN
cord-309556-xv3413k1	165	11	of	of	IN
cord-309556-xv3413k1	165	12	adjusted	adjust	VBN
cord-309556-xv3413k1	165	13	p	p	NN
cord-309556-xv3413k1	165	14	<	<	XX
cord-309556-xv3413k1	165	15	0.0001	0.0001	CD
cord-309556-xv3413k1	165	16	.	.	.
cord-309556-xv3413k1	166	1	Genes	gene	NNS
cord-309556-xv3413k1	166	2	passing	pass	VBG
cord-309556-xv3413k1	166	3	the	the	DT
cord-309556-xv3413k1	166	4	significance	significance	NN
cord-309556-xv3413k1	166	5	threshold	threshold	NN
cord-309556-xv3413k1	166	6	were	be	VBD
cord-309556-xv3413k1	166	7	then	then	RB
cord-309556-xv3413k1	166	8	scaled	scale	VBN
cord-309556-xv3413k1	166	9	to	to	IN
cord-309556-xv3413k1	166	10	z	z	NNS
cord-309556-xv3413k1	166	11	-	-	HYPH
cord-309556-xv3413k1	166	12	scores	score	NNS
cord-309556-xv3413k1	166	13	and	and	CC
cord-309556-xv3413k1	166	14	clustered	cluster	VBN
cord-309556-xv3413k1	166	15	using	use	VBG
cord-309556-xv3413k1	166	16	the	the	DT
cord-309556-xv3413k1	166	17	degPatterns	degPatterns	NNP
cord-309556-xv3413k1	166	18	function	function	VB
cord-309556-xv3413k1	166	19	from	from	IN
cord-309556-xv3413k1	166	20	the	the	DT
cord-309556-xv3413k1	166	21	R	r	NN
cord-309556-xv3413k1	166	22	package	package	NN
cord-309556-xv3413k1	166	23	DEGreport	degreport	NN
cord-309556-xv3413k1	166	24	(	(	-LRB-
cord-309556-xv3413k1	166	25	v1.20.0	v1.20.0	NNP
cord-309556-xv3413k1	166	26	)	)	-RRB-
cord-309556-xv3413k1	166	27	.	.	.
cord-309556-xv3413k1	167	1	Gene	gene	NN
cord-309556-xv3413k1	167	2	clusters	cluster	NNS
cord-309556-xv3413k1	167	3	with	with	IN
cord-309556-xv3413k1	167	4	progressive	progressive	JJ
cord-309556-xv3413k1	167	5	and	and	CC
cord-309556-xv3413k1	167	6	consistent	consistent	JJ
cord-309556-xv3413k1	167	7	trends	trend	NNS
cord-309556-xv3413k1	167	8	with	with	IN
cord-309556-xv3413k1	167	9	age	age	NN
cord-309556-xv3413k1	167	10	were	be	VBD
cord-309556-xv3413k1	167	11	retained	retain	VBN
cord-309556-xv3413k1	167	12	for	for	IN
cord-309556-xv3413k1	167	13	downstream	downstream	JJ
cord-309556-xv3413k1	167	14	analysis	analysis	NN
cord-309556-xv3413k1	167	15	.	.	.
cord-309556-xv3413k1	168	1	Gene	gene	NN
cord-309556-xv3413k1	168	2	ontology	ontology	NN
cord-309556-xv3413k1	168	3	and	and	CC
cord-309556-xv3413k1	168	4	pathway	pathway	NN
cord-309556-xv3413k1	168	5	enrichment	enrichment	NN
cord-309556-xv3413k1	168	6	analysis	analysis	NN
cord-309556-xv3413k1	168	7	was	be	VBD
cord-309556-xv3413k1	168	8	performed	perform	VBN
cord-309556-xv3413k1	168	9	using	use	VBG
cord-309556-xv3413k1	168	10	DAVID	DAVID	NNP
cord-309556-xv3413k1	168	11	(	(	-LRB-
cord-309556-xv3413k1	168	12	v6.8	v6.8	JJ
cord-309556-xv3413k1	168	13	)	)	-RRB-
cord-309556-xv3413k1	168	14	70	70	CD
cord-309556-xv3413k1	168	15	(	(	-LRB-
cord-309556-xv3413k1	168	16	https://david.ncifcrf.gov/	https://david.ncifcrf.gov/	$
cord-309556-xv3413k1	168	17	)	)	-RRB-
cord-309556-xv3413k1	168	18	,	,	,
cord-309556-xv3413k1	168	19	separating	separate	VBG
cord-309556-xv3413k1	168	20	the	the	DT
cord-309556-xv3413k1	168	21	age	age	NN
cord-309556-xv3413k1	168	22	-	-	HYPH
cord-309556-xv3413k1	168	23	associated	associate	VBN
cord-309556-xv3413k1	168	24	genes	gene	NNS
cord-309556-xv3413k1	168	25	into	into	IN
cord-309556-xv3413k1	168	26	the	the	DT
cord-309556-xv3413k1	168	27	two	two	CD
cord-309556-xv3413k1	168	28	clusters	cluster	NNS
cord-309556-xv3413k1	168	29	(	(	-LRB-
cord-309556-xv3413k1	168	30	increasing	increase	VBG
cord-309556-xv3413k1	168	31	or	or	CC
cord-309556-xv3413k1	168	32	decreasing	decrease	VBG
cord-309556-xv3413k1	168	33	with	with	IN
cord-309556-xv3413k1	168	34	age	age	NN
cord-309556-xv3413k1	168	35	)	)	-RRB-
cord-309556-xv3413k1	168	36	,	,	,
cord-309556-xv3413k1	168	37	as	as	IN
cord-309556-xv3413k1	168	38	described	describe	VBN
cord-309556-xv3413k1	168	39	above	above	RB
cord-309556-xv3413k1	168	40	.	.	.
cord-309556-xv3413k1	169	1	scRNA	scRNA	NNP
cord-309556-xv3413k1	169	2	-	-	HYPH
cord-309556-xv3413k1	169	3	seq	seq	NN
cord-309556-xv3413k1	169	4	data	datum	NNS
cord-309556-xv3413k1	169	5	were	be	VBD
cord-309556-xv3413k1	169	6	analyzed	analyze	VBN
cord-309556-xv3413k1	169	7	in	in	IN
cord-309556-xv3413k1	169	8	R	r	NN
cord-309556-xv3413k1	169	9	(	(	-LRB-
cord-309556-xv3413k1	169	10	v3.6.1	v3.6.1	NNP
cord-309556-xv3413k1	169	11	)	)	-RRB-
cord-309556-xv3413k1	169	12	using	use	VBG
cord-309556-xv3413k1	169	13	Seurat	Seurat	NNP
cord-309556-xv3413k1	169	14	71,72	71,72	CD
cord-309556-xv3413k1	169	15	and	and	CC
cord-309556-xv3413k1	169	16	custom	custom	NN
cord-309556-xv3413k1	169	17	scripts	script	NNS
cord-309556-xv3413k1	169	18	.	.	.
cord-309556-xv3413k1	170	1	Of	of	IN
cord-309556-xv3413k1	170	2	the	the	DT
cord-309556-xv3413k1	170	3	1285	1285	CD
cord-309556-xv3413k1	170	4	age	age	NN
cord-309556-xv3413k1	170	5	-	-	HYPH
cord-309556-xv3413k1	170	6	associated	associate	VBN
cord-309556-xv3413k1	170	7	genes	gene	NNS
cord-309556-xv3413k1	170	8	identified	identify	VBN
cord-309556-xv3413k1	170	9	from	from	IN
cord-309556-xv3413k1	170	10	GTEx	GTEx	NNP
cord-309556-xv3413k1	170	11	bulk	bulk	JJ
cord-309556-xv3413k1	170	12	transcriptomes	transcriptome	NNS
cord-309556-xv3413k1	170	13	,	,	,
cord-309556-xv3413k1	170	14	1049	1049	CD
cord-309556-xv3413k1	170	15	genes	gene	NNS
cord-309556-xv3413k1	170	16	were	be	VBD
cord-309556-xv3413k1	170	17	matched	match	VBN
cord-309556-xv3413k1	170	18	in	in	IN
cord-309556-xv3413k1	170	19	the	the	DT
cord-309556-xv3413k1	170	20	Tissue	Tissue	NNP
cord-309556-xv3413k1	170	21	Stability	Stability	NNP
cord-309556-xv3413k1	170	22	Cell	Cell	NNP
cord-309556-xv3413k1	170	23	Atlas	Atlas	NNP
cord-309556-xv3413k1	170	24	dataset	dataset	NN
cord-309556-xv3413k1	170	25	and	and	CC
cord-309556-xv3413k1	170	26	1021	1021	CD
cord-309556-xv3413k1	170	27	genes	gene	NNS
cord-309556-xv3413k1	170	28	were	be	VBD
cord-309556-xv3413k1	170	29	matched	match	VBN
cord-309556-xv3413k1	170	30	in	in	IN
cord-309556-xv3413k1	170	31	the	the	DT
cord-309556-xv3413k1	170	32	Human	Human	NNP
cord-309556-xv3413k1	170	33	Lung	Lung	NNP
cord-309556-xv3413k1	170	34	Cell	Cell	NNP
cord-309556-xv3413k1	170	35	Atlas	Atlas	NNP
cord-309556-xv3413k1	170	36	dataset	dataset	NN
cord-309556-xv3413k1	170	37	.	.	.
cord-309556-xv3413k1	171	1	To	to	TO
cord-309556-xv3413k1	171	2	determine	determine	VB
cord-309556-xv3413k1	171	3	the	the	DT
cord-309556-xv3413k1	171	4	percentage	percentage	NN
cord-309556-xv3413k1	171	5	of	of	IN
cord-309556-xv3413k1	171	6	cells	cell	NNS
cord-309556-xv3413k1	171	7	expressing	express	VBG
cord-309556-xv3413k1	171	8	a	a	DT
cord-309556-xv3413k1	171	9	given	give	VBN
cord-309556-xv3413k1	171	10	gene	gene	NN
cord-309556-xv3413k1	171	11	,	,	,
cord-309556-xv3413k1	171	12	the	the	DT
cord-309556-xv3413k1	171	13	expression	expression	NN
cord-309556-xv3413k1	171	14	matrices	matrix	NNS
cord-309556-xv3413k1	171	15	were	be	VBD
cord-309556-xv3413k1	171	16	converted	convert	VBN
cord-309556-xv3413k1	171	17	to	to	IN
cord-309556-xv3413k1	171	18	binary	binary	JJ
cord-309556-xv3413k1	171	19	matrices	matrix	NNS
cord-309556-xv3413k1	171	20	by	by	IN
cord-309556-xv3413k1	171	21	setting	set	VBG
cord-309556-xv3413k1	171	22	a	a	DT
cord-309556-xv3413k1	171	23	threshold	threshold	NN
cord-309556-xv3413k1	171	24	of	of	IN
cord-309556-xv3413k1	171	25	expression	expression	NN
cord-309556-xv3413k1	171	26	>	>	XX
cord-309556-xv3413k1	171	27	0	0	NFP
cord-309556-xv3413k1	171	28	.	.	.
cord-309556-xv3413k1	172	1	Cell	cell	NN
cord-309556-xv3413k1	172	2	typespecific	typespecific	NN
cord-309556-xv3413k1	172	3	expression	expression	NN
cord-309556-xv3413k1	172	4	frequencies	frequency	NNS
cord-309556-xv3413k1	172	5	for	for	IN
cord-309556-xv3413k1	172	6	each	each	DT
cord-309556-xv3413k1	172	7	gene	gene	NN
cord-309556-xv3413k1	172	8	were	be	VBD
cord-309556-xv3413k1	172	9	then	then	RB
cord-309556-xv3413k1	172	10	calculated	calculate	VBN
cord-309556-xv3413k1	172	11	using	use	VBG
cord-309556-xv3413k1	172	12	the	the	DT
cord-309556-xv3413k1	172	13	provided	provide	VBN
cord-309556-xv3413k1	172	14	cell	cell	NN
cord-309556-xv3413k1	172	15	type	type	NN
cord-309556-xv3413k1	172	16	annotations	annotation	NNS
cord-309556-xv3413k1	172	17	.	.	.
cord-309556-xv3413k1	173	1	To	to	TO
cord-309556-xv3413k1	173	2	identify	identify	VB
cord-309556-xv3413k1	173	3	genes	gene	NNS
cord-309556-xv3413k1	173	4	preferentially	preferentially	RB
cord-309556-xv3413k1	173	5	expressed	express	VBN
cord-309556-xv3413k1	173	6	in	in	IN
cord-309556-xv3413k1	173	7	a	a	DT
cord-309556-xv3413k1	173	8	specific	specific	JJ
cord-309556-xv3413k1	173	9	cell	cell	NN
cord-309556-xv3413k1	173	10	type	type	NN
cord-309556-xv3413k1	173	11	,	,	,
cord-309556-xv3413k1	173	12	we	-PRON-	PRP
cord-309556-xv3413k1	173	13	further	further	RB
cord-309556-xv3413k1	173	14	scaled	scale	VBD
cord-309556-xv3413k1	173	15	the	the	DT
cord-309556-xv3413k1	173	16	expression	expression	NN
cord-309556-xv3413k1	173	17	frequencies	frequency	NNS
cord-309556-xv3413k1	173	18	in	in	IN
cord-309556-xv3413k1	173	19	R	r	NN
cord-309556-xv3413k1	173	20	to	to	TO
cord-309556-xv3413k1	173	21	obtain	obtain	VB
cord-309556-xv3413k1	173	22	z	z	NN
cord-309556-xv3413k1	173	23	-	-	HYPH
cord-309556-xv3413k1	173	24	scores	score	NNS
cord-309556-xv3413k1	173	25	.	.	.
cord-309556-xv3413k1	174	1	Data	datum	NNS
cord-309556-xv3413k1	174	2	were	be	VBD
cord-309556-xv3413k1	174	3	visualized	visualize	VBN
cord-309556-xv3413k1	174	4	in	in	IN
cord-309556-xv3413k1	174	5	R	r	NN
cord-309556-xv3413k1	174	6	using	use	VBG
cord-309556-xv3413k1	174	7	the	the	DT
cord-309556-xv3413k1	174	8	NMF	NMF	NNP
cord-309556-xv3413k1	174	9	package	package	NN
cord-309556-xv3413k1	174	10	73	73	CD
cord-309556-xv3413k1	174	11	.	.	.
cord-309556-xv3413k1	175	1	Where	where	WRB
cord-309556-xv3413k1	175	2	applicable	applicable	JJ
cord-309556-xv3413k1	175	3	,	,	,
cord-309556-xv3413k1	175	4	gene	gene	NN
cord-309556-xv3413k1	175	5	ontology	ontology	NN
cord-309556-xv3413k1	175	6	analysis	analysis	NN
cord-309556-xv3413k1	175	7	was	be	VBD
cord-309556-xv3413k1	175	8	performed	perform	VBN
cord-309556-xv3413k1	175	9	with	with	IN
cord-309556-xv3413k1	175	10	DAVID	DAVID	NNP
cord-309556-xv3413k1	175	11	(	(	-LRB-
cord-309556-xv3413k1	175	12	v6.8	v6.8	JJ
cord-309556-xv3413k1	175	13	)	)	-RRB-
cord-309556-xv3413k1	175	14	70	70	CD
cord-309556-xv3413k1	175	15	,	,	,
cord-309556-xv3413k1	175	16	using	use	VBG
cord-309556-xv3413k1	175	17	genes	gene	NNS
cord-309556-xv3413k1	175	18	with	with	IN
cord-309556-xv3413k1	175	19	z	z	NN
cord-309556-xv3413k1	175	20	-	-	HYPH
cord-309556-xv3413k1	175	21	score	score	NN
cord-309556-xv3413k1	175	22	>	>	XX
cord-309556-xv3413k1	175	23	2	2	CD
cord-309556-xv3413k1	175	24	in	in	IN
cord-309556-xv3413k1	175	25	the	the	DT
cord-309556-xv3413k1	175	26	cell	cell	NN
cord-309556-xv3413k1	175	27	type	type	NN
cord-309556-xv3413k1	175	28	of	of	IN
cord-309556-xv3413k1	175	29	interest	interest	NN
cord-309556-xv3413k1	175	30	for	for	IN
cord-309556-xv3413k1	175	31	analysis	analysis	NN
cord-309556-xv3413k1	175	32	.	.	.
cord-309556-xv3413k1	176	1	To	to	TO
cord-309556-xv3413k1	176	2	infer	infer	VB
cord-309556-xv3413k1	176	3	the	the	DT
cord-309556-xv3413k1	176	4	cellular	cellular	JJ
cord-309556-xv3413k1	176	5	composition	composition	NN
cord-309556-xv3413k1	176	6	of	of	IN
cord-309556-xv3413k1	176	7	each	each	DT
cord-309556-xv3413k1	176	8	lung	lung	NN
cord-309556-xv3413k1	176	9	sample	sample	NN
cord-309556-xv3413k1	176	10	,	,	,
cord-309556-xv3413k1	176	11	we	-PRON-	PRP
cord-309556-xv3413k1	176	12	analyzed	analyze	VBD
cord-309556-xv3413k1	176	13	the	the	DT
cord-309556-xv3413k1	176	14	TPM	TPM	NNP
cord-309556-xv3413k1	176	15	expression	expression	NN
cord-309556-xv3413k1	176	16	matrices	matrix	NNS
cord-309556-xv3413k1	176	17	using	use	VBG
cord-309556-xv3413k1	176	18	the	the	DT
cord-309556-xv3413k1	176	19	xCell	xCell	NNP
cord-309556-xv3413k1	176	20	algorithm	algorithm	NN
cord-309556-xv3413k1	176	21	45	45	CD
cord-309556-xv3413k1	176	22	.	.	.
