id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-223292-ct8xyntw	Lemey, Philippe	The seasonal flight of influenza: a unified framework for spatiotemporal hypothesis testing	2012-10-22		.txt	text/plain	4009	174	36	Because passenger flux emerged as the main predictor in our phylogeographic model (see 3.3.1), we also identified discrete air communities in the worldwide air transportation network (see 3.2.1) and applied these as location states to our sequence sample. We integrate genetic, spatial and air transportation data within a single full probabilistic evolutionary model and simultaneously estimate the parameters of phylogeographic diffusion using Markov chain Monte Carlo (MCMC) analysis implemented in BEAST [23] . To test the impact of sampling effects, we considered origin and destination sample sizes (number of H3N2 sequences included per discrete location state in the phylogeographic analysis) as separate predictors. To identify key factors in seasonal influenza dispersal, we inferred the phylogeographic history of globally sampled A/H3N2 viruses between 2002 and 2007, while simultaneously evaluating the contribution of several potential diffusion predictors using a novel Bayesian model selection procedure.	./cache/cord-223292-ct8xyntw.txt	./txt/cord-223292-ct8xyntw.txt