id author title date pages extension mime words sentences flesch summary cache txt cord-304972-aktfbriw Cots, Josep M. Recommendations for Management of Acute Pharyngitis in Adults 2015-06-30 .txt text/plain 6000 439 51 4---7 In normal practice, a diagnosis is made based on clinical criteria (fever, tonsillar exudate, anterior cervical lymphadenopathy and no cough), which are of low sensitivity in predicting GABHS (49%---74%), and therefore the indication for the prescription of antibiotics increases as there are a great many false positives. Validity depends on the sample collection technique (false-negative results can be given when little material has been obtained), on the area from which it is collected (there is a better yield when collected from the tonsils and/or the wall posterior to the pharynx), on the culture procedure and conditions, on the probability of streptococcal infection (some authors have found a spectrum bias, so that the sensitivity of Strep A increases the higher the Centor criteria number presented by a patient), the presence of other germs in the pharynx (false-positive results can be given if the pharynx presents major growth of Staphylococcus aureus), on the use of tests which are past their expiry date, and on commercial brand. ./cache/cord-304972-aktfbriw.txt ./txt/cord-304972-aktfbriw.txt