cord-309556-xv3413k1	177	1	The	the	DT
cord-309556-xv3413k1	177	2	resultant	resultant	JJ
cord-309556-xv3413k1	177	3	cell	cell	NN
cord-309556-xv3413k1	177	4	type	type	NN
cord-309556-xv3413k1	177	5	enrichment	enrichment	NN
cord-309556-xv3413k1	177	6	tables	table	NNS
cord-309556-xv3413k1	177	7	were	be	VBD
cord-309556-xv3413k1	177	8	analyzed	analyze	VBN
cord-309556-xv3413k1	177	9	in	in	IN
cord-309556-xv3413k1	177	10	R.	R.	NNP
cord-309556-xv3413k1	178	1	For	for	IN
cord-309556-xv3413k1	178	2	data	datum	NNS
cord-309556-xv3413k1	178	3	visualization	visualization	NN
cord-309556-xv3413k1	178	4	,	,	,
cord-309556-xv3413k1	178	5	cell	cell	NN
cord-309556-xv3413k1	178	6	type	type	NN
cord-309556-xv3413k1	178	7	enrichment	enrichment	NN
cord-309556-xv3413k1	178	8	scores	score	NNS
cord-309556-xv3413k1	178	9	were	be	VBD
cord-309556-xv3413k1	178	10	scaled	scale	VBN
cord-309556-xv3413k1	178	11	to	to	IN
cord-309556-xv3413k1	178	12	z	z	NNS
cord-309556-xv3413k1	178	13	-	-	HYPH
cord-309556-xv3413k1	178	14	scores	score	NNS
cord-309556-xv3413k1	178	15	,	,	,
cord-309556-xv3413k1	178	16	and	and	CC
cord-309556-xv3413k1	178	17	the	the	DT
cord-309556-xv3413k1	178	18	median	median	JJ
cord-309556-xv3413k1	178	19	zscore	zscore	NN
cord-309556-xv3413k1	178	20	for	for	IN
cord-309556-xv3413k1	178	21	each	each	DT
cord-309556-xv3413k1	178	22	age	age	NN
cord-309556-xv3413k1	178	23	group	group	NN
cord-309556-xv3413k1	178	24	was	be	VBD
cord-309556-xv3413k1	178	25	expressed	express	VBN
cord-309556-xv3413k1	178	26	as	as	IN
cord-309556-xv3413k1	178	27	a	a	DT
cord-309556-xv3413k1	178	28	heatmap	heatmap	NN
cord-309556-xv3413k1	178	29	,	,	,
cord-309556-xv3413k1	178	30	using	use	VBG
cord-309556-xv3413k1	178	31	the	the	DT
cord-309556-xv3413k1	178	32	superheat	superheat	NN
cord-309556-xv3413k1	178	33	package	package	NN
cord-309556-xv3413k1	178	34	74	74	CD
cord-309556-xv3413k1	178	35	.	.	.
cord-309556-xv3413k1	179	1	Ageassociation	Ageassociation	NNP
cord-309556-xv3413k1	179	2	was	be	VBD
cord-309556-xv3413k1	179	3	assessed	assess	VBN
cord-309556-xv3413k1	179	4	across	across	IN
cord-309556-xv3413k1	179	5	all	all	DT
cord-309556-xv3413k1	179	6	age	age	NN
cord-309556-xv3413k1	179	7	groups	group	NNS
cord-309556-xv3413k1	179	8	by	by	IN
cord-309556-xv3413k1	179	9	Kruskal	Kruskal	NNP
cord-309556-xv3413k1	179	10	-	-	HYPH
cord-309556-xv3413k1	179	11	Wallis	Wallis	NNP
cord-309556-xv3413k1	179	12	test	test	NN
cord-309556-xv3413k1	179	13	.	.	.
cord-309556-xv3413k1	180	1	To	to	TO
cord-309556-xv3413k1	180	2	assess	assess	VB
cord-309556-xv3413k1	180	3	whether	whether	IN
cord-309556-xv3413k1	180	4	any	any	DT
cord-309556-xv3413k1	180	5	age	age	NN
cord-309556-xv3413k1	180	6	-	-	HYPH
cord-309556-xv3413k1	180	7	associated	associate	VBN
cord-309556-xv3413k1	180	8	genes	gene	NNS
cord-309556-xv3413k1	180	9	affect	affect	VBP
cord-309556-xv3413k1	180	10	host	host	NN
cord-309556-xv3413k1	180	11	responses	response	NNS
cord-309556-xv3413k1	180	12	to	to	IN
cord-309556-xv3413k1	180	13	SARS	SARS	NNP
cord-309556-xv3413k1	180	14	-	-	HYPH
cord-309556-xv3413k1	180	15	CoV	CoV	NNP
cord-309556-xv3413k1	180	16	(	(	-LRB-
cord-309556-xv3413k1	180	17	a	a	DT
cord-309556-xv3413k1	180	18	coronavirus	coronavirus	NN
cord-309556-xv3413k1	180	19	related	relate	VBN
cord-309556-xv3413k1	180	20	to	to	IN
cord-309556-xv3413k1	180	21	SARS	SARS	NNP
cord-309556-xv3413k1	180	22	-	-	HYPH
cord-309556-xv3413k1	180	23	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	180	24	)	)	-RRB-
cord-309556-xv3413k1	180	25	,	,	,
cord-309556-xv3413k1	180	26	we	-PRON-	PRP
cord-309556-xv3413k1	180	27	analyzed	analyze	VBD
cord-309556-xv3413k1	180	28	the	the	DT
cord-309556-xv3413k1	180	29	data	datum	NNS
cord-309556-xv3413k1	180	30	from	from	IN
cord-309556-xv3413k1	180	31	a	a	DT
cord-309556-xv3413k1	180	32	published	publish	VBN
cord-309556-xv3413k1	180	33	siRNA	siRNA	NNP
cord-309556-xv3413k1	180	34	screen	screen	NN
cord-309556-xv3413k1	180	35	of	of	IN
cord-309556-xv3413k1	180	36	host	host	NN
cord-309556-xv3413k1	180	37	factors	factor	NNS
cord-309556-xv3413k1	180	38	influencing	influence	VBG
cord-309556-xv3413k1	180	39	SARS	SARS	NNP
cord-309556-xv3413k1	180	40	-	-	HYPH
cord-309556-xv3413k1	180	41	CoV	CoV	NNP
cord-309556-xv3413k1	180	42	63	63	CD
cord-309556-xv3413k1	181	1	(	(	-LRB-
cord-309556-xv3413k1	181	2	Data	datum	NNS
cord-309556-xv3413k1	181	3	Set	Set	VBD
cord-309556-xv3413k1	181	4	S1	S1	NNP
cord-309556-xv3413k1	181	5	in	in	IN
cord-309556-xv3413k1	181	6	the	the	DT
cord-309556-xv3413k1	181	7	publication	publication	NN
cord-309556-xv3413k1	181	8	;	;	:
cord-309556-xv3413k1	181	9	accessed	access	VBN
cord-309556-xv3413k1	181	10	on	on	IN
cord-309556-xv3413k1	181	11	March	March	NNP
cord-309556-xv3413k1	181	12	20	20	CD
cord-309556-xv3413k1	181	13	,	,	,
cord-309556-xv3413k1	181	14	2020	2020	CD
cord-309556-xv3413k1	181	15	)	)	-RRB-
cord-309556-xv3413k1	181	16	.	.	.
cord-309556-xv3413k1	182	1	For	for	IN
cord-309556-xv3413k1	182	2	data	datum	NNS
cord-309556-xv3413k1	182	3	visualization	visualization	NN
cord-309556-xv3413k1	182	4	,	,	,
cord-309556-xv3413k1	182	5	each	each	DT
cord-309556-xv3413k1	182	6	point	point	NN
cord-309556-xv3413k1	182	7	corresponding	correspond	VBG
cord-309556-xv3413k1	182	8	to	to	IN
cord-309556-xv3413k1	182	9	a	a	DT
cord-309556-xv3413k1	182	10	target	target	NN
cord-309556-xv3413k1	182	11	gene	gene	NN
cord-309556-xv3413k1	182	12	was	be	VBD
cord-309556-xv3413k1	182	13	size	size	NN
cord-309556-xv3413k1	182	14	-	-	HYPH
cord-309556-xv3413k1	182	15	scaled	scale	VBN
cord-309556-xv3413k1	182	16	and	and	CC
cord-309556-xv3413k1	182	17	color	color	NN
cord-309556-xv3413k1	182	18	-	-	HYPH
cord-309556-xv3413k1	182	19	coded	code	VBN
cord-309556-xv3413k1	182	20	according	accord	VBG
cord-309556-xv3413k1	182	21	to	to	IN
cord-309556-xv3413k1	182	22	the	the	DT
cord-309556-xv3413k1	182	23	age	age	NN
cord-309556-xv3413k1	182	24	-	-	HYPH
cord-309556-xv3413k1	182	25	association	association	NN
cord-309556-xv3413k1	182	26	statistical	statistical	JJ
cord-309556-xv3413k1	182	27	analyses	analysis	NNS
cord-309556-xv3413k1	182	28	described	describe	VBN
cord-309556-xv3413k1	182	29	above	above	RB
cord-309556-xv3413k1	182	30	.	.	.
cord-309556-xv3413k1	183	1	To	to	TO
cord-309556-xv3413k1	183	2	assess	assess	VB
cord-309556-xv3413k1	183	3	whether	whether	IN
cord-309556-xv3413k1	183	4	any	any	DT
cord-309556-xv3413k1	183	5	lung	lung	NN
cord-309556-xv3413k1	183	6	age	age	NN
cord-309556-xv3413k1	183	7	-	-	HYPH
cord-309556-xv3413k1	183	8	associated	associate	VBN
cord-309556-xv3413k1	183	9	genes	gene	NNS
cord-309556-xv3413k1	183	10	encode	encode	VBP
cord-309556-xv3413k1	183	11	proteins	protein	NNS
cord-309556-xv3413k1	183	12	that	that	WDT
cord-309556-xv3413k1	183	13	interact	interact	VBP
cord-309556-xv3413k1	183	14	with	with	IN
cord-309556-xv3413k1	183	15	the	the	DT
cord-309556-xv3413k1	183	16	SARS	SARS	NNP
cord-309556-xv3413k1	183	17	-	-	HYPH
cord-309556-xv3413k1	183	18	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	183	19	proteome	proteome	NN
cord-309556-xv3413k1	183	20	,	,	,
cord-309556-xv3413k1	183	21	we	-PRON-	PRP
cord-309556-xv3413k1	183	22	compiled	compile	VBD
cord-309556-xv3413k1	183	23	the	the	DT
cord-309556-xv3413k1	183	24	data	datum	NNS
cord-309556-xv3413k1	183	25	from	from	IN
cord-309556-xv3413k1	183	26	a	a	DT
cord-309556-xv3413k1	183	27	preprint	preprint	NN
cord-309556-xv3413k1	183	28	manuscript	manuscript	NN
cord-309556-xv3413k1	183	29	detailing	detail	VBG
cord-309556-xv3413k1	183	30	the	the	DT
cord-309556-xv3413k1	183	31	human	human	JJ
cord-309556-xv3413k1	183	32	host	host	NN
cord-309556-xv3413k1	183	33	factors	factor	NNS
cord-309556-xv3413k1	183	34	that	that	WDT
cord-309556-xv3413k1	183	35	interact	interact	VBP
cord-309556-xv3413k1	183	36	with	with	IN
cord-309556-xv3413k1	183	37	27	27	CD
cord-309556-xv3413k1	183	38	different	different	JJ
cord-309556-xv3413k1	183	39	proteins	protein	NNS
cord-309556-xv3413k1	183	40	in	in	IN
cord-309556-xv3413k1	183	41	the	the	DT
cord-309556-xv3413k1	183	42	SARS	SARS	NNP
cord-309556-xv3413k1	183	43	-	-	HYPH
cord-309556-xv3413k1	183	44	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	183	45	proteome	proteome	NN
cord-309556-xv3413k1	183	46	64	64	CD
cord-309556-xv3413k1	183	47	(	(	-LRB-
cord-309556-xv3413k1	183	48	accessed	access	VBN
cord-309556-xv3413k1	183	49	on	on	IN
cord-309556-xv3413k1	183	50	March	March	NNP
cord-309556-xv3413k1	183	51	23	23	CD
cord-309556-xv3413k1	183	52	,	,	,
cord-309556-xv3413k1	183	53	2020	2020	CD
cord-309556-xv3413k1	183	54	)	)	-RRB-
cord-309556-xv3413k1	183	55	.	.	.
cord-309556-xv3413k1	184	1	To	to	TO
cord-309556-xv3413k1	184	2	assess	assess	VB
cord-309556-xv3413k1	184	3	whether	whether	IN
cord-309556-xv3413k1	184	4	the	the	DT
cord-309556-xv3413k1	184	5	expression	expression	NN
cord-309556-xv3413k1	184	6	of	of	IN
cord-309556-xv3413k1	184	7	lung	lung	NN
cord-309556-xv3413k1	184	8	age	age	NN
cord-309556-xv3413k1	184	9	-	-	HYPH
cord-309556-xv3413k1	184	10	associated	associate	VBN
cord-309556-xv3413k1	184	11	genes	gene	NNS
cord-309556-xv3413k1	184	12	is	be	VBZ
cord-309556-xv3413k1	184	13	influenced	influence	VBN
cord-309556-xv3413k1	184	14	by	by	IN
cord-309556-xv3413k1	184	15	SARS	SARS	NNP
cord-309556-xv3413k1	184	16	-	-	HYPH
cord-309556-xv3413k1	184	17	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	184	18	infection	infection	NN
cord-309556-xv3413k1	184	19	,	,	,
cord-309556-xv3413k1	184	20	we	-PRON-	PRP
cord-309556-xv3413k1	184	21	utilized	utilize	VBD
cord-309556-xv3413k1	184	22	the	the	DT
cord-309556-xv3413k1	184	23	data	datum	NNS
cord-309556-xv3413k1	184	24	from	from	IN
cord-309556-xv3413k1	184	25	a	a	DT
cord-309556-xv3413k1	184	26	preprint	preprint	NN
cord-309556-xv3413k1	184	27	manuscript	manuscript	NN
cord-309556-xv3413k1	184	28	detailing	detail	VBG
cord-309556-xv3413k1	184	29	the	the	DT
cord-309556-xv3413k1	184	30	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	184	31	response	response	NN
cord-309556-xv3413k1	184	32	to	to	IN
cord-309556-xv3413k1	184	33	SARS	SARS	NNP
cord-309556-xv3413k1	184	34	-	-	HYPH
cord-309556-xv3413k1	184	35	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	184	36	infection	infection	NN
cord-309556-xv3413k1	184	37	68	68	CD
cord-309556-xv3413k1	184	38	,	,	,
cord-309556-xv3413k1	184	39	from	from	IN
cord-309556-xv3413k1	184	40	the	the	DT
cord-309556-xv3413k1	184	41	Gene	Gene	NNP
cord-309556-xv3413k1	184	42	Expression	Expression	NNP
cord-309556-xv3413k1	184	43	Omnibus	Omnibus	NNP
cord-309556-xv3413k1	184	44	(	(	-LRB-
cord-309556-xv3413k1	184	45	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE147507	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=gse147507	NN
cord-309556-xv3413k1	184	46	)	)	-RRB-
cord-309556-xv3413k1	184	47	(	(	-LRB-
cord-309556-xv3413k1	184	48	accessed	access	VBN
cord-309556-xv3413k1	184	49	on	on	IN
cord-309556-xv3413k1	184	50	April	April	NNP
cord-309556-xv3413k1	184	51	13	13	CD
cord-309556-xv3413k1	184	52	,	,	,
cord-309556-xv3413k1	184	53	2020	2020	CD
cord-309556-xv3413k1	184	54	)	)	-RRB-
cord-309556-xv3413k1	184	55	.	.	.
cord-309556-xv3413k1	185	1	Differentially	differentially	RB
cord-309556-xv3413k1	185	2	expressed	express	VBN
cord-309556-xv3413k1	185	3	genes	gene	NNS
cord-309556-xv3413k1	185	4	were	be	VBD
cord-309556-xv3413k1	185	5	determined	determine	VBN
cord-309556-xv3413k1	185	6	using	use	VBG
cord-309556-xv3413k1	185	7	the	the	DT
cord-309556-xv3413k1	185	8	Wald	Wald	NNP
cord-309556-xv3413k1	185	9	test	test	NN
cord-309556-xv3413k1	185	10	in	in	IN
cord-309556-xv3413k1	185	11	DESeq2	DESeq2	NNP
cord-309556-xv3413k1	185	12	(	(	-LRB-
cord-309556-xv3413k1	185	13	v1.24.0	v1.24.0	NN
cord-309556-xv3413k1	185	14	)	)	-RRB-
cord-309556-xv3413k1	185	15	22	22	CD
cord-309556-xv3413k1	185	16	comparing	compare	VBG
cord-309556-xv3413k1	185	17	SARS	SARS	NNP
cord-309556-xv3413k1	185	18	-	-	HYPH
cord-309556-xv3413k1	185	19	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	185	20	infected	infected	JJ
cord-309556-xv3413k1	185	21	cells	cell	NNS
cord-309556-xv3413k1	185	22	to	to	IN
cord-309556-xv3413k1	185	23	batch	batch	VB
cord-309556-xv3413k1	185	24	-	-	HYPH
cord-309556-xv3413k1	185	25	matched	match	VBN
cord-309556-xv3413k1	185	26	mock	mock	JJ
cord-309556-xv3413k1	185	27	controls	control	NNS
cord-309556-xv3413k1	185	28	,	,	,
cord-309556-xv3413k1	185	29	with	with	IN
cord-309556-xv3413k1	185	30	a	a	DT
cord-309556-xv3413k1	185	31	significance	significance	NN
cord-309556-xv3413k1	185	32	threshold	threshold	NN
cord-309556-xv3413k1	185	33	of	of	IN
cord-309556-xv3413k1	185	34	adjusted	adjust	VBN
cord-309556-xv3413k1	185	35	p	p	NN
cord-309556-xv3413k1	185	36	<	<	XX
cord-309556-xv3413k1	185	37	0.05	0.05	CD
cord-309556-xv3413k1	185	38	.	.	.
cord-309556-xv3413k1	186	1	Of	of	IN
cord-309556-xv3413k1	186	2	the	the	DT
cord-309556-xv3413k1	186	3	1285	1285	CD
cord-309556-xv3413k1	186	4	age	age	NN
cord-309556-xv3413k1	186	5	-	-	HYPH
cord-309556-xv3413k1	186	6	associated	associate	VBN
cord-309556-xv3413k1	186	7	genes	gene	NNS
cord-309556-xv3413k1	186	8	,	,	,
cord-309556-xv3413k1	186	9	988	988	CD
cord-309556-xv3413k1	186	10	genes	gene	NNS
cord-309556-xv3413k1	186	11	were	be	VBD
cord-309556-xv3413k1	186	12	matched	match	VBN
cord-309556-xv3413k1	186	13	to	to	IN
cord-309556-xv3413k1	186	14	the	the	DT
cord-309556-xv3413k1	186	15	RNA	RNA	NNP
cord-309556-xv3413k1	186	16	-	-	HYPH
cord-309556-xv3413k1	186	17	seq	seq	NN
cord-309556-xv3413k1	186	18	dataset	dataset	NN
cord-309556-xv3413k1	186	19	.	.	.
