id author title date pages extension mime words sentences flesch summary cache txt cord-001661-dj9bxhwb Kao, Kuo-Chin Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy 2015-05-15 .txt text/plain 4381 218 46 title: Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy INTRODUCTION: Diffuse alveolar damage (DAD) is the pathological hallmark of acute respiratory distress syndrome (ARDS), however, the presence of DAD in the clinical criteria of ARDS patients by Berlin definition is little known. A pathological finding of DAD in ARDS patients is associated with hospital mortality and there are no clinical characteristics that could identify DAD patients before open lung biopsy. The following data were collected from the hospital chart of each patient and analyzed: age, sex, underlying diseases, acute physiology and chronic health evaluation (APACHE) II score on the day of ICU admission [28] , sequential organ failure assessment (SOFA) score on the day of ICU admission and the day of open lung biopsy [29] , lung injury score (LIS) [30] , PaO 2 /FiO 2 ratio, PEEP, tidal volume, diagnostic procedures before open lung biopsy (HRCT or BAL), complications related to surgery (i.e., postoperative air leak, pneumothorax, subcutaneous emphysema, bleeding, and wound infection), pathological diagnosis, hospital mortality, and therapeutic alterations. ./cache/cord-001661-dj9bxhwb.txt ./txt/cord-001661-dj9bxhwb.txt