id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001493-3yu2di1g	Fujishima, Seitaro	Pathophysiology and biomarkers of acute respiratory distress syndrome	2014-05-07		.txt	text/plain	3096	159	36	Acute respiratory distress syndrome (ARDS) is defined as an acute-onset, progressive, hypoxic condition with radiographic bilateral lung infiltration, which develops after several diseases or injuries, and is not derived from hydrostatic pulmonary edema. In parallel with progress in understanding the pathophysiology of ARDS, various humoral factors induced by inflammation and molecules derived from activated cells or injured tissues have been shown as potential biomarkers that may be applied in clinical practice. Numerous proinflammatory cytokines play major roles in acute inflammation and the development of inflammatory lung diseases, including ARDS. Increased levels of soluble receptor for advanced glycation end products (sRAGE) and high mobility group box 1 (HMGB1) are associated with death in patients with acute respiratory distress syndrome Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients Acute Respiratory Distress Syndrome Network: Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury	./cache/cord-001493-3yu2di1g.txt	./txt/cord-001493-3yu2di1g.txt