cord-309556-xv3413k1	187	1	Statistical	statistical	JJ
cord-309556-xv3413k1	187	2	significance	significance	NN
cord-309556-xv3413k1	187	3	of	of	IN
cord-309556-xv3413k1	187	4	overlaps	overlap	NNS
cord-309556-xv3413k1	187	5	between	between	IN
cord-309556-xv3413k1	187	6	the	the	DT
cord-309556-xv3413k1	187	7	gene	gene	NN
cord-309556-xv3413k1	187	8	sets	set	NNS
cord-309556-xv3413k1	187	9	was	be	VBD
cord-309556-xv3413k1	187	10	assessed	assess	VBN
cord-309556-xv3413k1	187	11	by	by	IN
cord-309556-xv3413k1	187	12	hypergeometric	hypergeometric	JJ
cord-309556-xv3413k1	187	13	test	test	NN
cord-309556-xv3413k1	187	14	,	,	,
cord-309556-xv3413k1	187	15	assuming	assume	VBG
cord-309556-xv3413k1	187	16	21,797	21,797	CD
cord-309556-xv3413k1	187	17	total	total	JJ
cord-309556-xv3413k1	187	18	genes	gene	NNS
cord-309556-xv3413k1	187	19	as	as	IN
cord-309556-xv3413k1	187	20	annotated	annotate	VBN
cord-309556-xv3413k1	187	21	in	in	IN
cord-309556-xv3413k1	187	22	the	the	DT
cord-309556-xv3413k1	187	23	RNA	RNA	NNP
cord-309556-xv3413k1	187	24	-	-	HYPH
cord-309556-xv3413k1	187	25	seq	seq	NN
cord-309556-xv3413k1	187	26	dataset	dataset	NN
cord-309556-xv3413k1	187	27	and	and	CC
cord-309556-xv3413k1	187	28	988	988	CD
cord-309556-xv3413k1	187	29	age	age	NN
cord-309556-xv3413k1	187	30	-	-	HYPH
cord-309556-xv3413k1	187	31	associated	associate	VBN
cord-309556-xv3413k1	187	32	genes	gene	NNS
cord-309556-xv3413k1	187	33	.	.	.
cord-309556-xv3413k1	188	1	Statistical	statistical	JJ
cord-309556-xv3413k1	188	2	significance	significance	NN
cord-309556-xv3413k1	188	3	of	of	IN
cord-309556-xv3413k1	188	4	the	the	DT
cord-309556-xv3413k1	188	5	association	association	NN
cord-309556-xv3413k1	188	6	between	between	IN
cord-309556-xv3413k1	188	7	the	the	DT
cord-309556-xv3413k1	188	8	directionality	directionality	NN
cord-309556-xv3413k1	188	9	of	of	IN
cord-309556-xv3413k1	188	10	SARS	SARS	NNP
cord-309556-xv3413k1	188	11	-	-	HYPH
cord-309556-xv3413k1	188	12	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	188	13	regulation	regulation	NN
cord-309556-xv3413k1	188	14	and	and	CC
cord-309556-xv3413k1	188	15	the	the	DT
cord-309556-xv3413k1	188	16	directionality	directionality	NN
cord-309556-xv3413k1	188	17	of	of	IN
cord-309556-xv3413k1	188	18	age	age	NN
cord-309556-xv3413k1	188	19	-	-	HYPH
cord-309556-xv3413k1	188	20	association	association	NN
cord-309556-xv3413k1	188	21	was	be	VBD
cord-309556-xv3413k1	188	22	assessed	assess	VBN
cord-309556-xv3413k1	188	23	by	by	IN
cord-309556-xv3413k1	188	24	two	two	CD
cord-309556-xv3413k1	188	25	-	-	HYPH
cord-309556-xv3413k1	188	26	tailed	tailed	JJ
cord-309556-xv3413k1	188	27	Fischer	Fischer	NNP
cord-309556-xv3413k1	188	28	's	's	POS
cord-309556-xv3413k1	188	29	exact	exact	JJ
cord-309556-xv3413k1	188	30	test	test	NN
cord-309556-xv3413k1	188	31	.	.	.
cord-309556-xv3413k1	189	1	Gene	gene	NN
cord-309556-xv3413k1	189	2	ontology	ontology	NN
cord-309556-xv3413k1	189	3	and	and	CC
cord-309556-xv3413k1	189	4	pathway	pathway	NN
cord-309556-xv3413k1	189	5	enrichment	enrichment	NN
cord-309556-xv3413k1	189	6	analysis	analysis	NN
cord-309556-xv3413k1	189	7	was	be	VBD
cord-309556-xv3413k1	189	8	performed	perform	VBN
cord-309556-xv3413k1	189	9	using	use	VBG
cord-309556-xv3413k1	189	10	DAVID	DAVID	NNP
cord-309556-xv3413k1	189	11	(	(	-LRB-
cord-309556-xv3413k1	189	12	v6.8	v6.8	JJ
cord-309556-xv3413k1	189	13	)	)	-RRB-
cord-309556-xv3413k1	189	14	70	70	CD
cord-309556-xv3413k1	189	15	(	(	-LRB-
cord-309556-xv3413k1	189	16	https://david.ncifcrf.gov/	https://david.ncifcrf.gov/	NFP
cord-309556-xv3413k1	189	17	)	)	-RRB-
cord-309556-xv3413k1	189	18	.	.	.
cord-309556-xv3413k1	190	1	Comprehensive	comprehensive	JJ
cord-309556-xv3413k1	190	2	information	information	NN
cord-309556-xv3413k1	190	3	on	on	IN
cord-309556-xv3413k1	190	4	the	the	DT
cord-309556-xv3413k1	190	5	statistical	statistical	JJ
cord-309556-xv3413k1	190	6	analyses	analysis	NNS
cord-309556-xv3413k1	190	7	used	use	VBN
cord-309556-xv3413k1	190	8	are	be	VBP
cord-309556-xv3413k1	190	9	included	include	VBN
cord-309556-xv3413k1	190	10	in	in	IN
cord-309556-xv3413k1	190	11	various	various	JJ
cord-309556-xv3413k1	190	12	places	place	NNS
cord-309556-xv3413k1	190	13	,	,	,
cord-309556-xv3413k1	190	14	including	include	VBG
cord-309556-xv3413k1	190	15	the	the	DT
cord-309556-xv3413k1	190	16	figures	figure	NNS
cord-309556-xv3413k1	190	17	,	,	,
cord-309556-xv3413k1	190	18	figure	figure	NN
cord-309556-xv3413k1	190	19	legends	legend	NNS
cord-309556-xv3413k1	190	20	and	and	CC
cord-309556-xv3413k1	190	21	results	result	NNS
cord-309556-xv3413k1	190	22	,	,	,
cord-309556-xv3413k1	190	23	where	where	WRB
cord-309556-xv3413k1	190	24	the	the	DT
cord-309556-xv3413k1	190	25	methods	method	NNS
cord-309556-xv3413k1	190	26	,	,	,
cord-309556-xv3413k1	190	27	significance	significance	NN
cord-309556-xv3413k1	190	28	,	,	,
cord-309556-xv3413k1	190	29	p	p	NN
cord-309556-xv3413k1	190	30	-	-	HYPH
cord-309556-xv3413k1	190	31	values	value	NNS
cord-309556-xv3413k1	190	32	and/or	and/or	CC
cord-309556-xv3413k1	190	33	tails	tail	NNS
cord-309556-xv3413k1	190	34	are	be	VBP
cord-309556-xv3413k1	190	35	described	describe	VBN
cord-309556-xv3413k1	190	36	.	.	.
cord-309556-xv3413k1	191	1	All	all	DT
cord-309556-xv3413k1	191	2	error	error	NN
cord-309556-xv3413k1	191	3	bars	bar	NNS
cord-309556-xv3413k1	191	4	have	have	VBP
cord-309556-xv3413k1	191	5	been	be	VBN
cord-309556-xv3413k1	191	6	defined	define	VBN
cord-309556-xv3413k1	191	7	in	in	IN
cord-309556-xv3413k1	191	8	the	the	DT
cord-309556-xv3413k1	191	9	figure	figure	NN
cord-309556-xv3413k1	191	10	legends	legend	NNS
cord-309556-xv3413k1	191	11	or	or	CC
cord-309556-xv3413k1	191	12	methods	method	NNS
cord-309556-xv3413k1	191	13	.	.	.
cord-309556-xv3413k1	192	1	Codes	code	NNS
cord-309556-xv3413k1	192	2	used	use	VBN
cord-309556-xv3413k1	192	3	for	for	IN
cord-309556-xv3413k1	192	4	data	datum	NNS
cord-309556-xv3413k1	192	5	analysis	analysis	NN
cord-309556-xv3413k1	192	6	or	or	CC
cord-309556-xv3413k1	192	7	generation	generation	NN
cord-309556-xv3413k1	192	8	of	of	IN
cord-309556-xv3413k1	192	9	the	the	DT
cord-309556-xv3413k1	192	10	figures	figure	NNS
cord-309556-xv3413k1	192	11	related	relate	VBN
cord-309556-xv3413k1	192	12	to	to	IN
cord-309556-xv3413k1	192	13	this	this	DT
cord-309556-xv3413k1	192	14	study	study	NN
cord-309556-xv3413k1	192	15	are	be	VBP
cord-309556-xv3413k1	192	16	available	available	JJ
cord-309556-xv3413k1	192	17	upon	upon	IN
cord-309556-xv3413k1	192	18	request	request	NN
cord-309556-xv3413k1	192	19	to	to	IN
cord-309556-xv3413k1	192	20	the	the	DT
cord-309556-xv3413k1	192	21	corresponding	correspond	VBG
cord-309556-xv3413k1	192	22	author	author	NN
cord-309556-xv3413k1	192	23	and	and	CC
cord-309556-xv3413k1	192	24	will	will	MD
cord-309556-xv3413k1	192	25	be	be	VB
cord-309556-xv3413k1	192	26	deposited	deposit	VBN
cord-309556-xv3413k1	192	27	to	to	IN
cord-309556-xv3413k1	192	28	GitHub	GitHub	NNP
cord-309556-xv3413k1	192	29	upon	upon	IN
cord-309556-xv3413k1	192	30	publication	publication	NN
cord-309556-xv3413k1	192	31	for	for	IN
cord-309556-xv3413k1	192	32	free	free	JJ
cord-309556-xv3413k1	192	33	public	public	JJ
cord-309556-xv3413k1	192	34	access	access	NN
cord-309556-xv3413k1	192	35	.	.	.
cord-309556-xv3413k1	193	1	All	all	DT
cord-309556-xv3413k1	193	2	relevant	relevant	JJ
cord-309556-xv3413k1	193	3	processed	process	VBN
cord-309556-xv3413k1	193	4	data	datum	NNS
cord-309556-xv3413k1	193	5	generated	generate	VBN
cord-309556-xv3413k1	193	6	during	during	IN
cord-309556-xv3413k1	193	7	this	this	DT
cord-309556-xv3413k1	193	8	study	study	NN
cord-309556-xv3413k1	193	9	are	be	VBP
cord-309556-xv3413k1	193	10	included	include	VBN
cord-309556-xv3413k1	193	11	in	in	IN
cord-309556-xv3413k1	193	12	this	this	DT
cord-309556-xv3413k1	193	13	article	article	NN
cord-309556-xv3413k1	193	14	and	and	CC
cord-309556-xv3413k1	193	15	its	-PRON-	PRP$
cord-309556-xv3413k1	193	16	supplementary	supplementary	JJ
cord-309556-xv3413k1	193	17	information	information	NN
cord-309556-xv3413k1	193	18	files	file	NNS
cord-309556-xv3413k1	193	19	.	.	.
cord-309556-xv3413k1	194	1	Raw	raw	JJ
cord-309556-xv3413k1	194	2	data	datum	NNS
cord-309556-xv3413k1	194	3	are	be	VBP
cord-309556-xv3413k1	194	4	from	from	IN
cord-309556-xv3413k1	194	5	various	various	JJ
cord-309556-xv3413k1	194	6	sources	source	NNS
cord-309556-xv3413k1	194	7	as	as	IN
cord-309556-xv3413k1	194	8	described	describe	VBN
cord-309556-xv3413k1	194	9	above	above	RB
cord-309556-xv3413k1	194	10	.	.	.
cord-309556-xv3413k1	195	1	All	all	DT
cord-309556-xv3413k1	195	2	data	datum	NNS
cord-309556-xv3413k1	195	3	and	and	CC
cord-309556-xv3413k1	195	4	resources	resource	NNS
cord-309556-xv3413k1	195	5	related	relate	VBN
cord-309556-xv3413k1	195	6	to	to	IN
cord-309556-xv3413k1	195	7	this	this	DT
cord-309556-xv3413k1	195	8	study	study	NN
cord-309556-xv3413k1	195	9	are	be	VBP
cord-309556-xv3413k1	195	10	freely	freely	RB
cord-309556-xv3413k1	195	11	available	available	JJ
cord-309556-xv3413k1	195	12	upon	upon	IN
cord-309556-xv3413k1	195	13	request	request	NN
cord-309556-xv3413k1	195	14	to	to	IN
cord-309556-xv3413k1	195	15	the	the	DT
cord-309556-xv3413k1	195	16	corresponding	correspond	VBG
cord-309556-xv3413k1	195	17	author	author	NN
cord-309556-xv3413k1	195	18	.	.	.
cord-309556-xv3413k1	196	1	Tables	table	NNS
cord-309556-xv3413k1	196	2	  	  	_SP
cord-309556-xv3413k1	196	3	Table	table	NN
cord-309556-xv3413k1	196	4	S1	s1	NN
cord-309556-xv3413k1	196	5	:	:	:
cord-309556-xv3413k1	196	6	Demographics	demographic	NNS
cord-309556-xv3413k1	196	7	of	of	IN
cord-309556-xv3413k1	196	8	donors	donor	NNS
cord-309556-xv3413k1	196	9	for	for	IN
cord-309556-xv3413k1	196	10	GTEx	gtex	NN
cord-309556-xv3413k1	196	11	lung	lung	NN
cord-309556-xv3413k1	196	12	samples	sample	NNS
cord-309556-xv3413k1	196	13	.	.	.
cord-309556-xv3413k1	197	1	(	(	-LRB-
cord-309556-xv3413k1	197	2	Gordon	Gordon	NNP
cord-309556-xv3413k1	197	3	et	et	NNP
cord-309556-xv3413k1	197	4	al	al	NNP
cord-309556-xv3413k1	197	5	.	.	NNP
cord-309556-xv3413k1	197	6	,	,	,
cord-309556-xv3413k1	197	7	2020	2020	CD
cord-309556-xv3413k1	197	8	)	)	-RRB-
cord-309556-xv3413k1	197	9	with	with	IN
cord-309556-xv3413k1	197	10	age	age	NN
cord-309556-xv3413k1	197	11	-	-	HYPH
cord-309556-xv3413k1	197	12	association	association	NN
cord-309556-xv3413k1	197	13	statistics	statistic	NNS
cord-309556-xv3413k1	197	14	from	from	IN
cord-309556-xv3413k1	197	15	this	this	DT
cord-309556-xv3413k1	197	16	study	study	NN
cord-309556-xv3413k1	197	17	.	.	.
cord-309556-xv3413k1	198	1	Table	table	NN
cord-309556-xv3413k1	198	2	S22	S22	NNP
cord-309556-xv3413k1	198	3	:	:	:
cord-309556-xv3413k1	199	1	Differential	differential	JJ
cord-309556-xv3413k1	199	2	expression	expression	NN
cord-309556-xv3413k1	199	3	analysis	analysis	NN
cord-309556-xv3413k1	199	4	in	in	IN
cord-309556-xv3413k1	199	5	A549	a549	JJ
cord-309556-xv3413k1	199	6	cells	cell	NNS
cord-309556-xv3413k1	199	7	,	,	,
cord-309556-xv3413k1	199	8	infected	infect	VBN
cord-309556-xv3413k1	199	9	with	with	IN
cord-309556-xv3413k1	199	10	SARS	SARS	NNP
cord-309556-xv3413k1	199	11	-	-	HYPH
cord-309556-xv3413k1	199	12	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	199	13	vs	vs	IN
cord-309556-xv3413k1	199	14	mock	mock	JJ
cord-309556-xv3413k1	199	15	control	control	NN
cord-309556-xv3413k1	199	16	,	,	,
cord-309556-xv3413k1	199	17	with	with	IN
cord-309556-xv3413k1	199	18	age	age	NN
cord-309556-xv3413k1	199	19	-	-	HYPH
cord-309556-xv3413k1	199	20	association	association	NN
cord-309556-xv3413k1	199	21	annotations	annotation	NNS
cord-309556-xv3413k1	199	22	.	.	.
cord-309556-xv3413k1	200	1	Table	table	NN
cord-309556-xv3413k1	200	2	S23	s23	NN
cord-309556-xv3413k1	200	3	:	:	:
cord-309556-xv3413k1	200	4	Differential	differential	JJ
cord-309556-xv3413k1	200	5	expression	expression	NN
cord-309556-xv3413k1	200	6	analysis	analysis	NN
cord-309556-xv3413k1	200	7	in	in	IN
cord-309556-xv3413k1	200	8	A549-ACE2	A549-ACE2	NNP
cord-309556-xv3413k1	200	9	cells	cell	NNS
cord-309556-xv3413k1	200	10	,	,	,
cord-309556-xv3413k1	200	11	infected	infect	VBN
cord-309556-xv3413k1	200	12	with	with	IN
cord-309556-xv3413k1	200	13	SARS	SARS	NNP
cord-309556-xv3413k1	200	14	-	-	HYPH
cord-309556-xv3413k1	200	15	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	200	16	vs	vs	IN
cord-309556-xv3413k1	200	17	mock	mock	JJ
cord-309556-xv3413k1	200	18	control	control	NN
cord-309556-xv3413k1	200	19	,	,	,
cord-309556-xv3413k1	200	20	with	with	IN
cord-309556-xv3413k1	200	21	age	age	NN
cord-309556-xv3413k1	200	22	-	-	HYPH
cord-309556-xv3413k1	200	23	association	association	NN
cord-309556-xv3413k1	200	24	annotations	annotation	NNS
cord-309556-xv3413k1	200	25	.	.	.
cord-309556-xv3413k1	201	1	Table	table	NN
cord-309556-xv3413k1	201	2	S24	S24	NNP
cord-309556-xv3413k1	201	3	:	:	:
cord-309556-xv3413k1	201	4	Differential	differential	JJ
cord-309556-xv3413k1	201	5	expression	expression	NN
cord-309556-xv3413k1	201	6	analysis	analysis	NN
cord-309556-xv3413k1	201	7	in	in	IN
cord-309556-xv3413k1	201	8	Calu-3	Calu-3	NNP
cord-309556-xv3413k1	201	9	cells	cell	NNS
cord-309556-xv3413k1	201	10	,	,	,
cord-309556-xv3413k1	201	11	infected	infect	VBN
cord-309556-xv3413k1	201	12	with	with	IN
cord-309556-xv3413k1	201	13	SARS	SARS	NNP
cord-309556-xv3413k1	201	14	-	-	HYPH
cord-309556-xv3413k1	201	15	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	201	16	vs	vs	IN
cord-309556-xv3413k1	201	17	mock	mock	JJ
cord-309556-xv3413k1	201	18	control	control	NN
cord-309556-xv3413k1	201	19	,	,	,
cord-309556-xv3413k1	201	20	with	with	IN
cord-309556-xv3413k1	201	21	age	age	NN
cord-309556-xv3413k1	201	22	-	-	HYPH
cord-309556-xv3413k1	201	23	association	association	NN
cord-309556-xv3413k1	201	24	annotations	annotation	NNS
cord-309556-xv3413k1	201	25	.	.	.
