id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-002540-hgx0bfbz	Chen, Chaolei	Can glypican-3 be a disease-specific biomarker?	2017-05-16		.txt	text/plain	3085	147	34	BACKGROUND: Glypican-3 (GPC3) is a cell surface-bound proteoglycan which has been identified as a potential biomarker candidate in hepatocellular carcinoma, lung carcinoma, severe pneumonia, and acute respiratory distress syndrome (ARDS). The aim of our review is to evaluate whether GPC3 has utility as a disease-specific biomarker, to discuss the potential involvement of GPC3 in cell biology, and to consider the changes of GPC3 gene and protein expression and regulation in hepatocellular carcinoma, lung cancer, severe pneumonia, and ARDS. Specific role of GPC3 in cancer and inflammatory disease at different times seems to have a clear and reasonable disease control, e.g., severe pneumonia with or without ARDS, or virus-infected patients with hepatocellular carcinoma compared with other liver diseases [3, 4] .	./cache/cord-002540-hgx0bfbz.txt	./txt/cord-002540-hgx0bfbz.txt