id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005511-h5d2v4ga	Ospina-Tascón, Gustavo A.	Microcirculatory dysfunction and dead-space ventilation in early ARDS: a hypothesis-generating observational study	2020-03-24		.txt	text/plain	5219	275	44	We sought to evaluate the relationships between dynamic variations in V(D)/V(T) and extra-pulmonary microcirculatory blood flow detected at sublingual mucosa hypothesizing that an altered microcirculation, which is a generalized phenomenon during severe inflammatory conditions, could influence ventilation/perfusion mismatching manifested by increases in V(D)/V(T) fraction during early stages of ARDS. Thus, considering microcirculatory dysfunction during inflammatory conditions as a generalized phenomenon, which may involve systemic and pulmonary vascular beds, we hypothesized that alterations in microvascular blood flow distribution evaluated at the sublingual mucosa as representative of an extra-pulmonary territory could be related to variations in dead-space ventilation V D /V T during early phases of moderate and severe ARDS.	./cache/cord-005511-h5d2v4ga.txt	./txt/cord-005511-h5d2v4ga.txt