cord-309556-xv3413k1	202	1	CDKN1B	CDKN1B	NNP
cord-309556-xv3413k1	202	2	 	 	_SP
cord-309556-xv3413k1	203	1	GNA13	gna13	IN
cord-309556-xv3413k1	203	2	 	 	_SP
cord-309556-xv3413k1	204	1	RAB8B	RAB8B	NNP
cord-309556-xv3413k1	204	2	 	 	_SP
cord-309556-xv3413k1	205	1	N4BP3	N4BP3	NNP
cord-309556-xv3413k1	205	2	 	 	_SP
cord-309556-xv3413k1	206	1	RASGRP1	RASGRP1	NNP
cord-309556-xv3413k1	206	2	 	 	_SP
cord-309556-xv3413k1	207	1	CAMSAP2	CAMSAP2	NNP
cord-309556-xv3413k1	207	2	 	 	_SP
cord-309556-xv3413k1	208	1	MXI1	MXI1	NNP
cord-309556-xv3413k1	208	2	 	 	_SP
cord-309556-xv3413k1	209	1	GEM	GEM	NNP
cord-309556-xv3413k1	209	2	 	 	_SP
cord-309556-xv3413k1	210	1	C1S	c1s	CC
cord-309556-xv3413k1	210	2	 	 	_SP
cord-309556-xv3413k1	211	1	RBM33	RBM33	NNP
cord-309556-xv3413k1	211	2	 	 	_SP
cord-309556-xv3413k1	212	1	RASA2	RASA2	NNP
cord-309556-xv3413k1	212	2	 	 	_SP
cord-309556-xv3413k1	213	1	BRWD1	BRWD1	NNP
cord-309556-xv3413k1	213	2	 	 	_SP
cord-309556-xv3413k1	214	1	PHC3	PHC3	NNP
cord-309556-xv3413k1	214	2	 	 	_SP
cord-309556-xv3413k1	215	1	GATAD2B	GATAD2B	NNP
cord-309556-xv3413k1	215	2	 	 	_SP
cord-309556-xv3413k1	216	1	PNRC1	PNRC1	NNP
cord-309556-xv3413k1	216	2	 	 	_SP
cord-309556-xv3413k1	217	1	ARID4B	ARID4B	NNP
cord-309556-xv3413k1	217	2	 	 	_SP
cord-309556-xv3413k1	218	1	ATRX	ATRX	NNP
cord-309556-xv3413k1	218	2	 	 	_SP
cord-309556-xv3413k1	219	1	CLK1	CLK1	NNP
cord-309556-xv3413k1	219	2	 	 	_SP
cord-309556-xv3413k1	220	1	PNISR	PNISR	NNP
cord-309556-xv3413k1	220	2	 	 	_SP
cord-309556-xv3413k1	221	1	PRTG	PRTG	NNP
cord-309556-xv3413k1	221	2	 	 	_SP
cord-309556-xv3413k1	222	1	H1F0	H1F0	NNP
cord-309556-xv3413k1	222	2	 	 	_SP
cord-309556-xv3413k1	223	1	NCKIPSD	NCKIPSD	NNP
cord-309556-xv3413k1	223	2	 	 	_SP
cord-309556-xv3413k1	224	1	CNN3	CNN3	NNP
cord-309556-xv3413k1	224	2	 	 	_SP
cord-309556-xv3413k1	224	3	PTOV1	PTOV1	NNP
cord-309556-xv3413k1	224	4	 	 	_SP
cord-309556-xv3413k1	225	1	CFD	CFD	NNP
cord-309556-xv3413k1	225	2	 	 	_SP
cord-309556-xv3413k1	225	3	RHOC	RHOC	NNP
cord-309556-xv3413k1	225	4	 	 	_SP
cord-309556-xv3413k1	226	1	POLR2F	POLR2F	NNP
cord-309556-xv3413k1	226	2	 	 	_SP
cord-309556-xv3413k1	227	1	GNAI2	GNAI2	NNP
cord-309556-xv3413k1	227	2	 	 	_SP
cord-309556-xv3413k1	228	1	TK1	tk1	JJ
cord-309556-xv3413k1	228	2	 	 	_SP
cord-309556-xv3413k1	229	1	TM4SF4	TM4SF4	NNP
cord-309556-xv3413k1	229	2	 	 	_SP
cord-309556-xv3413k1	230	1	PSKH1	PSKH1	NNP
cord-309556-xv3413k1	230	2	 	 	_SP
cord-309556-xv3413k1	231	1	AP1M2	AP1M2	NNP
cord-309556-xv3413k1	231	2	 	 	_SP
cord-309556-xv3413k1	232	1	MSH2	MSH2	NNP
cord-309556-xv3413k1	232	2	 	 	_SP
cord-309556-xv3413k1	233	1	ATP6V0E2	ATP6V0E2	NNP
cord-309556-xv3413k1	233	2	 	 	_SP
cord-309556-xv3413k1	234	1	PGAM5	PGAM5	NNP
cord-309556-xv3413k1	234	2	 	 	_SP
cord-309556-xv3413k1	235	1	MVK	MVK	NNP
cord-309556-xv3413k1	235	2	 	 	_SP
cord-309556-xv3413k1	236	1	AACS	AACS	NNP
cord-309556-xv3413k1	236	2	 	 	_SP
cord-309556-xv3413k1	237	1	ACACA	ACACA	NNP
cord-309556-xv3413k1	237	2	 	 	_SP
cord-309556-xv3413k1	238	1	ACSS2	ACSS2	NNP
cord-309556-xv3413k1	238	2	 	 	_SP
cord-309556-xv3413k1	239	1	NIPSNAP1	NIPSNAP1	NNP
cord-309556-xv3413k1	239	2	 	 	_SP
cord-309556-xv3413k1	240	1	NSDHL	NSDHL	NNP
cord-309556-xv3413k1	240	2	 	 	_SP
cord-309556-xv3413k1	241	1	AIFM1	aifm1	NN
cord-309556-xv3413k1	241	2	 	 	_SP
cord-309556-xv3413k1	242	1	AGR2	AGR2	NNP
cord-309556-xv3413k1	242	2	 	 	_SP
cord-309556-xv3413k1	243	1	GIPC1	GIPC1	NNP
cord-309556-xv3413k1	243	2	 	 	_SP
cord-309556-xv3413k1	244	1	MMAB	MMAB	NNP
cord-309556-xv3413k1	244	2	 	 	_SP
cord-309556-xv3413k1	245	1	HADH	HADH	NNP
cord-309556-xv3413k1	245	2	 	 	_SP
cord-309556-xv3413k1	245	3	QDPR	QDPR	NNP
cord-309556-xv3413k1	245	4	 	 	_SP
cord-309556-xv3413k1	246	1	AP1S1	AP1S1	NNP
cord-309556-xv3413k1	246	2	 	 	_SP
cord-309556-xv3413k1	247	1	NDUFA7	NDUFA7	NNP
cord-309556-xv3413k1	247	2	 	 	_SP
cord-309556-xv3413k1	248	1	POLDIP2	POLDIP2	NNP
cord-309556-xv3413k1	248	2	 	 	_SP
cord-309556-xv3413k1	249	1	AHCY	AHCY	NNP
cord-309556-xv3413k1	249	2	 	 	_SP
cord-309556-xv3413k1	250	1	MRPS28	MRPS28	NNS
cord-309556-xv3413k1	250	2	 	 	_SP
cord-309556-xv3413k1	251	1	SAMM50	samm50	XX
cord-309556-xv3413k1	251	2	 	 	_SP
cord-309556-xv3413k1	252	1	PRPF19	PRPF19	VBN
cord-309556-xv3413k1	252	2	 	 	_SP
cord-309556-xv3413k1	253	1	NUP93	NUP93	NNP
cord-309556-xv3413k1	253	2	 	 	_SP
cord-309556-xv3413k1	254	1	GBA	GBA	NNP
cord-309556-xv3413k1	254	2	 	 	_SP
cord-309556-xv3413k1	255	1	CLN3	CLN3	NNP
cord-309556-xv3413k1	255	2	 	 	_SP
cord-309556-xv3413k1	255	3	APEH	APEH	NNP
cord-309556-xv3413k1	255	4	 	 	_SP
cord-309556-xv3413k1	256	1	ATIC	ATIC	NNP
cord-309556-xv3413k1	256	2	 	 	_SP
cord-309556-xv3413k1	257	1	ARPC1B	ARPC1B	NNP
cord-309556-xv3413k1	257	2	 	 	_SP
cord-309556-xv3413k1	258	1	PPP1CA	PPP1CA	NNP
cord-309556-xv3413k1	258	2	 	 	_SP
cord-309556-xv3413k1	259	1	APRT	APRT	NNP
cord-309556-xv3413k1	259	2	 	 	_SP
cord-309556-xv3413k1	260	1	ATP6V0D1	ATP6V0D1	NNP
cord-309556-xv3413k1	260	2	 	 	_SP
cord-309556-xv3413k1	261	1	AKR1A1	AKR1A1	NNP
cord-309556-xv3413k1	261	2	 	 	_SP
cord-309556-xv3413k1	262	1	PHB	PHB	NNP
cord-309556-xv3413k1	262	2	 	 	_SP
cord-309556-xv3413k1	263	1	C1QBP	C1QBP	NNP
cord-309556-xv3413k1	263	2	 	 	_SP
cord-309556-xv3413k1	264	1	PARP1	PARP1	NNP
cord-309556-xv3413k1	264	2	 	 	_SP
cord-309556-xv3413k1	265	1	CBR1	CBR1	NNP
cord-309556-xv3413k1	265	2	 	 	_SP
cord-309556-xv3413k1	266	1	ACAT1	ACAT1	NNP
cord-309556-xv3413k1	266	2	 	 	_SP
cord-309556-xv3413k1	267	1	PDHB	PDHB	NNP
cord-309556-xv3413k1	267	2	 	 	_SP
cord-309556-xv3413k1	268	1	NDUFA9	NDUFA9	NNP
cord-309556-xv3413k1	268	2	 	 	_SP
cord-309556-xv3413k1	269	1	MRPL27	MRPL27	NNP
cord-309556-xv3413k1	269	2	 	 	_SP
cord-309556-xv3413k1	270	1	PRDX3	PRDX3	NNP
cord-309556-xv3413k1	270	2	 	 	_SP
cord-309556-xv3413k1	271	1	MTCH2	MTCH2	NNP
cord-309556-xv3413k1	271	2	 	 	_SP
cord-309556-xv3413k1	271	3	ORMDL2	ormdl2	XX
cord-309556-xv3413k1	271	4	 	 	_SP
cord-309556-xv3413k1	272	1	NDUFS3	NDUFS3	NNP
cord-309556-xv3413k1	272	2	 	 	_SP
cord-309556-xv3413k1	273	1	A	a	DT
cord-309556-xv3413k1	273	2	T	t	NN
cord-309556-xv3413k1	273	3	P	p	NN
cord-309556-xv3413k1	273	4	1	1	CD
cord-309556-xv3413k1	273	5	B	b	NN
cord-309556-xv3413k1	273	6	1	1	CD
cord-309556-xv3413k1	273	7	A	a	NN
cord-309556-xv3413k1	273	8	L	l	NN
cord-309556-xv3413k1	273	9	G	g	NN
cord-309556-xv3413k1	274	1	5	5	CD
cord-309556-xv3413k1	274	2	N	n	NN
cord-309556-xv3413k1	274	3	E	e	NN
cord-309556-xv3413k1	274	4	U	u	NN
cord-309556-xv3413k1	274	5	1	1	CD
cord-309556-xv3413k1	275	1	P	p	NN
cord-309556-xv3413k1	275	2	R	r	NN
cord-309556-xv3413k1	276	1	I	-PRON-	PRP
cord-309556-xv3413k1	277	1	M	M	NNP
cord-309556-xv3413k1	277	2	1	1	CD
cord-309556-xv3413k1	278	1	C	C	NNP
cord-309556-xv3413k1	279	1	E	e	NN
cord-309556-xv3413k1	279	2	N	n	NN
cord-309556-xv3413k1	280	1	P	p	NN
cord-309556-xv3413k1	280	2	F	f	NN
cord-309556-xv3413k1	280	3	H	h	NN
cord-309556-xv3413k1	280	4	O	o	NN
cord-309556-xv3413k1	281	1	O	o	UH
cord-309556-xv3413k1	281	2	K	k	NN
cord-309556-xv3413k1	281	3	1	1	CD
cord-309556-xv3413k1	281	4	G	g	NN
cord-309556-xv3413k1	281	5	C	c	NN
cord-309556-xv3413k1	281	6	C	c	NN
cord-309556-xv3413k1	281	7	1	1	CD
cord-309556-xv3413k1	281	8	P	p	NN
cord-309556-xv3413k1	282	1	I	-PRON-	PRP
cord-309556-xv3413k1	283	1	G	g	NN
cord-309556-xv3413k1	283	2	O	o	NN
cord-309556-xv3413k1	283	3	N	n	NN
cord-309556-xv3413k1	283	4	A	a	NN
cord-309556-xv3413k1	284	1	R	R	NNP
cord-309556-xv3413k1	284	2	S	s	NN
cord-309556-xv3413k1	285	1	2	2	LS
cord-309556-xv3413k1	285	2	A	a	NN
cord-309556-xv3413k1	285	3	A	a	NN
cord-309556-xv3413k1	285	4	R	r	NN
cord-309556-xv3413k1	285	5	2	2	CD
cord-309556-xv3413k1	285	6	A	a	NN
cord-309556-xv3413k1	285	7	T	t	NN
cord-309556-xv3413k1	285	8	P	p	NN
cord-309556-xv3413k1	285	9	6	6	CD
cord-309556-xv3413k1	285	10	V	v	NN
cord-309556-xv3413k1	285	11	1	1	CD
cord-309556-xv3413k1	286	1	A	a	DT
cord-309556-xv3413k1	286	2	N	n	NN
cord-309556-xv3413k1	286	3	D	d	NN
cord-309556-xv3413k1	286	4	U	u	NN
cord-309556-xv3413k1	286	5	F	f	NN
cord-309556-xv3413k1	286	6	A	a	DT
cord-309556-xv3413k1	286	7	F	f	NN
cord-309556-xv3413k1	287	1	1	1	LS
cord-309556-xv3413k1	287	2	A	a	CD
cord-309556-xv3413k1	288	1	G	g	NN
cord-309556-xv3413k1	289	1	P	p	NN
cord-309556-xv3413k1	289	2	S	s	NN
cord-309556-xv3413k1	290	1	N	N	NNP
cord-309556-xv3413k1	291	1	P	p	NN
cord-309556-xv3413k1	291	2	C	c	NN
cord-309556-xv3413k1	291	3	2	2	CD
cord-309556-xv3413k1	291	4	P	p	NN
cord-309556-xv3413k1	291	5	P	p	NN
cord-309556-xv3413k1	291	6	T	t	NN
cord-309556-xv3413k1	291	7	1	1	CD
cord-309556-xv3413k1	291	8	N	n	NN
cord-309556-xv3413k1	291	9	D	d	NN
cord-309556-xv3413k1	291	10	U	u	NN
cord-309556-xv3413k1	291	11	F	f	NN
cord-309556-xv3413k1	291	12	B	b	NN
cord-309556-xv3413k1	291	13	9	9	CD
cord-309556-xv3413k1	291	14	-log	-log	SYM
cord-309556-xv3413k1	291	15	10	10	CD
cord-309556-xv3413k1	291	16	(	(	-LRB-
cord-309556-xv3413k1	291	17	adj	adj	JJ
cord-309556-xv3413k1	291	18	.	.	.
cord-309556-xv3413k1	292	1	p	p	NN
cord-309556-xv3413k1	292	2	-	-	HYPH
cord-309556-xv3413k1	292	3	value	value	NN
cord-309556-xv3413k1	292	4	)	)	-RRB-
cord-309556-xv3413k1	293	1	GEM	GEM	NNP
cord-309556-xv3413k1	293	2	 	 	_SP
cord-309556-xv3413k1	294	1	C1S	c1s	CC
cord-309556-xv3413k1	294	2	 	 	_SP
cord-309556-xv3413k1	295	1	GNA13	gna13	IN
cord-309556-xv3413k1	295	2	 	 	_SP
cord-309556-xv3413k1	296	1	RAB8B	RAB8B	NNP
cord-309556-xv3413k1	296	2	 	 	_SP
cord-309556-xv3413k1	297	1	BRWD1	BRWD1	NNP
cord-309556-xv3413k1	297	2	 	 	_SP
cord-309556-xv3413k1	298	1	CNOT6L	CNOT6L	NNP
cord-309556-xv3413k1	298	2	 	 	_SP
cord-309556-xv3413k1	299	1	CDKN1B	CDKN1B	NNP
cord-309556-xv3413k1	299	2	 	 	_SP
cord-309556-xv3413k1	300	1	CAMSAP2	CAMSAP2	NNP
cord-309556-xv3413k1	300	2	 	 	_SP
cord-309556-xv3413k1	301	1	MXI1	MXI1	NNP
cord-309556-xv3413k1	301	2	 	 	_SP
cord-309556-xv3413k1	302	1	RASA2	RASA2	NNP
cord-309556-xv3413k1	302	2	 	 	_SP
cord-309556-xv3413k1	303	1	RBM33	RBM33	NNP
cord-309556-xv3413k1	303	2	 	 	_SP
cord-309556-xv3413k1	304	1	GATAD2B	GATAD2B	NNP
cord-309556-xv3413k1	304	2	 	 	_SP
cord-309556-xv3413k1	305	1	PHC3	PHC3	NNP
cord-309556-xv3413k1	305	2	 	 	_SP
cord-309556-xv3413k1	306	1	CLK1	CLK1	NNP
cord-309556-xv3413k1	306	2	 	 	_SP
cord-309556-xv3413k1	307	1	ARID4B	ARID4B	NNP
cord-309556-xv3413k1	307	2	 	 	_SP
cord-309556-xv3413k1	308	1	ATRX	ATRX	NNP
cord-309556-xv3413k1	308	2	 	 	_SP
cord-309556-xv3413k1	309	1	PNISR	PNISR	NNP
cord-309556-xv3413k1	309	2	 	 	_SP
cord-309556-xv3413k1	310	1	PNRC1	PNRC1	NNP
cord-309556-xv3413k1	310	2	 	 	_SP
cord-309556-xv3413k1	311	1	PRTG	PRTG	NNP
cord-309556-xv3413k1	311	2	 	 	_SP
cord-309556-xv3413k1	312	1	H1F0	H1F0	NNP
cord-309556-xv3413k1	312	2	 	 	_SP
cord-309556-xv3413k1	313	1	NCKIPSD	NCKIPSD	NNP
cord-309556-xv3413k1	313	2	 	 	_SP
cord-309556-xv3413k1	314	1	CNN3	CNN3	NNP
cord-309556-xv3413k1	314	2	 	 	_SP
cord-309556-xv3413k1	315	1	GNAI2	GNAI2	NNP
cord-309556-xv3413k1	315	2	 	 	_SP
cord-309556-xv3413k1	316	1	RHOC	RHOC	NNP
cord-309556-xv3413k1	316	2	 	 	_SP
cord-309556-xv3413k1	317	1	CFD	CFD	NNP
cord-309556-xv3413k1	317	2	 	 	_SP
cord-309556-xv3413k1	318	1	PTOV1	PTOV1	NNP
cord-309556-xv3413k1	318	2	 	 	_SP
cord-309556-xv3413k1	319	1	POLR2F	POLR2F	NNP
cord-309556-xv3413k1	319	2	 	 	_SP
cord-309556-xv3413k1	320	1	AP1M2	AP1M2	NNP
cord-309556-xv3413k1	320	2	 	 	_SP
cord-309556-xv3413k1	321	1	AGR2	AGR2	NNP
cord-309556-xv3413k1	321	2	 	 	_SP
cord-309556-xv3413k1	322	1	TK1	tk1	JJ
cord-309556-xv3413k1	322	2	 	 	_SP
cord-309556-xv3413k1	322	3	TM4SF4	TM4SF4	NNP
cord-309556-xv3413k1	322	4	 	 	_SP
cord-309556-xv3413k1	322	5	GBA	GBA	NNP
cord-309556-xv3413k1	322	6	 	 	_SP
cord-309556-xv3413k1	323	1	PGAM5	PGAM5	NNP
cord-309556-xv3413k1	323	2	 	 	_SP
cord-309556-xv3413k1	324	1	PSKH1	PSKH1	NNP
cord-309556-xv3413k1	324	2	 	 	_SP
cord-309556-xv3413k1	325	1	ACSS2	ACSS2	NNP
cord-309556-xv3413k1	325	2	 	 	_SP
cord-309556-xv3413k1	326	1	ACACA	ACACA	NNP
cord-309556-xv3413k1	326	2	 	 	_SP
cord-309556-xv3413k1	327	1	AACS	AACS	NNP
cord-309556-xv3413k1	327	2	 	 	_SP
cord-309556-xv3413k1	328	1	MVK	MVK	NNP
cord-309556-xv3413k1	328	2	 	 	_SP
cord-309556-xv3413k1	329	1	MSH2	MSH2	NNP
cord-309556-xv3413k1	329	2	 	 	_SP
cord-309556-xv3413k1	330	1	ATP6V0E2	ATP6V0E2	NNP
cord-309556-xv3413k1	330	2	 	 	_SP
cord-309556-xv3413k1	331	1	NUP93	NUP93	NNP
cord-309556-xv3413k1	331	2	 	 	_SP
cord-309556-xv3413k1	332	1	NIPSNAP1	NIPSNAP1	NNP
cord-309556-xv3413k1	332	2	 	 	_SP
cord-309556-xv3413k1	333	1	NSDHL	NSDHL	NNP
cord-309556-xv3413k1	333	2	 	 	_SP
cord-309556-xv3413k1	334	1	AIFM1	aifm1	NN
cord-309556-xv3413k1	334	2	 	 	_SP
cord-309556-xv3413k1	335	1	ACAT1	ACAT1	NNP
cord-309556-xv3413k1	335	2	 	 	_SP
cord-309556-xv3413k1	336	1	CBR1	CBR1	NNP
cord-309556-xv3413k1	336	2	 	 	_SP
cord-309556-xv3413k1	337	1	GIPC1	GIPC1	NNP
cord-309556-xv3413k1	337	2	 	 	_SP
cord-309556-xv3413k1	338	1	MMAB	MMAB	NNP
cord-309556-xv3413k1	338	2	 	 	_SP
cord-309556-xv3413k1	339	1	HADH	HADH	NNP
cord-309556-xv3413k1	339	2	 	 	_SP
cord-309556-xv3413k1	340	1	MRPS28	MRPS28	NNS
cord-309556-xv3413k1	340	2	 	 	_SP
cord-309556-xv3413k1	341	1	AP1S1	AP1S1	NNP
cord-309556-xv3413k1	341	2	 	 	_SP
cord-309556-xv3413k1	342	1	POLDIP2	POLDIP2	NNP
cord-309556-xv3413k1	342	2	 	 	_SP
cord-309556-xv3413k1	342	3	QDPR	QDPR	NNP
cord-309556-xv3413k1	342	4	 	 	_SP
cord-309556-xv3413k1	343	1	AHCY	AHCY	NNP
cord-309556-xv3413k1	343	2	 	 	_SP
cord-309556-xv3413k1	343	3	ATIC	ATIC	NNP
cord-309556-xv3413k1	343	4	 	 	_SP
cord-309556-xv3413k1	343	5	APEH	APEH	NNP
cord-309556-xv3413k1	343	6	 	 	_SP
cord-309556-xv3413k1	344	1	CLN3	CLN3	NNP
cord-309556-xv3413k1	344	2	 	 	_SP
cord-309556-xv3413k1	345	1	PRPF19	PRPF19	VBN
cord-309556-xv3413k1	345	2	 	 	_SP
cord-309556-xv3413k1	346	1	SAMM50	samm50	XX
cord-309556-xv3413k1	346	2	 	 	_SP
cord-309556-xv3413k1	347	1	ARPC1B	ARPC1B	NNP
cord-309556-xv3413k1	347	2	 	 	_SP
cord-309556-xv3413k1	348	1	PPP1CA	PPP1CA	NNP
cord-309556-xv3413k1	348	2	 	 	_SP
cord-309556-xv3413k1	349	1	APRT	APRT	NNP
cord-309556-xv3413k1	349	2	 	 	_SP
cord-309556-xv3413k1	350	1	PARP1	PARP1	NNP
cord-309556-xv3413k1	350	2	 	 	_SP
cord-309556-xv3413k1	351	1	PDHB	PDHB	NNP
cord-309556-xv3413k1	351	2	 	 	_SP
cord-309556-xv3413k1	352	1	MTCH2	MTCH2	NNP
cord-309556-xv3413k1	352	2	 	 	_SP
cord-309556-xv3413k1	353	1	NDUFA9	NDUFA9	NNP
cord-309556-xv3413k1	353	2	 	 	_SP
cord-309556-xv3413k1	354	1	MRPL27	MRPL27	NNP
cord-309556-xv3413k1	354	2	 	 	_SP
cord-309556-xv3413k1	355	1	ASNA1	ASNA1	NNP
cord-309556-xv3413k1	355	2	 	 	_SP
cord-309556-xv3413k1	356	1	NDUFS3	NDUFS3	NNP
cord-309556-xv3413k1	356	2	 	 	_SP
cord-309556-xv3413k1	357	1	C1QBP	C1QBP	NNP
cord-309556-xv3413k1	357	2	 	 	_SP
cord-309556-xv3413k1	358	1	NDUFA7	NDUFA7	NNP
cord-309556-xv3413k1	358	2	 	 	_SP
cord-309556-xv3413k1	359	1	PHB	PHB	NNP
cord-309556-xv3413k1	359	2	 	 	_SP
cord-309556-xv3413k1	359	3	ORMDL2	ormdl2	XX
cord-309556-xv3413k1	359	4	 	 	_SP
cord-309556-xv3413k1	360	1	ATP6V0D1	ATP6V0D1	NNP
cord-309556-xv3413k1	360	2	 	 	_SP
cord-309556-xv3413k1	361	1	AKR1A1	AKR1A1	NNP
cord-309556-xv3413k1	361	2	 	 	_SP
cord-309556-xv3413k1	361	3	PRDX3	PRDX3	NNP
cord-309556-xv3413k1	361	4	 	 	_SP
cord-309556-xv3413k1	361	5	Estimating	estimate	VBG
cord-309556-xv3413k1	361	6	clinical	clinical	JJ
cord-309556-xv3413k1	361	7	severity	severity	NN
cord-309556-xv3413k1	361	8	of	of	IN
cord-309556-xv3413k1	361	9	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	361	10	from	from	IN
cord-309556-xv3413k1	361	11	the	the	DT
cord-309556-xv3413k1	361	12	transmission	transmission	NN
cord-309556-xv3413k1	361	13	dynamics	dynamic	NNS
cord-309556-xv3413k1	361	14	in	in	IN
cord-309556-xv3413k1	361	15	Wuhan	Wuhan	NNP
cord-309556-xv3413k1	361	16	,	,	,
cord-309556-xv3413k1	361	17	China	China	NNP
cord-309556-xv3413k1	361	18	Adjusted	adjust	VBD
cord-309556-xv3413k1	361	19	age	age	NN
cord-309556-xv3413k1	361	20	-	-	HYPH
cord-309556-xv3413k1	361	21	specific	specific	JJ
cord-309556-xv3413k1	361	22	case	case	NN
cord-309556-xv3413k1	361	23	fatality	fatality	NN
cord-309556-xv3413k1	361	24	ratio	ratio	NN
cord-309556-xv3413k1	361	25	during	during	IN
cord-309556-xv3413k1	361	26	the	the	DT
cord-309556-xv3413k1	361	27	COVID-19	covid-19	JJ
cord-309556-xv3413k1	361	28	epidemic	epidemic	NN
cord-309556-xv3413k1	361	29	in	in	IN
cord-309556-xv3413k1	361	30	Hubei	Hubei	NNP
cord-309556-xv3413k1	361	31	,	,	,
cord-309556-xv3413k1	361	32	China	China	NNP
cord-309556-xv3413k1	361	33	Case	Case	NNP
cord-309556-xv3413k1	361	34	-	-	HYPH
cord-309556-xv3413k1	361	35	Fatality	Fatality	NNP
cord-309556-xv3413k1	361	36	Rate	Rate	NNP
cord-309556-xv3413k1	361	37	and	and	CC
cord-309556-xv3413k1	361	38	Characteristics	characteristic	NNS
cord-309556-xv3413k1	361	39	of	of	IN
cord-309556-xv3413k1	361	40	Patients	patient	NNS
cord-309556-xv3413k1	361	41	Dying	die	VBG
cord-309556-xv3413k1	361	42	in	in	IN
cord-309556-xv3413k1	361	43	Relation	Relation	NNP
cord-309556-xv3413k1	361	44	to	to	TO
cord-309556-xv3413k1	361	45	COVID-19	covid-19	VB
cord-309556-xv3413k1	361	46	in	in	IN
cord-309556-xv3413k1	361	47	Italy	Italy	NNP
cord-309556-xv3413k1	361	48	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	361	49	Disease	Disease	NNP
cord-309556-xv3413k1	361	50	2019	2019	CD
cord-309556-xv3413k1	362	1	(	(	-LRB-
cord-309556-xv3413k1	362	2	COVID-19	covid-19	VB
cord-309556-xv3413k1	362	3	)	)	-RRB-
cord-309556-xv3413k1	362	4	in	in	IN
cord-309556-xv3413k1	362	5	Italy	Italy	NNP
cord-309556-xv3413k1	362	6	Severe	Severe	NNP
cord-309556-xv3413k1	362	7	Outcomes	Outcomes	NNPS
cord-309556-xv3413k1	363	1	Among	among	IN
cord-309556-xv3413k1	363	2	Patients	patient	NNS
cord-309556-xv3413k1	363	3	with	with	IN
cord-309556-xv3413k1	363	4	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	363	5	Disease	Disease	NNP
cord-309556-xv3413k1	363	6	2019	2019	CD
cord-309556-xv3413k1	364	1	(	(	-LRB-
cord-309556-xv3413k1	364	2	COVID-19	covid-19	VB
cord-309556-xv3413k1	364	3	)	)	-RRB-
cord-309556-xv3413k1	364	4	-United	-unite	VBD
cord-309556-xv3413k1	364	5	States	States	NNP
cord-309556-xv3413k1	364	6	A	A	NNP
cord-309556-xv3413k1	364	7	Novel	Novel	NNP
cord-309556-xv3413k1	364	8	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	364	9	from	from	IN
cord-309556-xv3413k1	364	10	Patients	patient	NNS
cord-309556-xv3413k1	364	11	with	with	IN
cord-309556-xv3413k1	364	12	Pneumonia	Pneumonia	NNP
cord-309556-xv3413k1	364	13	in	in	IN
cord-309556-xv3413k1	364	14	China	China	NNP
cord-309556-xv3413k1	364	15	Genomic	Genomic	NNP
cord-309556-xv3413k1	364	16	characterisation	characterisation	NN
cord-309556-xv3413k1	364	17	and	and	CC
cord-309556-xv3413k1	364	18	epidemiology	epidemiology	NN
cord-309556-xv3413k1	364	19	of	of	IN
cord-309556-xv3413k1	364	20	2019	2019	CD
cord-309556-xv3413k1	364	21	novel	novel	JJ
cord-309556-xv3413k1	364	22	coronavirus	coronavirus	NN
cord-309556-xv3413k1	364	23	:	:	:
cord-309556-xv3413k1	364	24	implications	implication	NNS
cord-309556-xv3413k1	364	25	for	for	IN
cord-309556-xv3413k1	364	26	virus	virus	NN
cord-309556-xv3413k1	364	27	origins	origin	NNS
cord-309556-xv3413k1	364	28	and	and	CC
cord-309556-xv3413k1	364	29	receptor	receptor	NN
cord-309556-xv3413k1	364	30	binding	bind	VBG
cord-309556-xv3413k1	364	31	A	a	DT
cord-309556-xv3413k1	364	32	pneumonia	pneumonia	NN
cord-309556-xv3413k1	364	33	outbreak	outbreak	NN
cord-309556-xv3413k1	364	34	associated	associate	VBN
cord-309556-xv3413k1	364	35	with	with	IN
cord-309556-xv3413k1	364	36	a	a	DT
cord-309556-xv3413k1	364	37	new	new	JJ
cord-309556-xv3413k1	364	38	coronavirus	coronavirus	NN
cord-309556-xv3413k1	364	39	of	of	IN
cord-309556-xv3413k1	364	40	probable	probable	JJ
cord-309556-xv3413k1	364	41	bat	bat	NN
cord-309556-xv3413k1	364	42	origin	origin	NN
cord-309556-xv3413k1	364	43	Epidemiological	epidemiological	JJ
cord-309556-xv3413k1	364	44	Characteristics	characteristic	NNS
cord-309556-xv3413k1	364	45	of	of	IN
cord-309556-xv3413k1	364	46	2143	2143	CD
cord-309556-xv3413k1	364	47	Pediatric	Pediatric	NNP
cord-309556-xv3413k1	364	48	Patients	Patients	NNPS
cord-309556-xv3413k1	364	49	With	with	IN
cord-309556-xv3413k1	364	50	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	364	51	Disease	Disease	NNP
cord-309556-xv3413k1	364	52	in	in	IN
cord-309556-xv3413k1	364	53	China	China	NNP
cord-309556-xv3413k1	365	1	The	the	DT
cord-309556-xv3413k1	365	2	Genotype	Genotype	NNP
cord-309556-xv3413k1	365	3	-	-	HYPH
cord-309556-xv3413k1	365	4	Tissue	Tissue	NNP
cord-309556-xv3413k1	365	5	Expression	expression	NN
cord-309556-xv3413k1	365	6	(	(	-LRB-
cord-309556-xv3413k1	365	7	GTEx	gtex	NN
cord-309556-xv3413k1	365	8	)	)	-RRB-
cord-309556-xv3413k1	365	9	project	project	VB
cord-309556-xv3413k1	365	10	A	a	DT
cord-309556-xv3413k1	365	11	Novel	Novel	NNP
cord-309556-xv3413k1	365	12	Approach	Approach	NNP
cord-309556-xv3413k1	365	13	to	to	IN
cord-309556-xv3413k1	365	14	High	High	NNP
cord-309556-xv3413k1	365	15	-	-	HYPH
cord-309556-xv3413k1	365	16	Quality	Quality	NNP
cord-309556-xv3413k1	365	17	Postmortem	Postmortem	NNP
cord-309556-xv3413k1	365	18	Tissue	Tissue	NNP
cord-309556-xv3413k1	365	19	Procurement	procurement	NN
cord-309556-xv3413k1	365	20	:	:	:
cord-309556-xv3413k1	366	1	The	the	DT
cord-309556-xv3413k1	366	2	GTEx	gtex	NN
cord-309556-xv3413k1	366	3	Project	Project	NNP
cord-309556-xv3413k1	366	4	Cryo	Cryo	NNP
cord-309556-xv3413k1	366	5	-	-	HYPH
cord-309556-xv3413k1	366	6	EM	EM	NNP
cord-309556-xv3413k1	366	7	structure	structure	NN
cord-309556-xv3413k1	366	8	of	of	IN
cord-309556-xv3413k1	366	9	the	the	DT
cord-309556-xv3413k1	366	10	2019-nCoV	2019-ncov	CD
cord-309556-xv3413k1	366	11	spike	spike	NN
cord-309556-xv3413k1	366	12	in	in	IN
cord-309556-xv3413k1	366	13	the	the	DT
cord-309556-xv3413k1	366	14	prefusion	prefusion	NN
cord-309556-xv3413k1	366	15	conformation	conformation	NN
cord-309556-xv3413k1	366	16	Receptor	Receptor	NNP
cord-309556-xv3413k1	366	17	Recognition	Recognition	NNP
cord-309556-xv3413k1	366	18	by	by	IN
cord-309556-xv3413k1	366	19	the	the	DT
cord-309556-xv3413k1	366	20	Novel	Novel	NNP
cord-309556-xv3413k1	366	21	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	366	22	from	from	IN
cord-309556-xv3413k1	366	23	Wuhan	Wuhan	NNP
cord-309556-xv3413k1	366	24	:	:	:
cord-309556-xv3413k1	366	25	an	an	DT
cord-309556-xv3413k1	366	26	Analysis	Analysis	NNP
cord-309556-xv3413k1	366	27	Based	base	VBN
cord-309556-xv3413k1	366	28	on	on	IN
cord-309556-xv3413k1	366	29	Decade	decade	NN
cord-309556-xv3413k1	366	30	-	-	HYPH
cord-309556-xv3413k1	366	31	Long	Long	NNP
cord-309556-xv3413k1	366	32	Structural	Structural	NNP
cord-309556-xv3413k1	366	33	Studies	Studies	NNPS
cord-309556-xv3413k1	366	34	of	of	IN
cord-309556-xv3413k1	366	35	SARS	SARS	NNP
cord-309556-xv3413k1	366	36	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	366	37	SARS	SARS	NNP
cord-309556-xv3413k1	366	38	-	-	HYPH
cord-309556-xv3413k1	366	39	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	366	40	Cell	Cell	NNP
cord-309556-xv3413k1	366	41	Entry	entry	NN
cord-309556-xv3413k1	366	42	Depends	depend	VBZ
cord-309556-xv3413k1	366	43	on	on	IN
cord-309556-xv3413k1	366	44	ACE2	ACE2	NNP
cord-309556-xv3413k1	366	45	and	and	CC
cord-309556-xv3413k1	366	46	TMPRSS2	TMPRSS2	NNP
cord-309556-xv3413k1	366	47	and	and	CC
cord-309556-xv3413k1	366	48	Is	be	VBZ
cord-309556-xv3413k1	366	49	Blocked	block	VBN
cord-309556-xv3413k1	366	50	by	by	IN
cord-309556-xv3413k1	366	51	a	a	DT
cord-309556-xv3413k1	366	52	Clinically	clinically	RB
cord-309556-xv3413k1	366	53	Proven	Proven	NNP
cord-309556-xv3413k1	366	54	Protease	Protease	NNP
cord-309556-xv3413k1	366	55	Inhibitor	Inhibitor	NNP
cord-309556-xv3413k1	366	56	Structure	Structure	NNP
cord-309556-xv3413k1	366	57	,	,	,
cord-309556-xv3413k1	366	58	Function	Function	NNP
cord-309556-xv3413k1	366	59	,	,	,
cord-309556-xv3413k1	366	60	and	and	CC
cord-309556-xv3413k1	366	61	Antigenicity	Antigenicity	NNP
cord-309556-xv3413k1	366	62	of	of	IN
cord-309556-xv3413k1	366	63	the	the	DT
cord-309556-xv3413k1	366	64	SARS	SARS	NNP
cord-309556-xv3413k1	366	65	-	-	HYPH
cord-309556-xv3413k1	366	66	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	366	67	Spike	Spike	NNP
cord-309556-xv3413k1	366	68	Glycoprotein	Glycoprotein	NNP
cord-309556-xv3413k1	366	69	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	366	70	and	and	CC
cord-309556-xv3413k1	366	71	Italy	Italy	NNP
cord-309556-xv3413k1	366	72	:	:	:
cord-309556-xv3413k1	366	73	what	what	WP
cord-309556-xv3413k1	366	74	next	next	JJ
cord-309556-xv3413k1	366	75	?	?	.
cord-309556-xv3413k1	367	1	The	the	DT
cord-309556-xv3413k1	367	2	Lancet	Lancet	NNP
cord-309556-xv3413k1	367	3	0	0	CD
cord-309556-xv3413k1	367	4	Risk	risk	NN
cord-309556-xv3413k1	367	5	Factors	factor	NNS
cord-309556-xv3413k1	367	6	Associated	associate	VBN
cord-309556-xv3413k1	367	7	With	with	IN
cord-309556-xv3413k1	367	8	Acute	acute	JJ
cord-309556-xv3413k1	367	9	Respiratory	respiratory	JJ
cord-309556-xv3413k1	367	10	Distress	Distress	NNP
cord-309556-xv3413k1	367	11	Syndrome	Syndrome	NNP
cord-309556-xv3413k1	367	12	and	and	CC
cord-309556-xv3413k1	367	13	Death	death	NN
cord-309556-xv3413k1	367	14	in	in	IN
cord-309556-xv3413k1	367	15	Patients	Patients	NNP
cord-309556-xv3413k1	367	16	With	with	IN
cord-309556-xv3413k1	367	17	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	367	18	Disease	Disease	NNP
cord-309556-xv3413k1	368	1	The	the	DT
cord-309556-xv3413k1	368	2	Epidemiological	Epidemiological	NNP
cord-309556-xv3413k1	368	3	Characteristics	Characteristics	NNPS
cord-309556-xv3413k1	368	4	of	of	IN
cord-309556-xv3413k1	368	5	an	an	DT
cord-309556-xv3413k1	368	6	Outbreak	outbreak	NN
cord-309556-xv3413k1	368	7	of	of	IN
cord-309556-xv3413k1	368	8	2019	2019	CD
cord-309556-xv3413k1	368	9	Novel	Novel	NNP
cord-309556-xv3413k1	368	10	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	368	11	Diseases	Diseases	NNPS
cord-309556-xv3413k1	368	12	(	(	-LRB-
cord-309556-xv3413k1	368	13	COVID-19	COVID-19	NNP
cord-309556-xv3413k1	368	14	)	)	-RRB-
cord-309556-xv3413k1	368	15	-China	-China	.
cord-309556-xv3413k1	368	16	scRNA	scRNA	JJS
cord-309556-xv3413k1	368	17	-	-	HYPH
cord-309556-xv3413k1	368	18	seq	seq	NN
cord-309556-xv3413k1	368	19	assessment	assessment	NN
cord-309556-xv3413k1	368	20	of	of	IN
cord-309556-xv3413k1	368	21	the	the	DT
cord-309556-xv3413k1	368	22	human	human	JJ
cord-309556-xv3413k1	368	23	lung	lung	NN
cord-309556-xv3413k1	368	24	,	,	,
cord-309556-xv3413k1	368	25	spleen	spleen	NNS
cord-309556-xv3413k1	368	26	,	,	,
cord-309556-xv3413k1	368	27	and	and	CC
cord-309556-xv3413k1	368	28	esophagus	esophagus	NN
cord-309556-xv3413k1	368	29	tissue	tissue	NN
cord-309556-xv3413k1	368	30	stability	stability	NN
cord-309556-xv3413k1	368	31	after	after	IN
cord-309556-xv3413k1	368	32	cold	cold	JJ
cord-309556-xv3413k1	368	33	preservation	preservation	NN
cord-309556-xv3413k1	368	34	Single	single	JJ
cord-309556-xv3413k1	368	35	-	-	HYPH
cord-309556-xv3413k1	368	36	cell	cell	NN
cord-309556-xv3413k1	368	37	RNA	rna	NN
cord-309556-xv3413k1	368	38	expression	expression	NN
cord-309556-xv3413k1	368	39	profiling	profiling	NN
cord-309556-xv3413k1	368	40	of	of	IN
cord-309556-xv3413k1	368	41	ACE2	ACE2	NNP
cord-309556-xv3413k1	368	42	,	,	,
cord-309556-xv3413k1	368	43	the	the	DT
cord-309556-xv3413k1	368	44	putative	putative	JJ
cord-309556-xv3413k1	368	45	receptor	receptor	NN
cord-309556-xv3413k1	368	46	of	of	IN
cord-309556-xv3413k1	368	47	Wuhan	Wuhan	NNP
cord-309556-xv3413k1	368	48	Single	Single	NNP
cord-309556-xv3413k1	368	49	cell	cell	NN
cord-309556-xv3413k1	368	50	RNA	rna	NN
cord-309556-xv3413k1	368	51	sequencing	sequencing	NN
cord-309556-xv3413k1	368	52	of	of	IN
cord-309556-xv3413k1	368	53	13	13	CD
cord-309556-xv3413k1	368	54	human	human	JJ
cord-309556-xv3413k1	368	55	tissues	tissue	NNS
cord-309556-xv3413k1	368	56	identify	identify	VB
cord-309556-xv3413k1	368	57	cell	cell	NN
cord-309556-xv3413k1	368	58	types	type	NNS
cord-309556-xv3413k1	368	59	and	and	CC
cord-309556-xv3413k1	368	60	receptors	receptor	NNS
cord-309556-xv3413k1	368	61	of	of	IN
cord-309556-xv3413k1	368	62	human	human	JJ
cord-309556-xv3413k1	368	63	coronaviruses	coronaviruse	NNS
cord-309556-xv3413k1	368	64	Moderated	moderate	VBN
cord-309556-xv3413k1	368	65	estimation	estimation	NN
cord-309556-xv3413k1	368	66	of	of	IN
cord-309556-xv3413k1	368	67	fold	fold	JJ
cord-309556-xv3413k1	368	68	change	change	NN
cord-309556-xv3413k1	368	69	and	and	CC
cord-309556-xv3413k1	368	70	dispersion	dispersion	NN
cord-309556-xv3413k1	368	71	for	for	IN
cord-309556-xv3413k1	368	72	RNA	RNA	NNP
cord-309556-xv3413k1	368	73	-	-	HYPH
cord-309556-xv3413k1	368	74	seq	seq	NN
cord-309556-xv3413k1	368	75	data	datum	NNS
cord-309556-xv3413k1	368	76	with	with	IN
cord-309556-xv3413k1	368	77	DESeq2	DESeq2	NNP
cord-309556-xv3413k1	368	78	Effect	Effect	NNP
cord-309556-xv3413k1	368	79	of	of	IN
cord-309556-xv3413k1	368	80	aging	age	VBG
cord-309556-xv3413k1	368	81	on	on	IN
cord-309556-xv3413k1	368	82	respiratory	respiratory	JJ
cord-309556-xv3413k1	368	83	system	system	NN
cord-309556-xv3413k1	368	84	physiology	physiology	NN
cord-309556-xv3413k1	368	85	and	and	CC
cord-309556-xv3413k1	368	86	immunology	immunology	NN
cord-309556-xv3413k1	368	87	Alterations	alteration	NNS
cord-309556-xv3413k1	368	88	in	in	IN
cord-309556-xv3413k1	368	89	Platelet	Platelet	NNP
cord-309556-xv3413k1	368	90	Functions	function	NNS
cord-309556-xv3413k1	368	91	During	during	IN
cord-309556-xv3413k1	368	92	Aging	age	VBG
cord-309556-xv3413k1	368	93	:	:	:
cord-309556-xv3413k1	368	94	Clinical	clinical	JJ
cord-309556-xv3413k1	368	95	Correlations	correlation	NNS
cord-309556-xv3413k1	368	96	with	with	IN
cord-309556-xv3413k1	368	97	Thrombo	Thrombo	NNP
cord-309556-xv3413k1	368	98	-	-	HYPH
cord-309556-xv3413k1	368	99	Inflammatory	Inflammatory	NNP
cord-309556-xv3413k1	368	100	Disease	Disease	NNP
cord-309556-xv3413k1	368	101	in	in	IN
cord-309556-xv3413k1	368	102	Older	old	JJR
cord-309556-xv3413k1	368	103	Adults	Adults	NNPS
cord-309556-xv3413k1	369	1	A	a	DT
cord-309556-xv3413k1	369	2	crucial	crucial	JJ
cord-309556-xv3413k1	369	3	role	role	NN
cord-309556-xv3413k1	369	4	of	of	IN
cord-309556-xv3413k1	369	5	angiotensin	angiotensin	NN
cord-309556-xv3413k1	369	6	converting	convert	VBG
cord-309556-xv3413k1	369	7	enzyme	enzyme	NN
cord-309556-xv3413k1	369	8	2	2	CD
cord-309556-xv3413k1	369	9	(	(	-LRB-
cord-309556-xv3413k1	369	10	ACE2	ACE2	NNP
cord-309556-xv3413k1	369	11	)	)	-RRB-
cord-309556-xv3413k1	369	12	in	in	IN
cord-309556-xv3413k1	369	13	SARS	SARS	NNP
cord-309556-xv3413k1	369	14	coronavirus	coronavirus	NN
cord-309556-xv3413k1	369	15	-	-	HYPH
cord-309556-xv3413k1	369	16	induced	induce	VBN
cord-309556-xv3413k1	369	17	lung	lung	NN
cord-309556-xv3413k1	369	18	injury	injury	NN
cord-309556-xv3413k1	369	19	Angiotensin	Angiotensin	NNP
cord-309556-xv3413k1	369	20	-	-	HYPH
cord-309556-xv3413k1	369	21	converting	convert	VBG
cord-309556-xv3413k1	369	22	enzyme	enzyme	NN
cord-309556-xv3413k1	369	23	2	2	CD
cord-309556-xv3413k1	369	24	protects	protect	VBZ
cord-309556-xv3413k1	369	25	from	from	IN
cord-309556-xv3413k1	369	26	severe	severe	JJ
cord-309556-xv3413k1	369	27	acute	acute	JJ
cord-309556-xv3413k1	369	28	lung	lung	NN
cord-309556-xv3413k1	369	29	failure	failure	NN
cord-309556-xv3413k1	369	30	Identification	identification	NN
cord-309556-xv3413k1	369	31	of	of	IN
cord-309556-xv3413k1	369	32	a	a	DT
cord-309556-xv3413k1	369	33	Novel	Novel	NNP
cord-309556-xv3413k1	369	34	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	369	35	in	in	IN
cord-309556-xv3413k1	369	36	Patients	patient	NNS
cord-309556-xv3413k1	369	37	with	with	IN
cord-309556-xv3413k1	369	38	Severe	severe	JJ
cord-309556-xv3413k1	369	39	Acute	acute	JJ
cord-309556-xv3413k1	369	40	Respiratory	respiratory	JJ
cord-309556-xv3413k1	369	41	Syndrome	syndrome	NN
cord-309556-xv3413k1	370	1	A	a	DT
cord-309556-xv3413k1	370	2	Novel	Novel	NNP
cord-309556-xv3413k1	370	3	Angiotensin	Angiotensin	NNP
cord-309556-xv3413k1	370	4	-	-	HYPH
cord-309556-xv3413k1	370	5	Converting	convert	VBG
cord-309556-xv3413k1	370	6	Enzyme	Enzyme	NNP
cord-309556-xv3413k1	370	7	-	-	HYPH
cord-309556-xv3413k1	370	8	Related	relate	VBN
cord-309556-xv3413k1	370	9	Carboxypeptidase	Carboxypeptidase	NNP
cord-309556-xv3413k1	370	10	(	(	-LRB-
cord-309556-xv3413k1	370	11	ACE2	ACE2	NNP
cord-309556-xv3413k1	370	12	)	)	-RRB-
cord-309556-xv3413k1	371	1	Converts	convert	VBZ
cord-309556-xv3413k1	371	2	Angiotensin	angiotensin	NN
cord-309556-xv3413k1	371	3	I	-PRON-	PRP
cord-309556-xv3413k1	371	4	to	to	IN
cord-309556-xv3413k1	372	1	Angiotensin	angiotensin	NN
cord-309556-xv3413k1	372	2	1	1	CD
cord-309556-xv3413k1	373	1	-9	-9	NNP
cord-309556-xv3413k1	373	2	A	a	DT
cord-309556-xv3413k1	373	3	Human	human	JJ
cord-309556-xv3413k1	373	4	Homolog	Homolog	NNP
cord-309556-xv3413k1	373	5	of	of	IN
cord-309556-xv3413k1	373	6	Angiotensin	Angiotensin	NNP
cord-309556-xv3413k1	373	7	-	-	HYPH
cord-309556-xv3413k1	373	8	converting	convert	VBG
cord-309556-xv3413k1	373	9	Enzyme	enzyme	NN
cord-309556-xv3413k1	373	10	CLONING	cloning	NN
cord-309556-xv3413k1	373	11	AND	and	CC
cord-309556-xv3413k1	373	12	FUNCTIONAL	functional	JJ
cord-309556-xv3413k1	373	13	EXPRESSION	expression	NN
cord-309556-xv3413k1	374	1	AS	as	IN
cord-309556-xv3413k1	375	1	A	a	DT
cord-309556-xv3413k1	375	2	CAPTOPRIL	CAPTOPRIL	NNP
cord-309556-xv3413k1	375	3	-	-	HYPH
cord-309556-xv3413k1	375	4	INSENSITIVE	INSENSITIVE	NNP
cord-309556-xv3413k1	375	5	Angiotensin	Angiotensin	NNP
cord-309556-xv3413k1	375	6	-	-	HYPH
cord-309556-xv3413k1	375	7	converting	convert	VBG
cord-309556-xv3413k1	375	8	enzyme	enzyme	NN
cord-309556-xv3413k1	375	9	2	2	CD
cord-309556-xv3413k1	375	10	is	be	VBZ
cord-309556-xv3413k1	375	11	an	an	DT
cord-309556-xv3413k1	375	12	essential	essential	JJ
cord-309556-xv3413k1	375	13	regulator	regulator	NN
cord-309556-xv3413k1	375	14	of	of	IN
cord-309556-xv3413k1	375	15	heart	heart	NN
cord-309556-xv3413k1	375	16	function	function	NN
cord-309556-xv3413k1	375	17	Clinical	clinical	JJ
cord-309556-xv3413k1	375	18	Characteristics	characteristic	NNS
cord-309556-xv3413k1	375	19	of	of	IN
cord-309556-xv3413k1	375	20	138	138	CD
cord-309556-xv3413k1	375	21	Hospitalized	hospitalize	VBN
cord-309556-xv3413k1	375	22	Patients	patient	NNS
cord-309556-xv3413k1	375	23	With	with	IN
cord-309556-xv3413k1	375	24	2019	2019	CD
cord-309556-xv3413k1	375	25	Novel	Novel	NNP
cord-309556-xv3413k1	375	26	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	375	27	-	-	HYPH
cord-309556-xv3413k1	375	28	Infected	infect	VBN
cord-309556-xv3413k1	375	29	Pneumonia	Pneumonia	NNP
cord-309556-xv3413k1	375	30	in	in	IN
cord-309556-xv3413k1	375	31	Wuhan	Wuhan	NNP
cord-309556-xv3413k1	375	32	,	,	,
cord-309556-xv3413k1	375	33	China	China	NNP
cord-309556-xv3413k1	375	34	Baseline	Baseline	NNP
cord-309556-xv3413k1	375	35	Characteristics	Characteristics	NNP
cord-309556-xv3413k1	375	36	and	and	CC
cord-309556-xv3413k1	375	37	Outcomes	Outcomes	NNPS
cord-309556-xv3413k1	375	38	of	of	IN
cord-309556-xv3413k1	375	39	1591	1591	CD
cord-309556-xv3413k1	375	40	Patients	patient	NNS
cord-309556-xv3413k1	375	41	Infected	infect	VBN
cord-309556-xv3413k1	375	42	With	with	IN
cord-309556-xv3413k1	375	43	SARS	SARS	NNP
cord-309556-xv3413k1	375	44	-	-	HYPH
cord-309556-xv3413k1	375	45	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	376	1	Admitted	admit	VBN
cord-309556-xv3413k1	376	2	to	to	IN
cord-309556-xv3413k1	376	3	ICUs	ICUs	NNP
cord-309556-xv3413k1	376	4	of	of	IN
cord-309556-xv3413k1	376	5	the	the	DT
cord-309556-xv3413k1	376	6	Lombardy	Lombardy	NNP
cord-309556-xv3413k1	376	7	Region	Region	NNP
cord-309556-xv3413k1	377	1	The	the	DT
cord-309556-xv3413k1	377	2	Mitochondrial	Mitochondrial	NNP
cord-309556-xv3413k1	377	3	Basis	Basis	NNP
cord-309556-xv3413k1	377	4	of	of	IN
cord-309556-xv3413k1	377	5	Aging	Aging	NNP
cord-309556-xv3413k1	377	6	and	and	CC
cord-309556-xv3413k1	377	7	Age	Age	NNP
cord-309556-xv3413k1	377	8	-	-	HYPH
cord-309556-xv3413k1	377	9	Related	relate	VBN
cord-309556-xv3413k1	377	10	Disorders	disorder	NNS
cord-309556-xv3413k1	378	1	The	the	DT
cord-309556-xv3413k1	378	2	Mitochondrial	Mitochondrial	NNP
cord-309556-xv3413k1	378	3	Basis	Basis	NNP
cord-309556-xv3413k1	378	4	of	of	IN
cord-309556-xv3413k1	378	5	Aging	age	VBG
cord-309556-xv3413k1	378	6	Mitochondrial	mitochondrial	JJ
cord-309556-xv3413k1	378	7	dysfunction	dysfunction	NN
cord-309556-xv3413k1	378	8	in	in	IN
cord-309556-xv3413k1	378	9	the	the	DT
cord-309556-xv3413k1	378	10	elderly	elderly	JJ
cord-309556-xv3413k1	378	11	:	:	:
cord-309556-xv3413k1	378	12	possible	possible	JJ
cord-309556-xv3413k1	378	13	role	role	NN
cord-309556-xv3413k1	378	14	in	in	IN
cord-309556-xv3413k1	378	15	insulin	insulin	NN
cord-309556-xv3413k1	378	16	resistance	resistance	NN
cord-309556-xv3413k1	378	17	Lipid	lipid	NN
cord-309556-xv3413k1	378	18	rafts	raft	NNS
cord-309556-xv3413k1	378	19	are	be	VBP
cord-309556-xv3413k1	378	20	involved	involve	VBN
cord-309556-xv3413k1	378	21	in	in	IN
cord-309556-xv3413k1	378	22	SARS	SARS	NNP
cord-309556-xv3413k1	378	23	-	-	HYPH
cord-309556-xv3413k1	378	24	CoV	CoV	NNP
cord-309556-xv3413k1	378	25	entry	entry	NN
cord-309556-xv3413k1	378	26	into	into	IN
cord-309556-xv3413k1	378	27	Vero	Vero	NNP
cord-309556-xv3413k1	378	28	E6	E6	NNP
cord-309556-xv3413k1	378	29	cells	cell	NNS
cord-309556-xv3413k1	378	30	SARS	SARS	NNP
cord-309556-xv3413k1	378	31	coronavirus	coronavirus	NN
cord-309556-xv3413k1	378	32	entry	entry	NN
cord-309556-xv3413k1	378	33	into	into	IN
cord-309556-xv3413k1	378	34	host	host	NN
cord-309556-xv3413k1	378	35	cells	cell	NNS
cord-309556-xv3413k1	378	36	through	through	IN
cord-309556-xv3413k1	378	37	a	a	DT
cord-309556-xv3413k1	378	38	novel	novel	JJ
cord-309556-xv3413k1	378	39	clathrin	clathrin	NN
cord-309556-xv3413k1	378	40	-	-	:
cord-309556-xv3413k1	378	41	and	and	CC
cord-309556-xv3413k1	378	42	caveolaeindependent	caveolaeindependent	NN
cord-309556-xv3413k1	378	43	endocytic	endocytic	JJ
cord-309556-xv3413k1	378	44	pathway	pathway	NN
cord-309556-xv3413k1	378	45	Lipid	Lipid	NNP
cord-309556-xv3413k1	378	46	rafts	raft	NNS
cord-309556-xv3413k1	378	47	play	play	VBP
cord-309556-xv3413k1	378	48	an	an	DT
cord-309556-xv3413k1	378	49	important	important	JJ
cord-309556-xv3413k1	378	50	role	role	NN
cord-309556-xv3413k1	378	51	in	in	IN
cord-309556-xv3413k1	378	52	the	the	DT
cord-309556-xv3413k1	378	53	early	early	JJ
cord-309556-xv3413k1	378	54	stage	stage	NN
cord-309556-xv3413k1	378	55	of	of	IN
cord-309556-xv3413k1	378	56	severe	severe	JJ
cord-309556-xv3413k1	378	57	acute	acute	JJ
cord-309556-xv3413k1	378	58	respiratory	respiratory	JJ
cord-309556-xv3413k1	378	59	syndrome	syndrome	NN
cord-309556-xv3413k1	378	60	-	-	HYPH
cord-309556-xv3413k1	378	61	coronavirus	coronavirus	NN
cord-309556-xv3413k1	378	62	life	life	NN
cord-309556-xv3413k1	378	63	cycle	cycle	NN
cord-309556-xv3413k1	378	64	Lipid	Lipid	NNP
cord-309556-xv3413k1	378	65	rafts	raft	NNS
cord-309556-xv3413k1	378	66	:	:	:
cord-309556-xv3413k1	378	67	heterogeneity	heterogeneity	NN
cord-309556-xv3413k1	378	68	on	on	IN
cord-309556-xv3413k1	378	69	the	the	DT
cord-309556-xv3413k1	378	70	high	high	JJ
cord-309556-xv3413k1	378	71	seas	sea	NNS
cord-309556-xv3413k1	378	72	SARS	SARS	NNP
cord-309556-xv3413k1	378	73	coronavirus	coronavirus	NN
cord-309556-xv3413k1	378	74	,	,	,
cord-309556-xv3413k1	378	75	but	but	CC
cord-309556-xv3413k1	378	76	not	not	RB
cord-309556-xv3413k1	378	77	human	human	JJ
cord-309556-xv3413k1	378	78	coronavirus	coronavirus	NN
cord-309556-xv3413k1	379	1	NL63	NL63	NNP
cord-309556-xv3413k1	379	2	,	,	,
cord-309556-xv3413k1	379	3	utilizes	utilize	VBZ
cord-309556-xv3413k1	379	4	cathepsin	cathepsin	NN
cord-309556-xv3413k1	379	5	L	l	NN
cord-309556-xv3413k1	379	6	to	to	TO
cord-309556-xv3413k1	379	7	infect	infect	VB
cord-309556-xv3413k1	379	8	ACE2-expressing	ace2-expressing	NN
cord-309556-xv3413k1	379	9	cells	cell	NNS
cord-309556-xv3413k1	379	10	Inhibitors	inhibitor	NNS
cord-309556-xv3413k1	379	11	of	of	IN
cord-309556-xv3413k1	379	12	cathepsin	cathepsin	NN
cord-309556-xv3413k1	380	1	L	l	NN
cord-309556-xv3413k1	380	2	prevent	prevent	VBP
cord-309556-xv3413k1	380	3	severe	severe	JJ
cord-309556-xv3413k1	380	4	acute	acute	JJ
cord-309556-xv3413k1	380	5	respiratory	respiratory	JJ
cord-309556-xv3413k1	380	6	syndrome	syndrome	NN
cord-309556-xv3413k1	380	7	coronavirus	coronavirus	NN
cord-309556-xv3413k1	380	8	entry	entry	NN
cord-309556-xv3413k1	380	9	A	a	DT
cord-309556-xv3413k1	380	10	molecular	molecular	JJ
cord-309556-xv3413k1	380	11	cell	cell	NN
cord-309556-xv3413k1	380	12	atlas	atlas	NN
cord-309556-xv3413k1	380	13	of	of	IN
cord-309556-xv3413k1	380	14	the	the	DT
cord-309556-xv3413k1	380	15	human	human	JJ
cord-309556-xv3413k1	380	16	lung	lung	NN
cord-309556-xv3413k1	380	17	from	from	IN
cord-309556-xv3413k1	380	18	single	single	JJ
cord-309556-xv3413k1	380	19	cell	cell	NN
cord-309556-xv3413k1	380	20	RNA	rna	NN
cord-309556-xv3413k1	380	21	sequencing	sequence	VBG
cord-309556-xv3413k1	380	22	Molecular	molecular	JJ
cord-309556-xv3413k1	380	23	pathology	pathology	NN
cord-309556-xv3413k1	380	24	of	of	IN
cord-309556-xv3413k1	380	25	emerging	emerge	VBG
cord-309556-xv3413k1	380	26	coronavirus	coronavirus	NN
cord-309556-xv3413k1	380	27	infections	infection	NNS
cord-309556-xv3413k1	380	28	Clinical	clinical	JJ
cord-309556-xv3413k1	380	29	progression	progression	NN
cord-309556-xv3413k1	380	30	and	and	CC
cord-309556-xv3413k1	380	31	viral	viral	JJ
cord-309556-xv3413k1	380	32	load	load	NN
cord-309556-xv3413k1	380	33	in	in	IN
cord-309556-xv3413k1	380	34	a	a	DT
cord-309556-xv3413k1	380	35	community	community	NN
cord-309556-xv3413k1	380	36	outbreak	outbreak	NN
cord-309556-xv3413k1	380	37	of	of	IN
cord-309556-xv3413k1	380	38	coronavirus	coronavirus	NN
cord-309556-xv3413k1	380	39	-	-	HYPH
cord-309556-xv3413k1	380	40	associated	associate	VBN
cord-309556-xv3413k1	380	41	SARS	SARS	NNP
cord-309556-xv3413k1	380	42	pneumonia	pneumonia	NN
cord-309556-xv3413k1	380	43	:	:	:
cord-309556-xv3413k1	381	1	a	a	DT
cord-309556-xv3413k1	381	2	prospective	prospective	JJ
cord-309556-xv3413k1	381	3	study	study	NN
cord-309556-xv3413k1	381	4	xCell	xCell	NNP
cord-309556-xv3413k1	381	5	:	:	:
cord-309556-xv3413k1	381	6	digitally	digitally	RB
cord-309556-xv3413k1	381	7	portraying	portray	VBG
cord-309556-xv3413k1	381	8	the	the	DT
cord-309556-xv3413k1	381	9	tissue	tissue	NN
cord-309556-xv3413k1	381	10	cellular	cellular	JJ
cord-309556-xv3413k1	381	11	heterogeneity	heterogeneity	NN
cord-309556-xv3413k1	381	12	landscape	landscape	NN
cord-309556-xv3413k1	381	13	Regeneration	regeneration	NN
cord-309556-xv3413k1	381	14	of	of	IN
cord-309556-xv3413k1	381	15	the	the	DT
cord-309556-xv3413k1	381	16	Aging	age	VBG
cord-309556-xv3413k1	381	17	Lung	Lung	NNP
cord-309556-xv3413k1	381	18	:	:	:
cord-309556-xv3413k1	382	1	A	a	DT
cord-309556-xv3413k1	382	2	Mini	Mini	NNP
cord-309556-xv3413k1	382	3	-	-	NNP
cord-309556-xv3413k1	382	4	Review	review	NN
cord-309556-xv3413k1	383	1	The	the	DT
cord-309556-xv3413k1	383	2	aging	age	VBG
cord-309556-xv3413k1	383	3	lung	lung	NN
cord-309556-xv3413k1	383	4	Pulmonary	pulmonary	JJ
cord-309556-xv3413k1	383	5	macrophages	macrophage	NNS
cord-309556-xv3413k1	383	6	:	:	:
cord-309556-xv3413k1	383	7	key	key	JJ
cord-309556-xv3413k1	383	8	players	player	NNS
cord-309556-xv3413k1	383	9	in	in	IN
cord-309556-xv3413k1	383	10	the	the	DT
cord-309556-xv3413k1	383	11	innate	innate	JJ
cord-309556-xv3413k1	383	12	defence	defence	NN
cord-309556-xv3413k1	383	13	of	of	IN
cord-309556-xv3413k1	383	14	the	the	DT
cord-309556-xv3413k1	383	15	airways	airways	NNPS
cord-309556-xv3413k1	384	1	The	the	DT
cord-309556-xv3413k1	384	2	clinical	clinical	JJ
cord-309556-xv3413k1	384	3	pathology	pathology	NN
cord-309556-xv3413k1	384	4	of	of	IN
cord-309556-xv3413k1	384	5	severe	severe	JJ
cord-309556-xv3413k1	384	6	acute	acute	JJ
cord-309556-xv3413k1	384	7	respiratory	respiratory	JJ
cord-309556-xv3413k1	384	8	syndrome	syndrome	NN
cord-309556-xv3413k1	384	9	(	(	-LRB-
cord-309556-xv3413k1	384	10	SARS	SARS	NNP
cord-309556-xv3413k1	384	11	)	)	-RRB-
cord-309556-xv3413k1	384	12	:	:	:
cord-309556-xv3413k1	385	1	a	a	DT
cord-309556-xv3413k1	385	2	report	report	NN
cord-309556-xv3413k1	385	3	from	from	IN
cord-309556-xv3413k1	385	4	Evolution	evolution	NN
cord-309556-xv3413k1	385	5	of	of	IN
cord-309556-xv3413k1	385	6	pulmonary	pulmonary	JJ
cord-309556-xv3413k1	385	7	pathology	pathology	NN
cord-309556-xv3413k1	385	8	in	in	IN
cord-309556-xv3413k1	385	9	severe	severe	JJ
cord-309556-xv3413k1	385	10	acute	acute	JJ
cord-309556-xv3413k1	385	11	respiratory	respiratory	JJ
cord-309556-xv3413k1	385	12	syndrome	syndrome	NN
cord-309556-xv3413k1	385	13	Regulating	regulate	VBG
cord-309556-xv3413k1	385	14	the	the	DT
cord-309556-xv3413k1	385	15	adaptive	adaptive	JJ
cord-309556-xv3413k1	385	16	immune	immune	JJ
cord-309556-xv3413k1	385	17	response	response	NN
cord-309556-xv3413k1	385	18	to	to	IN
cord-309556-xv3413k1	385	19	respiratory	respiratory	JJ
cord-309556-xv3413k1	385	20	virus	virus	NN
cord-309556-xv3413k1	385	21	infection	infection	NN
cord-309556-xv3413k1	385	22	Regulation	regulation	NN
cord-309556-xv3413k1	385	23	of	of	IN
cord-309556-xv3413k1	385	24	immunological	immunological	JJ
cord-309556-xv3413k1	385	25	homeostasis	homeostasis	NN
cord-309556-xv3413k1	385	26	in	in	IN
cord-309556-xv3413k1	385	27	the	the	DT
cord-309556-xv3413k1	385	28	respiratory	respiratory	JJ
cord-309556-xv3413k1	385	29	tract	tract	NN
cord-309556-xv3413k1	385	30	Alveolar	alveolar	NN
cord-309556-xv3413k1	385	31	Macrophages	Macrophages	NNPS
cord-309556-xv3413k1	385	32	in	in	IN
cord-309556-xv3413k1	385	33	the	the	DT
cord-309556-xv3413k1	385	34	Resolution	Resolution	NNP
cord-309556-xv3413k1	385	35	of	of	IN
cord-309556-xv3413k1	385	36	Inflammation	inflammation	NN
cord-309556-xv3413k1	385	37	,	,	,
cord-309556-xv3413k1	385	38	Tissue	tissue	NN
cord-309556-xv3413k1	385	39	Repair	Repair	NNP
cord-309556-xv3413k1	385	40	,	,	,
cord-309556-xv3413k1	385	41	and	and	CC
cord-309556-xv3413k1	385	42	Tolerance	tolerance	NN
cord-309556-xv3413k1	385	43	to	to	IN
cord-309556-xv3413k1	385	44	Infection	Infection	NNP
cord-309556-xv3413k1	385	45	Antibody	antibody	NN
cord-309556-xv3413k1	385	46	-	-	HYPH
cord-309556-xv3413k1	385	47	dependent	dependent	JJ
cord-309556-xv3413k1	385	48	infection	infection	NN
cord-309556-xv3413k1	385	49	of	of	IN
cord-309556-xv3413k1	385	50	human	human	JJ
cord-309556-xv3413k1	385	51	macrophages	macrophage	NNS
cord-309556-xv3413k1	385	52	by	by	IN
cord-309556-xv3413k1	385	53	severe	severe	JJ
cord-309556-xv3413k1	385	54	acute	acute	JJ
cord-309556-xv3413k1	385	55	respiratory	respiratory	JJ
cord-309556-xv3413k1	385	56	syndrome	syndrome	NN
cord-309556-xv3413k1	385	57	coronavirus	coronavirus	NN
cord-309556-xv3413k1	385	58	Cytokine	cytokine	NN
cord-309556-xv3413k1	385	59	Responses	response	NNS
cord-309556-xv3413k1	385	60	in	in	IN
cord-309556-xv3413k1	385	61	Severe	severe	JJ
cord-309556-xv3413k1	385	62	Acute	acute	JJ
cord-309556-xv3413k1	385	63	Respiratory	Respiratory	NNP
cord-309556-xv3413k1	385	64	Syndrome	Syndrome	NNP
cord-309556-xv3413k1	385	65	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	385	66	-	-	HYPH
cord-309556-xv3413k1	385	67	Infected	infect	VBN
cord-309556-xv3413k1	385	68	Macrophages	macrophage	NNS
cord-309556-xv3413k1	386	1	In	in	IN
cord-309556-xv3413k1	386	2	Vitro	Vitro	NNP
cord-309556-xv3413k1	386	3	:	:	:
cord-309556-xv3413k1	387	1	Possible	possible	JJ
cord-309556-xv3413k1	387	2	Relevance	relevance	NN
cord-309556-xv3413k1	387	3	to	to	IN
cord-309556-xv3413k1	387	4	Pathogenesis	Pathogenesis	NNP
cord-309556-xv3413k1	387	5	Alveolar	Alveolar	NNP
cord-309556-xv3413k1	387	6	macrophage	macrophage	NN
cord-309556-xv3413k1	387	7	elimination	elimination	NN
cord-309556-xv3413k1	387	8	in	in	IN
cord-309556-xv3413k1	387	9	vivo	vivo	NN
cord-309556-xv3413k1	387	10	is	be	VBZ
cord-309556-xv3413k1	387	11	associated	associate	VBN
cord-309556-xv3413k1	387	12	with	with	IN
cord-309556-xv3413k1	387	13	an	an	DT
cord-309556-xv3413k1	387	14	increase	increase	NN
cord-309556-xv3413k1	387	15	in	in	IN
cord-309556-xv3413k1	387	16	pulmonary	pulmonary	JJ
cord-309556-xv3413k1	387	17	immune	immune	JJ
cord-309556-xv3413k1	387	18	response	response	NN
cord-309556-xv3413k1	387	19	in	in	IN
cord-309556-xv3413k1	387	20	mice	mouse	NNS
cord-309556-xv3413k1	387	21	Evasion	evasion	NN
cord-309556-xv3413k1	387	22	by	by	IN
cord-309556-xv3413k1	387	23	stealth	stealth	NN
cord-309556-xv3413k1	387	24	:	:	:
cord-309556-xv3413k1	387	25	inefficient	inefficient	JJ
cord-309556-xv3413k1	387	26	immune	immune	JJ
cord-309556-xv3413k1	387	27	activation	activation	NN
cord-309556-xv3413k1	387	28	underlies	underlie	VBZ
cord-309556-xv3413k1	387	29	poor	poor	JJ
cord-309556-xv3413k1	387	30	T	T	NNP
cord-309556-xv3413k1	387	31	cell	cell	NN
cord-309556-xv3413k1	387	32	response	response	NN
cord-309556-xv3413k1	387	33	and	and	CC
cord-309556-xv3413k1	387	34	severe	severe	JJ
cord-309556-xv3413k1	387	35	disease	disease	NN
cord-309556-xv3413k1	387	36	in	in	IN
cord-309556-xv3413k1	387	37	SARS	SARS	NNP
cord-309556-xv3413k1	387	38	-	-	HYPH
cord-309556-xv3413k1	387	39	CoV	CoV	NNP
cord-309556-xv3413k1	387	40	Macrophage	macrophage	NN
cord-309556-xv3413k1	387	41	plasticity	plasticity	NN
cord-309556-xv3413k1	387	42	,	,	,
cord-309556-xv3413k1	387	43	polarization	polarization	NN
cord-309556-xv3413k1	387	44	,	,	,
cord-309556-xv3413k1	387	45	and	and	CC
cord-309556-xv3413k1	387	46	function	function	VB
cord-309556-xv3413k1	387	47	in	in	IN
cord-309556-xv3413k1	387	48	health	health	NN
cord-309556-xv3413k1	387	49	and	and	CC
cord-309556-xv3413k1	387	50	disease	disease	NN
cord-309556-xv3413k1	387	51	T	T	NNP
cord-309556-xv3413k1	387	52	cell	cell	NN
cord-309556-xv3413k1	387	53	responses	response	NNS
cord-309556-xv3413k1	387	54	are	be	VBP
cord-309556-xv3413k1	387	55	required	require	VBN
cord-309556-xv3413k1	387	56	for	for	IN
cord-309556-xv3413k1	387	57	protection	protection	NN
cord-309556-xv3413k1	387	58	from	from	IN
cord-309556-xv3413k1	387	59	clinical	clinical	JJ
cord-309556-xv3413k1	387	60	disease	disease	NN
cord-309556-xv3413k1	387	61	and	and	CC
cord-309556-xv3413k1	387	62	for	for	IN
cord-309556-xv3413k1	387	63	virus	virus	NN
cord-309556-xv3413k1	387	64	clearance	clearance	NN
cord-309556-xv3413k1	387	65	in	in	IN
cord-309556-xv3413k1	387	66	severe	severe	JJ
cord-309556-xv3413k1	387	67	acute	acute	JJ
cord-309556-xv3413k1	387	68	respiratory	respiratory	JJ
cord-309556-xv3413k1	387	69	syndrome	syndrome	NN
cord-309556-xv3413k1	387	70	coronavirus	coronavirus	NN
cord-309556-xv3413k1	387	71	-	-	HYPH
cord-309556-xv3413k1	387	72	infected	infect	VBN
cord-309556-xv3413k1	387	73	mice	mouse	NNS
cord-309556-xv3413k1	388	1	Cellular	cellular	JJ
cord-309556-xv3413k1	388	2	immune	immune	JJ
cord-309556-xv3413k1	388	3	responses	response	NNS
cord-309556-xv3413k1	388	4	to	to	IN
cord-309556-xv3413k1	388	5	severe	severe	JJ
cord-309556-xv3413k1	388	6	acute	acute	JJ
cord-309556-xv3413k1	388	7	respiratory	respiratory	JJ
cord-309556-xv3413k1	388	8	syndrome	syndrome	NN
cord-309556-xv3413k1	388	9	coronavirus	coronavirus	NN
cord-309556-xv3413k1	388	10	(	(	-LRB-
cord-309556-xv3413k1	388	11	SARS	SARS	NNP
cord-309556-xv3413k1	388	12	-	-	HYPH
cord-309556-xv3413k1	388	13	CoV	CoV	NNP
cord-309556-xv3413k1	388	14	)	)	-RRB-
cord-309556-xv3413k1	388	15	infection	infection	NN
cord-309556-xv3413k1	388	16	in	in	IN
cord-309556-xv3413k1	388	17	senescent	senescent	JJ
cord-309556-xv3413k1	388	18	BALB	BALB	NNP
cord-309556-xv3413k1	388	19	/	/	SYM
cord-309556-xv3413k1	388	20	c	c	NN
cord-309556-xv3413k1	388	21	mice	mouse	NNS
cord-309556-xv3413k1	388	22	:	:	:
cord-309556-xv3413k1	388	23	CD4	CD4	NNP
cord-309556-xv3413k1	388	24	+	+	CC
cord-309556-xv3413k1	388	25	T	t	NN
cord-309556-xv3413k1	388	26	cells	cell	NNS
cord-309556-xv3413k1	388	27	are	be	VBP
cord-309556-xv3413k1	388	28	important	important	JJ
cord-309556-xv3413k1	388	29	in	in	IN
cord-309556-xv3413k1	388	30	control	control	NN
cord-309556-xv3413k1	388	31	of	of	IN
cord-309556-xv3413k1	388	32	SARS	SARS	NNP
cord-309556-xv3413k1	388	33	-	-	HYPH
cord-309556-xv3413k1	388	34	CoV	CoV	NNP
cord-309556-xv3413k1	388	35	infection	infection	NN
cord-309556-xv3413k1	388	36	Induction	Induction	NNP
cord-309556-xv3413k1	388	37	of	of	IN
cord-309556-xv3413k1	388	38	Th1	Th1	NNP
cord-309556-xv3413k1	388	39	type	type	NN
cord-309556-xv3413k1	388	40	response	response	NN
cord-309556-xv3413k1	388	41	by	by	IN
cord-309556-xv3413k1	388	42	DNA	dna	NN
cord-309556-xv3413k1	388	43	vaccinations	vaccination	NNS
cord-309556-xv3413k1	388	44	with	with	IN
cord-309556-xv3413k1	388	45	N	N	NNP
cord-309556-xv3413k1	388	46	,	,	,
cord-309556-xv3413k1	388	47	M	M	NNP
cord-309556-xv3413k1	388	48	,	,	,
cord-309556-xv3413k1	388	49	and	and	CC
cord-309556-xv3413k1	388	50	E	e	NN
cord-309556-xv3413k1	388	51	genes	gene	NNS
cord-309556-xv3413k1	388	52	against	against	IN
cord-309556-xv3413k1	388	53	SARS	SARS	NNP
cord-309556-xv3413k1	388	54	-	-	HYPH
cord-309556-xv3413k1	388	55	CoV	CoV	NNP
cord-309556-xv3413k1	388	56	in	in	IN
cord-309556-xv3413k1	388	57	mice	mouse	NNS
cord-309556-xv3413k1	389	1	Expanding	expand	VBG
cord-309556-xv3413k1	389	2	roles	role	NNS
cord-309556-xv3413k1	389	3	for	for	IN
cord-309556-xv3413k1	389	4	CD4	CD4	NNP
cord-309556-xv3413k1	389	5	+	+	CC
cord-309556-xv3413k1	389	6	T	t	NN
cord-309556-xv3413k1	389	7	cells	cell	NNS
cord-309556-xv3413k1	389	8	in	in	IN
cord-309556-xv3413k1	389	9	immunity	immunity	NN
cord-309556-xv3413k1	389	10	to	to	IN
cord-309556-xv3413k1	389	11	viruses	virus	NNS
cord-309556-xv3413k1	390	1	A	a	DT
cord-309556-xv3413k1	390	2	Kinome	Kinome	NNP
cord-309556-xv3413k1	390	3	-	-	HYPH
cord-309556-xv3413k1	390	4	Wide	wide	JJ
cord-309556-xv3413k1	390	5	Small	small	JJ
cord-309556-xv3413k1	390	6	Interfering	Interfering	NNP
cord-309556-xv3413k1	390	7	RNA	RNA	NNP
cord-309556-xv3413k1	390	8	Screen	Screen	NNP
cord-309556-xv3413k1	390	9	Identifies	identify	VBZ
cord-309556-xv3413k1	390	10	Proviral	Proviral	NNP
cord-309556-xv3413k1	390	11	and	and	CC
cord-309556-xv3413k1	390	12	Antiviral	Antiviral	NNP
cord-309556-xv3413k1	390	13	Host	Host	NNP
cord-309556-xv3413k1	390	14	Factors	Factors	NNP
cord-309556-xv3413k1	390	15	in	in	IN
cord-309556-xv3413k1	390	16	Severe	severe	JJ
cord-309556-xv3413k1	390	17	Acute	acute	JJ
cord-309556-xv3413k1	390	18	Respiratory	Respiratory	NNP
cord-309556-xv3413k1	390	19	Syndrome	Syndrome	NNP
cord-309556-xv3413k1	390	20	Coronavirus	Coronavirus	NNP
cord-309556-xv3413k1	390	21	Replication	Replication	NNP
cord-309556-xv3413k1	390	22	,	,	,
cord-309556-xv3413k1	391	1	Including	include	VBG
cord-309556-xv3413k1	391	2	Double	Double	NNP
cord-309556-xv3413k1	391	3	-	-	HYPH
cord-309556-xv3413k1	391	4	Stranded	Stranded	NNP
cord-309556-xv3413k1	391	5	RNA	RNA	NNP
cord-309556-xv3413k1	391	6	-	-	HYPH
cord-309556-xv3413k1	391	7	Activated	Activated	NNP
cord-309556-xv3413k1	391	8	Protein	Protein	NNP
cord-309556-xv3413k1	391	9	Kinase	Kinase	NNP
cord-309556-xv3413k1	391	10	and	and	CC
cord-309556-xv3413k1	391	11	Early	early	JJ
cord-309556-xv3413k1	391	12	Secretory	Secretory	NNP
cord-309556-xv3413k1	391	13	Pathway	Pathway	NNP
cord-309556-xv3413k1	391	14	Proteins	protein	NNS
cord-309556-xv3413k1	392	1	A	a	DT
cord-309556-xv3413k1	392	2	SARS	SARS	NNP
cord-309556-xv3413k1	392	3	-	-	HYPH
cord-309556-xv3413k1	392	4	CoV-2-Human	CoV-2-Human	NNP
cord-309556-xv3413k1	392	5	Protein	Protein	NNP
cord-309556-xv3413k1	392	6	-	-	HYPH
cord-309556-xv3413k1	392	7	Protein	Protein	NNP
cord-309556-xv3413k1	392	8	Interaction	Interaction	NNP
cord-309556-xv3413k1	392	9	Map	Map	NNP
cord-309556-xv3413k1	392	10	Reveals	reveal	VBZ
cord-309556-xv3413k1	392	11	Drug	Drug	NNP
cord-309556-xv3413k1	392	12	Targets	Targets	NNPS
cord-309556-xv3413k1	392	13	and	and	CC
cord-309556-xv3413k1	392	14	Potential	Potential	NNP
cord-309556-xv3413k1	392	15	Drug	Drug	NNP
cord-309556-xv3413k1	392	16	-	-	HYPH
cord-309556-xv3413k1	392	17	Repurposing	repurpose	VBG
cord-309556-xv3413k1	392	18	Protein	Protein	NNP
cord-309556-xv3413k1	392	19	associated	associate	VBN
cord-309556-xv3413k1	392	20	with	with	IN
cord-309556-xv3413k1	392	21	Myc	Myc	NNP
cord-309556-xv3413k1	392	22	(	(	-LRB-
cord-309556-xv3413k1	392	23	PAM	PAM	NNP
cord-309556-xv3413k1	392	24	)	)	-RRB-
cord-309556-xv3413k1	392	25	is	be	VBZ
cord-309556-xv3413k1	392	26	a	a	DT
cord-309556-xv3413k1	392	27	potent	potent	JJ
cord-309556-xv3413k1	392	28	inhibitor	inhibitor	NN
cord-309556-xv3413k1	392	29	of	of	IN
cord-309556-xv3413k1	392	30	adenylyl	adenylyl	NNP
cord-309556-xv3413k1	392	31	cyclases	cyclases	NNP
cord-309556-xv3413k1	393	1	PAM	PAM	NNP
cord-309556-xv3413k1	393	2	mediates	mediate	VBZ
cord-309556-xv3413k1	393	3	sustained	sustain	VBN
cord-309556-xv3413k1	393	4	inhibition	inhibition	NN
cord-309556-xv3413k1	393	5	of	of	IN
cord-309556-xv3413k1	393	6	cAMP	camp	NN
cord-309556-xv3413k1	393	7	signaling	signaling	NN
cord-309556-xv3413k1	393	8	by	by	IN
cord-309556-xv3413k1	393	9	sphingosine-1-phosphate	sphingosine-1-phosphate	NNP
cord-309556-xv3413k1	393	10	cAMP	camp	NN
cord-309556-xv3413k1	393	11	Regulation	regulation	NN
cord-309556-xv3413k1	393	12	of	of	IN
cord-309556-xv3413k1	394	1	Airway	Airway	NNP
cord-309556-xv3413k1	394	2	Smooth	Smooth	NNP
cord-309556-xv3413k1	394	3	Muscle	Muscle	NNP
cord-309556-xv3413k1	394	4	Function	Function	NNP
cord-309556-xv3413k1	394	5	SARS	SARS	NNP
cord-309556-xv3413k1	394	6	-	-	:
cord-309556-xv3413k1	394	7	CoV-2	CoV-2	NNP
cord-309556-xv3413k1	394	8	launches	launch	VBZ
cord-309556-xv3413k1	394	9	a	a	DT
cord-309556-xv3413k1	394	10	unique	unique	JJ
cord-309556-xv3413k1	394	11	transcriptional	transcriptional	JJ
cord-309556-xv3413k1	394	12	signature	signature	NN
cord-309556-xv3413k1	394	13	from	from	IN
cord-309556-xv3413k1	394	14	in	in	IN
cord-309556-xv3413k1	394	15	vitro	vitro	FW
cord-309556-xv3413k1	394	16	,	,	,
cord-309556-xv3413k1	394	17	ex	ex	FW
cord-309556-xv3413k1	394	18	vivo	vivo	NN
cord-309556-xv3413k1	394	19	,	,	,
cord-309556-xv3413k1	394	20	and	and	CC
cord-309556-xv3413k1	394	21	in	in	IN
cord-309556-xv3413k1	394	22	vivo	vivo	NNP
cord-309556-xv3413k1	394	23	systems	system	NNS
cord-309556-xv3413k1	395	1	A	a	DT
cord-309556-xv3413k1	395	2	microphysiological	microphysiological	JJ
cord-309556-xv3413k1	395	3	model	model	NN
cord-309556-xv3413k1	395	4	of	of	IN
cord-309556-xv3413k1	395	5	the	the	DT
cord-309556-xv3413k1	395	6	bronchial	bronchial	NNP
cord-309556-xv3413k1	395	7	airways	airways	NNP
cord-309556-xv3413k1	395	8	reveals	reveal	VBZ
cord-309556-xv3413k1	395	9	the	the	DT
cord-309556-xv3413k1	395	10	interplay	interplay	NN
cord-309556-xv3413k1	395	11	of	of	IN
cord-309556-xv3413k1	395	12	mechanical	mechanical	JJ
cord-309556-xv3413k1	395	13	and	and	CC
cord-309556-xv3413k1	395	14	biochemical	biochemical	JJ
cord-309556-xv3413k1	395	15	signals	signal	NNS
cord-309556-xv3413k1	395	16	in	in	IN
cord-309556-xv3413k1	395	17	bronchospasm	bronchospasm	JJ
cord-309556-xv3413k1	395	18	Systematic	systematic	JJ
cord-309556-xv3413k1	395	19	and	and	CC
cord-309556-xv3413k1	395	20	integrative	integrative	JJ
cord-309556-xv3413k1	395	21	analysis	analysis	NN
cord-309556-xv3413k1	395	22	of	of	IN
cord-309556-xv3413k1	395	23	large	large	JJ
cord-309556-xv3413k1	395	24	gene	gene	NN
cord-309556-xv3413k1	395	25	lists	list	NNS
cord-309556-xv3413k1	395	26	using	use	VBG
cord-309556-xv3413k1	395	27	DAVID	DAVID	NNP
cord-309556-xv3413k1	395	28	bioinformatics	bioinformatics	NN
cord-309556-xv3413k1	395	29	resources	resource	NNS
cord-309556-xv3413k1	395	30	Integrating	integrate	VBG
cord-309556-xv3413k1	395	31	single	single	JJ
cord-309556-xv3413k1	395	32	-	-	HYPH
cord-309556-xv3413k1	395	33	cell	cell	NN
cord-309556-xv3413k1	395	34	transcriptomic	transcriptomic	JJ
cord-309556-xv3413k1	395	35	data	datum	NNS
cord-309556-xv3413k1	395	36	across	across	IN
cord-309556-xv3413k1	395	37	different	different	JJ
cord-309556-xv3413k1	395	38	conditions	condition	NNS
cord-309556-xv3413k1	395	39	,	,	,
cord-309556-xv3413k1	395	40	technologies	technology	NNS
cord-309556-xv3413k1	395	41	,	,	,
cord-309556-xv3413k1	395	42	and	and	CC
cord-309556-xv3413k1	395	43	species	specie	VBZ
cord-309556-xv3413k1	395	44	Comprehensive	Comprehensive	NNP
cord-309556-xv3413k1	395	45	Integration	Integration	NNP
cord-309556-xv3413k1	395	46	of	of	IN
cord-309556-xv3413k1	395	47	Single	Single	NNP
cord-309556-xv3413k1	395	48	-	-	HYPH
cord-309556-xv3413k1	395	49	Cell	Cell	NNP
cord-309556-xv3413k1	395	50	Data	Data	NNP
cord-309556-xv3413k1	395	51	A	a	DT
cord-309556-xv3413k1	395	52	flexible	flexible	JJ
cord-309556-xv3413k1	395	53	R	r	NN
cord-309556-xv3413k1	395	54	package	package	NN
cord-309556-xv3413k1	395	55	for	for	IN
cord-309556-xv3413k1	395	56	nonnegative	nonnegative	JJ
cord-309556-xv3413k1	395	57	matrix	matrix	NN
cord-309556-xv3413k1	395	58	factorization	factorization	NN
cord-309556-xv3413k1	395	59	Superheat	superheat	NN
cord-309556-xv3413k1	395	60	:	:	:
cord-309556-xv3413k1	395	61	An	an	DT
cord-309556-xv3413k1	395	62	R	r	NN
cord-309556-xv3413k1	395	63	Package	package	NN
cord-309556-xv3413k1	395	64	for	for	IN
cord-309556-xv3413k1	395	65	Creating	create	VBG
cord-309556-xv3413k1	395	66	Beautiful	beautiful	JJ
cord-309556-xv3413k1	395	67	and	and	CC
cord-309556-xv3413k1	395	68	Extendable	extendable	JJ
cord-309556-xv3413k1	395	69	Heatmaps	Heatmaps	NNP
cord-309556-xv3413k1	395	70	for	for	IN
cord-309556-xv3413k1	395	71	Visualizing	visualize	VBG
cord-309556-xv3413k1	395	72	Complex	Complex	NNP
cord-309556-xv3413k1	395	73	Data	Data	NNP